cyclosporine has been researched along with Kidney Diseases in 819 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (0.37) | 18.7374 |
| 1990's | 293 (35.78) | 18.2507 |
| 2000's | 327 (39.93) | 29.6817 |
| 2010's | 171 (20.88) | 24.3611 |
| 2020's | 25 (3.05) | 2.80 |
| Authors | Studies |
|---|---|
| Avdeef, A; Tam, KY | 1 |
| Akdogan, N; Aridogan, IA; Bagir, E; Deger, M; Izol, V; Kaplan, HM; Kaya, B | 1 |
| Elshazly, SM; Mahmoud, NM; Rezq, S | 1 |
| Abdul Kadhim, SA; Ghafil, FA; Hadi, NR; Majeed, SA | 1 |
| Honda, A; Kurokawa, M; Masamoto, Y; Matsuda, K; Murakami, D | 1 |
| Azuma, K; Furukawa, T; Iwasaki, T; Kuragano, T; Masumoto, M; Minagawa, Y; Mizusaki, K; Yoshida, M | 1 |
| Aminpour, Y; Ehsanpoor, F; Hosseini, R; Noorbakhsh, S; Otookesh, H; Rahimzadeh, N | 1 |
| Chen, T; Li, X; Rong, R; Wang, J; Wang, X; Yang, C; Zhu, T | 1 |
| Hassan, S; Orentas, M; Patel, N; Rodby, R | 1 |
| Długosz, G; Masajtis-Zagajewska, A; Nowicki, M | 1 |
| Mimaki, M; Nishino, T; Ono, S; Takahashi, K; Tomori, S | 1 |
| Chen, CC; Cheng, CH; Chiu, CH; Chyau, CC; Wu, ZH | 1 |
| Ghafil, FA; Hadi, NR; Kadhim, SAA; Majeed, S; Qassam, H | 1 |
| Gao, J; Wang, C; Wei, W; Wei, X; Yu, J | 1 |
| Abe, M; Endo, M; Fukuda, N; Horikoshi, S; Inoue, T; Mineshige, T; Otsuki, M; Otsuki, T | 1 |
| Can, C; Çavuşoğlu, T; Çelenk, FG; Coşkunsever, D; Duman, S; Olukman, M; Sözmen, E; Ülker, S; Uyanikgil, Y | 1 |
| Blake, SC; Murrell, DF | 1 |
| Dimopoulos, C; Kontzoglou, K; Nikiteas, N; Papadakis, M; Perrea, D | 1 |
| Arnstein, M; Cooper, ME; Coughlan, MT; Forbes, JM; Granata, C; Henstridge, DC; Higgins, GC; Lindblom, RSJ; Nguyen, TV; Snelson, M; Thallas-Bonke, V | 1 |
| Alameddine, R; Bazarbachi, A; El Cheikh, J; Mahfouz, R; Massoud, R; Nasr, R; Zahreddine, A; Zgheib, NK | 1 |
| Asanuma, H; Kanno, Y; Kono, H; Mizuno, R; Morita, S; Nakagawa, K; Oya, M; Shimoda, M; Shinoda, K; Umezawa, K; Yoshida, T | 1 |
| Das, P; Kumar, VL; Vangaveti, S | 1 |
| Bagheri, M; Naderi, R; Niazi, M; Pourjabali, M; Rasmi, Y; Shirpoor, A; Taghizadeh Afshari, A | 1 |
| Borràs, FE; Cañas, L; Carreras-Planella, L; Franquesa, M; Juega, J; Lauzurica, R; Taco, O | 1 |
| Davani-Davari, D; Jafari, M; Karimzadeh, I; Ramzi, M | 1 |
| Bai, Y; Cai, H; Cheriyan, AM; Francis, CE; Gooch, JL; Hoover, RS; King, KN; Linck, VA; Ma, HP; Ume, AC; Williams, CR | 1 |
| Barzaghi, F; Carletti, R; Castoldi, G; Colzani, M; di Gioia, CRT; Ippolito, S; Perseghin, G; Stella, A; Zatti, G; Zerbini, G | 1 |
| Abdulmalik, H; Al Faifi, IS; El Hennawy, HM; El Nazer, W; Fahmy, AE; Faifi, ASA; Kamal, A; Mahedy, A; Safar, O; Zaitoun, MF | 1 |
| Chou, ASY; Gill, A; Jarolimek, W; Nguyen, LT; Pollock, CA; Saad, S; Shi, Y; Wang, R; Yao, Y | 1 |
| Abe, R; Hashida, R; Hirahashi, J; Karigane, D; Kato, J; Kikuchi, T; Koda, Y; Kohashi, S; Mori, T; Nakazato, T; Ogata, M; Okamoto, S; Saburi, M; Sakurai, M; Toyama, T; Yamane, Y; Yuda, S | 1 |
| Diepstra, A; Gard, L; Groen, H; Niesters, HGM; Riezebos-Brilman, A; Sanders, JS; Stegeman, CA; van Doesum, W; van Son, WJ | 1 |
| Jirasiritham, S; Sumethkul, V; Tankee, P; Worawichawong, S | 1 |
| Du, D; Li, Z; Meng, J; Min, B; Sun, J; Sun, W; Tan, X; Wang, W; Yang, F; Zhao, J | 1 |
| Eid, BG; El-Bassossy, HM | 1 |
| Eder, IE; Guenther, J; Loeschenberger, B; Neuwirt, H; Niess, L; Puhr, M; Rudnicki, M; Schwelberger, H; Troppmair, J; Würzner, R | 1 |
| Aurich, B; Baudouin, V; Ha, P; Jacqz-Aigrain, E; Lancia, P; Maisin, A | 1 |
| Chang, YS; Chung, S; Hong, YA; Kim, HS; Kim, M; Kim, S; Koh, ES; Park, CW; Shin, SJ | 1 |
| Huang, J; Qi, H; Weng, G; Yao, X; Ye, X | 1 |
| El-Mas, MM; Helmy, MM; Helmy, MW | 1 |
| Alkhansa, S; Eid, AA; El-Mas, MM; Hammoud, SH; Mahjoub, N; Omar, AG | 1 |
| Boot, L; de Wagenaar, B; Gijzen, L; Hutter, S; Joore, J; Lanz, HL; Masereeuw, R; Ng, CP; Nicolas, A; Nieskens, TTG; Suter-Dick, L; Trietsch, SJ; van den Heuvel, A; van Duinen, V; Vormann, MK; Vriend, J; Vulto, P; Wilmer, M | 1 |
| Li, H; Li, J; Li, Q; Xue, Y | 1 |
| Eberhardt, W; Nasrullah, U; Pfeilschifter, J | 1 |
| Kuca, K; Wu, Q | 1 |
| Arslansoyu Camlar, S; Kavukçu, S; Soylu, A | 1 |
| Chiba, Y; Inoue, CN | 1 |
| Chen, PS; Chen, XT; Chen, YY; Deng, RH; Huang, G; Huang, Y; Li, J; Wang, CX; Wang, ZY; Yang, SC | 1 |
| Ahn, KJ; Choe, YB; Hong, JR; Lee, YW | 1 |
| Abdel-Latif, RG; El-Sheikh, AAK; Morsy, MA | 1 |
| An, WS; Kim, SE; Lee, MH; Lee, SM; Park, Y; Rha, SH; Son, YK | 1 |
| Agellon, LB; Alexander, RT; Chen, XZ; Groenendyk, J; Hu, M; Mengel, M; Michalak, M; Robinson, A; Tang, J; Wang, Q | 1 |
| Abbud-Filho, M; Andrade Nunes, C; Belangero, VMS; Benini, V; Bittencourt, V; Camargo, MF; Cunha, MFMD; de Andrade, LGM; de Souza, VC; Esmeraldo, RM; Facincani, I; Feltran, LS; Fernandes-Charpiot, I; Garcia, CD; Koch Nogueira, P; Laranjo Martins, SP; Moura Diniz Ferreira Leite, C; Palma, L; Penido de Paula, MG; Pestana, JM; Porini Custódio, LF; Prates, LC; Quaresma Mendonça, AC; Ramalho, H; Rohde, R; Russo, ER; Santos, R; Schvartsman, B; Simões Pires, I; Souza Costa, RC; Stopa Martins, SB; Takase, HM; Vasconcelos, MA; Wagner, MB; Watanabe, A | 1 |
| An, WS; Kim, KH; Kim, SE; Lee, SM; Rha, SH; Rho, JH; Son, YK | 1 |
| Abdel-latif, RG; El-Moselhy, MA; Khalifa, MA; Morsy, MA | 1 |
| Bae, SK; Chung, BH; Doh, KC; Heo, SB; Hwang, GH; Jin, L; Lim, SW; Min, KI; Piao, SG; Yang, CW; Zheng, YF | 1 |
| Alves, R; Carvalho, E; Figueiredo, A; Lopes, PC; Mota, A; Parada, B; Reis, F; Rodrigues-Santos, P; Sereno, J; Teixeira, F; Teixeira-Lemos, E; Vala, H | 1 |
| Humphreys, F; Kaur, MR; Raghavendran, RR | 1 |
| Haque, K; Krishnasamy, Y; Lemasters, JJ; Rehman, H; Schnellmann, RG; Thurman, RG; Zhong, Z | 1 |
| Bush, ED; Fabian, E; Herold, M; Kamp, HG; Krennrich, G; Looser, R; Mattes, WB; Mellert, W; Moeller, N; Nadanaciva, S; Naraoka, H; Omura, K; Piccoli, SP; Prokoudine, A; Ruiz-Noppinger, P; Schuppe-Koistinen, I; Strauss, V; van Ravenzwaay, B; Walk, T | 1 |
| Chung, BH; Doh, KC; Heo, SB; Jin, L; Kang, SH; Li, C; Lim, SW; Piao, SG; Yang, CW | 1 |
| Jain, AK; Jain, S; Pohekar, M; Thanki, K | 1 |
| Enya, T; Fujita, S; Izu, A; Miyazawa, T; Nishi, H; Okada, M; Sakata, N; Sugimoto, K; Takemura, T; Wada, N | 1 |
| Nasri, H; Rafieian-Kopaei, M | 1 |
| Riella, LV; Sayegh, MH | 1 |
| Endo, A; Fujinaga, S; Hara, S; Murakami, H; Murano, Y; Nakagawa, M; Ohtomo, Y; Sakuraya, K; Shimizu, T; Someya, T | 1 |
| Bossart, W; Etter, A; Fehr, T; Hässig, A; Müller, N; Roos, M; Schiesser, M; Wüthrich, RP | 1 |
| Azzi, JR; Mallat, SG; Sayegh, MH | 1 |
| Chandramohan, Y; Parameswari, CS | 1 |
| Ivanovski, N; Ivanovski, O; Masin-Spasovska, J; Pavleska-Kuzmanovska, S; Popov, Z; Rambabova-Busljetic, I; Ristovska, V | 1 |
| Ali, RM; El-Gowelli, HM; El-Mas, MM; Helmy, MW | 1 |
| Alloway, RR; Cardi, MA; Krisl, JC; Shields, AR; Woodle, ES | 1 |
| Chang, YS; Choi, BS; Chung, S; Hong, YA; Kim, EN; Kim, MY; Koh, ES; Lim, JH; Park, CW; Shin, SJ | 1 |
| Arn, S; Cina, RA; Hanekamp, JS; Kamano, C; Lee, PW; O'Malley, PE; Sachs, DH; Vagefi, PA; Villani, V; Yamada, K | 1 |
| Chen, CC; Chen, JC; Cheng, CH; Chyau, CC; Shu, KH; Yang, TC | 1 |
| Chen, F; Date, H; Matsuda, Y; Miyata, H | 1 |
| Mao, HX | 1 |
| Chung, BH; Doh, KC; Heo, SB; Jin, J; Jin, L; Lim, SW; Piao, SG; Yang, CW | 1 |
| Alves, R; Carvalho, E; Fernandes, J; Reis, F; Rocha-Pereira, P; Rodrigues-Santos, P; Santos-Silva, A; Sereno, J; Teixeira, F; Vala, H | 1 |
| Fernandes, J; Nunes, S; Reis, F; Rocha-Pereira, P; Rodrigues-Santos, P; Santos-Silva, A; Sereno, J; Teixeira, F; Vala, H | 1 |
| Moattari, A; Mostafavi-Pour, Z; Sardarian, A; Vessal, M; Zal, F | 1 |
| Burdmann, EA; Carlos, CP; Oliani, SM; Sonehara, NM | 1 |
| Amioka, K; Haneda, M; Iwasaki, K; Katayama, A; Kobayashi, T; Kurata, Y; Kuzuya, T; Miwa, Y; Uchida, K; Watarai, Y; Yamada, K | 1 |
| Cao, W; Deng, H; Jiang, S; Lai, X; Liu, X; Ouyang, Z; Wang, Y; Zhong, Z; Zhu, S | 1 |
| Altomare, G; Ayala, F; Bardazzi, F; Bellia, G; Chimenti, S; Colombo, D; Flori, ML; Girolomoni, G; Micali, G; Parodi, A; Peris, K; Vena, GA | 1 |
| Akturk, S; Ates, K; Calayoglu, R; Celebi, ZK; Duman, N; Erturk, S; Keven, K; Kutlay, S; Nergizoglu, G; Sengul, S; Yalcı, AK | 1 |
| Capasso, G; Ciarcia, R; Damiano, S; Florio, S; Garofano, T; Giordano, A; Montagnaro, S; Pagnini, U | 1 |
| Devrim, AK; Essiz, D; Sozmen, M; Sudagidan, M | 1 |
| Chen, YP; Li, M; Rui, HL; Sun, QL | 1 |
| Czechowska, G; Dudka, J; Korolczuk, A; Maciejewski, M; Smolen, A; Widelska, I | 1 |
| Fan, Q; Guan, N; Liu, XY; Pei, P; Ren, YL; Zhang, Y; Zhu, SN | 1 |
| Capasso, G; Ciarcia, R; Damiano, S; Florio, A; Florio, S; Garofano, T; Giordano, A; Mirabella, N; Pagnini, U; Polito, MS; Spagnuolo, M; Squillacioti, C; Zacchia, E | 1 |
| Alves, R; Carvalho, E; Nunes, S; Reis, F; Rocha-Pereira, P; Sereno, J; Teixeira, F; Vala, H | 1 |
| Ateyya, H | 1 |
| Malvezzi, P; Rostaing, L | 1 |
| Lai, Q; Li, T; Mahmoodurrahman, M; Quan, S; Wei, J; Yu, Y; Zhang, C | 1 |
| Amador, CA; Andre-Gregoire, G; Berger, S; Bertocchio, JP; Chatziantoniou, C; Duong Van Huyen, JP; El Moghrabi, S; Jaffe, IZ; Jaisser, F; Placier, S; Rieu, P; Warnock, DG | 1 |
| Balicza-Himer, L; Boros, S; Csohány, R; Fekete, A; Kis-Petik, K; Magda, B; Pap, D; Peti-Peterdi, J; Prókai, Á; Szabó, AJ; Sziksz, E; Vannay, Á | 1 |
| Ding, F; Ding, J; Li, B; Li, X; Wang, S | 1 |
| Attia, GM; Nader, MA | 1 |
| Jeong, HJ; Kim, JH; Kim, PK; Lee, YH; Lim, BJ; Shin, JI | 1 |
| Ahmed, HH; El-Mezayen, HA; Elsherbiny, ES; Rashed, LA; Toson, EA | 1 |
| Lima, F; Mello, ES; Tanigawa, RY; Tannuri, AC; Tannuri, U | 1 |
| Dedinska, I; Krejci, K; Lackova, E; Roland, R; Zadrazil, J; Zilinska, Z | 1 |
| Lerut, E; Naesens, M | 1 |
| Chapman, JR; Nankivell, BJ; OʼConnell, PJ; PʼNg, CH | 1 |
| Bataille, A; Bigé, N; Buob, D; Galichon, P; Hertig, A; Iovanna, JL; Jouanneau, C; Lefevre, G; Legouis, D; Martin, C; Placier, S; Rondeau, E; Vandermeersch, S; Wetzstein, M; Xu-Dubois, YC | 1 |
| Exton, LS; Kirby, B; Mohd Mustapa, MF; Smith, CH; Warren, RB; Weatherhead, SC; Yesudian, PD | 1 |
| Arai, M | 1 |
| Argani, H; Bargahi, N; Dastmalchi, S; Ghasemi, B; Ghazizadeh, T; Ghorbanihaghjo, A; Mesgari Abbasi, M; Mota, A; Nemati, M; Raeisi, S; Rashtchizadeh, N; Vatankhah, AM | 1 |
| Alves, R; Figueiredo, A; Leal, R; Pinto, H | 1 |
| Bogacki, R; Gacka, E; Hyla-Klekot, L; Paradysz, A; Życzkowski, M | 1 |
| Higuchi, T; Horikoshi, H; Hosono, Y; Matsumoto, M; Nakanishi, T; Nakashima, M; Ohsuzu, F; Okada, M; Suzuki, K; Takada, K | 1 |
| Rintala, JM; Rintala, SE; Savikko, J; von Willebrand, E | 1 |
| Bruch, D; Gatto, LA; Kittur, DS; LaSpina, M; Maier, KG; Tripathi, S | 1 |
| Bakr, MA; Fouda, MA; Gheith, OA; Ghoneim, M; Shokeir, AA; Sobh, M | 1 |
| Kasap, B; Kavukcu, S; Kiray, M; Kuralay, F; Sarioglu, S; Soylu, A; Tuğyan, K; Türkmen, M | 1 |
| Choi, BS; Ghee, JY; Han, DH; Kim, J; Kim, SH; Kim, WY; Kim, YS; Song, HK; Yang, CW; Yoon, HE | 1 |
| Bac, P; Dartevelle, P; El Tawil, Z; German-Fattal, M; Hulin, A; Lecerf, F; Maurois, P; Sabbagh, F | 1 |
| El-Agroudy, AE; El-Baz, M; El-Dahshan, KF; Ghoneim, MA; Ismail, AM; Mahmoud, K; Shokeir, AA | 1 |
| Ahn, KO; Cha, JH; Ghee, JY; Kim, J; Kim, JY; Kim, SH; Li, C; Lim, SW; Song, HK; Yang, CW; Yoon, HE | 1 |
| Ahn, KO; Ghee, JY; Han, DH; Han, KH; Handlogten, ME; Kim, HY; Kim, J; Kim, WY; Li, C; Lim, SW; Weiner, ID; Yang, CW | 1 |
| Abouzeinab, HM; Al Alfi, A; Al Mousawi, MS; Al Wakeel, JS; Alorrayed, AS; Dham, RS; Fagir, EA; Mahmoud, TS; Mathew, MC; Shaheen, FA; Shaker, DS; Tarif, NM | 1 |
| Akiyama, T; Koike, H; Nishioka, T; Nose, K | 1 |
| Azarpira, N; Baghban, M; Jamshidzadeh, A; Mohammadi Bardbori, A; Niknahad, H | 1 |
| Kersting, S; Verdonck, LF | 1 |
| Kiuchi, T | 1 |
| Heemann, U; Lutz, J; Türk, TR; Viklicky, O; Vitko, S; Wilde, B; Willenberg, I; Witzke, O | 1 |
| Ballarin, R; Cappelli, G; De Ruvo, N; Di Benedetto, F; Di Sandro, S; Gerunda, GE; Montalti, R; Spaggiari, M | 1 |
| Anglicheau, D; Pallet, N | 1 |
| García-Nieto, V; López-Méndez, M; Luis-Yanes, MI; Martín-Granado, A; Vázquez-Moncholí, C | 1 |
| Banner, NR; Hamour, IM; Lyster, HS; Omar, F; Palmer, A | 1 |
| Nagami, GT; Paige, NM | 1 |
| Kuypers, DR; Naesens, M; Sarwal, M | 1 |
| Auvinen, E; Helanterä, I; Koskinen, P; Lappalainen, M; Lautenschlager, I; Ortiz, F; Räisänen-Sokolowski, A | 1 |
| Ohtsuka, T | 1 |
| Elliott, EN; Gaber, AO; Gaber, LW; Knight, RJ; Patel, SJ | 1 |
| Yang, CW; Yoon, HE | 1 |
| Almenar, L; Arizon, J; Gerosa, G; Hexham, JM; Lehmkuhl, HB; Livi, U; Maccherini, M; Mange, KC; Musumeci, F; Varnous, S; Viganò, M | 1 |
| Bhidayasiri, R; Ling, H | 1 |
| Beckebaum, S; Cicinnati, VR; Gerken, G; Klein, C; Paul, A; Saner, F; Schmitz, K; Sotiropoulos, GC; Varghese, J | 1 |
| Diomedi-Camassei, F; Emma, F; Gianviti, A; Greco, M; Kengne-Wafo, S; Massella, L; Stringini, GR; Vivarelli, M | 1 |
| Banner, NR; Hamour, I; Leaver, N; Lyster, H; Palmer, A | 1 |
| Fujinaga, S; Hara, S; Murakami, H; Ohtomo, Y; Shimizu, T; Someya, T; Umino, D | 1 |
| Chakravarthi, S; Chong, FW; Lee, N; Nagaraja, HS; Thanikachalam, PM | 1 |
| Chen, Z; Hasegawa, T; Okada, K; Okita, Y; Tanaka, Y | 1 |
| Barkun, J; Cantarovich, M; Cecere, R; Giannetti, N; Routy, JP | 1 |
| Fujinaga, S; Hara, S; Ohtomo, Y; Shimizu, T; Someya, T; Umino, D | 1 |
| Salgo, R; Thaçi, D | 1 |
| Aydin, M; Davarci, M; Gökçe, A; Ilhan, S; Oktar, S; Ozkan, OV; Yalçinkaya, FR; Yönden, Z | 1 |
| Elewski, BE; Gottlieb, AB; Lebwohl, M; Rosmarin, DM | 1 |
| Castroagudín, JF; Molina, E; Otero, E; Romero, R; Tomé, S; Varo, E | 1 |
| Dharancy, S; Glowacki, F; Hazzan, M; Noël, C | 1 |
| Epailly, E; Lorho, R | 1 |
| Fernandes, I; Kahan, BD; Knight, R; Lisik, W; Podder, H; Qi, Y; Stepkowski, SM; Wang, ME; Zhang, Y | 1 |
| He, F; Luo, ZM; Ma, L; Tong, JR; Wang, Y | 1 |
| Bohl, DJ; Brennan, DC; Hardinger, KL; Koch, MJ; Storch, GA | 1 |
| Bergh, CH; Bjørtuft, O; Eiskjaer, H; Ekmehag, B; Fagertun, HE; Gude, E; Gullestad, L; Iversen, M; Jansson, K; Mared, L; Mortensen, SA; Riise, GC; Rundqvist, B; Simonsen, S; Solbu, D | 1 |
| Michaluk-Skutnik, J; Taranta-Janusz, K; Wasilewska, A; Zoch-Zwierz, W | 1 |
| Bazan-Perkins, B; Bobadilla, NA; Gamba, G; Lee-Montiel, F; Pérez-Villalva, R; Sánchez-Pozos, K; Uribe, N | 1 |
| Assounga, AG; Maharaj, S | 1 |
| Bae, EH; Choi, C; Kim, IJ; Kim, SW; Lee, J; Ma, SK; Park, JW | 1 |
| Kaplan, B | 1 |
| Al-Otaibi, T; Al-Wahaib, S; El-Sayed, A; Francis, I; Halim, MA; Nair, MP; Nampoory, MR; Said, T | 1 |
| Ghee, JY; Han, DH; Kim, J; Lee, SY; Piao, SG; Song, HK; Song, JH; Yang, CW; Yoon, HE; Yoon, HJ | 1 |
| Reis, FN | 1 |
| Boulinguez, S | 1 |
| Goumenos, DS; Katsoris, PG; Kotsantis, P; Papachristou, E; Papadimitropoulos, A; Vlachojannis, JG | 1 |
| Gelb, SR; Shapiro, RJ; Thornton, WJ | 1 |
| Alfarano, C; Bascands, JL; Chaaya, R; Coatrieux, C; Fares, N; Gue, M; Guilbeau-Frugier, C; Kesteman, AS; Parini, A; Schanstra, JP | 1 |
| El-Dayem, WA; Eladl, M; Elgalaly, H; Kamel, M; Maarouf, AM; Radwan, M; Salem, EA; Salem, NA | 1 |
| Ghee, JY; Han, DH; Kim, S; Kobori, H; Kuro-o, M; Ohashi, N; Piao, S; Song, JH; Yang, CW; Yoon, HE | 1 |
| Altendorf-Hofmann, A; Büchler, P; Friess, H; Kornberg, A; Kornberg, J; Krause, B; Küpper, B; Sappler, A; Thrum, K; Wilberg, J | 1 |
| Boniface, G; Endres, R; Feifel, R; Gimenez y Ribotta, M; Lonjon, N; Perrin, FE; Privat, A | 1 |
| Attia, A; Chibbar, R; Elbarbry, F; Marfleet, T; Ragheb, A; Shoker, A | 1 |
| Choi, BS; Ghee, JY; Han, DH; Ishikawa, N; Kim, J; Kim, SH; Nishijima, F; Obara, K; Piao, S; Song, JH; Yang, CW; Yoon, HE | 1 |
| Chung, JH; Kim, HL; Kim, TH; Lee, BR; Ryu, HH; Shin, BC | 1 |
| Legendre, C; Pallet, N | 1 |
| Beckebaum, S; Cicinnati, VR | 1 |
| Gomonchareonsiri, S; Thamprasert, K; Wongmekiat, O | 1 |
| Baroletti, SA; Gabardi, S | 1 |
| Baba, HA; Brand, M; Di Marco, GS; Grabner, A; Jacobi, AM; Kentrup, D; Pavenstädt, H; Reuter, S; Tiemann, K; Ting, L | 1 |
| Dechêne, A; Gerken, G; Hilgard, P; Kahraman, A; Miller, M; Pütter, C; Ross, SR; Scherag, A; Witzke, O | 1 |
| Abd-Ellah, MF; Mariee, AD | 1 |
| Koskinen, PK; Rintala, JM; Rintala, SE; Savikko, J; von Willebrand, E | 1 |
| Arıca, V; Ilhan, S; Nacar, A; Nazıroğlu, M; Oktar, S; Tutanç, M; Yılmaz, N | 1 |
| Dal Canton, A; Esposito, C; Esposito, V; Fasoli, G; Grosjean, F; Mangione, F; Molinaro, M; Rosso, R; Serpieri, N; Sileno, G; Torreggiani, M; Villa, L | 1 |
| Muthuraman, A; Rana, A; Singh, A; Singla, SK; Sood, S | 1 |
| Bertocchio, JP; Jaisser, F; Warnock, DG | 1 |
| Wang, X; Wang, XT; Wei, M | 1 |
| Jeong, HJ; Kim, JH; Kim, PK; Lee, JS; Lim, BJ; Park, SJ; Shin, JI; Yoon, SJ | 1 |
| Carman, WF; Clancy, M; Geddes, CC; Gunson, R; Mazonakis, E; Thomson, L; Wan, R | 1 |
| Bae, EH; Kim, IJ; Kim, SW; Lee, JU; Ma, SK; Park, CH; Park, JW | 1 |
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| Ding, XQ; Hatori, M; Kokado, Y; Kyakuno, M; Kyo, M; Miki, T; Miyamoto, M; Nakamura, T; Okada, M; Okuyama, A; Takahara, S; Toki, K | 1 |
| Aljama, P; Castillo, DD; Hernández-Herrera, G; López-Rubio, F; Pérez, R | 1 |
| Fujimura, A; Ishii, M; Kobayashi, E; Sugimoto, K; Tsuruoka, S; Yabana, M; Yamauchi, H | 1 |
| Foda, MA; Ghoneim, M; Moustafa, F; Sabry, A; Sally, S; Sobh, M | 1 |
| Boban, D; Bogdanic, V; Cvoriscec, D; Labar, B; Markovic-Glamocak, M; Mrsic, M; Nemet, D; Plavsic, F; Stoos-Veic, T; Sucic, M | 1 |
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| Arribas, I; Cantero, M; Carballo, F; Conejo, JR; de Arriba, G; Parra, T; Rodríguez-Puyol, D; Rodríguez-Puyol, M | 1 |
| Owunwanne, A; Shihab-Eldeen, A; Yacoub, T; Ziada, G | 1 |
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| Batuman, V; Meleg-Smith, S; O'donovan, R; Tesi, RJ; Zarifian, A | 1 |
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| Andoh, TF; Bennett, WM; Shihab, FS; Tanner, AM; Yi, H | 1 |
| Belitsky, P; Kiberd, B; Lawen, J; Mahalati, K | 1 |
| Bennett, WM; de Mattos, AM; Olyaei, AJ | 3 |
| Vanrenterghem, YF | 1 |
| Fleck, C | 1 |
| Herlitz, H; Lindelöw, B | 1 |
| Escousse, A; Gouyon, JB; Guignard, JP; Justrabo, E; Prévot, A; Semama, DS | 1 |
| Chakfe, N; Charloux, A; Geny, B; Hardy, H; Lampert, E; Lonsdorfer, J; Mettauer, B; Piquard, F | 1 |
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| Bittmann, I; Davies, DR; Pardo, J | 1 |
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| MacDonald, AS | 2 |
| Davison, SC; Fry, L; Morris-Jones, R; Powles, AV | 1 |
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| Andoh, TF; Bennett, WM; Shihab, FS; Yi, H | 3 |
| Gouyon, JB; Guignard, JP; Justrabo, E; Prévot, A; Semama, DS; Tendron, A | 1 |
| Brown, H; Fahmy, H; Halloran, PF; Iványi, B; Solez, K; Szenohradszky, P | 1 |
| Dominguez, J; Kiberd, B; MacDonald, AS; Mahalati, K; McAlister, VC | 1 |
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| Hamahira, K; Iijima, K; Kobayashi, A; Nakamura, H; Yoshikawa, N | 1 |
| Anasetti, C; Appelbaum, FR; Deeg, HJ; Doney, K; Furlong, T; Martin, P; Nash, RA; Storb, R; Sullivan, K; Witherspoon, R | 1 |
| Burke, JF; Dunn, SR; Islam, M; Kanalas, J; McCue, P; McGowan, TA; Sharma, K; Zhu, Y | 1 |
| Kyo, M; Morozumi, K; Ota, K; Takahara, S; Takahashi, K; Uchida, K; Wang, JD | 1 |
| Huang, H; Jenkins, JK; Ndebele, K; Salahudeen, AK | 1 |
| Andoh, TF; Bennett, W; Gordon, KL; Hughes, J; Jefferson, JA; Johnson, RJ; Kang, DH; Kim, YG; Mazzali, M; Schreiner, GF; Suga, S | 1 |
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| Rodicio, JL | 1 |
| Gordon, KL; Hughes, J; Jefferson, JA; Johnson, RJ; Kang, DH; Kim, YG; Kivlighn, SD; Lan, HY; Mazzali, M; Suga, S | 1 |
| Arita, S; Hamaguchi, K; Hatakeyama, E; Nakajima, K; Nishimura, M; Otsuka, M; Sakamaki, T; Sakamoto, K; Tanabe, K; Yamada, K | 1 |
| Boots, JM; Christiaans, MH; Kooman, JP; Leunissen, KM; van Der Sande, FM; van Hooff, JP | 1 |
| Dark, JH; de Goede, CG; Hornung, TS; Moghal, NE; O'Brien, C | 1 |
| Geiger, H; Hauser, IA; Koziolek, MJ; Riess, R; Thévenod, F | 1 |
| Ahn, HJ; Bang, BK; Jin, DC; Kim, BS; Kim, J; Kim, YS; Park, JH; Yang, CW | 1 |
| Bernemann, A; Bickeböller, R; Gossmann, J; Raab, HP; Radounikli, A; Schellinski, O; Scheuermann, EH | 1 |
| Bergler-Klein, J; Grimm, M; Laufer, G; Mayer, G; Oberbauer, R; Pirich, C; Regele, H | 1 |
| Atkins, RC; Brown, FG; Bucala, R; Chadban, SJ; Dowling, J; Jose, M; Metz, CN; Nikolic-Paterson, DJ | 1 |
| Burgos, FJ; Mampaso, F; Marcén, R; Ortuño, J; Pascual, J; Rivera, ME; Teruel, JL; Villafruela, JJ | 1 |
| Chan, GZ; Kapoor, M | 1 |
| Bumgardner, GL; Lin, A; Ramos, E; Vincenti, F | 1 |
| Bahr, MJ; Barkmann, A; Böker, KH; Emmanouilidis, N; Klempnauer, J; Manns, MP; Nashan, B; Rosenau, J; Schlitt, HJ; Schmidt, HH; Tusch, G | 1 |
| Bajén, MT; Castelao, A; González, J; Grinyo, JM; Martín-Comín, J; Mora, J; Puchal, R; Roca, M | 1 |
| Belghiti, J; Bernuau, J; Clavien, PA; Durand, F; Heneghan, MA; Selzner, N; Tuttle-Newhall, JE | 1 |
| Kreis, HA; Ponticelli, C | 1 |
| Bianchi, R; Corsetti, G; Rezzani, R; Rodella, L | 1 |
| Alloway, RR; Egidi, MF; Gaber, AO; Gaber, LW; Grewal, HP; Hardinger, KL; Honaker, MR; Shokouh-Amiri, MH; Stratta, RJ; Vera, S | 1 |
| Ayres, I; Dooley, LG; Gaston, RS | 1 |
| Chopra, K; Satyanarayana, PS; Singh, D | 1 |
| Goto, T; Hosogai, N; Seki, J | 1 |
| Braeutigam, M; Christophers, E; Drechsler, S; Faerber, L; Mahrle, G; Meffert, H; Mrowietz, U; Schulze, HJ; Weidinger, G | 1 |
| Choi, YJ; Gabbay, KH; Hodjati, R; Nadkarni, V; Sheikh-Hamad, D; Truong, LD; Wideman, C | 1 |
| Dowling, JP; Egan, MK; Gilbert, RE; Langham, RG; Thomson, NM | 1 |
| Druskis, V; Jankauskiene, A; Laurinavicius, A | 1 |
| Drückler, E; Muscheites, J; Stolpe, HJ; Wigger, M | 1 |
| Broyer, M; Charbit, M; Gagnadoux, MF; Guest, G; Jan, D; Jouvet, P; Lacaille, F; Niaudet, P; Revillon, Y | 1 |
| Benamenyo, JP; Droz, D; Niaudet, P | 1 |
| Bellomo, R; Ronco, C | 1 |
| Baboolal, K; Griffiths, DR; Janezic, A; Jones, GA; Jurewicz, WA | 1 |
| Lassila, M | 1 |
| Berg, U; Ingelman-Sundberg, M; Lytton, SD; Nemeth, A | 1 |
| Csöllei, J; Salplachta, J; Strnadová, V | 1 |
| Anglicheau, D; Bedrossian, J; Desgrandchamps, F; Fornairon, S; Janin, A; Legendre, C; Nochy, D; Passa, P; Rerolle, JP; Thervet, E | 1 |
| West, LJ | 1 |
| Førre, O; Hafström, I; Hannonen, P; Kaltwasser, JP; Kurki, P; Kvien, TK; Laasonen, L; Leirisalo-Repo, M; Manger, B; Prestele, H; Wollheim, FA; Zeidler, HK | 1 |
| Dittmer, ID; Pilmore, HL | 1 |
| Barenbrock, M; Hausberg, M; Hohage, H; Kisters, K; Kosch, M; Rahn, KH; Suwelack, B | 1 |
| Ahn, HJ; Bang, BK; Kim, WY; Kim, YS; Lee, MJ; Li, C; Park, CW; Park, JH; Yang, CW; Yang, JH | 1 |
| Boggi, U; Cuttano, MG; Ferretti, A; Filippi, C; Giovannini, L; Longoni, B; Migliori, M; Mosca, F; Origlia, N; Panichi, V | 1 |
| Fukunaga, M; Ishibashi, M; Kameoka, H; Kawaguchi, N; Kokado, Y; Moutabarrik, A; Onishi, S; Sonoda, T; Takahara, S; Takano, Y | 1 |
| Balcke, P; Gottsauner-Wolf, M; Kurz, RW; Liebisch, B; Marosi, L; Stockenhuber, F | 1 |
| Berland, Y; Chauvet-Monges, AM; Crevat, A; Dussol, B; Elsen, R; Salducci, MD | 1 |
| Keller, F; Offermann, G; Schwarz, A | 1 |
| Shaw, JF | 1 |
| Alton, C; Kahan, BD; Lindholm, A; Welsh, M | 1 |
| Meyrier, A | 1 |
| Kishimoto, T; Kusunose, E; Nakatani, T; Ohyama, A; Tujino, T; Yoshimura, N; Yoshimura, R | 1 |
| Mimran, A; Ribstein, J | 1 |
| Fogo, A; Hellings, SE; Inagami, T; Kon, V | 1 |
| Cole, M; Hyndman, V; Knight, R; Lewis, R; Maddux, M; Mozes, MF; Pollak, R; Scott, E; Van Buren, C; Veremis, S | 1 |
| Korstanje, MJ | 1 |
| Dick, AD; Forrester, JV; Towler, HM; Whiting, P | 1 |
| Sandborn, WJ; Tremaine, WJ | 1 |
| Aguilar, D; Aneiros, J; García Del Moral, R; Montes, A; Navarro, N | 1 |
| Biesenbach, G; Brücke, P; Grafinger, P; Gross, C; Hartl, P; Kaiser, W; Stuby, U; Zazgornik, J | 1 |
| Berardinelli, L; Edefonti, A; Ghio, L; Giani, M; Guerra, L; Mocciaro, A; Tarantino, A; Vegeto, A | 1 |
| Cattran, DC; Maurer, J; Patterson, A; Pei, Y; Zaltzman, JS | 1 |
| Ichiishi, A; Kosaka, S; Kotake, S; Matsuda, H; Minagawa, R; Yoshikawa, K | 1 |
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| Freeman, D; Keown, P; McDonald, J; Petric, R; Stiller, C; Wallace, C | 1 |
| Bennett, WM; Elzinga, LW; Porter, GA; Rosen, S | 1 |
| Kim, T; Kishimoto, T; Kumata, N; Kusunose, E; Maekawa, M; Nakatani, T; Ohyama, A; Tsujino, T; Yoshimura, R | 1 |
| Dalquen, P; Fujimoto, N; Fukunishi, T; Gudat, F; Ichikawa, Y; Kyo, M; Mihatsch, MJ; Nagano, S | 1 |
| Bökenkamp, A; Brodehl, J; Hoyer, PF; Offner, G | 1 |
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| Aupetit, B; Baumelou, A; Benhmida, M; Deray, G; Jacobs, C; Le Hoang, P; Maksud, P | 1 |
| Dressler, DK | 1 |
| Bragoni, M; Ciardi, A; Di Tondo, U; Monge, A; Pecorella, I | 1 |
| Andreu, J; Campistol, JM; Carretero, P; de la Torre, M; Oppenheimer, F; Ricart, MJ; Talbot, R; Vilardell, J | 1 |
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| Abd el-Kader, M; el-Aggan, HA; el-Gebaly, WM | 1 |
| Clunie, GJ; Francis, DM; Millar, RJ; Robertson, AJ; Walker, RG | 1 |
| Feutren, G; Mihatsch, MJ | 1 |
| Fathman, CG; Myers, BD | 1 |
| Burdick, JF; Klassen, DK; Weir, MR | 1 |
| Kim, T; Kishimoto, T; Maekawa, M; Maekawa, T; Nakatani, T; Ohyama, A; Sakamoto, W; Tsujino, T; Yoshimura, R | 1 |
| Bäckman, L; Dati, F; Duraj, FF; Ringdén, O | 1 |
| Belzer, FO; Fox, BC; Kuntz, J; Maki, DG; Sollinger, HW | 1 |
| Göbel, U; Kettritz, R; Natusch, R; Schneider, W; Schöntube, M; Voigt, B | 1 |
| Bohnenkamp, M; Göbel, U; Kettritz, R; Laske, HR; Müller, V; Natusch, R; Schneider, W | 1 |
| Kawashima, H; Kim, T; Kishimoto, T; Kusunose, E; Maekawa, T; Nakatani, T; Ohyama, A; Sakamoto, W; Tsujino, T; Yoshimura, R | 1 |
| Hartz, PA; Wilson, PD | 1 |
| García, R; Henríquez La Roche, C; Herrera, J; Marín, C; Rodríguez-Iturbe, B; Rubio, L | 1 |
| Halimi, JM; Mimran, A; Mion, C; Mourad, G; Ribstein, J | 1 |
| Aparicio, M; Cambar, J; L'Azou, B; Lakhdar, B; Potaux, L | 1 |
| Chow, AW; Cole, CD; Jewesson, PJ; Kureishi, A; Phillips, GL; Reece, DE; Rubinger, M; Smith, JA | 1 |
| Adorno, D; Casciani, CU; Cervelli, V; Cesarini, A; Filingeri, V; Iacona, A; Orsini, D; Rossetti, A | 1 |
| Gordjani, N; Leonhardt, A; Seyberth, HW; Tönshoff, B | 1 |
| Ding, ZK; Hong, JH; Sumrani, N | 1 |
| Brunner, LJ; LeMaistre, CF; Lopez-Berestein, G; Luke, DR; Yau, JC | 1 |
| Klotz, U | 1 |
| Duff, J; Grant, D; Keown, P; Stiller, C; Wallace, C; Zhong, R | 1 |
| Chen, C; Khawar, M; Lancman, I; Pomrantz, A; Tejani, A | 1 |
| Baldwin, JC; Billingham, ME; Jamieson, SW; Ogunnaike, HO; Porter, KA; Starkey, TD | 1 |
120 review(s) available for cyclosporine and Kidney Diseases
| Article | Year |
|---|---|
The association between adult-onset Still's disease and collapsing glomerulopathy: a case report.
