cyclosporine and Necrosis

cyclosporine has been researched along with Necrosis in 155 studies

Research

Studies (155)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's39 (25.16)18.2507
2000's83 (53.55)29.6817
2010's31 (20.00)24.3611
2020's2 (1.29)2.80

Authors

AuthorsStudies
Barbier, M; Boumendjel, A; Boutonnat, J; Hadjeri, M; Mariotte, AM; Ronot, X1
Awais, M; Berry, N; Criddle, DN; Gibson, RR; Javed, MA; Kershaw, NM; Latawiec, D; Lian, LY; O'Neill, PM; Pandalaneni, S; Shore, ER; Sutton, R; Wen, L1
Agrawal, V; Behera, M; Bhadauria, D; Kaul, A; Kushwaha, R; Patel, M; Prasad, N; Shanmugham, S; Srivastava, A; Yaccha, M1
Augeul, L; Baetz, D; Bidaux, G; Chouabe, C; Ferrera, R; Lo-Grasso, M; Védère, M1
Carvalho, LR; Castiglia, YM; Deffune, E; Golim, MA; Lemos, SV; Módolo, NS; Nascimento, PD; Souza, AV; Vianna, IG; Vianna, PT1
Aquila, G; Bonora, M; Campo, G; Ferrari, R; Galluzzi, L; Giorgi, C; Kroemer, G; Lebiedzinska-Arciszewska, M; Morciano, G; Morganti, C; Pedriali, G; Pinton, P; Rizzo, P; Wieckowski, MR1
Chae, YJ; Jang, K; Jun, DW; Kang, HT; Lee, JS; Saeed, WK1
Chen, S; Hu, B; Li, S; Li, Z; Liu, H; Lv, X; Qing, X; Shao, Z; Xu, J; Zhao, L1
Elbayoumi, T; Elgebaly, SA; Kreutzer, DL1
Asano, Y; Bokuda, K; Isozaki, E; Matsubara, S; Miyamoto, K; Morishima, R; Sugaya, K; Tobisawa, S1
Diaz, RJ; Fernandes, K; Harvey, K; Hawrylyshyn, K; Hinek, A; Hossain, T; Lytvyn, Y; Wilson, GJ1
Chen, L; Chen, Q; Du, M; Gu, W; Li, D; Li, M; Tang, C1
Bonventre, JV; Cravatt, BF; Ewing, H; Gelb, MH; Ghosh, M; Hsu, KL; Lee, H; Leslie, CC; Yun, B1
Colak, S; Kessler, JH; Medema, JP; Mullauer, FB; Potze, L1
Huang, BR; Liao, PJ; Lu, CC; Yen, GC1
Fung, A; Gu, J; Koumpa, FS; Lemaire, A; Lu, K; Ma, D; Ning, J; Sun, JJ; Yi, B; Zhao, H1
Bua, J; Bustos, PL; Milduberger, N; Perrone, AE; Postan, M1
Albert, D; Bergen, A; Burelle, Y; Malo, D; Marton, J; Park, R; Qureshi, S; Vidal, SM; Wiltshire, SA1
Bezu, L; Forveille, S; Kepp, O; Kroemer, G; Liu, P; Müller, K; Pierron, G; Rekdal, Ø; Sauvat, A; Zhou, H; Zitvogel, L1
Gore, E; Groothuis, GM; Olinga, P; Pennings, JL; Vatakuti, S1
Hashimoto, S; Hayashida, S; Honda, M; Inomata, Y; Isono, K; Ohya, Y; Sugawara, Y; Takeichi, T; Yamamoto, H; Yoshii, D1
Bruch, D; Gatto, LA; Kittur, DS; LaSpina, M; Maier, KG; Tripathi, S1
Dorchies, OM; Patthey-Vuadens, O; Reutenauer, J; Ruegg, UT; Vuagniaux, G1
Ateşşahin, A; Ceribaşi, AO; Yüce, A1
Cederbaum, AI; Zhuge, J1
Bernardi, P; Brancolini, C; Crivellato, E; Demarchi, F; Fontanini, A; Foti, C; Maestro, R; Potu, H1
Andoh, TF; Bennett, WM; Shihab, FS1
Krolikowski, JG; Pagel, PS1
Csiko, G; Csizinszky, R; Csordas, A; Domokos, M; Galfi, P; Jakus, J; Neogrady, Z; Szeker, K1
Devalaraja-Narashimha, K; Diener, AM; Padanilam, BJ1
Colantuono, G; Di Venosa, N; Fiore, T; Moro, N; Paradies, G; Petrosillo, G; Ruggiero, FM; Tiravanti, E1
Beaune, P; Bouvier, N; Choukroun, G; Legendre, C; Martinez, F; Pallet, N; Thervet, E1
El-Embaby, A; Grawish, Mel-A; Karrouf, GI; Mahmoud, SH; Sobh, MA; Zaher, AR1
Brentano, TF; Devergie, A; Herr, AL; Orcel, P; Peffault de Latour, R; Petropoulou, AD; Pinto, FO; Porcher, R; Ribaud, P; Robin, M; Rocha, V; Socié, G1
Chen, Y; Dorn, GW; Fujimoto, K; Polonsky, KS1
Abdallah, Y; Erdogan, A; Gündüz, D; Iraqi, W; Kasseckert, SA; Ladilov, Y; Neuhof, C; Piper, HM; Reusch, HP; Said, M; Schlüter, KD; Shahzad, T; Tillmanns, H1
Bernacki, J; Bielecka, A; Gabryel, B; Herman, ZS; Łabuzek, K1
Gieseg, SP; Whiteman, M; Yang, YT1
Bright-Thomas, RJ; Gilchrist, FJ; Jones, AM; Webb, AK1
Cai, H; Eghbali, M; Iorga, A; Li, J; Partow-Navid, R; Rahman, S; Sharma, S; Umar, S; Youn, JY1
Huang, M; Huang, Z; Jin, J; Li, J; Ouyang, Z; Qiu, Y; Zhu, S1
Berra, A; Racca, L; Tau, J; Zapata, G1
Costa, RA; de Souza-Pinto, NC; Fernandes, MP; Vercesi, AE1
Hassoun, Z; Petrovic, LM; Shah, V1
Colao, A; De Rosa, G; Del Puente, A; Esposito, A; Lombardi, G; Risitano, AM; Rotoli, B; Selleri, C; Serio, B; Tauchmanovà, L1
Baelde, HJ; Bruijn, JA; De Heer, E; Lagaaij, EL; Paul, LC; Xu, W1
Chan, JS; Désormeaux, A; Filep, JG; Hébert, MJ; Mollica, L; Raymond, MA; Vigneault, N1
Kim, JS; Lemasters, JJ; Qian, T1
Foreman-Wykert, AK; Miller, JF; Stockbauer, KE1
Brenner, DA; Lemasters, JJ; Oh, KW; Qian, T1
Daller, JA; Hu, M; Hunter, GC; Meng, T; Sower, LE; Woodside, KJ1
Brenner, DA; Kweon, YO; Lemasters, JJ; Paik, YH; Qian, T; Schnabl, B1
Jiang, GP; Li, MW; Xie, HY; Yang, FC; Zeng, QL; Zheng, SS1
Chen, HL; Fowler, C; Gibson, GE; Huang, HM; Ou, HC; Xu, H1
Auber, F; Baudet-Bonneville, V; Bensman, A; Garcette, K; Guigonis, V; Ulinski, T1
Alcover, A; Auger, R; Cadet-Daniel, V; Jungas, T; Kanellopoulos, JM; Mascarell, L; Ojcius, DM; Truffa-Bachi, P1
Hashimoto, T; Hoshi, K; Ikeda, S; Ishii, W; Kato, T; Matsuda, M; Shimojima, Y; Tanaka, Y1
Argaud, L; Chalabreysse, L; Gateau-Roesch, O; Gomez, L; Loufouat, J; Ovize, M; Robert, D; Thivolet-Béjui, F1
Bindoli, A; Bragadin, M; Canton, M; Rigobello, MP; Toninello, A1
Aoki, MS; Miyabara, EH; Moriscot, AS; Salvini, TF; Selistre de Araújo, HS; Tostes, RC1
Ishida, H1
Fortin, MC; Fugère, JA; Hébert, MJ; Madore, F; Pâquet, M; Raymond, MA; St-Louis, G1
Azizian, M; Bruch, D; Kittur, DS; Ramenaden, ER; Shah, G; Wilasrusmee, C1
Capano, M; Crompton, M; Edwards, M; Johnson, N; Li, Y1
Elimadi, A; Haddad, PS; Morin, D; Plin, C; Tillement, JP1
Jaeschke, H; Kim, JS; Kon, K; Lemasters, JJ1
Bodian, CA; Griepp, RB; Haldenwang, PL; Spielvogel, D; Strauch, JT; Tatton, NA; Weisz, D; Zhang, N1
Argaud, L; Gateau-Roesch, O; Loufouat, J; Ovize, M; Raisky, O; Robert, D1
Liot, G; Lobner, D1
Abbott, KC; Agodoa, LY; Bohen, EM; Koff, J; Lentine, KL; Oglesby, RJ; Schnitzler, MA1
Duan, L; Gan, H; He, X; Kornfeld, H; Mirabile-Levens, E; Remold, HG1
Cebecauer, M; Everett, H; Guillaume, P; Hozák, P; Luescher, IF; Mark, S; Schneider, P1
Adachi, S; Akiba, S; Hamahata, K; Imai, T; Katanosaka, Y; Kubota, M; Matsubara, H; Nakahata, T; Okada, M; Toyokuni, SY; Ueno, M; Wakabayashi, S; Watanabe, K1
Brazzola, P; Champagne, J; Champagne, MA; Dalle, JH; Duval, M; Fournet, JC; Gauvin, F1
Bunge, MB; Hill, CE; Moon, LD; Wood, PM1
Bay, A; Eşrefoğlu, M; Kuruş, M; Oztürk, F1
Kamiya, Y; Kaneko, Y; Ohta, K1
Chen, SP; Her, GM; Hong, JR; Jeng, MF; Lin, HY; Wu, JL; Yang, HL1
Aktas, S; Atasoyu, EM; Bilgi, O; Cermik, H; Cimsit, M; Evrenkaya, TR; Gultepe, M; Qyrdedi, T; Uzun, G; Yildiz, S1
Isobe, S; Kobori, M; Nakahara, K; Roy, MK; Takenaka, M; Tsushida, T1
Avilés Izquierdo, J; Chavarria Mur, E; García Sánchez, I; Gilsanz Fernández, C; Molina Sánchez-Cabezudo, F; Vera López, E1
Guo, YL; Li, XH; Lu, S; Ma, X; Wang, ZH; Zhang, X1
Bellyei, S; Bognar, Z; Boronkai, A; Gallyas, F; Gasz, B; Hocsak, E; Minik, O; Sumegi, B; Szigeti, A; Varbiro, G1
Manna, SK; Raghavendra, PB; Ramesh, GT; Sreenivasan, Y1
Dolezel, P; Frydrych, I; Mlejnek, P1
Currin, RT; Lemasters, JJ; Theruvath, TP; Waldmeier, PC; Zhong, Z1
Choi, YK; Jeong, ES; Kim, HC; Lee, CH; Nam, KH; Park, HJ; Park, JI; Won, YS1
Fukamizu, T; Morimoto, S; Sasaki, K; Shoyama, Y; Tanaka, H; Tanaka, Y; Taura, F1
Aoyama, T; Arai, K; Ikejima, K; Kon, K; Lemasters, JJ; Okumura, K; Sato, N; Takei, Y1
Abberger, T; Aydin, S; Jennings, P; Koppelstaetter, C; Mayer, G; Pfaller, W; Wolf, AM1
Arp, J; Faas, SJ; Garcia, B; Gies, DR; Jiang, J; Liu, W; Ramcharran, S; Rother, RP; Wang, H; Zhong, R1
Abellán, A; Garcia-Dorado, D; Miró-Casas, E; Ruiz-Meana, M1
Currin, RT; Holmuhamedov, E; Lemasters, JJ; Pediaditakis, P; Ramshesh, VK; Theruvath, TP; Tikunov, A; Zhong, Z1
Choi, G; Hong, W; Kim, YC; Shin, J; Song, H1
Golstein, P; Kosta, A; Lam, D; Luciani, MF1
Carlen, PL; Feeney, CJ; Frantseva, MV; Mills, LR; Pennefather, PS; Shniffer, C; Shulyakova, N1
Han, J; Kinsey, GR; Schnellmann, RG; Yan, Y; Zhuang, S1
Baines, CP; Barton, ER; Millay, DP; Molkentin, JD; Osinska, H; Robbins, J; Sargent, MA; Sweeney, HL; Vuagniaux, G1
Ito, T; Kimura, T; Kinjo, M; Nakano, I; Nawata, H; Sumii, T; Yamaguchi, H1
Doi, R; Echigo, Y; Higashide, S; Imamura, M; Inoue, K; Kaji, H; Kogire, M; Sumi, S1
Cornu, C; Geubel, A; Goffin, E; Horsmans, Y; Pirson, Y; van Ypersele De Strihou, C1
Fujita, R; Inoue, K; Sekiyama, K; Yoshiba, M1
de Waard-Siebinga, I; de Wolff-Rouendaal, D; Jager, M; van Delft, JL1
Colon, S; Najem, R; Peyrin, JO; Pouteil-Noble, C; Touraine, JL; Yatim, A1
Fujinami, T; Kodera, K; Morozumi, K; Oda, A; Oikawa, T; Sugito, K; Takeda, A; Tominaga, Y; Uchida, K; Yoshida, A1
Anthony, JP; Benhaim, P; Lin, LY; Mathes, SJ; McCalmont, TH1
Bellotti, G; Bocchi, EA; de Lourdes Higuchi, M; Fiorelli, A; Jatene, A; Kalil, J; Pilleggi, F; Stolf, N; Uip, D1
Belitsky, P; Gulanikar, A; Gupta, R; He, G1
Burdick, JF; Keown, P; Marcussen, N; Olsen, S; Racusen, LC; Slatnik, I; Solez, K1
Büttemeyer, R; Jones, NF; Min, Z; Rao, U1
Bertoglio, J; Bohuon, C; Bréard, J; Comisso, M; Pallardy, M; Roger, R1
Bailey, LL; Bouchart, F; Fukushima, N; Gundry, SR; Matsumiya, G; Zuppan, C1
Jordan, SC; Linsley, P; Marchevsky, A; Matloff, J; Matsumara, Y; Zuo, XJ1
Funaoka, M; Hoshino, T; Ishii, T; Kato, J; Kato, K; Komatsu, M; Kuramitsu, T; Masamune, O; Ono, T; Toyoshima, I1
Ankarcrona, M; Dypbukt, JM; Nicotera, P; Orrenius, S1
Arora, AS; Bronk, SF; Gores, GJ; Jones, BJ; Patel, TC1
Folbergrová, J; Li, PA; Siesjö, BK; Smith, ML; Uchino, H1
Harjula, AL; Ikonen, T; Morris, RE; Salminen, US; Taskinen, E; Uusitalo, M1
Chow, CW; Kleinert, S; Weintraub, RG; Wilkinson, JL1
Buhr, HJ; Foitzik, T; Forgacs, B; Gebhardt, MM; Hotz, H; Klar, E; Ryschich, E1
Arras, M; Doll, R; Eckert, P; Mohri, M; Schaper, J; Schaper, W; Strasser, R1
Ang, SG; Jordan, SC; Lai, YH; Marchevsky, A; Matloff, JM; Okada, Y; Ramgolam, VS; Toyoda, M; Yap, HK; Zuo, XJ1
Doi, K; Ishikawa, M; Nakanishi, K; Nakauchi, M; Sakurai, A; Taniguchi, Y1
Bradham, CA; Brenner, DA; Cascio, WE; Crowe, RA; Elmore, SP; Herman, B; Lemasters, JJ; Nieminen, AL; Nishimura, Y; Qian, T; Trost, LC1
Alho, H; Harjula, AL; Ikonen, T; Maasilta, P; Salminen, US; Taskinen, E1
Dempsey, M; Healy, E; Lally, C; Ryan, MP1
Herman, B; Lemasters, JJ; Qian, T1
Choi, DW; Costa, E; Gwag, BJ; Hartley, DM; Jou, I; Ryu, BR1
Brambilla, L; Cantoni, O; Sestili, P1
Cahill, A; Hoek, JB; Marcineviciute, A; Pastorino, JG1
Scheff, SW; Sullivan, PG; Thompson, MB1
Friedmann, JM; Hauser, IA; Katsen, AD; Thévenod, F1
Bargalló, N; Berenguer, J; Buñesch, L; Burrel, M; Cofan, F; Mercader, JM1
Kong, JY; Rabkin, SW1
Frame, JD; MacKenzie, D; Moiemen, N1
Alimonti, J; Brown, T; Cizeau, J; Dubik, D; Greenberg, AH; Hakem, R; Israels, S; Vande Velde, C1
Brown, RA; Kuo, TH; Ling, S; Yu, XD; Zhu, LP1
Bal-Price, A; Brown, GC1
Elonen, E; Juvonen, E; Parkkali, T; Ruutu, T; Volin, L1
Dragun, D; Haller, H; Hoff, U; Luft, FC; Park, JK; Qun, Y; Schneider, W1
Almeida, A; Bolaños, JP1
Cederbaum, AI; Wu, D1
Cantoni, O; Sestili, P; Tommasini, I1
Brandacher, G; Margreiter, R; Obrist, P; Steurer, W; Werner, ER; Werner-Felmayer, G; Zou, Y1
Breitbart, A; Fiehn, C; Germann, G1
Jiang, D; Sensi, SL; Steward, O; Sullivan, PG; Weiss, JH1
Günter-Duwe, D; Mazzucchelli, L; Redaelli, CA; Schilling, MK; Schmid, RA; Stahel, PF; Tian, YH; Wagner, M1
Acevedo, A; Escudero, A; Fernández-Rañada, JM; Gil-Fernández, JJ; Martínez, E; Martínez-Chamorro, C1
Gil, DP; Patiño, P; Rojas, M; Rugeles, MT1
Almirall, J; Andreu, J; Bru, C; Campistol, JM; Oppenheimer, F; Revert, L; Sole, M1
Almirall, J; Andreu, J; Bru, C; Campistol, JM; Muntane, J; Oppenheimer, F; Revert, L; Sole, M1
Caccamo, L; Colledan, M; Gatti, S; Gridelli, B; Lucianetti, A; Maggi, U; Paone, G; Piazzini Albani, A; Reggiani, P; Rossi, G1
Eydelloth, RS; Germershausen, JI; Grossman, SJ; MacDonald, JS; Schwartz, MS; Smith, PF; Stubbs, RJ1
Burtomboy, G; Cames, B; de Ville de Goyet, J; Lamy, M; Otte, JB; Rahier, J; Reding, R; Sokal, EM1
Canales-Treviño, ML; Martínez-Palomo, A; Tsutsumi, V1

