cyclosporine has been researched along with Reperfusion Injury in 179 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 45 (25.14) | 18.2507 |
| 2000's | 62 (34.64) | 29.6817 |
| 2010's | 62 (34.64) | 24.3611 |
| 2020's | 10 (5.59) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, Y; Huan, M; Ji, Q; Liu, D; Liu, M; Mei, Q; Zhang, B; Zhou, S | 1 |
| Dehpour, AR; Ghasemnejad-Berenji, M; Majdani, R; Yazdani, I | 2 |
| Baetz, D; Bidaux, G; Guebre-Egziabher, F; Juillard, L; Lemoine, S; Pillot, B; Rozes, M; Schleef, M | 1 |
| Gan, G; Huang, Y; Liu, Y; Qu, Y; Tan, Z; Xie, B; Zhou, X; Zhu, J; Zhu, S | 1 |
| Domingues, MAC; Módolo, NSP; Oliveira, ACC; Schwingel, PA | 1 |
| Ning, JZ; Yu, WM; Zhang, DH; Zhou, BZ | 1 |
| Chen, L; Deng, H; Feng, H; Ge, H; Liu, L; Zhang, S | 1 |
| Chai, HT; Chen, CH; Chen, KH; Chiang, JY; Chu, YC; Huang, CR; Sung, PH; Yip, HK | 1 |
| Gui, Q; Jiang, Z; Zhang, L | 1 |
| El Baradie, KBY; Hamrick, MW; Khan, MB; Mendhe, B; O'Brien, F; Waller, J | 1 |
| Jia, LQ; Jiang, XL; Kong, L; Kuang, JS; Lan, ZM; Li, Y; Lv, MJ; Song, N; Tai, H; Wu, J; Xiao, XS; Yang, GL; Yang, P; Yao, SC | 1 |
| Fan, Y; Liu, A; Liu, F; Nicholson, ML; Wang, W; Wu, J; Wu, Y; Yang, B; Yang, C; Zhang, Y; Zhu, T | 1 |
| Carvalho, LR; Castiglia, YM; Deffune, E; Golim, MA; Lemos, SV; Módolo, NS; Nascimento, PD; Souza, AV; Vianna, IG; Vianna, PT | 1 |
| Fang, Q; Li, J; Yan, Z | 1 |
| Bovenkamp, P; Busch, A; Heitplatz, B; Herrmann, KH; Hoerr, V; Kentrup, D; Liu, G; Löffler, B; Pavenstädt, H; Pawelski, H; Reichenbach, JR; Reuter, S; Schlatter, E; Schuette-Nuetgen, K; Van Marck, V; van Zijl, PCM; Yadav, NN | 1 |
| Augeul, L; Baetz, D; Juillard, L; Lemoine, S; Normand, G; Ovize, M; Pillot, B; Rabeyrin, M; Varennes, A | 1 |
| Chae, YJ; Jang, K; Jun, DW; Kang, HT; Lee, JS; Saeed, WK | 1 |
| Atkinson, C; Esckilsen, S; Mehrotra, S; Mulligan, J; Nadig, SN; Tran, DT | 1 |
| Damaskos, C; Daskalopoulou, A; Dimopoulos, C; Garmpis, N; Georgopoulos, S; Kontzoglou, K; Moraitis, S; Nikiteas, N; Papadakis, M; Papaspirou, I; Perrea, D | 1 |
| Argaud, L; Bochaton, T; Cour, M; Jahandiez, V; Monneret, G; Ovize, M; Venet, F | 1 |
| Chen, Y; Dong, W; Dong, Z; Li, C; Li, R; Li, Z; Liang, X; Liu, S; Wang, W; Wu, Y; Yang, H; Ye, Z; Zhang, L; Zhang, M; Zhang, S; Zhao, X | 1 |
| Cheng, CH; Lai, HS; Lai, IR; Lin, HC | 1 |
| Chang, CL; Chen, YT; Cho, CL; Chua, S; Leu, S; Sheu, JJ; Sun, CK; Tsai, TH; Wallace, CG; Yang, CC; Yang, JL; Yip, HK; Zhen, YY | 1 |
| George, AJ; Ma, D; O'Dea, KP; Ologunde, R; Takata, M; Tralau-Stewart, C; Xiao, W; Yoshida, A; Zhao, H | 1 |
| Briot, R; Gennai, S; Pison, C | 1 |
| Fan, Y; Liu, A; Liu, F; Nicholson, ML; Shi, L; Wu, Y; Yang, B; Yang, C; Zhang, J; Zhang, Y; Zhu, T | 1 |
| Dong, Z; Livingston, M; Pallet, N | 1 |
| Aranyi, P; Ferencz, A; Fulop, A; Garbaisz, D; Harsanyi, L; Hermesz, E; Lotz, G; Rosero, O; Szijarto, A; Turoczi, Z | 1 |
| Imura, H; Nitta, T; Shirakawa, M | 1 |
| Li, D; Liu, M; Liu, XH; Shi, DZ; Song, DD; Tao, TQ | 1 |
| Fung, A; Gu, J; Koumpa, FS; Lemaire, A; Lu, K; Ma, D; Ning, J; Sun, JJ; Yi, B; Zhao, H | 1 |
| Ahmed, GO; Farag, MM; Kazem, AH; Shehata, RR | 1 |
| Augeul, L; Juillard, L; Laville, M; Lemoine, S; Ovize, M; Pillot, B; Rayberin, M; Rognant, N; Varennes, A | 1 |
| Hosgood, SA; Lee, G; Nicholson, ML; Patel, MS | 1 |
| Ikemura, K | 1 |
| Briot, R; Gennai, S; Guergour, D; Maignan, M; Schmidt, MH | 1 |
| Chakfe, N; Chamaraux-Tran, TN; Charles, AL; Diemunsch, P; Geny, B; Kemmel, V; Kindo, M; Lejay, A; Pottecher, J; Vogel, T; Zoll, J | 1 |
| Morrissette, KM; Paradis, NA | 1 |
| Becker, LB; Berger, PB | 1 |
| Amani, A; Dehpour, AR; Gilani, K; Mehr, SE; Nasoohi, S; Partoazar, A; Rahimi, N; Rezayat, SM | 1 |
| Ahmadiani, A; Dargahi, L; Fakharnia, F; Khodagholi, F | 1 |
| Algotsson, L; Bjursten, H; Brondén, B; Dardashti, A; Ederoth, P; Elmér, E; Erdling, A; Grins, E; Hansson, MJ; Jovinge, S; Metzsch, C; Mokhtari, A; Nozohoor, S | 1 |
| Atkinson, C; Bailey, SR; Lei, B; Paulos, CM; Tomlinson, S; Zhu, P | 1 |
| Hashimoto, S; Hayashida, S; Honda, M; Inomata, Y; Isono, K; Ohya, Y; Sugawara, Y; Takeichi, T; Yamamoto, H; Yoshii, D | 1 |
| Ashrafpour, H; Cahoon, N; Forrest, CR; Huang, N; Lipa, JE; McAllister, SE; Moses, MA; Neligan, PC; Pang, CY | 1 |
| Cologna, AJ; Lima, LV; Martins, AC; Reis, RB; Rodrigues, AA; Suaid, HJ; Tirapelli, LF; Tucci, S | 1 |
| Calabia, O; Caramelo, C; Castilla, MA; Deudero, JJ; Gonzalez Pacheco, FR; Manzarbeitia, F; Neria, F; Ortiz, A; Sanchez, RF; Tejedor, A | 1 |
| Ikemura, K; Iwamoto, T; Matsuda, H; Mizutani, H; Okuda, M; Urano, K | 1 |
| Abbate, M; Arduini, A; Azzollini, N; Cassis, P; Cugini, D; Gagliardini, E; Noris, M; Peschechera, A; Pezzotta, A; Remuzzi, G | 1 |
| Hayashi, H; Katoh, H; Saotome, M; Satoh, H; Tanaka, T; Urushida, T; Yaguchi, Y | 1 |
| Broekema, M; Harmsen, MC; Koerts, JA; Navis, G; Petersen, AH; Popa, ER; Uges, DR; van Kooten, TG; van Luyn, MJ | 1 |
| Cao, J; Chen, TL; Gui, C; Luo, RH; Shi, H; Wang, JA; Xiang, MX; Xie, XJ; Zhang, X | 1 |
| Devalaraja-Narashimha, K; Diener, AM; Padanilam, BJ | 1 |
| Fujimoto, K; Fukushima, K; Ito, Y; Kokuhu, T; Okamoto, M; Sugioka, N; Takada, K; Tanaka, Y; Yoshimura, N | 1 |
| Hayashi, M; Kishimoto, H; Takizawa, Y; Tomita, M | 1 |
| Liu, RR; Murphy, TH | 1 |
| Andoh, TF; Bennett, WM; Shihab, FS | 1 |
| Yao, H; Yu, JJ | 1 |
| Anglicheau, D; Beaune, P; Bouvier, N; Legendre, C; Pallet, N; Thervet, E | 1 |
| Bobadilla, NA; Bonventre, JV; Collings, FB; Cordier, A; Dieterle, F; Gerhold, D; Goering, PL; Holder, DJ; Marrer, E; Maurer, G; Muniappa, N; Ozer, JS; Perentes, E; Ramirez, V; Sistare, FD; Thudium, D; Troth, S; Vaidya, VS; Vonderscher, J | 1 |
| Burdmann, EA; Castro, I; Malheiros, DM; Pereira, BJ; Yu, L | 1 |
| Feng, L; Li, S; Li, Y; Long, D; Lu, J; Shan, J; Wei, L | 1 |
| Alfarano, C; Bascands, JL; Chaaya, R; Coatrieux, C; Fares, N; Gue, M; Guilbeau-Frugier, C; Kesteman, AS; Parini, A; Schanstra, JP | 1 |
| Dang, K; Feiner, J; Hirose, R; Liu, T; Martinez-Palli, G; Niemann, CU; Serkova, NJ; Xu, F | 1 |
| Chauhan, A; Muthuraman, A; Ramesh, M | 1 |
| Dai, YY; Hao, ML; Ni, SR; Zhu, RW | 1 |
| Dal Canton, A; Esposito, C; Esposito, V; Fasoli, G; Grosjean, F; Mangione, F; Molinaro, M; Rosso, R; Serpieri, N; Sileno, G; Torreggiani, M; Villa, L | 1 |
| Bhavsar, DD; Charakida, M; Deanfield, JE; Loukogeorgakis, SP; MacAllister, RJ; Okorie, MI; Ridout, D | 1 |
| Guo, XS; Hu, WC; Li, YZ; Liu, FY; Liu, XH; Zhang, ZY | 1 |
| Brault, A; Crenesse, D; Huet, PM; Laurens, M; Rocheleau, B; Tarrab, E | 1 |
| Bigam, DL; Cheung, PY; Cho, WJ; Churchill, T; Gill, RS; Lee, TF; Manouchehri, N; Thiesen, A | 1 |
| Braun, M; Langelüddecke, C; Lee, WK; Thévenod, F | 1 |
| Lai, IR; Lee, TK; Lin, HC; Lu, KS; Tsai, CC | 1 |
| Chang, WT; Chen, WJ; Hsu, CY; Huang, CH; Su, YJ; Tsai, MS; Wang, TD | 1 |
| Abe, T; Ichimaru, N; Imamura, R; Isaka, Y; Kakuta, Y; Nonomura, N; Okumi, M; Okuyama, A; Takahara, S; Tsuda, H; Yazawa, K | 1 |
| Alfarano, C; Bascands, JL; Calise, D; Ceccaldi, C; Chaaya, R; Cussac, D; Mias, C; Parini, A; Roubeix, C | 1 |
| Tsoulfas, G | 1 |
| Ashrafpour, H; Cahoon, NJ; Hofer, SO; Huang, N; Lipa, JE; McAllister, SE; Naparus, A; Neligan, PC; Pang, CY; Roy, T; Zhong, T | 1 |
| Inui, M; Shintani-Ishida, K; Yoshida, K | 1 |
| Ikemura, K; Inoue, K; Iwamoto, T; Mizutani, H; Oka, H; Okuda, M | 1 |
| Li, YL; Liu, J; Muelleman, RL; Tran, TP; Tu, H | 1 |
| Allamargot, C; Anderson, ME; Chen, B; Fink, BD; Gao, Z; Hall, DD; He, BJ; Joiner, ML; Koval, OM; Li, J; Luczak, ED; Mohler, PJ; Moore, SA; Scholz, TD; Sivitz, WI; Song, LS; Strack, S; Yang, J | 1 |
| Hasenkam, JM; Moosdorf, R; Nygaard, H; Troitzsch, D; Vogt, S | 1 |