Topics: Adolescent; Adult; Cyclosporine; Female; Fever; Humans; Kidney Diseases; Kidney Failure, Chronic; Losartan; Prednisone; Still's Disease, Adult-Onset | 2022 |
Role of cyclosporin A in the treatment of kidney disease and nephrotoxicity.
Topics: Cyclosporine; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation | 2023 |
Monitoring trough levels in cyclosporine for atopic dermatitis: A systematic review.
Topics: Child; Cyclosporine; Dermatitis, Atopic; Drug Administration Schedule; Drug Monitoring; Humans; Immunosuppressive Agents; Kidney Diseases | 2019 |
Calcineurin Inhibitors Nephrotoxicity Prevention Strategies With Stress on Belatacept-Based Rescue Immunotherapy: A Review of the Current Evidence.
Topics: Abatacept; Calcineurin Inhibitors; Cyclosporine; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Postoperative Complications; Tacrolimus | 2021 |
Activation of renal profibrotic TGFβ controlled signaling cascades by calcineurin and mTOR inhibitors.
Topics: Animals; Calcineurin; Calcineurin Inhibitors; Cyclosporine; Fibrosis; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Models, Animal; Reactive Oxygen Species; Signal Transduction; Sirolimus; Tacrolimus; TOR Serine-Threonine Kinases; Transforming Growth Factor beta | 2018 |
Metabolic Pathway of Cyclosporine A and Its Correlation with Nephrotoxicity.
Topics: Animals; Cyclosporine; Cytochrome P-450 Enzyme System; Glucose; Humans; Immunosuppressive Agents; Kidney Diseases; Metabolic Networks and Pathways | 2019 |
Cyclosporine in Pediatric Nephrology.
Topics: Calcineurin Inhibitors; Child; Cyclosporine; Graft Rejection; Humans; Hypertension; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Nephrotic Syndrome; Recurrence; Tacrolimus | 2018 |
T-cell co-stimulatory blockade in transplantation: two steps forward one step back!
Topics: Abatacept; Animals; B7-1 Antigen; B7-2 Antigen; CD28 Antigens; Clinical Trials as Topic; Costimulatory and Inhibitory T-Cell Receptors; Cyclosporine; Disease Susceptibility; Graft Enhancement, Immunologic; Graft Rejection; Graft Survival; Humans; Immunoconjugates; Immunologic Memory; Immunosuppressive Agents; Infections; Kidney Diseases; Lymphocyte Activation; Lymphoproliferative Disorders; Molecular Targeted Therapy; Multicenter Studies as Topic; Postoperative Complications; T-Lymphocytes, Cytotoxic; T-Lymphocytes, Regulatory; Th17 Cells; Transplantation Immunology | 2013 |
[Research progress in mechanisms of drug-induced nephrotoxicity].
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Child; Cyclosporine; Humans; Kidney Diseases | 2014 |
Prevention of nephrotoxicity induced by cyclosporine-A: role of antioxidants.
Topics: Animals; Antioxidants; Cyclosporine; Humans; Kidney Diseases; Oxidative Stress | 2015 |
The safety of calcineurin inhibitors for kidney-transplant patients.
Topics: Calcineurin Inhibitors; Cyclosporine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Everolimus; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Mycophenolic Acid; Tacrolimus | 2015 |
Calcineurin inhibitor nephrotoxicity.
Topics: Acute Disease; Calcineurin Inhibitors; Chronic Disease; Cyclosporine; Diagnosis, Differential; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Risk Assessment; Risk Factors; Tacrolimus | 2009 |
Considerations in sirolimus use in the early and late post-transplant periods.
Topics: Clinical Trials as Topic; Cyclosporine; Drug Therapy, Combination; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Postoperative Period; Sirolimus; Tacrolimus; Time Factors | 2009 |
Established and newly proposed mechanisms of chronic cyclosporine nephropathy.
Topics: Animals; Chronic Disease; Cyclosporine; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Risk Factors; Signal Transduction | 2009 |
Treatment of moderate-to-severe plaque psoriasis.
Topics: Abnormalities, Drug-Induced; Alefacept; Antibodies, Monoclonal; Clinical Trials as Topic; Contraindications; Cyclosporine; Etanercept; Female; Fumarates; Hematologic Diseases; Humans; Hypertension; Immunoglobulin G; Immunosuppressive Agents; Kidney Diseases; Male; Methotrexate; Photochemotherapy; Pregnancy; Pregnancy Complications; Psoriasis; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins; Retinoids; Severity of Illness Index; Tumor Necrosis Factor-alpha | 2009 |
Cyclosporine and psoriasis: 2008 National Psoriasis Foundation Consensus Conference.
Topics: Adolescent; Adult; Animals; Child; Contraindications; Cyclosporine; Drug Interactions; Female; Hepatitis C, Chronic; HIV Infections; Humans; Hypertension; Kidney Diseases; Pregnancy; Psoriasis | 2010 |
The unsolved cyclosporine-induced kidney injury: is paricalcitol a feasible new renoprotective option?
Topics: Bone Density Conservation Agents; Cyclosporine; Ergocalciferols; Fibrosis; Humans; Kidney Diseases; Kidney Transplantation; Protective Agents | 2010 |
[Prescription and surveillance of treatment by a systemic agent or biotherapy in psoriasis].
Topics: Biological Products; Contraindications; Cyclosporine; Drug Administration Routes; Drug Monitoring; Female; Folic Acid; Humans; Immunosuppressive Agents; Kidney Diseases; Latent Tuberculosis; Liver Cirrhosis; Medical History Taking; Methotrexate; Pregnancy; Pregnancy Complications; Psoriasis; Pulmonary Fibrosis; Recurrence; Tumor Necrosis Factor-alpha; Vaccination | 2010 |
Deciphering calcineurin inhibitor nephrotoxicity: a pharmacological approach.
Topics: Animals; Calcineurin; Calcineurin Inhibitors; Cyclosporine; Drug-Related Side Effects and Adverse Reactions; Enzyme Inhibitors; Humans; Kidney Diseases; Tacrolimus | 2010 |
Mineralocorticoid receptor activation and blockade: an emerging paradigm in chronic kidney disease.
Topics: Aldosterone; Animals; Chronic Disease; Cyclosporine; Diabetic Nephropathies; Humans; Kidney Diseases; Kidney Failure, Chronic; Mineralocorticoid Receptor Antagonists; Proteinuria; Receptors, Mineralocorticoid; Renin-Angiotensin System | 2011 |
Mechanisms of renal cell apoptosis induced by cyclosporine A: a systematic review of in vitro studies.
Topics: Animals; Apoptosis; Cyclosporine; Endoplasmic Reticulum Chaperone BiP; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases | 2011 |
Effects of pituitary adenylate cyclase activating polypeptide in the urinary system, with special emphasis on its protective effects in the kidney.
Topics: Animals; Cisplatin; Cyclosporine; Humans; Hypoxia; Ischemia; Kidney; Kidney Diseases; Oxidative Stress; Pituitary Adenylate Cyclase-Activating Polypeptide; Reperfusion; Urinary Tract | 2012 |
Renal fibrosis and proteomics: current knowledge and still key open questions for proteomic investigation.
Topics: Animals; Blood Glucose; Cyclosporine; Diabetic Nephropathies; Fibrosis; Glomerulonephritis; Humans; Hypoxia; Kidney; Kidney Diseases; Kidney Failure, Chronic; Proteomics; Transforming Growth Factor beta | 2011 |
Drug-induced nephrotoxicity in inflammatory bowel disease.
Topics: Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Cyclosporine; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Kidney Diseases; Tumor Necrosis Factor-alpha | 2011 |
[Calcineurin inhibitor nephrotoxicity in renal allografts].
Topics: Acute Disease; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Calcineurin Inhibitors; Chronic Disease; Cyclosporine; Humans; Kidney Diseases; Kidney Glomerulus; Kidney Transplantation; Kidney Tubules; Renin-Angiotensin System; Tacrolimus; Transplantation, Homologous | 2011 |
[Calcineurin inhibitor nephrotoxicity in nephrotic syndrome].
Topics: Adolescent; Calcineurin Inhibitors; Child; Cyclosporine; Diagnosis, Differential; Humans; Kidney Diseases; Kidney Tubules; Male; Nephrotic Syndrome; Risk Factors | 2011 |
[Ischemic tubulointerstitial injury].
Topics: Acute Disease; Antiphospholipid Syndrome; Arteriosclerosis; Calcineurin Inhibitors; Chronic Disease; Contrast Media; Cyclosporine; Humans; Infarction; Ischemia; Kidney Cortex Necrosis; Kidney Diseases; Renal Artery | 2011 |
Immunotherapy in renal diseases.
Topics: Adrenal Cortex Hormones; Antibodies, Monoclonal, Murine-Derived; Azathioprine; Cyclophosphamide; Cyclosporine; Humans; Immunosuppressive Agents; Kidney Diseases; Methotrexate; Plasmapheresis; Prognosis; Recurrence; Rituximab | 2012 |
Mechanisms of cyclosporine-induced renal cell apoptosis: a systematic review.
Topics: Animals; Apoptosis; Cyclosporine; Humans; Immunosuppressive Agents; Kidney Diseases | 2013 |
Antioxidant nutrients protect against cyclosporine A nephrotoxicity.
Topics: Animals; Antioxidants; Ascorbic Acid; Cyclosporine; Glomerular Filtration Rate; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Lipid Peroxides; Reactive Oxygen Species; Thromboxanes; Vitamin E | 2003 |
[Kidney involvement in rheumatoid arthritis].
Topics: Amyloidosis; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Autopsy; Biopsy; Cyclosporine; Glomerulonephritis; Humans; Kidney; Kidney Diseases; Methotrexate; Nephritis, Interstitial; Penicillamine; Time Factors | 2003 |
Cyclosporine nephrotoxicity.
Topics: Acute Disease; Chronic Disease; Cyclosporine; Drug-Related Side Effects and Adverse Reactions; Humans; Immunosuppressive Agents; Kidney Diseases | 2003 |
Ciclosporin in psoriasis clinical practice: an international consensus statement.
Topics: Consensus; Cyclosporine; Drug Administration Schedule; Guideline Adherence; Humans; Hypertension; Immunosuppressive Agents; Kidney Diseases; Psoriasis; Treatment Outcome | 2004 |
[New molecular mechanisms of nephrotoxicity].
Topics: Acetaminophen; Apoptosis; bcl-X Protein; Caspase 8; Caspases; Cyclosporine; Cysteine Proteinase Inhibitors; Cytokines; Endoplasmic Reticulum; Epithelium; fas Receptor; Humans; Kidney Diseases; Kidney Tubules; Mitochondria; Models, Biological; Proto-Oncogene Proteins c-bcl-2 | 2004 |
[Progress on the research of prevention and treatment of renal transplantation rejection by integrative Chinese and Western medicine].
Topics: Aged; Animals; Cyclosporine; Drugs, Chinese Herbal; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Phytotherapy | 2004 |
The use of extracellular matrix probes and extracellular matrix-related probes for assessing diagnosis and prognosis in renal diseases.
Topics: Biomarkers; Chronic Disease; Cyclosporine; Cytokines; Disease Progression; Drug-Related Side Effects and Adverse Reactions; Extracellular Matrix; Gene Expression; Graft Rejection; Humans; Kidney Diseases; Metalloproteases; Predictive Value of Tests; Tissue Inhibitor of Metalloproteinases | 2004 |
[Endothelin and kidney disease].
Topics: Animals; Aspartic Acid Endopeptidases; Autocrine Communication; Cell Division; Cyclosporine; Drug Design; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-Converting Enzymes; Gene Expression; Glomerular Mesangium; Humans; Kidney Diseases; Metalloendopeptidases; Organophosphonates; Tetrazoles; Vasoconstriction | 2004 |
Chronic cyclosporine nephrotoxicity: new insights and preventive strategies.
Topics: Animals; Chronic Disease; Cyclosporine; Humans; Immunosuppressive Agents; Kidney Diseases; Organ Transplantation | 2004 |
[Cyclosporine].
Topics: Aging; Biomarkers; Chromatography, High Pressure Liquid; Cyclosporine; Dosage Forms; Drug Interactions; Drug Monitoring; Food-Drug Interactions; Humans; Immunoassay; Immunosuppressive Agents; Kidney Diseases; Liver Diseases; Specimen Handling | 2004 |
Immunosuppressive treatment and progression of histologic lesions in kidney allografts.
Topics: Animals; Cyclosporine; Disease Progression; Glomerular Filtration Rate; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Mycophenolic Acid; Risk Factors; Sirolimus; Tacrolimus; Transplantation, Homologous | 2005 |
[Molecular biology in regulation of kidney functions: VEGF (vascular endothelial growth factor)].
Topics: Animals; Cyclosporine; Diabetic Nephropathies; Glomerulonephritis, Membranoproliferative; Hemolytic-Uremic Syndrome; Humans; Kidney; Kidney Diseases; Vascular Endothelial Growth Factor A | 2006 |
[Molecular action mechanisms of the therapeutic agents for kidney diseases: Immunosuppressants].
Topics: Antibodies, Monoclonal; Azathioprine; Basiliximab; Cyclophosphamide; Cyclosporine; Fatty Acids, Monounsaturated; Fingolimod Hydrochloride; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Mycophenolic Acid; Propylene Glycols; Recombinant Fusion Proteins; Ribonucleosides; Sphingosine | 2006 |
Nephrotoxicity of ciclosporin A: short-term gain, long-term pain?
Topics: Acute Disease; Chronic Disease; Clinical Trials as Topic; Cyclosporine; Disease Progression; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Graft Rejection; Graft vs Host Disease; Humans; Immunosuppressive Agents; Kidney Diseases; Postoperative Complications; Sirolimus; Tacrolimus | 2006 |
Treatment strategies in pediatric solid organ transplant recipients with calcineurin inhibitor-induced nephrotoxicity.
Topics: Calcineurin Inhibitors; Child; Cyclosporine; Drug Therapy, Combination; Graft Rejection; Graft Survival; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Kidney Diseases; Mycophenolic Acid; Organ Transplantation; Sirolimus; Tacrolimus | 2006 |
Primer: Histopathology of calcineurin-inhibitor toxicity in renal allografts.
Topics: Calcineurin Inhibitors; Cyclosporine; Humans; Kidney Diseases; Kidney Transplantation; Postoperative Complications; Tacrolimus | 2006 |
Protein biomarkers of nephrotoxicity; a review and findings with cyclosporin A, a signal transduction kinase inhibitor and N-phenylanthranilic acid.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Biomarkers; Cisplatin; Cyclosporine; Drug Design; Gentamicins; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; ortho-Aminobenzoates; Proteomics; Rats; Signal Transduction | 2005 |
The CARI guidelines. Calcineurin inhibitors in renal transplantation: nephrotoxicity and calcineurin inhibitors.
Topics: Calcineurin Inhibitors; Cyclosporine; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Tacrolimus | 2007 |
New insights into the pathophysiology of cyclosporine nephrotoxicity: a role of aldosterone.
Topics: Aldosterone; Animals; Cyclosporine; Humans; Immunosuppressive Agents; Kidney Diseases | 2007 |
Sirolimus therapy following early cyclosporine withdrawal in transplant patients: mechanisms of action and clinical results.
Topics: Clinical Trials as Topic; Cyclosporine; Drug Administration Schedule; Drug Therapy, Combination; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Sirolimus | 2006 |
Multicentric carpal-tarsal osteolysis with nephropathy treated successfully with cyclosporine A: a case report and literature review.
Topics: Carpal Bones; Child; Cyclosporine; Hajdu-Cheney Syndrome; Humans; Kidney Diseases; Male; Tarsal Bones | 2007 |
Sirolimus, the first mTOR inhibitor.
Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Atherosclerosis; Bone Marrow Diseases; Cell Division; Clinical Trials as Topic; Cyclosporine; Graft Rejection; Graft vs Host Disease; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Lymphocyte Subsets; Mice; Multicenter Studies as Topic; Muscle, Smooth, Vascular; Neoplasms; Postoperative Complications; Sirolimus; TOR Serine-Threonine Kinases; Wound Healing | 2006 |
Sirolimus use in de "novo renal" transplantation.
Topics: Adrenal Cortex Hormones; Adult; Animals; Antibodies, Monoclonal; Antilymphocyte Serum; Calcineurin Inhibitors; Child; Cyclosporine; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Europe; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Rats; Registries; Sirolimus; Tacrolimus; United States | 2006 |
[Cordyceps sinensis, a fungi used in the Chinese traditional medicine].
Topics: Animals; Cordyceps; Cyclosporine; Didanosine; Drug Costs; Drugs, Chinese Herbal; Fingolimod Hydrochloride; History, 19th Century; History, 20th Century; History, Ancient; Humans; Kidney Diseases; Larva; Medicine, Chinese Traditional; Moths; Mycology; Oxygen Consumption; Propylene Glycols; Sphingosine | 2007 |
The nephrotoxicity of FK506 as compared with cyclosporine.
Topics: Animals; Cyclosporine; Graft Rejection; Humans; Kidney Diseases; Tacrolimus | 1993 |
The nephrotoxicity of immunosuppressive drugs.
Topics: Animals; Cyclosporine; Humans; Hypertension; Immunosuppressive Agents; Kidney; Kidney Diseases; Polyenes; Rats; Sirolimus; Tacrolimus | 1995 |
Complications of cyclosporin therapy.
Topics: Animals; Cyclosporine; Humans; Immunosuppressive Agents; Kidney Diseases | 1995 |
Morphologic features of cyclosporin nephrotoxicity.
Topics: Animals; Cyclosporine; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation | 1995 |
Nephrotoxicity of xenobiotics.
Topics: Aminoglycosides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclosporine; Ethylene Glycol; Ethylene Glycols; Humans; Kidney Diseases; Lithium; Mercury; Xenobiotics | 1995 |
FK 506: a novel immunosuppressant for treatment of autoimmune disease. Rationale and preliminary clinical experience at the University of Pittsburgh.
Topics: Adult; Animals; Autoimmune Diseases; CD4-Positive T-Lymphocytes; Cholangitis; Cyclosporine; Diabetes Mellitus, Type 1; Digestive System Diseases; Disease Models, Animal; Drug Evaluation; Drug Evaluation, Preclinical; Female; Humans; Kidney Diseases; Male; Mice; Multiple Sclerosis; Nephrotic Syndrome; Psoriasis; Rats; Swine; Tacrolimus | 1993 |
The kidney in liver transplantation.
Topics: Cyclosporine; Glomerular Filtration Rate; Hepatorenal Syndrome; Humans; Intraoperative Period; Kidney; Kidney Diseases; Liver Failure; Liver Transplantation; Postoperative Complications; Preoperative Care; Tacrolimus | 1993 |
Efficacy of cyclosporin A (CyA) in psoriasis: an overview of dose/response, indications, contraindications and side-effects.
Topics: Biopsy; Contraindications; Cyclosporine; Dose-Response Relationship, Drug; Female; Humans; Kidney Diseases; Male; Psoriasis; Recurrence | 1995 |
[Mechanism of kidney disorders due to nephrotoxic substances].
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Contrast Media; Cyclosporine; Drug Hypersensitivity; Humans; Kidney Diseases; Lactams | 1994 |
[Kidney disorders induced by non-steroidal anti-inflammatory agents and immunomodulators].
Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Autoimmunity; Cyclosporine; Gold; Humans; Kidney Diseases; Phenacetin | 1994 |
Physiologic and pathophysiologic roles of endothelin in the kidney.
Topics: Acute Kidney Injury; Animals; Body Water; Cyclosporine; Endothelins; Glomerular Filtration Rate; Heart Failure; Hemodynamics; Homeostasis; Humans; Kidney; Kidney Diseases; Kidney Failure, Chronic; Kidney Glomerulus; Radiation Injuries; Receptors, Endothelin; Renal Circulation; Sodium | 1994 |
Endothelin in kidney disease.
Topics: Animals; Body Water; Cyclosporine; Endothelins; Glomerular Filtration Rate; Hepatorenal Syndrome; Humans; Kidney; Kidney Diseases; Kidney Medulla; Renal Insufficiency; Sodium | 1994 |
Omega 3 fatty acids in renal diseases.
Topics: Chronic Disease; Cyclosporine; Fatty Acids, Omega-3; Glomerulonephritis, IGA; Humans; Hyperlipidemias; Kidney Diseases; Kidney Glomerulus; Lupus Nephritis | 1994 |
[Renal damage in rheumatoid arthritis].
Topics: Adult; Amyloidosis; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cyclosporine; Female; Glomerulonephritis; Gold; Humans; Kidney Diseases; Kidney Failure, Chronic; Male; Methotrexate; Middle Aged; Penicillamine; Vasculitis | 1994 |
[Cyclosporin in autoimmune diseases].
Topics: Adult; Arthritis, Rheumatoid; Autoimmune Diseases; Child; Cyclosporine; Humans; Kidney Diseases; Lupus Erythematosus, Systemic; Nephrotic Syndrome | 1994 |
Endothelin and the human kidney: a potential target for new drugs.
Topics: Animals; Cyclosporine; Endothelins; Humans; Kidney; Kidney Diseases; Peptides, Cyclic; Receptors, Endothelin | 1994 |
Does ciprofloxacin interact with cyclosporine?
Topics: Ciprofloxacin; Clinical Trials as Topic; Cyclosporine; Drug Interactions; Drug Therapy, Combination; Humans; Kidney Diseases | 1994 |
Cyclosporin binding proteins. Identification, distribution, function and relation to FK binding proteins.
Topics: Amino Acid Isomerases; Amino Acid Sequence; Animals; Calcineurin; Calmodulin-Binding Proteins; Carrier Proteins; Cyclosporine; Humans; Immunosuppressive Agents; Kidney Diseases; Lymphocyte Activation; Molecular Sequence Data; Peptidylprolyl Isomerase; Phosphoprotein Phosphatases; Tacrolimus Binding Proteins | 1993 |
Calcium antagonists and the kidney. Implications for renal protection.
Topics: Acute Kidney Injury; Calcium Channel Blockers; Contrast Media; Cyclosporine; Humans; Hypertension; Kidney; Kidney Diseases; Kidney Transplantation; Natriuresis | 1993 |
Cyclosporin A nephropathy in patients with rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Cyclosporine; Humans; Kidney; Kidney Diseases | 1993 |
Essential hypertension: a renal disease? A review and update of the evidence.
Topics: Animals; Cyclosporine; Humans; Hypertension; Kidney Diseases; Kidney Failure, Chronic; Kidney Transplantation; Renal Circulation; Sodium Chloride | 1993 |
Cyclosporine-induced renal dysfunction in experimental animals and humans.
Topics: Animals; Cyclosporine; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Kidney Diseases | 1995 |
Molecular mechanisms of immunosuppression by cyclosporine, FK506, and rapamycin.
Topics: Animals; Calcineurin; Calmodulin-Binding Proteins; Carrier Proteins; Cell Cycle Proteins; Cyclosporine; DNA-Binding Proteins; Heat-Shock Proteins; Humans; Immunosuppressive Agents; Kidney Diseases; Phosphatidylinositol 3-Kinases; Phosphoprotein Phosphatases; Phosphotransferases (Alcohol Group Acceptor); Polyenes; Sirolimus; Tacrolimus; Tacrolimus Binding Proteins; TOR Serine-Threonine Kinases | 1995 |
Alternative cyclosporine metabolic pathways and toxicity.
Topics: Animals; Cyclosporine; Cytochrome P-450 Enzyme System; Drug Evaluation; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Microsomes; Proteins; Tissue Distribution | 1995 |
Toxic effects of immunosuppressive drugs: mechanisms and strategies for controlling them.
Topics: Cyclosporine; Drug Monitoring; Humans; Immunosuppressive Agents; Kidney Diseases; Lymphoproliferative Disorders; Organ Transplantation; Tacrolimus | 1996 |
[Drug-induced kidney damage].
Topics: Analgesics; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Contrast Media; Cyclosporine; Humans; Kidney Diseases; Kidney Function Tests; Kidney Tubular Necrosis, Acute; Nephritis, Interstitial; Tacrolimus | 1996 |
Chronic cyclosporine nephropathy: the Achilles' heel of immunosuppressive therapy.
Topics: Autoimmune Diseases; Bone Marrow Transplantation; Cyclosporine; Heart Transplantation; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Liver Transplantation | 1996 |
Insights into chronic cyclosporine nephrotoxicity.
Topics: Animals; Chronic Disease; Cyclosporine; Drug Administration Schedule; Humans; Immunosuppressive Agents; Kidney Diseases; Rats | 1996 |
[Drug-induced renal disorders in patients with rheumatoid arthritis].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Cyclosporine; Cysteine; Humans; Kidney Diseases; Methotrexate; ortho-Aminobenzoates | 1996 |
Cyclosporine nephropathy: pathophysiology and clinical impact.
Topics: Animals; Cyclosporine; Humans; Immunosuppressive Agents; Kidney Diseases; Organ Transplantation | 1996 |
[Cyclosporine nephrotoxicity (chronic arteriolopathy, glomerulopathy)].
Topics: Chronic Disease; Cyclosporine; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Glomerulus; Vascular Diseases | 1997 |
Cyclosporine nephrotoxicity: implications for dermatology.
Topics: Cyclosporine; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Psoriasis | 1997 |
Initiating Neoral therapy.
Topics: Cyclosporine; Dose-Response Relationship, Drug; Emulsions; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Psoriasis | 1997 |
Chronic cyclosporine nephrotoxicity.
Topics: Autoimmune Diseases; Chronic Disease; Cyclosporine; Heart Transplantation; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation | 1998 |
Use of cytotoxic agents and cyclosporine in the treatment of autoimmune disease. Part 1: rheumatologic and renal diseases.
Topics: Autoimmune Diseases; Cell Survival; Cyclosporine; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Kidney Diseases; Rheumatic Diseases; United States | 1998 |
The nephrotoxicity of new and old immunosuppressive drugs.
Topics: Acute Disease; Animals; Chronic Disease; Cyclosporine; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Prognosis; Sirolimus; Tacrolimus | 1998 |
Cyclosporin nephrotoxicity: pathophysiology and comparison with FK-506.
Topics: Animals; Clinical Trials as Topic; Cyclosporine; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Tacrolimus | 1998 |
Endothelins in hypertension and kidney diseases.
Topics: Acute Kidney Injury; Animals; Contrast Media; Cyclosporine; Diabetic Nephropathies; Endothelins; Glomerulonephritis; Humans; Hypertension; Kidney Diseases | 1998 |
Renal toxicity of long-term cyclosporin.
Topics: Autoimmune Diseases; Cyclosporine; Humans; Immunosuppressive Agents; Kidney Diseases | 1999 |
Rapamycin on trial.
Topics: Clinical Trials as Topic; Cyclosporine; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Postoperative Complications; Sirolimus | 1999 |
Immunosuppressant-induced nephropathy: pathophysiology, incidence and management.
Topics: Animals; Clinical Trials as Topic; Cyclosporine; Humans; Immunosuppressive Agents; Incidence; Kidney Diseases; Muromonab-CD3; Organ Transplantation; Tacrolimus | 1999 |
Which calcineurin inhibitor is preferred in renal transplantation: tacrolimus or cyclosporine?
Topics: Arteriosclerosis; Calcineurin Inhibitors; Cyclosporine; Diabetes Mellitus; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Tacrolimus; Time Factors | 1999 |
Nephrotoxicity of immunosuppressive drugs: long-term consequences and challenges for the future.
Topics: Acute Disease; Chronic Disease; Costs and Cost Analysis; Cyclosporine; Diagnosis, Differential; Forecasting; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Monitoring, Physiologic; Risk Factors; Tacrolimus; Time Factors | 2000 |
Renal failure following cardiac transplantation.
Topics: Cyclosporine; Heart Transplantation; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Failure, Chronic; Postoperative Complications; Postoperative Period; Preventive Medicine | 2000 |
Mechanisms of nephrotoxicity.
Topics: Cyclosporine; Humans; Immunosuppressive Agents; Kidney Diseases | 2000 |
Histopathology of calcineurin inhibitor-induced nephrotoxicity.
Topics: Calcineurin Inhibitors; Cyclosporine; Graft Rejection; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases | 2000 |
The clinical impact of nephrotoxicity in liver transplantation.
Topics: Cyclosporine; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Liver Transplantation; Risk Factors; Tacrolimus | 2000 |
The clinical impact of cyclosporine nephrotoxicity in heart transplantation.
Topics: Adult; Cyclosporine; Heart Transplantation; Humans; Kidney Diseases; Kidney Failure, Chronic; Time Factors | 2000 |
Is nonnephrotoxic immunosuppression a possibility?
Topics: Cyclosporine; Graft Rejection; Humans; Immune Tolerance; Immunosuppressive Agents; Kidney Diseases; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Sirolimus; Transplantation Immunology | 2000 |
Management strategies for nephrotoxicity.
Topics: Calcineurin Inhibitors; Cyclosporine; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Tacrolimus | 2000 |
Impact of immunosuppressive therapy on hypertension.
Topics: Area Under Curve; Cyclosporine; Humans; Hypertension; Immunosuppressive Agents; Kidney Diseases; Organ Transplantation; Tacrolimus | 2000 |
Calcium antagonists and renal protection from cyclosporine nephrotoxicity: long-term trial in renal transplantation patients.
Topics: Calcium Channel Blockers; Cyclosporine; Dihydropyridines; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation | 2000 |
Malignancy and renal disease.
Topics: Acute Kidney Injury; Antineoplastic Agents; Bone Marrow Transplantation; Cisplatin; Cyclosporine; Hepatorenal Syndrome; Humans; Kidney Diseases; Methotrexate; Multiple Myeloma; Neoplasms; Renal Replacement Therapy | 2001 |
Causes of late renal allograft loss: chronic allograft dysfunction, death, and other factors.
Topics: Chronic Disease; Cyclosporine; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Transplantation, Homologous | 2001 |
Potential therapeutic interventions to avoid or treat chronic allograft dysfunction.
Topics: Adrenal Cortex Hormones; Calcineurin Inhibitors; Chronic Disease; Cyclosporine; Drug Synergism; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Kidney Diseases; Sirolimus | 2001 |
Cyclosporine in severe psoriasis. Results of a meta-analysis in 579 patients.
Topics: Adolescent; Aged; Aged, 80 and over; Analysis of Variance; Cyclosporine; Dermatologic Agents; Female; Humans; Hypertension; Kidney Diseases; Male; Middle Aged; Psoriasis; Severity of Illness Index | 2001 |
Nephrotoxicity of immunosuppressive drugs: new insight and preventive strategies.
Topics: Calcineurin Inhibitors; Cyclosporine; Endothelin-1; Graft Rejection; Immunosuppressive Agents; Kidney; Kidney Diseases; Mycophenolic Acid; Nitric Oxide; Sirolimus; Tacrolimus; Transforming Growth Factor beta; Transforming Growth Factor beta1; Vasoconstriction | 2001 |
Interaction of cyclosporine A and the renin-angiotensin system; new perspectives.
Topics: Animals; Calcium; Cyclosporine; Humans; Hypertension; Immunosuppressive Agents; Kidney Diseases; Muscle, Smooth, Vascular; Rats; Renin-Angiotensin System | 2002 |
Antihypertensive treatment in renal transplant patients--is there a role for ACE inhibitors?
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Cardiovascular System; Chronic Disease; Cyclosporine; Drug Therapy, Combination; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Postoperative Care | 2001 |
Ultrasound assessment of the problem kidney transplant: a surgical prospective.
Topics: Cyclosporine; Graft Rejection; Humans; Kidney Diseases; Kidney Transplantation; Kidney Tubular Necrosis, Acute; Postoperative Complications; Renal Circulation; Ultrasonography; Ureteral Obstruction | 1992 |
Antiproteinuric and immunological effects of cyclosporin A in the treatment of glomerular diseases.
Topics: Cyclosporine; Glomerulonephritis, IGA; Glomerulonephritis, Membranous; Humans; Immune System; Kidney Diseases; Lupus Nephritis; Nephrotic Syndrome; Proteinuria | 1992 |
Antihypertensive therapy in renal disease and transplantation.
Topics: Acute Kidney Injury; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Cyclosporine; Humans; Hypertension; Kidney Diseases; Kidney Transplantation; Rats | 1992 |
Cyclosporine treatment of inflammatory bowel disease.
Topics: Cholangitis, Sclerosing; Colitis, Ulcerative; Crohn Disease; Cyclosporine; Humans; Hypertrichosis; Kidney Diseases; Paresthesia; Proctocolitis | 1992 |
Cyclosporine: nephrotoxic effects and guidelines for safe use in patients with rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Cyclosporine; Humans; Kidney; Kidney Diseases | 1992 |
Calcium antagonists and the kidney: implications for renal protection.
Topics: Acute Kidney Injury; Animals; Calcium; Cyclosporine; Humans; Kidney; Kidney Diseases; Punctures; Renal Circulation; Vasodilation | 1992 |
Calcium antagonists and the kidney. Implications for renal protection.
Topics: Acute Kidney Injury; Calcium Channel Blockers; Contrast Media; Cyclosporine; Humans; Kidney; Kidney Diseases; Kidney Transplantation; Natriuresis | 1991 |
Prostanoids in paediatric kidney diseases.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Child; Cyclosporine; Eicosanoids; Furosemide; Glucocorticoids; Humans; Kidney Diseases | 1991 |
76 trial(s) available for cyclosporine and Kidney Diseases
| Article | Year |
|---|---|
Everolimus with reduced cyclosporine versus MMF with standard cyclosporine in de novo heart transplant recipients.