Reviews

3 review(s) available for cyclosporine and Necrosis

ArticleYear
[The research method for investigating the role of the mitochondrial permeability transition pore in cell death].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2004, Volume: 123, Issue:5

    Topics: Apoptosis; Arsenicals; Calcium; Cyclosporine; Cytochromes c; Diazoxide; Humans; Ion Channels; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Reperfusion Injury; Myocardium; Necrosis; Ouabain

2004
The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy.
    Biochimica et biophysica acta, 1998, Aug-10, Volume: 1366, Issue:1-2

    Topics: Animals; Apoptosis; Autophagy; Calcimycin; Calcium; Cells, Cultured; Cyclosporine; Fluoresceins; Hydrogen-Ion Concentration; Microscopy, Confocal; Mitochondria; Mitochondria, Liver; Necrosis; Oxidative Stress; Permeability; Peroxides; Reactive Oxygen Species; Rhodamines; Superoxides; tert-Butylhydroperoxide

1998
Acute necrotizing gastritis by Escherichia coli in a severely neutropenic patient.
    Haematologica, 2002, Volume: 87, Issue:1

    Topics: Acute Disease; Amikacin; Anemia, Aplastic; Antilymphocyte Serum; Combined Modality Therapy; Cyclosporine; Drug Therapy, Combination; Escherichia coli Infections; Gastric Mucosa; Gastritis; Granulocyte Colony-Stimulating Factor; Immunosuppressive Agents; Meropenem; Methylprednisolone; Necrosis; Neutropenia; Omeprazole; Parenteral Nutrition, Total; T-Lymphocytes; Thienamycins

2002

Trials

3 trial(s) available for cyclosporine and Necrosis

ArticleYear
Interferon and cyclosporin A in the treatment of fulminant viral hepatitis.
    Journal of gastroenterology, 1995, Volume: 30, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Aged; Combined Modality Therapy; Cyclosporine; Female; Hepatic Encephalopathy; Hepatitis B; Hepatitis C; Hepatitis E; Hepatitis, Viral, Human; Humans; Infant; Interferon-beta; Liver; Male; Middle Aged; Necrosis

1995
Cyclosporine, methotrexate, and methylprednisolone compared with cyclosporine and methotrexate for the prevention of graft-versus-host disease in bone marrow transplantation from HLA-identical sibling donor: a prospective randomized study.
    Blood, 2000, Oct-01, Volume: 96, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Blood Transfusion; Bone and Bones; Bone Marrow Transplantation; Cause of Death; Chronic Disease; Cyclosporine; Female; Graft vs Host Disease; Hematologic Neoplasms; Histocompatibility Testing; Hospitalization; Humans; Infections; Male; Methotrexate; Methylprednisolone; Middle Aged; Necrosis; Nuclear Family; Prospective Studies; Recurrence; Survival Rate

2000
Clinical usefulness of conventional fine needle aspiration cytology in kidney transplantation--influence of different immunosuppressive protocols.
    Transplantation proceedings, 1992, Volume: 24, Issue:1

    Topics: Antilymphocyte Serum; Azathioprine; Cyclosporine; Humans; Immunosuppression Therapy; Kidney Transplantation; Kidney Tubules; Necrosis; Prednisone; Prospective Studies

1992

Other Studies

149 other study(ies) available for cyclosporine and Necrosis

ArticleYear
Modulation of P-glycoprotein-mediated multidrug resistance by flavonoid derivatives and analogues.
    Journal of medicinal chemistry, 2003, May-22, Volume: 46, Issue:11

    Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Division; Chromones; Daunorubicin; Drug Resistance, Multiple; Drug Synergism; Flavonoids; Fluorescent Dyes; Humans; Necrosis; Piperazines; Quinolinium Compounds; Rhodamine 123; Thiazoles; Tumor Cells, Cultured

2003
Small Molecule Inhibitors of Cyclophilin D To Protect Mitochondrial Function as a Potential Treatment for Acute Pancreatitis.
    Journal of medicinal chemistry, 2016, Mar-24, Volume: 59, Issue:6

    Topics: Amino Acid Sequence; Animals; Cell Line; Crystallography, X-Ray; Cyclophilins; Drug Design; Humans; Membrane Potential, Mitochondrial; Mice; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Models, Molecular; Molecular Docking Simulation; Molecular Sequence Data; Necrosis; Pancreatitis, Acute Necrotizing; Peptidyl-Prolyl Isomerase F; Pyrrolidines; Signal Transduction; Small Molecule Libraries; Thermodynamics; Urea

2016
Evanescing renal allograft cortical necrosis from living donor renal transplantation: A lesson learned over two decades.
    Transplant immunology, 2022, Volume: 71

    Topics: Allografts; Cyclosporine; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Kidney Transplantation; Living Donors; Necrosis; Retrospective Studies; Tacrolimus

2022
Postconditioning by Delayed Administration of Ciclosporin A: Implication for Donation after Circulatory Death (DCD).
    International journal of molecular sciences, 2022, Oct-25, Volume: 23, Issue:21

    Topics: Animals; Cyclosporine; Heart Arrest; Mitochondrial Permeability Transition Pore; Myocardial Reperfusion Injury; Necrosis; Rats

2022
Cyclosporine A attenuates apoptosis and necrosis after ischemia-reperfusion-induced renal injury in transiently hyperglycemic rats.
    Acta cirurgica brasileira, 2017, Volume: 32, Issue:3

    Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Apoptosis; Cell Survival; Cyclosporine; Flow Cytometry; Hyperglycemia; Ischemia; Isoflurane; Kidney; Male; Necrosis; Premedication; Propofol; Protective Agents; Random Allocation; Rats, Wistar; Reperfusion Injury; Reproducibility of Results; Time Factors; Treatment Outcome

2017
Mitochondrial permeability transition involves dissociation of F
    EMBO reports, 2017, Volume: 18, Issue:7

    Topics: Adenosine Triphosphate; Animals; Biological Transport; Cyclosporine; HEK293 Cells; Humans; Mice; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Membranes; Mitochondrial Proton-Translocating ATPases; Necrosis; Permeability; Protein Conformation; Protein Multimerization; Rats

2017
Does necroptosis have a crucial role in hepatic ischemia-reperfusion injury?
    PloS one, 2017, Volume: 12, Issue:9

