cyclosporine and Parkinson Disease

cyclosporine has been researched along with Parkinson Disease in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (33.33)18.2507
2000's7 (29.17)29.6817
2010's6 (25.00)24.3611
2020's3 (12.50)2.80

Authors

AuthorsStudies
Agrawal, BK; Chakrabarti, S; Chakrabarti, SS; Chandan, G; Ganguly, U; Pal, S; Saini, RV; Singh, S; Thakur, R1
Chen, G; He, Q; Li, PA; Zhang, M1
Andreas, LB; Baker, JD; Becker, S; Blair, LJ; Favretto, F; Flores, D; Strohäker, T; Zweckstetter, M1
Cappai, R; Chakrabarti, S; Ganguly, A; Ganguly, G; Ganguly, U; Sahoo, A; Sen, O1
Chang, CY; Chen, S; Hsieh, W; Lin, SZ; Wang, Y; Wang, YC; Yang, CS; Yu, SJ1
Cai, H; Ding, J; Lin, X; Liu, G; Luo, J; Parisiadou, L; Sun, L; Xie, C; Yu, J1
Agrawal, S; Dixit, A; Patel, DK; Singh, A; Singh, D; Singh, MP; Tripathi, P1
Bergstrand, S; Björklund, A; Churchill, MJ; Colino-Sanguino, Y; Decressac, M; Herz, NJ; Ippolito, R; Meshul, CK; Sconce, MD; Tamburrino, A; Wan, OW; Wolf, DA1
Barron, A; Caldwell, GA; Caldwell, KA; Galiano, F; Lee, YJ; Patel, D; Wang, S; Witt, SN; Xu, C; Zhang, S1
Hirabayashi, H; Ishizaka, S; Matsuda, R; Nakase, H; Nishimura, F; Nonaka, J; Ouji, Y; Sakaki, T; Toriumi, H; Yamada, S; Yoshikawa, M1
Bartus, RT; Borlongan, CV; Emerich, DF; Hoffer, BJ1
Barker, RA; Harrower, TP; Hooks, Y; Tyers, P1
Ansari, AA; Breeze, RE; Freed, CR; Hutchinson, M; Kriek, EH; Mayne, A; Mazziotta, JC; O'Brien, CF; Schneck, SA; Zhang, YB1
Earl, CD; Kupsch, A; Oertel, WH; Sautter, J1
Burns, LH; Deacon, TW; Dinsmore, J; Galpern, WR; Isacson, O1
Borlongan, CV; Cahill, DW; Cameron, DF; Freeman, TB; Sanberg, PR; Saporta, S; Stahl, CE1
Borlongan, CV; Cahill, DW; Freeman, TB; Hauser, RA; Sanberg, PR1
Cooper, JM; Schapira, AH; Seaton, TA1
Berman, SB; Hastings, TG1
Honey, CR; Levy, JG; Margaron, P; Obochi, MO; Shen, H; Yip, S1
Ambrosio, S; Ferrer, I; Gil, J; Gómez, C; Piqué, M; Reiriz, J1
Brown, AM; Burke, WJ; Conway, AD; Jain, JC; Kristal, BS; Li, SW; Ulluci, PA1
Dawson, TM; Engelender, S; Igarashi, S; L Dawson, V; Rao, RK; Ross, CA; Sawa, A; Tanaka, Y; Tanzi, RE; Wanner, T1
Bunney, BS; Gjedde, A; Leranth, C; Marek, KL; Naftolin, F; Price, LH; Robbins, RJ; Roth, RH; Spencer, DD; Vollmer, T1

Reviews

3 review(s) available for cyclosporine and Parkinson Disease

ArticleYear
NanoCsA improves the survival of human iPSC transplant in hemiparkinsonian rats.
    Brain research, 2019, 09-15, Volume: 1719

    Topics: Animals; Cell Differentiation; Corpus Striatum; Cyclosporine; Disease Models, Animal; Graft Survival; Humans; Induced Pluripotent Stem Cells; Male; Nanoparticles; Neurons; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Stem Cell Transplantation; Transplantation, Heterologous

2019
[Neuronal transplantation in animal models of Parkinson disease: in vivo voltammetry, tissue cryopreservation and immunology].
    Zentralblatt fur Neurochirurgie, 1995, Volume: 56, Issue:4

    Topics: Animals; Brain Tissue Transplantation; Cryopreservation; Cyclosporine; Disease Models, Animal; Dopamine; Fetal Tissue Transplantation; Graft Rejection; Humans; Immunosuppressive Agents; Mesencephalon; Parkinson Disease; Parkinson Disease, Secondary; Rats