| Belaidi, E; Charles, AL; Diemunsch, P; Geny, B; Gharib, A; Guillot, M; Lejay, A; Pottecher, J | 1 |
| Au-Yeung, KK; O, K; Siow, YL; Wang, G; Zhu, T | 1 |
| Byrne, K; Farr, AL; Krishnadasan, B; Mulligan, MS; Naidu, BV; Rosengart, M; Verrier, ED | 1 |
| Bang, BK; Cha, JH; Choi, BS; Jung, JY; Kim, HW; Kim, J; Kim, WY; Kim, YS; Lee, SH; Li, C; Lim, SW; Yang, CW | 1 |
| Ahmed, A; el-Kossi, M; el-Nahas, M; Haylor, J; Raftery, A | 1 |
| Diaz, FG; O'Regan, MH; Phillis, JW; Pilitsis, JG | 1 |
| Fujisawa, M; Iijima, K; Ishimura, T; Isotani, S; Kamidono, S; Yoshikawa, N | 1 |
| Askar, I; Bozkurt, M | 1 |
| Ahn, HJ; Bang, BK; Choi, BS; Jung, JY; Kim, HW; Kim, J; Kim, WY; Kim, YS; Li, C; Moon, IS; Yang, CW | 1 |
| Kim, JS; Lemasters, JJ; Qian, T | 1 |
| Hirakawa, A; Nakatani, T; Takeyama, N; Tanaka, T | 1 |
| De Broe, ME; De Greef, KE; Kockx, M; Vercauteren, SR; Verhulst, A; Verpooten, GA; Ysebaert, DK | 1 |
| Davis, NA; Inman, SR; Lukaszek, VA; Olson, KM | 1 |
| Davis, NA; Inman, SR; Lukaszek, VA; McKinley, MR; Olson, KM; Seminerio, JL | 1 |
| Tachibana, T | 1 |
| Miyake, H; Nakai, A; Oya, A; Shibazaki, Y; Takeshita, T; Taniuchi, Y | 1 |
| Azizian, M; Bruch, D; Kittur, DS; Ramenaden, ER; Shah, G; Wilasrusmee, C | 1 |
| Lei, XY; Liao, DF; Xu, LP; Yan, FX; Zhou, SG; Zhu, BY | 1 |
| Berens, KL; Dixon, RA; Dupre, B; Feng, L; Han, R; Hancock, WW; Kahan, BD; Kirken, RA; Langer, R; Li, P; Podder, H; Stepkowski, SM; Wang, M | 1 |
| Davis, NA; Inman, SR; Lukaszek, VA; Mazzone, ME; Olson, KM; Yoder, KN | 1 |
| Chander, V; Chopra, K; Singh, D | 1 |
| Bennett, CF; Chen, W; Condon, T; Furian, L; Geary, R; Janczewska, S; Langer, RM; Qu, X; Stecker, K; Stepkowski, SM; Verani, R; Wang, M | 1 |
| Mei, HS; Wang, C; Wang, YL; Zhang, YJ | 1 |
| Büchler, MW; Bunzendahl, H; Klar, E; Kraus, TW; Luntz, SP; Schemmer, P; Seibert-Grafe, M; Unnebrink, K | 1 |
| Ashra, SY; Bowley, L; Imtiaz, S; Jain, S; Nicholson, ML; Pawluczyk, IZ; Yang, B | 1 |
| Plumeyer, F; Reiser, G; Schild, L | 1 |
| Fritz, S; Gebhard, MM; Hackert, T; Hartwig, W; Klar, E; Pfeil, D; Werner, J | 1 |
| Edlich, F; Fischer, G | 1 |
| Kobayashi, E; Murakami, T; Ohsawa, I; Uemoto, S | 1 |
| Weir, MR | 1 |
| Camara, NO; Campanholle, G; Cenedeze, MA; de Paula A Teixeira, V; dos Reis, MA; Galvão-Pereira, M; Pacheco-Silva, A | 1 |
| Câmara, NO; Cenedeze, MA; de Paula, CB; dos Reis, MA; Feitoza, CQ; Gonçalves, GM; Macusso, GD; Pacheco-Silva, A; Pinheiro, HS; Teixeira, Vde P | 1 |
| Chávez, E; Correa, F; Franco, M; García, N; Martínez-Abundis, E; Santamaría, J; Zazueta, C | 1 |
| Antônia dos Reis, M; Câmara, NO; Cenedeze, MA; de Paula Antunes Teixeira, V; de Paula, CB; Feitoza, CQ; Gonçalves, GM; Marques, GD; Pacheco-Silva, A; Pinheiro, HS | 1 |
| Bertocchi, AP; Câmara, NO; Cenedeze, MA; Damião, MJ; Dos Reis, MA; Feitoza, CQ; Gonçalves, GM; Pacheco-Silva, A; Teixeira, VP; Wang, PW | 1 |
| Derumeaux, G; Dumont, JM; Gharib, A; Gomez, L; Ovize, M; Scalfaro, P; Thibault, H; Vuagniaux, G | 1 |
| Currin, RT; Holmuhamedov, E; Lemasters, JJ; Pediaditakis, P; Ramshesh, VK; Theruvath, TP; Tikunov, A; Zhong, Z | 1 |
| Delbridge, MS; El Nahas, AM; Haylor, J; Raftery, AT; Shrestha, BM | 1 |
| Basso, E; Bernardi, P; Colonna, R; costantini, P; Nicolli, A; Petronilli, V | 1 |
| Dhar, DK; Nagasue, N; Nakamura, T; Takemoto, Y; Tsuchiya, M; Uchida, M; Yamanoi, A; Yoshimura, H | 1 |
| Imagawa, DK; Kinkhabwala, M; Martin, P; Melinek, J; Millis, JM; Olthoff, KM; Rudich, S; Seu, P; Shackleton, CR; Stothers, L | 1 |
| Cejalvo, D; Rodriguez, FJ; Suzuki, S; Toledo-Pereyra, LH | 1 |
| Azuma, H; Hancock, WW; Heemann, UW; Pradham, P; Tilney, NL; Tullius, SG | 1 |
| Andersen, HO; Holm, P; Kjeldsen, K; Nordestgaard, BG; Stender, S | 1 |
| Ishii, T; Kai, T; Kim, YI; Kitamura, H; Kobayashi, M; Tatsuma, T | 1 |
| Akizuki, S; Goto, S; Kawano, K; Kim, YI | 1 |
| Gogvadze, V; Richter, C | 1 |
| Hatanaka, N; Inoue, T; Kamiike, W; Matsuda, H; Miyata, M; Nishimura, M; Shimizu, S; Tagawa, K; Yoshida, Y | 1 |
| Goto, S; Kai, T; Kawano, K; Kim, YI; Kobayashi, M; Ono, M | 1 |
| Hardy, KJ; Shulkes, A; Tancheroen, S | 1 |
| Hewitt, CW; Puglisi, RN; Santos, M; Schulte, G; Strande, L; Whalen, TV | 1 |
| Doolin, EJ; Hewitt, CW; Puglisi, RN; Santos, M; Strande, L; Whalen, TV | 1 |
| Codaccioni, MX; Coppin, MC; Hazzan, M; Labalette, M; Lelièvre, G; Noël, C; Pruvot, FR | 1 |
| Bencko, V; Farghali, H; Hynie, S; Kameníková, L | 1 |
| De Broe, ME; De Greef, KE; Eyskens, EJ; Nouwen, EJ; Verpooten, GA; Ysebaert, DK | 1 |
| Herman, B; Lemasters, JJ; Nieminen, AL; Qian, T | 1 |
| McAnulty, JF | 1 |
| Akizuki, E; Ichiguchi, O; Liang, J; Matsuda, T; Matsumura, F; Mori, K; Ogawa, M; Ohshiro, H; Okabe, K; Yamada, S; Yamaguchi, Y | 1 |
| Lemasters, JJ; Nishimura, Y; Romer, LH | 1 |
| Fabia, R; Goldstein, RM; Husberg, BS; Klintmalm, GB; Levy, MF; Netto, GG; Travis, DL | 1 |
| Cetinkale, O; Konukoglu, D; Taşci, I | 1 |
| Bendavid, Y; Buluran, J; Cartier, R; Mathieu, P | 1 |
| Bernardi, P; Di Lisa, F | 1 |
| Arteel, GE; Connor, HD; Frankenberg, MV; Mason, RP; Raleigh, JA; Stachlewitz, RF; Thurman, RG; Yin, M; Zhong, Z | 1 |
| Hatch, GM; Ross, TK | 1 |
| el-Assal, ON; Nagasue, N; Soda, Y; Yu, L | 1 |
| Beato, F; Kato, S; Kusaka, M; Nagano, H; Shaw, GD; Tilney, NL; Zandi-Nejad, K | 1 |
| Ishii, T; Kawano, K; Kim, YI; Kitano, S; Shimada, T; Tatsuma, T | 1 |
| Broelsch, CE; Hertl, M; Hertl, MC; Kluth, D; Kunkel, P; Malagó, M; Prevot, B; Schilling, S | 1 |
| Carlen, PL; Frantseva, MV; Perez Velazquez, JL | 2 |
| Fujimura, A; Hashizume, K; Kanno, T; Kitoh, Y; Kobayashi, E; Miyashita, F; Mizuta, K; Mori, M; Ohmori, M | 1 |
| Bourdel-Marchasson, I; Canioni, P; Delmas-Beauvieux, MC; Diolez, P; Dufour, S; Gallis, JL; Leducq, N | 1 |
| Dragun, D; Haller, H; Hoff, U; Luft, FC; Park, JK; Qun, Y; Schneider, W | 1 |
| Bicknell, GR; Jain, S; Nicholson, ML | 1 |
| He, QP; Li, PA; Siesjö, BK | 1 |
| Bradford, B; Enomoto, N; Ikejema, K; Rose, ML; Rusyn, I; Schemmer, P; Seabra, V; Stacklewitz, RF; Thurman, RG; Wheeler, MD; Yin, M; Zhong, Z | 1 |
| Ishii, T; Kai, T; Kawano, K; Kim, YI; Kobayashi, M; Tatsuma, T | 1 |
| Ghavami, A; Mowlavi, A; Neumeister, M; Song, YH | 1 |
| Ahn, HJ; Bang, BK; Jin, DC; Kim, BS; Kim, J; Kim, YS; Park, JH; Yang, CW | 1 |
| Ahn, HJ; Bang, BK; Han, HJ; Kim, SK; Kim, WY; Kim, YS; Li, C; Moon, IS; Park, JH; Shin, MJ; Yang, CW | 1 |
| Barclay, JL; Clouston, AD; Fawcett, J; Saxton, NE | 1 |
| Geller, DA; Tsoulfas, G | 1 |
| Hou, YY; Lan, W; Liu, GQ; Liu, XD; Pan, GY; Su, Q; Xie, L | 1 |
| Barnes, A; Farr, AL; Krishnadasan, B; Mulligan, MS; Naidu, B; Rosengart, M; Verrier, ED | 1 |
| Bosmans, JL; Chapelle, T; De Broe, ME; De Greef, KE; Roeyen, G; Vercauteren, SR; Verpooten, GA; Ysebaert, DK | 1 |
| Kahan, B; Katz, S; Kerman, R; Lewis, R; Van Buren, C | 1 |
| Akimaru, K; Shouji, T | 1 |
| Kucukcelebi, A; Ozcan, M | 1 |
| Kogure, K; Matsuo, Y; Onodera, H; Shiga, Y | 1 |
| Bennett, WM | 1 |
| Granger, DN; Hunter, J; Kubes, P | 1 |
| Harada, A; Kobayashi, H; Kurokawa, T; Nakao, A; Nonami, T; Ozawa, T; Sugiyama, S; Takagi, H | 1 |
| Heberer, M; Jörgensen, J; Landmann, J; Marx, A; Mihatsch, MJ | 1 |
| Goto, S; Kawano, K; Kim, YI; Kobayashi, M; Shimada, T | 1 |
10 review(s) available for cyclosporine and Reperfusion Injury
| Article | Year |
|---|---|
Insights into the modulatory role of cyclosporine A and its research advances in acute inflammation.
Topics: Acute Disease; Animals; Cyclosporine; Humans; Immunomodulation; Immunosuppressive Agents; Inflammation; Organ Transplantation; Reperfusion Injury; Sepsis; T-Lymphocytes; Wounds and Injuries | 2021 |
Emerging functions of autophagy in kidney transplantation.
