cyclosporine and Stroke

cyclosporine has been researched along with Stroke in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.00)18.2507
2000's9 (36.00)29.6817
2010's13 (52.00)24.3611
2020's2 (8.00)2.80

Authors

AuthorsStudies
Dimopoulos, C; Kontzoglou, K; Nikiteas, N; Papadakis, M; Perrea, D1
Morshead, CM; Obermeyer, JM; Payne, SL; Shoichet, MS; Siu, RCW; Tuladhar, A; Zand, S1
Forsse, A; Gramsbergen, JB; Nielsen, TH; Nordström, CH; Nygaard, KH; Poulsen, FR1
Amaz, C; Ameli, R; Berner, LP; Berthezene, Y; Cho, TH; Cornut, L; Eker, O; Mewton, N; Nighoghossian, N; Ovize, M1
Azimi, A; Cooke, MJ; Hunt, J; Miu, C; Morshead, CM; Sachewsky, N; Shoichet, MS; Zarin, T1
Ahlehoff, O; Bryld, LE; Gislason, G; Gniadecki, R; Hansen, PR; Iversen, L; Kristensen, SL; Lasthein, S; Lindhardsen, J; Skov, L; Torp-Pedersen, C1
Amarenco, P; Béjot, Y; Berthezène, Y; Bodiguel, E; Cakmak, S; Chauveau, F; Cho, TH; Derex, L; Desal, H; Domigo, V; Giroud, M; Guillon, B; Guiraud, V; Hosseini, H; Jacquin, A; Lamy, C; Mahagne, MH; Mas, JL; Mechtouff, L; Mewton, N; Nighoghossian, N; Ong, E; Oppenheim, C; Ovize, M; Philippeau, F; Rheims, S; Ricolfi, F; Ritzenthaler, T; Sevin-Allouet, M; Sibon, I; Turc, G1
Morshead, CM; Shoichet, MS; Tuladhar, A1
Cho, TH; Mewton, N; Nighoghossian, N; Ong, E; Ovize, M1
Amani, A; Dehpour, AR; Gilani, K; Mehr, SE; Nasoohi, S; Partoazar, A; Rahimi, N; Rezayat, SM1
Simpkins, JW; Yi, KD1
Barba, P; Briones, J; Brunet, S; Delgado, J; Martino, R; Piñana, JL; Querol, L; Sierra, J; Sureda, A; Valcárcel, D1
Liu, RR; Murphy, TH1
Braakman, HM; Lodder, J; Mess, WH; Postma, AA; Span, LF1
Borlongan, CV; Glover, L; Lau, T; Lulic, D; Osman, MM; Stahl, CE; van Loveren, H1
Chang, LT; Chen, YL; Chua, S; Kao, YH; Leu, S; Lin, YC; Shao, PL; Sun, CK; Tsai, TH; Yen, CH; Yip, HK; Yuen, CM1
Azón, A; Gil, I; Grau, C; Hidalgo, I; Martinez, F1
Caicco, MJ; Cooke, MJ; Morshead, CM; Shoichet, MS; Tuladhar, A; Wang, Y1
Heuschling, P; Hodges, H; Male, DK; Modo, M; Patel, S; Rezaie, P1
Borlongan, CV; Carroll, J; Hadman, M; Hess, DC; Irons, H; Lind, JG; Wakade, CG; Yu, G1
Borlongan, CV; Hess, DC; Yu, G1
Kiberd, B; Panek, R1
Goldstein, J; Goyal, M; Mallory, GB; Wong, M; Yamada, KA1
Kelly, JS; Sharkey, J1
Beaudry, F; Marier, JF; Montgomery, J; Ste-Marie, L; Vachon, P1

Reviews

3 review(s) available for cyclosporine and Stroke

ArticleYear
Cyclosporine A, a Potential Therapy of Ischemic Reperfusion Injury. A Common History for Heart and Brain.
    Cerebrovascular diseases (Basel, Switzerland), 2016, Volume: 42, Issue:5-6

    Topics: Animals; Brain; Brain Ischemia; Cyclosporine; Disease Models, Animal; Humans; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Infarction; Myocardial Reperfusion Injury; Neuroprotective Agents; Signal Transduction; Stroke