    Topics: Animals; Apoptosis; Caspase 3; Cyclosporine; Disease Models, Animal; GTPase-Activating Proteins; Liver; Male; Mice, Inbred C57BL; Necrosis; Receptor-Interacting Protein Serine-Threonine Kinases; Reperfusion Injury

2017
Critical contribution of RIPK1 mediated mitochondrial dysfunction and oxidative stress to compression-induced rat nucleus pulposus cells necroptosis and apoptosis.
    Apoptosis : an international journal on programmed cell death, 2018, Volume: 23, Issue:5-6

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Cells, Cultured; Cyclosporine; Imidazoles; Indoles; Intervertebral Disc Degeneration; Malondialdehyde; Mitochondria; Mitochondrial Membranes; Necrosis; Nucleus Pulposus; Oxidative Stress; Protein Serine-Threonine Kinases; Rats; Reactive Oxygen Species; Receptor-Interacting Protein Serine-Threonine Kinases; Superoxide Dismutase; Weight-Bearing

2018
CYCLOSPORIN H: A NOVEL ANTI-INFLAMMATORY THERAPY FOR INFLUENZA FLU PATIENTS.
    Journal of the Egyptian Society of Parasitology, 2017, Volume: 47, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Chemotaxis, Leukocyte; Cyclosporine; Dogs; Female; Humans; Inflammation; Influenza A Virus, H1N1 Subtype; Influenza, Human; Leukocytes; Madin Darby Canine Kidney Cells; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred BALB C; Necrosis; Staphylococcal Infections

2017
Treatment With Cyclosporine A for Statin-Naïve Anti-HMGCR Antibody-Associated Necrotizing Myopathy.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2019, Volume: 25, Issue:5

    Topics: Adult; Antirheumatic Agents; Autoantibodies; Biopsy; Cyclosporine; Female; Humans; Hydroxymethylglutaryl CoA Reductases; Middle Aged; Muscle, Skeletal; Muscular Diseases; Necrosis; Treatment Outcome

2019
Enhanced cell-volume regulation in cyclosporin A cardioprotection.
    Cardiovascular research, 2013, Jun-01, Volume: 98, Issue:3

    Topics: Animals; Cell Size; Cells, Cultured; Chloride Channels; Chlorides; Cyclosporine; Cytoprotection; Ion Transport; Membrane Potential, Mitochondrial; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Reperfusion Injury; Myocytes, Cardiac; Necrosis; Osmotic Pressure; Protective Agents; Rabbits; Time Factors

2013
Cyclosporin A enhances the ability of trophoblasts to displace the activated human umbilical vein endothelial cell monolayers.
    International journal of clinical and experimental pathology, 2013, Volume: 6, Issue:11

    Topics: Antigens, CD; Cadherins; Cell Adhesion; Cell Line, Tumor; Cell Movement; Chemokine CXCL12; Coculture Techniques; Connectin; Cyclosporine; Female; Human Umbilical Vein Endothelial Cells; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Necrosis; Placentation; Pregnancy; Signal Transduction; Trophoblasts; Tumor Necrosis Factor-alpha

2013
Serine hydrolase inhibitors block necrotic cell death by preventing calcium overload of the mitochondria and permeability transition pore formation.
    The Journal of biological chemistry, 2014, Jan-17, Volume: 289, Issue:3

    Topics: Animals; Arachidonic Acid; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cell Line, Transformed; Chelating Agents; Cyclosporine; Diglycerides; Egtazic Acid; Fibroblasts; Group IV Phospholipases A2; Isoenzymes; L-Lactate Dehydrogenase; Mice; Mice, Knockout; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Necrosis; Phospholipase A2 Inhibitors; Pyrrolidines; Thapsigargin

2014
Betulinic acid-induced mitochondria-dependent cell death is counterbalanced by an autophagic salvage response.
    Cell death & disease, 2014, Apr-10, Volume: 5

    Topics: Animals; Apoptosis; Autophagy; Betulinic Acid; Cell Line, Tumor; Cyclosporine; Humans; Mice; Mitochondria; Necrosis; Pentacyclic Triterpenes; Signal Transduction; Triterpenes

2014
Ursolic acid triggers nonprogrammed death (necrosis) in human glioblastoma multiforme DBTRG-05MG cells through MPT pore opening and ATP decline.
    Molecular nutrition & food research, 2014, Volume: 58, Issue:11

    Topics: Adenosine Triphosphate; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Cell Line, Tumor; Cell Survival; Cyclophilins; Cyclosporine; DNA Damage; Glioblastoma; Humans; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Necrosis; Peptidyl-Prolyl Isomerase F; Reactive Oxygen Species; Signal Transduction; Triterpenes; Ursolic Acid

2014
Necroptosis and parthanatos are involved in remote lung injury after receiving ischemic renal allografts in rats.
    Kidney international, 2015, Volume: 87, Issue:4

    Topics: Acute Lung Injury; Animals; Benzamides; Cells, Cultured; Culture Media, Conditioned; Cyclosporine; DNA Fragmentation; Graft Rejection; Humans; Imidazoles; Immunosuppressive Agents; Indoles; Kidney Transplantation; Kidney Tubules, Proximal; Lung; Male; Necrosis; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Protein Serine-Threonine Kinases; Rats; Rats, Inbred BN; Rats, Inbred Lew; Receptor-Interacting Protein Serine-Threonine Kinases; Reperfusion Injury; Transplantation, Homologous; Tumor Necrosis Factor-alpha

2015
Oxidative stress damage in the protozoan parasite Trypanosoma cruzi is inhibited by Cyclosporin A.
    Parasitology, 2015, Volume: 142, Issue:8

    Topics: Apoptosis; Calcineurin Inhibitors; Cell Death; Cyclophilins; Cyclosporine; Cytochromes c; Fluoresceins; Fluorescent Dyes; Hydrogen Peroxide; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Necrosis; Oxidative Stress; Protozoan Proteins; Reactive Oxygen Species; Trypanosoma cruzi

2015
Cyclosporine A Treatment Inhibits Abcc6-Dependent Cardiac Necrosis and Calcification following Coxsackievirus B3 Infection in Mice.
    PloS one, 2015, Volume: 10, Issue:9

    Topics: Animals; ATP-Binding Cassette Transporters; Calcinosis; Coxsackievirus Infections; Cyclophilins; Cyclosporine; Enterovirus B, Human; Female; Immunosuppressive Agents; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Electron, Transmission; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Multidrug Resistance-Associated Proteins; Myocarditis; Necrosis; Peptidyl-Prolyl Isomerase F

2015
The oncolytic peptide LTX-315 triggers necrotic cell death.
    Cell cycle (Georgetown, Tex.), 2015, Volume: 14, Issue:21

    Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Bone Neoplasms; Caspase Inhibitors; Cell Line, Tumor; Cyclosporine; Dose-Response Relationship, Drug; Humans; Imidazoles; Indoles; Microscopy, Electron, Transmission; Necrosis; Oligopeptides; Osteosarcoma; Time Factors

2015
Classification of Cholestatic and Necrotic Hepatotoxicants Using Transcriptomics on Human Precision-Cut Liver Slices.
    Chemical research in toxicology, 2016, Mar-21, Volume: 29, Issue:3

    Topics: Acetaminophen; Aged; Benzofurans; Bile Acids and Salts; Chloramphenicol; Chlorpromazine; Cholestasis; Colchicine; Cyclosporine; Diethylnitrosamine; Drug-Related Side Effects and Adverse Reactions; Ethinyl Estradiol; Female; Gene Expression Profiling; Hepatocytes; Humans; Liver; Male; Methyltestosterone; Middle Aged; Necrosis; Phenotype; Toxicogenetics; Young Adult

2016
Intravital Imaging of Neutrophil Recruitment Reveals the Efficacy of FPR1 Blockade in Hepatic Ischemia-Reperfusion Injury.
    Journal of immunology (Baltimore, Md. : 1950), 2017, 02-15, Volume: 198, Issue:4

    Topics: Animals; Apoptosis; Chemokines; Chemotaxis, Leukocyte; Cyclosporine; Cytokines; Intravital Microscopy; Liver; Male; Mice; Monocytes; Necrosis; Neutrophil Infiltration; Neutrophils; Receptors, Formyl Peptide; Reperfusion Injury

2017
An interleukin-6-neutralizing antibody prevents cyclosporine-induced nephrotoxicity in mice.
    The Journal of surgical research, 2008, Volume: 148, Issue:2

    Topics: Acetophenones; Animals; Antibodies, Monoclonal; Cyclosporine; Diet, Sodium-Restricted; Disease Models, Animal; Immunosuppressive Agents; Interleukin-6; Kidney; Kidney Diseases; Kidney Tubules; Male; Mice; Mice, Inbred C57BL; NADPH Oxidases; Necrosis

2008
Investigation of Debio 025, a cyclophilin inhibitor, in the dystrophic mdx mouse, a model for Duchenne muscular dystrophy.
    British journal of pharmacology, 2008, Volume: 155, Issue:4

    Topics: Animals; Animals, Newborn; Cell Death; Cyclophilins; Cyclosporine; Diaphragm; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Delivery Systems; Female; Hindlimb; Male; Mice; Mice, Inbred mdx; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Muscle, Skeletal; Muscular Dystrophy, Animal; Muscular Dystrophy, Duchenne; Necrosis

2008
Amelioration of cyclosporine A-induced renal, hepatic and cardiac damages by ellagic acid in rats.
    Basic & clinical pharmacology & toxicology, 2008, Volume: 103, Issue:2

    Topics: Animals; Antioxidants; Cyclosporine; Ellagic Acid; Immunosuppressive Agents; Kidney; Lipid Peroxidation; Liver; Male; Myocardium; Necrosis; Oxidative Stress; Rats; Rats, Sprague-Dawley

2008
Inhibition of the mitochondrial permeability transition by cyclosporin A prevents pyrazole plus lipopolysaccharide-induced liver injury in mice.
    Free radical biology & medicine, 2009, Feb-01, Volume: 46, Issue:3

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cyclosporine; Lipid Peroxidation; Lipopolysaccharides; Liver; Liver Diseases; Mice; Mice, Inbred C57BL; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitogen-Activated Protein Kinase 9; Necrosis; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-bcl-2; Pyrazoles; Signal Transduction

2009
The Isopeptidase Inhibitor G5 Triggers a Caspase-independent Necrotic Death in Cells Resistant to Apoptosis: A COMPARATIVE STUDY WITH THE PROTEASOME INHIBITOR BORTEZOMIB.
    The Journal of biological chemistry, 2009, Mar-27, Volume: 284, Issue:13

    Topics: Actins; Animals; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; bcl-X Protein; Boronic Acids; Bortezomib; Carbon-Nitrogen Lyases; Cell Adhesion; Cell Line, Transformed; Collagen; Cyclosporine; Cytoskeleton; Extracellular Matrix; Fibronectins; HMGB1 Protein; MAP Kinase Kinase 4; Membrane Potential, Mitochondrial; Mice; Mice, Knockout; Necrosis; Peroxisome Proliferator-Activated Receptors; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrans; Pyrazines; Sulfhydryl Compounds

2009
Donor preconditioning with a calcineurin inhibitor improves outcome in rat syngeneic kidney transplantation.
    Transplantation, 2009, Feb-15, Volume: 87, Issue:3

    Topics: Animals; Creatinine; Cyclosporine; Immunosuppressive Agents; Inflammation; Kidney Transplantation; Kidney Tubules; Models, Animal; Necrosis; Rats; Rats, Inbred F344; Tacrolimus; Transplantation Conditioning; Transplantation, Homologous; Transplantation, Isogeneic; Treatment Outcome

2009
Transient metabolic alkalosis during early reperfusion abolishes helium preconditioning against myocardial infarction: restoration of cardioprotection by cyclosporin A in rabbits.
    Anesthesia and analgesia, 2009, Volume: 108, Issue:4

    Topics: Acidosis; Administration, Inhalation; Alkalosis; Animals; Cyclosporine; Disease Models, Animal; Drug Administration Schedule; Helium; Hemodynamics; Male; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Necrosis; Rabbits; Sodium Bicarbonate

2009
Butyrate-induced cell death and differentiation are associated with distinct patterns of ROS in HT29-derived human colon cancer cells.
    Digestive diseases and sciences, 2010, Volume: 55, Issue:4

    Topics: Antioxidants; Apoptosis; Butyrates; Cell Adhesion; Cell Death; Cell Differentiation; Cell Division; Cyclosporine; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Free Radicals; HT29 Cells; Humans; Hydrogen Peroxide; Immunosuppressive Agents; In Situ Nick-End Labeling; Isoquinolines; Necrosis; Reactive Oxygen Species; Resveratrol; Stilbenes