Topics: Adaptive Immunity; Autophagy; Cyclosporine; Humans; Immunity, Innate; Immunosuppressive Agents; Kidney; Kidney Transplantation; Reperfusion Injury; Sirolimus | 2014 |
[Molecular Biological Analysis of Factors Influencing Pharmacokinetics to Achieve Personalized Pharmacotherapy].
Topics: Animals; Cimetidine; Cyclosporine; Drug Therapy; Glycoproteins; Humans; Liver; Liver Transplantation; MicroRNAs; Precision Medicine; Rats; Reperfusion Injury; RNA Processing, Post-Transcriptional | 2015 |
[Involvement of endoplasmic reticulum stress in solid organ transplantation].
Topics: Animals; Apoptosis; Cyclosporine; Diabetes Mellitus, Type 2; Drug Delivery Systems; Endoplasmic Reticulum; Graft Survival; Humans; Insulin Resistance; Islets of Langerhans; Kidney Transplantation; Liver Transplantation; Mice; Organ Preservation; Postoperative Complications; Reperfusion Injury; Tacrolimus; Transplantation; Transplantation, Homologous; Unfolded Protein Response | 2010 |
Pharmacological targeting of catalyzed protein folding: the example of peptide bond cis/trans isomerases.
Topics: Animals; Cardiovascular Diseases; Catalysis; Cyclophilins; Cyclosporine; Drug Design; Enzyme Inhibitors; Humans; Immunosuppressive Agents; Inflammation; Neoplasms; NIMA-Interacting Peptidylprolyl Isomerase; Peptidylprolyl Isomerase; Protein Folding; Reperfusion Injury; Skin Diseases; Tacrolimus Binding Protein 1A | 2006 |
Calcium channel blockers in organ transplantation: important new therapeutic modalities.
Topics: Animals; Calcium Channel Blockers; Cyclosporine; Dose-Response Relationship, Drug; Graft Survival; Humans; Immunosuppressive Agents; Kidney; Kidney Transplantation; Models, Biological; Reperfusion Injury; Time Factors | 1990 |
Glycine: a new anti-inflammatory immunonutrient.
Topics: Alcohols; Animals; Anti-Inflammatory Agents; Calcium Channels, L-Type; Chloride Channels; Cyclosporine; Free Radicals; Glycine; Hepatitis, Alcoholic; Humans; Hypoxia; Inflammation; Kupffer Cells; Leukocytes; Melanoma; Reperfusion Injury; Shock, Septic; Taurine | 1999 |
NF-kappaB in transplantation: friend or foe?
Topics: Adenoviridae; Animals; Cyclosporine; Gene Expression Regulation; Genetic Therapy; Graft Rejection; Hepatitis C, Chronic; Humans; Immunosuppressive Agents; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oligodeoxyribonucleotides; Organ Transplantation; Reperfusion Injury; Signal Transduction; Sulfasalazine; Tacrolimus | 2001 |
Mechanisms and amelioration of acute renal allograft failure in the cyclosporine era.
Topics: Acute Kidney Injury; Atrial Natriuretic Factor; Cyclosporine; Diuretics; Glomerular Filtration Rate; Graft Rejection; Humans; Immunosuppression Therapy; Kidney Transplantation; Organ Preservation; Peptide Fragments; Reperfusion Injury | 1992 |
Therapeutic implications of arachidonic acid metabolism in transplant-associated acute renal failure.
Topics: Acute Kidney Injury; Animals; Arachidonic Acid; Cyclosporine; Fatty Acids, Omega-3; Humans; Immunosuppression Therapy; Kidney Transplantation; Lipoxygenase Inhibitors; Prostaglandins, Synthetic; Reperfusion Injury; Thromboxanes | 1992 |
3 trial(s) available for cyclosporine and Reperfusion Injury
| Article | Year |
|---|---|
Cyclosporine A prevents ischemia-reperfusion-induced lymphopenia after out-of-hospital cardiac arrest: A predefined sub-study of the CYRUS trial.
Topics: Aged; Cardiopulmonary Resuscitation; Cyclosporine; Female; Humans; Immunosuppressive Agents; Lymphocyte Count; Lymphopenia; Male; Middle Aged; Out-of-Hospital Cardiac Arrest; Reperfusion Injury; Treatment Outcome | 2019 |
Ciclosporin to Protect Renal function In Cardiac Surgery (CiPRICS): a study protocol for a double-blind, randomised, placebo-controlled, proof-of-concept study.
Topics: Acute Kidney Injury; Biomarkers; Coronary Artery Bypass; Creatinine; Cyclosporine; Double-Blind Method; Glomerular Filtration Rate; Hospitals, University; Humans; Immunosuppressive Agents; Kidney; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Postoperative Complications; Preoperative Care; Proof of Concept Study; Reperfusion Injury; Research Design; Sweden | 2016 |
A randomized controlled trial of pentoxifylline for the prevention of delayed graft function in cadaveric kidney graft.
Topics: Adult; Cadaver; Cyclosporine; Double-Blind Method; Endothelium, Vascular; Female; Humans; Immunosuppressive Agents; Incidence; Ischemia; Kidney; Kidney Transplantation; Macrophage Activation; Macrophages; Neutrophil Activation; Neutrophils; Pentoxifylline; Placebos; Reperfusion Injury; Superoxides; Tumor Necrosis Factor-alpha; Vasoconstrictor Agents; Vasodilator Agents | 1997 |
166 other study(ies) available for cyclosporine and Reperfusion Injury
| Article | Year |
|---|---|
Cyclosporine A loaded brain targeting nanoparticle to treat cerebral ischemia/reperfusion injury in mice.
Topics: Animals; Brain; Brain Ischemia; Cyclosporine; Inflammation; Ischemia; Ischemic Stroke; Mice; Mitochondrial Permeability Transition Pore; Nanoparticles; Reactive Oxygen Species; Reperfusion Injury | 2022 |
Beneficial effects of Cyclosporine A in combination with Nortriptyline on germ cell-specific apoptosis, oxidative stress and epididymal sperm qualities following testicular ischemia/reperfusion in rats: a comparative study.
Topics: Animals; Antioxidants; Apoptosis; Caspase 3; Cyclosporine; Germ Cells; Ischemia; Male; Nortriptyline; Oxidative Stress; Rats; Reperfusion; Reperfusion Injury; Semen; Spermatozoa; Testis | 2022 |
Heat Shock Protein 70 Is Involved in the Efficiency of Preconditioning with Cyclosporine A in Renal Ischemia Reperfusion Injury by Modulating Mitochondrial Functions.
Topics: Animals; Cyclosporine; HSP70 Heat-Shock Proteins; Humans; Hypoxia; Ischemia; Kidney; Mice; Mitochondria; Reperfusion Injury | 2023 |
Cyclosporine A Plus Ischemic Postconditioning Improves Neurological Function in Rats After Cardiac Resuscitation.
Topics: Animals; Apoptosis; Brain; Cardiopulmonary Resuscitation; Cyclosporine; Enzyme Inhibitors; Heart Arrest; Ischemic Postconditioning; Mitochondrial Permeability Transition Pore; Neurons; Post-Cardiac Arrest Syndrome; Rats; Reperfusion Injury | 2020 |
Effects of cyclosporine on ischemia-reperfusion injuries in rat kidneys. An experimental model.
Topics: Animals; Creatinine; Cyclosporine; Disease Models, Animal; Immunosuppressive Agents; Ischemia; Kidney; Male; Rats; Rats, Wistar; Reperfusion Injury; Sodium; Urea | 2019 |
Protective effect of cyclosporine A in the treatment of severe hydronephrosis in a rabbit renal pelvic perfusion model
Topics: Animals; Cyclosporine; Disease Models, Animal; Hydronephrosis; Kidney Pelvis; Rabbits; Random Allocation; Reperfusion Injury; Severity of Illness Index | 2019 |
The effect of cyclosporin a on ischemia-reperfusion damage in a mouse model of ischemic stroke.
Topics: Animals; Behavior, Animal; Blood-Brain Barrier; Brain Ischemia; Cyclosporine; Disease Models, Animal; Ischemic Stroke; Male; Mice, Inbred C57BL; Neuroprotective Agents; Oxidative Stress; Reperfusion Injury | 2020 |
Synergic effect of combined cyclosporin and melatonin protects the brain against acute ischemic reperfusion injury.
Topics: Animals; Apoptosis; Brain; Cell Line, Tumor; Cyclosporine; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Infarction, Middle Cerebral Artery; Melatonin; Mice; Mitochondria; Neurons; Neuroprotective Agents; Oxidative Stress; Rats; Reperfusion Injury | 2021 |
The cyclophilin inhibitor NIM-811 increases muscle cell survival with hypoxia in vitro and improves gait performance following ischemia-reperfusion in vivo.
Topics: Animals; Cell Hypoxia; Cell Survival; Cyclosporine; Female; Humans; Male; Mice; Muscle, Skeletal; Myoblasts, Skeletal; Primary Cell Culture; Reperfusion Injury | 2021 |
Tanshinone IIA combined with CsA inhibit myocardial cell apoptosis induced by renal ischemia-reperfusion injury in obese rats.
Topics: Abietanes; Animals; Apoptosis; Cyclosporine; DNA, Mitochondrial; Heart; Kidney; Male; Membrane Potential, Mitochondrial; Mitochondria, Heart; Mitochondrial Permeability Transition Pore; Myocytes, Cardiac; Obesity; Rats; Reactive Oxygen Species; Reperfusion Injury; Signal Transduction | 2021 |
Long-Term Protection of CHBP Against Combinational Renal Injury Induced by Both Ischemia-Reperfusion and Cyclosporine A in Mice.
Topics: Animals; Apoptosis; Caspase 3; Caspase Inhibitors; Cell Line; Cyclosporine; Disease Models, Animal; Erythropoietin; Kidney; Macrophages; Male; Mice; Mice, Inbred BALB C; Peptide Fragments; Peptides, Cyclic; Reperfusion Injury; RNA, Messenger; RNA, Small Interfering | 2021 |
Cyclosporine A attenuates apoptosis and necrosis after ischemia-reperfusion-induced renal injury in transiently hyperglycemic rats.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Apoptosis; Cell Survival; Cyclosporine; Flow Cytometry; Hyperglycemia; Ischemia; Isoflurane; Kidney; Male; Necrosis; Premedication; Propofol; Protective Agents; Random Allocation; Rats, Wistar; Reperfusion Injury; Reproducibility of Results; Time Factors; Treatment Outcome | 2017 |
A Mechanism Study Underlying the Protective Effects of Cyclosporine-A on Lung Ischemia-Reperfusion Injury.
Topics: Adenine Nucleotide Translocator 1; Animals; Apoptosis; Cyclophilins; Cyclosporine; Cytochromes c; Flow Cytometry; Gene Knockdown Techniques; In Situ Nick-End Labeling; Lung Injury; Membrane Potential, Mitochondrial; Microscopy, Confocal; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Peptidyl-Prolyl Isomerase F; Rabbits; Reperfusion Injury; Voltage-Dependent Anion Channel 1 | 2017 |
GlucoCEST magnetic resonance imaging in vivo may be diagnostic of acute renal allograft rejection.
Topics: Allografts; Animals; CD3 Complex; CD4 Antigens; CD8 Antigens; Contrast Media; Cyclosporine; Disease Models, Animal; Glucose; Graft Rejection; Humans; Kidney; Kidney Transplantation; Magnetic Resonance Imaging; Rats; Rats, Inbred BN; Rats, Inbred Lew; Reperfusion Injury; T-Lymphocytes; Transplantation, Homologous | 2017 |
Dose and timing of injections for effective cyclosporine A pretreatment before renal ischemia reperfusion in mice.
Topics: Acute Kidney Injury; Animals; Calcineurin Inhibitors; Calcium; Calcium Signaling; Cyclosporine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation, Preclinical; Kidney; Male; Mice, Inbred C57BL; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Reperfusion Injury | 2017 |
Does necroptosis have a crucial role in hepatic ischemia-reperfusion injury?
Topics: Animals; Apoptosis; Caspase 3; Cyclosporine; Disease Models, Animal; GTPase-Activating Proteins; Liver; Male; Mice, Inbred C57BL; Necrosis; Receptor-Interacting Protein Serine-Threonine Kinases; Reperfusion Injury | 2017 |
Impact of Mitochondrial Permeability on Endothelial Cell Immunogenicity in Transplantation.
Topics: Animals; CD8-Positive T-Lymphocytes; Cell Line; Coculture Techniques; Cold Ischemia; Cyclosporine; Cytokines; Endothelial Cells; Energy Metabolism; Gene Expression Regulation; Glycolysis; Inflammation Mediators; Lymphocyte Activation; Male; Membrane Potential, Mitochondrial; Mice, Inbred C57BL; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Organ Transplantation; Paracrine Communication; Phenotype; Reperfusion Injury; Warm Ischemia | 2018 |
Expression of S100B Protein in Ischemia/Reperfusion-Induced Brain Injury After Cyclosporine Therapy: A Biochemical Serum Marker with Prognostic Value?
