cyproheptadine has been researched along with Addison Disease in 2 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
Addison Disease: An adrenal disease characterized by the progressive destruction of the ADRENAL CORTEX, resulting in insufficient production of ALDOSTERONE and HYDROCORTISONE. Clinical symptoms include ANOREXIA; NAUSEA; WEIGHT LOSS; MUSCLE WEAKNESS; and HYPERPIGMENTATION of the SKIN due to increase in circulating levels of ACTH precursor hormone which stimulates MELANOCYTES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In 14 patients with Addison's disease plasma levels of ACTH were studied after administration of a single oral dose (16 mg) of cyproheptadine." | 7.66 | Inhibitory effect of cyproheptadine on ACTH secretion in patients with Addison's disease. ( Frascatani, F; Gelli, D; Loli, P; Maggioni, M; Muratori, F; Ronzoni, M, 1983) |
| "In 14 patients with Addison's disease plasma levels of ACTH were studied after administration of a single oral dose (16 mg) of cyproheptadine." | 3.66 | Inhibitory effect of cyproheptadine on ACTH secretion in patients with Addison's disease. ( Frascatani, F; Gelli, D; Loli, P; Maggioni, M; Muratori, F; Ronzoni, M, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Loli, P | 1 |
| Frascatani, F | 1 |
| Gelli, D | 1 |
| Maggioni, M | 1 |
| Muratori, F | 1 |
| Ronzoni, M | 1 |
| Fehm, HL | 1 |
| Voigt, KH | 1 |
| Kummer, G | 1 |
| Retiene, K | 1 |
| Pfeiffer, EF | 1 |
2 other studies available for cyproheptadine and Addison Disease
| Article | Year |
|---|---|
Inhibitory effect of cyproheptadine on ACTH secretion in patients with Addison's disease.
Topics: Addison Disease; Adrenocorticotropic Hormone; Adult; Cyproheptadine; Female; Humans; Male; Middle Ag | 1983 |
[Inhibition of ACTH hypersecretion in Addison's disease by serotonin-antagonistic agents].
Topics: Addison Disease; Adrenocorticotropic Hormone; Cyproheptadine; Humans; Serotonin Antagonists | 1978 |