2010
Cyclophilin D gene ablation protects mice from ischemic renal injury.
    American journal of physiology. Renal physiology, 2009, Volume: 297, Issue:3

    Topics: Adenosine Triphosphate; Animals; Blood Urea Nitrogen; Creatinine; Cyclophilins; Cyclosporine; Disease Models, Animal; Epithelial Cells; Hydrogen Peroxide; Kidney; L-Lactate Dehydrogenase; LLC-PK1 Cells; Membrane Potential, Mitochondrial; Mice; Mice, Knockout; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Necrosis; Neutrophil Infiltration; Oxidants; Oxidative Stress; Peptidyl-Prolyl Isomerase F; Reperfusion Injury; Swine; Time Factors

2009
Melatonin protects against heart ischemia-reperfusion injury by inhibiting mitochondrial permeability transition pore opening.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 297, Issue:4

    Topics: Animals; Antioxidants; Calcium; Cardiolipins; Cardiovascular Agents; Cyclosporine; Cytochromes c; Heart Rate; In Vitro Techniques; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Melatonin; Membrane Potential, Mitochondrial; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NAD; Necrosis; Perfusion; Rats; Rats, Wistar; Recovery of Function; Time Factors; Ventricular Function, Left; Ventricular Pressure

2009
Antiapoptotic properties of recombinant human erythropoietin protects against tubular cyclosporine toxicity.
    Pharmacological research, 2010, Volume: 61, Issue:1

    Topics: Acute Disease; Animals; Apoptosis; Biomarkers; Blotting, Western; Caspase 3; Creatinine; Cyclosporine; Cytoprotection; Disease Models, Animal; Erythropoietin; Humans; In Situ Nick-End Labeling; Kidney Cortex Necrosis; Kidney Tubules; Male; Necrosis; Phosphorylation; Protective Agents; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Signal Transduction

2010
Influence of selective immunosuppressive drugs on the healing of exposed dogs' dental pulp capped with mineral trioxide aggregate.
    Journal of endodontics, 2010, Volume: 36, Issue:1

    Topics: Aluminum Compounds; Animals; Calcium Compounds; Cyclosporine; Dental Pulp; Dental Pulp Capping; Dental Pulp Exposure; Dentin, Secondary; Dogs; Drug Combinations; Immunosuppressive Agents; Male; Mycophenolic Acid; Necrosis; Oxides; Prednisone; Pulpitis; Silicates; Sirolimus; Wound Healing

2010
Prospective assessment of bone turnover and clinical bone diseases after allogeneic hematopoietic stem-cell transplantation.
    Transplantation, 2010, Jun-15, Volume: 89, Issue:11

    Topics: Adolescent; Adult; Bone and Bones; Bone Density; Bone Diseases; Child; Collagen Type I; Cyclosporine; Female; Fractures, Bone; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Incidence; Male; Necrosis; Peptides; Risk Factors; Sex Characteristics; Time Factors; Transplantation, Homologous; Whole-Body Irradiation

2010
Targeting cyclophilin D and the mitochondrial permeability transition enhances beta-cell survival and prevents diabetes in Pdx1 deficiency.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Jun-01, Volume: 107, Issue:22

    Topics: Animals; Animals, Newborn; Apoptosis; Cell Line; Cell Survival; Cyclophilins; Cyclosporine; Diabetes Mellitus, Type 1; Homeodomain Proteins; Humans; Insulin-Secreting Cells; Membrane Potential, Mitochondrial; Mice; Mice, Knockout; Microscopy, Electron, Transmission; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Necrosis; Peptidyl-Prolyl Isomerase F; Trans-Activators

2010
Interplay between Ca2+ cycling and mitochondrial permeability transition pores promotes reperfusion-induced injury of cardiac myocytes.
    Journal of cellular and molecular medicine, 2011, Volume: 15, Issue:11

    Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Calcium; Cyclosporine; Fluoresceins; Male; Membrane Potential, Mitochondrial; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Reperfusion Injury; Myocytes, Cardiac; Necrosis; Rats; Rats, Wistar; Reactive Oxygen Species; Ruthenium Compounds; Ryanodine; Thapsigargin; Tiopronin

2011
Immunosuppressant cytoprotection correlates with HMGB1 suppression in primary astrocyte cultures exposed to combined oxygen-glucose deprivation.
    Pharmacological reports : PR, 2011, Volume: 63, Issue:2

    Topics: Animals; Astrocytes; Cell Hypoxia; Cells, Cultured; Cyclosporine; Dose-Response Relationship, Drug; Glucose; HMGB1 Protein; Immunosuppressive Agents; Inflammation; Inflammation Mediators; Ischemia; Necrosis; Oxidative Stress; Rats; Rats, Wistar; Sirolimus; Tacrolimus

2011
HOCl causes necrotic cell death in human monocyte derived macrophages through calcium dependent calpain activation.
    Biochimica et biophysica acta, 2012, Volume: 1823, Issue:2

    Topics: Calcimycin; Calcium; Calcium Channel Blockers; Calcium Ionophores; Calpain; Caspase 3; Cyclosporine; Dantrolene; Enzyme Inhibitors; Flunarizine; Humans; Hypochlorous Acid; Lysosomes; Macrophages; Membrane Potential, Mitochondrial; Muscle Relaxants, Central; Necrosis; Nifedipine; Verapamil

2012
Successful treatment of cepacia syndrome with a combination of intravenous cyclosporin, antibiotics and oral corticosteroids.
    Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2012, Volume: 11, Issue:5

    Topics: Administration, Intravenous; Adrenal Cortex Hormones; Adult; Anti-Bacterial Agents; Burkholderia cepacia complex; Burkholderia Infections; Cyclosporine; Cystic Fibrosis; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Lung; Male; Necrosis; Pneumonia, Bacterial; Sputum; Syndrome; Treatment Outcome

2012
Intralipid, a clinically safe compound, protects the heart against ischemia-reperfusion injury more efficiently than cyclosporine-A.
    Anesthesiology, 2012, Volume: 117, Issue:4

    Topics: Animals; Anterior Wall Myocardial Infarction; Blotting, Western; Calcium; Cardiotonic Agents; Coronary Vessels; Cyclosporine; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Emulsions; Fat Emulsions, Intravenous; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Heart Function Tests; Immunosuppressive Agents; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mitochondria, Heart; Myocardial Reperfusion Injury; Necrosis; Oncogene Protein v-akt; Permeability; Phospholipids; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Soybean Oil

2012
Necroptosis contributes to the cyclosporin A-induced cytotoxicity in NRK-52E cells.
    Die Pharmazie, 2012, Volume: 67, Issue:8

    Topics: Animals; Apoptosis; Benzimidazoles; Blotting, Western; Cell Death; Cell Line; Cyclosporine; Flow Cytometry; Imidazoles; Immunosuppressive Agents; Indoles; Kidney Tubular Necrosis, Acute; L-Lactate Dehydrogenase; Necrosis; Rats; Reactive Oxygen Species; RNA, Small Interfering

2012
Topical use of rapamycin in herpetic stromal keratitis.
    Ocular immunology and inflammation, 2012, Volume: 20, Issue:5

    Topics: Administration, Ophthalmic; Animals; Antiviral Agents; Corneal Stroma; Cyclosporine; Dexamethasone; Herpesvirus 1, Human; Keratitis, Herpetic; Mice; Mice, Inbred BALB C; Necrosis; Neovascularization, Pathologic; Severity of Illness Index; Sirolimus; Treatment Outcome

2012
Protective effects of l-carnitine and piracetam against mitochondrial permeability transition and PC3 cell necrosis induced by simvastatin.
    European journal of pharmacology, 2013, Feb-15, Volume: 701, Issue:1-3

    Topics: Carnitine; Cell Line, Tumor; Cyclosporine; Drug Synergism; Humans; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Necrosis; Piracetam; Simvastatin; Superoxides

2013
The choice of calcineurin inhibitor does not influence centrilobular necrosis after orthotopic liver transplantation.
    Transplantation proceedings, 2002, Volume: 34, Issue:5

    Topics: Biopsy; Calcineurin Inhibitors; Cyclosporine; Humans; Immunosuppressive Agents; Liver Transplantation; Necrosis; Postoperative Complications; Retrospective Studies; Tacrolimus

2002
Long-lasting bone damage detected by dual-energy x-ray absorptiometry, phalangeal osteosonogrammetry, and in vitro growth of marrow stromal cells after allogeneic stem cell transplantation.
    The Journal of clinical endocrinology and metabolism, 2002, Volume: 87, Issue:11

    Topics: Absorptiometry, Photon; Adult; Aged; Bone Density; Bone Diseases; Bone Marrow Cells; Cells, Cultured; Colony-Forming Units Assay; Cross-Sectional Studies; Cyclosporine; Female; Graft vs Host Disease; Humans; Immunosuppressive Agents; Male; Necrosis; Stem Cell Transplantation; Stromal Cells; Transplantation, Homologous; Ultrasonography

2002
Endothelial cell chimerism after renal transplantation in a rat model.
    Transplantation, 2002, Nov-15, Volume: 74, Issue:9

    Topics: Animals; Cyclosporine; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Graft Rejection; Immunosuppression Therapy; Ischemia; Kidney; Kidney Transplantation; Male; Necrosis; Rats; Rats, Inbred BN; Rats, Inbred Lew; Renal Circulation; Transplantation Chimera

2002
Blockade of the apoptotic machinery by cyclosporin A redirects cell death toward necrosis in arterial endothelial cells: regulation by reactive oxygen species and cathepsin D.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2003, Volume: 17, Issue:3

    Topics: Apoptosis; Arteries; Caspases; Cathepsin D; Cells, Cultured; Cyclosporine; DNA Damage; Endothelium, Vascular; Humans; Lysosomes; Models, Biological; Necrosis; Oxidative Stress; Reactive Oxygen Species

2003
Mitochondrial permeability transition in the switch from necrotic to apoptotic cell death in ischemic rat hepatocytes.
    Gastroenterology, 2003, Volume: 124, Issue:2

    Topics: Animals; Apoptosis; Caspase 3; Caspase Inhibitors; Caspases; Cells, Cultured; Cyclosporine; Energy Metabolism; Enzyme Inhibitors; Fructose; Glycine; Glycolysis; Hepatocytes; In Situ Nick-End Labeling; Ischemia; Liver Circulation; Male; Mitochondria, Liver; Necrosis; Permeability; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Staining and Labeling

2003
Bordetella type III secretion induces caspase 1-independent necrosis.
    Cellular microbiology, 2003, Volume: 5, Issue:2

    Topics: Animals; Bacterial Toxins; Bordetella bronchiseptica; Caspase 1; Cell Death; Cell Line; Cyclosporine; Glycine; HeLa Cells; Humans; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Necrosis

2003
Salicylate enhances necrosis and apoptosis mediated by the mitochondrial permeability transition.
    Toxicological sciences : an official journal of the Society of Toxicology, 2003, Volume: 73, Issue:1

    Topics: Animals; Apoptosis; Calcimycin; Calcium; Caspase 3; Caspases; Cell Line, Tumor; Cell Survival; Cyclosporine; Hepatocytes; Humans; Immunosuppressive Agents; In Vitro Techniques; Ionophores; Male; Microscopy, Confocal; Mitochondria; Necrosis; Oxidative Stress; Permeability; Rats; Rats, Sprague-Dawley; Salicylates; tert-Butylhydroperoxide; Tumor Necrosis Factor-alpha

2003
Differential effects of interleukin-2 blockade on apoptosis in naïve and activated human lymphocytes.
    Transplantation, 2003, May-27, Volume: 75, Issue:10

    Topics: Animals; Antibodies, Monoclonal; Antilymphocyte Serum; Apoptosis; Basiliximab; Calcineurin Inhibitors; Cells, Cultured; Cyclosporine; fas Receptor; Humans; Immunosuppressive Agents; Interleukin-2; Lymphocyte Activation; Lymphocytes; Necrosis; Proto-Oncogene Proteins c-bcl-2; Rabbits; Recombinant Fusion Proteins

2003
Gliotoxin-mediated apoptosis of activated human hepatic stellate cells.
    Journal of hepatology, 2003, Volume: 39, Issue:1

    Topics: Adenosine Triphosphate; Annexin A5; Apoptosis; Caspase 3; Caspases; Cell Line, Transformed; Cyclosporine; Cytochromes c; Cytosol; Dopamine Antagonists; Gliotoxin; Humans; Immunosuppressive Agents; Liver; Liver Cirrhosis; Mitochondria; Necrosis; NF-kappa B; Oxidative Stress; Protein Binding; Reactive Oxygen Species; Trifluoperazine

