cyclosporine and Left Ventricular Hypertrophy

cyclosporine has been researched along with Left Ventricular Hypertrophy in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (21.74)18.2507
2000's13 (56.52)29.6817
2010's5 (21.74)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Balligand, JL; Bauersachs, J; Clerk, A; De Windt, L; Heymans, S; Hilfiker-Kleiner, D; Hirsch, E; Iaccarino, G; Knöll, R; Leite-Moreira, AF; Lourenço, AP; Mayr, M; Tarone, G; Thum, T; Tocchetti, CG1
Blankenburg, R; Deenen, R; Hackert, K; Lohse, MJ; Schmitt, JP; Seidman, CE; Seidman, JG; Wurster, S1
Baba, HA; Brand, M; Di Marco, GS; Grabner, A; Jacobi, AM; Kentrup, D; Pavenstädt, H; Reuter, S; Tiemann, K; Ting, L1
Bellino, D; Cannella, G; Cassottana, P; Marsano, L; Paoletti, E1
Jovanovic, A; Kosutic, J; Kuzmanovic, M; Pasic, S; Prijic, S1
Csiszar, A; Edwards, JG; Hainsey, T; Sun, S1
Cho, MC; Choi, SY; Kim, DW; Kim, HS; Kim, YG; Kwon, JS; Park, DG; Piao, H; Youn, TJ1
Dong, D; Duan, Y; Duff, HJ; Guo, J; Lees-Miller, JP; Molkentin, JD; Roach, DE; Sheldon, RS; Swirp, SL; Wang, L1
Ahmad, F; Arad, M; Duffy, C; Gannon, J; Lee, RT; Schmitt, JP; Seidman, CE; Seidman, JG; Semsarian, C1
Chen, XJ; Sheng, HZ; Xu, JD; Yang, D; Yang, GP; Zhang, JN1
Amidone, M; Cannella, G; Cassottana, P; Gherzi, M; Paoletti, E; Rolla, D1
Sheng, H; Wu, X; Yang, D; Zhang, J; Zhu, J1
Kowal, RC; Olson, EN; Rusnak, F; Sikkink, RA; Victor, RG; Zhang, W1
Asai, K; Hong, C; McKinsey, TA; Meguro, T; Olson, EN; Takagi, G; Vatner, SF1
Borg, TK; Ding, B; Halloran, PF; Lorell, BH; Price, RL; Weinberg, EO1
Karppanen, H; Krogerus, L; Lähteenmäki, T; Lassila, M; Mervaala, E; Vapaatalo, H; Vaskonen, T1
Chatterjee, K; De Marco, T; Globits, S; Higgins, CB; Klinski, C; Parmley, WW; Sakuma, H; Schwitter, J1
Ahonen, J; Finckenberg, P; Krogerus, L; Lassila, M; Nurminen, ML; Pere, AK; Vapaatalo, H1
Ahonen, J; Karppanen, H; Krogerus, L; Laakso, J; Lindgren, L; Mervaala, EM; Pere, AK; Rauhala, P; Tuomainen, P; Vapaatalo, H1
Asai, K; Bishop, SP; Hong, C; Karoor, VL; Meguro, T; Sadoshima, J; Takagi, G; Vatner, DE; Vatner, SF; Yang, G1
Deng, L; El-Sherif, N; Ganguly, K; Huang, B; Qin, D1
Denney, J; Espino, G; Fitzsimmons, W; Furlong, T; Nash, RA1
Zhang, W1

Reviews

2 review(s) available for cyclosporine and Left Ventricular Hypertrophy

ArticleYear
Targeting myocardial remodelling to develop novel therapies for heart failure: a position paper from the Working Group on Myocardial Function of the European Society of Cardiology.
    European journal of heart failure, 2014, Volume: 16, Issue:5

    Topics: Cell Survival; Cyclosporine; Drugs, Investigational; Heart Failure; Humans; Hypertrophy, Left Ventricular; Myocardial Contraction; Myocytes, Cardiac; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Translational Research, Biomedical; Urea; Ventricular Remodeling

