cyproheptadine has been researched along with Adenoma, beta-Cell in 2 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The RINm5F cell insulin assay enabled the identification of aryl-aryl-amine DOR agonists that lacked an insulin-reducing effect and did not elevate blood glucose in repeated dosing studies conducted over a suprapharmacologic dose range." | 1.36 | Diabetogenic effect of a series of tricyclic delta opioid agonists structurally related to cyproheptadine. ( Baker, J; Brandt, MR; Bryant, S; Cai, C; Carson, JR; Chevalier, KM; Codd, EE; Colburn, RW; Coogan, TP; Dax, SL; Decorte, B; Flores, CM; Kemmerer, M; Legrand, EK; Lenhard, JM; Leone, AM; Lin, L; Mabus, JR; McDonnell, ME; McMillian, MK; McNally, JJ; Stone, DJ; Wang, CY; Zhang, SP, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Codd, EE | 1 |
| Baker, J | 1 |
| Brandt, MR | 1 |
| Bryant, S | 1 |
| Cai, C | 1 |
| Carson, JR | 1 |
| Chevalier, KM | 1 |
| Colburn, RW | 1 |
| Coogan, TP | 1 |
| Dax, SL | 1 |
| Decorte, B | 1 |
| Kemmerer, M | 1 |
| Legrand, EK | 1 |
| Lenhard, JM | 1 |
| Leone, AM | 1 |
| Lin, L | 1 |
| Mabus, JR | 1 |
| McDonnell, ME | 1 |
| McMillian, MK | 1 |
| McNally, JJ | 1 |
| Stone, DJ | 1 |
| Wang, CY | 1 |
| Zhang, SP | 1 |
| Flores, CM | 1 |
| Miller, CP | 1 |
| Reape, TJ | 1 |
| Fischer, LJ | 1 |
2 other studies available for cyproheptadine and Adenoma, beta-Cell
| Article | Year |
|---|---|
Diabetogenic effect of a series of tricyclic delta opioid agonists structurally related to cyproheptadine.
Topics: Animals; Blood Glucose; Cell Enlargement; Cell Line, Tumor; Cyproheptadine; Diabetes Mellitus, Type | 2010 |
Inhibition of insulin production by cyproheptadine in RINm5F rat insulinoma cells.
Topics: Animals; Blotting, Northern; Cyproheptadine; DNA; Indicators and Reagents; Insulin; Insulinoma; Panc | 1993 |