2016
Cyclosporine-A as a neuroprotective agent against stroke: its translation from laboratory research to clinical application.
    Neuropeptides, 2011, Volume: 45, Issue:6

    Topics: Animals; Brain Injuries; Cell Death; Clinical Trials as Topic; Cyclosporine; Humans; Immunosuppressive Agents; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Molecular Structure; Neuroprotective Agents; Stroke; Treatment Outcome

2011
Immunosuppressants-ligands as neuroprotectants.
    Transplantation proceedings, 2001, Volume: 33, Issue:3

    Topics: Cerebral Infarction; Cyclosporine; Humans; Immunosuppressive Agents; Ligands; Neuroprotective Agents; Stroke; Tacrolimus

2001

Trials

1 trial(s) available for cyclosporine and Stroke

ArticleYear
Cyclosporine in acute ischemic stroke.
    Neurology, 2015, Jun-02, Volume: 84, Issue:22

    Topics: Aged; Aged, 80 and over; Brain Ischemia; Cyclosporine; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Pilot Projects; Single-Blind Method; Stroke; Thrombolytic Therapy

2015

Other Studies

21 other study(ies) available for cyclosporine and Stroke

ArticleYear
The Effect of Cyclosporine and the Consequences in Hepatic and Renal Function Following Ischemic Stroke in a Rats' Model.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2020, Volume: 29, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Brain Ischemia; Cyclosporine; Disease Models, Animal; Kidney; Kidney Diseases; Liver; Liver Diseases; Male; Rats, Wistar; Stroke; Time Factors

2020
Injectable hydrogel enables local and sustained co-delivery to the brain: Two clinically approved biomolecules, cyclosporine and erythropoietin, accelerate functional recovery in rat model of stroke.
    Biomaterials, 2020, Volume: 235

    Topics: Animals; Brain; Cyclosporine; Erythropoietin; Hydrogels; Rats; Stroke

2020
Cyclosporin A ameliorates cerebral oxidative metabolism and infarct size in the endothelin-1 rat model of transient cerebral ischaemia.
    Scientific reports, 2019, 03-06, Volume: 9, Issue:1

    Topics: Animals; Brain Ischemia; Cell Respiration; Cyclosporine; Endothelin-1; Infarction; Ischemic Attack, Transient; Male; Microdialysis; Mitochondria; Oxidative Stress; Rats; Rats, Sprague-Dawley; Stroke

2019
Impact of Collateral Status on Neuroprotective Effect of Cyclosporine A in Acute Ischemic Stroke.
    Current neurovascular research, 2019, Volume: 16, Issue:2

    Topics: Aged; Aged, 80 and over; Brain; Brain Ischemia; Collateral Circulation; Cyclosporine; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuroprotective Agents; Stroke; Treatment Outcome

2019
Cyclosporin A enhances neural precursor cell survival in mice through a calcineurin-independent pathway.
    Disease models & mechanisms, 2014, Volume: 7, Issue:8

    Topics: Animals; bcl-Associated Death Protein; Calcineurin; Cell Count; Cell Survival; Cyclosporine; Male; Mice, Inbred C57BL; Neural Stem Cells; Nitric Oxide Synthase Type I; Recovery of Function; Signal Transduction; Spheroids, Cellular; Stroke; Tacrolimus

2014
Cardiovascular outcomes and systemic anti-inflammatory drugs in patients with severe psoriasis: 5-year follow-up of a Danish nationwide cohort.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2015, Volume: 29, Issue:6

    Topics: Adult; Aged; Anti-Inflammatory Agents; Biological Products; Cardiovascular Diseases; Cause of Death; Climatotherapy; Cyclosporine; Denmark; Dermatologic Agents; Female; Follow-Up Studies; Humans; Incidence; Longitudinal Studies; Male; Methotrexate; Middle Aged; Myocardial Infarction; Phototherapy; Psoriasis; Registries; Retinoids; Severity of Illness Index; Stroke; Tumor Necrosis Factor-alpha; Ustekinumab

2015
Circumventing the blood-brain barrier: Local delivery of cyclosporin A stimulates stem cells in stroke-injured rat brain.
    Journal of controlled release : official journal of the Controlled Release Society, 2015, Oct-10, Volume: 215