2014
Old and new tools to dissect calcineurin's role in pressure-overload cardiac hypertrophy.
    Cardiovascular research, 2002, Feb-01, Volume: 53, Issue:2

    Topics: A Kinase Anchor Proteins; Adaptor Proteins, Signal Transducing; Adrenergic beta-Agonists; Animals; Animals, Genetically Modified; Body Weight; Calcineurin; Calcineurin Inhibitors; Carrier Proteins; Cyclosporine; DNA-Binding Proteins; Exercise; Gene Transfer Techniques; Hemodynamics; Humans; Hypertension; Hypertrophy, Left Ventricular; Intracellular Signaling Peptides and Proteins; Isoproterenol; Mice; Models, Animal; Muscle Proteins; Myocardium; Phosphoproteins; Rats; Tacrolimus

2002

Trials

4 trial(s) available for cyclosporine and Left Ventricular Hypertrophy

ArticleYear
Effect of everolimus on left ventricular hypertrophy of de novo kidney transplant recipients: a 1 year, randomized, controlled trial.
    Transplantation, 2012, Mar-15, Volume: 93, Issue:5

    Topics: Adult; Aged; Biomarkers; Blood Pressure; Chi-Square Distribution; Cyclosporine; Drug Therapy, Combination; Everolimus; Female; Humans; Hypertrophy, Left Ventricular; Immunosuppressive Agents; Italy; Kidney Transplantation; Linear Models; Male; Middle Aged; Risk Assessment; Risk Factors; Sirolimus; Time Factors; Treatment Outcome; Ultrasonography

2012
ACE inhibitors and persistent left ventricular hypertrophy after renal transplantation: a randomized clinical trial.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2007, Volume: 50, Issue:1

    Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Cyclosporine; Drug Interactions; Female; Follow-Up Studies; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left Ventricular; Immunosuppressive Agents; Kidney Transplantation; Linear Models; Lisinopril; Male; Middle Aged; Tacrolimus

2007
Influence of felodipine on left ventricular hypertrophy and systolic function in orthotopic heart transplant recipients: possible interaction with cyclosporine medication.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 1999, Volume: 18, Issue:10

    Topics: Analysis of Variance; Antihypertensive Agents; Cyclosporine; Diuretics; Drug Interactions; Felodipine; Female; Heart Transplantation; Heart Ventricles; Humans; Hypertrophy, Left Ventricular; Immunosuppressive Agents; Linear Models; Magnetic Resonance Imaging, Cine; Male; Middle Aged; Systole

1999
Assessment of myocardial hypertrophy by echocardiography in adult patients receiving tacrolimus or cyclosporine therapy for prevention of acute GVHD.
    Bone marrow transplantation, 2001, Volume: 28, Issue:12

    Topics: Acute Disease; Adult; Bone Marrow Transplantation; Cyclosporine; Echocardiography; Female; Graft vs Host Disease; Humans; Hypertrophy, Left Ventricular; Immunosuppressive Agents; Male; Middle Aged; Tacrolimus

2001

Other Studies

17 other study(ies) available for cyclosporine and Left Ventricular Hypertrophy

ArticleYear
β-Myosin heavy chain variant Val606Met causes very mild hypertrophic cardiomyopathy in mice, but exacerbates HCM phenotypes in mice carrying other HCM mutations.
    Circulation research, 2014, Jul-07, Volume: 115, Issue:2

    Topics: Amino Acid Substitution; Animals; Cardiac Myosins; Cardiomyopathy, Hypertrophic, Familial; Cyclosporine; Disease Models, Animal; Gene Knock-In Techniques; Genotype; Humans; Hypertrophy, Left Ventricular; Mice; Models, Molecular; Mutation, Missense; Myocardial Contraction; Myosin Heavy Chains; Phenotype; Point Mutation; Protein Conformation; Transcription, Genetic; Ultrasonography; Ventricular Myosins; Ventricular Remodeling