1995
CNS immunological modulation of neural graft rejection and survival.
    Neurological research, 1996, Volume: 18, Issue:4

    Topics: Adrenal Medulla; Adult; Animals; Antibodies, Monoclonal; Brain; Brain Tissue Transplantation; Cell Transplantation; Cyclosporine; Dopamine; Drug Compounding; Fetal Tissue Transplantation; Genetic Therapy; Genetic Vectors; Graft Rejection; Graft Survival; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Male; Mesencephalon; Mice; Parkinson Disease; Primates; Rats; Sertoli Cells; Transplantation, Heterologous; Transplantation, Heterotopic; Tyrosine 3-Monooxygenase

1996

Trials

3 trial(s) available for cyclosporine and Parkinson Disease

ArticleYear
Lack of a detectable systemic humoral/cellular allogeneic response in human and nonhuman primate recipients of embryonic mesencephalic allografts for the therapy of Parkinson's disease.
    Transplantation proceedings, 1995, Volume: 27, Issue:1

    Topics: Animals; Antibody Formation; Antibody-Dependent Cell Cytotoxicity; Brain Tissue Transplantation; Cell Line; Cyclosporine; Cytotoxicity, Immunologic; Fetal Tissue Transplantation; Follow-Up Studies; Humans; Immunity, Cellular; Levodopa; Lymph Nodes; Mesencephalon; Parkinson Disease; Prednisone; Primates; Spleen; T-Lymphocytes, Cytotoxic; Time Factors; Transplantation, Homologous

1995
Cyclosporine-A increases locomotor activity in rats with 6-hydroxydopamine-induced hemiparkinsonism: relevance to neural transplantation.
    Surgical neurology, 1996, Volume: 46, Issue:4

    Topics: Animals; Brain; Cyclosporine; Dextroamphetamine; Dopamine Agonists; Immunosuppressive Agents; Locomotion; Male; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Tissue Transplantation

1996
Unilateral transplantation of human fetal mesencephalic tissue into the caudate nucleus of patients with Parkinson's disease.
    The New England journal of medicine, 1992, Nov-26, Volume: 327, Issue:22

    Topics: Activities of Daily Living; Adult; Antiparkinson Agents; Caudate Nucleus; Cryopreservation; Cyclosporine; Dopamine; Female; Fetal Tissue Transplantation; Homovanillic Acid; Humans; Magnetic Resonance Imaging; Male; Mesencephalon; Middle Aged; Motor Activity; Parkinson Disease; Putamen; Stereotaxic Techniques; Tomography, Emission-Computed

1992

Other Studies

18 other study(ies) available for cyclosporine and Parkinson Disease

ArticleYear
Protective effects of cyclosporine A on neurodegeneration and motor impairment in rotenone-induced experimental models of Parkinson's disease.
    European journal of pharmacology, 2022, Aug-15, Volume: 929

    Topics: Animals; Cyclosporine; Humans; Models, Theoretical; Motor Disorders; Neuroblastoma; Neuroprotective Agents; Parkinson Disease; Rats; Rats, Wistar; Rotenone

2022
Suppression of NLRP3 Inflammasome, Pyroptosis, and Cell Death by NIM811 in Rotenone-Exposed Cells as an in vitro Model of Parkinson's Disease.
    Neuro-degenerative diseases, 2020, Volume: 20, Issue:2-3

    Topics: Animals; Caspase 1; Cell Death; Cell Survival; Cyclosporine; Humans; Inflammasomes; Interleukin-1beta; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; Parkinson Disease; Pyroptosis; Reactive Oxygen Species; Rotenone; Signal Transduction

2020
Catalysis of proline isomerization and molecular chaperone activity in a tug-of-war.
    Nature communications, 2020, 11-27, Volume: 11, Issue:1

    Topics: alpha-Synuclein; Amyloid; Catalysis; Cyclophilin A; Cyclosporine; Humans; Isomerism; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Chaperones; Parkinson Disease; Proline; Protein Aggregates; Protein Binding; Protein Domains

2020
Dopamine Cytotoxicity on SH-SY5Y Cells: Involvement of α-Synuclein and Relevance in the Neurodegeneration of Sporadic Parkinson's Disease.
    Neurotoxicity research, 2019, Volume: 35, Issue:4

