cyclothiazide has been researched along with Chronic Disease in 1 studies
cyclothiazide: inhibits the desensitization of AMPA-type receptors; structure
cyclothiazide : 3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted at positions 3, 5 and 6 by a 2-norbornen-5-yl group, chlorine, and a sulfonamide group, respectively. A thiazide diuretic, it has been used in the management of hypertension and oedema.
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cyclothiazide (CTZ) has been reported to simultaneously enhance glutamate receptor excitation and inhibit GABAA receptor inhibition, and in turn it evokes epileptiform activities in hippocampal neurons." | 1.40 | Downregulated GABA and BDNF-TrkB pathway in chronic cyclothiazide seizure model. ( Cheng, Z; Kong, S; Liu, J; Wang, Y, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kong, S | 1 |
| Cheng, Z | 1 |
| Liu, J | 1 |
| Wang, Y | 1 |
1 other study available for cyclothiazide and Chronic Disease
| Article | Year |
|---|---|
Downregulated GABA and BDNF-TrkB pathway in chronic cyclothiazide seizure model.
Topics: 4-Aminobutyrate Transaminase; Animals; Behavior, Animal; Benzothiadiazines; Brain-Derived Neurotroph | 2014 |