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cyproheptadine and Adrenal Cancer

cyproheptadine has been researched along with Adrenal Cancer in 7 studies

Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.

Research Excerpts

ExcerptRelevanceReference
"To study the role of serotonin in regulating the release of aldosterone, we gave single, oral doses of cyproheptadine, an antiserotoninergic agent, to five normal volunteers with high aldosterone levels secondary to sodium deprivation and to 14 patients with aldosteronism (six with idiopathic aldosteronism due to bilateral adrenal hyperplasia and eight with adrenal adenoma)."7.66Suppression of aldosterone by cyproheptadine in idiopathic aldosteronism. ( Gniadek, TC; Grekin, RJ; Gross, MD; Villareal, JZ, 1981)
"To study the role of serotonin in regulating the release of aldosterone, we gave single, oral doses of cyproheptadine, an antiserotoninergic agent, to five normal volunteers with high aldosterone levels secondary to sodium deprivation and to 14 patients with aldosteronism (six with idiopathic aldosteronism due to bilateral adrenal hyperplasia and eight with adrenal adenoma)."3.66Suppression of aldosterone by cyproheptadine in idiopathic aldosteronism. ( Gniadek, TC; Grekin, RJ; Gross, MD; Villareal, JZ, 1981)
"Treatment with metyrapone or o,p'-DDD can always induce a clinical remission but not a cure, and neurotransmitter therapy may be effective in a minority of cases."2.37Cushing's syndrome. ( Besser, GM; Howlett, TA; Rees, LH, 1985)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19907 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ben-Yosef, S1
Knobel, B1
Krispin, M1
Zaidel, L1
Gross, MD1
Grekin, RJ1
Gniadek, TC1
Villareal, JZ1
Bricaire, H1
Luton, JP1
McPherson, HT1
Krieger, DT1
Howlett, TA1
Rees, LH1
Besser, GM1

Reviews

2 reviews available for cyproheptadine and Adrenal Cancer

ArticleYear
Cushing's syndrome.
    The Urologic clinics of North America, 1977, Volume: 4, Issue:2

    Topics: Adolescent; Adrenal Cortex Function Tests; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrena

1977
Cushing's syndrome.
    Clinics in endocrinology and metabolism, 1985, Volume: 14, Issue:4

    Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Alcoho

1985

Other Studies

5 other studies available for cyproheptadine and Adrenal Cancer

ArticleYear
[Hyporeninemic hyperaldosteronism due to aldosteronoma].
    Harefuah, 1982, Nov-01, Volume: 103, Issue:9

    Topics: Adrenal Gland Neoplasms; Aldosterone; Cyproheptadine; Diagnosis, Differential; Female; Humans; Hyper

1982
Suppression of aldosterone by cyproheptadine in idiopathic aldosteronism.
    The New England journal of medicine, 1981, Jul-23, Volume: 305, Issue:4

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Cyproheptadine; Depression, Chemical; Diet, So

1981
[Cushing's syndrome. Medical treatment of adrenal hypercorticism].
    Hormone research, 1980, Volume: 13, Issue:4-5

    Topics: Adrenal Gland Neoplasms; Aminoglutethimide; Androstanols; Bromocriptine; Cushing Syndrome; Cyprohept

1980
Cyproheptadine in idiopathic aldosteronism.
    The New England journal of medicine, 1981, Nov-12, Volume: 305, Issue:20

    Topics: Adenoma; Adrenal Gland Neoplasms; Aldosterone; Cyproheptadine; Dexamethasone; Drug Synergism; Humans

1981
The central nervous system and Cushing's disease.
    The Medical clinics of North America, 1978, Volume: 62, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Central Nervous Syste

1978