cyclosporine and Nerve Degeneration

cyclosporine has been researched along with Nerve Degeneration in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (25.00)18.2507
2000's12 (75.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ichikawa, Y; Igarashi, O; Ikeda, K; Iwamoto, K; Iwasaki, Y; Kinoshitata, M1
Adamchik, Y; Carlen, PL; Frantseva, M; Perez Velazquez, JL; Tonkikh, A1
Bennett, JP; Dennis, J; Jenkins, R; Keeney, PM; Kindler, DD; Kostecki, V; Solenski, NJ; Thiffault, C1
Diaz-Ruiz, A; Guizar-Sahagún, G; Ibarra, A; Perez-Severiano, F; Ríos, C; Segovia, J; Vergara, P1
Au, WY; Ho, SL; Kwong, YL; Leung, SY; Mak, W1
Blumbergs, PC; Donkin, JJ; Finnie, JW; Jones, NR; Koszyca, B; Kuchel, T; Manavis, J; Reilly, PL; Van Den Heuvel, C; Vink, R1
Craddock, SD; Korde, AS; Maragos, WF; Pettigrew, LC; Pocernich, CB; Waldmeier, PC1
Carlen, PL; Feeney, CJ; Frantseva, MV; Mills, LR; Pennefather, PS; Shniffer, C; Shulyakova, N1
Asanuma, M; Kondo, Y; Ogawa, N1
Kitagawa, K; Mabuchi, T; Matsumoto, M; Matsushita, K; Ohtsuki, T; Taguchi, A; Yagita, Y; Yanagihara, T1
Friberg, H; Halestrap, A; Khaspekov, L; Viktorov, I; Wieloch, T1
Fletcher-Turner, A; Gibson, TR; Hicks, RR; Rabchevsky, AG; Scheff, SW; Sullivan, PG1
Csiszar, K; Elmér, E; Fong, KS; Keep, M1
Isshiki, A; Miyata, K; Omori, N; Shibasaki, F; Uchino, H; Yamaguchi, T1
Baudry, M; Bi, R; Chun, JT; Hoe, W; Liu, R; Liu, W; Schreiber, SS1
Kerr, JF; McCombe, PA; Nguyen, KB; Pender, MP1

Reviews

2 review(s) available for cyclosporine and Nerve Degeneration

ArticleYear
Neurotrauma/neurodegeneration and mitochondrial dysfunction.
    Progress in brain research, 2002, Volume: 137

    Topics: Animals; Brain Injuries; Cell Death; Cyclosporine; Humans; Hypoxia; Ischemia; Mitochondria; Nerve Degeneration; Ruthenium Compounds

2002
[Involvement of immune mechanism in the progressive brain damage].
    Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 1994, Volume: 14, Issue:5

    Topics: Animals; Brain Damage, Chronic; Cyclosporine; Cytokines; Epilepsy; Humans; Movement Disorders; Nerve Degeneration; Neuroglia; Receptors, Muscarinic

1994

Other Studies

14 other study(ies) available for cyclosporine and Nerve Degeneration

ArticleYear
Neuroprotective actions of FK506 and cyclosporin A on motor neuron survival following neonatal axotomy.
    Neurological research, 2002, Volume: 24, Issue:6

    Topics: Animals; Animals, Newborn; Axotomy; Cell Death; Cyclosporine; Dose-Response Relationship, Drug; Motor Neurons; Nerve Degeneration; Neuroprotective Agents; Rats; Sciatic Nerve; Spinal Cord; Tacrolimus

2002
Neurotoxic nitric oxide rapidly depolarizes and permeabilizes mitochondria by dynamically opening the mitochondrial transition pore.
    Molecular and cellular neurosciences, 2003, Volume: 23, Issue:4

    Topics: Animals; bcl-X Protein; Brain Ischemia; Calcium Channels; Calcium-Binding Proteins; Caspase 3; Caspases; Cell Death; Cell Membrane Permeability; Cyclosporine; Dose-Response Relationship, Drug; Fluorescent Dyes; Humans; Intracellular Membranes; Ion Channels; Membrane Potentials; Mitochondria; Nerve Degeneration; Neurons; Nitric Oxide; Proto-Oncogene Proteins c-bcl-2; Rats; Rhodamines; Ruthenium Compounds; Triazenes; Tumor Cells, Cultured

2003
Cyclosporin-A inhibits inducible nitric oxide synthase activity and expression after spinal cord injury in rats.
    Neuroscience letters, 2004, Feb-26, Volume: 357, Issue:1

    Topics: Animals; Cyclosporine; Disease Models, Animal; Female; I-kappa B Proteins; Immunosuppressive Agents; Nerve Degeneration; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Spinal Cord Injuries; Transcription, Genetic

2004
Reversible paraneoplastic neuropathy associated with T-cell large granular lymphocyte leukemia.
    Neurology, 2004, Aug-10, Volume: 63, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biopsy; Cyclosporine; Dexamethasone; Female; Humans; Immunosuppressive Agents; Leukemia, Lymphoid; Male; Middle Aged; Mitoxantrone; Nerve Degeneration; Paraneoplastic Polyneuropathy; Paresthesia; Sural Nerve; T-Lymphocytes; Urinary Retention; Vidarabine

2004
Downregulation of amyloid precursor protein (APP) expression following post-traumatic cyclosporin-A administration.
    Journal of neurotrauma, 2004, Volume: 21, Issue:11