Topics: Adrenal Cortex Hormones; Adult; Biopsy; Creatinine; Cyclosporine; Drug Therapy, Combination; Europe; Everolimus; Female; Graft Rejection; Heart Transplantation; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Function Tests; Male; Middle Aged; Mycophenolic Acid; Sirolimus; Time Factors; Treatment Outcome | 2009 |
Improvement of renal function after the switch from a calcineurin inhibitor to everolimus in liver transplant recipients with chronic renal dysfunction.
Topics: Adult; Aged; Biomarkers; Calcineurin Inhibitors; Chronic Disease; Creatinine; Cyclosporine; Drug Administration Schedule; Everolimus; Feasibility Studies; Female; Glomerular Filtration Rate; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Liver Diseases; Liver Transplantation; Male; Middle Aged; Prospective Studies; Sirolimus; Tacrolimus; Time Factors; Treatment Outcome | 2009 |
Everolimus with reduced calcineurin inhibitor in thoracic transplant recipients with renal dysfunction: a multicenter, randomized trial.
Topics: Aged; Calcineurin Inhibitors; Cyclosporine; Drug Therapy, Combination; Everolimus; Female; Glomerular Filtration Rate; Graft Rejection; Graft Survival; Heart Transplantation; Humans; Immunosuppressive Agents; Kidney Diseases; Lung Transplantation; Male; Middle Aged; Scandinavian and Nordic Countries; Sirolimus; Tacrolimus; Time Factors; Treatment Outcome | 2010 |
Prospective study of everolimus with calcineurin inhibitor-free immunosuppression in maintenance heart transplant patients: results at 2 years.
Topics: Biomarkers; Blood Pressure; Calcineurin Inhibitors; Creatinine; Cyclosporine; Drug Administration Schedule; Drug Substitution; Everolimus; Germany; Graft Rejection; Graft Survival; Heart Transplantation; Humans; Immunosuppressive Agents; Kaplan-Meier Estimate; Kidney; Kidney Diseases; Lipids; Prospective Studies; Sirolimus; Time Factors; Treatment Outcome | 2011 |
Conversion from cyclosporine to sirolimus in chronic renal allograft dysfunction: a 4-year prospective study.
Topics: Adult; Biomarkers; Chi-Square Distribution; China; Chronic Disease; Creatinine; Cyclosporine; Drug Administration Schedule; Drug Substitution; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Graft Survival; Humans; Immunosuppressive Agents; Intention to Treat Analysis; Kaplan-Meier Estimate; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Mycophenolic Acid; Prospective Studies; Risk Assessment; Risk Factors; Sirolimus; Time Factors; Transplantation, Homologous; Treatment Outcome | 2011 |
[Conversion from calcineurin inhibitors to sirolimus in chronic allograft nephropathy: a 4-year prospective study].
Topics: Adult; Calcineurin Inhibitors; Cyclosporine; Female; Humans; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Prospective Studies; Sirolimus; Tacrolimus | 2011 |
Early withdrawal of cyclosporine A improves 1-year kidney graft structure and function in sirolimus-treated patients.
Topics: Adult; Aged; Chronic Disease; Cyclosporine; Drug Administration Schedule; Female; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Sirolimus; Transplantation, Homologous; Treatment Outcome | 2003 |
Effects of immediate switch from cyclosporine microemulsion to tacrolimus at first acute rejection in renal allograft recipients.
Topics: Adult; Cyclosporine; Disease-Free Survival; Emulsions; Europe; Female; Graft Rejection; Humans; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Prospective Studies; Recurrence; Tacrolimus; Time Factors; Transplantation, Homologous | 2003 |
Relationship between postoperative erythromycin breath test and early morbidity in liver transplant recipients.
Topics: Adult; Anti-Bacterial Agents; Aryl Hydrocarbon Hydroxylases; Breath Tests; Cyclosporine; Cytochrome P-450 CYP3A; Erythromycin; Female; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Kidney Diseases; Liver; Liver Transplantation; Male; Middle Aged; Oxidoreductases, N-Demethylating; Postoperative Complications; Predictive Value of Tests; Tacrolimus | 2003 |
Conversion from cyclosporine to azathioprine at three months reduces the incidence of chronic allograft nephropathy.
Topics: Adult; Azathioprine; Biopsy; Cardiovascular Diseases; Cause of Death; Chronic Disease; Cyclosporine; Dose-Response Relationship, Drug; Female; Graft Survival; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Neoplasms; Patient Compliance; Proteinuria; Risk Factors; Survival Analysis; Time Factors; Transplantation, Homologous | 2003 |
Withdrawal of cyclosporine or tacrolimus after addition of mycophenolate mofetil in patients with chronic allograft nephropathy.
Topics: Adult; Blood Pressure; Body Mass Index; Creatinine; Cyclosporine; Female; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Mycophenolic Acid; Prospective Studies; Random Allocation; Tacrolimus; Time Factors | 2004 |
A randomized controlled trial of immunosuppression conversion for the treatment of chronic allograft nephropathy.
Topics: Chronic Disease; Cyclosporine; Disease Progression; Drug Therapy, Combination; Glomerular Filtration Rate; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Mycophenolic Acid; Tacrolimus; Transplantation, Homologous | 2004 |
Long-term efficacy and safety of mycophenolate mofetil in liver transplant recipients with calcineurin inhibitor-induced renal dysfunction.
Topics: Adult; Aged; Calcineurin Inhibitors; Creatinine; Cyclosporine; Female; Follow-Up Studies; Graft Rejection; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Liver Transplantation; Male; Middle Aged; Mycophenolic Acid; Prospective Studies; Tacrolimus; Time Factors; Treatment Outcome | 2004 |
Is cyclosporine in renal-transplant recipients more effective when given twice a day than in a single daily dose?
Topics: Adult; Area Under Curve; Creatinine; Cyclosporine; Drug Administration Schedule; Emulsions; Female; Graft Survival; Histocompatibility Testing; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged | 2004 |
Use of fenoldopam to control renal dysfunction early after liver transplantation.
Topics: Adult; Antibodies, Monoclonal; Basiliximab; Creatinine; Cyclosporine; Dopamine; Dopamine Agonists; Drug Therapy, Combination; Female; Fenoldopam; Furosemide; Humans; Immunosuppressive Agents; Infusions, Intravenous; Kidney Diseases; Liver Transplantation; Male; Methylprednisolone; Middle Aged; Postoperative Complications; Recombinant Fusion Proteins | 2004 |
Early cyclosporine a withdrawal in kidney-transplant recipients receiving sirolimus prevents progression of chronic pathologic allograft lesions.
Topics: Adolescent; Adult; Aged; Chronic Disease; Cyclosporine; Disease Progression; Female; Humans; Kidney; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Sirolimus; Transplantation, Homologous | 2004 |
Fenoldopam mesylate and renal function in patients undergoing liver transplantation: a randomized, controlled pilot trial.
Topics: Acute Kidney Injury; Adult; Aged; Blood Urea Nitrogen; Blood Volume; Cyclosporine; Diuretics; Dopamine; Dopamine Agonists; Female; Fenoldopam; Furosemide; Hemodynamics; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Function Tests; Liver Transplantation; Male; Mannitol; Middle Aged; Monitoring, Intraoperative; Pilot Projects; Postoperative Complications; Urodynamics | 2004 |
Use of basiliximab and cyclosporine in heart transplant patients with pre-operative renal dysfunction.
Topics: Adult; Antibodies, Monoclonal; Antilymphocyte Serum; Basiliximab; Biomarkers; Creatinine; Cyclosporine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Follow-Up Studies; Graft Rejection; Heart Failure; Heart Transplantation; Humans; Immunosuppressive Agents; Kidney Diseases; Male; Middle Aged; Postoperative Complications; Preoperative Care; Recombinant Fusion Proteins; Renal Insufficiency; Statistics as Topic; Stroke Volume; Time Factors; Treatment Outcome | 2005 |
[Clinical efficacy and T-lymphocyte subset, serum interferon-gamma (IFN-gamma), tumor necrosis factor-alpha (TNF-alpha), interleukin-2(IL-2) levels on treatment of chronic aplastic anemia patients by shenfu injection combined with stanozol and cyclosporin
Topics: Aconitine; Adolescent; Adult; Aged; Anemia, Aplastic; CD4-CD8 Ratio; Cyclosporine; Drug Combinations; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Ginsenosides; Humans; Interferon-gamma; Interleukin-2; Kidney Diseases; Male; Medicine, Chinese Traditional; Middle Aged; Phytotherapy; Stanozolol; Tumor Necrosis Factor-alpha; Yang Deficiency | 2005 |
Donor origin of BK virus in renal transplantation and role of HLA C7 in susceptibility to sustained BK viremia.
Topics: Alleles; BK Virus; Cyclosporine; Disease Susceptibility; DNA Restriction Enzymes; DNA, Viral; Histocompatibility Testing; HLA Antigens; HLA-C Antigens; Humans; Immunoassay; Immunoenzyme Techniques; Immunoglobulin G; Kidney; Kidney Diseases; Kidney Transplantation; Polymerase Chain Reaction; Polyomavirus Infections; Prospective Studies; Sequence Analysis, DNA; Tacrolimus; Time Factors; Viral Load; Viremia | 2005 |
Initial data on basiliximab in critically ill children undergoing heart transplantation.
Topics: Adaptor Proteins, Signal Transducing; Adolescent; Antibodies, Monoclonal; Basiliximab; Calcineurin; Child; Child, Preschool; Cyclosporine; Extracorporeal Membrane Oxygenation; Female; Graft Rejection; Heart Transplantation; Humans; Immunosuppressive Agents; Infant; Kidney; Kidney Diseases; Male; Phosphoproteins; Receptors, Interleukin-2; Recombinant Fusion Proteins; Tacrolimus | 2005 |
Single-dose daily infusion of cyclosporine for prevention of Graft-versus-host disease after allogeneic bone marrow transplantation from HLA allele-matched, unrelated donors.
Topics: Adolescent; Adult; Alleles; Bone Marrow Transplantation; Cyclosporine; Female; Graft vs Host Disease; Hematologic Neoplasms; HLA Antigens; Humans; Hypertension; Kidney Diseases; Male; Middle Aged; Pharmacokinetics; Tissue Donors; Transplantation, Homologous; Treatment Outcome | 2006 |
Five-year results of a randomized, single-center study of tacrolimus vs microemulsion cyclosporine in heart transplant patients.
Topics: Adult; Antihypertensive Agents; Coronary Stenosis; Cyclosporine; Emulsions; Female; Follow-Up Studies; Graft Rejection; Graft Survival; Heart Diseases; Heart Transplantation; Humans; Hypertension; Hypertriglyceridemia; Immunosuppressive Agents; Kidney Diseases; Male; Middle Aged; Survival Analysis; Tacrolimus; Time Factors; Treatment Outcome | 2006 |
Slowing the progression of chronic allograft nephropathy by conversion from cyclosporine to tacrolimus: a randomized controlled trial.
Topics: Adult; Chronic Disease; Cyclosporine; Female; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Tacrolimus; Transplantation, Homologous | 2006 |
Long-term results of kidney transplantation with cyclosporine- and everolimus-based immunosuppression.
Topics: Adult; Aged; Cyclosporine; Drug Therapy, Combination; Everolimus; Female; Follow-Up Studies; Graft Survival; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Sirolimus; Time Factors | 2006 |
Conversion of ciclosporin A to tacrolimus in kidney transplant recipients with chronic allograft nephropathy.
Topics: Adolescent; Adult; Aged; Chronic Disease; Creatinine; Cyclosporine; Female; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Prospective Studies; Tacrolimus | 2006 |
Steroid-free immunosuppression in kidney transplant recipients and prograf monotherapy: an interim analysis of a prospective multicenter trial.
Topics: Adult; Aged; Creatinine; Cyclosporine; Female; Follow-Up Studies; Graft Survival; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Tacrolimus; Transplantation, Homologous | 2006 |
Tolerability of enteric-coated mycophenolate sodium to 1 year in combination with cyclosporine and corticosteroids in renal transplant recipients.
Topics: Adrenal Cortex Hormones; Adult; Cyclosporine; Drug Therapy, Combination; Drug Tolerance; Emulsions; Female; Histocompatibility Testing; Humans; Isoantibodies; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Mycophenolic Acid; Tablets, Enteric-Coated; Tissue Donors | 2006 |
Renal outcome after ciclosporin-induced nephrotoxicity.
Topics: Adult; Aged; Blood Glucose; Colorimetry; Creatinine; Cyclosporine; Female; Follow-Up Studies; Glomerular Filtration Rate; Humans; Immunosuppressive Agents; Kidney Diseases; Male; Middle Aged; Prognosis; Prospective Studies; Uric Acid; Uveitis | 2007 |
Population pharmacokinetics and bayesian estimator of cyclosporine in pediatric renal transplant patients.
Topics: Adolescent; Age Factors; Algorithms; Area Under Curve; Bayes Theorem; Body Weight; Child; Creatinine; Cyclosporine; Female; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Metabolic Clearance Rate; Models, Biological; Retrospective Studies; Tissue Distribution | 2007 |
Amphotericin B dose optimization in children with malignant diseases.
Topics: Adolescent; Amphotericin B; Antifungal Agents; Body Weight; Child; Child, Preschool; Computer Simulation; Creatinine; Cyclosporine; Deoxycholic Acid; Drug Combinations; gamma-Glutamyltransferase; Humans; Immunosuppressive Agents; Infant; Kidney Diseases; Microbial Sensitivity Tests; Models, Biological; Mycoses; Neoplasms; Risk Factors; Urea | 2007 |
Prevention of renal dysfunction and hypertension by amlodipine after heart transplant.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Creatinine; Cyclosporine; Double-Blind Method; Echocardiography; Female; Heart Transplantation; Humans; Hypertension; Immunosuppressive Agents; Kidney Diseases; Lipids; Male; Middle Aged; Ventricular Function, Left | 2007 |
Randomized controlled study comparing reduced calcineurin inhibitors exposure versus standard cyclosporine-based immunosuppression.
Topics: Adult; Calcineurin Inhibitors; Cardiovascular Diseases; Cyclosporine; Drug Therapy, Combination; Female; Graft Rejection; Graft Survival; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Incidence; Kidney; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Proteinuria; Survival Analysis; Tacrolimus | 2007 |
A randomized controlled trial of late conversion from calcineurin inhibitor (CNI)-based to sirolimus-based immunosuppression in liver transplant recipients with impaired renal function.
Topics: Blood Pressure; Calcineurin Inhibitors; Cyclosporine; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Liver Transplantation; Male; Middle Aged; Quality of Life; Sirolimus; Tacrolimus; Time Factors; Treatment Outcome | 2007 |
Renal effects of dietary supplementation with fish oil in cyclosporine-treated liver transplant recipients.
Topics: Adolescent; Adult; Cyclosporine; Dietary Fats, Unsaturated; Double-Blind Method; Fatty Acids; Female; Fish Oils; Glomerular Filtration Rate; Humans; Immunosuppressive Agents; Kidney Diseases; Liver Transplantation; Male; Middle Aged; Placebos; Prospective Studies; Renal Plasma Flow, Effective; Thromboxane B2; Urea | 1995 |
A clinical trial of cyclosporine G in cadaveric renal transplantation.
Topics: Adult; Aged; Cadaver; Cyclosporine; Double-Blind Method; Female; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Function Tests; Kidney Transplantation; Kidney Tubular Necrosis, Acute; Male; Middle Aged; Prospective Studies; Tissue Donors | 1995 |
The effects of cyclosporine and prednisone on serum lipid and (apo)lipoprotein levels in renal transplant recipients.
Topics: Adult; Apolipoproteins; Arteriosclerosis; Azathioprine; Cholesterol, HDL; Cyclosporine; Female; Graft Rejection; Humans; Hyperlipidemias; Hypertension; Kidney Diseases; Kidney Transplantation; Lipids; Lipoproteins; Male; Middle Aged; Obesity; Postoperative Complications; Prednisone; Prospective Studies; Proteinuria; Risk; Risk Factors | 1995 |
FK506 treatment of graft-versus-host disease developing or exacerbating during prophylaxis and therapy with cyclosporin and/or other immunosuppressants. Japanese FK506 BMT Study Group.
Topics: Acute Disease; Adolescent; Adult; Azathioprine; Bone Marrow Transplantation; Child; Chronic Disease; Cyclosporine; Female; Flushing; Graft vs Host Disease; Humans; Immunosuppressive Agents; Kidney Diseases; Male; Methotrexate; Middle Aged; Nausea; Prednisolone; Tacrolimus; Treatment Outcome | 1995 |
Phase I trial of carboplatin and infusional cyclosporin in advanced malignancy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cohort Studies; Cyclosporine; Drug Resistance; Feasibility Studies; Female; Humans; Infusions, Intravenous; Kidney Diseases; Male; Middle Aged; Neoplasms; Ovarian Neoplasms; Thrombocytopenia; Tumor Cells, Cultured | 1995 |
Amelioration of cyclosporin nephrotoxicity by Cordyceps sinensis in kidney-transplanted recipients.
Topics: Cyclosporine; Drug Therapy, Combination; Drugs, Chinese Herbal; Humans; Kidney; Kidney Diseases; Kidney Transplantation | 1995 |
Triple therapy in cadaveric renal transplantation: role of induction cyclosporine and targeted levels to avoid rejection.
Topics: Actuarial Analysis; Adolescent; Adult; Aged; Azathioprine; Cadaver; Cyclosporine; Drug Monitoring; Female; Follow-Up Studies; Graft Rejection; Graft Survival; Humans; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Prednisone | 1995 |
Cyclosporin in renal transplantation: a 9 year experience.
Topics: Adolescent; Adult; Aged; Chronic Disease; Cyclosporine; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Graft Rejection; Graft Survival; Humans; Immunosuppression Therapy; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Time Factors; Treatment Outcome | 1995 |
Preventive treatment of renal impairment and graft rejection in cardiac transplantation using cyclosporine with an oral prostaglandin analog.
Topics: Administration, Oral; Alprostadil; Biopsy, Needle; Cyclosporine; Graft Rejection; Heart Transplantation; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Prospective Studies | 1994 |
Lack of a renal-protective effect of misoprostol in rheumatoid arthritis patients receiving cyclosporin A. Results of a randomized, placebo-controlled trial.
Topics: Adult; Aged; Arthritis, Rheumatoid; Cyclosporine; Female; Gastrointestinal Diseases; Humans; Hypertension; Kidney; Kidney Diseases; Male; Middle Aged; Misoprostol; Placebos; Prospective Studies | 1994 |
Prediction of interpatient and intrapatient variation in OG 37-325 dosing requirements by the erythromycin breath test. A prospective study in renal transplant recipients.
Topics: Adult; Breath Tests; Cyclosporine; Cyclosporins; Dose-Response Relationship, Drug; Erythromycin; Female; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Patient Compliance; Predictive Value of Tests; Regression Analysis | 1994 |
Immunosuppression with low-dose cyclosporine, mizoribine, and steroids in living-related kidney transplantation.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Child; Cyclosporine; Drug Therapy, Combination; Family; Female; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Methylprednisolone; Middle Aged; Prednisolone; Ribonucleosides; Steroids; Tissue Donors | 1994 |
Misoprostol in renal transplant recipients: a prospective, randomized, controlled study on the prevention of acute rejection episodes and cyclosporin A nephrotoxicity.
Topics: Acute Disease; Administration, Oral; Cyclosporine; Female; Graft Rejection; Humans; Incidence; Kidney; Kidney Diseases; Kidney Function Tests; Kidney Transplantation; Male; Misoprostol; Prospective Studies | 1994 |
Nephrotoxicity of cyclosporine in humans: effect of cyclosporine on glomerular filtration and proximal tubular reabsorption.
Topics: Absorption; Adolescent; Adult; Aged; Cyclosporine; Female; Glomerular Filtration Rate; Hemodynamics; Humans; Kidney Diseases; Kidney Transplantation; Kidney Tubules, Proximal; Lithium; Male; Metabolic Clearance Rate; Middle Aged; Phosphates | 1993 |
Efficacy and safety of oral cyclosporin A (CyA; Sandimmun) for long-term treatment of chronic severe plaque psoriasis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Chronic Disease; Creatinine; Cyclosporine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Hypertension; Kidney Diseases; Male; Middle Aged; Neoplasms; Psoriasis; Remission Induction; Treatment Outcome | 1994 |
Reduction of cyclosporine-induced nephrotoxicity by cilastatin following clinical heart transplantation.
Topics: 6-Ketoprostaglandin F1 alpha; Acetylglucosaminidase; Adolescent; Adult; Blood Urea Nitrogen; Cilastatin; Creatinine; Cyclosporine; Female; Heart Transplantation; Hemofiltration; Humans; Kidney Diseases; Male; Middle Aged; Single-Blind Method; Thromboxane B2 | 1994 |
Chronic nephrotoxicity in psoriatic patients treated with low-dose cyclosporine.
Topics: Adult; Biopsy; Blood Pressure; Chronic Disease; Creatinine; Cyclosporine; Female; Glomerular Filtration Rate; Humans; Kidney; Kidney Diseases; Male; Middle Aged; Prospective Studies; Psoriasis; Renal Plasma Flow; Risk Factors | 1994 |
Influence of cyclosporine pharmacokinetics, trough concentrations, and AUC monitoring on outcome after kidney transplantation.
Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Cyclosporine; Drug Monitoring; Female; Follow-Up Studies; Graft Rejection; Humans; Kidney Diseases; Kidney Transplantation; Male; Metabolic Clearance Rate; Middle Aged; Racial Groups; Regression Analysis | 1993 |
Effects of the prostacyclin analogue iloprost on cyclosporin-induced renal hypoperfusion in stable renal transplant recipients.
Topics: Adult; Blood Pressure; Cyclosporine; Female; Glomerular Filtration Rate; Heart Rate; Humans; Iloprost; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Vasodilator Agents | 1996 |
Angiotensin converting enzyme inhibition and chronic cyclosporine-induced renal dysfunction in type 1 diabetes.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Creatinine; Cyclosporine; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Enalapril; Female; Glomerular Filtration Rate; Hemodynamics; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Radioimmunoassay; Renal Circulation; Sodium | 1996 |
Randomized study with cyclosporine in kidney transplantation: 10-year follow-up.
Topics: Adolescent; Adult; Azathioprine; Cataract; Child; Creatinine; Cyclosporine; Female; Follow-Up Studies; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Infections; Kidney Diseases; Kidney Transplantation; Life Tables; Male; Middle Aged; Neoplasms; Postoperative Complications; Survival Rate; Treatment Outcome | 1996 |
Mechanism of angiotensin converting enzyme inhibitor-related anemia in renal transplant recipients.
Topics: Adult; Anemia; Angiotensin-Converting Enzyme Inhibitors; Azathioprine; Cyclosporine; Drug Interactions; Enalaprilat; Erythrocytes; Erythropoietin; Female; Hematocrit; Hemoglobins; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Prospective Studies; Thioguanine | 1996 |
Pharmacokinetics of a new microemulsion formulation of cyclosporin A (Neoral) in young patients after renal transplantation.
Topics: Adolescent; Adult; Biological Availability; Child; Cyclosporine; Emulsions; Female; Glomerular Filtration Rate; Graft Rejection; Humans; Immunosuppressive Agents; Inulin; Kidney Diseases; Kidney Transplantation; Male | 1996 |
A randomized controlled trial of verapamil on cyclosporine nephrotoxicity in heart and lung transplant recipients.
Topics: Adult; Costs and Cost Analysis; Cyclosporine; Female; Glomerular Filtration Rate; Heart-Lung Transplantation; Humans; Immunosuppressive Agents; Kidney Diseases; Male; Middle Aged; Verapamil | 1997 |
Effects of pentoxifylline on renal function and blood pressure in cardiac transplant recipients: a randomized trial.
Topics: Adult; Aged; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Body Weight; Cyclosporine; Double-Blind Method; Drug Synergism; Heart Transplantation; Humans; Hypertension; Immunosuppressive Agents; Kidney; Kidney Diseases; Middle Aged; Pentoxifylline; Vasodilator Agents; Weight Gain | 1997 |
Effect of cilastatin on cyclosporine-induced acute nephrotoxicity in kidney transplant recipients.
Topics: Acute Disease; Adult; Cadaver; Cilastatin; Creatinine; Cyclosporine; Female; Graft Survival; Humans; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Prospective Studies; Protease Inhibitors | 1997 |
Tacrolimus in pancreas transplantation: a multicenter analysis. Tacrolimus Pancreas Transplant Study Group.
Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Bone Marrow Transplantation; Case-Control Studies; Cyclosporine; Diabetes Mellitus; Diabetes Mellitus, Type 1; Female; Follow-Up Studies; Gastrointestinal Diseases; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Incidence; Kidney Diseases; Kidney Transplantation; Lymphoma; Male; Muromonab-CD3; Mycophenolic Acid; Nervous System Diseases; Pancreas Transplantation; Prednisone; Prospective Studies; Randomized Controlled Trials as Topic; Survival Rate; Tacrolimus; Transplantation, Homologous | 1997 |
Acute cyclosporine toxicity after liver transplantation is predicted by the lidocaine monoethylglycinexylidide test in the donor.
Topics: Adolescent; Adult; Aged; Cyclosporine; Female; Humans; Kidney Diseases; Lidocaine; Liver Function Tests; Liver Transplantation; Male; Middle Aged; Nervous System Diseases; Prognosis; Prospective Studies; Tissue Donors | 1997 |
Renal and systemic effects of atenolol and tertatolol in renal transplant recipients on cyclosporine A.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Cross-Over Studies; Cyclosporine; Female; Glomerulonephritis; Hemodynamics; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Propanolamines; Renal Circulation; Thiophenes | 1998 |
Morphological findings in non-episode biopsies of kidney transplant allografts treated with FK506 or cyclosporine.
Topics: Biopsy; Cyclosporine; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Postoperative Complications; Tacrolimus; Vascular Diseases | 1998 |
Tacrolimus rescue therapy for cyclosporine-induced nephrotoxicity.
Topics: Cyclosporine; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Postoperative Complications; Tacrolimus | 1998 |
High-dose chemotherapy combined with escalating doses of cyclosporin A and an autologous bone marrow transplant for the treatment of drug-resistant solid tumors: a phase I clinical trial.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bacteremia; Bone Marrow Transplantation; Carboplatin; Combined Modality Therapy; Cyclophosphamide; Cyclosporine; Drug Resistance, Neoplasm; Female; Humans; Immunosuppressive Agents; Kidney Diseases; Male; Middle Aged; Mitoxantrone; Neoplasms; Transplantation, Autologous | 1995 |
Nature and mediators of renal lesions in kidney transplant patients given cyclosporine for more than one year.
Topics: Adult; Aged; Chemokine CCL2; Chemokine CCL5; Cyclosporine; Endothelin-1; Female; Humans; Immunosuppressive Agents; Incidence; Kidney; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; RNA, Messenger | 1999 |
Red blood cell rigidification during cyclosporin therapy: a possible early warning signal for adverse reactions.
Topics: Cyclosporine; Erythrocyte Aggregation; Erythrocyte Deformability; Hematology; Humans; Immunosuppressive Agents; Kidney Diseases; Postoperative Complications; Predictive Value of Tests; Prospective Studies; Psoriasis | 1998 |
Renal hemodynamic effects of L-arginine and sodium nitroprusside in heart transplant recipients.
Topics: Aged; Arginine; Blood Pressure; Chronic Disease; Cohort Studies; Cyclosporine; Glomerular Filtration Rate; Heart Transplantation; Humans; Immunosuppressive Agents; Injections, Intravenous; Kidney; Kidney Diseases; Male; Middle Aged; Nitric Oxide; Nitroprusside; Renal Circulation; Vasodilator Agents | 1999 |
Differential effects of cyclosporin and tacrolimus on the expression of fibrosis-associated genes in isolated glomeruli from renal transplants.
Topics: Adult; Collagen; Cyclosporine; Female; Fibrosis; Gene Expression; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Glomerulus; Kidney Transplantation; Male; Matrix Metalloproteinase 2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tacrolimus; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Transforming Growth Factor beta | 2000 |
Replacement of calcineurin inhibitors with mycophenolate mofetil in liver-transplant patients with renal dysfunction: a randomised controlled study.
Topics: Blood Pressure; Calcineurin Inhibitors; Cholesterol; Creatinine; Cyclosporine; Female; Humans; Immunosuppressive Agents; Kidney Diseases; Liver Transplantation; Male; Middle Aged; Mycophenolic Acid; Tacrolimus | 2001 |
Molecular and structural consequences of early renal allograft injury.
Topics: Adult; Cyclosporine; Female; Fibronectins; Fibrosis; Gene Expression; Graft Rejection; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Prospective Studies; RNA, Messenger; Tacrolimus; Thrombospondins; Transforming Growth Factor beta; Transforming Growth Factor beta1; Transplantation, Homologous | 2002 |
Long term efficacy and safety of cyclosporin versus parenteral gold in early rheumatoid arthritis: a three year study of radiographic progression, renal function, and arterial hypertension.
Topics: Activities of Daily Living; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Creatinine; Cyclosporine; Disabled Persons; Female; Gold Sodium Thiomalate; Humans; Hypertension; Injections; Kidney Diseases; Long-Term Care; Male; Middle Aged; Treatment Outcome | 2002 |
A trial of the prostaglandin E1 analogue, enisoprost, to reverse chronic cyclosporine-associated renal dysfunction.
Topics: Adult; Alprostadil; Blood Pressure; Cyclosporine; Double-Blind Method; Drug Evaluation; Female; Glomerular Filtration Rate; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Renal Circulation; Vascular Resistance | 1992 |
A prospective, randomized, double-blind study of trimethoprim-sulfamethoxazole for prophylaxis of infection in renal transplantation. Side effects of trimethoprim-sulfamethoxazole, interaction with cyclosporine.
Topics: Creatinine; Cyclosporine; Double-Blind Method; Drug Interactions; Humans; Infections; Kidney Diseases; Kidney Transplantation; Patient Compliance; Postoperative Complications; Prospective Studies; Trimethoprim, Sulfamethoxazole Drug Combination | 1992 |
Double-blind comparison of teicoplanin versus vancomycin in febrile neutropenic patients receiving concomitant tobramycin and piperacillin: effect on cyclosporin A-associated nephrotoxicity.
Topics: Adult; Aged; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Creatinine; Cyclosporine; Double-Blind Method; Drug Interactions; Female; Fever; Glycopeptides; Humans; Kidney Diseases; Male; Middle Aged; Neutropenia; Piperacillin; Teicoplanin; Tobramycin; Vancomycin | 1991 |
623 other study(ies) available for cyclosporine and Kidney Diseases
| Article | Year |
|---|---|
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Protective effect of dapagliflozin against cyclosporine A-induced nephrotoxicity.
Topics: Animals; Antioxidants; bcl-2-Associated X Protein; Caspase 3; Cyclosporine; Immunosuppressive Agents; Kidney; Kidney Diseases; Malondialdehyde; Mice; Oxidants; Peroxidase | 2022 |
Geraniol protects against cyclosporine A-induced renal injury in rats: Role of Wnt/β-catenin and PPARγ signaling pathways.
Topics: Acute Kidney Injury; Acyclic Monoterpenes; Animals; Apoptosis; beta Catenin; Cyclosporine; Inflammation; Kidney; Kidney Diseases; Male; NF-kappa B; PPAR gamma; Rats; Rats, Wistar; Wnt Signaling Pathway | 2022 |
NEPHROPROTECTIVE EFFECTS OF CURCUMIN AGAINST CYCLOSPORINE A-INDUCED NEPHROTOXICITY IN RAT MODEL.
Topics: Animals; Curcumin; Cyclosporine; Kidney Diseases; Rats; Rats, Wistar; Renal Insufficiency | 2021 |
Severe infections and renal dysfunction during immunosuppressive therapy with cyclosporine A for aplastic anemia.
Topics: Aged; Anemia, Aplastic; Antilymphocyte Serum; Creatinine; Cyclosporine; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Kidney Diseases; Retrospective Studies; Treatment Outcome | 2022 |
TAFRO syndrome with renal biopsy successfully treated with steroids and cyclosporine: a case report.
Topics: Biopsy; Castleman Disease; Cyclosporine; Edema; Female; Humans; Kidney Diseases; Middle Aged; Steroids; Thrombotic Microangiopathies; Vascular Endothelial Growth Factor A | 2022 |
Early Postoperative Kidney Transplant Complications Related to Immunomodulator Regimen in Pediatric Recipients.
Topics: Adolescent; Child; Child, Preschool; Cyclosporine; Female; Graft Rejection; Graft Survival; Humans; Immunologic Factors; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Prospective Studies; Tacrolimus; Transplant Recipients; Treatment Outcome; Viremia | 2022 |
Basiliximab for the therapy of acute T cell-mediated rejection in kidney transplant recipient with BK virus infection: A case report.
Topics: Aged; Basiliximab; BK Virus; Creatinine; Cyclosporine; Graft Rejection; Humans; Kidney Diseases; Kidney Transplantation; Male; Mycophenolic Acid; Polyomavirus Infections; Prednisolone; Prednisone; T-Lymphocytes | 2022 |
[Efficacy of rituximab in minimal change disease, an atypical renal manifestation of antiphospholipid syndrome].
Topics: Adult; Antibodies, Antiphospholipid; Antibodies, Monoclonal; Anticoagulants; Antiphospholipid Syndrome; Cyclophosphamide; Cyclosporine; Humans; Infant; Kidney; Kidney Diseases; Nephrosis, Lipoid; Nephrotic Syndrome; Prednisone; Rituximab; Young Adult | 2022 |
Effects of diurnal variation of bile acids by meal on cyclosporine A absorption.
Topics: Bile Acids and Salts; Child; Cyclosporine; Humans; Immunosuppressive Agents; Kidney Diseases; Meals; Retrospective Studies | 2022 |
Amelioration of Cyclosporine A-Induced Acute Nephrotoxicity by
Topics: Animals; Cyclosporine; Endoplasmic Reticulum Chaperone BiP; Immunosuppressive Agents; Kidney; Kidney Diseases; Magnesium; Male; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley | 2023 |
Nephroprotective effects of Candesartan Cilexetil against Cyclosporine A-induced nephrotoxicity in a rat model.
Topics: Animals; Catalase; Creatinine; Cyclosporine; Immunosuppressive Agents; Interleukin-2; Kidney; Kidney Diseases; Oxidative Stress; Rats; Rats, Wistar; Renal Insufficiency; Superoxide Dismutase; Urea | 2022 |
Preclinical Study of DNA-Recognized Peptide Compound Pyrrole-Imidazole Polyamide Targeting Human TGF-β1 Promoter for Progressive Renal Diseases in the Common Marmoset.
Topics: Animals; Base Sequence; Cadherins; Callithrix; Cyclosporine; DNA; Fibrosis; Humans; Imidazoles; Kidney; Kidney Diseases; Nylons; Peptides; Promoter Regions, Genetic; Pyrroles; RNA, Messenger; Snail Family Transcription Factors; Transforming Growth Factor beta1; Urethral Obstruction | 2019 |
Urotensin receptor antagonist palosuran attenuates cyclosporine-a-induced nephrotoxicity in rats.
Topics: Animals; Creatinine; Cyclosporine; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Models, Animal; Quinolines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Urea; Urotensins | 2019 |
The Effect of Cyclosporine and the Consequences in Hepatic and Renal Function Following Ischemic Stroke in a Rats' Model.
Topics: Animals; Anti-Inflammatory Agents; Biomarkers; Brain Ischemia; Cyclosporine; Disease Models, Animal; Kidney; Kidney Diseases; Liver; Liver Diseases; Male; Rats, Wistar; Stroke; Time Factors | 2020 |
Delineating a role for the mitochondrial permeability transition pore in diabetic kidney disease by targeting cyclophilin D.
Topics: Albuminuria; Animals; Cyclosporine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Hydrogen Peroxide; Kidney; Kidney Diseases; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Peptidyl-Prolyl Isomerase F; Proton-Translocating ATPases | 2020 |
The role of candidate genetic polymorphisms in the interaction between voriconazole and cyclosporine in patients undergoing allogeneic hematopoietic cell transplantation: An explorative study.
Topics: Adult; Aged; Allografts; Antifungal Agents; ATP Binding Cassette Transporter, Subfamily B; Biotransformation; Carrier Proteins; Cyclosporine; Cyclosporins; Cytochromes; Dose-Response Relationship, Drug; Drug Interactions; Female; Genetic Association Studies; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Kidney Diseases; Male; Middle Aged; Pharmacogenomic Testing; Pilot Projects; Transplantation Conditioning; Voriconazole; Young Adult | 2020 |
Dehydroxymethylepoxyquinomicin, a novel nuclear factor-κB inhibitor, prevents the development of cyclosporine A nephrotoxicity in a rat model.
Topics: Animals; Benzamides; Cyclohexanones; Cyclosporine; DNA; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; NF-kappa B; Protective Agents; Rats, Sprague-Dawley | 2020 |
Metformin and silymarin afford protection in cyclosporine A induced hepatorenal toxicity in rat by modulating redox status and inflammation.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cyclosporine; Inflammation; Kidney Diseases; Male; Metformin; Oxidation-Reduction; Rats; Rats, Wistar; Silymarin | 2021 |
Cyclosporine A induces kidney dysfunction by the alteration of molecular mediators involved in slit diaphragm regulation and matrix metalloproteins: the mitigating effect of curcumin.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Curcumin; Cyclosporine; Gene Expression Regulation; Glomerular Filtration Rate; Immunosuppressive Agents; Kidney Diseases; Male; Metalloproteins; Podocytes; Rats; Rats, Wistar | 2020 |
Proteomic Characterization of Urinary Extracellular Vesicles from Kidney-Transplanted Patients Treated with Calcineurin Inhibitors.