2003
[Influence of combined cyclosporine A and tacrolimus with 5-fluorouracil on hepatocellular carcinoma rats].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 2003, Volume: 41, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Hepatocellular; Cyclosporine; Fluorouracil; Liver Neoplasms; Male; Membrane Potentials; Mitochondria; Necrosis; Rats; Rats, Wistar; Tacrolimus

2003
Inhibition of alpha-ketoglutarate dehydrogenase complex promotes cytochrome c release from mitochondria, caspase-3 activation, and necrotic cell death.
    Journal of neuroscience research, 2003, Oct-15, Volume: 74, Issue:2

    Topics: Animals; Caspase 3; Caspases; Cell Death; Cell Membrane Permeability; Chromatin; Cyclosporine; Cytochromes c; Ion Channels; Keto Acids; Ketoglutarate Dehydrogenase Complex; L-Lactate Dehydrogenase; Matrix Metalloproteinases; Membrane Potentials; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Necrosis; Neurodegenerative Diseases; Neurons; PC12 Cells; Protein Transport; Rats; Reactive Oxygen Species

2003
Mesenteric thrombosis causing short bowel syndrome in nephrotic syndrome.
    Pediatric nephrology (Berlin, Germany), 2003, Volume: 18, Issue:12

    Topics: Child, Preschool; Cyclophosphamide; Cyclosporine; Humans; Immunosuppressive Agents; Infarction; Male; Necrosis; Nephrotic Syndrome; Short Bowel Syndrome; Splanchnic Circulation; Steroids; Tetrahydrofolate Dehydrogenase; Thrombosis

2003
Characterization of a gene encoding two isoforms of a mitochondrial protein up-regulated by cyclosporin A in activated T cells.
    The Journal of biological chemistry, 2004, Mar-12, Volume: 279, Issue:11

    Topics: Alternative Splicing; Amino Acid Sequence; Animals; Apoptosis; Base Sequence; Blotting, Western; Calcineurin; Cell Line; Cell Membrane; Cyclosporine; Cytochromes c; DNA, Complementary; Endopeptidase K; Flow Cytometry; Genome; Green Fluorescent Proteins; Humans; Immunosuppressive Agents; In Vitro Techniques; Intracellular Membranes; Luminescent Proteins; Lymphocyte Activation; Membrane Proteins; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Mitochondria; Mitochondrial Proteins; Molecular Sequence Data; Necrosis; Peptides; Plasmids; Protein Isoforms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Subcellular Fractions; T-Lymphocytes; Time Factors; Tissue Distribution; Transfection; Up-Regulation

2004
Intractable skin necrosis and interstitial pneumonia in amyopathic dermatomyositis, successfully treated with cyclosporin A.
    Internal medicine (Tokyo, Japan), 2003, Volume: 42, Issue:12

    Topics: Adult; Cyclosporine; Dermatomyositis; Humans; Immunoglobulins, Intravenous; Immunosuppressive Agents; Lung Diseases, Interstitial; Male; Necrosis; Skin

2003
Preconditioning delays Ca2+-induced mitochondrial permeability transition.
    Cardiovascular research, 2004, Jan-01, Volume: 61, Issue:1

    Topics: Animals; Apoptosis; Calcium; Cyclosporine; Immunosuppressive Agents; In Situ Nick-End Labeling; Intracellular Membranes; Ischemic Preconditioning, Myocardial; Male; Microscopy, Electron; Mitochondria, Heart; Myocardial Infarction; Myocytes, Cardiac; Necrosis; Permeability; Rabbits; Random Allocation

2004
Thallium induces apoptosis in Jurkat cells.
    Annals of the New York Academy of Sciences, 2003, Volume: 1010

    Topics: Apoptosis; Cell Survival; Cyclosporine; Humans; Intracellular Membranes; Jurkat Cells; Mitochondria; Mitochondrial Swelling; Necrosis; Phosphates; Thallium

2003
Cyclosporin A attenuates skeletal muscle damage induced by crotoxin in rats.
    Toxicon : official journal of the International Society on Toxinology, 2004, Volume: 43, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcineurin Inhibitors; Crotoxin; Cyclosporine; Diclofenac; Drug Antagonism; Enzyme Inhibitors; Muscle, Skeletal; Necrosis; Rats; Rats, Wistar

2004
Increased risk of thrombotic microangiopathy in patients receiving a cyclosporin-sirolimus combination.
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2004, Volume: 4, Issue:6

    Topics: Adult; Angiogenesis Inhibitors; Apoptosis; Cells, Cultured; Cohort Studies; Cyclosporine; Drug Therapy, Combination; Endothelium, Vascular; Graft Rejection; Humans; Immunosuppressive Agents; Kidney; Kidney Transplantation; Middle Aged; Mycophenolic Acid; Necrosis; Neovascularization, Pathologic; Pancreas Transplantation; Risk Factors; Sirolimus; Thrombosis

2004
Augmentation of ischemia/reperfusion injury to endothelial cells by cyclosporin A.
    The American surgeon, 2004, Volume: 70, Issue:5

    Topics: Analysis of Variance; Animals; Apoptosis; Calcineurin Inhibitors; Cell Count; Cell Line, Transformed; Cell Survival; Cells, Cultured; Coloring Agents; Cyclosporine; Endothelial Cells; Graft Rejection; Immunosuppressive Agents; Ischemia; Mice; Necrosis; Reperfusion Injury; Tacrolimus; Time Factors; Trypan Blue

2004
Cyclophilin-D promotes the mitochondrial permeability transition but has opposite effects on apoptosis and necrosis.
    The Biochemical journal, 2004, Oct-01, Volume: 383, Issue:Pt 1

    Topics: Amino Acid Sequence; Animals; Apoptosis; Caspases; Cell Line; Cyclophilins; Cyclosporine; Fluorescent Dyes; Intracellular Membranes; Ion Channels; Mitochondria; Mitochondrial ADP, ATP Translocases; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Molecular Sequence Data; Necrosis; Onium Compounds; Organometallic Compounds; Organophosphorus Compounds; Peptidyl-Prolyl Isomerase F; Permeability; Rats; Recombinant Proteins

2004
Protection by cyclosporin A of mitochondrial and cellular functions during a cold preservation-warm reperfusion of rat liver.
    European journal of pharmacology, 2004, Jul-14, Volume: 495, Issue:2-3

    Topics: Animals; Apoptosis; Calcium; Caspase 3; Caspase 9; Caspases; Cells, Cultured; Cold Temperature; Cyclosporine; Cytochromes c; Hepatocytes; In Vitro Techniques; Isotonic Solutions; Liver; Male; Mitochondria, Liver; Mitochondrial Swelling; Necrosis; Rats; Rats, Wistar; Reperfusion; Succinic Acid; Temperature; Time Factors

2004
Mitochondrial permeability transition in acetaminophen-induced necrosis and apoptosis of cultured mouse hepatocytes.
    Hepatology (Baltimore, Md.), 2004, Volume: 40, Issue:5

    Topics: Acetaminophen; Adenosine Triphosphate; Analgesics, Non-Narcotic; Animals; Apoptosis; Caspase 3; Caspases; Cell Death; Cells, Cultured; Cyclosporine; Drug Synergism; Fructose; Glycine; Hepatocytes; Immunosuppressive Agents; Ion Channels; Male; Mice; Mice, Inbred Strains; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Necrosis; Time Factors

2004
Cooling to 10 degrees C and treatment with Cyclosporine A improve cerebral recovery following prolonged hypothermic circulatory arrest in a chronic porcine model.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2005, Volume: 27, Issue:1

    Topics: Animals; Apoptosis; Brain Injuries; Cell Nucleus; Chronic Disease; Cyclosporine; Disease Models, Animal; Electroencephalography; Evoked Potentials; Female; Heart Arrest; Hemodynamics; Hippocampus; Hypothermia, Induced; Intracranial Pressure; Necrosis; Random Allocation; Swine

2005
Postconditioning inhibits mitochondrial permeability transition.
    Circulation, 2005, Jan-18, Volume: 111, Issue:2

    Topics: Animals; Apoptosis; Calcium; Coronary Disease; Cyclosporine; Extracellular Signal-Regulated MAP Kinases; Ion Channel Gating; Ion Channels; Ion Transport; Male; MAP Kinase Signaling System; Membrane Potentials; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Necrosis; Oxidative Stress; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rabbits; Random Allocation; Time Factors

2005
Role of MAPK/ERK in neurotrophin-4 potentiation of necrotic neuronal death.
    Neurochemical research, 2004, Volume: 29, Issue:12

    Topics: Animals; Butadienes; Cell Death; Cells, Cultured; Cyclosporine; Enzyme Activation; Flavonoids; Immunosuppressive Agents; L-Lactate Dehydrogenase; Mice; Mitogen-Activated Protein Kinases; Necrosis; Nerve Growth Factors; Neurons; Nitriles; Phosphorylation; Tetrazolium Salts; Thiazoles

2004
Maintenance immunosuppression use and the associated risk of avascular necrosis after kidney transplantation in the United States.
    Transplantation, 2005, Feb-15, Volume: 79, Issue:3

    Topics: Adult; Cyclosporine; Diabetes Mellitus; Female; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Kidney Transplantation; Lupus Erythematosus, Systemic; Male; Medicare; Middle Aged; Necrosis; Postoperative Complications; Regression Analysis; Sirolimus; Survival Analysis; United States

2005
Enhancement of antimycobacterial activity of macrophages by stabilization of inner mitochondrial membrane potential.
    The Journal of infectious diseases, 2005, Apr-15, Volume: 191, Issue:8

    Topics: Adenosine Triphosphate; Cell Survival; Cyclosporine; Cytochromes c; Humans; Macrophages, Alveolar; Membrane Potentials; Mitochondria; Mycobacterium tuberculosis; Necrosis; Receptors, Purinergic P2

2005
Soluble MHC-peptide complexes induce rapid death of CD8+ CTL.
    Journal of immunology (Baltimore, Md. : 1950), 2005, Jun-01, Volume: 174, Issue:11

    Topics: Antioxidants; Apoptosis; beta-Alanine; Cells, Cultured; Clone Cells; Cyclosporine; Cytotoxicity, Immunologic; Dimerization; Dose-Response Relationship, Immunologic; Growth Inhibitors; H-2 Antigens; Kinetics; Membrane Potentials; Mitochondria; Necrosis; Oligopeptides; Reactive Oxygen Species; Resting Phase, Cell Cycle; Solubility; T-Lymphocytes, Cytotoxic; T-Lymphocytes, Regulatory

2005
Mitochondrial dysfunction is related to necrosis-like programmed cell death induced by A23187 in CEM cells.
    European journal of pharmacology, 2005, Jun-15, Volume: 516, Issue:3

    Topics: Apoptosis; Calcimycin; Calcium; Caspase 3; Caspases; Cell Line, Tumor; Cell Shape; Clonazepam; Cyclosporine; Dose-Response Relationship, Drug; Enzyme Activation; Flow Cytometry; HL-60 Cells; Humans; Intracellular Membranes; Ionophores; Membrane Potentials; Mitochondria; Necrosis; Phospholipases; Proto-Oncogene Proteins c-bcl-2; Thiazepines; Time Factors

2005
Fatal diffuse capillaritis after hematopoietic stem-cell transplantation for dyskeratosis congenita despite low-intensity conditioning regimen.
    Bone marrow transplantation, 2005, Volume: 36, Issue:12

    Topics: Adolescent; Capillaries; Cerebral Hemorrhage; Cyclosporine; Dyskeratosis Congenita; Erythrocyte Transfusion; Esophagus; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunoglobulins, Intravenous; Immunosuppressive Agents; Male; Mucous Membrane; Necrosis; Platelet Transfusion; Time Factors; Transplantation Conditioning; Vascular Diseases

2005
Labeled Schwann cell transplantation: cell loss, host Schwann cell replacement, and strategies to enhance survival.
    Glia, 2006, Volume: 53, Issue:3

    Topics: Alkaline Phosphatase; Animals; Apoptosis; Cell Survival; Cyclosporine; Female; Humans; Immunosuppressive Agents; Necrosis; Nitroblue Tetrazolium; Placenta; Rats; Rats, Inbred F344; Receptor, Nerve Growth Factor; Schwann Cells; Spinal Cord Injuries

2006
Protective effect of oral L-arginine supplementation on cyclosporine induced nephropathy in rats.
    International urology and nephrology, 2005, Volume: 37, Issue:3

    Topics: Animals; Arginine; Atrophy; Cyclosporine; Dietary Supplements; Female; Glomerular Filtration Rate; Immunosuppressive Agents; Kidney Diseases; Kidney Tubules; Necrosis; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley

2005
Lidocaine-induced apoptosis and necrosis in U937 cells depending on its dosage.
    Biomedical research (Tokyo, Japan), 2005, Volume: 26, Issue:6