2014
Cardioprotective effect of calcineurin inhibition in an animal model of renal disease.
    European heart journal, 2011, Volume: 32, Issue:15

    Topics: Animals; Calcineurin Inhibitors; Chronic Disease; Cyclosporine; Heart Diseases; Hypertrophy, Left Ventricular; Immunosuppressive Agents; Kidney Diseases; Male; Nephrectomy; Random Allocation; Rats; Rats, Sprague-Dawley; Tacrolimus; Ventricular Remodeling

2011
Severe transient left ventricular pseudohypertrophy during treatment of hemophagocytic lymphohistiocytosis: a case report.
    Journal of pediatric hematology/oncology, 2012, Volume: 34, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cyclosporine; Dexamethasone; Echocardiography; Electrocardiography; Etoposide; Humans; Hypertrophy, Left Ventricular; Infant; Lymphohistiocytosis, Hemophagocytic; Male; Prognosis

2012
Cyclosporin A does not block exercise-induced cardiac hypertrophy.
    Medicine and science in sports and exercise, 2002, Volume: 34, Issue:8

    Topics: Analysis of Variance; Animals; Blotting, Western; Cyclosporine; Disease Models, Animal; Electron Transport Complex IV; Heart Failure; Heart Function Tests; Hypertrophy, Left Ventricular; Male; Physical Conditioning, Animal; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; RNA, Messenger; Treatment Outcome

2002
Effects of the calcineurin dependent signaling pathway inhibition by cyclosporin A on early and late cardiac remodeling following myocardial infarction.
    European journal of heart failure, 2002, Volume: 4, Issue:6

    Topics: Animals; Calcineurin; Calcineurin Inhibitors; Cyclosporine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Echocardiography; Enzyme Inhibitors; Heart Function Tests; Hemodynamics; Hypertrophy, Left Ventricular; Male; Myocardial Infarction; Random Allocation; Rats; Rats, Sprague-Dawley; Recovery of Function; Reference Values; Signal Transduction; Time Factors; Treatment Outcome; Ventricular Remodeling

2002
Overexpression of calcineurin in mouse causes sudden cardiac death associated with decreased density of K+ channels.
    Cardiovascular research, 2003, Volume: 57, Issue:2

    Topics: Animals; Arrhythmias, Cardiac; Calcineurin; Calcineurin Inhibitors; Cyclosporine; Death, Sudden, Cardiac; Electrocardiography; Female; Heart Conduction System; Hypertrophy, Left Ventricular; Long QT Syndrome; Mice; Mice, Inbred ICR; Mice, Transgenic; Patch-Clamp Techniques; Potassium Channels; Survival Rate

2003
Consequences of pressure overload on sarcomere protein mutation-induced hypertrophic cardiomyopathy.
    Circulation, 2003, Sep-02, Volume: 108, Issue:9

    Topics: Animals; Cardiomyopathy, Hypertrophic; Constriction; Cyclosporine; Hemodynamics; Hypertrophy, Left Ventricular; Male; Mice; Mutation; Myosin Heavy Chains; Pressure; RNA; Sarcomeres; Survival Analysis; Ultrasonography

2003
[Role of calcineurin in the progression of cardiac hypertrophy in renovascular hypertensive rats].
    Sheng li xue bao : [Acta physiologica Sinica], 2003, Oct-25, Volume: 55, Issue:5

    Topics: Animals; Calcineurin; Cyclosporine; Hypertension, Renovascular; Hypertrophy, Left Ventricular; Rats; Rats, Sprague-Dawley; RNA, Messenger

2003
Angiotensin-converting enzyme inhibitor suppresses activation of calcineurin in renovascular hypertensive rats.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2007, Volume: 30, Issue:12

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Calcineurin; Calcineurin Inhibitors; Cyclosporine; Heart Ventricles; Hypertension, Renovascular; Hypertrophy, Left Ventricular; Male; Perindopril; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; RNA, Messenger; Signal Transduction

2007
Failure of calcineurin inhibitors to prevent pressure-overload left ventricular hypertrophy in rats.
    Circulation research, 1999, Apr-02, Volume: 84, Issue:6