Topics: Adult; Aged; Biomarkers; Calcineurin Inhibitors; Cyclosporine; Extracellular Vesicles; Female; Fibrosis; Graft Survival; Humans; Kidney; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Plakins; Proteome; Tacrolimus; Uroplakins | 2020 |
The Pattern of Cyclosporine Nephrotoxicity and Urinary Kidney Injury Molecule 1 in Allogenic Hematopoietic Stem Cell Transplant Patients.
Topics: Adolescent; Creatinine; Cyclosporine; Female; Hematopoietic Stem Cell Transplantation; Humans; Kidney; Kidney Diseases; Male; Treatment Outcome | 2021 |
Calcineurin A-α suppression drives nuclear factor-κB-mediated NADPH oxidase-2 upregulation.
Topics: Animals; Calcineurin; Calcineurin Inhibitors; Cell Line; Cyclosporine; Fibrosis; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidase 2; NF-kappa B; Oxidative Stress; Reactive Oxygen Species; Up-Regulation | 2021 |
Sodium-glucose cotransporter 2 inhibition prevents renal fibrosis in cyclosporine nephropathy.
Topics: Animals; Benzhydryl Compounds; Blood Pressure; Cyclosporine; Fibrosis; Glucosides; Kidney; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2021 |
Lysyl oxidase inhibitors attenuate cyclosporin A-induced nephropathy in mouse.
Topics: Amino Acid Oxidoreductases; Animals; Cyclosporine; Disease Models, Animal; Extracellular Matrix; Extracellular Matrix Proteins; Fibrosis; Humans; Kidney Diseases; Kidney Tubules; Male; Mice; Protective Agents; Protein-Lysine 6-Oxidase | 2021 |
Effects of calcineurin inhibitors on sodium excretion in recipients of allogeneic hematopoietic stem cell transplantation.
Topics: Adolescent; Adult; Aged; Allografts; Calcineurin Inhibitors; Cyclosporine; Female; Hematopoietic Stem Cell Transplantation; Humans; Kidney Diseases; Male; Middle Aged; Retrospective Studies; Sodium; Tacrolimus; Young Adult | 2017 |
A delicate balance between rejection and BK polyomavirus associated nephropathy; A retrospective cohort study in renal transplant recipients.
Topics: Adult; BK Virus; Cyclosporine; Female; Genotype; Graft Rejection; Host-Pathogen Interactions; Humans; Immunosuppressive Agents; Kaplan-Meier Estimate; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Multivariate Analysis; Mycophenolic Acid; Outcome Assessment, Health Care; Polyomavirus Infections; Retrospective Studies; Tacrolimus; Transplant Recipients; Tumor Virus Infections | 2017 |
Ten-Year Follow-up of Pharmacokinetics-Guided Very Early Cyclosporine Minimization Synchronized With Everolimus Initiation in De Novo Kidney Transplantation.
Topics: Adult; Aged; Cyclosporine; Drug Therapy, Combination; Everolimus; Female; Follow-Up Studies; Glomerular Filtration Rate; Graft Survival; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Function Tests; Kidney Transplantation; Male; Middle Aged; Regression Analysis; Time Factors | 2017 |
miR-181c protects CsA-induced renal damage and fibrosis through inhibiting EMT.
Topics: Animals; Cell Line, Transformed; Cyclosporine; Epithelial-Mesenchymal Transition; Humans; Kidney; Kidney Diseases; Mice; Mice, Knockout; MicroRNAs; NF-E2-Related Factor 2; Receptor, Notch2 | 2017 |
Cyclosporine A exhibits gender-specific nephrotoxicity in rats: Effect on renal tissue inflammation.
Topics: Animals; Creatine; Cyclosporine; Female; Immunosuppressive Agents; Inflammation; Kidney; Kidney Diseases; Male; Rats; Rats, Wistar; Sex Characteristics; Sex Factors | 2018 |
Calcineurin inhibitor-induced complement system activation via ERK1/2 signalling is inhibited by SOCS-3 in human renal tubule cells.
Topics: Aged; Aged, 80 and over; Apoptosis; Calcineurin Inhibitors; CD55 Antigens; Cell Line; Cell Survival; Complement Membrane Attack Complex; Complement System Proteins; Cyclosporine; Drug-Related Side Effects and Adverse Reactions; Female; Gene Expression Regulation; Graft Rejection; Humans; Kidney Diseases; Kidney Transplantation; Kidney Tubules; Male; MAP Kinase Signaling System; Membrane Cofactor Protein; Middle Aged; Phosphorylation; RNA, Small Interfering; Suppressor of Cytokine Signaling 3 Protein; Tacrolimus | 2018 |
Adverse Events under Tacrolimus and Cyclosporine in the First 3 Years Post-Renal Transplantation in Children.
Topics: Adolescent; Child; Child, Preschool; Cyclosporine; Female; Follow-Up Studies; Gastrointestinal Diseases; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Neutropenia; Retrospective Studies; Tacrolimus; Time Factors; Young Adult | 2018 |
D‑Pinitol alleviates cyclosporine A‑induced renal tubulointerstitial fibrosis via activating Sirt1 and Nrf2 antioxidant pathways.
Topics: Animals; Antioxidants; Cyclosporine; Fibrosis; Inositol; Kidney; Kidney Diseases; Kidney Function Tests; Male; Mice, Inbred ICR; NF-E2-Related Factor 2; Oxidative Stress; Sirtuin 1 | 2018 |
Protective effect of curcumin against cyclosporine A‑induced rat nephrotoxicity.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cell Line; Curcumin; Cyclosporine; Disease Models, Animal; Humans; Kidney; Kidney Diseases; Kidney Function Tests; Male; Oxidative Stress; Protective Agents; Proto-Oncogene Proteins c-bcl-2; Rats; Reactive Oxygen Species | 2018 |
Enhanced lipoxygenase/LTD4 signaling accounts for the exaggerated hypertensive and nephrotoxic effects of cyclosporine plus indomethacin in rats.
Topics: Animals; Blood Pressure; Cyclosporine; Drug Interactions; Hypertension; Indomethacin; Kidney; Kidney Diseases; Leukotriene D4; Lipoxygenase; Male; Rats, Sprague-Dawley; Signal Transduction | 2018 |
Molecular basis of the counteraction by calcium channel blockers of cyclosporine nephrotoxicity.
Topics: Animals; Biomarkers; Blood Urea Nitrogen; Calcium Channel Blockers; Collagen Type IV; Creatinine; Cyclosporine; Dual Oxidases; Fibrosis; Inflammation Mediators; Kidney; Kidney Diseases; Male; NADPH Oxidases; NF-kappa B; Nifedipine; Oxidative Stress; Proteinuria; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Transforming Growth Factor beta1; Verapamil | 2018 |
Nephrotoxicity and Kidney Transport Assessment on 3D Perfused Proximal Tubules.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Culture Techniques; Cell Line; Cell Polarity; Cisplatin; Cyclosporine; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Kidney Diseases; Kidney Tubules, Proximal; Lab-On-A-Chip Devices; Membrane Transport Modulators; Membrane Transport Proteins; Microfluidic Analytical Techniques; Perfusion; Phlorhizin; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Tight Junctions | 2018 |
Repaglinide inhibits cyclosporine A-induced renal tubular toxicity\
by affecting apoptosis and \
Bax\
and \
Bcl-2\
expression
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Carbamates; Cyclosporine; Hypoglycemic Agents; Kidney; Kidney Diseases; Kidney Tubules; Male; Piperidines; Proto-Oncogene Proteins c-bcl-2; Rats, Sprague-Dawley | 2018 |
Once-Daily Low-Dose Cyclosporine A Treatment with Angiotensin Blockade for Long-Term Remission of Nephropathy in Frasier Syndrome.
Topics: Adolescent; Angiotensin Receptor Antagonists; Biopsy; Child; Child, Preschool; Creatinine; Cyclosporine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Frasier Syndrome; Humans; Kidney; Kidney Diseases; Proteinuria | 2019 |
The therapeutic effect of switching from tacrolimus to low-dose cyclosporine A in renal transplant recipients with BK virus nephropathy.
Topics: Adult; BK Virus; Cyclosporine; Female; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Polyomavirus Infections; Tacrolimus | 2019 |
Risk factors for increased serum creatinine level in patients with psoriasis treated with cyclosporine in a real-world practice.
Topics: Adult; Age Factors; Aged; Creatinine; Cyclosporine; Diabetes Mellitus; Female; Humans; Immunosuppressive Agents; Kidney Diseases; Male; Middle Aged; Obesity; Psoriasis; Retrospective Studies; Risk Factors | 2019 |
Modulation of eNOS/iNOS by nebivolol protects against cyclosporine A-mediated nephrotoxicity through targeting inflammatory and apoptotic pathways.
Topics: Adrenergic beta-1 Receptor Antagonists; Animals; Anti-Inflammatory Agents; Apoptosis; Cyclosporine; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Nebivolol; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Protective Agents; Rats, Wistar | 2019 |
Omega-3 fatty acid decreases oleic acid by decreasing SCD-1 expression in the liver and kidney of a cyclosporine-induced nephropathy rat model.
Topics: Acetyltransferases; Animals; Cell Membrane; Cyclosporine; Dietary Supplements; Disease Models, Animal; Erythrocytes; Fatty Acid Elongases; Fatty Acids, Omega-3; Kidney; Kidney Diseases; Lipid Metabolism; Liver; Male; Oleic Acid; Rats; Rats, Sprague-Dawley; Stearoyl-CoA Desaturase | 2019 |
Tauroursodeoxycholic acid attenuates cyclosporine-induced renal fibrogenesis in the mouse model.
Topics: Animals; Cyclosporine; Disease Models, Animal; Fibrosis; Kidney; Kidney Diseases; Male; Mice; Taurochenodeoxycholic Acid; Unfolded Protein Response | 2019 |
Collaborative Brazilian pediatric renal transplant registry (CoBrazPed-RTx): A report from 2004 to 2018.
Topics: Adolescent; Brazil; Child; Cyclosporine; Female; Follow-Up Studies; Graft Rejection; Graft Survival; Humans; International Cooperation; Kidney Diseases; Kidney Failure, Chronic; Kidney Transplantation; Living Donors; Male; Postoperative Complications; Registries; Thrombosis; Tissue and Organ Procurement | 2019 |
The role of protein kinase CK2 in cyclosporine-induced nephropathy in rats.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Casein Kinase II; Caspase 3; Caspase 7; Caspase 8; Cyclosporine; Diet, Sodium-Restricted; Disease Models, Animal; Emodin; Immunohistochemistry; Kidney; Kidney Diseases; Male; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Tumor Suppressor Protein p53 | 2013 |
Sildenafil protects against nitric oxide deficiency-related nephrotoxicity in cyclosporine A treated rats.
Topics: Albuminuria; Animals; Catalase; Creatinine; Cyclosporine; Glutathione; Immunosuppressive Agents; Kidney Diseases; Male; Malondialdehyde; Nitrates; Nitric Oxide; Nitrites; Phosphodiesterase 5 Inhibitors; Piperazines; Protective Agents; Purines; Rats; Rats, Wistar; Sildenafil Citrate; Sulfones; Urea | 2013 |
Ginseng treatment attenuates chronic cyclosporine nephropathy via reducing oxidative stress in an experimental mouse model.
Topics: Animals; Biomarkers; Cell Line; Cyclosporine; Herb-Drug Interactions; Humans; Immunosuppressive Agents; Kidney Diseases; Male; Mice; Oxidative Stress; Panax; Phytotherapy; Plant Extracts; Random Allocation | 2013 |
Serum and renal tissue markers of nephropathy in rats under immunosuppressive therapy: cyclosporine versus sirolimus.
Topics: Animals; Biomarkers; Blood Pressure; Cyclosporine; Heart Rate; Immunosuppressive Agents; Kidney Diseases; Male; Rats; Rats, Wistar; Sirolimus | 2013 |
Successful use of mycophenolate mofetil to treat severe chronic urticaria in a patient intolerant to ciclosporin.
Topics: Adult; Chronic Disease; Cyclosporine; Female; Humans; Immunosuppressive Agents; Kidney Diseases; Mycophenolic Acid; Treatment Outcome; Urticaria | 2014 |
Green tea polyphenols stimulate mitochondrial biogenesis and improve renal function after chronic cyclosporin a treatment in rats.
Topics: Animals; Cyclosporine; Diet; DNA-Binding Proteins; DNA, Mitochondrial; Electron Transport Complex I; Gene Dosage; Kidney; Kidney Diseases; Kidney Function Tests; Male; Mitochondria; Mitochondrial Proteins; Mitochondrial Proton-Translocating ATPases; Mitochondrial Turnover; Oxidative Phosphorylation; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Polyphenols; Rats, Sprague-Dawley; RNA, Messenger; Tea; Transcription Factors | 2014 |
Prediction of clinically relevant safety signals of nephrotoxicity through plasma metabolite profiling.
Topics: Animals; Captopril; Cyclosporine; Doxorubicin; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Kidney Diseases; Lisinopril; Male; Metabolome; Metabolomics; Phenytoin; Rats; Rats, Wistar | 2013 |
Influence of N-acetylcysteine on Klotho expression and its signaling pathway in experimental model of chronic cyclosporine nephropathy in mice.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Antioxidants; Apoptosis; Chronic Disease; Cyclosporine; Deoxyguanosine; Disease Models, Animal; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression; Glucuronidase; Immunosuppressive Agents; Kidney Diseases; Klotho Proteins; Male; Mice; Mice, Inbred ICR; Oxidative Stress; Proto-Oncogene Proteins c-akt; Signal Transduction; Superoxide Dismutase | 2013 |
Novel self-emulsifying formulation of quercetin for improved in vivo antioxidant potential: implications for drug-induced cardiotoxicity and nephrotoxicity.
Topics: Animals; Antineoplastic Agents; Antioxidants; Biological Availability; Caco-2 Cells; Cardiotoxicity; Chemistry, Pharmaceutical; Cyclosporine; Doxorubicin; Drug Delivery Systems; Emulsifying Agents; Emulsions; Female; Humans; Kidney Diseases; Microscopy, Confocal; Quercetin; Rats; Rats, Sprague-Dawley | 2013 |
Cyclosporin A may cause injury to undifferentiated glomeruli persisting in patients with Alport syndrome.
Topics: Adolescent; Biopsy; Cell Differentiation; Child; Collagen Type IV; Cyclosporine; Female; Follow-Up Studies; Humans; Kidney Diseases; Kidney Glomerulus; Laminin; Male; Nephritis, Hereditary; Retrospective Studies; Risk Factors; Young Adult | 2014 |
Comment on "Carbamylated erythropoietin ameliorates cyclosporine nephropathy without stimulating erythropoiesis".
Topics: Animals; Cyclosporine; Erythropoietin; Humans; Immunosuppressive Agents; Kidney Diseases; Male | 2014 |
Synergistic protective effects of mizoribine and angiotensin II receptor blockade on cyclosporine A nephropathy in rats.
Topics: Angiotensin Receptor Antagonists; Animals; Body Weight; Cyclosporine; Drug Synergism; Immunosuppressive Agents; Kidney Diseases; Male; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Ribonucleosides | 2014 |
Association of BK viremia with human leukocyte antigen mismatches and acute rejection, but not with type of calcineurin inhibitor.
Topics: Adult; Aged; Allografts; Antibodies, Monoclonal; Azathioprine; Basiliximab; BK Virus; Cohort Studies; Cyclosporine; Female; Glomerular Filtration Rate; Graft Rejection; Histocompatibility; HLA Antigens; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Logistic Models; Male; Middle Aged; Multivariate Analysis; Mycophenolic Acid; Polyomavirus Infections; Proteinuria; Pyrroles; Quinazolines; Recombinant Fusion Proteins; Tacrolimus; Tumor Virus Infections; Viremia | 2014 |
Calcineurin inhibitors: 40 years later, can't live without ...
Topics: Animals; Autoimmune Diseases; Calcineurin; Calcineurin Inhibitors; Clinical Trials as Topic; Cyclosporine; Diabetes Mellitus, Type 2; Drug Evaluation, Preclinical; Drug Therapy, Combination; Forecasting; Graft Rejection; History, 20th Century; History, 21st Century; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Lymphocyte Activation; Meta-Analysis as Topic; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; T-Lymphocytes; Tacrolimus | 2013 |
Therapeutic efficacy of naringin on cyclosporine (A) induced nephrotoxicity in rats: involvement of hemeoxygenase-1.
Topics: Animals; Antioxidants; Ascorbic Acid; Catalase; Cyclosporine; Cytoprotection; Disease Models, Animal; Flavanones; Heme Oxygenase (Decyclizing); Hydroxyl Radical; Kidney; Kidney Diseases; Male; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Time Factors; Vitamin A; Vitamin E | 2013 |
Cyclosporine nephrotoxicity and early posttransplant hyperkalemia in living-donor renal recipients: report of 4 cases.
Topics: Adult; Aged; Calcineurin Inhibitors; Cyclosporine; Drug Monitoring; Fludrocortisone; Humans; Hyperkalemia; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Living Donors; Male; Predictive Value of Tests; Pseudohypoaldosteronism; Risk Factors; Severity of Illness Index; Time Factors; Transplant Recipients; Treatment Outcome | 2014 |
Celecoxib offsets the negative renal influences of cyclosporine via modulation of the TGF-β1/IL-2/COX-2/endothelin ET(B) receptor cascade.
Topics: Animals; Celecoxib; Creatinine; Cyclooxygenase 2; Cyclosporine; Fibrosis; Immunosuppressive Agents; Interleukin-2; Kidney; Kidney Diseases; Male; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Signal Transduction; Sulfonamides; Transforming Growth Factor beta1 | 2014 |
Bortezomib-based antibody-mediated rejection therapy and simultaneous conversion to belatacept.
Topics: Abatacept; Adult; Azathioprine; Biopsy; Boronic Acids; Bortezomib; Calcineurin Inhibitors; Cyclosporine; Glomerulonephritis, IGA; Graft Rejection; Humans; Immunoconjugates; Immunosuppression Therapy; Immunosuppressive Agents; Kidney Diseases; Kidney Failure, Chronic; Kidney Transplantation; Male; Prednisone; Pyrazines; Treatment Outcome | 2014 |
Delayed treatment with oleanolic acid attenuates tubulointerstitial fibrosis in chronic cyclosporine nephropathy through Nrf2/HO-1 signaling.
Topics: Adaptor Proteins, Signal Transducing; Animals; Antioxidants; Apoptosis; Biomarkers; Cell Nucleus; Cyclosporine; Cytoskeletal Proteins; Fibrosis; Heme Oxygenase-1; Kelch-Like ECH-Associated Protein 1; Kidney Diseases; Kidney Function Tests; Kidney Tubules; Male; Malondialdehyde; Mice; Mice, Inbred ICR; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Oleanolic Acid; Proto-Oncogene Proteins c-bcl-2; Signal Transduction | 2014 |
Evidence for a gene controlling the induction of transplantation tolerance.
Topics: Animals; Combined Modality Therapy; Cyclosporine; Graft Rejection; Histocompatibility Antigens Class I; Histocompatibility Antigens Class II; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Swine; Swine, Miniature; Transplantation Tolerance | 2014 |
Mycelia glycoproteins from Cordyceps sobolifera ameliorate cyclosporine-induced renal tubule dysfunction in rats.
Topics: Animals; Apoptosis; Cordyceps; Cyclosporine; Immunosuppressive Agents; Kidney; Kidney Diseases; Mycelium; Polysaccharides; Rats, Sprague-Dawley; TRPM Cation Channels | 2014 |
Once-daily oral administration of cyclosporine in a lung transplant patient with a history of renal toxicity of calcineurin inhibitors.
Topics: Administration, Oral; Adolescent; Calcineurin Inhibitors; Cyclosporine; Drug Administration Schedule; Drug Monitoring; Graft Rejection; Graft Survival; Humans; Kidney Diseases; Lung Transplantation; Male; Respiratory Insufficiency; Tacrolimus; Time Factors; Treatment Outcome | 2014 |
Ginseng treatment attenuates autophagic cell death in chronic cyclosporine nephropathy.
Topics: Animals; Autophagy; Chronic Disease; Cyclosporine; Kidney Diseases; Male; Mice; Mice, Inbred ICR; Panax; Phytotherapy; Plant Extracts | 2014 |
Transition from cyclosporine-induced renal dysfunction to nephrotoxicity in an in vivo rat model.
Topics: Animals; Biomarkers; Blood Urea Nitrogen; Creatinine; Cyclosporine; Cytokines; Disease Models, Animal; Immunosuppressive Agents; Inflammation Mediators; Kidney; Kidney Diseases; Male; Rats; Rats, Wistar; RNA, Messenger; TOR Serine-Threonine Kinases; Up-Regulation | 2014 |
Conversion to sirolimus ameliorates cyclosporine-induced nephropathy in the rat: focus on serum, urine, gene, and protein renal expression biomarkers.
Topics: Animals; Biomarkers; Cell Proliferation; Collagen; Cyclosporine; Gene Expression Regulation; Immunohistochemistry; Inflammation; Kidney; Kidney Diseases; Male; Neovascularization, Physiologic; Proteins; Rats, Wistar; RNA, Messenger; Sirolimus | 2014 |
Altered expression of alpha 2 beta 1 integrin in kidney fibroblasts: a potential mechanism for CsA-induced nephrotoxicity.
Topics: Animals; Antioxidants; Cell Adhesion; Cyclosporine; Fibroblasts; Gene Expression; Immunosuppressive Agents; Integrin alpha2beta1; Kidney; Kidney Diseases; Male; Quercetin; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vitamin E | 2014 |
Predictive usefulness of urinary biomarkers for the identification of cyclosporine A-induced nephrotoxicity in a rat model.
Topics: Animals; Biomarkers; Cell Adhesion Molecules; Cyclosporine; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Fibronectins; Glomerular Filtration Rate; Immunohistochemistry; Immunosuppressive Agents; Interleukin-6; Kidney; Kidney Diseases; Osteopontin; Rats; Rats, Wistar; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Vimentin | 2014 |
Clinical relevance of post-transplant pharmacodynamic analysis of cyclosporine in renal transplantation.
Topics: Adult; Antibodies; Cyclosporine; Cytomegalovirus; Female; Graft Rejection; Herpesvirus 3, Human; HLA Antigens; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; T-Lymphocytes; Virus Activation | 2014 |
Protective effects of 2-deoxy-D-glucose on nephrotoxicity induced by cyclosporine A in rats.
Topics: Animals; Antimetabolites; Blotting, Western; Cyclosporine; Deoxyglucose; Immunohistochemistry; Immunosuppressive Agents; Kidney; Kidney Diseases; Rats; Rats, Sprague-Dawley | 2014 |
Consensus on the use of cyclosporine in dermatological practice. Italian Consensus Conference.
Topics: Adult; Child; Cyclosporine; Dermatitis, Atopic; Disease Susceptibility; Drug Administration Schedule; Drug Interactions; Female; Food-Drug Interactions; Humans; Hypertension; Immunosuppressive Agents; Infections; Kidney Diseases; Neoplasms; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications; Psoriasis; Quality of Life; Skin Diseases | 2014 |
Cytomegalovirus disease in patients with glomerular diseases treated by immunosuppressive treatment.
Topics: Adult; Azathioprine; Biopsy; Cyclophosphamide; Cyclosporine; Cytomegalovirus Infections; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Kidney Diseases; Male; Middle Aged; Mycophenolic Acid; Real-Time Polymerase Chain Reaction; Retrospective Studies; Risk Factors; Turkey | 2014 |
Phosphodiesterase type 5 inhibition attenuates cyclosporine A induced nephrotoxicity in mice.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Body Weight; Cyclosporine; Glyceraldehyde-3-Phosphate Dehydrogenases; Immunohistochemistry; Immunosuppressive Agents; Kidney Diseases; Male; Mice; Organ Size; Oxidative Stress; Phosphodiesterase 5 Inhibitors; Platelet-Derived Growth Factor; Prostaglandin-Endoperoxide Synthases; Transforming Growth Factor beta1; Vardenafil Dihydrochloride | 2015 |
Inhibition of local aldosterone by eplerenone reduces renal structural damage in a novel model of chronic cyclosporine A nephrotoxicity.
Topics: Adrenalectomy; Aldosterone; Animals; Chronic Disease; Cyclosporine; Cytochrome P-450 CYP11B2; Disease Models, Animal; Electrolytes; Eplerenone; Fibrosis; Kidney; Kidney Diseases; Male; Potassium; Rats, Sprague-Dawley; RNA, Messenger; Sodium; Spironolactone | 2015 |
The role of peroxisome-proliferator-activating receptor gamma agonists: rosiglitazone and 15-deoxy-delta12,14-prostaglandin J2 in chronic experimental cyclosporine A-induced nephrotoxicity.
Topics: Animals; Creatinine; Cyclosporine; Disease Models, Animal; Glutathione; Glutathione Disulfide; Kidney; Kidney Diseases; Male; NAD; NADP; PPAR gamma; Prostaglandin D2; Protective Agents; Rats, Wistar; Rosiglitazone; Thiazolidinediones; Urea; Uric Acid | 2014 |
Protective role of cyclosporine A and minocycline on mitochondrial disequilibrium-related podocyte injury and proteinuria occurrence induced by adriamycin.
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Apoptosis; Caspase 3; Cyclosporine; Doxorubicin; Fluorescent Antibody Technique; Immunosuppressive Agents; Kidney Diseases; Male; Membrane Potential, Mitochondrial; Minocycline; Mitochondria; Podocytes; Proteinuria; Rats; Rats, Sprague-Dawley | 2015 |
The Protective Effect of Apocynin on Cyclosporine A-Induced Hypertension and Nephrotoxicity in Rats.
Topics: Acetophenones; Animals; Blood Pressure; Cyclosporine; Enzyme Inhibitors; Glomerular Filtration Rate; Hypertension; Kidney Diseases; Male; NADPH Oxidases; Nitric Oxide; Rats; Rats, Sprague-Dawley | 2015 |
Cyclosporine A-induced nephrotoxicity is ameliorated by dose reduction and conversion to sirolimus in the rat.
Topics: Acute-Phase Proteins; Animals; Biomarkers; Blood Glucose; Blood Pressure; Cell Adhesion Molecules; Cholesterol; Connective Tissue Growth Factor; Creatinine; Cyclosporine; Glomerular Filtration Rate; Heart Rate; Kidney; Kidney Diseases; Lipid Peroxidation; Lipocalin-2; Lipocalins; Male; NF-kappa B; Proto-Oncogene Proteins; Rats; Rats, Wistar; Sirolimus; TOR Serine-Threonine Kinases; Triglycerides; Urea | 2015 |
Amelioration of cyclosporine induced nephrotoxicity by dipeptidyl peptidase inhibitor vildagliptin.
Topics: Adamantane; Animals; bcl-2-Associated X Protein; Blood Urea Nitrogen; Creatinine; Cyclosporine; Dipeptidyl-Peptidase IV Inhibitors; Glutathione; Immunosuppressive Agents; Kidney; Kidney Diseases; L-Lactate Dehydrogenase; Lipid Peroxidation; Male; Nitriles; Protective Agents; Proto-Oncogene Proteins c-bcl-2; Pyrrolidines; Rats, Wistar; Serum Albumin; Superoxide Dismutase; Vildagliptin | 2015 |
Pharmacokinetic and nephroprotective benefits of using Schisandra chinensis extracts in a cyclosporine A-based immune-suppressive regime.
Topics: Animals; Antioxidants; Apoptosis; Autophagy; Biomarkers; Chromatography, Liquid; Cyclosporine; Cytoprotection; Drug Interactions; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Oxidative Stress; Phytotherapy; Plant Extracts; Plants, Medicinal; Rats, Sprague-Dawley; Schisandra; Tandem Mass Spectrometry | 2015 |
Deletion of mineralocorticoid receptors in smooth muscle cells blunts renal vascular resistance following acute cyclosporine administration.
Topics: Animals; Calcium Channels, L-Type; Cyclosporine; Endothelium, Vascular; Female; Gene Knockout Techniques; Immunosuppressive Agents; Kidney Diseases; Mice, Inbred C57BL; Mice, Transgenic; Muscle, Smooth, Vascular; Receptors, Mineralocorticoid; Vascular Resistance | 2016 |
Calcineurin-inhibition Results in Upregulation of Local Renin and Subsequent Vascular Endothelial Growth Factor Production in Renal Collecting Ducts.
Topics: Amides; Animals; Biomarkers; Calcineurin Inhibitors; Capillaries; Collagen Type I; Creatinine; Cyclosporine; Cytoprotection; Disease Models, Animal; Fibrosis; Flow Cytometry; Fumarates; Immunosuppressive Agents; Kidney Diseases; Kidney Tubules, Collecting; Male; Mice, Inbred C57BL; Microscopy, Fluorescence, Multiphoton; Real-Time Polymerase Chain Reaction; Renal Circulation; Renin; Renin-Angiotensin System; Tacrolimus; Time Factors; Up-Regulation; Vascular Endothelial Growth Factor A | 2016 |
Cyclosporine A protects podocytes by regulating WAVE1 phosphorylation.
Topics: Actins; Animals; Calcineurin; Calcineurin Inhibitors; Cyclosporine; Gene Expression Regulation; Humans; Kidney Diseases; Mice; Microfilament Proteins; Phosphorylation; Podocytes; Puromycin Aminonucleoside; Visual Cortex; Wiskott-Aldrich Syndrome Protein Family | 2015 |
Beneficial effects of nilotinib, tyrosine kinase inhibitor on cyclosporine-A induced renal damage in rats.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Cyclosporine; Fibrosis; Kidney; Kidney Diseases; Male; NF-kappa B; Oxidative Stress; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Superoxide Dismutase | 2016 |
Graeme Catto: Resilient, realistic, interested.
Topics: Allergy and Immunology; Antifungal Agents; Cyclosporine; Faculty, Medical; Government Agencies; Humans; Kidney Diseases; Kidney Transplantation; Leadership; London; Physicians; Right to Die; United Kingdom; United States | 2016 |
Influence of cyclosporine A on glomerular growth and the effect of mizoribine and losartan on cyclosporine nephrotoxicity in young rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclosporine; Histocytochemistry; Kidney; Kidney Diseases; Kidney Glomerulus; Losartan; Male; Rats, Sprague-Dawley; Ribonucleosides | 2016 |
Role of mesenchymal stem cells versus angiotensin converting enzyme inhibitor in kidney repair.
Topics: Adipogenesis; Adipose Tissue; Angiotensin-Converting Enzyme Inhibitors; Animals; Biomarkers; Bone Marrow Cells; Cell Lineage; Cell Transdifferentiation; Cells, Cultured; Chondrogenesis; Cyclosporine; Disease Models, Animal; Female; Kidney; Kidney Diseases; Lisinopril; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Osteogenesis; Rats, Wistar; Regeneration; Sex-Determining Region Y Protein; Time Factors | 2017 |
Prognostic factors for the evolution and reversibility of chronic rejection in pediatric liver transplantation.
Topics: Adolescent; Biopsy; Child; Child, Preschool; Chronic Disease; Cyclosporine; Female; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Infant; Kidney Diseases; Liver Transplantation; Male; Multivariate Analysis; Mycophenolic Acid; Prognosis; Remission Induction; Survival Rate; Tacrolimus | 2016 |
Clinical experience of conversion from cyclosporine to tacrolimus prolonged-release in stabilized kidney transplant patients.
Topics: Cyclosporine; Delayed-Action Preparations; Diabetic Nephropathies; Dose-Response Relationship, Drug; Drug Substitution; Dyslipidemias; Female; Gingival Hyperplasia; Glomerular Filtration Rate; Hirsutism; Humans; Hypertension, Renal; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Tacrolimus; Treatment Outcome | 2016 |
Calcineurin Inhibitor Nephrotoxicity in the Era of Antibody-Mediated Rejection.
Topics: Calcineurin Inhibitors; Cyclosporine; Graft Rejection; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation | 2016 |
Calcineurin Inhibitor Nephrotoxicity Through the Lens of Longitudinal Histology: Comparison of Cyclosporine and Tacrolimus Eras.
Topics: Adult; Biopsy; Calcineurin Inhibitors; Cyclosporine; Disease Progression; Female; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Incidence; Intention to Treat Analysis; Kaplan-Meier Estimate; Kidney; Kidney Diseases; Kidney Transplantation; Longitudinal Studies; Male; New South Wales; Prevalence; Proportional Hazards Models; Risk Factors; Tacrolimus; Time Factors; Treatment Outcome | 2016 |
Stress Response Gene Nupr1 Alleviates Cyclosporin A Nephrotoxicity In Vivo.
Topics: Animals; Cyclosporine; DNA-Binding Proteins; Humans; Kidney Diseases; Mice; Neoplasm Proteins; Stress, Physiological | 2017 |
British Association of Dermatologists' guidelines for the safe and effective prescribing of methotrexate for skin disease 2016.
Topics: Adult; Alcohol Drinking; Biological Products; Bone Marrow Diseases; Checklist; Chemical and Drug Induced Liver Injury; Chickenpox; Child; Counseling; Cyclosporine; Dermatologic Agents; Drug Administration Routes; Drug Administration Schedule; Drug Approval; Drug Interactions; Drug Monitoring; Drug Overdose; Evidence-Based Medicine; Female; Hepatitis, Viral, Human; HIV Infections; Humans; Intraoperative Complications; Kidney Diseases; Lung Diseases; Methotrexate; Nausea; Neoplasms; Off-Label Use; Patient Education as Topic; Patient Safety; Pregnancy; Pregnancy Complications; Retinoids; Skin Diseases; Tuberculosis; Ultraviolet Rays; Vaccination | 2016 |
A case of intravenous immunoglobulin-dependent chronic inflammatory demyelinating polyneuropathy of pure motor form responsive to mycophenolate mofetil therapy.
Topics: Aged; Chronic Disease; Cyclosporine; Drug Therapy, Combination; Guillain-Barre Syndrome; Humans; Immunoglobulins, Intravenous; Kidney Diseases; Male; Mycophenolic Acid; Recurrence; Secondary Prevention; Time Factors; Treatment Outcome | 2016 |
Effects of Angiotensin II Receptor Blockade on Soluble Klotho and Oxidative Stress in Calcineurin Inhibitor Nephrotoxicity in Rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Angiotensin Receptor Antagonists; Animals; Calcineurin Inhibitors; Cyclosporine; Deoxyguanosine; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Glucuronidase; Kidney; Kidney Diseases; Klotho Proteins; Malondialdehyde; Oxidative Stress; Random Allocation; Rats; Rats, Sprague-Dawley; Spectrophotometry; Valsartan | 2016 |
Late spontaneous decapsulation of the kidney graft in a patient with hepatitis C and treated with sirolimus: possible pathophysiological association in a rare complication.
Topics: Antiviral Agents; Cyclosporine; Drug Substitution; Graft Rejection; Hepatitis C, Chronic; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Postoperative Complications; Prednisolone; Risk Factors; Sirolimus; Tomography, X-Ray Computed | 2017 |
The Usefulness of Determining Neutrophil Gelatinase-Associated Lipocalin Concentration Excreted in the Urine in the Evaluation of Cyclosporine A Nephrotoxicity in Children with Nephrotic Syndrome.
Topics: Adolescent; Biomarkers; Child; Child, Preschool; Cyclosporine; Drug Monitoring; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Kidney Diseases; Lipocalin-2; Male; Nephrotic Syndrome; Prognosis | 2016 |
Effect of kremezin on early-phase renal dysfunction during treatment with cyclosporin A in systemic autoimmune diseases.
Topics: Aged; Autoimmune Diseases; Carbon; Creatinine; Cyclosporine; Dose-Response Relationship, Drug; Female; Glomerular Filtration Rate; Humans; Kidney Diseases; Male; Middle Aged; Oxides | 2008 |
FK778 ameliorates post-transplant expression of fibrogenic growth factors and development of chronic rejection changes in rat kidney allografts.
Topics: Alkynes; Animals; Calcineurin Inhibitors; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cyclosporine; Disease Models, Animal; Dose-Response Relationship, Drug; Graft Rejection; Immunosuppressive Agents; Isoxazoles; Kidney Diseases; Kidney Transplantation; Male; Nitriles; Platelet-Derived Growth Factor; Rats; Rats, Inbred WF; Risk Factors; Tacrolimus; Transforming Growth Factor beta; Transplantation, Homologous | 2008 |
An interleukin-6-neutralizing antibody prevents cyclosporine-induced nephrotoxicity in mice.
Topics: Acetophenones; Animals; Antibodies, Monoclonal; Cyclosporine; Diet, Sodium-Restricted; Disease Models, Animal; Immunosuppressive Agents; Interleukin-6; Kidney; Kidney Diseases; Kidney Tubules; Male; Mice; Mice, Inbred C57BL; NADPH Oxidases; Necrosis | 2008 |
Comparative analysis of azathioprine versus cyclosporine-based therapy in primary haplo-identical live-donor kidney transplantation: a 20-year experience.
Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Cyclosporine; Drug Therapy, Combination; Egypt; Female; Graft Survival; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Living Donors; Male; Retrospective Studies; Survival Analysis | 2008 |
Protective effect of Epo on oxidative renal injury in rats with cyclosporine nephrotoxicity.
Topics: Animals; Apoptosis; Body Weight; Cyclosporine; Dose-Response Relationship, Drug; Erythropoietin; Female; Hematopoiesis; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Function Tests; Lipid Peroxidation; Oxidative Stress; Rats; Rats, Wistar; Recombinant Proteins | 2008 |
The role of macrophage in the pathogenesis of chronic cyclosporine-induced nephropathy.