    Topics: Anesthetics, Local; Caspase 3; Caspase Inhibitors; Caspases; Cell Survival; Cyclosporine; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Lidocaine; Membrane Potentials; Mitochondria; Necrosis; Tetrazolium Salts; U937 Cells

2005
Betanodavirus induces phosphatidylserine exposure and loss of mitochondrial membrane potential in secondary necrotic cells, both of which are blocked by bongkrekic acid.
    Virology, 2006, Apr-10, Volume: 347, Issue:2

    Topics: Apoptosis; Bongkrekic Acid; Cell Line; Cyclosporine; Fish Diseases; Membrane Potentials; Mitochondria; Mitochondria, Liver; Necrosis; Nodaviridae; Phosphatidylserines

2006
Investigation of the effect of hyperbaric oxygen on experimental cyclosporine nephrotoxicity.
    Basic & clinical pharmacology & toxicology, 2006, Volume: 98, Issue:2

    Topics: Animals; Apoptosis; Cyclosporine; Hyperbaric Oxygenation; Kidney; Kidney Diseases; Male; Necrosis; Rats; Rats, Wistar

2006
Apoptosis, necrosis and cell proliferation-inhibition by cyclosporine A in U937 cells (a human monocytic cell line).
    Pharmacological research, 2006, Volume: 53, Issue:3

    Topics: Apoptosis; Aspartic Acid; Caspase 3; Caspase Inhibitors; Caspases; Cell Proliferation; Cell Survival; Cyclosporine; Cytochromes c; Dose-Response Relationship, Drug; Humans; Immunosuppressive Agents; Membrane Potentials; Mitochondria; Necrosis; Protease Inhibitors; Time Factors; U937 Cells

2006
[Odinophagia and cutaneous lesions in patient with cerebral metastases].
    Revista clinica espanola, 2006, Volume: 206, Issue:5

    Topics: Aged; Anticonvulsants; Back; Brain Neoplasms; Cyclosporine; Dermis; Epilepsy; Fatal Outcome; Humans; Immunosuppressive Agents; Male; Mouth Mucosa; Necrosis; Phenytoin; Skin Diseases; Stevens-Johnson Syndrome

2006
Redox-induced apoptosis of human oocytes in resting follicles in vitro.
    Journal of the Society for Gynecologic Investigation, 2006, Volume: 13, Issue:6

    Topics: Adult; Apoptosis; Cell Survival; Cyclosporine; Cytochromes c; Female; Humans; Hydrogen Peroxide; In Situ Nick-End Labeling; Membrane Potentials; Middle Aged; Mitochondrial Membranes; Necrosis; Oocytes; Ovarian Follicle; Oxidation-Reduction; Oxidative Stress; Propidium; Tissue Culture Techniques

2006
Induction of necrotic cell death and mitochondrial permeabilization by heme binding protein 2/SOUL.
    FEBS letters, 2006, Nov-27, Volume: 580, Issue:27

    Topics: Animals; Antineoplastic Agents, Phytogenic; Calcimycin; Calcium; Carrier Proteins; Cyclosporine; Etoposide; Heme-Binding Proteins; Hemeproteins; Humans; Immunosuppressive Agents; Ionophores; Mice; Mitochondria; Mitochondrial Membranes; Necrosis; NIH 3T3 Cells; Permeability; Pregnancy Proteins; Recombinant Proteins

2006
Cardiac glycoside induces cell death via FasL by activating calcineurin and NF-AT, but apoptosis initially proceeds through activation of caspases.
    Apoptosis : an international journal on programmed cell death, 2007, Volume: 12, Issue:2

    Topics: Antibodies; Apoptosis; bcl-X Protein; Calcineurin; Calcineurin Inhibitors; Calcium; Cardenolides; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cell Nucleus; Cyclosporine; Dactinomycin; DNA; Enzyme Activation; Enzyme Inhibitors; Fas Ligand Protein; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Lipids; Membrane Fluidity; Necrosis; NFATC Transcription Factors; Oligopeptides; Protein Transport; Sodium-Potassium-Exchanging ATPase

2007
Cyclosporin A potentiates the cytotoxic effects of methyl methanesulphonate in HL-60 and K562 cells.
    Alternatives to laboratory animals : ATLA, 2007, Volume: 35, Issue:1

    Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caspase 3; Cell Survival; Cyclosporine; DNA Damage; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Synergism; Glutathione; Glutathione Disulfide; HL-60 Cells; Humans; Immunosuppressive Agents; K562 Cells; Methyl Methanesulfonate; Necrosis; Oxidative Stress; RNA, Messenger; RNA, Neoplasm

2007
NIM811, a mitochondrial permeability transition inhibitor, prevents mitochondrial depolarization in small-for-size rat liver grafts.
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2007, Volume: 7, Issue:5

    Topics: Animals; Apoptosis; Cyclosporine; Electrophysiology; Graft Rejection; Hepatocytes; Hyperbilirubinemia; Ion Channels; Liver Regeneration; Liver Transplantation; Male; Mitochondria, Liver; Mitochondrial Proteins; Necrosis; Organ Size; Permeability; Rats; Rats, Inbred Lew; Uncoupling Protein 2

2007
Upregulation of galectin-3 by Corynebacterium kutscheri infection in the rat lung.
    Experimental animals, 2007, Volume: 56, Issue:2

    Topics: Animals; Corynebacterium; Corynebacterium Infections; Cyclosporine; Disease Models, Animal; Galectin 3; Gene Expression Regulation, Bacterial; Immunocompromised Host; Immunosuppressive Agents; Lung; Macrophages, Alveolar; Male; Necrosis; Pneumonia, Pneumococcal; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; RNA, Bacterial; Specific Pathogen-Free Organisms; Spinal Cord Injuries; Staphylococcus aureus

2007
Identification and characterization of cannabinoids that induce cell death through mitochondrial permeability transition in Cannabis leaf cells.
    The Journal of biological chemistry, 2007, Jul-13, Volume: 282, Issue:28

    Topics: Calcium; Cannabis; Caspases; Cell Membrane Permeability; Cyclosporine; DNA Fragmentation; Dronabinol; Mitochondria; Mitochondrial Proteins; Necrosis; Plant Leaves; Plant Proteins

2007
Role of apoptosis in acetaminophen hepatotoxicity.
    Journal of gastroenterology and hepatology, 2007, Volume: 22 Suppl 1

    Topics: Acetaminophen; Animals; Apoptosis; Cell Membrane Permeability; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cyclosporine; Glutathione; Mice; Microscopy, Confocal; Mitochondria, Liver; Necrosis; Oxidative Stress

2007
Cyclosporine A induces senescence in renal tubular epithelial cells.
    American journal of physiology. Renal physiology, 2007, Volume: 293, Issue:3

    Topics: Aging; Apoptosis; Cell Line; Cyclosporine; DNA; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Kidney Tubules; Necrosis; RNA, Messenger; Time Factors

2007
Inhibition of terminal complement components in presensitized transplant recipients prevents antibody-mediated rejection leading to long-term graft survival and accommodation.
    Journal of immunology (Baltimore, Md. : 1950), 2007, Oct-01, Volume: 179, Issue:7

    Topics: Animals; Antibodies; Complement System Proteins; Cyclophosphamide; Cyclosporine; Graft Rejection; Graft Survival; Heart Transplantation; Male; Mice; Necrosis; Proto-Oncogene Proteins c-bcl-2; Skin Transplantation; Survival Rate; Time Factors; Transplantation, Homologous

2007
Opening of mitochondrial permeability transition pore induces hypercontracture in Ca2+ overloaded cardiac myocytes.
    Basic research in cardiology, 2007, Volume: 102, Issue:6

    Topics: Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Cyclosporine; Disease Models, Animal; Enzyme Inhibitors; Male; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Contraction; Myocardial Reperfusion Injury; Myocytes, Cardiac; Necrosis; Organometallic Compounds; Oxidative Stress; Rats; Rats, Sprague-Dawley

2007
Minocycline and N-methyl-4-isoleucine cyclosporin (NIM811) mitigate storage/reperfusion injury after rat liver transplantation through suppression of the mitochondrial permeability transition.
    Hepatology (Baltimore, Md.), 2008, Volume: 47, Issue:1

    Topics: Adenosine Diphosphate; Alanine Transaminase; Animals; Anti-Bacterial Agents; Apoptosis; Calcium; Cyclosporine; Graft Survival; Liver; Liver Transplantation; Male; Minocycline; Mitochondria; Mitochondrial Diseases; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Necrosis; Rats; Rats, Inbred Lew; Reperfusion Injury; Tetracycline

2008
Atypical acute graft-versus-host disease.
    The American Journal of dermatopathology, 2007, Volume: 29, Issue:6

    Topics: Acute Disease; Adult; Bone Marrow Transplantation; Cyclosporine; Erythema; Graft vs Host Disease; Humans; Immunosuppressive Agents; Male; Methotrexate; Necrosis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Skin Diseases; Treatment Outcome

2007
The inositol 1,4,5-trisphosphate receptor is required to signal autophagic cell death.
    Molecular biology of the cell, 2008, Volume: 19, Issue:2

    Topics: Animals; Apoptosis; Autophagy; Cyclosporine; Dictyostelium; Egtazic Acid; Genes, Protozoan; Inositol 1,4,5-Trisphosphate Receptors; Models, Biological; Mutagenesis, Insertional; Mutation; Necrosis; Protozoan Proteins; Signal Transduction; Thapsigargin

2008
Vulnerability of glial cells to hydrogen peroxide in cultured hippocampal slices.
    Brain research, 2008, Mar-10, Volume: 1198

    Topics: Animals; Animals, Newborn; Antioxidants; Brain Ischemia; Cell Death; Cell Survival; Cells, Cultured; Cyclosporine; Dose-Response Relationship, Drug; Energy Metabolism; Fluorescent Dyes; Free Radicals; Hippocampus; Hydrogen Peroxide; Mitochondrial Membranes; Necrosis; Nerve Degeneration; Neuroglia; Organ Culture Techniques; Oxidative Stress; Pyramidal Cells; Rats; Time Factors

2008
Extracellular signal-regulated kinase activation mediates mitochondrial dysfunction and necrosis induced by hydrogen peroxide in renal proximal tubular cells.
    The Journal of pharmacology and experimental therapeutics, 2008, Volume: 325, Issue:3

    Topics: Animals; Cells, Cultured; Cyclosporine; Extracellular Signal-Regulated MAP Kinases; Female; Hydrogen Peroxide; Kidney Tubules, Proximal; Lipid Peroxidation; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Swelling; Necrosis; Oxidants; Phosphorylation; Protein Kinase Inhibitors; Rabbits

2008
Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy.
    Nature medicine, 2008, Volume: 14, Issue:4

    Topics: Animals; Cyclophilins; Cyclosporine; Humans; Laminin; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Mice, Knockout; Mitochondria, Muscle; Mitochondrial Swelling; Muscle, Skeletal; Muscular Dystrophy, Animal; Myocardium; Necrosis; Peptidyl-Prolyl Isomerase F; Sarcoglycans

2008
Acute pancreatitis induced by cyclosporin A under stimulation of pancreas by caerulein.
    Pancreas, 1993, Volume: 8, Issue:6

    Topics: Acute Disease; Amylases; Animals; Ceruletide; Cyclosporine; DNA; Male; Necrosis; Organ Size; Pancreas; Pancreatitis; Proteins; Rats; Rats, Wistar; Vacuoles

1993
Effects of cyclosporine and tacrolimus (FK 506) on acute pancreatitis in mice.
    Archives of surgery (Chicago, Ill. : 1960), 1995, Volume: 130, Issue:1

    Topics: Acute Disease; Animals; Ceruletide; Choline Deficiency; Cyclosporine; Edema; Ethionine; Female; Male; Mice; Necrosis; Pancreatitis; Tacrolimus

1995
Acute necrotico-hemorrhagic pancreatitis after famciclovir prescription.
    Transplantation, 1995, Apr-27, Volume: 59, Issue:8

    Topics: 2-Aminopurine; Acute Disease; Alanine Transaminase; Amylases; Antiviral Agents; Bilirubin; Cyclosporine; DNA, Viral; Famciclovir; Fatal Outcome; Hemorrhage; Hepatitis B; Hepatitis B virus; Humans; Kidney Transplantation; Leukocyte Count; Lipase; Male; Middle Aged; Necrosis; Pancreatitis; Postoperative Complications; Prodrugs

1995
Hamster Greene melanoma in the rabbit eye: immunosuppressive treatment to improve this tumor model.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1994, Volume: 232, Issue:11