Topics: Animals; Biomarkers; Brain; Brain Injuries; Brain Ischemia; Cerebral Infarction; Cyclosporine; Male; Neuroprotective Agents; Prognosis; Rats; Rats, Wistar; Reperfusion Injury; S100 Calcium Binding Protein beta Subunit | 2019 |
Comparison of multiple doses of cyclosporine A on germ cell apoptosis and epididymal sperm parameters after testicular ischemia/reperfusion in rats.
Topics: Animals; Apoptosis; Caspase 3; Catalase; Cyclosporine; Epididymis; Germ Cells; Glutathione Peroxidase; Immunosuppressive Agents; Male; Malondialdehyde; Oxidative Stress; Rats, Wistar; Reperfusion Injury; Spermatic Cord Torsion; Spermatozoa; Superoxide Dismutase; Testis | 2019 |
p53-cyclophilin D mediates renal tubular cell apoptosis in ischemia-reperfusion-induced acute kidney injury.
Topics: Acute Kidney Injury; Animals; Apoptosis; Cell Line; Cells, Cultured; Cyclosporine; Humans; Kidney Tubules; Male; Peptidyl-Prolyl Isomerase F; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tumor Suppressor Protein p53 | 2019 |
Ischemic postconditioning attenuate reperfusion injury of small intestine: impact of mitochondrial permeability transition.
Topics: Animals; Apoptosis; Atractyloside; Caspase 3; Cyclosporine; Cytochromes c; Disease Models, Animal; Enzyme Activation; Fatty Acid-Binding Proteins; Intestinal Mucosa; Intestine, Small; Ischemic Postconditioning; L-Lactate Dehydrogenase; Ligation; Male; Malondialdehyde; Mesenteric Artery, Superior; Mesenteric Vascular Occlusion; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Oxidative Stress; Rats; Rats, Wistar; Reperfusion Injury; Time Factors | 2013 |
Cyclosporine-assisted adipose-derived mesenchymal stem cell therapy to mitigate acute kidney ischemia-reperfusion injury.
Topics: Acute Kidney Injury; Adipose Tissue; Animals; bcl-2-Associated X Protein; Blood Urea Nitrogen; Caspase 3; Cell- and Tissue-Based Therapy; Creatinine; Cyclosporine; DNA Damage; Kidney; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2013 |
Xenon treatment attenuates early renal allograft injury associated with prolonged hypothermic storage in rats.
Topics: Animals; Cell Line; Cold Temperature; Cyclosporine; Gene Expression Regulation; Genes, MHC Class II; Heme Oxygenase-1; HSP70 Heat-Shock Proteins; Immunosuppressive Agents; Kidney; Kidney Transplantation; Male; NF-kappa B; Rats; Rats, Inbred Lew; Reperfusion Injury; Specimen Handling; Xenon | 2013 |
[Cyclosporine A: from immunomodulation to prevention of ischemia-reperfusion injuries].
Topics: Calcineurin; Calmodulin; Cyclophilin A; Cyclosporine; Humans; Immunosuppressive Agents; Mitochondrial ADP, ATP Translocases; Myocardial Reperfusion Injury; NFATC Transcription Factors; Protein Conformation; Reperfusion Injury | 2013 |
Protective effects of HBSP on ischemia reperfusion and cyclosporine a induced renal injury.
Topics: Acute Kidney Injury; Animals; Apoptosis; Caspase 3; Cyclosporine; Enzyme Activation; Erythropoietin; Fibrosis; Gene Expression; Inflammation; Kidney; Kidney Function Tests; Male; Peptide Fragments; Protective Agents; Rats; Reperfusion Injury; RNA, Messenger | 2013 |
Attenuation of skeletal muscle and renal injury to the lower limb following ischemia-reperfusion using mPTP inhibitor NIM-811.
Topics: Acute Kidney Injury; Animals; Biomarkers; Cell Survival; Cyclosporine; Disease Models, Animal; Hemodynamics; Interleukin-6; Kidney Function Tests; Lower Extremity; Male; Microcirculation; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Muscle Fibers, Skeletal; Rats; Reperfusion Injury; Rhabdomyolysis; Tumor Necrosis Factor-alpha | 2014 |
Propofol protects the immature rabbit heart against ischemia and reperfusion injury: impact on functional recovery and histopathological changes.
Topics: Animals; Cyclosporine; Heart; Hemodynamics; Lactic Acid; Myocardium; Propofol; Protective Agents; Rabbits; Reperfusion Injury | 2014 |
Panax quinquefolium saponin attenuates cardiomyocyte apoptosis and opening of the mitochondrial permeability transition pore in a rat model of ischemia/reperfusion.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cyclosporine; Cytochromes c; Cytosol; Endoplasmic Reticulum Stress; Male; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Reperfusion Injury; Myocytes, Cardiac; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Saponins | 2014 |
Necroptosis and parthanatos are involved in remote lung injury after receiving ischemic renal allografts in rats.
Topics: Acute Lung Injury; Animals; Benzamides; Cells, Cultured; Culture Media, Conditioned; Cyclosporine; DNA Fragmentation; Graft Rejection; Humans; Imidazoles; Immunosuppressive Agents; Indoles; Kidney Transplantation; Kidney Tubules, Proximal; Lung; Male; Necrosis; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Protein Serine-Threonine Kinases; Rats; Rats, Inbred BN; Rats, Inbred Lew; Receptor-Interacting Protein Serine-Threonine Kinases; Reperfusion Injury; Transplantation, Homologous; Tumor Necrosis Factor-alpha | 2015 |
Thymoquinone improves the kidney and liver changes induced by chronic cyclosporine A treatment and acute renal ischaemia/reperfusion in rats.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Benzoquinones; Creatinine; Cyclosporine; Glutathione; Kidney; Liver; Male; Malondialdehyde; Oxidative Stress; Rats; Reperfusion Injury; Superoxide Dismutase; Urea | 2015 |
Postconditioning with cyclosporine a reduces early renal dysfunction by inhibiting mitochondrial permeability transition.
Topics: Animals; Apoptosis; Biomarkers; Creatinine; Cyclosporine; Cytoprotection; Immunosuppressive Agents; Ischemic Postconditioning; Kidney; Kidney Transplantation; Male; Mice, Inbred BALB C; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Models, Animal; Nephrectomy; Oxidative Phosphorylation; Reperfusion Injury; Time Factors; Urea | 2015 |
Hydrogen sulphide as a novel therapy to ameliorate cyclosporine nephrotoxicity.
Topics: Animals; Calcineurin Inhibitors; Cyclosporine; Female; Hydrogen Sulfide; Kidney; Protective Agents; Reperfusion Injury; Swine; Treatment Outcome; Vasoconstriction; Warm Ischemia | 2015 |
Post-conditioning with Cyclosporine A after a 24-hour cold ischemia in ex vivo reperfused pig lungs.
Topics: Animals; Cold Ischemia; Cyclosporine; Ischemic Postconditioning; Lung; Reperfusion Injury; Swine; Time Factors | 2015 |
Skeletal muscle ischemia-reperfusion injury and cyclosporine A in the aging rat.
Topics: Aging; Animals; Cyclosporine; Enzyme Inhibitors; Male; Muscle, Skeletal; Random Allocation; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury | 2016 |
Should reperfusion be revisited?
Topics: Animals; Calcineurin Inhibitors; Cyclosporine; Humans; Hypothermia, Induced; Reperfusion Injury | 2016 |
Cyclosporine for Reperfusion Injury After Cardiac Arrest: Too Little Too Late?
Topics: Cyclosporine; Disease Models, Animal; Heart Arrest; Humans; Myocardial Reperfusion Injury; Reperfusion; Reperfusion Injury | 2016 |
Nanoliposome containing cyclosporine A reduced neuroinflammation responses and improved neurological activities in cerebral ischemia/reperfusion in rat.
Topics: Animals; Brain Ischemia; Cyclosporine; Disease Models, Animal; Infarction, Middle Cerebral Artery; Inflammation; Liposomes; Male; Nanoparticles; Neuroprotective Agents; Peroxidase; Rats; Rats, Wistar; Reperfusion Injury; Stroke; Time Factors; Tumor Necrosis Factor-alpha | 2017 |
Prevention of Cyclophilin D-Mediated mPTP Opening Using Cyclosporine-A Alleviates the Elevation of Necroptosis, Autophagy and Apoptosis-Related Markers Following Global Cerebral Ischemia-Reperfusion.
Topics: Animals; Apoptosis; Autophagy; Cerebral Cortex; Cyclophilins; Cyclosporine; Enzyme Inhibitors; Glutamate Dehydrogenase; Glutamate-Ammonia Ligase; Male; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Peptidyl-Prolyl Isomerase F; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Receptor-Interacting Protein Serine-Threonine Kinases; Reperfusion Injury | 2017 |
Targeted Complement Inhibition Protects Vascularized Composite Allografts From Acute Graft Injury and Prolongs Graft Survival When Combined With Subtherapeutic Cyclosporine A Therapy.
Topics: Animals; Chemotaxis, Leukocyte; Complement Activation; Complement C3; Complement Inactivating Agents; Composite Tissue Allografts; Cyclosporine; Genotype; Graft Survival; Hindlimb; Immunosuppressive Agents; Male; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Models, Animal; Phenotype; Receptor, Anaphylatoxin C5a; Receptors, G-Protein-Coupled; Recombinant Fusion Proteins; Reperfusion Injury; Spleen; T-Lymphocytes; Time Factors; Vascularized Composite Allotransplantation | 2017 |
Intravital Imaging of Neutrophil Recruitment Reveals the Efficacy of FPR1 Blockade in Hepatic Ischemia-Reperfusion Injury.
Topics: Animals; Apoptosis; Chemokines; Chemotaxis, Leukocyte; Cyclosporine; Cytokines; Intravital Microscopy; Liver; Male; Mice; Monocytes; Necrosis; Neutrophil Infiltration; Neutrophils; Receptors, Formyl Peptide; Reperfusion Injury | 2017 |
Postconditioning for salvage of ischemic skeletal muscle from reperfusion injury: efficacy and mechanism.
Topics: Adenosine Triphosphate; Animals; Atractyloside; Calcium; Cyclosporine; Disease Models, Animal; Infarction; Injections, Intravenous; Mitochondria, Muscle; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Muscle, Skeletal; Peroxidase; Reperfusion Injury; Swine; Time Factors | 2008 |
Cyclosporine action on kidneys of rats submitted to normothermic ischaemia and reperfusion.
Topics: Animals; Biomarkers; Creatinine; Cyclosporine; Disease Models, Animal; Immunosuppressive Agents; Ischemia; Kidney; Male; Nephrectomy; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Time Factors; Urea | 2008 |
Inhibition of JAK2 protects renal endothelial and epithelial cells from oxidative stress and cyclosporin A toxicity.
Topics: Animals; Cyclosporine; Endothelial Cells; Epithelial Cells; Janus Kinase 2; Kidney; Mice; Oxidative Stress; Protective Agents; Reperfusion Injury; Tyrphostins | 2009 |
Decreased oral absorption of cyclosporine A after liver ischemia-reperfusion injury in rats: the contribution of CYP3A and P-glycoprotein to the first-pass metabolism in intestinal epithelial cells.
Topics: Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile; Biological Availability; Cyclosporine; Cytochrome P-450 CYP3A; Hydroxylation; Immunosuppressive Agents; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Ketoconazole; Liver Circulation; Liver Transplantation; Male; Microsomes; Microsomes, Liver; Postoperative Complications; Rats; Rats, Wistar; Reperfusion Injury; Testosterone | 2009 |
Propionyl-L-carnitine prevents early graft dysfunction in allogeneic rat kidney transplantation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carnitine; Cyclosporine; Graft Survival; Kidney Cortex Necrosis; Kidney Transplantation; Neutrophil Infiltration; Protective Agents; Rats; Reperfusion Injury; Transplantation, Homologous | 2008 |
Transient opening of mitochondrial permeability transition pore by reactive oxygen species protects myocardium from ischemia-reperfusion injury.
Topics: Animals; Calcium; Cyclosporine; Fluoresceins; Hydrogen Peroxide; Magnetic Resonance Spectroscopy; Male; Membrane Potential, Mitochondrial; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Ventricular Function, Left | 2009 |
Ciclosporin does not influence bone marrow-derived cell differentiation to myofibroblasts early after renal ischemia/reperfusion.
