cypellocarpin-c and Skin-Neoplasms

cypellocarpin-c has been researched along with Skin-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for cypellocarpin-c and Skin-Neoplasms

ArticleYear
Cypellocarpins A-C, phenol glycosides esterified with oleuropeic acid, from Eucalyptus cypellocarpa.
    Journal of natural products, 2000, Volume: 63, Issue:9

    Three new phenol glycosides acylated with (+)-oleuropeic acid, cypellocarpins A (1), B (2), and C (3), along with seven known compounds, were isolated from the dried leaves of Eucalyptus cypellocarpa. Structures of the new compounds were determined on the basis of spectroscopic methods, including 2D NMR experiments and chemical degradation. These new compounds and a known related glucoside (7) showed potent in vitro antitumor-promoting activity in a short-term bioassay evaluating the inhibitory effect on Epstein-Barr virus early antigen activation induced by 12-O-tetradecanoyl phorbol 13-acetate (TPA). These compounds also suppressed an in vivo two-stage carcinogenesis induced with nitric oxide and TPA on mouse skin.

    Topics: Animals; Anticarcinogenic Agents; Cell Line; Cyclohexanecarboxylic Acids; Esterification; Eucalyptus; Female; Glucosides; Glycosides; Herpesvirus 4, Human; Humans; Mice; Papilloma; Plants, Medicinal; Skin Neoplasms; Spectrum Analysis; Virus Activation

2000