    Topics: Animals; Anterior Chamber; Cricetinae; Cyclosporine; Disease Models, Animal; Eye Neoplasms; Female; Immune Tolerance; Immunization; Melanoma; Necrosis; Neoplasm Transplantation; Rabbits

1994
Diagnostic value of [99mTc]MAG-3 imaging in the oligoanuria of the renal transplant patient in the first month after transplantation.
    Transplantation proceedings, 1994, Volume: 26, Issue:1

    Topics: Anuria; Cyclosporine; Evaluation Studies as Topic; Graft Rejection; Humans; Kidney Transplantation; Kidney Tubular Necrosis, Acute; Necrosis; Oliguria; Radionuclide Imaging; Renal Artery Obstruction; Technetium Tc 99m Mertiatide; Thrombosis

1994
Is a late graft biopsy at 3 years after transplantation effective for improving the long-term outcome of renal allografts using cyclosporine?
    Transplantation proceedings, 1994, Volume: 26, Issue:2

    Topics: Azathioprine; Biopsy; Cyclosporine; Drug Therapy, Combination; Endothelium, Vascular; Follow-Up Studies; Glomerulonephritis; Humans; Kidney Transplantation; Necrosis; Retrospective Studies; Steroids; Time Factors; Transplantation, Homologous; Treatment Outcome

1994
A long-term study of allogeneic rat hindlimb transplants immunosuppressed with RS-61443.
    Transplantation, 1993, Volume: 56, Issue:4

    Topics: Animals; Cyclosporine; Graft Rejection; Hindlimb; Immunosuppression Therapy; Immunosuppressive Agents; Major Histocompatibility Complex; Mycophenolic Acid; Necrosis; Rats; Rats, Inbred BN; Rats, Inbred F344; Skin Transplantation; Transplantation, Autologous; Transplantation, Homologous

1993
Long-term follow-up after heart transplantation in Chagas' disease.
    Transplantation proceedings, 1993, Volume: 25, Issue:1 Pt 2

    Topics: Actuarial Analysis; Adrenal Cortex Hormones; Adult; Azathioprine; Chagas Cardiomyopathy; Chagas Disease; Cyclosporine; Follow-Up Studies; Graft Rejection; Heart Transplantation; Humans; Male; Necrosis; Nitroimidazoles; Retrospective Studies; Survival Analysis; Time Factors; Treatment Outcome; Trypanocidal Agents

1993
Effect of immunosuppression on chronic rejection in the rat aortic allograft model.
    Transplantation proceedings, 1993, Volume: 25, Issue:1 Pt 2

    Topics: Animals; Aorta, Thoracic; Chronic Disease; Cyclosporine; Immunosuppressive Agents; Inflammation; Muscle, Smooth, Vascular; Necrosis; Polyenes; Rats; Rats, Inbred Lew; Rats, Inbred WF; Sirolimus; Transplantation, Homologous; Transplantation, Isogeneic

1993
Morphology of ischemic acute renal failure, normal function, and cyclosporine toxicity in cyclosporine-treated renal allograft recipients.
    Kidney international, 1993, Volume: 43, Issue:5

    Topics: Adult; Aged; Cell Membrane; Cyclosporine; Female; Humans; Ischemia; Kidney; Kidney Failure, Chronic; Kidney Transplantation; Kidney Tubules; Male; Microscopy, Electron; Middle Aged; Necrosis; Postoperative Care; Reference Values; Renal Circulation; Transplantation, Homologous

1993
Rejection of the component tissues of limb allografts in rats immunosuppressed with FK-506 and cyclosporine.
    Plastic and reconstructive surgery, 1996, Volume: 97, Issue:1

    Topics: Analysis of Variance; Animals; Biopsy; Bone and Bones; Cartilage, Articular; Cyclosporine; Drug Administration Schedule; Epidermis; Fibrosis; Graft Rejection; Hindlimb; Immunosuppression Therapy; Muscle, Skeletal; Necrosis; Pneumonia, Bacterial; Rats; Rats, Inbred ACI; Rats, Inbred Lew; Tacrolimus

1996
CD28-mediated cytotoxicity of YT natural killer cells on B7-positive targets induces rapid necrotic death independent of granule exocytosis.
    Cellular immunology, 1996, Feb-25, Volume: 168, Issue:1

    Topics: Antibodies, Monoclonal; Apoptosis; B7-1 Antigen; Calcium; CD28 Antigens; Cell Death; Cyclosporine; Cytoplasmic Granules; Cytotoxicity, Immunologic; Exocytosis; Humans; Killer Cells, Natural; Kinetics; Necrosis; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thymoma; Tumor Cells, Cultured

1996
Histological findings in heart grafts after orthotopic pig to baboon cardiac transplantation.
    Transplantation proceedings, 1996, Volume: 28, Issue:2

    Topics: Animals; Animals, Newborn; Cyclosporine; Edema; Female; Graft Rejection; Graft Survival; Guanidines; Heart Transplantation; Hemorrhage; Immunosuppressive Agents; Male; Methotrexate; Necrosis; Papio; Splenectomy; Swine; Tacrolimus; Time Factors; Transplantation, Heterologous

1996
Donor-specific transfusions enhance the immunosuppressive effects of single-dose cyclosporine A and CTLA4-Ig but do not result in long-term graft acceptance in a histoincompatible model of rat lung allograft rejection.
    Transplant immunology, 1996, Volume: 4, Issue:1

    Topics: Abatacept; Animals; Antigens, CD; Antigens, Differentiation; CTLA-4 Antigen; Cyclosporine; Disease Models, Animal; Graft Enhancement, Immunologic; Graft Rejection; Histocompatibility; Immunoconjugates; Immunosuppressive Agents; Lung Transplantation; Necrosis; Rats; Vasculitis

1996
Fulminant hepatitis caused by hepatitis C virus during treatment for multiple sclerosis.
    Journal of gastroenterology, 1996, Volume: 31, Issue:1

    Topics: Anti-Inflammatory Agents; Autopsy; Cyclosporine; Fatal Outcome; Female; Glucocorticoids; Hepatic Encephalopathy; Hepatitis C; Humans; Immunosuppressive Agents; Liver; Liver Failure, Acute; Middle Aged; Multiple Sclerosis; Necrosis; Steroids

1996
Calcineurin and mitochondrial function in glutamate-induced neuronal cell death.
    FEBS letters, 1996, Oct-07, Volume: 394, Issue:3

    Topics: Animals; Apoptosis; Calcineurin; Calmodulin-Binding Proteins; Cells, Cultured; Cerebellum; Cyclosporine; Glutamic Acid; Membrane Potentials; Mitochondria; Necrosis; Neurons; Phosphoprotein Phosphatases; Rats; Tacrolimus

1996
Ceramide induces hepatocyte cell death through disruption of mitochondrial function in the rat.
    Hepatology (Baltimore, Md.), 1997, Volume: 25, Issue:4

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Cell Death; Ceramides; Cyclosporine; Drug Synergism; In Vitro Techniques; Intracellular Membranes; Liver; Male; Membrane Potentials; Mitochondria, Liver; Necrosis; Permeability; Rats; Rats, Sprague-Dawley; Trifluoperazine

1997
Changes in the bioenergetic state of rat hippocampus during 2.5 min of ischemia, and prevention of cell damage by cyclosporin A in hyperglycemic subjects.
    Experimental brain research, 1997, Volume: 114, Issue:1

    Topics: Animals; Brain Ischemia; Cyclosporine; Energy Metabolism; Hippocampus; Hyperglycemia; Male; Mitochondria; Necrosis; Permeability; Prosencephalon; Rats; Rats, Wistar

1997
Effect of immunosuppression on obliterative lesions in a heterotopic large-animal bronchial allograft model.
    Transplantation proceedings, 1997, Volume: 29, Issue:7

    Topics: Animals; Azathioprine; Bronchi; Bronchiolitis Obliterans; Cartilage; Cyclosporine; Drug Therapy, Combination; Fibrosis; Immunosuppressive Agents; Inflammation; Methylprednisolone; Necrosis; Swine; Transplantation, Heterotopic; Transplantation, Homologous

1997
Myocarditis in children with dilated cardiomyopathy: incidence and outcome after dual therapy immunosuppression.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 1997, Volume: 16, Issue:12

    Topics: Anti-Inflammatory Agents; Biopsy; Cardiomyopathy, Dilated; Child, Preschool; Controlled Clinical Trials as Topic; Cyclosporine; Diastole; Echocardiography; Electrocardiography; Follow-Up Studies; Glucocorticoids; Humans; Immunosuppressive Agents; Incidence; Infant; Lymphocytes; Methylprednisolone; Myocardial Contraction; Myocarditis; Myocardium; Necrosis; Prednisolone; Prognosis; Recurrence; Treatment Outcome; Ventricular Function, Left

1997
Effect of different immunosuppressive agents on acute pancreatitis: a comparative study in an improved animal model.
    Transplantation, 1998, Apr-27, Volume: 65, Issue:8

    Topics: Acute Disease; Animals; Azathioprine; Cyclosporine; Immunosuppressive Agents; Male; Muromonab-CD3; Necrosis; Pancreas; Pancreatitis; Prednisolone; Rats; Rats, Sprague-Dawley

1998
Tumor necrosis factor-alpha is expressed by monocytes/macrophages following cardiac microembolization and is antagonized by cyclosporine.
    Basic research in cardiology, 1998, Volume: 93, Issue:2

    Topics: Animals; Coronary Vessels; Cyclosporine; Dexamethasone; Embolism; Fluorescent Antibody Technique, Indirect; Immunohistochemistry; Immunosuppressive Agents; Macrophages; Male; Microcirculation; Monocytes; Myocardial Ischemia; Necrosis; Swine; Time Factors; Tumor Necrosis Factor-alpha

1998
Immunosuppressive effect of the hydrophobic extract of a Chinese herb on rat lung allograft rejection.
    Transplantation proceedings, 1998, Volume: 30, Issue:4

    Topics: Animals; Cyclosporine; Drugs, Chinese Herbal; Graft Rejection; Hemorrhage; Immunosuppressive Agents; Lung Transplantation; Male; Necrosis; Rats; Rats, Inbred BN; Rats, Inbred Lew; Transplantation, Homologous

1998
Antibody to hepatitis B e positive hepatitis induced by withdrawal of steroid therapy for polymyositis: response to interferon-alpha and cyclosporin A.
    Internal medicine (Tokyo, Japan), 1998, Volume: 37, Issue:6

    Topics: Alanine Transaminase; Anti-Inflammatory Agents; Aspartate Aminotransferases; Cyclosporine; DNA, Viral; Female; Hepatitis B; Hepatitis B Antibodies; Hepatitis B virus; Humans; Interferon-alpha; Liver; Liver Failure, Acute; Middle Aged; Necrosis; Polymyositis; Prednisolone

1998
Effects of rapamycin analogue SDZ RAD on obliterative lesions in a porcine heterotopic bronchial allograft model.
    Transplantation proceedings, 1998, Volume: 30, Issue:5

    Topics: Animals; Azathioprine; Bronchi; Bronchiolitis Obliterans; Cartilage; Cyclosporine; Epithelium; Everolimus; Immunosuppressive Agents; Methylprednisolone; Mucous Membrane; Necrosis; Polyenes; Sirolimus; Swine; Transplantation, Heterotopic; Transplantation, Homologous

1998
Apoptosis and necrosis: mechanisms of cell death induced by cyclosporine A in a renal proximal tubular cell line.
    Kidney international, 1998, Volume: 54, Issue:6

    Topics: Animals; Antibodies; Apoptosis; Cell Cycle; Cell Death; Cyclosporine; DNA; fas Receptor; Flow Cytometry; Immunosuppressive Agents; Kidney Tubules, Proximal; Light; LLC-PK1 Cells; Necrosis; Nucleic Acid Synthesis Inhibitors; Protein Synthesis Inhibitors; Scattering, Radiation; Swine

1998
The mitochondrial permeability transition mediates both necrotic and apoptotic death of hepatocytes exposed to Br-A23187.
    Toxicology and applied pharmacology, 1999, Jan-15, Volume: 154, Issue:2

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Calcimycin; Calcium; Cell Survival; Cells, Cultured; Cyclosporine; Fructose; Ionophores; Liver; Male; Microscopy, Confocal; Mitochondria; Necrosis; Permeability; Rats; Rats, Sprague-Dawley

1999
Attenuation of cortical neuronal apoptosis by gangliosides.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:2

    Topics: Animals; Apoptosis; Brain-Derived Neurotrophic Factor; Cells, Cultured; Cerebral Cortex; Culture Media, Serum-Free; Cyclosporine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; G(M1) Ganglioside; Gangliosides; Ionomycin; Mice; N-Methylaspartate; Necrosis; Neurons; Oxidative Stress; Phosphorylation; Protein Kinase Inhibitors; Receptor Protein-Tyrosine Kinases