Topics: Animals; Apoptosis; Chronic Disease; Clodronic Acid; Cyclosporine; Immunity, Innate; Immunosuppressive Agents; Kidney; Kidney Diseases; Liposomes; Macrophages; Male; Rats; Rats, Sprague-Dawley | 2008 |
Impact of cyclosporine A on magnesium homeostasis: clinical observation in lung transplant recipients and experimental study in mice.
Topics: Administration, Oral; Adolescent; Adult; Animals; Creatinine; Cyclosporine; Dietary Supplements; Disease Models, Animal; Female; Homeostasis; Humans; Immunosuppressive Agents; Kidney Diseases; Lung Transplantation; Magnesium; Magnesium Deficiency; Male; Mice; Mice, Inbred C57BL; Middle Aged; Pyrrolidonecarboxylic Acid; Retrospective Studies; Time Factors; Treatment Failure | 2008 |
Long-term graft outcome in patients with chronic allograft nephropathy after immunosuppression modifications.
Topics: Adult; Azathioprine; Chronic Disease; Cyclosporine; Disease Progression; Drug Therapy, Combination; Female; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Kaplan-Meier Estimate; Kidney Diseases; Kidney Function Tests; Kidney Transplantation; Male; Middle Aged; Mycophenolic Acid; Retrospective Studies; Tacrolimus; Time Factors; Transplantation, Homologous; Treatment Outcome | 2009 |
Infiltration of nestin-expressing cells in interstitial fibrosis in chronic cyclosporine nephropathy.
Topics: Cyclosporine; Cystitis, Interstitial; Humans; Immunosuppressive Agents; Intermediate Filament Proteins; Kidney; Kidney Diseases; Nerve Tissue Proteins; Nestin; Organ Preservation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2008 |
Expression of ammonia transporters, Rhbg and Rhcg, in chronic cyclosporine nephropathy in rats.
Topics: Animals; Cation Transport Proteins; Cyclosporine; Kidney Diseases; Male; Membrane Glycoproteins; Rats; Rats, Sprague-Dawley | 2008 |
Therapeutic equivalence and mg:mg switch ability of a generic cyclosporine microemulsion formulation (Sigmasporin Microral) in stable renal transplant patients maintained on Sandimmun Neoral.
Topics: Adult; Chemistry, Pharmaceutical; Cyclosporine; Drugs, Generic; Emulsions; Female; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged | 2008 |
Arterial stiffness after successful renal transplantation.
Topics: Adult; Carotid Arteries; Cyclosporine; Female; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Living Donors; Male; Middle Aged; Pulse; Tacrolimus; Tunica Intima; Tunica Media; Ultrasonography | 2008 |
Effects of tomato extract on oxidative stress induced toxicity in different organs of rats.
Topics: Acetaminophen; Amiodarone; Analgesics, Non-Narcotic; Animals; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Cyclosporine; Glutathione; Immunosuppressive Agents; Kidney Diseases; Lipid Peroxidation; Lung Diseases; Male; Oxidative Stress; Plant Extracts; Rats; Rats, Sprague-Dawley; Solanum lycopersicum | 2008 |
Successful outcome after nonmyeloablative allogeneic hematopoietic stem cell transplantation in patients with renal dysfunction.
Topics: Adult; Aged; Antineoplastic Agents; Cyclosporine; Disease-Free Survival; Female; Glomerular Filtration Rate; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Kidney Diseases; Male; Middle Aged; Mycophenolic Acid; Survival Rate; Transplantation Conditioning; Transplantation, Homologous; Vidarabine; Whole-Body Irradiation | 2008 |
CNIs: immediate benefits but storing problems for the future?
Topics: Age Factors; Calcineurin Inhibitors; Cyclosporine; Drug Administration Schedule; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Function Tests; Liver Transplantation; Secondary Prevention; Tacrolimus; Time Factors; Treatment Outcome | 2008 |
Conversion to sirolimus of patients with chronic allograft nephropathy--a retrospective analysis of outcome and influencing factors.
Topics: Adult; Calcineurin Inhibitors; Cohort Studies; Cyclosporine; Female; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Retrospective Studies; Risk Factors; Sirolimus; Treatment Outcome | 2009 |
Sirolimus monotherapy effectiveness in liver transplant recipients with renal dysfunction due to calcineurin inhibitors.
Topics: Adult; Aged; Blood Glucose; Calcineurin Inhibitors; Cohort Studies; Creatinine; Cyclosporine; Glomerular Filtration Rate; Humans; Hypercholesterolemia; Hypertriglyceridemia; Immunosuppressive Agents; Kidney; Kidney Diseases; Liver Transplantation; Male; Middle Aged; Sirolimus; Tacrolimus; Treatment Outcome | 2009 |
Autophagy: a protective mechanism against nephrotoxicant-induced renal injury.
Topics: Autophagy; Cisplatin; Cyclosporine; Humans; Kidney Diseases | 2009 |
Determination of Clara cell protein urinary elimination as a marker of tubular dysfunction.
Topics: Acetylglucosaminidase; Adolescent; beta 2-Microglobulin; Biomarkers; Child; Child, Preschool; Creatinine; Cyclosporine; Female; Humans; Immunosuppressive Agents; Infant; Kidney Diseases; Kidney Failure, Chronic; Kidney Tubules, Proximal; Male; Uteroglobin; Young Adult | 2009 |
Chronic kidney disease after heart transplantation.
Topics: Adolescent; Adult; Aged; Chronic Disease; Cyclosporine; Dose-Response Relationship, Drug; Female; Graft Rejection; Heart Transplantation; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Failure, Chronic; Male; Middle Aged; Prospective Studies; Retrospective Studies; Risk Factors; Young Adult | 2009 |
The top 10 things nephrologists wish every primary care physician knew.
Topics: Aluminum; Anemia; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antacids; Blood Pressure; Blood Urea Nitrogen; Cardiovascular Diseases; Cathartics; Chronic Disease; Contraindications; Creatinine; Cyclosporine; Disease Progression; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Erythropoietin; Evidence-Based Medicine; Glomerular Filtration Rate; Humans; Hypertension; Immunosuppressive Agents; Kidney Diseases; Magnesium; Nephrolithiasis; Nephrology; Phosphates; Primary Health Care; Proteinuria; Recombinant Proteins; Referral and Consultation; Tacrolimus; Urinalysis | 2009 |
Polyomavirus BK and JC infections in well matched Finnish kidney transplant recipients.
Topics: Adolescent; Adult; BK Virus; Cyclosporine; Female; Finland; Humans; Immunosuppressive Agents; JC Virus; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Polyomavirus Infections; Treatment Outcome | 2009 |
Successful oral cyclosporin therapy for Henoch-Schönlein purpura nephropathy.
Topics: Adult; Cyclosporine; Humans; IgA Vasculitis; Immunosuppressive Agents; Kidney Diseases; Male | 2009 |
Reversible Parkinsonism after chronic cyclosporin treatment in renal transplantation.
Topics: Cyclosporine; Female; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Middle Aged; Parkinsonian Disorders | 2009 |
Renal function and cardiovascular risk profile after conversion from ciclosporin to tacrolimus: prospective study in 80 liver transplant recipients.
Topics: Adult; Aged; Cardiovascular Diseases; Chronic Disease; Cyclosporine; Disease Progression; Female; Follow-Up Studies; Graft Survival; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Function Tests; Liver Diseases; Liver Transplantation; Male; Middle Aged; Prospective Studies; Risk Factors; Tacrolimus; Treatment Outcome | 2009 |
Risk factors for cyclosporin A nephrotoxicity in children with steroid-dependant nephrotic syndrome.
Topics: Adolescent; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Biopsy; Child; Child, Preschool; Cyclosporine; Disease Progression; Female; Humans; Hypertension; Hyperuricemia; Immunosuppressive Agents; Infant; Kidney Diseases; Logistic Models; Male; Nephrotic Syndrome; Odds Ratio; Retrospective Studies; Risk Assessment; Risk Factors; Severity of Illness Index; Time Factors; Treatment Outcome | 2009 |
Transfer from ciclosporin to mycophenolate-sirolimus immunosuppression for chronic renal disease after heart transplantation: safety and efficacy of two regimens.
Topics: Chronic Disease; Cyclosporine; Female; Heart Transplantation; Humans; Immunosuppressive Agents; Kidney Diseases; Male; Middle Aged; Mycophenolic Acid; Postoperative Complications; Retrospective Studies; Sirolimus | 2009 |
Protective effects of Mizoribine on Cyclosporine A nephropathy in rats.
Topics: Animals; Anti-Inflammatory Agents; Body Weight; Cyclosporine; Disease Progression; Fibrosis; Immunohistochemistry; Immunosuppressive Agents; Inflammation; Kidney; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Ribonucleosides | 2009 |
Expression of transforming growth factor-beta and determination of apoptotic index in histopathological sections for assessment of the effects of Apigenin (4', 5', 7'- Trihydroxyflavone) on Cyclosporine A induced renal damage.
Topics: Administration, Oral; Animals; Apigenin; Apoptosis; Cell Count; Cyclosporine; Drug Antagonism; Immunohistochemistry; Immunosuppressive Agents; Injections, Intraperitoneal; Kidney; Kidney Diseases; Kidney Glomerulus; Kidney Tubules; Male; Organ Size; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta | 2009 |
Renoprotective immunosuppression by pioglitazone with low-dose cyclosporine in rat heart transplantation.
Topics: Animals; Apoptosis; Cardiotonic Agents; Cyclosporine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Gastric Lavage; Graft Rejection; Graft Survival; Heart Transplantation; Immunosuppressive Agents; Injections, Subcutaneous; Interferon-gamma; Interleukin-2; Kidney Diseases; Kidney Function Tests; Male; Peptide Fragments; Pioglitazone; Protective Agents; Random Allocation; Rats; Thiazolidinediones; Transplantation, Heterotopic | 2009 |
Long-term immunosuppression with anti-CD25 monoclonal antibodies in heart transplant patients with chronic kidney disease.
Topics: Adult; Aged; Antibodies, Monoclonal; Cyclosporine; Follow-Up Studies; Heart Transplantation; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Interleukin-2 Receptor alpha Subunit; Kidney Diseases; Kidney Failure, Chronic; Middle Aged | 2009 |
Serum indoxyl sulfate as an early marker for detecting chronic cyclosporine nephrotoxicity.
Topics: Adolescent; Biomarkers; Child; Child, Preschool; Chronic Disease; Cyclosporine; Early Diagnosis; Female; Humans; Immunosuppressive Agents; Indican; Kidney Diseases; Male; Young Adult | 2010 |
Protective effect of caffeic acid phenethyl ester on cyclosporine A-induced nephrotoxicity in rats.
Topics: Animals; Antioxidants; Caffeic Acids; Cyclosporine; Disease Models, Animal; Female; Immunosuppressive Agents; Kidney; Kidney Diseases; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar | 2009 |
[Minimize kidney failure in transplantation patients with proliferation signal inhibitors].
Topics: Calcineurin Inhibitors; Cyclosporine; Glomerular Filtration Rate; Graft Rejection; Humans; Immunosuppressive Agents; Intracellular Signaling Peptides and Proteins; Kidney Diseases; Kidney Transplantation; Liver Transplantation; Postoperative Complications; Protein Serine-Threonine Kinases; Proteinuria; Renal Insufficiency; Sirolimus; TOR Serine-Threonine Kinases | 2009 |
[Side effects of proliferation signal inhibitors and their management].
Topics: Angioedema; Calcineurin Inhibitors; Cicatrix; Cyclosporine; Graft Rejection; Graft Survival; Hematologic Diseases; Humans; Hyperlipidemias; Immunosuppressive Agents; Intracellular Signaling Peptides and Proteins; Kidney Diseases; Lymphocele; Pneumonia; Protein Serine-Threonine Kinases; Sirolimus; Skin Diseases; TOR Serine-Threonine Kinases | 2009 |
Impact of reduced nephron mass on cyclosporine- and/or sirolimus-induced nephrotoxicity.
Topics: Animals; Aquaporin 2; Cell Adhesion Molecules; Creatinine; Cyclosporine; Disease Models, Animal; Follow-Up Studies; Gene Expression Regulation; Immunosuppressive Agents; Kidney Diseases; Male; Nephrons; Polymerase Chain Reaction; Rats; Risk Factors; RNA, Messenger; Sirolimus; Sodium-Phosphate Cotransporter Proteins | 2009 |
[Effects of urokinase on renal interstitial fibrosis and transforming growth factor-beta1 in the kidney of rats with chronic cyclosporine A nephropathy].
Topics: Animals; Cyclosporine; Fibrosis; Kidney; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1; Urokinase-Type Plasminogen Activator | 2009 |
BK-virus and the impact of pre-emptive immunosuppression reduction: 5-year results.
Topics: Azathioprine; BK Virus; Cyclosporine; Graft Survival; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Kidney Diseases; Kidney Function Tests; Tacrolimus; Viremia | 2010 |
Neutrophil gelatinase-associated lipocalin (NGAL): a new marker of cyclosporine nephrotoxicity?
Topics: Acute-Phase Proteins; Adolescent; Biomarkers; Case-Control Studies; Child; Child, Preschool; Creatinine; Cyclosporine; Drug Monitoring; Drug Therapy, Combination; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunosuppressive Agents; Kidney Diseases; Lipocalin-2; Lipocalins; Male; Nephrotic Syndrome; Predictive Value of Tests; Proteinuria; Proto-Oncogene Proteins; ROC Curve; Steroids; Treatment Outcome | 2010 |
Polymerized type I collagen reduces chronic cyclosporine nephrotoxicity.
Topics: Actins; Animals; Cell Adhesion Molecules; Collagen Type I; Cyclosporine; Disease Models, Animal; Immunosuppressive Agents; Injections, Intraperitoneal; Kidney; Kidney Diseases; Male; Oxidative Stress; Polymers; Rats; Rats, Wistar; Transforming Growth Factor beta | 2010 |
Conversion of cyclosporine to sirolimus before 12 months is associated with marked improvement in renal function and low proteinuria in a South African renal transplant population.
Topics: Clinical Audit; Cyclosporine; Female; Glomerular Filtration Rate; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Male; Proteinuria; Retrospective Studies; Sirolimus; South Africa; Time Factors; Treatment Outcome | 2010 |
Paricalcitol attenuates cyclosporine-induced kidney injury in rats.
Topics: Animals; Apoptosis; Cyclosporine; Ergocalciferols; Fibrosis; Inflammation; Kidney Diseases; Protective Agents; Rats; Signal Transduction; Treatment Outcome | 2010 |
Belatacept: the promises and challenges of belatacept and costimulatory blockade.
Topics: Abatacept; Calcineurin Inhibitors; Clinical Trials, Phase III as Topic; Cyclosporine; Graft Rejection; Graft Survival; Humans; Immunoconjugates; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Treatment Outcome | 2010 |
Posttransplantation calcineurin inhibitor-induced hemolytic uremic syndrome: single-center experience.
Topics: Adaptor Proteins, Signal Transducing; Adolescent; Adult; Anemia; Antilymphocyte Serum; Child; Complement C4b; Creatinine; Cyclosporine; Erythrocytes; Female; Hemoglobins; Hemolytic-Uremic Syndrome; Histocompatibility Testing; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Peptide Fragments; Platelet Count; Postoperative Complications; Retrospective Studies; Thrombocytopenia | 2010 |
Upregulation of hyaluronan and its binding receptors in an experimental model of chronic cyclosporine nephropathy.
Topics: Actins; Animals; Chronic Disease; Cyclosporine; Diet, Sodium-Restricted; Disease Models, Animal; Fibrosis; Hyaluronan Receptors; Hyaluronic Acid; Immunohistochemistry; Kidney; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Time Factors; Up-Regulation | 2010 |
Interaction of endothelin-1 and nitric oxide pathways in human tubular epithelial cells under the influence of cyclosporine-A.
Topics: Biosynthetic Pathways; Cells, Cultured; Cyclosporine; Endothelin-1; Epithelial Cells; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Tubules; Nitric Oxide; Nitric Oxide Synthase | 2010 |
Predicting medication adherence and employment status following kidney transplant: The relative utility of traditional and everyday cognitive approaches.
Topics: Activities of Daily Living; Adult; Cognition Disorders; Cyclosporine; Employment; Executive Function; Female; Humans; Kidney Diseases; Kidney Transplantation; Longitudinal Studies; Male; Medication Adherence; Memory; Middle Aged; Neuropsychological Tests; Predictive Value of Tests; Problem Solving; Regression Analysis; Retrospective Studies; Self Concept; Surveys and Questionnaires; Tacrolimus; Verbal Learning | 2010 |
Pargyline reduces renal damage associated with ischaemia-reperfusion and cyclosporin.
Topics: Animals; Cyclosporine; Disease Models, Animal; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Monoamine Oxidase Inhibitors; Oxidative Stress; Pargyline; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury | 2011 |
Protective effect of trapidil and l-arginine against renal and hepatic toxicity induced by cyclosporine in rats.
Topics: Animals; Arginine; Chemical and Drug Induced Liver Injury; Cyclosporine; Immunosuppressive Agents; Kidney Diseases; Male; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Trapidil; Vasodilator Agents | 2010 |
Angiotensin II blockade upregulates the expression of Klotho, the anti-ageing gene, in an experimental model of chronic cyclosporine nephropathy.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aging; Angiotensin II; Animals; Blotting, Western; Chronic Disease; Cyclosporine; Deoxyguanosine; Disease Models, Animal; Glucuronidase; Immunoenzyme Techniques; Immunosuppressive Agents; Kidney Diseases; Klotho Proteins; Male; Mice; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation; Vasoconstrictor Agents | 2011 |
Sustained renal response to mycophenolate mofetil and CNI taper promotes survival in liver transplant patients with CNI-related renal dysfunction.
Topics: Adult; Calcineurin Inhibitors; Cyclosporine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Graft Rejection; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Function Tests; Liver Transplantation; Male; Middle Aged; Multivariate Analysis; Mycophenolic Acid; Postoperative Complications; Prospective Studies; Retrospective Studies; Survival Rate; Tacrolimus | 2011 |
Potential adverse effects of cyclosporin A on kidneys after spinal cord injury.
Topics: Animals; Cell Transplantation; Cyclosporine; Disease Models, Animal; Drug Therapy, Combination; Graft Rejection; Immunosuppressive Agents; Kidney Diseases; Male; Rats; Rats, Wistar; Spinal Cord Injuries; Treatment Outcome | 2011 |
Cyclosporine-induced changes in drug metabolizing enzymes in hyperlipemic rabbit kidneys could explain its toxicity.
Topics: Animals; Antioxidants; Cholesterol, Dietary; Creatinine; Cyclosporine; Cytochrome P-450 CYP2E1; Female; Glutathione; Hyperlipidemias; Immunosuppressive Agents; Kidney; Kidney Diseases; Lipid Peroxidation; Lipids; Oxidative Stress; Rabbits; Reactive Oxygen Species; Urea | 2010 |
Early and delayed effects of AST-120 on chronic cyclosporine nephropathy.
Topics: Animals; Blotting, Northern; Blotting, Western; Carbon; Chronic Disease; Cyclosporine; Disease Progression; Immunoenzyme Techniques; Immunosuppressive Agents; In Situ Hybridization; Kidney Diseases; Male; Microspheres; Oxidative Stress; Oxides; Rats; Rats, Sprague-Dawley | 2011 |
Renoprotective effects of green tea extract on renin-angiotensin-aldosterone system in chronic cyclosporine-treated rats.
Topics: Aldosterone; Animals; Blotting, Western; Creatinine; Cyclosporine; Immunosuppressive Agents; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Tea | 2011 |
Conversion to combined mycophenolate mofetil and low-dose calcineurin inhibitor therapy for renal dysfunction in liver transplant patients: never too late?
Topics: Calcineurin Inhibitors; Cyclosporine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Liver Transplantation; Mycophenolic Acid; Postoperative Complications; Tacrolimus | 2011 |
Caffeic acid phenethyl ester protects against oxidative stress-related renal dysfunction in rats treated with cyclosporin A.
Topics: Acute Kidney Injury; Animals; Antioxidants; Blood Urea Nitrogen; Body Weight; Caffeic Acids; Creatinine; Cyclosporine; Disease Models, Animal; Drug Evaluation, Preclinical; Feeding Behavior; Glutathione; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Malondialdehyde; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; Superoxide Dismutase | 2011 |
Comment: management of hypertension in renal transplant patients: a comprehensive review of nonpharmacologic and pharmacologic treatment strategies.
Topics: Animals; Antihypertensive Agents; Cyclosporine; Graft Rejection; Humans; Hypertension; Kidney Diseases; Kidney Transplantation | 2010 |
Cardioprotective effect of calcineurin inhibition in an animal model of renal disease.
Topics: Animals; Calcineurin Inhibitors; Chronic Disease; Cyclosporine; Heart Diseases; Hypertrophy, Left Ventricular; Immunosuppressive Agents; Kidney Diseases; Male; Nephrectomy; Random Allocation; Rats; Rats, Sprague-Dawley; Tacrolimus; Ventricular Remodeling | 2011 |
Impact of immunosuppressive therapy on hepatitis C infection after renal transplantation.
Topics: Adult; Aged; Calcineurin Inhibitors; Cyclosporine; Female; Germany; Graft Survival; Hepacivirus; Hepatitis C, Chronic; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Liver Cirrhosis; Liver Function Tests; Male; Middle Aged; Retrospective Studies; RNA, Viral; Tacrolimus; Time Factors; Transaminases; Treatment Outcome; Viral Load; Virus Replication | 2011 |
Protective effect of docosahexaenoic acid against cyclosporine A-induced nephrotoxicity in rats: a possible mechanism of action.
Topics: Animals; Cyclosporine; Docosahexaenoic Acids; Immunosuppressive Agents; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley | 2011 |
Early short-term imatinib treatment is sufficient to prevent the development of chronic allograft nephropathy.
Topics: Animals; Antineoplastic Agents; Benzamides; Chronic Disease; Cyclosporine; Imatinib Mesylate; Immunoenzyme Techniques; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Piperazines; Platelet-Derived Growth Factor; Pyrimidines; Rats; Rats, Inbred Strains; Time Factors; Transplantation, Homologous | 2011 |
Ceftriaxone ameliorates cyclosporine A-induced oxidative nephrotoxicity in rat.
Topics: Animals; Antioxidants; Ceftriaxone; Cyclosporine; Disease Models, Animal; Female; Humans; Kidney; Kidney Diseases; Oxidative Stress; Rats; Rats, Wistar | 2011 |
Sirolimus prevents short-term renal changes induced by ischemia-reperfusion injury in rats.
Topics: Animals; Cyclosporine; Glomerular Filtration Rate; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Function Tests; Male; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sirolimus; Tacrolimus | 2011 |
Reno-protective role of flunarizine (mitochondrial permeability transition pore inactivator) against gentamicin induced nephrotoxicity in rats.
Topics: Animals; Body Weight; Cyclosporine; Flunarizine; Gentamicins; Kidney Diseases; Male; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Rats; Rats, Sprague-Dawley | 2011 |
[Inhibitory effect of chailing decoction on renal tubular epithelial phenotype transformation in rats with cyclosporine A-induced nephropathy].
Topics: Actins; Animals; Collagen Type III; Cyclosporine; Drugs, Chinese Herbal; Epithelial Cells; Fibrosis; Kidney Diseases; Kidney Tubules; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1 | 2011 |
Predictive factors for ciclosporin-associated nephrotoxicity in children with minimal change nephrotic syndrome.
Topics: Adolescent; Child; Child, Preschool; Cyclosporine; Female; Humans; Immunosuppressive Agents; Infant; Kidney Diseases; Male; Nephrosis, Lipoid; Risk Factors | 2011 |
BK viremia surveillance after kidney transplant: single-center experience during a change from cyclosporine-to lower-dose tacrolimus-based primary immunosuppression regimen.
Topics: BK Virus; Cyclosporine; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Mycophenolic Acid; Polyomavirus Infections; Prednisolone; Tacrolimus; Time Factors; Tumor Virus Infections; Viremia | 2011 |
Rho kinase inhibition by fasudil attenuates cyclosporine-induced kidney injury.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cells, Cultured; Cyclosporine; Kidney Cortex; Kidney Diseases; Male; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Signal Transduction | 2011 |
Is arteriolar vacuolization a predictor of calcineurin inhibitor nephrotoxicity?
Topics: Arterioles; Calcineurin Inhibitors; Cyclosporine; Female; Graft Rejection; Humans; Hyalin; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Living Donors; Male; Middle Aged; Retrospective Studies; Tacrolimus; Vacuoles | 2011 |
Nanoparticulate delivery can improve peroral bioavailability of cyclosporine and match Neoral Cmax sparing the kidney from damage.
Topics: Analysis of Variance; Animals; Area Under Curve; Blood Urea Nitrogen; Brain Chemistry; Creatinine; Cyclosporine; Drug Delivery Systems; Histocytochemistry; Kidney; Kidney Diseases; Liver; Male; Nanoparticles; Particle Size; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Tissue Distribution; Toxicity Tests, Chronic | 2011 |
[Update on psoriasis at the Dermatology Day conference, Paris 2010].
Topics: Comorbidity; Creatinine; Cyclosporine; Dermatologic Agents; Dose-Response Relationship, Drug; Humans; Kidney Diseases; Liver Cirrhosis; Methotrexate; Psoriasis; Risk Factors; Severity of Illness Index | 2011 |
Epithelial-to-mesenchymal transition predicts cyclosporine nephrotoxicity in renal transplant recipients.
Topics: Adult; Cyclosporine; Epithelial-Mesenchymal Transition; Female; Glomerular Filtration Rate; Graft Survival; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Predictive Value of Tests; Randomized Controlled Trials as Topic; Retrospective Studies | 2011 |
Chronic calcineurin inhibitor use is nephrotoxic.
Topics: Animals; Calcineurin Inhibitors; Cyclosporine; Dose-Response Relationship, Drug; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Organ Transplantation; Time Factors | 2011 |
Calcineurin inhibitors: short-term friend, long-term foe?
Topics: Calcineurin Inhibitors; Cyclosporine; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Organ Transplantation; Time Factors | 2011 |
Effects of erdosteine on cyclosporin-A-induced nephrotoxicity.
Topics: Animals; Antioxidants; Catalase; Cyclosporine; Glutathione Peroxidase; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Malondialdehyde; Nitric Oxide; Oxidative Stress; Rats; Rats, Wistar; Superoxide Dismutase; Thioglycolates; Thiophenes | 2012 |
Kidney-specific deletion of multidrug resistance-related protein 2 does not aggravate acute cyclosporine A nephrotoxicity in rats.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood Pressure; Cyclosporine; Gene Deletion; Gene Expression Regulation; Glomerular Filtration Rate; Glutathione Disulfide; Hemodynamics; Kidney; Kidney Cortex; Kidney Diseases; Male; Organ Specificity; Polymerase Chain Reaction; Rats; RNA, Messenger; Superoxides | 2012 |
Histological characteristics of calcineurin inhibitor toxicity--there is no such thing as specificity!
Topics: Arterioles; Biomarkers; Cyclosporine; Female; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male | 2011 |
Specificity of histological markers of long-term CNI nephrotoxicity in kidney-transplant recipients under low-dose cyclosporine therapy.
Topics: Adult; Arterioles; Biomarkers; Cyclosporine; Female; Glomerular Filtration Rate; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Function Tests; Kidney Transplantation; Male; Prognosis; Retrospective Studies; Survival Rate | 2011 |
Metoprolol ameliorates cyclosporine a-induced hypertension and nephrotoxicity in rats.
Topics: Adrenergic beta-1 Receptor Antagonists; Animals; Antioxidants; Blood Pressure; Carbachol; Cyclosporine; Cytokines; Endothelium, Vascular; Hypertension; Immunosuppressive Agents; Kidney Diseases; Male; Metoprolol; Oxidative Stress; Rats; Rats, Wistar | 2011 |
[Expression and mechanism of osteoactivin in the kidney of SD rats after acute cyclosporine A toxicity].
Topics: Animals; Collagen Type III; Cyclosporine; Epithelial Cells; Immunosuppressive Agents; Kidney Diseases; Kidney Tubules; Male; Matrix Metalloproteinase 13; Membrane Glycoproteins; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2011 |
Chronic graft dysfunction and improvement by cytokine response modifier a protein transfection.
Topics: Apoptosis; Blotting, Western; Cell Line; Cell Survival; Cyclosporine; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Kidney Tubules, Proximal; Real-Time Polymerase Chain Reaction; RNA, Messenger; Serpins; Time Factors; Transfection; Viral Proteins | 2011 |
Hydrocortisone attenuates cyclosporin A-induced nephrotoxicity in rats.
Topics: Animals; Apoptosis; Blood Pressure; Catalase; Cholesterol; Creatinine; Cyclosporine; Glutathione Peroxidase; Hydrocortisone; Immunosuppressive Agents; Kidney Diseases; Lipid Peroxidation; Male; Rats; Rats, Wistar; Superoxide Dismutase; Urea | 2012 |
Renal dysfunction in a renal transplant patient treated concurrently with cyclosporine and imatinib.
Topics: Aged; Antineoplastic Agents; Benzamides; Cyclosporine; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Piperazines; Protein Kinase Inhibitors; Pyrimidines | 2012 |
Use of uric acid-lowering agents limits experimental cyclosporine nephropathy.
Topics: Allopurinol; Animals; Benzbromarone; Cell Proliferation; Cyclosporine; Enzyme Inhibitors; Fibrosis; Hyperuricemia; Immunohistochemistry; Kidney; Kidney Diseases; Male; Osteopontin; Random Allocation; Rats; Rats, Sprague-Dawley; Uric Acid; Uricosuric Agents; Vascular Endothelial Growth Factor A; Xanthine Oxidase | 2012 |
[Choice of therapy based on clinical setting].
Topics: Age Factors; Comorbidity; Contraindications; Cyclosporine; Decision Making; Dermatologic Agents; Female; Hepatic Insufficiency; Humans; Kidney Diseases; Latent Tuberculosis; Mental Disorders; Methotrexate; Pregnancy; Psoriasis; Risk Factors; Skin Neoplasms | 2011 |
Anti-apoptotic and anti-oxidant effects of grape seed proanthocyanidin extract in preventing cyclosporine A-induced nephropathy.
Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Blood Urea Nitrogen; Creatinine; Cyclosporine; Cytoprotection; Disease Models, Animal; Female; Grape Seed Extract; Kidney; Kidney Diseases; Malondialdehyde; Oxidative Stress; Proanthocyanidins; Rats; Rats, Sprague-Dawley; Time Factors | 2012 |
Cyclosporine microemulsion formulation (sigmasporin microral) effect as first-line immunosuppressant on renal functions at 3 years.
Topics: Adult; Chemistry, Pharmaceutical; Cyclosporine; Drugs, Generic; Emulsions; Female; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Middle East; Prospective Studies; Time Factors; Treatment Outcome; Young Adult | 2012 |
Comparison of early and late conversion of sirolimus in experimental model of chronic cyclosporine nephropathy.
Topics: Animals; Apoptosis; Chronic Disease; Cyclosporine; Immunosuppressive Agents; Intestines; Kidney Diseases; Male; Models, Animal; Rats; Rats, Sprague-Dawley; Sirolimus | 2012 |
Genetic and clinical determinants of early, acute calcineurin inhibitor-related nephrotoxicity: results from a kidney transplant consortium.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcineurin Inhibitors; Cyclosporine; Cytochrome P-450 CYP3A; Female; Follow-Up Studies; Genetic Predisposition to Disease; Genotype; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Polymorphism, Single Nucleotide; Postoperative Complications; Proportional Hazards Models; Prospective Studies; Risk Factors; Tacrolimus; Young Adult | 2012 |
Activation of hypoxia-inducible factor by cobalt is associated with the attenuation of tissue injury and apoptosis in cyclosporine-induced nephropathy.
Topics: Animals; Apoptosis; Cell Line; Cobalt; Cyclosporine; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunosuppressive Agents; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley | 2012 |
Carbamylated erythropoietin ameliorates cyclosporine nephropathy without stimulating erythropoiesis.
Topics: Animals; Apoptosis; Collagen Type I; Cyclosporine; Disease Models, Animal; Dogs; Erythropoiesis; Erythropoietin; Fibrosis; Hemoglobins; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Macrophages; Male; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction; Transforming Growth Factor beta1 | 2012 |
Intraparenchymal injection of bone marrow mesenchymal stem cells reduces kidney fibrosis after ischemia-reperfusion in cyclosporine-immunosuppressed rats.
Topics: Adult; Animals; Bone Marrow Cells; Cyclosporine; Disease Models, Animal; Female; Fibrosis; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Middle Aged; Rats; Rats, Inbred Lew; Reperfusion Injury | 2012 |
New insights on the anti-inflammatory effect of some Egyptian plants against renal dysfunction induced by cyclosporine.
Topics: Animals; Anti-Inflammatory Agents; Arecaceae; Biomarkers; Cyclosporine; Dietary Supplements; Disease Models, Animal; Drug Therapy, Combination; Egypt; Fabaceae; Female; Foeniculum; Fruit; Kidney; Kidney Diseases; Plant Preparations; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Seeds; Time Factors | 2012 |
Protective effect of schisandrin B against cyclosporine A-induced nephrotoxicity in vitro and in vivo.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Apoptosis; Blood Urea Nitrogen; Cell Survival; Creatinine; Cyclooctanes; Cyclosporine; Enzyme Inhibitors; Fruit; Glutathione; Humans; Kidney; Kidney Diseases; L-Lactate Dehydrogenase; Lignans; Male; Malondialdehyde; Mice; Mice, Inbred Strains; Oxidative Stress; Phytotherapy; Plant Extracts; Polycyclic Compounds; Reactive Oxygen Species; Schisandra | 2012 |
Chronic cyclosporine nephropathy is characterized by excessive autophagosome formation and decreased autophagic clearance.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Animals; Antioxidants; Apoptosis; Autophagy; Caspase 3; Cyclosporine; Deoxyguanosine; Dose-Response Relationship, Drug; Ether-A-Go-Go Potassium Channels; Kidney Diseases; Male; Mice; Microscopy, Electron; Microtubule-Associated Proteins; Oxidative Stress; Phagosomes; Pravastatin; Time Factors | 2012 |
ABCB1 polymorphisms are associated with cyclosporine-induced nephrotoxicity and gingival hyperplasia in renal transplant recipients.
Topics: Adult; Analysis of Variance; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chi-Square Distribution; Cyclosporine; Cytochrome P-450 CYP3A; Drug Monitoring; Female; Gene Frequency; Genetic Predisposition to Disease; Gingival Hyperplasia; Graft Rejection; Graft Survival; Haplotypes; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Linear Models; Logistic Models; Male; Middle Aged; Odds Ratio; Pharmacogenetics; Phenotype; Polymorphism, Genetic; Retrospective Studies; Risk Factors | 2013 |
Treatment of pure red-cell aplasia with cyclosporine in a renal transplant patient.
Topics: Cyclosporine; Female; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Mycophenolic Acid; Red-Cell Aplasia, Pure; Tacrolimus; Treatment Outcome; Withholding Treatment; Young Adult | 2013 |
The protective effects of omega 3 fatty acids and sesame oil against cyclosporine A-induced nephrotoxicity.
Topics: Administration, Oral; Albumins; Animals; Antioxidants; Apoptosis; Blood Urea Nitrogen; Cyclosporine; Fatty Acids, Omega-3; Immunosuppressive Agents; Injections, Subcutaneous; Kidney Diseases; Kidney Function Tests; Male; Rats; Rats, Wistar; Sesame Oil | 2013 |
Statin upregulates the expression of klotho, an anti-aging gene, in experimental cyclosporine nephropathy.
Topics: Aging; Animals; Cyclosporine; Glucuronidase; Immunosuppressive Agents; Kidney; Kidney Diseases; Klotho Proteins; Male; Mice; Pravastatin; Up-Regulation | 2012 |
[Protective effects of chailing decoction on cyclosporine A induced chronic renal injury and its mechanisms].
Topics: Animals; Apoptosis; Cell Proliferation; Connective Tissue Growth Factor; Cyclosporine; Drugs, Chinese Herbal; Female; Fibrosis; Kidney; Kidney Diseases; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1 | 2012 |
Rosuvastatin attenuates inflammation, apoptosis and fibrosis in a rat model of cyclosporine-induced nephropathy.
Topics: Actins; Animals; Apoptosis; Cadherins; Cyclosporine; Drug Evaluation, Preclinical; Extracellular Signal-Regulated MAP Kinases; Fluorobenzenes; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunosuppressive Agents; JNK Mitogen-Activated Protein Kinases; Kidney; Kidney Diseases; Male; MAP Kinase Signaling System; Nitric Oxide Synthase Type II; Proteins; Pyrimidines; Rats; Rats, Sprague-Dawley; Rosuvastatin Calcium; Smad Proteins; Sulfonamides; Transforming Growth Factor beta1 | 2013 |
Angiotensin II regulation of vascular endothelial growth factor and receptors Flt-1 and KDR/Flk-1 in cyclosporine nephrotoxicity.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Cyclosporine; Disease Models, Animal; Enalapril; Endothelial Growth Factors; Extracellular Matrix Proteins; Gene Expression; Immunosuppressive Agents; Intercellular Signaling Peptides and Proteins; Kidney Diseases; Losartan; Lymphokines; Male; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2; Vascular Endothelial Growth Factors | 2002 |
Renal dysfunction in allogeneic hematopoietic cell transplantation.