    Topics: alpha-Synuclein; Cell Line, Tumor; Cell Survival; Cyclosporine; Dopamine; Humans; Membrane Potential, Mitochondrial; Parkinson Disease

2019
A calcineurin- and NFAT-dependent pathway is involved in α-synuclein-induced degeneration of midbrain dopaminergic neurons.
    Human molecular genetics, 2014, Dec-15, Volume: 23, Issue:24

    Topics: alpha-Synuclein; Animals; Apoptosis; Calcineurin; Calcineurin Inhibitors; Cyclosporine; Dopaminergic Neurons; Gene Expression Regulation; HEK293 Cells; Humans; Mesencephalon; Mice; Mice, Transgenic; Mutation; NFATC Transcription Factors; Parkinson Disease; Primary Cell Culture; Signal Transduction

2014
Cyclosporine A and MnTMPyP Alleviate α-Synuclein Expression and Aggregation in Cypermethrin-Induced Parkinsonism.
    Molecular neurobiology, 2015, Volume: 52, Issue:3

    Topics: alpha-Synuclein; Animals; Corpus Striatum; Cyclosporine; Dopaminergic Neurons; Metalloporphyrins; Mitochondria; Oxidative Stress; Parkinson Disease; Parkinsonian Disorders; Pyrethrins; Rats, Wistar; Substantia Nigra

2015
Cyclosporin promotes neurorestoration and cell replacement therapy in pre-clinical models of Parkinson's disease.
    Acta neuropathologica communications, 2015, Dec-14, Volume: 3

    Topics: alpha-Synuclein; Animals; Cell Transplantation; Cells, Cultured; Cognition Disorders; Cyclosporine; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Enzyme Inhibitors; Female; Humans; Mesencephalon; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Nerve Tissue Proteins; Neurons; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Time Factors; Tyrosine 3-Monooxygenase

2015
Chemical Compensation of Mitochondrial Phospholipid Depletion in Yeast and Animal Models of Parkinson's Disease.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: alpha-Synuclein; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Carboxy-Lyases; Cyclosporine; Disease Models, Animal; Dopaminergic Neurons; Endoplasmic Reticulum Stress; Meclofenoxate; Membrane Proteins; Mitochondria; Mitochondrial Proteins; Parkinson Disease; Phosphatidylcholines; Phosphatidylethanolamines; Protective Agents; Saccharomyces cerevisiae; Solubility; Sulfaphenazole; Transferases (Other Substituted Phosphate Groups)

2016
Treatment of Parkinson's disease model mice with allogeneic embryonic stem cells: necessity of immunosuppressive treatment for sustained improvement.
    Neurological research, 2009, Volume: 31, Issue:3

    Topics: Animals; Apomorphine; Corpus Striatum; Cyclosporine; Disease Models, Animal; Embryonic Stem Cells; Immunosuppressive Agents; Lymphocyte Activation; Male; Mice; Mice, Inbred Strains; Motor Activity; Oxidopamine; Parkinson Disease; Stem Cell Transplantation; Time Factors; Transplantation, Homologous; Tyrosine 3-Monooxygenase

2009
Bradykinin receptor agonist facilitates low-dose cyclosporine-A protection against 6-hydroxydopamine neurotoxicity.
    Brain research, 2002, Nov-29, Volume: 956, Issue:2

    Topics: Adrenergic Agents; Animals; Behavior, Animal; Blood-Brain Barrier; Bradykinin; Calcineurin; Corpus Striatum; Cyclosporine; Disease Models, Animal; Drug Synergism; Immunohistochemistry; Male; Motor Activity; Neuroprotective Agents; Oxidopamine; Parkinson Disease; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Receptors, Bradykinin; Substantia Nigra; Tyrosine 3-Monooxygenase

2002
Long-term survival and integration of porcine expanded neural precursor cell grafts in a rat model of Parkinson's disease.
    Experimental neurology, 2006, Volume: 197, Issue:1

    Topics: Animals; Brain; CD8 Antigens; Cell Differentiation; Cyclosporine; Ectodysplasins; Embryo, Mammalian; Female; Graft Rejection; Immunosuppressive Agents; Membrane Proteins; Myelin Sheath; Nerve Fibers; Neurons; Oxidopamine; Parkinson Disease; Pregnancy; Rats; Rats, Sprague-Dawley; Stem Cell Transplantation; Stereotyped Behavior; Swine; Sympathectomy, Chemical; Sympatholytics; Synapses; Transplantation, Heterologous; Tumor Necrosis Factors; Tyrosine 3-Monooxygenase