    Topics: Animals; Aorta, Thoracic; Calcineurin; Calcineurin Inhibitors; Cyclosporine; Disease Models, Animal; Hypertension; Hypertrophy, Left Ventricular; Ligation; Male; Postoperative Complications; Random Allocation; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Tacrolimus

1999
Cyclosporine attenuates pressure-overload hypertrophy in mice while enhancing susceptibility to decompensation and heart failure.
    Circulation research, 1999, Apr-02, Volume: 84, Issue:6

    Topics: Animals; Aorta; Aorta, Abdominal; Aorta, Thoracic; Cyclosporine; Disease Susceptibility; Enzyme Inhibitors; Heart Failure; Hypertension; Hypertrophy, Left Ventricular; Ligation; Male; Mice

1999
Pressure overload induces severe hypertrophy in mice treated with cyclosporine, an inhibitor of calcineurin.
    Circulation research, 1999, Apr-02, Volume: 84, Issue:6

    Topics: Animals; Aorta; Calcineurin; Calcineurin Inhibitors; Cyclosporine; Hypertension; Hypertrophy, Left Ventricular; Ligation; Male; Mice; Mice, Inbred Strains; Myocardium; Random Allocation

1999
Effects of ACE inhibition on cyclosporine A-induced hypertension and nephrotoxicity in spontaneously hypertensive rats on a high-sodium diet.
    Blood pressure, 1999, Volume: 8, Issue:1

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Body Weight; Creatinine; Cyclosporine; Enalapril; Heart Rate; Hypertension; Hypertrophy, Left Ventricular; Kidney; Potassium; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Sodium, Dietary

1999
Comparison of enalapril and valsartan in cyclosporine A-induced hypertension and nephrotoxicity in spontaneously hypertensive rats on high-sodium diet.
    British journal of pharmacology, 2000, Volume: 130, Issue:6

    Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Bradykinin; Bradykinin Receptor Antagonists; Cyclosporine; Dose-Response Relationship, Drug; Drinking; Eating; Electrolytes; Enalapril; Heart Rate; Hypertension; Hypertrophy, Left Ventricular; Kallikreins; Kidney; Kidney Diseases; Male; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; Renin; Sodium, Dietary; Tetrazoles; Urination; Valine; Valsartan

2000
Dietary potassium and magnesium supplementation in cyclosporine-induced hypertension and nephrotoxicity.
    Kidney international, 2000, Volume: 58, Issue:6

    Topics: Acetylglucosaminidase; Animals; Blood Pressure; Bone and Bones; Cholesterol; Cyclosporine; Dopamine; Heart Rate; Hypertension, Renal; Hypertrophy, Left Ventricular; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Tubules, Proximal; Magnesium; Male; Myocardium; Norepinephrine; Potassium, Dietary; Proteinuria; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium, Dietary; Tissue Distribution

2000
Cyclosporine reduces left ventricular mass with chronic aortic banding in mice, which could be due to apoptosis and fibrosis.
    Journal of molecular and cellular cardiology, 2001, Volume: 33, Issue:8

    Topics: Animals; Aorta; Apoptosis; Calcineurin; Calcineurin Inhibitors; Cell Size; Cyclosporine; Enzyme Inhibitors; Fibrosis; Hypertrophy, Left Ventricular; Injections, Subcutaneous; Iron; Ligation; Male; Mice; Mice, Inbred Strains; Myocardium; Time Factors

2001
Calcineurin inhibition ameliorates structural, contractile, and electrophysiologic consequences of postinfarction remodeling.
    Journal of cardiovascular electrophysiology, 2001, Volume: 12, Issue:9

    Topics: Animals; Calcineurin; Calcineurin Inhibitors; Cyclosporine; Enzyme Inhibitors; Hypertrophy, Left Ventricular; Male; Myocardial Infarction; Protein Phosphatase 1; Rats; Rats, Sprague-Dawley; Ventricular Remodeling

2001