cyproheptadine has been researched along with Aldosteronism in 3 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study the role of serotonin in regulating the release of aldosterone, we gave single, oral doses of cyproheptadine, an antiserotoninergic agent, to five normal volunteers with high aldosterone levels secondary to sodium deprivation and to 14 patients with aldosteronism (six with idiopathic aldosteronism due to bilateral adrenal hyperplasia and eight with adrenal adenoma)." | 7.66 | Suppression of aldosterone by cyproheptadine in idiopathic aldosteronism. ( Gniadek, TC; Grekin, RJ; Gross, MD; Villareal, JZ, 1981) |
| "To study the role of serotonin in regulating the release of aldosterone, we gave single, oral doses of cyproheptadine, an antiserotoninergic agent, to five normal volunteers with high aldosterone levels secondary to sodium deprivation and to 14 patients with aldosteronism (six with idiopathic aldosteronism due to bilateral adrenal hyperplasia and eight with adrenal adenoma)." | 3.66 | Suppression of aldosterone by cyproheptadine in idiopathic aldosteronism. ( Gniadek, TC; Grekin, RJ; Gross, MD; Villareal, JZ, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ben-Yosef, S | 1 |
| Knobel, B | 1 |
| Krispin, M | 1 |
| Zaidel, L | 1 |
| Gross, MD | 1 |
| Grekin, RJ | 1 |
| Gniadek, TC | 1 |
| Villareal, JZ | 1 |
3 other studies available for cyproheptadine and Aldosteronism
| Article | Year |
|---|---|
[Hyporeninemic hyperaldosteronism due to aldosteronoma].
Topics: Adrenal Gland Neoplasms; Aldosterone; Cyproheptadine; Diagnosis, Differential; Female; Humans; Hyper | 1982 |
Suppression of aldosterone by cyproheptadine in idiopathic aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Cyproheptadine; Depression, Chemical; Diet, So | 1981 |
Cyproheptadine in idiopathic aldosteronism.
Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Cyproheptadine; Dexamethasone; Drug Synergism; Humans | 1981 |