1999
Rotenone and pyruvate prevent the tert-butylhydroperoxide-induced necrosis of U937 cells and allow them to proliferate.
    FEBS letters, 1999, Aug-20, Volume: 457, Issue:1

    Topics: Apoptosis; Cell Count; Cell Division; Cell Survival; Cyclosporine; DNA Fragmentation; Enzyme Inhibitors; Humans; Kinetics; Necrosis; Pyruvic Acid; Rotenone; tert-Butylhydroperoxide; Time Factors; U937 Cells; Uncoupling Agents

1999
Potentiation by chronic ethanol treatment of the mitochondrial permeability transition.
    Biochemical and biophysical research communications, 1999, Nov-19, Volume: 265, Issue:2

    Topics: Alcoholism; Animals; Apoptosis; bcl-2-Associated X Protein; Calcium; Ceramides; Cyclosporine; Ethanol; Gangliosides; In Vitro Techniques; Liver Diseases, Alcoholic; Male; Mitochondria, Liver; Mitochondrial Swelling; Necrosis; Permeability; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley

1999
Cyclosporin A attenuates acute mitochondrial dysfunction following traumatic brain injury.
    Experimental neurology, 1999, Volume: 160, Issue:1

    Topics: Animals; Brain Injuries; Calcium; Cyclosporine; Drug Evaluation, Preclinical; Intracellular Membranes; Male; Mitochondria; Necrosis; Neuroprotective Agents; Peptidylprolyl Isomerase; Permeability; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Synaptosomes

1999
Up-regulation of multidrug resistance P-glycoprotein via nuclear factor-kappaB activation protects kidney proximal tubule cells from cadmium- and reactive oxygen species-induced apoptosis.
    The Journal of biological chemistry, 2000, Jan-21, Volume: 275, Issue:3

    Topics: Animals; Annexin A5; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cadmium; Cadmium Chloride; Calcium Channel Blockers; Cell Line; Cyclosporine; Cyclosporins; Enzyme Inhibitors; Fluoresceins; Kidney Tubules, Proximal; Kinetics; Necrosis; NF-kappa B; Oxidative Stress; Rats; Rats, Inbred WKY; Reactive Oxygen Species; Time Factors; Up-Regulation; Verapamil

2000
Cortical laminar necrosis caused by immunosuppressive therapy and chemotherapy.
    AJNR. American journal of neuroradiology, 2000, Volume: 21, Issue:3

    Topics: Adolescent; Adult; Antineoplastic Agents; Brain Diseases; Cerebral Cortex; Cyclosporine; Female; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Male; Methotrexate; Middle Aged; Necrosis; Tacrolimus; Tomography, X-Ray Computed; Vincristine

2000
Palmitate-induced apoptosis in cardiomyocytes is mediated through alterations in mitochondria: prevention by cyclosporin A.
    Biochimica et biophysica acta, 2000, May-06, Volume: 1485, Issue:1

    Topics: Animals; Apoptosis; Cell Nucleus; Cell Survival; Cells, Cultured; Chick Embryo; Cyclosporine; Cytochrome c Group; Cytoplasm; DNA; Heart; Intracellular Membranes; Membrane Potentials; Mitochondria; Myocardium; Necrosis; Palmitic Acid

2000
Pyoderma gangrenosum following breast reconstruction.
    British journal of plastic surgery, 2000, Volume: 53, Issue:5

    Topics: Breast Neoplasms; Cyclosporine; Diagnosis, Differential; Female; Humans; Immunosuppressive Agents; Mammaplasty; Middle Aged; Necrosis; Postoperative Complications; Pyoderma Gangrenosum; Surgical Flaps

2000
BNIP3 and genetic control of necrosis-like cell death through the mitochondrial permeability transition pore.
    Molecular and cellular biology, 2000, Volume: 20, Issue:15

    Topics: Apoptosis Inducing Factor; Apoptotic Protease-Activating Factor 1; Bongkrekic Acid; Caspase 3; Caspase 9; Caspases; Cell Death; Cell Line; Cyclosporine; Cytochrome c Group; DNA Fragmentation; Fibroblasts; Flavoproteins; HeLa Cells; Humans; Intracellular Membranes; Membrane Proteins; Mitochondria; Necrosis; Permeability; Proteins; Proto-Oncogene Proteins; Reactive Oxygen Species; Tumor Suppressor Proteins

2000
Mitochondrial Ca(2+)homeostasis in the regulation of apoptotic and necrotic cell deaths.
    Cell calcium, 2000, Volume: 28, Issue:2

    Topics: Animals; Apoptosis; Calcium; Calcium Signaling; Cell Death; Clonazepam; Cyclosporine; Homeostasis; Humans; Male; Mitochondria; Myocardium; Necrosis; Neuroblastoma; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Tumor Cells, Cultured

2000
Nitric-oxide-induced necrosis and apoptosis in PC12 cells mediated by mitochondria.
    Journal of neurochemistry, 2000, Volume: 75, Issue:4

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Azides; Caspase Inhibitors; Caspases; Cell Respiration; Cyclosporine; Cytochrome c Group; Cytosol; Enzyme Inhibitors; Glucose; Lactic Acid; Membrane Potentials; Methacrylates; Mitochondria; Necrosis; Nitric Oxide; Nitric Oxide Donors; Oxygen Consumption; PC12 Cells; Rats; Thiazoles

2000
Ischemia-reperfusion injury in renal transplantation is independent of the immunologic background.
    Kidney international, 2000, Volume: 58, Issue:5

    Topics: Animals; Cell Adhesion Molecules; Cyclosporine; Graft Rejection; Immunosuppressive Agents; Integrin alpha4beta1; Integrins; Ischemia; Kidney; Kidney Transplantation; Lymphocyte Function-Associated Antigen-1; Male; Necrosis; Nephritis; Rats; Rats, Inbred F344; Rats, Inbred Lew; Receptors, Lymphocyte Homing; Renal Circulation; Reperfusion Injury; Selectins; Transplantation, Homologous; Transplantation, Isogeneic

2000
A transient inhibition of mitochondrial ATP synthesis by nitric oxide synthase activation triggered apoptosis in primary cortical neurons.
    Journal of neurochemistry, 2001, Volume: 77, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; Adenosine Triphosphate; Animals; Apoptosis; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cultured; Cerebral Cortex; Cyclosporine; Electron Transport; Electron Transport Complex I; Energy Metabolism; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Isoenzymes; Membrane Potentials; Mitochondria; Models, Biological; NAD; NADH, NADPH Oxidoreductases; Necrosis; Nerve Tissue Proteins; Neurons; Neurotoxins; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oligomycins; omega-N-Methylarginine; Permeability; Rats; Rats, Wistar; Receptors, Glutamate; Rotenone; Single-Blind Method; Succinate Cytochrome c Oxidoreductase

2001
Removal of glutathione produces apoptosis and necrosis in HepG2 cells overexpressing CYP2E1.
    Alcoholism, clinical and experimental research, 2001, Volume: 25, Issue:4

    Topics: Apoptosis; Buthionine Sulfoximine; Caspase 3; Caspases; Cyclosporine; Cytochrome P-450 CYP2E1; Enzyme Inhibitors; Glutathione; Humans; Membrane Potentials; Mitochondria, Liver; Necrosis; Tumor Cells, Cultured

2001
Peroxynitrite promotes mitochondrial permeability transition-dependent rapid U937 cell necrosis: survivors proliferate with kinetics superimposable on those of untreated cells.
    Free radical research, 2001, Volume: 34, Issue:5

    Topics: Antioxidants; Cell Division; Cell Survival; Chromans; Cyclosporine; Dose-Response Relationship, Drug; Humans; Intracellular Membranes; Kinetics; Methionine; Mitochondria; Necrosis; Nitrates; Permeability; U937 Cells

2001
The 4-amino analogue of tetrahydrobiopterin efficiently prolongs murine cardiac-allograft survival.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2001, Volume: 20, Issue:7

    Topics: Animals; Biopterins; Cyclosporine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Graft Survival; Half-Life; Heart Transplantation; Immunosuppressive Agents; Interferon-gamma; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Myocardial Revascularization; Myocardium; Necrosis; Nitric Oxide Synthase; Transplantation Tolerance

2001
Autologous skin transplantation for widespread cutaneous necrosis in secondary antiphospholipid syndrome.
    Annals of the rheumatic diseases, 2001, Volume: 60, Issue:10

    Topics: Adult; Antiphospholipid Syndrome; Cyclosporine; Dermatologic Surgical Procedures; Female; Humans; Immunosuppressive Agents; Necrosis; Prednisone; Reoperation; Skin; Skin Diseases; Skin Transplantation; Treatment Outcome

2001
Zn(2+) induces permeability transition pore opening and release of pro-apoptotic peptides from neuronal mitochondria.
    The Journal of biological chemistry, 2001, Dec-14, Volume: 276, Issue:50

    Topics: Animals; Anti-Bacterial Agents; Apoptosis; Apoptosis Inducing Factor; Bongkrekic Acid; Brain; Calcium; Cations; Cyclosporine; Cytochrome c Group; Cytoplasm; Cytosol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavoproteins; Humans; Immunohistochemistry; Male; Membrane Proteins; Microscopy, Confocal; Mitochondria; Necrosis; Neurons; Rats; Rats, Sprague-Dawley; Time Factors; Trypan Blue; Zinc

2001
1alpha,25-dihydroxyvitamin D3 shows strong and additive immunomodulatory effects with cyclosporine A in rat renal allotransplants.
    Kidney international, 2002, Volume: 61, Issue:1

    Topics: Adjuvants, Immunologic; Animals; Cell Cycle; Cyclosporine; Graft Survival; Hypocalcemia; Immunosuppressive Agents; Interleukin-10; Interleukin-12; Interleukin-2; Interleukin-4; Kidney; Kidney Transplantation; Male; Necrosis; Osteopontin; Rats; Rats, Inbred ACI; Rats, Inbred Lew; Sialoglycoproteins; Vitamin D

2002
Differential modulation of apoptosis and necrosis by antioxidants in immunosuppressed human lymphocytes.
    Toxicology and applied pharmacology, 2002, Apr-15, Volume: 180, Issue:2

    Topics: Acetylcysteine; Adult; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Antioxidants; Apoptosis; Ascorbic Acid; Cyclosporine; Dexamethasone; Glucocorticoids; Humans; Immunosuppressive Agents; In Situ Nick-End Labeling; L-Lactate Dehydrogenase; Lectins, C-Type; Lymphocyte Activation; Lymphocytes; Male; Necrosis; Phytohemagglutinins; Superoxides

2002
HLA-DR expression on tubular cells in kidney transplants.
    Transplantation proceedings, 1992, Volume: 24, Issue:1

    Topics: Biomarkers; Cyclosporine; Graft Rejection; HLA-DR Antigens; Humans; Kidney Transplantation; Kidney Tubules; Necrosis; Prospective Studies; Time Factors

1992
Duodenal gross and microscopic findings after spleno-duodeno-pancreatic allotransplantation in the pig.
    Transplantation proceedings, 1992, Volume: 24, Issue:3

    Topics: Animals; Azathioprine; Cyclosporine; Duodenum; Female; Graft Rejection; Intestinal Mucosa; Necrosis; Pancreas Transplantation; Spleen; Swine; Transplantation, Heterotopic; Transplantation, Homologous

1992
Myopathy associated with HMG-CoA reductase inhibitors (HMGRIs) and cyclosporin A: evaluation in a rat model.
    European heart journal, 1992, Volume: 13 Suppl B

    Topics: Animals; Anticholesteremic Agents; Cyclosporine; Drug Synergism; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Muscles; Muscular Diseases; Necrosis; Pravastatin; Rats; Rats, Inbred Strains; Simvastatin; Structure-Activity Relationship

1992
Acute adenovirus hepatitis in liver transplant recipients.
    The Journal of pediatrics, 1992, Volume: 120, Issue:1

    Topics: Adenovirus Infections, Human; Adenoviruses, Human; Azathioprine; Biliary Atresia; Child, Preschool; Cyclosporine; Hepatitis, Viral, Human; Humans; Infant; Liver Diseases; Liver Transplantation; Necrosis; Prednisone; Time Factors

1992
[Role of macrophages and T-lymphocytes: resistance of guinea pigs to amebic liver infection].
    Archivos de investigacion medica, 1990, Volume: 21 Suppl 1

    Topics: Animals; Cyclosporine; Entamoeba histolytica; Guinea Pigs; Immunity, Cellular; Immunity, Innate; Inflammation; Ischemia; Liver; Liver Abscess, Amebic; Macrophages; Necrosis; T-Lymphocytes

1990