Topics: Actins; Animals; Bone Marrow; Cell Differentiation; Cyclosporine; Enzyme Inhibitors; Fibroblasts; Humans; Ischemia; Kidney; Male; Muscle, Smooth; Rats; Rats, Inbred F344; Reperfusion Injury; Stem Cells | 2009 |
Cyclosporin A pre-incubation attenuates hypoxia/reoxygenation-induced apoptosis in mesenchymal stem cells.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; bcl-Associated Death Protein; Cell Survival; Cyclosporine; Cytochromes c; Enzyme Activation; Hypoxia; Male; Membrane Potential, Mitochondrial; Mesenchymal Stem Cells; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NFATC Transcription Factors; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2008 |
Cyclophilin D gene ablation protects mice from ischemic renal injury.
Topics: Adenosine Triphosphate; Animals; Blood Urea Nitrogen; Creatinine; Cyclophilins; Cyclosporine; Disease Models, Animal; Epithelial Cells; Hydrogen Peroxide; Kidney; L-Lactate Dehydrogenase; LLC-PK1 Cells; Membrane Potential, Mitochondrial; Mice; Mice, Knockout; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Necrosis; Neutrophil Infiltration; Oxidants; Oxidative Stress; Peptidyl-Prolyl Isomerase F; Reperfusion Injury; Swine; Time Factors | 2009 |
Comparison of pharmacokinetics of cyclosporine A in cadaveric and living-related renal transplant recipients and in an experimental rat model of renal failure.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Animals; Area Under Curve; Child; Cyclosporine; Cytochrome P-450 CYP3A; Disease Models, Animal; Drug Monitoring; Duodenum; Female; Graft Rejection; Humans; Immunosuppressive Agents; Injections, Intravenous; Intestinal Absorption; Kidney Transplantation; Living Donors; Male; Midazolam; Middle Aged; Rats; Rats, Wistar; Renal Insufficiency; Reperfusion Injury; Retrospective Studies; Substrate Specificity; Young Adult | 2009 |
Effects of intestinal ischemia/reperfusion on P-glycoprotein mediated biliary and renal excretion of rhodamine123 in rat.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biliary Tract; Cimetidine; Cyclosporine; Kidney; Liver; Male; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Reperfusion Injury; Rhodamine 123; Tetraethylammonium; Verapamil | 2009 |
Reversible cyclosporin A-sensitive mitochondrial depolarization occurs within minutes of stroke onset in mouse somatosensory cortex in vivo: a two-photon imaging study.
Topics: Animals; Cell Death; Cyclosporine; Enzyme Inhibitors; Membrane Potential, Mitochondrial; Mice; Mice, Transgenic; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Reperfusion Injury; Somatosensory Cortex; Stroke; Time Factors | 2009 |
Role of cellular cholesterol in pharmacologic preconditioning with cyclosporine in experimental kidney transplantation.
Topics: Animals; Anticholesteremic Agents; Cholesterol; Cyclosporine; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Immunosuppressive Agents; Indoles; Kidney; Kidney Cortex; Kidney Transplantation; Male; Rats; Rats, Inbred F344; Reperfusion Injury; Time Factors; Transplantation Conditioning | 2010 |
[Dynamic changes of serum MCP-1 and MIP-2 chemokines after renal transplantation in rats].
Topics: Animals; Chemokine CCL2; Chemokine CXCL2; Cyclosporine; Graft Rejection; Kidney Transplantation; Male; Postoperative Period; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reperfusion Injury | 2009 |
Kidney injury molecule-1 outperforms traditional biomarkers of kidney injury in preclinical biomarker qualification studies.
Topics: Acetylglucosaminidase; Animals; Biomarkers, Pharmacological; Blood Urea Nitrogen; Cell Adhesion Molecules; Cisplatin; Creatinine; Cyclosporine; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Gentamicins; Histocytochemistry; Kidney; Kidney Function Tests; Male; Oligonucleotide Array Sequence Analysis; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reperfusion Injury; ROC Curve; Thioacetamide | 2010 |
Effects of sirolimus alone or in combination with cyclosporine A on renal ischemia/reperfusion injury.
Topics: Animals; Cyclosporine; Drug Therapy, Combination; Glomerular Filtration Rate; Immunosuppressive Agents; Kidney; Kidney Tubules, Proximal; Male; Nephrectomy; Rats; Rats, Wistar; Reperfusion Injury; Sirolimus | 2010 |
HIF-1alpha accumulation upregulates MICA and MICB expression on human cardiomyocytes and enhances NK cell cytotoxicity during hypoxia-reoxygenation.
Topics: Adenoviridae; Cell Hypoxia; Cell Line, Tumor; Cyclosporine; Heart Transplantation; Histocompatibility Antigens Class I; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunosuppressive Agents; Killer Cells, Natural; Myocytes, Cardiac; Oxygen; Reperfusion Injury; RNA Interference; Time Factors; Up-Regulation | 2010 |
Pargyline reduces renal damage associated with ischaemia-reperfusion and cyclosporin.
Topics: Animals; Cyclosporine; Disease Models, Animal; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Monoamine Oxidase Inhibitors; Oxidative Stress; Pargyline; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury | 2011 |
Donor pre-treatment with everolimus or cyclosporine does not reduce ischaemia-reperfusion injury in a rat kidney transplant model.
Topics: Animals; Cyclosporine; Everolimus; Graft Rejection; Immunosuppressive Agents; Kidney Function Tests; Kidney Transplantation; Male; Rats; Rats, Inbred Lew; Reperfusion Injury; Sirolimus; Tissue Donors; Transplantation Conditioning; Treatment Outcome | 2011 |
Mitochondrial dependent apoptosis: ameliorative effect of flunarizine on ischemia-reperfusion of celiac artery-induced gastric lesions in the rat.
Topics: Animals; Anti-Ulcer Agents; Apoptosis; Calcium; Celiac Artery; Cyclosporine; Flunarizine; Glutathione; Immunosuppressive Agents; Male; Mitochondria; Omeprazole; Peroxidase; Rats; Rats, Wistar; Reperfusion Injury; Stomach; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Vasodilator Agents | 2011 |
[Effects of cyclosporine A on pneumocyte apoptosis with lung ischemia/reperfusion injury in rats].
Topics: Alveolar Epithelial Cells; Animals; Apoptosis; Caspase 3; Cyclosporine; Cytochromes c; Lung; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2010 |
Sirolimus prevents short-term renal changes induced by ischemia-reperfusion injury in rats.
Topics: Animals; Cyclosporine; Glomerular Filtration Rate; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Function Tests; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sirolimus; Tacrolimus | 2011 |
Postconditioning protects against human endothelial ischaemia-reperfusion injury via subtype-specific KATP channel activation and is mimicked by inhibition of the mitochondrial permeability transition pore.
Topics: Acetylcholine; Adult; Analysis of Variance; Brachial Artery; Cyclosporine; Endothelium, Vascular; Female; Forearm; Glyburide; Humans; Hyperemia; Ischemic Postconditioning; KATP Channels; Ligation; Male; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Reperfusion Injury; Sulfonylurea Compounds; Vascular Resistance; Vasodilation; Vasodilator Agents; Young Adult | 2011 |
Calcineurin mediates the protective effect of postconditioning on skeletal muscle.
Topics: Animals; Animals, Newborn; Apoptosis; Blotting, Western; Calcineurin; Cell Survival; Cells, Cultured; Cyclosporine; Flow Cytometry; Ischemic Preconditioning, Myocardial; Male; Malondialdehyde; Muscle, Skeletal; Rats; Rats, Wistar; Reperfusion Injury | 2011 |
Cyclosporin-A does not prevent cold ischemia/reperfusion injury of rat livers.
Topics: Adenosine; Allopurinol; Animals; Apoptosis; Caspase 3; Cold Ischemia; Cyclosporine; Dimethyl Sulfoxide; Endothelium; Glutathione; Hepatocytes; Insulin; Liver; Liver Transplantation; Male; Models, Animal; Organ Preservation Solutions; Raffinose; Rats; Rats, Inbred Lew; Regional Blood Flow; Reperfusion Injury | 2012 |
Cyclosporine treatment improves mesenteric perfusion and attenuates necrotizing enterocolitis (NEC)-like intestinal injury in asphyxiated newborn piglets during reoxygenation.
Topics: Alberta; Analysis of Variance; Animals; Animals, Newborn; Asphyxia; Cyclosporine; Enterocolitis, Necrotizing; Hemodynamics; Hypoxia; Immunosuppressive Agents; Intestines; Mesenteric Arteries; Oxidative Stress; Random Allocation; Reperfusion Injury; Resuscitation; Swine | 2012 |
Cyclosporin a, but not FK506, induces osmotic lysis of pancreas zymogen granules, intra-acinar enzyme release, and lysosome instability by activating K+ channel.
Topics: Acinar Cells; Amylases; Animals; Biomarkers; Cathepsin B; Cyclosporine; Immunosuppressive Agents; Lysosomes; Male; Osmosis; Pancreas; Pancreas Transplantation; Pancreatitis, Graft; Permeability; Potassium Channels; Rats; Rats, Wistar; Reperfusion Injury; Secretory Vesicles; Tacrolimus | 2012 |
Ischemic postconditioning protects liver from ischemia-reperfusion injury by modulating mitochondrial permeability transition.
Topics: Alanine Transaminase; Animals; Cyclosporine; Cytochromes c; Heme Oxygenase (Decyclizing); Ischemic Postconditioning; Liver; Male; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Oxidative Stress; Rats; Rats, Wistar; Reperfusion Injury | 2012 |
Post-cardiac arrest myocardial dysfunction is improved with cyclosporine treatment at onset of resuscitation but not in the reperfusion phase.
Topics: Animals; Cardiopulmonary Resuscitation; Cyclosporine; Disease Models, Animal; Heart Arrest; Immunosuppressive Agents; Male; Myocardial Contraction; Rats; Rats, Wistar; Reperfusion Injury; Ventricular Dysfunction; Ventricular Function | 2011 |
Carbamylated erythropoietin ameliorates cyclosporine nephropathy without stimulating erythropoiesis.
Topics: Animals; Apoptosis; Collagen Type I; Cyclosporine; Disease Models, Animal; Dogs; Erythropoiesis; Erythropoietin; Fibrosis; Hemoglobins; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Macrophages; Male; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction; Transforming Growth Factor beta1 | 2012 |
Intraparenchymal injection of bone marrow mesenchymal stem cells reduces kidney fibrosis after ischemia-reperfusion in cyclosporine-immunosuppressed rats.
Topics: Adult; Animals; Bone Marrow Cells; Cyclosporine; Disease Models, Animal; Female; Fibrosis; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Middle Aged; Rats; Rats, Inbred Lew; Reperfusion Injury | 2012 |
Cyclosporin-A does not prevent cold ischemia/reperfusion injury of rat livers.
Topics: Animals; Cold Ischemia; Cyclosporine; Liver; Male; Reperfusion Injury | 2012 |
Efficacy and mechanism of hypoxic postconditioning in salvage of ex vivo human rectus abdominis muscle from hypoxia/reoxygenation injury.
Topics: Adenosine Triphosphate; Aged; Cell Survival; Cyclosporine; Female; Humans; Hypoxia; In Vitro Techniques; Ischemic Postconditioning; Middle Aged; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Oxygen; Rectus Abdominis; Reperfusion Injury | 2012 |
Ischemia-reperfusion induces myocardial infarction through mitochondrial Ca²⁺ overload.
Topics: Animals; Apoptosis Inducing Factor; Calcium; Calcium-Binding Proteins; Cyclosporine; Lactones; Male; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Infarction; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Ruthenium Compounds; Sarcoplasmic Reticulum; Spiro Compounds | 2012 |
An antioxidant Trolox restores decreased oral absorption of cyclosporine A after liver ischemia-reperfusion through distinct mechanisms between CYP3A and P-glycoprotein in the small intestine.
Topics: Administration, Oral; Animals; Antioxidants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile Acids and Salts; Chromans; Cyclosporine; Cytochrome P-450 CYP3A; Gene Expression Regulation, Enzymologic; Glutathione; Intestinal Absorption; Intestine, Small; Liver; Male; Malondialdehyde; Rats; Rats, Wistar; Reperfusion Injury; RNA, Messenger; Tissue Distribution | 2012 |
Mitochondria-derived superoxide links to tourniquet-induced apoptosis in mouse skeletal muscle.