Topics: Adult; Cyclosporine; Female; Glomerular Filtration Rate; Hematocrit; Hematopoietic Stem Cell Transplantation; Hemoglobins; Humans; Immunosuppressive Agents; Kidney Diseases; Liver Diseases; Male; Middle Aged; Pancytopenia; Platelet Count; Retrospective Studies; Risk Factors; Transplantation, Homologous | 2002 |
Expression of apoptosis-related genes in chronic cyclosporine nephrotoxicity in mice.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blood Pressure; Body Weight; Caspase 1; Caspase 3; Caspases; Chronic Disease; Cyclosporine; Fas Ligand Protein; fas Receptor; Immunohistochemistry; Immunosuppressive Agents; Kidney Diseases; Male; Membrane Glycoproteins; Mice; Mice, Inbred ICR; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tumor Suppressor Protein p53 | 2002 |
Selective angiotensin II type 1 receptor blockade ameliorates cyclosporine nephrotoxicity.
Topics: Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood Urea Nitrogen; Body Weight; Creatine; Creatinine; Cyclosporine; Drinking; Female; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Function Tests; Lipid Peroxidation; Lipid Peroxides; Male; Oxidative Stress; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Tetrazoles; Urodynamics | 2002 |
Protective effect of L-arginine against nephrotoxicity induced by cyclosporine in normal rats.
Topics: Animals; Arginine; Creatinine; Cyclosporine; Enzyme Inhibitors; Glutathione Peroxidase; Guanidines; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Tubules; Male; Nephritis, Interstitial; Nitric Oxide Synthase; Rats; Rats, Inbred Strains; Urea | 2002 |
Oxidative stress-mediated renal dysfunction by cyclosporine A in rats: attenuation by trimetazidine.
Topics: Animals; Biomarkers; Blood Pressure; Blood Urea Nitrogen; Body Weight; Creatinine; Cyclosporine; Disease Models, Animal; Drinking; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Immunosuppressive Agents; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Oxidative Stress; Rats; Rats, Wistar; Systole; Thiobarbituric Acid Reactive Substances; Time Factors; Treatment Outcome; Trimetazidine; Vasodilator Agents | 2002 |
Cyclosporin withdrawal with concomitant conversion from azathioprine to mycophenolate mofetil in renal transplant recipients with chronic allograft nephropathy: a 2-year follow-up.
Topics: Adult; Aged; Azathioprine; Chronic Disease; Cyclosporine; Female; Follow-Up Studies; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Mycophenolic Acid; Transplantation, Homologous | 2002 |
Reversal of chronic cyclosporine nephrotoxicity after heart transplantation-potential role of mycophenolate mofetil.
Topics: Azathioprine; Chronic Disease; Cyclosporine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Heart Transplantation; Humans; Immunosuppressive Agents; Kidney Diseases; Male; Middle Aged; Mycophenolic Acid; Remission Induction; Treatment Outcome | 2002 |
Long-term comparison of tacrolimus- and cyclosporine-induced nephrotoxicity in pediatric heart-transplant recipients.
Topics: Child; Cyclosporine; Female; Heart Transplantation; Humans; Immunosuppressive Agents; Kidney Diseases; Male; Retrospective Studies; Tacrolimus; Time Factors | 2002 |
Nephrotoxicity of cyclosporine A and amphotericin B-deoxycholate as continuous infusion in allogenic stem cell transplantation.
Topics: Adult; Amphotericin B; Cyclosporine; Deoxycholic Acid; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Female; Humans; Infusion Pumps; Kidney Diseases; Male; Stem Cell Transplantation | 2002 |
Salvage of cyclosporine A-induced oxidative stress and renal dysfunction by carvedilol.
Topics: Animals; Antioxidants; Blood Pressure; Body Weight; Carbazoles; Carvedilol; Cyclosporine; Disease Models, Animal; Drinking; Female; Immunosuppressive Agents; Kidney Diseases; Lipid Peroxidation; Male; Oxidative Stress; Propanolamines; Rats; Rats, Wistar; Urine | 2002 |
Endothelin-1 in the kidney and urine of patients with glomerular disease and proteinuria.
Topics: Adult; Anti-Inflammatory Agents; Cyclosporine; Endothelin-1; Female; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Glomerulus; Male; Middle Aged; Prednisolone; Proteinuria; Remission Induction; Severity of Illness Index | 2002 |
Expression of TGF-beta and fibrogenic genes in transplant recipients with tacrolimus and cyclosporine nephrotoxicity.
Topics: Biopsy; Collagen; Cyclosporine; Fibronectins; Gene Expression; Graft Rejection; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Matrix Metalloproteinase 9; Osteopontin; RNA, Messenger; Sialoglycoproteins; Tacrolimus; Tissue Inhibitor of Metalloproteinase-2; Transforming Growth Factor beta | 2002 |
Transforming growth factor-beta(1) in the kidney and urine of patients with glomerular disease and proteinuria.
Topics: Adult; Aged; Cyclosporine; Female; Glucocorticoids; Humans; Immunohistochemistry; Immunosuppressive Agents; In Situ Hybridization; Kidney Diseases; Kidney Glomerulus; Male; Middle Aged; Nephrotic Syndrome; Osmolar Concentration; Prednisolone; Proteinuria; Remission Induction; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2002 |
EVE/cyclosporin (etoposide, vincristine, epirubicin with high-dose cyclosporin)-chemotherapy selected for multidrug resistance modulation.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclosporine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Epirubicin; Etoposide; Female; Gastrointestinal Diseases; Heart Diseases; Hematologic Diseases; Humans; Kidney Diseases; Male; Neoplasms; Vincristine | 2002 |
Differential diagnosis of kidney transplant rejection and cyclosporin/tacrolimus nephropathy using urine cytology.
Topics: Adolescent; Adult; Aged; Child; Cyclosporine; Cytological Techniques; Diagnosis, Differential; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Leukocytes, Mononuclear; Middle Aged; Tacrolimus | 2002 |
Therapeutic benefit of spironolactone in experimental chronic cyclosporine A nephrotoxicity.
Topics: Aldosterone; Animals; Chronic Disease; Collagen Type I; Collagen Type IV; Cyclosporine; Fibronectins; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Mineralocorticoid Receptor Antagonists; Rats; Rats, Wistar; RNA, Messenger; Spironolactone; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2003 |
Basiliximab-sirolimus-prednisone induction regimen followed by delayed low-dose cyclosporine in renal transplant recipients of living donors.
Topics: Adult; Antibodies, Monoclonal; Basiliximab; Cholesterol; Creatinine; Cyclosporine; Drug Therapy, Combination; Ethnicity; Female; Histocompatibility Testing; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Living Donors; Male; Prednisone; Recombinant Fusion Proteins; Retrospective Studies; Sirolimus; Texas | 2002 |
Variability of cyclosporine exposure and its relevance to chronic allograft nephropathy: a case-control study.
Topics: Adult; Age Factors; Case-Control Studies; Chronic Disease; Cyclosporine; Female; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Prognosis; Transplantation, Homologous | 2002 |
Reversibility of chronic cyclosporine nephropathy in rats after withdrawal of cyclosporine.
Topics: Animals; Chronic Disease; Cyclosporine; Drug Administration Schedule; Immunosuppressive Agents; Kidney; Kidney Diseases; Macrophages; Male; Osteopontin; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Sialoglycoproteins | 2003 |
Therapeutic role of TGF-beta-neutralizing antibody in mouse cyclosporin A nephropathy: morphologic improvement associated with functional preservation.
Topics: Animals; Antibodies, Monoclonal; Apoptosis; Chronic Disease; Cyclosporine; Extracellular Matrix Proteins; Kidney; Kidney Diseases; Male; Mice; Mice, Inbred ICR; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Transforming Growth Factor beta | 2003 |
Kidney function and morphology after short-term combination therapy with cyclosporine A, tacrolimus and sirolimus in the rat.
Topics: Animals; Cyclosporine; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Glomerulus; Male; Rats; Rats, Sprague-Dawley; Sirolimus; Tacrolimus; Time Factors | 2003 |
Synergistic effects of mycophenolate mofetil and losartan in a model of chronic cyclosporine nephropathy.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Arterioles; Blood Pressure; Body Weight; Chronic Disease; Cyclosporine; Drug Synergism; Fibrosis; Gene Expression; Immunosuppressive Agents; Kidney; Kidney Diseases; Losartan; Macrophages; Male; Mycophenolic Acid; Osteopontin; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sialoglycoproteins; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2003 |
Long-term calcineurin inhibition and magnesium balance after renal transplantation.
Topics: Adolescent; Adult; Aged; Calcineurin Inhibitors; Cyclosporine; Enzyme Inhibitors; Female; Homeostasis; Humans; Kidney Diseases; Kidney Transplantation; Magnesium; Male; Middle Aged; Postoperative Complications | 2003 |
Nitric oxide modulates vascular endothelial growth factor and receptors in chronic cyclosporine nephrotoxicity.
Topics: Animals; Chronic Disease; Cyclosporine; Enzyme Inhibitors; Extracellular Matrix Proteins; Kidney; Kidney Diseases; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2 | 2003 |
Protein-rich diet attenuates cyclosporin A-induced renal tubular damage in rats.
Topics: Acetylglucosaminidase; Animals; beta-Galactosidase; Body Weight; Caseins; Creatinine; Cyclosporine; Diet, Fat-Restricted; Dietary Proteins; Diuresis; Drinking; Energy Intake; Female; gamma-Glutamyltransferase; Immunohistochemistry; Kidney Diseases; Kidney Tubules, Proximal; Rats; Rats, Sprague-Dawley | 2003 |
Neuropsychologic side-effects of tacrolimus in pediatric renal transplantation.
Topics: Abdominal Pain; Adolescent; Aggression; Amenorrhea; Child; Child Behavior Disorders; Cyclosporine; Depression; Diabetes Mellitus; Drug Resistance; Female; Gingival Hyperplasia; Graft Rejection; Humans; Hypertrichosis; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Sleep Initiation and Maintenance Disorders; Tacrolimus; Weight Loss | 2003 |
Chronic allograft nephropathy is prevented by inhibition of platelet-derived growth factor receptor: tyrosine kinase inhibitors as a potential therapy.
Topics: Animals; Benzamides; Chronic Disease; Cyclosporine; Enzyme Inhibitors; Graft Rejection; Imatinib Mesylate; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Male; Piperazines; Protein-Tyrosine Kinases; Pyrimidines; Rats; Rats, Inbred Strains; Rats, Inbred WF; Receptors, Platelet-Derived Growth Factor; Transplantation, Homologous; Transplantation, Isogeneic | 2003 |
Lip hypertrophy secondary to cyclosporin treatment.
Topics: Child; Cyclosporine; Cystinosis; Humans; Hypertrophy; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Lip Diseases; Male | 2003 |
A pilot protocol of a calcineurin-inhibitor free regimen for kidney transplant recipients of marginal donor kidneys or with delayed graft function.
Topics: Adult; Aged; Calcineurin Inhibitors; Clinical Protocols; Cyclosporine; Female; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Mycophenolic Acid; Pilot Projects; Prednisone; Recovery of Function; Sirolimus; Tacrolimus | 2003 |
Graft survival following living-donor renal transplantation: a comparison of tacrolimus and cyclosporine microemulsion with mycophenolate mofetil and steroids.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Child; Child, Preschool; Cyclosporine; Databases, Factual; Drug Therapy, Combination; Female; Follow-Up Studies; Graft Survival; Humans; Immunosuppressive Agents; Infant; Kidney Diseases; Kidney Transplantation; Living Donors; Male; Middle Aged; Mycophenolic Acid; Racial Groups; Registries; Retrospective Studies; Tacrolimus; Time Factors | 2003 |
Early interstitial accumulation of collagen type I discriminates chronic rejection from chronic cyclosporine nephrotoxicity.
Topics: Actins; Adult; Biopsy; Chronic Disease; Collagen Type I; Cyclosporine; Extracellular Matrix; Fibrosis; Graft Rejection; Humans; Image Processing, Computer-Assisted; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Laminin; Middle Aged; Muscle, Smooth; ROC Curve; Time Factors | 2003 |
Urinary transforming growth factor-beta1 excretion in renal allograft recipients during the early post-transplantation period.
Topics: Adult; Biomarkers; Biopsy; Creatinine; Cyclosporine; Female; Follow-Up Studies; Humans; Immunohistochemistry; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Postoperative Period; Renal Dialysis; Statistics as Topic; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Treatment Outcome | 2003 |
Relationship between development of nephrotoxicity and blood concentration of cyclosporine A in bone-marrow transplanted recipients who received the continuous intravenous infusion.
Topics: Adult; Area Under Curve; Bone Marrow Transplantation; Cyclosporine; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Kidney Diseases; Male; Retrospective Studies | 2003 |
The long-term effect of switching from cyclosporin A to mycophenolate mofetil in chronic renal graft dysfunction compared with conventional management.
Topics: Adult; Cardiovascular Abnormalities; Cyclosporine; Female; Graft Survival; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Mycophenolic Acid; Retrospective Studies; Treatment Outcome | 2003 |
Living donor transplantations with marginal kidneys.
Topics: Adult; Age Factors; Aged; Cadaver; Cyclosporine; Female; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Living Donors; Male; Middle Aged; Nephrectomy; Postoperative Complications; Tissue and Organ Harvesting; Tissue Donors; Treatment Outcome | 2003 |
Mycophenolate mofetil in stable liver transplant patients with calcineurin inhibitor-induced renal impairment: single-center experience.
Topics: Adult; Aged; Calcineurin Inhibitors; Cyclosporine; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Kidney Diseases; Liver Diseases; Liver Transplantation; Male; Middle Aged; Mycophenolic Acid; Portugal; Postoperative Complications; Retrospective Studies; Time Factors | 2003 |
Beneficial effects of a diet rich in a mixture of n - 6/n - 3 essential fatty acids and of their metabolites on cyclosporine - nephrotoxicity.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cyclosporine; Dietary Fats, Unsaturated; Dinoprostone; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Female; Kidney; Kidney Diseases; Prostaglandins I; Proteinuria; Rats; Rats, Wistar; Thromboxane B2; Weight Loss | 2003 |
Phosphodiesterase type 5 inhibition ameliorates nephrotoxicity induced by cyclosporin A in spontaneous hypertensive rats.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Aorta; Benzamides; Blood Platelets; Body Weight; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Cyclosporine; Guanylate Cyclase; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Potassium; Rats; Rats, Inbred SHR; Sodium | 2003 |
Inhibitory effect of tea polyphenols on renal cell apoptosis in rat test subjects suffering from cyclosporine-induced chronic nephrotoxicity.
Topics: Animals; Apoptosis; Cyclosporine; Flavonoids; Kidney; Kidney Diseases; Male; Phenols; Polyphenols; Rats; Rats, Sprague-Dawley; Tea | 2003 |
Rapamycin preserves renal function compared with cyclosporine A after ischemia/reperfusion injury.
Topics: Animals; Calcineurin; Cyclosporine; Glomerular Filtration Rate; Immunosuppressive Agents; Ischemia; Kidney; Kidney Diseases; Kidney Transplantation; Male; Nephrectomy; Postoperative Complications; Rats; Rats, Wistar; Reperfusion Injury; Sirolimus; Tissue and Organ Procurement | 2003 |
Factors involved in the development of hypertension induced by a low-protein diet in rats with renal injury.
Topics: Animals; Arginine; Blood Pressure; Cyclosporine; Diet, Protein-Restricted; Dietary Supplements; Hypertension; Kidney; Kidney Diseases; Male; Nitrates; Nitric Oxide; Nitrites; Rats; Rats, Sprague-Dawley; Sucrose | 2004 |
Cholestasis and kidney dysfunction in liver transplant patients reduces cyclosporine metabolite excretion.
Topics: Adult; Aged; Cholestasis; Cyclosporine; Female; Humans; Immunosuppressive Agents; Kidney Diseases; Liver Transplantation; Male; Middle Aged; Postoperative Period; Regression Analysis; Time Factors | 1992 |
Mycophenolate mofetil-induced reversal of glomerular filtration loss in children with chronic allograft nephropathy.
Topics: Child; Chronic Disease; Cyclosporine; Drug Therapy, Combination; Glomerular Filtration Rate; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Mycophenolic Acid | 2003 |
Diabetes mellitus after transplant: relationship to pretransplant glucose metabolism and tacrolimus or cyclosporine A-based therapy.
Topics: Adult; Antihypertensive Agents; Blood Glucose; Creatinine; Cyclosporine; Demography; Diabetes Mellitus; Female; Glucose Tolerance Test; Humans; Immunosuppressive Agents; Insulin Resistance; Kidney Diseases; Kidney Transplantation; Living Donors; Male; Patient Selection; Tacrolimus | 2003 |
Mycophenolate mofetil ameliorates arteriolopathy and decreases transforming growth factor-beta1 in chronic cyclosporine nephrotoxicity.
Topics: Animals; Arteries; Cyclosporine; Extracellular Matrix Proteins; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Mycophenolic Acid; Plasminogen Activator Inhibitor 1; Rats; Transforming Growth Factor beta | 2003 |
Beneficial effects of a diet rich in a mixture of n - 6/n - 3 essential fatty acids and of their metabolites on cyclosporine - nephrotoxicity.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Creatinine; Cyclosporine; Dinoprostone; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Female; Kidney; Kidney Diseases; Prostaglandins I; Rats; Rats, Wistar; Thromboxane B2; Urine; Weight Loss | 2003 |
Inhibitory effect of tea polyphenols on transforming growth factor-beta1 expression in rat with cyclosporine A-induced chronic nephrotoxicity.
Topics: Animals; Antioxidants; Cyclosporine; Flavonoids; Gene Expression; Kidney; Kidney Diseases; Male; Phenols; Polyphenols; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tea; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2004 |
Increased incidence of acute graft-versus-host disease with the continuous infusion of cyclosporine A compared to twice-daily infusion.
Topics: Acute Disease; Adult; Cyclosporine; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Incidence; Infusions, Intravenous; Kidney Diseases; Leukemia; Male; Multivariate Analysis; Retrospective Studies; Risk Factors; Treatment Outcome | 2004 |
Toward calcineurin antagonist minimization.
Topics: Calcineurin Inhibitors; Chronic Disease; Cyclosporine; Dose-Response Relationship, Drug; Humans; Kidney Diseases; Kidney Transplantation; Transplantation, Homologous | 2004 |
Pulse wave analysis to assess vascular compliance changes in stable renal transplant recipients.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Calcineurin; Calcineurin Inhibitors; Cross-Sectional Studies; Cyclosporine; Diastole; Enzyme Inhibitors; Female; Heart Rate; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Pennsylvania; Pulse; Radial Artery; Systole; Tacrolimus; Time Factors; Treatment Outcome; Vascular Resistance | 2004 |
Direct transfer of hepatocyte growth factor gene into kidney suppresses cyclosporin A nephrotoxicity in rats.
Topics: Animals; Cyclosporine; Gene Transfer Techniques; Genetic Therapy; Hepatocyte Growth Factor; Kidney; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley | 2004 |
Chronic allograft nephropathy.
Topics: Biopsy; Calcineurin Inhibitors; Chronic Disease; Cyclosporine; Enzyme Inhibitors; Graft Rejection; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Observer Variation | 2004 |
Expression of apoptosis-related factors in chronic cyclosporine nephrotoxicity after cyclosporine withdrawal.
Topics: Animals; Apoptosis; Cyclosporine; Epidermal Growth Factor; Fas Ligand Protein; Kidney; Kidney Diseases; Male; Membrane Glycoproteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substance Withdrawal Syndrome; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2004 |
Electroporation-mediated HGF gene transfer ameliorated cyclosporine nephrotoxicity.
Topics: Animals; Apoptosis; Caspase 3; Caspases; Cell Division; Cell Line; Cyclosporine; Electroporation; Gene Transfer Techniques; Genetic Therapy; Hepatocyte Growth Factor; Humans; Kidney; Kidney Diseases; Macrophages; Male; Phenotype; Rats; Rats, Sprague-Dawley | 2004 |
Alendronate versus calcitriol for prevention of bone loss after cardiac transplantation.
Topics: Alendronate; Bone Resorption; Calcitriol; Calcium; Cyclosporine; Drug Therapy, Combination; Heart Transplantation; Humans; Immunosuppressive Agents; Kidney Diseases; Vitamin D | 2004 |
Assessment of a new cell culture perfusion apparatus for in vitro chronic toxicity testing. Part 2: toxicological evaluation.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animal Testing Alternatives; Animals; Cell Culture Techniques; Coloring Agents; Cyclosporine; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; gamma-Glutamyltransferase; Humans; Immunosuppressive Agents; Inhibitory Concentration 50; Kidney Diseases; L-Lactate Dehydrogenase; LLC-PK1 Cells; Oxazines; Perfusion; Sodium Dodecyl Sulfate; Surface-Active Agents; Swine; Time Factors; Toxicity Tests, Chronic; Xanthenes | 2004 |
[Calcineurin-inhibitor-free immunosuppression in early renal transplantation].
Topics: Adult; Calcineurin Inhibitors; Comorbidity; Cyclosporine; Drug Therapy, Combination; Fever; Glomerulosclerosis, Focal Segmental; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Mycophenolic Acid; Prednisone; Pyelonephritis; Recurrence; Sirolimus; Ureteral Diseases; Urinary Bladder Fistula; Urinary Fistula | 2004 |
[Idiopathic membranous nephropathy associated with anti-calcineurin toxicity. Prognosis and other immunosuppressive treatments].
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcineurin Inhibitors; Calcium Channel Blockers; Creatinine; Cyclosporine; Drug Therapy, Combination; Glomerulonephritis, Membranous; Humans; Hypercholesterolemia; Hypertension; Hypolipidemic Agents; Immunosuppressive Agents; Kidney Diseases; Lisinopril; Lovastatin; Male; Nephrotic Syndrome; Prednisone; Recurrence; Verapamil | 2004 |
Impact of chronic allograft nephropathy and subsequent modifications of immunosuppressive therapy on late graft outcomes in renal transplantation.
Topics: Adult; Chronic Disease; Creatinine; Cyclosporine; Drug Therapy, Combination; Female; Graft Survival; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Retrospective Studies; Transplantation, Homologous; Treatment Outcome | 2004 |
Bradykinin decreases plasminogen activator inhibitor-1 expression and facilitates matrix degradation in the renal tubulointerstitium under angiotensin-converting enzyme blockade.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Cyclosporine; Extracellular Matrix; Kidney Diseases; Kidney Tubules; Mice; Plasminogen Activator Inhibitor 1 | 2004 |
Antithymocyte globulin induction allows a prolonged delay in the initiation of cyclosporine in heart transplant patients with postoperative renal dysfunction.
Topics: Adrenal Cortex Hormones; Antilymphocyte Serum; Creatinine; Cyclosporine; Drug Administration Schedule; Female; Graft Rejection; Heart Transplantation; Humans; Immunosuppressive Agents; Kidney Diseases; Male; Middle Aged; Mycophenolic Acid; Postoperative Complications; Postoperative Period; Retrospective Studies; Survival Analysis; Time Factors | 2004 |
Enhanced clinical utility of de novo cyclosporine C2 monitoring after lung transplantation.
Topics: Adult; Area Under Curve; Creatinine; Cyclosporine; Drug Monitoring; Female; Graft Rejection; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Kidney Diseases; Lung Transplantation; Male; Middle Aged | 2004 |
Cyclosporine C2 monitoring improves renal dysfunction after lung transplantation.
Topics: Area Under Curve; Cyclosporine; Drug Monitoring; Female; Humans; Immunosuppressive Agents; Kidney Diseases; Lung Transplantation; Male; Middle Aged; Time Factors | 2004 |
Amelioration of cyclosporine nephrotoxicity by irbesartan, A selective AT1 receptor antagonist.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Biphenyl Compounds; Cyclosporine; Immunosuppressive Agents; Irbesartan; Kidney Diseases; Models, Animal; Oxidative Stress; Rats; Rats, Sprague-Dawley; Tetrazoles | 2004 |
Anti-transforming growth factor antibody at low but not high doses limits cyclosporine-mediated nephrotoxicity without altering rat cardiac allograft survival: potential of therapeutic applications.
Topics: Animals; Antibodies, Monoclonal; Collagen; Cyclosporine; Drug Evaluation, Preclinical; Fibronectins; Gene Expression Regulation; Heart Transplantation; Immunosuppressive Agents; Immunotherapy; Kidney; Kidney Diseases; Kidney Function Tests; Matrix Metalloproteinase 1; Rats; Rats, Inbred Lew; Rats, Inbred WF; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-2; Transforming Growth Factor beta; Transplantation, Heterotopic; Transplantation, Homologous | 2004 |
Cyclosporine therapy monitored with abbreviated area under curve in nephrotic syndrome.
Topics: Adolescent; Area Under Curve; Child; Child, Preschool; Cyclosporine; Drug Monitoring; Female; Humans; Immunosuppressive Agents; Kidney Diseases; Male; Nephrotic Syndrome; Retrospective Studies | 2005 |
Simvastatin and L-arginine preserve renal function after ischemia/reperfusion injury.
Topics: Animals; Arginine; Cyclosporine; Drug Therapy, Combination; Glomerular Filtration Rate; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunosuppressive Agents; Kidney Diseases; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Simvastatin | 2005 |
Increased excretion of urinary 20-HETE in rats with cyclosporine-induced nephrotoxicity.
Topics: Animals; Blood Urea Nitrogen; Creatinine; Cyclosporine; Cytochrome P-450 CYP4A; Drug Administration Schedule; Gene Expression; Hydroxyeicosatetraenoic Acids; Injections, Intraperitoneal; Kidney Cortex; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; Time Factors; Urine; Urodynamics | 2005 |
Effect of molsidomine and L-arginine in cyclosporine nephrotoxicity: role of nitric oxide.
Topics: Administration, Oral; Animals; Arginine; Cyclosporine; Dose-Response Relationship, Drug; Drinking; Drug Therapy, Combination; Enzyme Inhibitors; Immunosuppressive Agents; Injections, Subcutaneous; Kidney Diseases; Male; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Oxidative Stress; Rats; Water Supply | 2005 |
ABCB1 genotype of the donor but not of the recipient is a major risk factor for cyclosporine-related nephrotoxicity after renal transplantation.
Topics: Adult; Aged; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Female; Genes, MDR; Genetic Predisposition to Disease; Genotype; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Polymorphism, Genetic; Postoperative Complications; Predictive Value of Tests; Risk Factors; Tissue Donors | 2005 |
Low serum magnesium is associated with decreased graft survival in patients with chronic cyclosporin nephrotoxicity.
Topics: Adult; Case-Control Studies; Chronic Disease; Cyclosporine; Female; Follow-Up Studies; Graft Survival; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Magnesium; Male; Middle Aged; Retrospective Studies; Severity of Illness Index | 2005 |
Limitations of C2 monitoring in renal transplant recipients.
Topics: Adult; Cyclosporine; Dose-Response Relationship, Drug; Drug Monitoring; Female; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Predictive Value of Tests; Time Factors | 2005 |
Diverse effects of natural antioxidants on cyclosporin cytotoxicity in rat renal tubular cells.
Topics: Animals; Antioxidants; Cell Survival; Cells, Cultured; Cyclosporine; Epithelium; Fluoresceins; Glutathione; Kidney Diseases; Kidney Tubules, Proximal; Lipid Peroxides; Phenylethyl Alcohol; Rats; Rats, Inbred WKY; Reactive Oxygen Species; Resveratrol; Stilbenes; Thiobarbituric Acid Reactive Substances; Vitamin E | 2005 |
Cyclosporine induced nephrotoxicity in renal transplant recipients: clinical significance of fractional excretion of sodium, potassium and magnesium.
Topics: Adolescent; Adult; Biomarkers; Child; Creatinine; Cross-Sectional Studies; Cyclosporine; Female; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Magnesium; Male; Middle Aged; Potassium; Prospective Studies; Sodium; Time Factors | 2005 |
Calcineurin inhibitor-induced nephrotoxicity and renal expression of P-glycoprotein.
Topics: Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcineurin Inhibitors; Case-Control Studies; Coloring Agents; Cyclosporine; Female; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Logistic Models; Male; Tacrolimus | 2005 |
Combined effects of losartan and pravastatin on interstitial inflammation and fibrosis in chronic cyclosporine-induced nephropathy.
Topics: Animals; C-Reactive Protein; Cyclosporine; Disease Models, Animal; Fibrosis; Inflammation; Kidney; Kidney Diseases; Losartan; Male; Pravastatin; Rats; Rats, Sprague-Dawley | 2005 |
Effects of STZ-induced diabetes and its treatment with vanadyl sulphate on cyclosporine A-induced nephrotoxicity in rats.
Topics: Animals; Cyclosporine; Diabetes Mellitus, Experimental; Glutathione; Hypoglycemic Agents; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Function Tests; Male; Malondialdehyde; Organ Size; Rats; Rats, Wistar; Vanadium Compounds | 2005 |
Provinol prevents CsA-induced nephrotoxicity by reducing reactive oxygen species, iNOS, and NF-kB expression.
Topics: Animals; Biomarkers; Cyclosporine; Fibrosis; Flavonoids; Immunohistochemistry; Immunosuppressive Agents; Kidney; Kidney Diseases; Lipid Peroxidation; NF-kappa B; Nitric Oxide Synthase Type II; Phenols; Polyphenols; Rats; Rats, Wistar; Reactive Oxygen Species | 2005 |
A prospective longitudinal study of BK virus infection in 104 renal transplant recipients.
Topics: Base Sequence; BK Virus; Cyclosporine; DNA, Viral; Female; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Longitudinal Studies; Male; Middle Aged; Molecular Sequence Data; Polyomavirus Infections; Prospective Studies; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Nucleic Acid; Tacrolimus; Tumor Virus Infections; Viral Load; Virus Replication | 2005 |
Steroids can be safely withdrawn from cyclosporine and mycophenolate mofetil-treated renal allograft recipients: long-term results.
Topics: Adrenal Cortex Hormones; Adult; Cyclosporine; Drug Administration Schedule; Female; Graft Rejection; Histocompatibility Testing; Humans; Isoantibodies; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Mycophenolic Acid; Reoperation; Retrospective Studies | 2005 |
Cyclosporine A-induced renal fibrosis: a role for epithelial-mesenchymal transition.
Topics: Cell Differentiation; Cells, Cultured; Cyclosporine; Dose-Response Relationship, Drug; Epithelial Cells; Fibroblasts; Fibrosis; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Tubules, Proximal; Mesoderm; Muscle, Smooth; Protein Kinase C; Protein Kinase C-alpha; Transforming Growth Factor beta; Up-Regulation | 2005 |
Nifedipine attenuates changes in nitric oxide levels, renal oxidative stress, and nephrotoxicity induced by cyclosporine.
Topics: Analysis of Variance; Animals; Biopsy, Needle; Cyclosporine; Disease Models, Animal; Immunohistochemistry; Kidney Diseases; Kidney Function Tests; Lipid Peroxidation; Male; Nifedipine; Nitric Oxide; Oxidative Stress; Probability; Random Allocation; Rats; Rats, Wistar; Reference Values; Risk Factors; Sensitivity and Specificity | 2005 |
[Expression of matrix metalloproteinase-9 in renal tissues of rats with chronic allograft nephropathy at early stage and the role thereof].
Topics: Animals; Cyclosporine; Host vs Graft Reaction; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Male; Matrix Metalloproteinase 9; Rats; Rats, Inbred F344; Rats, Inbred Lew | 2005 |
Renal dysfunction after heart transplantation: incidence, prognosis and risk factors.
Topics: Adolescent; Adult; Aged; Child; Creatinine; Cyclosporine; Female; Heart Transplantation; Humans; Incidence; Kidney Diseases; Male; Middle Aged; Prognosis; Retrospective Studies; Risk Factors | 2005 |
HEGPOL: randomized, placebo controlled, multicenter, double-blind clinical trial to investigate hepatoprotective effects of glycine in the postoperative phase of liver transplantation [ISRCTN69350312].
Topics: Alanine Transaminase; Aspartate Aminotransferases; Clinical Protocols; Cyclosporine; Cytoprotection; Double-Blind Method; Glycine; Glycine Agents; Kidney Diseases; Kupffer Cells; Liver Transplantation; Multicenter Studies as Topic; Postoperative Care; Randomized Controlled Trials as Topic; Reperfusion Injury; Research Design; Survival Rate | 2005 |
Chronic allograft nephropathy and mycophenolate mofetil introduction in paediatric renal recipients.
Topics: Blood Pressure; Calcineurin Inhibitors; Child; Chronic Disease; Cyclosporine; Female; Glomerular Filtration Rate; Graft Rejection; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Male; Mycophenolic Acid | 2005 |
Independent predictors of renal dysfunction after heart transplantation in patients with normal pretransplant renal function.
Topics: Adult; Age Factors; Aged; Cardiomyopathies; Creatinine; Cyclosporine; Diabetes Complications; Female; Graft Rejection; Heart Transplantation; Humans; Hypertension; Immunosuppressive Agents; Incidence; Kidney Diseases; Logistic Models; Male; Middle Aged; Retrospective Studies; Risk Factors; Sex Factors | 2005 |
Prevention of chronic allograft nephropathy with vitamin D.
Topics: Animals; Blotting, Western; Chronic Disease; Cyclosporine; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Extracellular Matrix; Fibrosis; Graft Rejection; Graft Survival; Immunohistochemistry; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Matrix Metalloproteinases; Rats; Rats, Inbred F344; Rats, Inbred Lew; Rats, Sprague-Dawley; Signal Transduction; Smad7 Protein; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Transplantation, Homologous; Vitamin D | 2005 |
Low calorie commercial sugar is a sensitive marker of glomerular filtration rate.
Topics: Animals; Biomarkers; Cyclosporine; Glomerular Filtration Rate; Immunosuppressive Agents; Inulin; Kidney Diseases; Kidney Function Tests; Male; Rats; Rats, Wistar; Sensitivity and Specificity; Sucrose; Sweetening Agents | 2005 |
Investigating the protective effects of aged garlic extract on cyclosporin-induced nephrotoxicity in rats.
Topics: Administration, Oral; Animals; Blood Urea Nitrogen; Creatinine; Cyclosporine; Drug Evaluation, Preclinical; Eating; Garlic; Kidney; Kidney Diseases; Kidney Function Tests; Male; Phytotherapy; Plant Extracts; Protective Agents; Rats; Rats, Wistar; Urine; Weight Gain | 2005 |
Cyclosporine-induced renal injury induces toll-like receptor and maturation of dendritic cells.
Topics: Animals; Chronic Disease; Cyclosporine; Dendritic Cells; Histocompatibility Antigens Class II; HSP70 Heat-Shock Proteins; Immunosuppressive Agents; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Signal Transduction; Toll-Like Receptor 2; Toll-Like Receptor 4 | 2005 |
Protective effects of heme-oxygenase expression in cyclosporine A--induced injury.
Topics: Animals; Cyclosporine; Down-Regulation; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley | 2005 |
Curcumin, a diferuloylmethane, attenuates cyclosporine-induced renal dysfunction and oxidative stress in rat kidneys.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Curcumin; Cyclosporine; Female; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Function Tests; Male; Oxidative Stress; Rats; Rats, Wistar | 2005 |
Attenuation of ciclosporin-induced nephrotoxicity by dietary supplementation of seal oil in Sprague-Dawley rats.
Topics: 6-Ketoprostaglandin F1 alpha; Acetylglucosaminidase; Animals; Blood Pressure; Blood Urea Nitrogen; Creatinine; Cyclosporine; Dietary Fats, Unsaturated; Fatty Acids; Kidney; Kidney Diseases; Male; Malondialdehyde; Oils; Plant Oils; Rats; Rats, Sprague-Dawley; Seals, Earless; Sunflower Oil; Thromboxane A2; Time Factors | 2005 |
Protective effect of oral L-arginine supplementation on cyclosporine induced nephropathy in rats.
Topics: Animals; Arginine; Atrophy; Cyclosporine; Dietary Supplements; Female; Glomerular Filtration Rate; Immunosuppressive Agents; Kidney Diseases; Kidney Tubules; Necrosis; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley | 2005 |
Acute cyclosporine nephrotoxicity in a patient with oral pemphigus vulgaris and HIV infection on antiretroviral therapy.
Topics: Acute Disease; Adult; Antiretroviral Therapy, Highly Active; Cyclosporine; HIV Infections; Humans; Immunosuppressive Agents; Kidney Diseases; Male; Mouth Diseases; Pemphigus | 2005 |
Effect of FTY720 on chronic cyclosporine nephropathy in rats.
Topics: Angiotensin II; Animals; Chronic Disease; Cyclosporine; Extracellular Matrix Proteins; Fibrosis; Fingolimod Hydrochloride; Immunosuppressive Agents; Kidney; Kidney Diseases; Lymphocytes; Macrophages; Male; Osteopontin; Propylene Glycols; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sialoglycoproteins; Sphingosine; T-Lymphocytes; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Alpha-tocopherol and alpha-lipoic acid enhance the erythrocyte antioxidant defence in cyclosporine A-treated rats.
Topics: alpha-Tocopherol; Animals; Antioxidants; Catalase; Creatinine; Cyclosporine; Dietary Supplements; Erythrocytes; Immunosuppressive Agents; Kidney Diseases; Male; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Thioctic Acid | 2006 |
Investigation of the effect of hyperbaric oxygen on experimental cyclosporine nephrotoxicity.
