cyproheptadine has been researched along with Absence Seizure in 12 studies
Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "She had a seizure and required sedation and intubation." | 5.62 | Two Cases of Serotonin Syndrome After Bupropion Overdose Treated With Cyproheptadine. ( Beau, J; Bolton, TA; Carpenter, JE; Kazzi, Z; Kiernan, EA; Murray, BP; Sayers, J; Wolf, MJ; Yeh, M, 2021) |
| "She had a seizure and required sedation and intubation." | 1.62 | Two Cases of Serotonin Syndrome After Bupropion Overdose Treated With Cyproheptadine. ( Beau, J; Bolton, TA; Carpenter, JE; Kazzi, Z; Kiernan, EA; Murray, BP; Sayers, J; Wolf, MJ; Yeh, M, 2021) |
| "Seizures were significantly increased in rats receiving 80% and 120% of citalopram MLD versus controls (p<0." | 1.38 | Mechanisms of high-dose citalopram-induced death in a rat model. ( Baud, FJ; Beaune, S; Callebert, J; Juvin, P; Mégarbane, B; Risède, P, 2012) |
| "In the present study convulsions were induced in mice by, maximum electroshock (MES), picrotoxin, and pentylenetetrazol (PTZ)." | 1.36 | Proconvulsant potential of cyproheptadine in experimental animal models. ( Goel, RK; Singh, D, 2010) |
| "In this study, electroconvulsion was induced by stimulating rats using ear-clip electrodes, and the durations of electroencephalogram (EEG) seizure, tonic extensor (TE) seizure and clonic (CL) seizure induced by maximal electroshock were measured." | 1.34 | Influences of histamine H1 receptor antagonists on maximal electroshock seizure in infant rats. ( Ago, J; Ishikawa, T; Kamei, C; Matsumoto, N; Murakami, A; Rahman, A; Takechi, K, 2007) |
| "Cyproheptadine is an agent with considerable side effects, and it should be prescribed to children only after very careful deliberation." | 1.26 | [Toxicity of cyproheptadine. Side effects and accidental overdosage (author's transl)]. ( Krienke, EG; von Mühlendahl, KE, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (50.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Murray, BP | 1 |
| Carpenter, JE | 1 |
| Sayers, J | 1 |
| Yeh, M | 1 |
| Beau, J | 1 |
| Kiernan, EA | 1 |
| Wolf, MJ | 1 |
| Bolton, TA | 1 |
| Kazzi, Z | 1 |
| Faingold, CL | 1 |
| Kommajosyula, SP | 1 |
| Long, X | 1 |
| Plath, K | 1 |
| Randall, M | 1 |
| Singh, D | 1 |
| Goel, RK | 1 |
| Beaune, S | 1 |
| Callebert, J | 1 |
| Baud, FJ | 1 |
| Risède, P | 1 |
| Juvin, P | 1 |
| Mégarbane, B | 1 |
| Ishikawa, T | 1 |
| Takechi, K | 1 |
| Rahman, A | 1 |
| Ago, J | 1 |
| Matsumoto, N | 1 |
| Murakami, A | 1 |
| Kamei, C | 1 |
| Semenova, TP | 1 |
| Riku, MK | 1 |
| Kähling, J | 1 |
| Ziegler, H | 1 |
| Ballhause, H | 1 |
| von Mühlendahl, KE | 1 |
| Krienke, EG | 1 |
| Khanna, N | 1 |
| Ray, A | 1 |
| Alkondon, M | 1 |
| Sen, P | 1 |
| Sharma, VN | 1 |
| Vyas, DS | 1 |
| Madan, BR | 1 |
| Clineschmidt, BV | 1 |
| Lotti, VJ | 1 |
| van Riezen, H | 1 |
12 other studies available for cyproheptadine and Absence Seizure
| Article | Year |
|---|---|
Two Cases of Serotonin Syndrome After Bupropion Overdose Treated With Cyproheptadine.
Topics: Adolescent; Adult; Bupropion; Cyproheptadine; Drug Overdose; Female; Humans; Male; Seizures; Seroton | 2021 |
Serotonin and sudden death: differential effects of serotonergic drugs on seizure-induced respiratory arrest in DBA/1 mice.
Topics: Adrenergic Uptake Inhibitors; Animals; Cyclohexanols; Cyproheptadine; Death, Sudden; Dose-Response R | 2014 |
Proconvulsant potential of cyproheptadine in experimental animal models.
Topics: Animals; Anticonvulsants; Cyproheptadine; Disease Models, Animal; Drug Interactions; Histamine H1 An | 2010 |
Mechanisms of high-dose citalopram-induced death in a rat model.
Topics: Animals; Body Temperature; Citalopram; Cyproheptadine; Diazepam; Dose-Response Relationship, Drug; L | 2012 |
Influences of histamine H1 receptor antagonists on maximal electroshock seizure in infant rats.
Topics: Administration, Oral; Animals; Animals, Suckling; Chlorpheniramine; Cyproheptadine; Dibenzazepines; | 2007 |
[The role of the interaction of various types of serotonin- and alpha 2-adrenoreceptors in regulating audiogenic seizures in DBA/2 mice].
Topics: Acoustic Stimulation; Adrenergic alpha-2 Receptor Antagonists; Animals; Cyproheptadine; Mianserin; M | 1995 |
[Central action of WA-335-BS, a substance with peripheral antiserotonin and antihistaminic activity].
Topics: Aggression; Animals; Anthracenes; Anxiety; Appetite; Arousal; Behavior, Animal; Body Temperature; Ca | 1975 |
[Toxicity of cyproheptadine. Side effects and accidental overdosage (author's transl)].
Topics: Ataxia; Child; Child, Preschool; Cyproheptadine; Female; Hallucinations; Humans; Infant; Male; Pupil | 1978 |
Effect of beta-adrenoceptor antagonists and some related drugs on maximal electroshock seizures in mice.
Topics: Adrenergic beta-Antagonists; Animals; Atropine; Cyproheptadine; Electroshock; Female; Indomethacin; | 1989 |
A study of the antiarrhythmic and anticonvulsant activity of three new antihistamines.
Topics: Animals; Anti-Arrhythmia Agents; Anticonvulsants; Arrhythmias, Cardiac; Cyproheptadine; Dogs; Ethyla | 1968 |
Indoleamine antagonists: relative potencies as inhibitors of tryptamine- and 5-hydroxytryptophan-evoked responses.
Topics: 5-Hydroxytryptophan; Anilides; Animals; Cinnamates; Cyproheptadine; Ergolines; Female; Foot; Head; M | 1974 |
Different central effects of the 5-HT antagonists mianserine and cyproheptadine.
Topics: Animals; Behavior, Animal; Cyproheptadine; Dibenzazepines; Drug Antagonism; Electroshock; Lethal Dos | 1972 |