Topics: Animals; Antioxidants; Apoptosis; Blotting, Western; Caspase 9; Cyclic N-Oxides; Cyclosporine; Electron Transport Complex IV; Hindlimb; In Situ Nick-End Labeling; Male; Mice; Mice, Inbred C57BL; Mitochondria, Muscle; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Muscle, Skeletal; Reperfusion Injury; Spin Labels; Superoxides; Tourniquets; Ubiquinone; Vitamins | 2012 |
CaMKII determines mitochondrial stress responses in heart.
Topics: Animals; Apoptosis; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cyclosporine; Female; Heart; Heart Failure; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Infarction; Myocardium; Reperfusion Injury; Serine; Stress, Physiological | 2012 |
Effects of cyclosporine pretreatment on tissue oxygen levels and cytochrome oxidase in skeletal muscle ischemia and reperfusion.
Topics: Adenosine Triphosphate; Animals; Constriction; Cyclosporine; Edema; Electron Transport Complex IV; Enzyme Inhibitors; Ischemia; Male; Mitochondria, Muscle; Muscle, Skeletal; Oxygen; Phosphocreatine; Rabbits; Random Allocation; Reperfusion Injury; Tissue Survival | 2013 |
Cyclosporine A normalizes mitochondrial coupling, reactive oxygen species production, and inflammation and partially restores skeletal muscle maximal oxidative capacity in experimental aortic cross-clamping.
Topics: Animals; Aorta; Blotting, Western; Calcium; Constriction; Cyclophilins; Cyclosporine; Disease Models, Animal; Electron Transport Chain Complex Proteins; Energy Metabolism; Immunohistochemistry; Inflammation; Injections, Intraperitoneal; Macrophages; Male; Mitochondria, Heart; Mitochondria, Muscle; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Muscle, Skeletal; Oxidative Stress; Peptidyl-Prolyl Isomerase F; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury; Time Factors | 2013 |
Cyclosporine A protects against apoptosis in ischaemic/reperfused rat kidneys.
Topics: Animals; Apoptosis; Cyclosporine; Ischemia; Kidney; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2002 |
Regulation of chemokine expression by cyclosporine A in alveolar macrophages exposed to hypoxia and reoxygenation.
Topics: Animals; Cell Hypoxia; Chemokines; Cyclosporine; Enzyme-Linked Immunosorbent Assay; Lung; Macrophages, Alveolar; Male; Premedication; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2002 |
Cyclosporine or FK506 decrease mature epidermal growth factor protein expression and renal tubular regeneration in rat kidneys with ischemia/reperfusion injury.
Topics: Animals; Antimetabolites; Bromodeoxyuridine; Cyclosporine; Epidermal Growth Factor; Immunosuppressive Agents; Kidney Tubules; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tacrolimus | 2002 |
Renal warm ischaemic injury in the rat is potentiated by cyclosporine.
Topics: Animals; Cyclosporine; Fibrosis; Immunosuppressive Agents; Kidney; Male; Models, Animal; Rats; Rats, Sprague-Dawley; Renal Circulation; Reperfusion Injury; Temperature | 2002 |
Effects of immunosuppressants, calcineurin inhibition, and blockade of endoplasmic reticulum calcium channels on free fatty acid efflux from the ischemic/reperfused rat cerebral cortex.
Topics: Animals; Calcineurin; Calcineurin Inhibitors; Calcium Channels; Cerebral Cortex; Cyclosporine; Dantrolene; Endoplasmic Reticulum; Enzyme Inhibitors; Fatty Acids, Nonesterified; Gossypol; Immunosuppressive Agents; Macrocyclic Compounds; Male; Oxazoles; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Ryanodine; Sirolimus; Tacrolimus; Thapsigargin; Trifluoperazine | 2002 |
Endothelial nitric oxide synthase expression in ischemia-reperfusion injury after living related-donor renal transplantation.
Topics: Adolescent; Adult; Child; Child, Preschool; Cyclosporine; Family; Female; Follow-Up Studies; Histocompatibility Testing; Humans; Immunohistochemistry; Immunosuppressive Agents; Kidney Transplantation; Living Donors; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Reperfusion Injury; Time Factors; Transplantation, Homologous | 2002 |
Protective effects of immunosuppressants and steroids against ischemia-reperfusion injury in cremaster muscle flap at microcirculatory level.
Topics: Animals; Anti-Inflammatory Agents; Azathioprine; Cyclosporine; Dexamethasone; Disease Models, Animal; Immunosuppressive Agents; Male; Methylprednisolone; Microcirculation; Muscle, Skeletal; Postoperative Complications; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Surgical Flaps | 2002 |
Preconditioning with cyclosporine A or FK506 differentially regulates mitogen-activated protein kinase expression in rat kidneys with ischemia/reperfusion injury.
Topics: Animals; Cyclosporine; Immunosuppressive Agents; Ischemia; Ischemic Preconditioning; JNK Mitogen-Activated Protein Kinases; Kidney; Male; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tacrolimus | 2003 |
Mitochondrial permeability transition in the switch from necrotic to apoptotic cell death in ischemic rat hepatocytes.
Topics: Animals; Apoptosis; Caspase 3; Caspase Inhibitors; Caspases; Cells, Cultured; Cyclosporine; Energy Metabolism; Enzyme Inhibitors; Fructose; Glycine; Glycolysis; Hepatocytes; In Situ Nick-End Labeling; Ischemia; Liver Circulation; Male; Mitochondria, Liver; Necrosis; Permeability; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Staining and Labeling | 2003 |
Mitochondrial permeability transition and cytochrome c release in ischemia-reperfusion injury of the rat liver.
Topics: Animals; Caspase 3; Caspases; Cell Membrane Permeability; Cyclosporine; Cytochrome c Group; Cytosol; DNA Fragmentation; Enzyme Activation; Intracellular Membranes; Liver; Male; Membrane Potentials; Mitochondria, Liver; Rats; Rats, Wistar; Reperfusion Injury; Ruthenium Red | 2003 |
Effect of immunosuppression on damage, leukocyte infiltration, and regeneration after severe warm ischemia/reperfusion renal injury.
Topics: Animals; Cell Division; Cyclosporine; Immunosuppression Therapy; Immunosuppressive Agents; Kidney; Kidney Tubular Necrosis, Acute; Leukocytes; Male; Mycophenolic Acid; Rats; Rats, Inbred Lew; Regeneration; Renal Circulation; Reperfusion Injury; Severity of Illness Index | 2003 |
Simvastatin attenuates renal ischemia/reperfusion injury in rats administered cyclosporine A.
Topics: Analysis of Variance; Animals; Body Weight; Cyclosporine; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Hemodynamics; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunosuppressive Agents; Iohexol; Ischemia; Kidney; Male; Microcirculation; Nitric Oxide; Organ Size; Rats; Rats, Wistar; Reperfusion Injury; Simvastatin; Time Factors; Vasoconstrictor Agents | 2003 |
Rapamycin preserves renal function compared with cyclosporine A after ischemia/reperfusion injury.
Topics: Animals; Calcineurin; Cyclosporine; Glomerular Filtration Rate; Immunosuppressive Agents; Ischemia; Kidney; Kidney Diseases; Kidney Transplantation; Male; Nephrectomy; Postoperative Complications; Rats; Rats, Wistar; Reperfusion Injury; Sirolimus; Tissue and Organ Procurement | 2003 |
[The effects of calcineurin inhibitors on neurologic and histopathologic outcome after transient spinal cord ischemia in rabbits].
Topics: Animals; Apoptosis; Calcineurin Inhibitors; Cyclosporine; Male; Neuroprotective Agents; Rabbits; Reperfusion Injury; Spinal Cord Ischemia; Tacrolimus | 2004 |
Role of mitochondrial permeability transition in fetal brain damage in rats.
Topics: Animals; Apoptosis; Brain Damage, Chronic; Brain Ischemia; Cerebral Cortex; Cyclosporine; Energy Metabolism; Female; Fetal Hypoxia; Ion Channels; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitochondrial Swelling; Pregnancy; Rats; Rats, Wistar; Reperfusion Injury | 2004 |
Augmentation of ischemia/reperfusion injury to endothelial cells by cyclosporin A.
Topics: Analysis of Variance; Animals; Apoptosis; Calcineurin Inhibitors; Cell Count; Cell Line, Transformed; Cell Survival; Cells, Cultured; Coloring Agents; Cyclosporine; Endothelial Cells; Graft Rejection; Immunosuppressive Agents; Ischemia; Mice; Necrosis; Reperfusion Injury; Tacrolimus; Time Factors; Trypan Blue | 2004 |
[Cyclosporin A inhibits the adhesion of neutrophil with ECV-304 induced by hypoxia/reoxygenation via ROS-Cyclophilin A-ERK1/2 pathway].
Topics: Cell Adhesion; Cell Hypoxia; Cells, Cultured; Cyclophilins; Cyclosporine; Endothelium, Vascular; Humans; Intercellular Adhesion Molecule-1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neutrophils; Reactive Oxygen Species; Reperfusion Injury; Signal Transduction; Umbilical Veins | 2004 |
Selectin inhibitor bimosiamose prolongs survival of kidney allografts by reduction in intragraft production of cytokines and chemokines.
Topics: Animals; Chemokines; Cyclosporine; Cytokines; Drug Synergism; Graft Rejection; Graft Survival; Hexanes; Immunosuppressive Agents; Kidney; Kidney Transplantation; Male; Mannose; Rats; Rats, Inbred Strains; Reperfusion Injury; Selectins; Sirolimus | 2004 |
Simvastatin and L-arginine preserve renal function after ischemia/reperfusion injury.
Topics: Animals; Arginine; Cyclosporine; Drug Therapy, Combination; Glomerular Filtration Rate; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunosuppressive Agents; Kidney Diseases; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Simvastatin | 2005 |
Cyclosporine protects against ischemia/reperfusion injury in rat kidneys.
Topics: Animals; Cyclosporine; Immunosuppressive Agents; Injections, Intravenous; Kidney; Kidney Function Tests; Male; Mitochondria; Oxidative Stress; Rats; Rats, Wistar; Reperfusion Injury; Thiobarbituric Acid Reactive Substances | 2005 |
Methoxyethyl-modified intercellular adhesion molecule-1 antisense phosphorothiateoligonucleotides inhibit allograft rejection, ischemic-reperfusion injury, and cyclosporine-induced nephrotoxicity.
Topics: Animals; Cells, Cultured; Cyclosporine; Graft Survival; Humans; Immunosuppressive Agents; Intercellular Adhesion Molecule-1; Kidney; Oligonucleotides, Antisense; Rats; Rats, Inbred ACI; Rats, Inbred Lew; Reperfusion Injury; Thionucleotides; Transplantation, Homologous | 2005 |
Involvement of nuclear factor of activated T-cells (NFATc) in calcineurin-mediated ischemic brain damage in vivo.
Topics: Animals; Brain Ischemia; Calcineurin; Cyclosporine; DNA-Binding Proteins; Fas Ligand Protein; Female; Hippocampus; Membrane Glycoproteins; Neurons; NF-kappa B; NFATC Transcription Factors; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tumor Necrosis Factors | 2005 |
HEGPOL: randomized, placebo controlled, multicenter, double-blind clinical trial to investigate hepatoprotective effects of glycine in the postoperative phase of liver transplantation [ISRCTN69350312].
Topics: Alanine Transaminase; Aspartate Aminotransferases; Clinical Protocols; Cyclosporine; Cytoprotection; Double-Blind Method; Glycine; Glycine Agents; Kidney Diseases; Kupffer Cells; Liver Transplantation; Multicenter Studies as Topic; Postoperative Care; Randomized Controlled Trials as Topic; Reperfusion Injury; Research Design; Survival Rate | 2005 |
Inflammation and caspase activation in long-term renal ischemia/reperfusion injury and immunosuppression in rats.
Topics: Animals; Apoptosis; Caspase 1; Caspase 3; Caspases; Chronic Disease; Cyclosporine; Electrophoresis, Polyacrylamide Gel; Extracellular Matrix; Fibrosis; Glomerulonephritis; Immunosuppressive Agents; Interleukin-1; Male; Mycophenolic Acid; Rats; Rats, Wistar; Reperfusion Injury; Sirolimus; Tacrolimus | 2005 |
Ca(2+) rise within a narrow window of concentration prevents functional injury of mitochondria exposed to hypoxia/reoxygenation by increasing antioxidative defence.
Topics: Animals; Antioxidants; Calcium; Cell Hypoxia; Cell Membrane Permeability; Cell Respiration; Cyclosporine; Cytochrome c Group; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutathione Peroxidase; Male; Membrane Potentials; Mitochondria, Liver; NAD; Oxygen; Oxygen Consumption; Proteins; Rats; Rats, Wistar; Reperfusion Injury; Superoxide Dismutase; Time Factors | 2005 |
Ciclosporin aggravates tissue damage in ischemia reperfusion-induced acute pancreatitis.