Topics: Animals; Apoptosis; Cyclosporine; Hyperbaric Oxygenation; Kidney; Kidney Diseases; Male; Necrosis; Rats; Rats, Wistar | 2006 |
Protective effect of L-propionylcarnitine in chronic cyclosporine-a induced nephrotoxicity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Carnitine; Creatinine; Cyclosporine; Immunosuppressive Agents; Kidney Diseases; Lipid Peroxidation; Male; Rats; Rats, Wistar | 2006 |
Taurine attenuates hypertension and renal dysfunction induced by cyclosporine A in rats.
Topics: Animals; Blood Pressure; Body Weight; Catalase; Cyclosporine; Glutathione; Glutathione Peroxidase; Heart Rate; Hypertension; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Function Tests; Male; Nitric Oxide; Rats; Rats, Wistar; Superoxide Dismutase; Taurine; Thiobarbituric Acid Reactive Substances | 2006 |
Kidney transplant function and histological clearance of virus following diagnosis of polyomavirus-associated nephropathy (PVAN).
Topics: Adult; Antiviral Agents; Biopsy; Cidofovir; Cyclosporine; Cytosine; Female; Follow-Up Studies; Humans; Immunosuppression Therapy; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Organophosphonates; Polyomavirus Infections; Postoperative Complications; Treatment Outcome | 2006 |
Lipoic acid supplementation prevents cyclosporine-induced hypertension and nephrotoxicity in spontaneously hypertensive rats.
Topics: Animals; Antioxidants; Blood Pressure; Cyclosporine; Hypertension; Kidney Diseases; Male; Rats; Rats, Inbred SHR; Thioctic Acid | 2006 |
Protective role of polyphenols in cyclosporine A-induced nephrotoxicity during rat pregnancy.
Topics: Animals; Animals, Newborn; Antioxidants; Body Weight; Cyclosporine; Female; Flavonoids; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Glomerulus; Litter Size; Male; Maternal-Fetal Exchange; Matrix Metalloproteinase 2; Morphogenesis; Nitric Oxide Synthase Type II; Phenols; Polyphenols; Pregnancy; Rats; Rats, Wistar | 2006 |
Preliminary experience with mycophenolate mofetil for preservation of renal function in cardiac transplant patients with documented cyclosporine nephrotoxicity.
Topics: Aged; Azathioprine; Chronic Disease; Creatinine; Cyclosporine; Female; Heart Transplantation; Humans; Immunosuppressive Agents; Kidney Diseases; Male; Middle Aged; Mycophenolic Acid; Remission Induction; Treatment Outcome | 2006 |
Independent risk factors for chronic cyclosporine induced nephropathy in children with nephrotic syndrome.
Topics: Adolescent; Child; Child, Preschool; Chronic Disease; Cyclosporine; Female; Humans; Immunosuppressive Agents; Infant; Kidney Diseases; Male; Nephrotic Syndrome; Regression Analysis; Retrospective Studies; Risk Factors | 2006 |
The CARI guidelines. Prevention of progression of kidney disease.
Topics: Acidosis; Adult; Analgesics; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Child; Cyclosporine; Diabetic Nephropathies; Diet, Protein-Restricted; Exercise; Female; Fish Oils; Glomerulonephritis, IGA; Glomerulonephritis, Membranous; Glomerulosclerosis, Focal Segmental; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Hyperuricemia; Kidney Diseases; Kidney Failure, Chronic; Phosphates; Pregnancy; Pregnancy Complications; Proteinuria; Renal Artery Obstruction; Smoking Cessation; Tonsillectomy | 2006 |
Evaluating the effect of sulphated polysaccharides on cyclosporine a induced oxidative renal injury.
Topics: Animals; Antioxidants; Biomarkers; Cyclosporine; Enzymes; Kidney Diseases; Lipid Peroxidation; Male; Oxidative Stress; Polysaccharides; Protective Agents; Rats; Rats, Wistar; Sulfates | 2006 |
[Cyclosporine-induced nephropathy in patients after heart transplantation -- a significant clinical problem].
Topics: Cyclosporine; Heart Transplantation; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Nephrotic Syndrome | 2006 |
Change from cyclosporine to combination therapy of mycophenolic acid with the new sphingosine-1-phosphate receptor agonist, KRP-203, prevents host nephrotoxicity and transplant vasculopathy in rats.
Topics: Animals; Aorta; Aortic Diseases; Arterial Occlusive Diseases; Blood Cell Count; Cyclosporine; Drug Therapy, Combination; Hyperplasia; Immunohistochemistry; Immunosuppressive Agents; Kidney Diseases; Macrophages; Male; Mycophenolic Acid; Rats; Rats, Inbred Strains; Receptors, Lysosphingolipid; Retreatment; Sulfhydryl Compounds; T-Lymphocytes; Transplantation, Homologous; Tunica Intima | 2006 |
Mineralocorticoid receptor blockade confers renoprotection in preexisting chronic cyclosporine nephrotoxicity.
Topics: Animals; Apoptosis; Arterioles; Blood Pressure; Body Weight; Caspase 3; Cell Adhesion Molecules; Cyclosporine; Fibrosis; Immunosuppressive Agents; In Situ Nick-End Labeling; Kidney Diseases; Kidney Glomerulus; Kidney Tubules; Male; Membrane Proteins; Mineralocorticoid Receptor Antagonists; Potassium; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA; Spironolactone; Transforming Growth Factor beta | 2007 |
Excess risk of cancer in renal transplant patients.
Topics: Adult; Cyclosporine; Female; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Neoplasms; Retrospective Studies; Risk; Time Factors | 2006 |
The measurement of whole blood pre-treatment cyclosporine A: metabolite ratios predicts the onset of renal dysfunction in recipients of allogeneic stem cell transplantation.
Topics: Adolescent; Adult; Child; Child, Preschool; Cyclosporine; Drug Monitoring; Female; Fluorescence Polarization Immunoassay; Graft vs Host Disease; Humans; Immunosuppressive Agents; Kidney Diseases; Liver Diseases; Male; Middle Aged; Reproducibility of Results; Stem Cell Transplantation | 2006 |
Reduction of ciclosporin and tacrolimus nephrotoxicity by plant polyphenols.
Topics: Aldehydes; Animals; Camellia sinensis; Chromatography, High Pressure Liquid; Cyclosporine; Flavonoids; Free Radicals; Glomerular Filtration Rate; Glycerol; Immunohistochemistry; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Olive Oil; Phenols; Phytotherapy; Plant Oils; Polyphenols; Rats; Rats, Sprague-Dawley; Tacrolimus | 2006 |
Pioglitazone limits cyclosporine nephrotoxicity in rats.
Topics: Animals; Arterioles; Blood Pressure; Body Weight; Creatinine; Cyclosporine; Drug Interactions; Gene Expression; Hypoglycemic Agents; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Pioglitazone; Plasminogen Activator Inhibitor 1; Rats; Rats, Wistar; RNA, Messenger; Smad3 Protein; Smad7 Protein; Thiazolidinediones; Transforming Growth Factor beta1 | 2006 |
Black grape and garlic extracts protect against cyclosporine a nephrotoxicity.
Topics: Animals; Antioxidants; Cyclosporine; Dietary Supplements; Female; Garlic; Kidney; Kidney Diseases; Plant Extracts; Rats; Rats, Sprague-Dawley; Vitis | 2007 |
Mycophenolate mofetil substitution for cyclosporine-dependent myasthenia gravis and nephrotoxicity.
Topics: Adult; Cyclosporine; Diabetic Nephropathies; Drug Evaluation; Female; Humans; Hypertension, Renal; Immunosuppressive Agents; Kidney Diseases; Kidney Failure, Chronic; Male; Middle Aged; Myasthenia Gravis; Mycophenolic Acid; Plasma Exchange; Prednisolone; Recurrence; Thymectomy | 2007 |
Molecular mechanisms of cyclosporin A inhibition of the cytokine-induced matrix metalloproteinase-9 in glomerular mesangial cells.
Topics: Animals; Cells, Cultured; Cyclosporine; Cytokines; Disease Progression; Enzyme Induction; Glomerular Mesangium; Humans; Immunosuppressive Agents; Interleukin-1beta; Kidney Diseases; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Rats; Recombinant Proteins; Tacrolimus | 2007 |
Beneficial effect of DL-alpha-lipoic acid on cyclosporine A induced hyperlipidemic nephropathy in rats.
Topics: Animals; Antioxidants; Cyclosporine; Humans; Hyperlipidemias; Immunosuppressive Agents; Kidney Diseases; Lipid Metabolism; Lipoproteins; Male; Rats; Rats, Wistar; Thioctic Acid | 2007 |
Mycophenolate mofetil promotes prolonged improvement of renal dysfunction after pediatric liver transplantation: experience of a single center.
Topics: Adolescent; Blood Urea Nitrogen; Child; Child, Preschool; Creatinine; Cyclosporine; Female; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Function Tests; Liver Failure; Liver Transplantation; Male; Mycophenolic Acid; Postoperative Complications; Retrospective Studies; Tacrolimus; Uric Acid; Vaccination | 2007 |
Renal effects of long-term ciclosporin A treatment in a large animal model.
Topics: Administration, Oral; Animals; Cyclosporine; Disease Models, Animal; Drug Evaluation, Preclinical; Kidney; Kidney Diseases; Kidney Function Tests; Longitudinal Studies; Swine; Swine, Miniature | 2007 |
Prevention of chronic cyclosporine nephrotoxicity in Sprague Dawely rats: role of colchicine and omega-3-fatty acids.
Topics: Animals; Colchicine; Cyclosporine; Fatty Acids, Omega-3; Kidney Diseases; Kidney Medulla; Male; Rats; Rats, Sprague-Dawley; Vimentin | 2007 |
A role for HO-1 in renal function impairment in animals subjected to ischemic and reperfusion injury and treated with immunosuppressive drugs.
Topics: Animals; Cyclosporine; Heme Oxygenase-1; Immunosuppressive Agents; Kidney Diseases; Kidney Function Tests; Male; Mice; Mice, Inbred C57BL; Polymerase Chain Reaction; Reperfusion Injury; Sirolimus; Tacrolimus; Transcription, Genetic | 2007 |
Development of biodegradable nanoparticles for oral delivery of ellagic acid and evaluation of their antioxidant efficacy against cyclosporine A-induced nephrotoxicity in rats.
Topics: Administration, Oral; Animals; Antioxidants; Biocompatible Materials; Biological Availability; Cyclosporine; Diffusion; Drug Compounding; Ellagic Acid; Immunosuppressive Agents; Kidney Diseases; Lactic Acid; Male; Microscopy, Polarization; Nanoparticles; Permeability; Polyesters; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Polyvinyl Alcohol; Rats; Rats, Sprague-Dawley; Treatment Outcome | 2007 |
Diabetes mellitus after kidney transplantation: a French multicentre observational study.
Topics: Adult; Blood Glucose; Body Mass Index; Calcineurin Inhibitors; Cyclosporine; Diabetes Mellitus; Emulsions; Fasting; Female; France; Hepatitis C; Humans; Immunosuppressive Agents; Incidence; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Retrospective Studies; Risk Factors; Tacrolimus; Time Factors | 2007 |
Reversal of loss of glomerular filtration rate in children with transplant nephropathy after switch to everolimus and low-dose cyclosporine A.
Topics: Adolescent; Biopsy; Child; Cyclosporine; Drug Therapy, Combination; Everolimus; Female; Glomerular Filtration Rate; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Sirolimus | 2007 |
Induction of PPAR gamma mRNA and protein expression by rosiglitazone in chronic cyclosporine nephropathy in the rat.
Topics: Animals; Cyclosporine; Disease Models, Animal; Gene Expression Regulation; Kidney Diseases; Male; PPAR gamma; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Transcription, Genetic | 2007 |
Intensive observation of toxic side effects after several-year of cyclosporin treatment in kidney transplant patient.
Topics: Adult; Cyclosporine; Dose-Response Relationship, Drug; Female; Graft Rejection; Hemorrhage; Hirsutism; Humans; Hyperlipidemias; Hypertension; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Longitudinal Studies; Male; Middle Aged; Time Factors; Tremor | 2007 |
Effect of hyperbaric oxygen on cyclosporine-induced nephrotoxicity and oxidative stress in rats.
Topics: Animals; Cyclosporine; Drug Synergism; Female; Glutathione Peroxidase; Hyperbaric Oxygenation; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Function Tests; Oxidative Stress; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances | 2007 |
Drug-induced nephrotoxicity in children: pharmacologically based prevention of long-term impairment.
Topics: Amphotericin B; Child; Cyclosporine; Humans; Ifosfamide; Kidney Diseases; Kidney Function Tests; Time Factors | 2007 |
Acid-base status determines cyclosporine-induced hypercalciuria.
Topics: Acid-Base Equilibrium; Animals; Calcium; Cyclosporine; Humans; Hypercalciuria; Immunosuppressive Agents; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley | 2007 |
Sulphated polysaccharides: new insight in the prevention of cyclosporine A-induced glomerular injury.
Topics: Animals; Body Weight; Cyclosporine; Hydrolases; Immunosuppressive Agents; Kidney Diseases; Kidney Glomerulus; Male; Polysaccharides; Rats; Rats, Wistar; Sargassum | 2007 |
Activation of intrarenal complement system in mouse model for chronic cyclosporine nephrotoxicity.
Topics: Animals; CD55 Antigens; Complement C3; Complement C4b; Complement Membrane Attack Complex; Complement System Proteins; Cyclosporine; Disease Models, Animal; Immunity, Innate; Immunoblotting; Immunohistochemistry; Immunosuppressive Agents; Kidney; Kidney Diseases; Leukocyte Common Antigens; Membrane Cofactor Protein; Mice; Microscopy, Confocal; Peptide Fragments | 2007 |
Comparison of the effects of vitamin E and/or quercetin in attenuating chronic cyclosporine A-induced nephrotoxicity in male rats.
Topics: Animals; Antioxidants; Blood Urea Nitrogen; Catalase; Chronic Disease; Creatinine; Cyclosporine; Disease Models, Animal; Drug Therapy, Combination; Glutathione Peroxidase; Kidney; Kidney Diseases; Male; Malondialdehyde; Oxidative Stress; Quercetin; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Vitamin E | 2007 |
Therapeutic efficacy of DL-alpha-lipoic acid on cyclosporine A induced renal alterations.
Topics: Animals; Biomarkers; Cyclosporine; Disease Models, Animal; Enzymes; Kidney; Kidney Diseases; Male; Protective Agents; Rats; Rats, Wistar; Thioctic Acid; Time Factors | 2007 |
Erythropoietin enhances angiogenesis in an experimental cyclosporine A-induced nephrotoxicity model in the rat.
Topics: Angiogenic Proteins; Animals; Cyclosporine; Disease Models, Animal; Erythropoietin; Fibroblast Growth Factor 2; Humans; Kidney; Kidney Diseases; Male; Neovascularization, Physiologic; Rats; Rats, Sprague-Dawley; Recombinant Proteins | 2007 |
Protective effect of lipoic acid on oxidative and peroxidative damage in cyclosporine A-induced renal toxicity.
Topics: Albinism; Animals; Antioxidants; Cyclosporine; Gene Expression Regulation, Enzymologic; Kidney Diseases; Lipid Peroxidation; Male; Nitrates; Nitric Oxide Synthase Type II; Nitrites; Oxidative Stress; Rats; Rats, Wistar; RNA, Messenger; Thioctic Acid | 2007 |
Drug-drug interactions with systemic antifungals in clinical practice.
Topics: Adult; Aged; Amphotericin B; Antifungal Agents; Creatinine; Cyclosporine; Drug Interactions; Female; Fluconazole; France; Furosemide; HIV Infections; Hospitals, University; Humans; Hydrocortisone; Hypokalemia; Intensive Care Units; Itraconazole; Kidney Diseases; Leukemia; Male; Middle Aged; Neoplasms; Retrospective Studies | 2007 |
Beneficial effects of sulfated polysaccharides from Sargassum wightii against mitochondrial alterations induced by Cyclosporine A in rat kidney.
Topics: Animals; Antioxidants; Citric Acid Cycle; Cyclosporine; Electron Transport; Glycosaminoglycans; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Microscopy, Electron, Transmission; Mitochondria; Oxidative Stress; Polysaccharides; Rats; Rats, Wistar; Reactive Oxygen Species; Sargassum; Sulfates | 2007 |
[Prevention of diltiazem in tacrolimus-induced nephrotoxicity: experiment with rats].
Topics: Animals; Creatine; Cyclosporine; Diltiazem; Disease Models, Animal; Dose-Response Relationship, Drug; Kidney; Kidney Diseases; Kidney Transplantation; Male; Postoperative Period; Random Allocation; Rats; Rats, Sprague-Dawley; Tacrolimus | 2007 |
Association of cumulative cyclosporine dose with its irreversible nephrotoxicity in Japanese patients with pediatric-onset autoimmune diseases.
Topics: Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Autoimmune Diseases; Child; Cyclosporine; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Female; Genotype; Half-Life; Humans; Immunosuppressive Agents; Japan; Kidney; Kidney Diseases; Male | 2007 |
Cyclosporine-A-induced nephrotoxicity in children with minimal-change nephrotic syndrome: long-term treatment up to 10 years.
Topics: Child; Child, Preschool; Cyclophosphamide; Cyclosporine; Female; Glomerular Filtration Rate; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Nephrosis, Lipoid | 2008 |
Nigella sativa oil for prevention of chronic cyclosporine nephrotoxicity: an experimental model.
Topics: Animals; Antioxidants; Cyclosporine; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Oxidants; Phytotherapy; Plant Extracts; Plant Oils; Rats; Rats, Wistar | 2008 |
Early renal injury after myeloablative cord blood transplantation in adults.
Topics: Adult; Antineoplastic Agents; Cord Blood Stem Cell Transplantation; Cyclosporine; Female; Hematologic Neoplasms; Humans; Kidney Diseases; Male; Middle Aged; Retrospective Studies; Transplantation Conditioning; Vancomycin; Whole-Body Irradiation | 2008 |
Henoch Schonlein purpura in childhood: clinical analysis of 254 cases over a 3-year period.
Topics: Child; Child, Preschool; Cyclosporine; Female; Follow-Up Studies; Gastrointestinal Diseases; Humans; IgA Vasculitis; Intussusception; Joint Diseases; Kidney Diseases; Male | 2008 |
Beneficial effect of shallot (Allium ascalonicum L.) extract on cyclosporine nephrotoxicity in rats.
Topics: Animals; Body Weight; Creatinine; Cyclosporine; Eating; Glutathione; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Function Tests; Male; Malondialdehyde; Plant Extracts; Rats; Rats, Wistar; Shallots; Sodium; Urodynamics | 2008 |
Sirolimus-based immunosuppression following liver transplantation for hepatocellular carcinoma.
Topics: Adrenal Cortex Hormones; Calcineurin Inhibitors; Carcinoma, Hepatocellular; Cyclosporine; Drug Therapy, Combination; Female; Graft Rejection; Humans; Immunosuppressive Agents; Kaplan-Meier Estimate; Kidney Diseases; Liver Failure; Liver Neoplasms; Liver Transplantation; Male; Middle Aged; Mycophenolic Acid; Neoplasm Recurrence, Local; Proportional Hazards Models; Retrospective Studies; Risk Assessment; Sirolimus; Tacrolimus; Time Factors; Treatment Outcome | 2008 |
Acquired renal cysts after pediatric liver transplantation: association with cyclosporine and renal dysfunction.
Topics: Child; Child, Preschool; Cyclosporine; Female; Glomerular Filtration Rate; Humans; Immunosuppressive Agents; Infant; Kidney Diseases; Kidney Diseases, Cystic; Liver Transplantation; Male; Retrospective Studies; Risk; Time Factors | 2008 |
Prolonged endoplasmic reticulum stress induces apoptotic cell death in an experimental model of chronic cyclosporine nephropathy.
Topics: Animals; Apoptosis; Blotting, Northern; Caspase 12; Cell Death; Cyclosporine; Endoplasmic Reticulum; Immunohistochemistry; In Situ Nick-End Labeling; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; Transcription Factor CHOP | 2008 |
Mycosis fungoides in a lung transplant recipient with advanced ciclosporin nephropathy: management with mechlorethamine and subsequent renal transplantation.
Topics: Administration, Topical; Adult; Antineoplastic Agents; Betamethasone Valerate; Cyclosporine; Humans; Immunocompromised Host; Kidney Diseases; Kidney Transplantation; Lung Transplantation; Male; Mechlorethamine; Mycosis Fungoides; Remission Induction; Skin; Skin Neoplasms | 2008 |
Protective effect of COMP-angiopoietin-1 on cyclosporine-induced renal injury in mice.
Topics: Animals; Blotting, Western; Capillaries; Chemokine CCL2; Cyclosporine; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Immunosuppressive Agents; In Situ Nick-End Labeling; Intercellular Adhesion Molecule-1; Kidney; Kidney Diseases; Kidney Tubules; Mice; Mice, Inbred ICR; Microcirculation; Peptide Fragments; Recombinant Fusion Proteins; Regional Blood Flow; Smad2 Protein; Smad3 Protein; Smad7 Protein | 2008 |
Similar risks for chronic kidney disease in long-term survivors of myeloablative and reduced-intensity allogeneic hematopoietic cell transplantation.
Topics: Adult; Age Factors; Aged; Chronic Disease; Cyclosporine; Female; Follow-Up Studies; Glomerular Filtration Rate; Graft vs Host Disease; Hematologic Diseases; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Incidence; Kidney Diseases; Male; Middle Aged; Myeloablative Agonists; Postoperative Complications; Proportional Hazards Models; Risk; Survivors; Transplantation Conditioning; Transplantation, Homologous; Whole-Body Irradiation | 2008 |
Vascular endothelial growth factor in chronic rat allograft nephropathy.
Topics: Animals; Cyclosporine; Disease Models, Animal; Graft Rejection; Kidney; Kidney Diseases; Kidney Transplantation; Male; Phthalazines; Protein Kinase Inhibitors; Pyridines; Rats; Signal Transduction; Transplantation, Homologous; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2 | 2008 |
Prevention of experimental cyclosporin-induced interstitial fibrosis by losartan and enalapril.
Topics: Animals; Biphenyl Compounds; Blood Pressure; Cyclosporine; Enalapril; Furosemide; Hydralazine; Imidazoles; Kidney; Kidney Diseases; Losartan; Male; Microscopy, Electron, Scanning; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger; Tetrazoles | 1995 |
N-acetyl-beta-D-glucosaminidase enzymuria as an indicator in monitoring the therapy of some rheumatic diseases with potentially nephrotoxic drugs.
Topics: Acetylglucosaminidase; Adolescent; Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Biomarkers; Connective Tissue Diseases; Cyclosporine; Female; Humans; Kidney Diseases; Kidney Tubules, Proximal; Male; Middle Aged; Organogold Compounds; Prednisone; Respiratory Tract Infections; Rheumatic Diseases; Urinary Tract Infections | 1994 |
[alpha 2-macroglobulin in urine. Significance for differential diagnosis of rejection and infections after kidney transplantation].
Topics: Adult; Aged; alpha-Macroglobulins; Bacterial Infections; C-Reactive Protein; Cyclosporine; Cytomegalovirus Infections; Diagnosis, Differential; Female; Graft Rejection; Hematuria; Hemoglobinuria; Humans; Kidney; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Prospective Studies; Sepsis; Urinary Tract Infections | 1994 |
Urinary enzymes as biomarkers of renal injury in experimental nephrotoxicity of immunosuppressive drugs.
Topics: Acetylglucosaminidase; Aminopeptidases; Animals; Biomarkers; CD13 Antigens; Clinical Enzyme Tests; Cyclosporine; Diet, Sodium-Restricted; Glomerular Filtration Rate; Kidney; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; Tacrolimus | 1994 |
Reversal of severe FK506 side effects by conversion to cyclosporine-based immunosuppression.
Topics: Cyclosporine; Dose-Response Relationship, Drug; Gastrointestinal Diseases; Graft Rejection; Humans; Kidney Diseases; Liver Transplantation; Tacrolimus | 1994 |
Adhesion molecule expression (ICAM-1, VCAM-1, E-selectin and PECAM) in human kidney allografts.
Topics: Adolescent; Adult; Aged; Antigens, Differentiation, Myelomonocytic; Cell Adhesion Molecules; Cyclosporine; E-Selectin; Female; Gene Expression Regulation; Glomerulonephritis; Graft Rejection; Humans; Intercellular Adhesion Molecule-1; Kidney Diseases; Kidney Transplantation; Kidney Tubular Necrosis, Acute; Male; Middle Aged; Platelet Endothelial Cell Adhesion Molecule-1; Postoperative Complications; Pyelonephritis; Recurrence; Vascular Cell Adhesion Molecule-1 | 1993 |
Serotonergic measures in cyclosporine A treated rats.
Topics: Animals; Creatinine; Cyclosporine; Hydroxyindoleacetic Acid; Kidney Diseases; Male; Rats; Rats, Wistar; Renal Circulation; Serotonin; Vasoconstriction | 1994 |
Immunosuppression switch in pediatric heart transplant recipients: cyclosporine to FK 506.
Topics: Adolescent; Adult; Antihypertensive Agents; Azathioprine; Cardiac Catheterization; Child; Cyclosporine; Drug Therapy, Combination; Echocardiography; Follow-Up Studies; Graft Rejection; Heart Transplantation; Humans; Hyperlipidemias; Hypertension; Immunosuppression Therapy; Kidney Diseases; Lymphoproliferative Disorders; Prednisone; Tacrolimus; Time Factors | 1995 |
Cyclosporine A induced arteriolopathy in a rat model of chronic cyclosporine nephropathy.
Topics: Animals; Arterioles; Chronic Disease; Cyclosporine; Diet, Sodium-Restricted; Kidney Diseases; Male; Microscopy, Electron; Rats; Rats, Sprague-Dawley; Vascular Diseases | 1995 |
Cellular proliferation and macrophage influx precede interstitial fibrosis in cyclosporine nephrotoxicity.
Topics: Animals; Cell Division; Cell Movement; Cyclosporine; Fibrosis; Kidney; Kidney Diseases; Macrophages; Male; Osteopontin; Rats; Rats, Sprague-Dawley; Renin; Sialoglycoproteins | 1995 |
Cyclosporine neurotoxicity in a renal-transplant recipient.
Topics: Adult; Cyclosporine; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Nephrons | 1995 |
Effect of calcium-channel blocker on tumour necrosis factor alpha (TNF alpha) production in cyclosporin-treated renal transplant recipients.
Topics: Adult; Calcium Channel Blockers; Cyclosporine; Female; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Lymphocytes; Male; Muromonab-CD3; Tumor Necrosis Factor-alpha | 1995 |
Proximal renal tubular acidosis secondary to FK506 in pediatric liver transplant patients.
Topics: Acidosis, Renal Tubular; Administration, Oral; Bicarbonates; Blood Urea Nitrogen; Child; Creatinine; Cyclosporine; Diarrhea, Infantile; Female; Fluid Therapy; Follow-Up Studies; Graft Rejection; Humans; Immunosuppressive Agents; Infant; Kidney Diseases; Kidney Tubules, Proximal; Liver Transplantation; Longitudinal Studies; Prevalence; Tacrolimus | 1995 |
Effect of nifedipine on tubular handling of uric acid in transplanted kidney on cyclosporine A treatment.
Topics: Adolescent; Adult; Child; Creatinine; Cyclosporine; Delayed-Action Preparations; Drug Therapy, Combination; Female; Humans; Ion Transport; Kidney Diseases; Kidney Transplantation; Kidney Tubules; Male; Nifedipine; Probenecid; Uric Acid | 1995 |
[Morbidity of percutaneous biopsy of kidney transplants (Vim-Silverman and Tru-cut needles)].
Topics: Adolescent; Adult; Aged; Anuria; Arteriovenous Fistula; Biopsy, Needle; Creatinine; Cyclosporine; Equipment Design; Female; Follow-Up Studies; Graft Rejection; Hemoperitoneum; Humans; Kidney Diseases; Kidney Glomerulus; Kidney Transplantation; Kidney Tubular Necrosis, Acute; Male; Middle Aged; Proteinuria; Ultrasonography | 1995 |
Prostanoids and cyclosporin-mediated nephrotoxicity in rats: a critical appraisal.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Creatinine; Cyclosporine; Eicosanoids; Kidney; Kidney Diseases; Male; Olive Oil; Plant Oils; Prednisolone; Rats; Rats, Inbred Lew; Thromboxane B2 | 1995 |
Renal transplantation--salvage surgery and suppression.
Topics: Cyclosporine; Graft Rejection; Humans; Immunosuppression Therapy; Intraoperative Complications; Kidney Diseases; Kidney Transplantation; Renal Veins | 1995 |
Lipid peroxidation accompanies cyclosporine nephrotoxicity: effects of vitamin E.
Topics: Animals; Cyclosporine; Glomerular Filtration Rate; Injections, Intraperitoneal; Kidney Diseases; Lipid Peroxidation; Male; Rats; Rats, Sprague-Dawley; Renal Circulation; Selenium; Vitamin E | 1995 |
The magnetic resonance renogram in renal transplant evaluation using dynamic contrast-enhanced MR imaging.
Topics: Adult; Biopsy; Contrast Media; Cyclosporine; Female; Gadolinium; Gadolinium DTPA; Graft Rejection; Humans; Kidney Diseases; Kidney Transplantation; Magnetic Resonance Imaging; Male; Organometallic Compounds; Pentetic Acid; Radioisotope Renography; Transplantation, Homologous | 1995 |
Renal structure and function effects after low dose cyclosporine in psoriasis patients: a preliminary report.
Topics: Adult; Biopsy; Cyclosporine; Female; Glomerular Filtration Rate; Humans; Kidney Diseases; Male; Prospective Studies; Psoriasis | 1995 |
Impaired renal function but not high cyclosporine levels determines increased endothelin plasma levels after heart transplantation.
Topics: Adult; Aged; Cyclosporine; Endothelins; Female; Heart Failure; Heart Transplantation; Humans; Kidney Diseases; Male; Middle Aged | 1995 |
Effects of cyclosporin on kidney glutathione metabolism and cytochrome P-450 in the rabbit: possible implication of eicosanoid metabolism.
Topics: Animals; Cyclosporine; Cytochrome P-450 Enzyme System; Eicosanoids; Female; Glutathione; Kidney Diseases; Rabbits | 1994 |
Effects of cyclosporin A withdrawal on renal function and renal stimulation in liver transplant patients treated with triple-drug immunosuppression for over 2 years.
Topics: Adult; Cyclosporine; Female; Glomerular Filtration Rate; Graft Rejection; Humans; Immunosuppression Therapy; Kidney Diseases; Liver Transplantation; Male; Middle Aged; Prospective Studies; Renal Plasma Flow, Effective | 1994 |
Urinary protein excretion and the diagnosis of graft rejection or renal dysfunction in renal transplant patients.
Topics: Adult; Aged; Cyclosporine; Electrophoresis, Agar Gel; Female; Graft Rejection; Humans; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Proteinuria | 1993 |
Protection against cyclosporin-induced nephrotoxicity: 1. Effect of a PAF antagonist, BN50726.
Topics: Animals; Azepines; Creatinine; Cyclosporine; Drug Interactions; Glutathione; Kidney Cortex; Kidney Diseases; Male; Platelet Activating Factor; Rats; Rats, Sprague-Dawley; Thienopyridines; Urea | 1994 |
Cyclosporine nephrotoxicity: attenuation by an antioxidant-inhibitor of lipid peroxidation in vitro and in vivo.
Topics: Animals; Antioxidants; Cell Line; Cross-Over Studies; Cyclosporine; Epithelium; Glomerular Filtration Rate; Kidney Diseases; Kidney Tubules; Lipid Peroxides; Male; Rats | 1994 |
Cyclosporine monotherapy in children: long-term effect.
Topics: Adolescent; Adult; Age Factors; Biopsy, Needle; Child; Child, Preschool; Creatinine; Cyclosporine; Follow-Up Studies; Graft Rejection; Growth; Growth Hormone; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Retrospective Studies; Time Factors; Tissue Donors | 1994 |
Long-term side effects of cyclosporine-based immunosuppression in patients after liver transplantation.
Topics: Adolescent; Adult; Cyclosporine; Diabetes Mellitus; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Follow-Up Studies; Humans; Hypertension; Immunosuppression Therapy; Kidney; Kidney Diseases; Liver Transplantation; Prevalence; Retrospective Studies; Time Factors | 1994 |
Following an initial decline, glomerular filtration rate stabilizes in heart transplant patients on chronic cyclosporine.
Topics: Adult; Blood Pressure; Cyclosporine; Female; Follow-Up Studies; Glomerular Filtration Rate; Heart Transplantation; Humans; Kidney Diseases; Male; Middle Aged; Renal Plasma Flow; Time Factors | 1994 |
Deleterious effect of cyclosporins on the ischemic kidney in the rat and the protection by the calcium antagonist verapamil.
Topics: Animals; Creatinine; Cyclosporine; Cyclosporins; Ischemia; Kidney; Kidney Diseases; Male; Nephrectomy; Rats; Rats, Sprague-Dawley; Renal Circulation; Verapamil | 1994 |
Plasma levels of tumor necrosis factor (TNF) and soluble TNF receptors in kidney transplant recipients.
Topics: Adult; Aged; Creatinine; Cyclosporine; Female; Graft Rejection; Humans; Immunoassay; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Receptors, Tumor Necrosis Factor; Retrospective Studies; Tumor Necrosis Factor-alpha | 1994 |
Renal function and histopathologic changes in children after liver transplantation.
Topics: Adolescent; Biopsy; Child; Child, Preschool; Chromium Radioisotopes; Cyclosporine; Dose-Response Relationship, Drug; Edetic Acid; Follow-Up Studies; Glomerular Filtration Rate; Glucose; Humans; Immunosuppression Therapy; Infant; Kidney; Kidney Diseases; Lithium; Liver Transplantation; Magnesium; Metabolic Clearance Rate; Osmolar Concentration; p-Aminohippuric Acid; Postoperative Care; Potassium; Preoperative Care; Prospective Studies; Renal Circulation; Severity of Illness Index; Sodium; Time Factors; Uric Acid | 1994 |
Role of nitric oxide in renal hemodynamic abnormalities of cyclosporin nephrotoxicity.
Topics: Animals; Arginine; Blood Pressure; Cyclosporine; Glomerular Filtration Rate; Hemodynamics; Kidney Diseases; Male; Nephrectomy; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Renal Circulation; Vasoconstriction | 1994 |
Measurement of the ratio of glomerular filtration rate to plasma volume from the technetium-99m diethylene triamine pentaacetic acid renogram: comparison with glomerular filtration rate in relation to extracellular fluid volume.
Topics: Adolescent; Adult; Aged; Child; Cyclosporine; Dermatomyositis; Extracellular Space; Glomerular Filtration Rate; Humans; Kidney Diseases; Middle Aged; Plasma Volume; Radioisotope Renography; Retrospective Studies; Technetium Tc 99m Pentetate | 1994 |
[Pulsed Doppler ultrasonography in the month following renal transplantation].
Topics: Acute Disease; Child; Cohort Studies; Cyclosporine; Female; Graft Rejection; Humans; Kidney Diseases; Kidney Transplantation; Kidney Tubular Necrosis, Acute; Male; Postoperative Period; Prospective Studies; Renal Artery; Ultrasonography | 1993 |
Down-modulation of serum erythropoietin levels following cyclosporin A infusion.
Topics: Bone Marrow Transplantation; Cyclosporine; Depression, Chemical; Erythropoietin; Humans; Infusions, Intravenous; Kidney Diseases; Kidney Function Tests; Prospective Studies; Secretory Rate | 1994 |
[Basic studies on the prevention of cyclosporin A induced nephrotoxicity].
Topics: Animals; Cyclosporine; Diltiazem; Humans; Kidney; Kidney Diseases; Lymphocyte Activation; Male; Rats; Rats, Wistar; Theophylline | 1994 |
Long-term cyclosporin A nephrotoxicity in the rat. Evaluation of a morphological scoring system and of co-treatment with isradipine.
Topics: Animals; Cyclosporine; Isradipine; Kidney Diseases; Male; Prospective Studies; Rats; Rats, Sprague-Dawley; Time Factors | 1994 |
Reversibility of impaired renal function after long-term cyclosporin for psoriasis.
Topics: Adolescent; Adult; Aged; Cyclosporine; Female; Humans; Kidney; Kidney Diseases; Male; Middle Aged; Psoriasis; Time Factors | 1994 |
[Treatment of refractory rheumatoid arthritis with cyclosporine].
Topics: Administration, Oral; Adult; Aged; Arthritis, Rheumatoid; Cyclosporine; Drug Evaluation; Drug Resistance, Microbial; Female; Humans; Hypertension; Kidney Diseases; Male; Middle Aged; Prospective Studies | 1994 |
Pregnancy outcome in renal allograft recipients in Norway. The importance of immunosuppressive drug regimen and health status before pregnancy.
Topics: Abortion, Induced; Abortion, Spontaneous; Adult; Counseling; Cyclosporine; Female; Graft Rejection; Health Status; Health Surveys; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Norway; Obstetric Labor, Premature; Parity; Pregnancy; Pregnancy Complications; Pregnancy Outcome | 1994 |
Cyclosporine A nephrotoxicity.
Topics: Acute Disease; Chronic Disease; Cyclosporine; Humans; Kidney Diseases | 1994 |
Effects of BQ-123 on renal function and acute cyclosporine-induced renal dysfunction.
Topics: Animals; Blood Pressure; Cyclosporine; Endothelin Receptor Antagonists; Kidney; Kidney Diseases; Kidney Function Tests; Male; Peptides, Cyclic; Pharmaceutical Vehicles; Polyethylene Glycols; Rats; Rats, Inbred Strains; Reference Values | 1994 |
Cyclosporin A nephropathy: standardization of the evaluation of kidney biopsies.