2006
Xenotransplantation of porcine fetal ventral mesencephalon in a rat model of Parkinson's disease: functional recovery and graft morphology.
    Experimental neurology, 1996, Volume: 140, Issue:1

    Topics: Animals; Brain Tissue Transplantation; Cyclosporine; Disease Models, Animal; Female; Mesencephalon; Parkinson Disease; Rats; Rats, Sprague-Dawley; Swine; Time Factors; Transplantation, Heterologous

1996
Cyclosporin inhibition of apoptosis induced by mitochondrial complex I toxins.
    Brain research, 1998, Oct-26, Volume: 809, Issue:1

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Coloring Agents; Cyclosporine; Dopamine Agents; Enzyme Inhibitors; Fluorescein-5-isothiocyanate; Fluorescent Dyes; In Situ Nick-End Labeling; Intracellular Membranes; Mitochondria; NAD(P)H Dehydrogenase (Quinone); Oxidative Stress; Parkinson Disease; PC12 Cells; Propidium; Rats; Rotenone; Uncoupling Agents

1998
Dopamine oxidation alters mitochondrial respiration and induces permeability transition in brain mitochondria: implications for Parkinson's disease.
    Journal of neurochemistry, 1999, Volume: 73, Issue:3

    Topics: Animals; Brain; Cell Membrane Permeability; Cyclosporine; Dopamine; In Vitro Techniques; Male; Mitochondria; Mitochondria, Liver; Mitochondrial Swelling; Monoamine Oxidase; Monophenol Monooxygenase; Oxidation-Reduction; Oxygen Consumption; Parkinson Disease; Rats; Rats, Sprague-Dawley

1999
Reduced xenograft rejection in rat striatum after pretransplant photodynamic therapy of murine neural xenografts.
    Journal of neurosurgery, 2000, Volume: 92, Issue:1

    Topics: Analysis of Variance; Animals; Brain Tissue Transplantation; Corpus Striatum; Cyclosporine; Dopamine; Graft Rejection; Graft Survival; Immunosuppressive Agents; Male; Mice; Parkinson Disease; Photochemotherapy; Photosensitizing Agents; Porphyrins; Rats; Rats, Wistar; Transplantation, Heterologous; Verteporfin

2000
Low concentrations of 1-methyl-4-phenylpyridinium ion induce caspase-mediated apoptosis in human SH-SY5Y neuroblastoma cells.
    Journal of neuroscience research, 2001, Mar-01, Volume: 63, Issue:5

    Topics: 1-Methyl-4-phenylpyridinium; Amino Acid Chloromethyl Ketones; Apoptosis; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cyclosporine; Cysteine Proteinase Inhibitors; Cytochrome c Group; DNA Fragmentation; Dose-Response Relationship, Drug; Fas Ligand Protein; fas Receptor; Humans; Membrane Glycoproteins; Membrane Potentials; Mitochondria; Neoplasm Proteins; Nerve Tissue Proteins; Neuroblastoma; Oligopeptides; Osmolar Concentration; Parkinson Disease; Tumor Cells, Cultured

2001
Selective dopaminergic vulnerability: 3,4-dihydroxyphenylacetaldehyde targets mitochondria.
    Free radical biology & medicine, 2001, Apr-15, Volume: 30, Issue:8

    Topics: 3,4-Dihydroxyphenylacetic Acid; 4-Aminobenzoic Acid; Aminobenzoates; Animals; Aristolochic Acids; Cell Death; Cell Differentiation; Cyclosporine; Dopamine; Dopamine Antagonists; Enzyme Inhibitors; Ion Channels; Male; Membrane Proteins; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Nerve Growth Factor; para-Aminobenzoates; Parkinson Disease; PC12 Cells; Phenanthrenes; Rats; Rats, Inbred F344; Respiration; Rotenone; Trifluoperazine; Uncoupling Agents

2001
Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis.
    Human molecular genetics, 2001, Apr-15, Volume: 10, Issue:9

    Topics: Acetylcysteine; alpha-Synuclein; Animals; Apoptosis; Blotting, Western; Caspase 3; Caspase 9; Caspases; Cyclosporine; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Gene Expression Regulation; Immunoenzyme Techniques; Membrane Potentials; Mitochondria; Multienzyme Complexes; Mutation; Nerve Tissue Proteins; Parkinson Disease; PC12 Cells; Proteasome Endopeptidase Complex; Rats; Synucleins; Tetracycline; Transfection

2001