Topics: Acute Disease; Animals; Blood Pressure; Cyclosporine; Disease Models, Animal; Heart Rate; Immunosuppressive Agents; Pancreas; Pancreas Transplantation; Pancreatitis; Rats; Reperfusion Injury; Tacrolimus | 2006 |
In vivo luminescent imaging of cyclosporin A-mediated cancer progression in rats.
Topics: Adenocarcinoma; Animals; Benzamides; Blotting, Western; Cell Adhesion; Cell Line, Tumor; Cell Movement; Colonic Neoplasms; Cyclosporine; Dioxoles; Disease Progression; Gene Expression Regulation, Neoplastic; Image Processing, Computer-Assisted; Killer Cells, Natural; Liver Neoplasms; Luminescence; Lymphatic Metastasis; Male; Neoplasm Metastasis; Rats; Rats, Inbred F344; Receptors, Chemokine; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2006 |
Dual response of animals with chronic cyclosporine nephrotoxicity to an acute ischemic injury.
Topics: Animals; Cyclosporine; Disease Models, Animal; Graft Survival; Kidney; Kidney Function Tests; Kidney Transplantation; Male; Rats; Rats, Wistar; Renal Circulation; Reperfusion Injury | 2006 |
Heme oxygenase 1 and renal ischemia and reperfusion injury: the impact of immunosuppressive drug.
Topics: Animals; Creatinine; Cyclosporine; Gene Expression Regulation, Enzymologic; Heme Oxygenase-1; Immunosuppressive Agents; Kidney; Male; Mice; Mice, Inbred C57BL; Protoporphyrins; Reperfusion Injury; Urea | 2006 |
Hypothyroidism provides resistance to kidney mitochondria against the injury induced by renal ischemia-reperfusion.
Topics: Animals; bcl-2-Associated X Protein; Calcium; Cardiolipins; Cyclosporine; Cytochromes c; Disease Models, Animal; Hypothyroidism; Injections, Intraperitoneal; Kidney; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Membranes; Mitochondrial Permeability Transition Pore; NAD; Oxidative Stress; Rats; Reperfusion Injury; Thyroidectomy | 2007 |
The role of immunosuppressive drugs in aggravating renal ischemia and reperfusion injury.
Topics: Animals; Cyclosporine; Immunosuppressive Agents; Kidney Function Tests; Kidney Transplantation; Male; Mice; Mice, Inbred C57BL; Models, Animal; Postoperative Complications; Reperfusion Injury; Sirolimus; Transplantation, Isogeneic; Treatment Outcome | 2007 |
A role for HO-1 in renal function impairment in animals subjected to ischemic and reperfusion injury and treated with immunosuppressive drugs.
Topics: Animals; Cyclosporine; Heme Oxygenase-1; Immunosuppressive Agents; Kidney Diseases; Kidney Function Tests; Male; Mice; Mice, Inbred C57BL; Polymerase Chain Reaction; Reperfusion Injury; Sirolimus; Tacrolimus; Transcription, Genetic | 2007 |
Inhibition of mitochondrial permeability transition improves functional recovery and reduces mortality following acute myocardial infarction in mice.
Topics: Acute Disease; Animals; Calcium; Cyclosporine; Disease Models, Animal; Ischemic Preconditioning, Myocardial; Male; Mice; Mitochondria, Heart; Myocardial Infarction; Permeability; Reperfusion Injury; Survival Analysis; Ventricular Dysfunction, Left | 2007 |
Minocycline and N-methyl-4-isoleucine cyclosporin (NIM811) mitigate storage/reperfusion injury after rat liver transplantation through suppression of the mitochondrial permeability transition.
Topics: Adenosine Diphosphate; Alanine Transaminase; Animals; Anti-Bacterial Agents; Apoptosis; Calcium; Cyclosporine; Graft Survival; Liver; Liver Transplantation; Male; Minocycline; Mitochondria; Mitochondrial Diseases; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Necrosis; Rats; Rats, Inbred Lew; Reperfusion Injury; Tetracycline | 2008 |
FTY720 reduces extracellular matrix expansion associated with ischemia-reperfusion induced injury.
Topics: Animals; Creatinine; Cyclosporine; Disease Models, Animal; Extracellular Matrix; Fingolimod Hydrochloride; Immunosuppressive Agents; Kidney Transplantation; Male; Propylene Glycols; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sphingosine; Transplantation, Homologous | 2007 |
Potential role of cyclosporin A-sensitive mitochondrial channels in ischemia-reperfusion injury.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Cations, Divalent; Cyclosporine; Humans; Intracellular Membranes; Ion Channel Gating; Ion Channels; Membrane Potentials; Mitochondria; Models, Biological; Proton-Translocating ATPases; Reperfusion Injury | 1995 |
Effective prevention of ischemic injury of the dearterialized canine liver by FK506 pretreatment.
Topics: Adenosine Triphosphate; Alanine Transaminase; Animals; Aspartate Aminotransferases; Cyclosporine; Dogs; Female; Ischemia; L-Lactate Dehydrogenase; Liver; Male; Reperfusion Injury; Tacrolimus | 1993 |
Lack of correlation between the magnitude of preservation injury and the incidence of acute rejection, need for OKT3, and conversion to FK506 in cyclosporine-treated primary liver allograft recipients.
Topics: Cyclosporine; Graft Rejection; Graft Survival; Humans; Immunosuppression Therapy; Liver Transplantation; Muromonab-CD3; Organ Preservation; Reperfusion Injury; Retrospective Studies; Tacrolimus | 1995 |
Neutrophil infiltration as an important factor in liver ischemia and reperfusion injury. Modulating effects of FK506 and cyclosporine.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cyclosporine; Ischemia; L-Lactate Dehydrogenase; Liver; Male; Malondialdehyde; Microscopy, Electron; Neutrophils; Peroxidase; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Survival Analysis; Tacrolimus | 1993 |
Antigen-independent events mimic characteristic changes of chronic allograft rejection.
Topics: Animals; Chronic Disease; Cyclosporine; Cytokines; Gene Expression; Graft Rejection; Ischemia; Isoantigens; Kidney Transplantation; Male; Models, Immunological; Rats; Rats, Inbred F344; Rats, Inbred Lew; Reperfusion Injury; T-Lymphocytes; Transplantation, Homologous; Transplantation, Isogeneic | 1995 |
Ischemic injury and experimental transplantation atherosclerosis.
Topics: Animals; Aorta, Abdominal; Aorta, Thoracic; Arteriosclerosis; Cholesterol; Cyclosporine; Ischemia; Rabbits; Reperfusion Injury; Transplantation, Homologous; Vascular Surgical Procedures | 1994 |
Attenuation of cold ischemic liver injury by cyclosporine in association with endotoxemia and chemokine release.
Topics: Animals; Cold Temperature; Cyclosporine; Endotoxins; Graft Survival; Ischemia; Kinetics; Liver; Liver Circulation; Liver Transplantation; Male; Organ Preservation; Rats; Rats, Wistar; Reperfusion Injury; Time Factors; Tumor Necrosis Factor-alpha | 1994 |
Intrahepatic neutrophil accumulation in ischemia/reperfusion injury of pig liver.
Topics: Animals; Biopsy; Cyclosporine; Female; Ischemia; Liver; Liver Circulation; Male; Neutrophils; Reference Values; Regional Blood Flow; Reperfusion Injury; Swine | 1994 |
Cyclosporine A protects mitochondria in an in vitro model of hypoxia/reperfusion injury.
Topics: Adenosine Diphosphate; Animals; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cyclosporine; Egtazic Acid; Hypoxia; Kinetics; Mitochondria, Liver; Oxygen Consumption; Rats; Reperfusion Injury | 1993 |
Enzyme release from mitochondria during reoxygenation of rat liver.
Topics: Animals; Aspartate Aminotransferases; Calcium; Cyclosporine; Cytosol; Liver; Mitochondria, Liver; Permeability; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 1994 |
Evidence that both cyclosporin and azathioprine prevent warm ischemia reperfusion injury to the rat liver.
Topics: Administration, Oral; Alanine Transaminase; Animals; Aspartate Aminotransferases; Azathioprine; Cyclosporine; Electron Spin Resonance Spectroscopy; Female; Lipid Peroxidation; Liver; Malondialdehyde; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Spin Labels; Superoxide Dismutase | 1993 |
Premedication with cyclosporine and perindopril modifies the ischaemia-reperfusion injury during liver resection in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bilirubin; Body Weight; Cyclosporine; Hepatectomy; Immunosuppressive Agents; Indoles; Liver; Liver Function Tests; Male; Organ Size; Perindopril; Premedication; Prothrombin Time; Rats; Rats, Wistar; Reperfusion Injury | 1996 |
Beneficial effects of cyclosporine and rapamycin in small bowel ischemic injury.
Topics: alpha-Glucosidases; Animals; Cyclosporine; Immunosuppressive Agents; Intestinal Mucosa; Intestine, Small; Ischemia; Male; Polyenes; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sirolimus; Tumor Necrosis Factor-alpha; Xanthine Oxidase | 1996 |
The effect of cyclosporine in gut ischemic injury: a computerized morphometric and enzymatic analysis.
Topics: alpha-Glucosidases; Animals; Cyclosporine; Disease Models, Animal; Enterocolitis, Pseudomembranous; Image Interpretation, Computer-Assisted; Immunosuppressive Agents; Intestinal Mucosa; Intestine, Small; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Xanthine Oxidase | 1996 |
Response of immobilized hepatocytes in a perfusion system to anoxia/reoxygenation: effect of cyclosporine A pretreatment.
Topics: Animals; Cell Hypoxia; Cell Membrane; Cells, Cultured; Cells, Immobilized; Cyclosporine; Immunosuppressive Agents; L-Lactate Dehydrogenase; Liver; Male; Perfusion; Rats; Rats, Wistar; Reperfusion Injury; Urea | 1996 |
Influence of cyclosporin A on the damage and regeneration of the kidney after severe ischemia/reperfusion injury.
Topics: Animals; Cyclosporine; Immunosuppressive Agents; Kidney; Male; Rats; Rats, Inbred Lew; Regeneration; Reperfusion Injury | 1997 |
Mitochondrial permeability transition in pH-dependent reperfusion injury to rat hepatocytes.
Topics: Adenosine Triphosphate; Aerobiosis; Anaerobiosis; Animals; Cell Death; Cell Survival; Cells, Cultured; Cyclosporine; Glycine; Hydrogen-Ion Concentration; Liver; Male; Mitochondria, Liver; Permeability; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Time Factors | 1997 |
The effect of calcium on hypothermia-facilitated resuscitation of warm ischemic kidney tissue slices: a role for the mitochondrial permeability transition pore?
Topics: Adenosine Triphosphate; Aerobiosis; Animals; Calcium; Cold Temperature; Cyclosporine; Fatty Acids, Nonesterified; In Vitro Techniques; Ischemia; Kidney Cortex; Kidney Transplantation; Male; Mitochondria; Permeability; Quinacrine; Rabbits; Reperfusion Injury; Solutions; Tissue Preservation | 1998 |
Immunosuppressants decrease neutrophil chemoattractant and attenuate ischemia/reperfusion injury of the liver in rats.
Topics: Animals; Azathioprine; Cyclosporine; Drug Evaluation, Preclinical; Immunosuppressive Agents; Interleukin-16; Liver; Male; Neutrophils; Polyenes; Rats; Rats, Wistar; Reperfusion Injury; Sirolimus; Tacrolimus; Time Factors | 1998 |
Mitochondrial dysfunction and cytoskeletal disruption during chemical hypoxia to cultured rat hepatic sinusoidal endothelial cells: the pH paradox and cytoprotection by glucose, acidotic pH, and glycine.
Topics: Adenosine Triphosphate; Animals; Cell Hypoxia; Cells, Cultured; Cyclosporine; Cytoprotection; Cytoskeleton; Endothelium, Vascular; Glucose; Glycine; Hydrogen-Ion Concentration; Male; Membrane Potentials; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 1998 |
Protection by cyclosporine A against normothermic liver ischemia-reperfusion in pigs.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cyclosporine; Dose-Response Relationship, Drug; Hepatic Artery; Immunosuppressive Agents; Ischemia; Liver; Liver Circulation; Reference Values; Regional Blood Flow; Reperfusion Injury; Temperature | 1998 |
Effects of cyclosporin A and ibuprofen on liver ischemia-reperfusion injury in the rat.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspartate Aminotransferases; Cyclooxygenase Inhibitors; Cyclosporine; Ibuprofen; Immunosuppressive Agents; Ischemia; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 1998 |
[Cyclosporine A prevents ischemia-reperfusion induced myocardial dysfunction in the isolated heart of the rat].
