cyproheptadine has been researched along with Aging in 10 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with cyproheptadine and vinblastine, however, prevented only the increased permeability of the blood-brain barrier; the plasma and level of 5-HT in brain continued to remain high." | 1.27 | Probable involvement of 5-hydroxytryptamine in increased permeability of blood-brain barrier under heat stress in young rats. ( Dey, PK; Sharma, HS, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (50.00) | 18.7374 |
| 1990's | 4 (40.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Petrascheck, M | 1 |
| Ye, X | 1 |
| Buck, LB | 1 |
| Wedderburn, JF | 1 |
| Sillar, KT | 1 |
| Sharma, HS | 2 |
| Westman, J | 1 |
| Navarro, JC | 1 |
| Dey, PK | 2 |
| Nyberg, F | 1 |
| Moyanova, S | 1 |
| Kortenska, L | 1 |
| Kirov, R | 1 |
| Dunn, CJ | 1 |
| Willoughby, DA | 1 |
| Blackford, SP | 1 |
| Little, PJ | 1 |
| Kuhn, CM | 3 |
| Bero, LA | 2 |
| Kuhn, C | 1 |
| Bero, L | 1 |
| Ignar, D | 1 |
| Lurie, S | 1 |
| Field, E | 1 |
10 other studies available for cyproheptadine and Aging
| Article | Year |
|---|---|
An antidepressant that extends lifespan in adult Caenorhabditis elegans.
Topics: Aging; Animals; Antidepressive Agents; Caenorhabditis elegans; Caloric Restriction; Humans; Longevit | 2007 |
Modulation of rhythmic swimming activity in post-embryonic Xenopus laevis tadpoles by 5-hydroxytryptamine acting at 5HT1a receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Cyproheptadine; Ergolines; Ketanserin; Metam | 1994 |
Probable involvement of serotonin in the increased permeability of the blood-brain barrier by forced swimming. An experimental study using Evans blue and 131I-sodium tracers in the rat.
Topics: 5,7-Dihydroxytryptamine; Aging; Animals; Antineoplastic Agents, Phytogenic; Blood Pressure; Blood-Br | 1995 |
High-voltage electroencephalogram spindles in rats, aging and 5-HT2 antagonism.
Topics: Aging; Alpha Rhythm; Animals; Cyproheptadine; Electroencephalography; Ketanserin; Male; Rats; Rats, | 1998 |
The response of the newborn rat to intraleural dextran: vascular and cellular aspects.
Topics: Aging; Animals; Animals, Newborn; Cyproheptadine; Dextrans; Edema; Exudates and Transudates; Hindlim | 1975 |
Mu- and kappa-opiate receptor control of prolactin secretion in rats: ontogeny and interaction with serotonin.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Aging; Ani | 1992 |
Role of serotonin in opiate-induced prolactin secretion and antinociception in the developing rat.
Topics: 5,7-Dihydroxytryptamine; Aging; Animals; Animals, Newborn; Cyproheptadine; Hydroxyindoleacetic Acid; | 1987 |
Probable involvement of 5-hydroxytryptamine in increased permeability of blood-brain barrier under heat stress in young rats.
Topics: Aging; Animals; Blood Pressure; Blood-Brain Barrier; Body Temperature; Cyproheptadine; Diazepam; Fem | 1986 |
Differential ontogeny of opioid, dopaminergic and serotonergic regulation of prolactin secretion.
Topics: 5-Hydroxytryptophan; Aging; Animals; Animals, Newborn; Corticosterone; Cyproheptadine; Fluoxetine; G | 1987 |
Endocrine consequences of perinatal methadone exposure.
Topics: Aging; Animals; Animals, Newborn; Cyproheptadine; Disease Models, Animal; Hypothalamo-Hypophyseal Sy | 1987 |