    Topics: Amyloid beta-Protein Precursor; Animals; Brain; Brain Injuries; Cyclosporine; Disease Models, Animal; Down-Regulation; Female; Immunohistochemistry; Injections, Spinal; Nerve Degeneration; Neuroprotective Agents; RNA, Messenger; Sheep; Time Factors; Up-Regulation

2004
Protective effects of NIM811 in transient focal cerebral ischemia suggest involvement of the mitochondrial permeability transition.
    Journal of neurotrauma, 2007, Volume: 24, Issue:5

    Topics: Animals; Brain Infarction; Brain Ischemia; Calcium Signaling; Cell Death; Cyclosporine; Cytochromes c; Disease Models, Animal; Energy Metabolism; Male; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Nerve Degeneration; Neurons; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Inbred SHR; Reactive Oxygen Species; Treatment Outcome

2007
Vulnerability of glial cells to hydrogen peroxide in cultured hippocampal slices.
    Brain research, 2008, Mar-10, Volume: 1198

    Topics: Animals; Animals, Newborn; Antioxidants; Brain Ischemia; Cell Death; Cell Survival; Cells, Cultured; Cyclosporine; Dose-Response Relationship, Drug; Energy Metabolism; Fluorescent Dyes; Free Radicals; Hippocampus; Hydrogen Peroxide; Mitochondrial Membranes; Necrosis; Nerve Degeneration; Neuroglia; Organ Culture Techniques; Oxidative Stress; Pyramidal Cells; Rats; Time Factors

2008
Effect of immunosuppressant FK506 on ischemia-induced degeneration of hippocampal neurons in gerbils.
    Life sciences, 1996, Volume: 59, Issue:19

    Topics: Animals; Body Temperature; Cell Death; Cyclosporine; Female; Gerbillinae; Hippocampus; Immunosuppressive Agents; Ischemic Attack, Transient; Male; Nerve Degeneration; Neuroprotective Agents; Pyramidal Cells; Tacrolimus

1996
Cyclosporin A and its nonimmunosuppressive analogue N-Me-Val-4-cyclosporin A mitigate glucose/oxygen deprivation-induced damage to rat cultured hippocampal neurons.
    The European journal of neuroscience, 1999, Volume: 11, Issue:9

    Topics: Animals; Cell Death; Cell Hypoxia; Cells, Cultured; Cyclophilins; Cyclosporine; Glucose; Hippocampus; Immunophilins; Immunosuppressive Agents; Mice; Mice, Inbred BALB C; Mitochondria; Mitochondrial Swelling; Nerve Degeneration; Neurons; Peptidyl-Prolyl Isomerase F; Rats

1999
Dose-response curve and optimal dosing regimen of cyclosporin A after traumatic brain injury in rats.
    Neuroscience, 2000, Volume: 101, Issue:2

    Topics: Animals; Blood-Brain Barrier; Brain Injuries; Cell Death; Cerebral Cortex; Cyclosporine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Male; Nerve Degeneration; Neuroprotective Agents; Percussion; Rats; Rats, Sprague-Dawley

2000
Intrathecal cyclosporin prolongs survival of late-stage ALS mice.
    Brain research, 2001, Mar-16, Volume: 894, Issue:2

    Topics: Amyotrophic Lateral Sclerosis; Animals; Cyclosporine; Disease Models, Animal; Humans; Immunosuppressive Agents; Injections, Spinal; Mice; Mice, Neurologic Mutants; Mice, Transgenic; Mitochondria; Nerve Degeneration; Superoxide Dismutase; Superoxide Dismutase-1; Survival Rate

2001
Involvement of the brain-derived neurotrophic factor/TrkB pathway in neuroprotecive effect of cyclosporin A in forebrain ischemia.
    Neuroscience, 2001, Volume: 105, Issue:3

    Topics: Animals; Blotting, Western; Brain Ischemia; Brain-Derived Neurotrophic Factor; Cyclic AMP Response Element-Binding Protein; Cyclosporine; Enzyme Inhibitors; Hippocampus; Immunohistochemistry; Male; Nerve Degeneration; Neurons; Neuroprotective Agents; Phosphorylation; Rats; Rats, Wistar; Receptor, trkB; RNA, Messenger; Transcription, Genetic; Up-Regulation

2001
Kainate excitotoxicity in organotypic hippocampal slice cultures: evidence for multiple apoptotic pathways.
    Brain research, 2001, Oct-19, Volume: 916, Issue:1-2

    Topics: Amino Acid Chloromethyl Ketones; Animals; Animals, Newborn; Apoptosis; bcl-2-Associated X Protein; Brain Diseases; Caspase Inhibitors; Caspases; Cells, Cultured; Cyclosporine; Cytochrome c Group; Cytosol; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Hippocampus; Immunohistochemistry; Kainic Acid; Membrane Potentials; Mitochondria; Nerve Degeneration; Neurons; Neuroprotective Agents; Neurotoxins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyramidal Cells; Rats; RNA, Messenger

2001
Apoptosis in the nervous system in experimental allergic encephalomyelitis.
    Journal of the neurological sciences, 1991, Volume: 104, Issue:1

    Topics: Animals; Cyclosporine; Demyelinating Diseases; Encephalomyelitis, Autoimmune, Experimental; Ganglia, Spinal; Immunization, Passive; Inflammation; Meninges; Microscopy, Electron; Myelin Basic Protein; Nerve Degeneration; Rats; Rats, Inbred Strains; Spinal Cord; Spleen

1991