Topics: Animals; Coronary Artery Bypass; Cyclosporine; Disease Models, Animal; Follow-Up Studies; Hemodynamics; Immunosuppressive Agents; Models, Biological; Oxygen Consumption; Prognosis; Rats; Reperfusion Injury; Ventricular Dysfunction | 1997 |
Mitochondrial function as a determinant of recovery or death in cell response to injury.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Calcium; Cell Membrane Permeability; Cells, Cultured; Cyclosporine; Heart; Ion Channels; Ischemia; Mitochondria; Myocardium; Oxidative Phosphorylation; Reperfusion Injury | 1998 |
Cyclosporin A increases hypoxia and free radical production in rat kidneys: prevention by dietary glycine.
Topics: Animals; Creatinine; Cyclosporine; Food, Fortified; Free Radicals; Glomerular Filtration Rate; Glycine; Hypoxia; Kidney; Male; Models, Biological; Nitroimidazoles; Rats; Rats, Sprague-Dawley; Renal Circulation; Reperfusion Injury; Time Factors; Vasoconstriction | 1998 |
Cyclosporin A does not affect cardiolipin biosynthesis during ischemia-reperfusion injury in the heart.
Topics: Animals; Cardiolipins; Cyclosporine; Male; Mitochondria, Heart; Myocardium; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 1998 |
Suppressed endothelin-1 production by FK506 and cyclosporin A in ischemia/reperfusion of rat small intestine.
Topics: Animals; Azepines; Blood Pressure; Cyclosporine; Endothelin Receptor Antagonists; Endothelin-1; Hypotension; Immunosuppressive Agents; Intestine, Small; Ischemia; Male; Microcirculation; Oligopeptides; Portal System; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptors, Endothelin; Reperfusion Injury; Survival Rate; Tacrolimus; Time Factors | 1999 |
Exploitation of the continuum between early ischemia/reperfusion injury and host alloresponsiveness: indefinite kidney allograft survival by treatment with a soluble P-selectin ligand and low-dose cyclosporine in combination.
Topics: Animals; Chemokine CCL2; Cyclosporine; Dose-Response Relationship, Immunologic; Drug Therapy, Combination; Graft Survival; Immunohistochemistry; Immunosuppressive Agents; Intercellular Adhesion Molecule-1; Ischemia; Isoantibodies; Kidney; Kidney Transplantation; Male; Membrane Glycoproteins; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Messenger | 1999 |
Amelioration of tumor necrosis factor release by cyclosporine in warm ischemia/reperfusion injury of the rat liver: with special reference to hepatic ultrastructure.
Topics: Animals; Cyclosporine; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Immunosuppressive Agents; Liver; Microscopy, Electron; Rats; Rats, Sprague-Dawley; Reference Values; Reperfusion Injury; Survival Rate; Transaminases; Tumor Necrosis Factor-alpha | 1999 |
Tauroursodeoxycholate ameliorates reperfusion injury after pig liver transplantation.
Topics: Animals; Cholagogues and Choleretics; Cyclosporine; Immunosuppressive Agents; Liver; Liver Function Tests; Liver Transplantation; Male; Postoperative Complications; Reperfusion Injury; Swine; Taurochenodeoxycholic Acid | 1999 |
Molecular mechanisms of free radical production and protective efficacies of antioxidants in in vitro ischemia-reperfusion.
Topics: Animals; Antioxidants; Cyclosporine; Free Radicals; Glutathione; Hippocampus; Niacinamide; Organ Culture Techniques; Pyramidal Cells; Rats; Reperfusion Injury; Vitamin E | 1999 |
Effect of pretreatment with FTY720 and cyclosporin on ischaemia-reperfusion injury of the liver in rats.
Topics: Animals; Cyclosporine; Fingolimod Hydrochloride; Immunosuppressive Agents; Leukocyte Count; Leukocytes, Mononuclear; Liver; Male; Neutrophil Activation; Peroxidase; Propylene Glycols; Rats; Rats, Wistar; Reperfusion Injury; Sphingosine; Transaminases; Tumor Necrosis Factor-alpha | 1999 |
Mitochondrial and energetic dysfunctions of the liver during normothermic reperfusion: protective effect of cyclosporine and role of the mitochondrial permeability transition pore.
Topics: Adenosine Triphosphate; Animals; Cyclosporine; Energy Metabolism; Intracellular Membranes; Liver; Mitochondria, Liver; Rats; Reperfusion; Reperfusion Injury | 2000 |
Ischemia-reperfusion injury in renal transplantation is independent of the immunologic background.
Topics: Animals; Cell Adhesion Molecules; Cyclosporine; Graft Rejection; Immunosuppressive Agents; Integrin alpha4beta1; Integrins; Ischemia; Kidney; Kidney Transplantation; Lymphocyte Function-Associated Antigen-1; Male; Necrosis; Nephritis; Rats; Rats, Inbred F344; Rats, Inbred Lew; Receptors, Lymphocyte Homing; Renal Circulation; Reperfusion Injury; Selectins; Transplantation, Homologous; Transplantation, Isogeneic | 2000 |
Tacrolimus has less fibrogenic potential than cyclosporin A in a model of renal ischaemia-reperfusion injury.
Topics: Animals; Creatinine; Cyclosporine; Fibrosis; Gene Expression; Immunosuppressive Agents; Kidney Diseases; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Proteinuria; Rats; Rats, Wistar; Renal Artery; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; Tacrolimus; Transforming Growth Factor beta | 2000 |
Effects of intracarotid arterial injection of cyclosporin A and spontaneous hypothermia on brain damage incurred after a long period of global ischemia.
Topics: Animals; Blood Glucose; Brain Infarction; Brain Ischemia; Cardiovascular Physiological Phenomena; Carotid Arteries; Cyclosporine; Hypothermia, Induced; Immunosuppressive Agents; Injections, Intra-Arterial; Male; Neuroprotective Agents; Rats; Rats, Wistar; Reperfusion Injury; Respiratory Physiological Phenomena; Survival Rate; Time Factors | 2001 |
Immunodepressants ameliorate normothermic ischemia injury to the rat liver by down-regulating tumor necrosis factor, not by alleviation of lipid peroxidative injury.
Topics: Alanine Transaminase; Animals; Azathioprine; Cyclosporine; Female; Immunosuppressive Agents; Ischemia; Lipid Peroxidation; Liver; Phosphatidylcholines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tacrolimus; Temperature; Time Factors; Tumor Necrosis Factor-alpha | 1994 |
Limited use of cyclosporin A in skeletal muscle ischemia--reperfusion injury.
Topics: Animals; Cyclosporine; Edema; Hindlimb; Immunosuppressive Agents; Male; Muscle, Skeletal; Rats; Rats, Wistar; Reperfusion Injury; Surgical Flaps; Tissue Survival | 2001 |
Preconditioning with sodium arsenite inhibits apoptotic cell death in rat kidney with ischemia/reperfusion or cyclosporine-induced Injuries. The possible role of heat-shock protein 70 as a mediator of ischemic tolerance.
Topics: Animals; Apoptosis; Arsenites; Caspases; Cyclosporine; DNA Fragmentation; Gene Expression; HSP70 Heat-Shock Proteins; In Situ Nick-End Labeling; Ischemic Preconditioning; Kidney; Kidney Diseases; Kidney Tubular Necrosis, Acute; Male; Microscopy, Electron; Mitochondria; Rats; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Messenger; Sodium Compounds | 2001 |
Dynamics of intracellular calcium and free radical production during ischemia in pyramidal neurons.
Topics: Aniline Compounds; Animals; Brain Ischemia; Calcium; Calcium Channels; Calcium-Binding Proteins; Culture Techniques; Cyclosporine; Electron Transport Complex I; Fluorescent Dyes; Free Radicals; Heterocyclic Compounds, 3-Ring; Hippocampus; Intracellular Fluid; Mitochondria; NADH, NADPH Oxidoreductases; Niacinamide; Pyramidal Cells; Rats; Rats, Wistar; Reperfusion Injury; Rhodamines; Rotenone; Ruthenium Compounds; Xanthenes | 2001 |
Pharmacological preconditioning with low-dose cyclosporine or FK506 reduces subsequent ischemia/reperfusion injury in rat kidney.
Topics: Animals; Apoptosis; Blood Urea Nitrogen; Caspases; Creatinine; Cyclosporine; Dose-Response Relationship, Drug; Gene Expression; HSP70 Heat-Shock Proteins; Immunosuppressive Agents; Interleukin-1; Ischemia; Kidney Transplantation; Male; Rats; Rats, Sprague-Dawley; Renal Circulation; Reperfusion Injury; Tacrolimus; Transplantation Conditioning; Tumor Necrosis Factor-alpha | 2001 |
Cyclosporin A pretreatment in a rat model of warm ischaemia/reperfusion injury.
Topics: Animals; Apoptosis; Cyclosporine; Disease Models, Animal; Hot Temperature; Immunosuppressive Agents; In Situ Nick-End Labeling; Liver; Male; Microscopy, Electron; Neutrophils; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2002 |
Cyclosporin A enhanced protection of nimodipine against brain damage induced by hypoxia-ischemia in mice and rats.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain Ischemia; Calcium Channel Blockers; Cerebral Cortex; Cyclosporine; L-Lactate Dehydrogenase; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Neuroprotective Agents; Nimodipine; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2002 |
Decreased lung ischemia-reperfusion injury in rats after preoperative administration of cyclosporine and tacrolimus.
Topics: Animals; Bronchoalveolar Lavage Fluid; Capillary Permeability; Cyclosporine; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Electrophoretic Mobility Shift Assay; Immunosuppressive Agents; Leukocytes; Lung; Male; NF-kappa B; Peroxidase; Preoperative Care; Rats; Rats, Long-Evans; Reperfusion Injury; RNA, Messenger; Tacrolimus; Treatment Outcome | 2002 |
Effect of immunosuppression on damage, leukocyte infiltration, and regeneration after severe warm ischemia/reperfusion renal injury.
Topics: Animals; Cell Division; Cyclosporine; Immunosuppressive Agents; Kidney; Kidney Transplantation; Leukocytes; Mycophenolic Acid; Neutrophils; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred Lew; Regeneration; Reperfusion Injury | 2002 |
[Pathology of the grafted liver].
Topics: Azathioprine; Cyclosporine; Graft Rejection; Hepatitis, Viral, Human; Humans; Liver; Liver Transplantation; Organ Preservation; Reperfusion Injury | 1992 |
The beneficial effect of cyclosporin-A on the no-reflow phenomenon in rat skin island flaps.
Topics: Animals; Cyclosporine; Graft Survival; Male; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Reperfusion Injury; Skin; Surgical Flaps | 1992 |
Cyclosporin A protects against ischemia-reperfusion injury in the brain.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Urea Nitrogen; Brain Edema; Brain Injuries; Cerebral Arteries; Cyclosporine; Male; Rats; Rats, Wistar; Reperfusion Injury | 1992 |
Effects of cyclosporin A and FK506 on ischemia/reperfusion-induced neutrophil infiltration in the cat.
Topics: Animals; Cats; Cyclosporine; In Vitro Techniques; Intestine, Small; Ischemia; Leukocyte Count; Leukotriene B4; Neutrophils; Peroxidase; Reperfusion Injury; Tacrolimus | 1991 |
Beneficial effects of cyclosporine on postischemic liver injury in rats.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Alanine Transaminase; Animals; Aspartate Aminotransferases; Cyclosporine; Hepatic Veins; L-Lactate Dehydrogenase; Liver; Male; Mitochondria, Liver; Rats; Rats, Inbred Strains; Regional Blood Flow; Reperfusion Injury | 1992 |
Protective effect of allopurinol and superoxide dismutase in renal isografts in cyclosporin A-treated rats.
Topics: Allopurinol; Animals; Cyclosporine; Free Radical Scavengers; Immunosuppression Therapy; Kidney Transplantation; Kidney Tubular Necrosis, Acute; Male; Rats; Rats, Inbred WF; Reperfusion Injury; Superoxide Dismutase | 1991 |
The effects of pretransplant cyclosporine therapy on rats grafted with twelve-hour cold-stored livers--with special reference to reperfusion injury.
Topics: Animals; Cold Temperature; Cyclosporine; Graft Survival; Liver; Liver Transplantation; Male; Malondialdehyde; Organ Preservation; Rats; Rats, Inbred Strains; Reperfusion Injury; Time Factors | 1991 |