    Topics: Animals; Blood-Brain Barrier; Brain Infarction; Cell Count; Cyclosporine; Drug Compounding; Drug Delivery Systems; Hyaluronic Acid; Hydrogels; Immunosuppressive Agents; Lactic Acid; Lateral Ventricles; Male; Methylcellulose; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Long-Evans; Stem Cells; Stroke

2015
Nanoliposome containing cyclosporine A reduced neuroinflammation responses and improved neurological activities in cerebral ischemia/reperfusion in rat.
    Fundamental & clinical pharmacology, 2017, Volume: 31, Issue:2

    Topics: Animals; Brain Ischemia; Cyclosporine; Disease Models, Animal; Infarction, Middle Cerebral Artery; Inflammation; Liposomes; Male; Nanoparticles; Neuroprotective Agents; Peroxidase; Rats; Rats, Wistar; Reperfusion Injury; Stroke; Time Factors; Tumor Necrosis Factor-alpha

2017
Protein phosphatase 1, protein phosphatase 2A, and calcineurin play a role in estrogen-mediated neuroprotection.
    Endocrinology, 2008, Volume: 149, Issue:10

    Topics: Animals; Brain Neoplasms; Calcineurin; Calcineurin Inhibitors; Cell Line, Tumor; Cell Survival; Cyclosporine; Dicarboxylic Acids; Drug Interactions; Enzyme Inhibitors; Estrogens; Glioma; Glutamic Acid; Mice; Neurons; Neuroprotective Agents; Neurotoxins; Okadaic Acid; Oxidative Stress; Protein Phosphatase 1; Protein Phosphatase 2; Rats; Stroke

2008
Early and late neurological complications after reduced-intensity conditioning allogeneic stem cell transplantation.
    Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2009, Volume: 15, Issue:11

    Topics: Adolescent; Adult; Aged; Cerebral Hemorrhage; Cyclosporine; Female; Follow-Up Studies; Graft vs Host Disease; Hematologic Diseases; Humans; Immunosuppressive Agents; Incidence; Kaplan-Meier Estimate; Male; Meningoencephalitis; Middle Aged; Myeloablative Agonists; Nervous System Diseases; Peripheral Blood Stem Cell Transplantation; Peripheral Nervous System Diseases; Postoperative Complications; Recurrence; Retrospective Studies; Risk Factors; Stroke; Time Factors; Transplantation Conditioning; Transplantation, Homologous; Whole-Body Irradiation; Young Adult

2009
Reversible cyclosporin A-sensitive mitochondrial depolarization occurs within minutes of stroke onset in mouse somatosensory cortex in vivo: a two-photon imaging study.
    The Journal of biological chemistry, 2009, Dec-25, Volume: 284, Issue:52

    Topics: Animals; Cell Death; Cyclosporine; Enzyme Inhibitors; Membrane Potential, Mitochondrial; Mice; Mice, Transgenic; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Reperfusion Injury; Somatosensory Cortex; Stroke; Time Factors

2009
Vasospasm is a significant factor in cyclosporine-induced neurotoxicity: case report.
    BMC neurology, 2010, May-11, Volume: 10

    Topics: Antifungal Agents; Cyclosporine; Female; Humans; Magnetic Resonance Imaging; Middle Aged; Neurotoxicity Syndromes; Stroke; Ultrasonography, Doppler, Transcranial; Vasospasm, Intracranial

2010
Combination of cyclosporine and erythropoietin improves brain infarct size and neurological function in rats after ischemic stroke.
    Journal of translational medicine, 2011, Aug-24, Volume: 9

    Topics: Animals; Apoptosis; Aquaporin 4; Brain Infarction; Cell Nucleus; Cyclosporine; Cytochromes c; Drug Therapy, Combination; Erythropoietin; Gene Expression Regulation; Glial Fibrillary Acidic Protein; In Situ Nick-End Labeling; Inflammation; Male; Oxidative Stress; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Rats; Rats, Sprague-Dawley; Recovery of Function; RNA-Binding Proteins; RNA, Messenger; Stroke; Transcription Factors

2011
[Follicular lymphoma with paraneoplastic autoimmune multiorgan syndrome].
    Actas dermo-sifiliograficas, 2012, Volume: 103, Issue:3

