cyclothiazide has been researched along with Nerve Degeneration in 2 studies
cyclothiazide: inhibits the desensitization of AMPA-type receptors; structure
cyclothiazide : 3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted at positions 3, 5 and 6 by a 2-norbornen-5-yl group, chlorine, and a sulfonamide group, respectively. A thiazide diuretic, it has been used in the management of hypertension and oedema.
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Excerpt | Relevance | Reference |
|---|---|---|
| "GYKI 52466 is a benzodiazepine molecule that has muscle relaxant and anticonvulsant properties not attributable to a gamma-aminobutyric acid receptor-mediated mechanism." | 1.29 | A benzodiazepine recognition site associated with the non-NMDA glutamate receptor. ( Olney, JW; Price, MT; Yamada, KA; Zorumski, CF, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zorumski, CF | 1 |
| Yamada, KA | 1 |
| Price, MT | 1 |
| Olney, JW | 1 |
| Strahlendorf, JC | 1 |
| Acosta, S | 1 |
| Strahlendorf, HK | 1 |
2 other studies available for cyclothiazide and Nerve Degeneration
| Article | Year |
|---|---|
A benzodiazepine recognition site associated with the non-NMDA glutamate receptor.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Benzothiadiazines; Binding Sites; Binding, Competitiv | 1993 |
Diazoxide and cyclothiazide convert AMPA-induced dark cell degeneration of Purkinje cells to edematous damage in the cerebellar slice.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Benzothiadiazines; Cerebellum; Di | 1996 |