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cyproheptadine and Abdominal Pain

cyproheptadine has been researched along with Abdominal Pain in 6 studies

Cyproheptadine: A serotonin antagonist and a histamine H1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.
cyproheptadine : The product resulting from the formal oxidative coupling of position 5 of 5H-dibenzo[a,d]cycloheptene with position 4 of 1-methylpiperidine resulting in the formation of a double bond between the two fragments. It is a sedating antihistamine with antimuscarinic and calcium-channel blocking actions. It is used (particularly as the hydrochloride sesquihydrate) for the relief of allergic conditions including rhinitis, conjunctivitis due to inhalant allergens and foods, urticaria and angioedema, and in pruritic skin disorders. Unlike other antihistamines, it is also a seratonin receptor antagonist, making it useful in conditions such as vascular headache and anorexia.

Abdominal Pain: Sensation of discomfort, distress, or agony in the abdominal region.

Research Excerpts

ExcerptRelevanceReference
"By week 1 and 2 of the intervention, the intensity and frequency of abdominal pain among the patients treated with cyproheptadine, were rated as complete resolved and very much improved or improved for 3 (20%), 10 (66."9.13Cyproheptadine for the treatment of functional abdominal pain in childhood: a double-blinded randomized placebo-controlled trial. ( Abbasi, A; Fallahi, GH; Farahmand, F; Sadeghian, M, 2008)
"By week 1 and 2 of the intervention, the intensity and frequency of abdominal pain among the patients treated with cyproheptadine, were rated as complete resolved and very much improved or improved for 3 (20%), 10 (66."5.13Cyproheptadine for the treatment of functional abdominal pain in childhood: a double-blinded randomized placebo-controlled trial. ( Abbasi, A; Fallahi, GH; Farahmand, F; Sadeghian, M, 2008)
" There are four separate strands of evidence for this: the common co-existence of abdominal pain and migraine headaches; the similarity between children with episodic abdominal pain and children with migraine headaches, with respect to social and demographic factors, precipitating and relieving factors, and accompanying gastrointestinal, neurological and vasomotor features; the effectiveness of nonanalgesic migraine therapy (such as pizotifen, propanolol, cyproheptadine and the triptans) in abdominal migraine; and the finding of similar neurophysiological features in both migraine headache and abdominal migraine."4.81Abdominal migraine: evidence for existence and treatment options. ( Abu-Arafeh, I; Russell, G; Symon, DN, 2002)
"Patients with abdominal migraine may benefit from prophylactic treatment with propranolol or cyproheptadine."3.70Abdominal migraine: prophylactic treatment and follow-up. ( Lichtman, SN; Rhoads, JM; Ulshen, MH; Worawattanakul, M, 1999)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's3 (50.00)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rosen, JM1
Alioto, A1
Saps, M2
Sadeghian, M1
Farahmand, F1
Fallahi, GH1
Abbasi, A1
Bonilla, S1
Ruiz, C1
Gener, B1
Garaizar, C1
Prats, JM1
Worawattanakul, M1
Rhoads, JM1
Lichtman, SN1
Ulshen, MH1
Russell, G1
Abu-Arafeh, I1
Symon, DN1

Reviews

2 reviews available for cyproheptadine and Abdominal Pain

ArticleYear
Advances in Pain-Predominant Functional Gastrointestinal Disorders in the Adolescent.
    Adolescent medicine: state of the art reviews, 2016,Spring, Volume: 27, Issue:1

    Topics: Abdominal Pain; Adolescent; Amitriptyline; Antidepressive Agents, Tricyclic; Cognitive Behavioral Th

2016
Abdominal migraine: evidence for existence and treatment options.
    Paediatric drugs, 2002, Volume: 4, Issue:1

    Topics: Abdominal Pain; Child; Cyproheptadine; Diet; Humans; Migraine Disorders; Pizotyline; Propranolol; Se

2002

Trials

1 trial available for cyproheptadine and Abdominal Pain

ArticleYear
Cyproheptadine for the treatment of functional abdominal pain in childhood: a double-blinded randomized placebo-controlled trial.
    Minerva pediatrica, 2008, Volume: 60, Issue:6

    Topics: Abdominal Pain; Chi-Square Distribution; Child; Child, Preschool; Cyproheptadine; Data Interpretatio

2008

Other Studies

3 other studies available for cyproheptadine and Abdominal Pain

ArticleYear
Pharmacological treatment of abdominal pain related functional gastrointestinal disorders.
    Journal of pediatric gastroenterology and nutrition, 2011, Volume: 53 Suppl 2

    Topics: Abdominal Pain; Antidepressive Agents; Cyproheptadine; Gastrointestinal Diseases; Histamine H2 Antag

2011
Episodic spontaneous hypothermia: a periodic childhood syndrome.
    Pediatric neurology, 2003, Volume: 28, Issue:4

    Topics: Abdominal Pain; Body Temperature; Bradycardia; Child; Child, Preschool; Consciousness Disorders; Cyp

2003
Abdominal migraine: prophylactic treatment and follow-up.
    Journal of pediatric gastroenterology and nutrition, 1999, Volume: 28, Issue:1

    Topics: Abdominal Pain; Adolescent; Child; Child, Preschool; Cyproheptadine; Female; Gastrointestinal Agents

1999