    Topics: Aged; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Autoimmune Diseases; Cheilitis; Conjunctivitis; Corneal Ulcer; Cyclophosphamide; Cyclosporine; Diabetes Mellitus, Type 2; Glossitis; Humans; Keratinocytes; Keratosis; Lymphoma, Follicular; Male; Methylprednisolone; Paraneoplastic Syndromes; Pemphigus; Prednisone; Remission Induction; Rituximab; Skin Ulcer; Stroke; Vincristine

2012
A hydrogel composite system for sustained epi-cortical delivery of Cyclosporin A to the brain for treatment of stroke.
    Journal of controlled release : official journal of the Controlled Release Society, 2013, Mar-28, Volume: 166, Issue:3

    Topics: Animals; Brain; Chromatography, Liquid; Cyclosporine; Delayed-Action Preparations; Drug Delivery Systems; Hyaluronic Acid; Hydrogels; Lactic Acid; Methylcellulose; Mice; Mice, Inbred C57BL; Microscopy, Electron, Scanning; Microspheres; Models, Biological; Neural Stem Cells; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Stroke; Surface Properties; Tandem Mass Spectrometry; Time Factors

2013
Transplantation of neural stem cells in a rat model of stroke: assessment of short-term graft survival and acute host immunological response.
    Brain research, 2002, Dec-20, Volume: 958, Issue:1

    Topics: Animals; Biomarkers; Brain Tissue Transplantation; Cell Line, Transformed; Cyclosporine; Disease Models, Animal; Graft Rejection; Graft Survival; Immunohistochemistry; Immunosuppression Therapy; Immunosuppressive Agents; Infarction, Middle Cerebral Artery; Lymphocyte Activation; Neurons; Rats; Rats, Sprague-Dawley; Stem Cell Transplantation; Stroke

2002
Intracerebral xenotransplantation of GFP mouse bone marrow stromal cells in intact and stroke rat brain: graft survival and immunologic response.
    Cell transplantation, 2004, Volume: 13, Issue:3

    Topics: Animals; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Bone Marrow Cells; Bone Marrow Transplantation; Cell Movement; Cell Separation; Cell Survival; Cell Transplantation; Cyclosporine; Flow Cytometry; Green Fluorescent Proteins; Immunosuppressive Agents; Lectins, C-Type; Lymphocytes; Male; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Neurons; Rats; Rats, Sprague-Dawley; Stroke; Time Factors; Transplantation, Heterologous

2004
Combined cyclosporine-A and methylprednisolone treatment exerts partial and transient neuroprotection against ischemic stroke.
    Brain research, 2004, Aug-20, Volume: 1018, Issue:1

    Topics: Animals; Brain Ischemia; Cerebral Infarction; Cyclosporine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Functional Laterality; Infarction, Middle Cerebral Artery; Male; Methylprednisolone; Movement Disorders; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Stroke; Treatment Outcome

2004
Cardiovascular outcomes in the outpatient kidney transplant clinic: the Framingham risk score revisited.
    Clinical journal of the American Society of Nephrology : CJASN, 2008, Volume: 3, Issue:3

    Topics: Adult; Age Factors; Aged; Ambulatory Care Facilities; Cardiovascular Agents; Cyclosporine; Diabetes Complications; Disease-Free Survival; Female; Health Status Indicators; Heart Diseases; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Predictive Value of Tests; Proportional Hazards Models; Prospective Studies; Risk Assessment; Risk Factors; Stroke; Tacrolimus; Time Factors

2008
Neurologic complications of pediatric lung transplantation.
    Neurology, 1999, Oct-22, Volume: 53, Issue:7

    Topics: Adolescent; Adult; Child; Child, Preschool; Cyclosporine; Female; Humans; Hypoxia; Immunosuppressive Agents; Infant; Infant, Newborn; Lung Transplantation; Male; Nervous System Diseases; Prognosis; Pulmonary Circulation; Pulmonary Fibrosis; Retrospective Studies; Risk Factors; Seizures; Stroke; Vascular Diseases

1999
Cyclosporin A in blood and brain tissue following intra-carotid injections in normal and stroke-induced rats.
    Brain research, 2002, Jul-05, Volume: 943, Issue:1

    Topics: Animals; Brain; Carotid Artery, Common; Cyclosporine; Infarction, Middle Cerebral Artery; Injections, Intra-Arterial; Male; Rats; Rats, Sprague-Dawley; Stroke

2002