Topics: Adolescent; Adult; Atrophy; Autoimmune Diseases; Biopsy; Child; Cyclosporine; Female; Fibrosis; Glomerulosclerosis, Focal Segmental; Humans; Kidney; Kidney Diseases; Kidney Glomerulus; Kidney Tubules; Male; Middle Aged; Reproducibility of Results | 1994 |
Effect of nephrotoxic drugs on the development of radiation nephropathy after bone marrow transplantation.
Topics: Amphotericin B; Animals; Bone Marrow Transplantation; Busulfan; Cyclosporine; Gentamicins; Kidney; Kidney Diseases; Male; Rats; Whole-Body Irradiation | 1994 |
Chronic cyclosporine-induced nephrotoxicity: a rabbit model.
Topics: Animals; Blood Pressure; Creatinine; Cyclosporine; Disease Models, Animal; Germ-Free Life; Glomerular Filtration Rate; Immune Tolerance; Kidney; Kidney Diseases; Rabbits; Regional Blood Flow; Weight Loss | 1994 |
The increased efficacy and decreased nephrotoxicity of a cyclosporine liposome.
Topics: Animals; Cyclosporine; Female; Graft Rejection; Kidney Diseases; Liposomes; Liver Transplantation; Male; Models, Biological; Rats; Rats, Inbred Lew; Transplantation, Homologous | 1994 |
Comparison of adrenal functions in kidney transplant recipients with different long-term immunosuppressive treatments--prednisolone and azathioprine versus prednisolone and cyclosporine.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Adult; Azathioprine; Cyclosporine; Dose-Response Relationship, Drug; Endocrine Glands; Female; Humans; Hydrocortisone; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Osteoporosis; Pneumonia; Prednisolone | 1993 |
Expression of adhesion molecules in allograft renal dysfunction. A distinct diagnostic pattern in rejection and cyclosporine nephrotoxicity.
Topics: Adult; Cadaver; Cell Adhesion Molecules; Cyclosporine; Female; Graft Rejection; Humans; Kidney; Kidney Diseases; Kidney Transplantation; Leukocytes; Male; Middle Aged; Transplantation, Homologous | 1993 |
Renal hypoperfusion as the primary cause of cyclosporin-induced nephropathy.
Topics: Cyclosporine; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Humans; Kidney Diseases; Renal Circulation; Vasoconstriction | 1993 |
Alleviation of experimental cyclosporin A nephrotoxicity by low dose aspirin in the rat.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Aspirin; Creatinine; Cyclosporine; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; Thromboxane A2; Urea | 1993 |
Cyclosporine-induced nephrotoxicity in deoxycorticosterone-NaCl treated rats.
Topics: Animals; Cyclosporine; Desoxycorticosterone; Hypertension; Kidney; Kidney Cortex; Kidney Diseases; Kidney Transplantation; Male; Microscopy, Electron; Rats; Rats, Sprague-Dawley; Sodium Chloride | 1993 |
The effect of prostaglandin E1 analog misoprostol on chronic cyclosporin nephrotoxicity.
Topics: Aldosterone; Animals; Atrial Natriuretic Factor; Blood Pressure; Chronic Disease; Creatinine; Cyclosporine; Drug Therapy, Combination; Electrolytes; Glomerular Filtration Rate; Heart Rate; Hypertension; Kidney Diseases; Misoprostol; Osmolar Concentration; Prostaglandins; Rats; Rats, Sprague-Dawley; Renal Circulation; Renin | 1993 |
Low-dose cyclosporin nephrotoxicity in the rat.
Topics: Animals; Blood Pressure; Cyclosporine; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; Renal Circulation | 1993 |
Hormonal and other mechanisms involved in the pathogenesis of cyclosporin-induced nephrotoxicity and hypertension in man.
Topics: Angiotensins; Cyclosporine; History, 20th Century; Humans; Hypertension; Kidney; Kidney Diseases; Organ Transplantation; Prostaglandins; Renin-Angiotensin System | 1994 |
Renal biopsy specimens from patients with rheumatoid arthritis and apparently normal renal function after therapy with cyclosporine. Canadian Multicentre Rheumatology Group.
Topics: Adult; Aged; Arthritis, Rheumatoid; Biopsy; Cyclosporine; Female; Humans; Kidney; Kidney Diseases; Male; Middle Aged | 1994 |
An in vitro model of cyclosporine-induced nephrotoxicity.
Topics: Alkaline Phosphatase; Animals; Cell Survival; Cells, Cultured; Cyclosporine; Fluoresceins; Fluorescent Dyes; Kidney Cortex; Kidney Diseases; L-Lactate Dehydrogenase; Mitochondria; Neutral Red; Pharmaceutical Vehicles; Polyethylene Glycols; Propidium; Rats; Rats, Sprague-Dawley; Tetrazolium Salts; Thiazoles | 1993 |
[99mTc-DTPA scintigraphy in renal transplantation. Limitations related to the immunosuppressor used].
Topics: Azathioprine; Cyclosporine; Graft Rejection; Humans; Kidney Diseases; Kidney Transplantation; Kidney Tubular Necrosis, Acute; Postoperative Complications; Radionuclide Imaging; Renal Circulation; Retrospective Studies; Sensitivity and Specificity; Steroids; Technetium Tc 99m Pentetate | 1993 |
Clinical correlations of cyclosporine-specific and -nonspecific assays in stable renal transplants, acute rejection, and cyclosporine nephrotoxicity.
Topics: Acute Disease; Adolescent; Adult; Aged; Child; Chromatography, High Pressure Liquid; Cyclosporine; Dose-Response Relationship, Drug; Female; Fluorescence Polarization Immunoassay; Graft Rejection; Humans; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Sensitivity and Specificity | 1993 |
Chronic cyclosporin A (CsA) nephrotoxicity in the rat: the effect of calcium blockade with verapamil.
Topics: Animals; Blood Glucose; Body Weight; Cyclosporine; Kidney; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; Verapamil | 1993 |
Nonoperative management of post-transplantation bladder leak: serendipitous salutary effect of temporary cyclosporine nephrotoxicity and oligoanuria.
Topics: Adult; Anuria; Cyclosporine; Humans; Kidney Diseases; Kidney Transplantation; Male; Postoperative Complications; Urinary Bladder Fistula | 1993 |
Dissolving intravenous cyclosporin A in a fat emulsion carrier prevents acute renal side effects in the rat.
Topics: Animals; Cyclosporine; Drug Carriers; Emulsions; Glomerular Filtration Rate; Glycerol; Infusions, Intravenous; Kidney; Kidney Diseases; Male; Rats; Rats, Wistar; Solubility; Soybean Oil | 1993 |
Renal function and biopsy findings after 5 years' treatment with low-dose cyclosporin for psoriasis.
Topics: Adult; Creatinine; Cyclosporine; Female; Glomerular Filtration Rate; Humans; Hypertension, Renal; Kidney; Kidney Diseases; Long-Term Care; Male; Middle Aged; Psoriasis | 1993 |
The reversal of experimental cyclosporin A nephrotoxicity by thromboxane synthetase inhibition.
Topics: Animals; Body Weight; Cyclosporine; Enzyme Inhibitors; Kidney Diseases; Male; Prostaglandins; Pyridines; Rats; Rats, Sprague-Dawley; Thromboxane B2; Thromboxane-A Synthase | 1993 |
Potentiation of cyclosporine nephrotoxicity by nafcillin in lung transplant recipients.
Topics: Adolescent; Adult; Aged; Child; Cyclosporine; Drug Synergism; Female; Follow-Up Studies; Humans; Kidney; Kidney Diseases; Lung Transplantation; Male; Middle Aged; Nafcillin | 1993 |
15 AU81, a prostacyclin analog, potentiates immunosuppression and mitigates renal injury due to cyclosporine.
Topics: Animals; Cyclosporine; Drug Synergism; Graft Survival; Immune Tolerance; Kidney Diseases; Kidney Transplantation; Models, Biological; Prostaglandins, Synthetic; Rabbits | 1993 |
Production of less chronic nephrotoxicity by cyclosporine G than cyclosporine A in a low-salt rat model.
Topics: Animals; Cyclosporine; Cyclosporins; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Nephritis, Interstitial; Rats; Rats, Sprague-Dawley | 1993 |
Clinically silent progressive renal tubulointerstitial disease during cisplatin chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Creatinine; Cyclosporine; Cystadenocarcinoma; Female; Humans; Injections, Intraperitoneal; Injections, Intravenous; Kidney Diseases; Kidney Failure, Chronic; Kidney Tubular Necrosis, Acute; Kidney Tubules; Middle Aged; Ovarian Neoplasms | 1993 |
Incidence of adverse reactions to cyclosporine after liver transplantation is predicted by the first blood level.
Topics: Adolescent; Adult; Aged; Cyclosporine; Female; Graft Rejection; Humans; Immunosuppression Therapy; Kidney Diseases; Liver Transplantation; Male; Middle Aged; Nervous System Diseases | 1993 |
The fractional excretion of urea: a new diagnostic test for acute renal allograft rejection.
Topics: Acute Disease; Adolescent; Adult; Bacterial Infections; Child; Child, Preschool; Cyclosporine; Diagnosis, Differential; Graft Rejection; Humans; Kidney Diseases; Kidney Transplantation; Sodium; Transplantation, Homologous; Urea; Virus Diseases | 1993 |
Cyclosporine dosing.
Topics: Cyclosporine; Humans; Immunosuppressive Agents; Kidney Diseases | 1995 |
Absorption of a new oral formulation of cyclosporin A in a child on parenteral nutrition.
Topics: Administration, Oral; Child, Preschool; Cyclosporine; Humans; Immunosuppressive Agents; Intestinal Absorption; Kidney Diseases; Kidney Transplantation; Male; Parenteral Nutrition, Total; Protein-Losing Enteropathies | 1995 |
Pathogenesis of cyclosporine nephropathy: roles of angiotensin II and osteopontin.
Topics: Angiotensin II; Animals; Blood Pressure; Cyclosporine; Cytokines; Immunohistochemistry; Kidney; Kidney Diseases; Male; Osteopontin; Rats; Rats, Sprague-Dawley; Sialoglycoproteins | 1995 |
Clinically relevant doses and blood levels produce experimental cyclosporine nephrotoxicity when combined with nitric oxide inhibition.
Topics: Animals; Arginine; Body Weight; Cyclosporine; Diet, Sodium-Restricted; Enzyme Inhibitors; Hemodynamics; Kidney Cortex; Kidney Diseases; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 1996 |
Comparison of kidney graft survival in Asian and Caucasian patients transplanted in the United States.
Topics: Adolescent; Adult; Age Factors; Asia; Cyclosporine; Cytomegalovirus Infections; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Female; Graft Survival; Histocompatibility Testing; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Organ Preservation; Regression Analysis; Risk Factors; Sex Factors; Survival Rate; Tissue Donors; United States; White People | 1996 |
Role of transforming growth factor-beta 1 in experimental chronic cyclosporine nephropathy.
Topics: Animals; Body Weight; Chronic Disease; Creatinine; Cyclosporine; Disease Models, Animal; Extracellular Matrix Proteins; Fibrosis; Fluorescent Antibody Technique; Gene Expression; Kidney Cortex; Kidney Diseases; Kidney Medulla; Male; Plasminogen Activator Inhibitor 1; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium; Transforming Growth Factor beta | 1996 |
Role of endothelin in renal function and dysfunction.
Topics: Acute Kidney Injury; Animals; Contrast Media; Cyclosporine; Endothelins; Ischemia; Kidney; Kidney Diseases; Rats; Renal Circulation; Vasoconstriction | 1996 |
Experience of FK506 immune suppression in pediatric heart transplantation: a study of long-term adverse effects.
Topics: Anemia; Case-Control Studies; Child; Cyclosporine; Drug Hypersensitivity; Female; Follow-Up Studies; Gastrointestinal Diseases; Graft Rejection; Heart Transplantation; Humans; Hyperkalemia; Immunosuppressive Agents; Kidney Diseases; Male; Retrospective Studies; Tacrolimus; Time Factors | 1996 |
A logistic-regression model provides novel guidelines to maximize the anti-acute rejection properties of cyclosporine with a minimum of toxicity.
Topics: Adult; Cyclosporine; Dose-Response Relationship, Drug; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Logistic Models; Middle Aged; Models, Biological; Prospective Studies | 1996 |
Light microscopic and electron microscopic features of cyclosporine nephrotoxicity in rats.
Topics: Acute Disease; Animals; Body Weight; Chronic Disease; Cyclosporine; Immunosuppressive Agents; Kidney Diseases; Kidney Tubules; Male; Microscopy, Electron; Rats; Rats, Sprague-Dawley | 1995 |
[Cyclosporine and severe psoriasis].
Topics: Cyclosporine; Drug Interactions; Humans; Hypertension; Immunosuppressive Agents; Kidney Diseases; Psoriasis | 1996 |
Synergistic effects of cyclosporine and rapamycin in a chronic nephrotoxicity model.
Topics: Animals; Blood Glucose; Chronic Disease; Cyclosporine; Drug Synergism; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Polyenes; Rats; Rats, Sprague-Dawley; Sirolimus | 1996 |
Quinacrine attenuates cyclosporine-induced nephrotoxicity in rats.
Topics: Animals; Creatinine; Cyclosporine; Electrolytes; Free Radicals; Glutathione; Kidney; Kidney Diseases; Male; Malondialdehyde; Quinacrine; Rats; Rats, Wistar; Urea; Vitamin E | 1996 |
Regional differences in vasculotoxic effects of cyclosporin in rats.
Topics: Acetylcholine; Animals; Aorta; Carotid Arteries; Cyclosporine; Endothelium, Vascular; Immunosuppressive Agents; In Vitro Techniques; Kidney Diseases; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitroglycerin; Nitroprusside; Rats; Rats, Wistar; Renal Artery; Vascular Diseases; Vasodilator Agents | 1995 |
"Recurrence" of cyclosporine nephropathy in a heart transplant recipient.
Topics: Cyclosporine; Heart Transplantation; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Recurrence | 1996 |
Renal biopsy findings and followup of renal function in rheumatoid arthritis patients treated with cyclosporin A. An update from the International Kidney Biopsy Registry.
Topics: Adolescent; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Biopsy; Creatinine; Cyclosporine; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Kidney; Kidney Diseases; Male; Middle Aged; Risk Factors | 1996 |
Chronic renal allograft rejection: immunologic and nonimmunologic risk factors.
Topics: Adolescent; Adult; Child; Child, Preschool; Chronic Disease; Cohort Studies; Cyclosporine; Female; Graft Rejection; Humans; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Retrospective Studies; Risk Factors; Time Factors; Treatment Outcome | 1996 |
Cyclosporine nephrotoxicity in the ischemic kidney and the protective effect of pentoxifylline--a study in the rat.
Topics: Animals; Calcinosis; Creatinine; Cyclosporine; Ischemia; Kidney; Kidney Diseases; Kidney Tubules; Ligation; Microcirculation; Pentoxifylline; Prostaglandins; Rats; Rats, Sprague-Dawley; Thromboxane A2; Vacuoles; Vasoconstriction; Vasodilator Agents | 1996 |
Chronic cyclosporine nephrotoxicity in rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cyclosporine; Humans; Kidney Diseases; Organ Transplantation | 1996 |
Longterm low dose cyclosporine in patients with rheumatoid arthritis: renal function loss without structural nephropathy.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Biopsy; Cyclosporine; Female; Humans; Kidney; Kidney Diseases; Male; Middle Aged | 1996 |
Effects of a selective adenosine A1 receptor antagonist on the development of cyclosporin nephrotoxicity.
Topics: Animals; Blood Pressure; Cyclosporine; Drug Interactions; Glomerular Filtration Rate; Immunosuppressive Agents; Kidney Diseases; Male; Nifedipine; Purinergic Antagonists; Pyrazoles; Pyridines; Rats; Rats, Sprague-Dawley; Renal Plasma Flow, Effective; Vasodilator Agents | 1996 |
Cyclosporine nephrotoxicity and rejection crisis: diagnosis by urinary enzyme excretion.
Topics: Acetylglucosaminidase; Adult; CD13 Antigens; Cyclosporine; Diagnosis, Differential; Female; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged | 1996 |
Renal fibrosis in cyclosporin A-treated renal allograft recipients: morphological findings in relation to renal hemodynamics.
Topics: Adolescent; Adult; Aged; Biopsy, Needle; Cyclosporine; Female; Fibrosis; Follow-Up Studies; Glomerular Filtration Rate; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Postoperative Complications; Renal Circulation | 1996 |
Comparison of acute rapamycin nephrotoxicity with cyclosporine and FK506.
Topics: Animals; Cyclosporine; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Glomerulus; Kidney Tubules; Magnesium; Male; Polyenes; Rats; Rats, Sprague-Dawley; Sirolimus; Tacrolimus | 1996 |
Protective effect of L-propionylcarnitine on cyclosporine-induced nephrotoxicity.
Topics: Analysis of Variance; Animals; Carnitine; Cyclosporine; Dose-Response Relationship, Drug; Kidney Diseases; Male; Rats; Rats, Wistar | 1995 |
Study of neuromyopathy in amyloid kidney transplant patients.
Topics: Amyloidosis; Colchicine; Creatine Kinase; Cyclosporine; Electromyography; Evoked Potentials, Motor; Gout Suppressants; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; L-Lactate Dehydrogenase; Neuromuscular Diseases | 1996 |
Cyclosporin nephrotoxicity in heart and lung transplant patients.
Topics: Adult; Arterioles; Creatinine; Cyclosporine; Drug Administration Schedule; Female; Heart Transplantation; Heart-Lung Transplantation; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Lung Transplantation; Male; Middle Aged | 1996 |
The influence of temocapril, an angiotensin converting enzyme inhibitor, on the cyclosporine-induced nephrotoxicity.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Cyclosporine; Kidney Diseases; Male; Rats; Rats, Wistar; Thiazepines | 1997 |
Preventive effects of two PAF-antagonists, PMS 536 and PMS 549, on cyclosporin-induced LLC-PK1 oxidative injury.
Topics: Acetylglucosaminidase; Adenosine Diphosphate; Adenosine Triphosphate; Alkaline Phosphatase; Animals; Cyclosporine; Glutathione; Glutathione Peroxidase; Kidney Diseases; LLC-PK1 Cells; Oxidative Stress; Piperazines; Platelet Activating Factor; Platelet Aggregation Inhibitors; Swine | 1997 |
Possible use of excretion of tubular epithelial cells for the study of the nephrotoxic effect of xenobiotics.
Topics: Acetylglucosaminidase; Amphotericin B; Animals; Anti-Bacterial Agents; CD13 Antigens; Cyclosporine; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; Glomerular Filtration Rate; Hippurates; Immunosuppressive Agents; Iodine Radioisotopes; Kidney Diseases; Kidney Tubules; Male; Rats; Rats, Wistar; Toxicology; Urine; Xenobiotics | 1996 |
Cyclosporine monitoring with levels 6 hours after the morning dose in patients with noninfectious uveitis.
Topics: Adult; Aged; Creatine; Cyclosporine; Drug Monitoring; Female; Follow-Up Studies; Glomerular Filtration Rate; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Middle Aged; Prospective Studies; Recurrence; Technetium Tc 99m Pentetate; Uveitis | 1997 |
Effects of dietary sodium and magnesium on cyclosporin A-induced hypertension and nephrotoxicity in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Cyclosporine; Dose-Response Relationship, Drug; Drug Interactions; Hypertension; Immunosuppressive Agents; Kidney Diseases; Magnesium; Male; Rats; Rats, Inbred SHR; Sodium, Dietary | 1997 |
Cyclosporin A-induced changes in nitric oxide synthase activity in the rat kidney: in vitro and in vivo assay.
Topics: Animals; Cyclosporine; Immunosuppressive Agents; In Vitro Techniques; Kidney; Kidney Diseases; Male; Nitric Oxide Synthase; Proteins; Rats; Rats, Sprague-Dawley | 1996 |
Report on management of renale failure in Europe, XXVI, 1995. Rare diseases in renal replacement therapy in the ERA-EDTA Registry.
Topics: Adolescent; Adult; Aged; Cisplatin; Cyclosporine; Europe; Fabry Disease; Female; Humans; Kidney Diseases; Male; Middle Aged; Registries; Renal Replacement Therapy; Scleroderma, Systemic; Survival Rate | 1996 |
L-Arginine and allopurinol protect against cyclosporine nephrotoxicity.
Topics: Allopurinol; Animals; Arginine; Cyclosporine; Enzyme Inhibitors; Glomerular Filtration Rate; Inulin; Kidney Diseases; Male; Nitrates; Nitric Oxide; Nitrites; Potassium; Rats; Xanthine Oxidase | 1997 |
Renal biopsy findings in long-term cyclosporin treatment of psoriasis.
Topics: Adult; Aged; Biopsy, Needle; Cyclosporine; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Middle Aged; Psoriasis | 1997 |
Lazaroids prevent acute cyclosporine-induced renal vasoconstriction.
Topics: Animals; Antioxidants; Cyclosporine; Hemodynamics; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Pregnatrienes; Rats; Rats, Wistar; Renal Circulation | 1997 |
Reduction of chronic ciclosporin nephrotoxicity by thromboxane synthase inhibition with OKY-046.
Topics: Animals; Chronic Disease; Cyclosporine; Drug Evaluation, Preclinical; Enzyme Inhibitors; Kidney Diseases; Male; Methacrylates; Rats; Rats, Sprague-Dawley; Thromboxane A2; Thromboxane-A Synthase | 1997 |
Highly successful long-term outcome of kidney transplantation in Chinese recipients: an enhancing race effect?
Topics: Actuarial Analysis; Adolescent; Adult; Age Factors; Asian People; Black People; Cadaver; China; Cryopreservation; Culture; Cyclosporine; Female; Follow-Up Studies; Graft Survival; Haplotypes; Histocompatibility; HLA Antigens; Hong Kong; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Living Donors; Longitudinal Studies; Male; Middle Aged; Sex Factors; Time Factors; Treatment Outcome; White People | 1997 |
Prevention of cyclosporine-induced nephrotoxicity with dietary glycine.
Topics: Animal Feed; Animals; Cyclosporine; Diet; Eating; Glycine; Kidney; Kidney Diseases; Leukocytes; Macrophages; Male; Rats; Rats, Sprague-Dawley; Weight Gain | 1997 |
Sodium depletion enhances fibrosis and the expression of TGF-beta1 and matrix proteins in experimental chronic cyclosporine nephropathy.
Topics: Animals; Blood Pressure; Blotting, Northern; Creatinine; Cyclosporine; Extracellular Matrix Proteins; Fibrosis; Immunohistochemistry; Immunosuppressive Agents; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium; Transforming Growth Factor beta; Up-Regulation | 1997 |
Insulin-like growth factor-I ameliorates delayed kidney graft function and the acute nephrotoxic effects of cyclosporine.
Topics: Animals; Cyclosporine; Drug Synergism; Graft Rejection; Insulin-Like Growth Factor I; Kidney Diseases; Kidney Transplantation; Peptide Fragments; Rats; Rats, Inbred Lew; Rats, Inbred WF; Transplantation, Homologous | 1997 |
Angiotensin II blockade decreases TGF-beta1 and matrix proteins in cyclosporine nephropathy.
Topics: Angiotensin II; Animals; Blotting, Northern; Cyclosporine; Extracellular Matrix Proteins; Immunohistochemistry; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Plasminogen Activator Inhibitor 1; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transforming Growth Factor beta | 1997 |
Renal outcomes in pediatric liver transplantation.
Topics: Acidosis; Acute Kidney Injury; Adolescent; Adult; Age Factors; Child; Child, Preschool; Cyclosporine; Female; Follow-Up Studies; Glomerular Filtration Rate; Graft Rejection; Humans; Hypertension; Immunosuppressive Agents; Incidence; Infant; Kidney; Kidney Diseases; Kidney Transplantation; Liver Transplantation; Living Donors; Longitudinal Studies; Male; Renal Dialysis; Retrospective Studies; Sex Factors; Sodium Bicarbonate; Survival Rate; Treatment Outcome | 1997 |
Protective effects of dietary L-arginine supplementation on chronic cyclosporine nephrotoxicity.
Topics: Animals; Arginine; Blood Pressure; Cyclosporine; Enzyme Inhibitors; Fibrosis; Glomerular Filtration Rate; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Vascular Diseases | 1997 |
[The outlook for the use of cyclosporin A in rheumatology and nephrology].
Topics: Antirheumatic Agents; Cyclosporine; Humans; Kidney Diseases; Renal Agents; Rheumatic Diseases | 1997 |
Cyclosporine dose adjustment using levels obtained six hours after the morning dose: effect on side effects in patients with autoimmune diseases.
Topics: Adult; Aged; Autoimmune Diseases; Blood Pressure; Cohort Studies; Creatinine; Cyclosporine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Glomerular Filtration Rate; Humans; Hypertension; Immunosuppressive Agents; Kidney Diseases; Male; Middle Aged; Prospective Studies | 1997 |
Pentoxifylline reduces nephrotoxicity associated with cyclosporine in the rat by its rheological properties.
Topics: Animals; Arteries; Blood Pressure; Blood Viscosity; Cyclosporine; Hemodynamics; Kidney; Kidney Diseases; Male; Pentoxifylline; Rats; Rheology; Vasoconstriction; Vasodilator Agents | 1997 |
Chronic cyclosporin A nephrotoxicity, P-glycoprotein overexpression, and relationships with intrarenal angiotensin II deposits.
Topics: Angiotensin II; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Chronic Disease; Creatinine; Cyclosporine; Gene Expression Regulation; Immunoenzyme Techniques; Immunosuppressive Agents; Kidney Diseases; Kidney Tubules; Male; Rats; Rats, Sprague-Dawley; Urea | 1997 |
A novel approach to the treatment of chronic allograft nephropathy.
Topics: Adult; Cadaver; Chronic Disease; Cyclosporine; Female; Graft Rejection; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Mycophenolic Acid; Prednisone; Prospective Studies | 1997 |
Posttransplantation lymphoproliferative disorder: changing manifestations of disease in a renal transplant population.
Topics: Abdomen; Adolescent; Adult; Brain Diseases; Cyclosporine; Female; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Lymphoma; Lymphoproliferative Disorders; Magnetic Resonance Imaging; Male; Middle Aged; Muromonab-CD3; Radiography, Abdominal; Retrospective Studies; Survival Rate; Thoracic Diseases; Tomography, X-Ray Computed | 1997 |
Cyclosporine A nephrotoxicity: role of thromboxane and reactive oxygen species.
Topics: Animals; Body Weight; Cyclosporine; Free Radical Scavengers; Hydrogen Peroxide; Kidney Diseases; Kidney Glomerulus; Lipid Peroxides; Male; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxides; Thromboxane A2; Thromboxane B2; Vitamin E | 1998 |
The impact of cyclosporine dose and level on acute rejection and patient and graft survival in liver transplant recipients.
Topics: Adult; Cholesterol; Creatinine; Cyclosporine; Female; Graft Rejection; Graft Survival; Humans; Kidney Diseases; Liver Transplantation; Male; Middle Aged; Retrospective Studies; Survival Rate | 1998 |
Effect of 1 year cyclosporine A treatment on the activity and renal involvement of systemic lupus erythematosus: a pilot study.
Topics: Adult; Biopsy; Cyclosporine; Female; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Lupus Erythematosus, Systemic; Male; Methylprednisolone; Middle Aged; Pilot Projects | 1998 |
Impaired antioxidant defense system in the kidney tissues from rabbits treated with cyclosporine. Protective effects of vitamins E and C.
Topics: Animals; Antioxidants; Ascorbic Acid; Catalase; Cyclosporine; Cyclosporins; Drug Therapy, Combination; Enzyme Inhibitors; Glutathione Peroxidase; Kidney; Kidney Diseases; Kidney Glomerulus; Malondialdehyde; Rabbits; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Vitamin E | 1998 |
Long-term improvement in renal function after cyclosporine reduction in renal transplant recipients with histologically proven chronic cyclosporine nephropathy.
Topics: Adult; Aged; Biopsy; Blood Pressure; Chronic Disease; Creatinine; Cyclosporine; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Glomerular Filtration Rate; Humans; Kidney Diseases; Kidney Function Tests; Kidney Transplantation; Male; Middle Aged; Time Factors | 1998 |
Renal function after 10 years' treatment with cyclosporin for psoriasis.
Topics: Adult; Aged; Creatinine; Cyclosporine; Drug Administration Schedule; Female; Follow-Up Studies; Glomerular Filtration Rate; Humans; Hypertension; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Middle Aged; Psoriasis | 1998 |
Renal biopsy findings in long-term cyclosporin treatment of psoriasis.
Topics: Biopsy; Cyclosporine; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Psoriasis | 1998 |
The effect of silibinin on experimental cyclosporine nephrotoxicity.
Topics: Animals; Cyclosporine; Cytochrome P-450 Enzyme System; Female; Free Radical Scavengers; Glomerular Filtration Rate; Immunosuppressive Agents; Kidney Diseases; Lipid Peroxidation; Malondialdehyde; Microsomes, Liver; Mitochondria, Liver; Rats; Rats, Wistar; Silymarin | 1998 |
Importance of allograft biopsy in renal transplant recipients: correlation between clinical and histological diagnosis.
Topics: Adult; Aged; Biopsy, Needle; Cyclosporine; Diagnosis, Differential; Female; Graft Rejection; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Prospective Studies; Recurrence; Tacrolimus | 1998 |
Cyclosporine suppresses rat hepatic cytochrome P450 in a time-dependent manner.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androstenedione; Animals; Biomarkers; Creatinine; Cyclosporine; Cytochrome P-450 Enzyme System; Disease Models, Animal; Hydroxylation; Immunosuppressive Agents; Kidney Diseases; Kidney Function Tests; Liver; Male; Microsomes; Osmolar Concentration; Potassium; Rats; Rats, Sprague-Dawley; Testosterone; Time Factors | 1998 |
Time-dependent cyclosporine A-induced nephrotoxicity in rats.
Topics: Acetylglucosaminidase; Animals; Body Weight; Creatinine; Cyclosporine; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Rats; Rats, Wistar; Survival Rate; Time Factors | 1998 |
Effect of colchicine on chronic ciclosporin nephrotoxicity in Sprague-Dawley rats.
Topics: Animals; Body Weight; Colchicine; Cyclosporine; Immunosuppressive Agents; Kidney; Kidney Cortex; Kidney Diseases; Kidney Medulla; Male; Rats; Rats, Sprague-Dawley; Time Factors | 1998 |
Relation between urinary cytology abnormalities and cyclosporine A therapy in bone marrow transplant recipients.
Topics: Adult; Bone Marrow Transplantation; Cyclosporine; Female; Humans; Immunosuppressive Agents; Inclusion Bodies; Kidney Diseases; Male; Transplantation, Autologous; Transplantation, Homologous; Urinalysis; Urine | 1998 |
Changes in coagulation and fibrinolysis in the postoperative period immediately after kidney transplantation in patients receiving OKT3 or cyclosporine A as induction therapy.
Topics: Adult; Blood Coagulation; Blood Coagulation Factors; Cyclosporine; Female; Fibrinolysis; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Muromonab-CD3; Postoperative Complications; Renal Artery Obstruction; Thrombosis; Time Factors | 1998 |
[Treatment of the nephrotoxicity of immunosuppressive drugs with insulin-like growth factor-I].
Topics: Animals; Cyclosporine; Immunosuppressive Agents; Insulin-Like Growth Factor I; Kidney; Kidney Diseases; Kidney Transplantation; Male; Postoperative Complications; Rats; Rats, Inbred Lew; Tacrolimus | 1998 |
Is there a beneficial effect of the calcium channel blocker diltiazem on cyclosporine A nephrotoxicity in rats?
Topics: Animals; Body Weight; Calcium Channel Blockers; Cyclosporine; Cytochrome P-450 Enzyme System; Diltiazem; Drug Interactions; Ethylmorphine; Female; Glomerular Filtration Rate; Glutathione; Immunosuppressive Agents; Kidney; Kidney Diseases; Liver; Organ Size; p-Aminohippuric Acid; Rats; Rats, Wistar | 1998 |
Cyclosporine increases local glomerular synthesis of reactive oxygen species in rats: effect of vitamin E on cyclosporine nephrotoxicity.
Topics: Animals; Antioxidants; Cyclosporine; Kidney Diseases; Kidney Glomerulus; Lipid Peroxidation; Male; Malondialdehyde; Rats; Rats, Wistar; Reactive Oxygen Species; Vitamin E | 1998 |
The use of radiopharmaceuticals as an effective toxicologic technique for studying nephrotoxicity of drugs: cyclosporine-A.
Topics: Animals; Autoradiography; Creatinine; Cyclosporine; Kidney Diseases; Rabbits; Radioisotope Renography; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Wistar; Technetium Tc 99m Mertiatide; Urea | 1998 |
Lacidipine protects against cyclosporine-induced nephrotoxicity in rats.
Topics: Animals; Calcium Channel Blockers; Cyclosporine; Dihydropyridines; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Function Tests; Lipid Peroxidation; Lithium; Male; Rats; Rats, Wistar | 1999 |
Beneficial effect of serotonin 5-HT2-receptor antagonism on renal blood flow autoregulation in cyclosporin-treated rats.
Topics: Animals; Cyclosporine; Homeostasis; Kidney; Kidney Diseases; Male; Phenylephrine; Rats; Rats, Wistar; Regional Blood Flow; Renal Circulation; Ritanserin; Serotonin Antagonists | 1999 |
Aluminum exacerbates cyclosporin induced nephrotoxicity in rats.
Topics: Alum Compounds; Aluminum; Animals; Blood Urea Nitrogen; Creatinine; Cyclosporine; Dose-Response Relationship, Drug; Hydrogen Peroxide; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley | 1999 |
In vitro effects of simvastatin on tubulointerstitial cells in a human model of cyclosporin nephrotoxicity.
Topics: Aged; Cell Division; Cells, Cultured; Cholesterol; Cyclosporine; Female; Fibroblasts; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Cortex; Kidney Diseases; Kidney Tubules, Proximal; Male; Middle Aged; Permeability; Simvastatin; Sodium-Hydrogen Exchangers | 1999 |
Predictive value of Doppler ultrasonography in renal transplantation.
Topics: Cyclosporine; Graft Rejection; Humans; Immunosuppression Therapy; Kidney; Kidney Diseases; Kidney Transplantation; Sensitivity and Specificity; Ultrasonography | 1992 |
Cigarette smoking and renal function impairment.
Topics: Animals; Cyclosporine; Endothelins; Humans; Kidney Diseases; Renal Plasma Flow; Smoking | 1999 |
Melatonin: an antioxidant protects against cyclosporine-induced nephrotoxicity.
Topics: Animals; Antioxidants; Calcinosis; Creatinine; Cyclosporine; Kidney Diseases; Lithium; Male; Malondialdehyde; Melatonin; Nephrons; Rats; Rats, Wistar; Urea | 1999 |
Cyclosporine-induced nephrotoxicity in autoimmune diseases.
Topics: Autoimmune Diseases; Cyclosporine; Humans; Immunosuppressive Agents; Kidney Diseases | 1999 |
Mees' lines due to cyclosporin.
Topics: Adult; Cyclosporine; Drug Administration Schedule; Drug Overdose; Humans; Immunosuppressive Agents; Kidney Diseases; Male; Nail Diseases; Pigmentation Disorders | 1999 |
Cyclosporine-associated thrombotic microangiopathy in renal allografts.
Topics: Adolescent; Adult; Case-Control Studies; Cyclosporine; Female; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Tacrolimus; Thrombosis | 1999 |
Cyclosporin A nephrotoxicity in rats with genetically fixed hypertriglyceridemia.
Topics: Animals; Cyclosporine; Hypertriglyceridemia; Immunosuppressive Agents; Kidney Diseases; Kidney Function Tests; Rats; Triglycerides | 1999 |
Neoral monitoring by simplified sparse sampling area under the concentration-time curve: its relationship to acute rejection and cyclosporine nephrotoxicity early after kidney transplantation.
Topics: Acute Disease; Adult; Area Under Curve; Biological Availability; Cyclosporine; Dose-Response Relationship, Drug; Drug Monitoring; Female; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Time Factors | 1999 |
Optimization of the immunosuppressive protocol after lung transplantation.
Topics: Acute Disease; Adult; Animals; Antilymphocyte Serum; Azathioprine; Chronic Disease; Creatinine; Cyclosporine; Drug Therapy, Combination; Female; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Lung Transplantation; Male; Middle Aged; Mycophenolic Acid; Prednisone; Rabbits; Retrospective Studies; Tacrolimus | 1999 |
Mycophenolate mofetil monotherapy in stable liver transplant patients with cyclosporine-induced renal impairment: a preliminary report.
Topics: Creatinine; Cyclosporine; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Leukocyte Count; Liver Transplantation; Male; Methylprednisolone; Middle Aged; Mycophenolic Acid; Time Factors | 1999 |
Primary renal aspergillosis: extremely uncommon presentation in patients treated with bone marrow transplantation.
Topics: Aspergillosis; Aspergillus; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Cyclosporine; Fatal Outcome; Graft vs Host Disease; Humans; Immunosuppressive Agents; Kidney Diseases; Male; Middle Aged | 1999 |
Acute myopathy induced by colchicine in a cyclosporine treated heart transplant recipient: possible role of the multidrug resistance transporter.
Topics: Acute Disease; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chemical and Drug Induced Liver Injury; Colchicine; Cyclosporine; Drug Resistance, Multiple; Drug Therapy, Combination; Gastrointestinal Diseases; Gout Suppressants; Heart Transplantation; Humans; Immunosuppressive Agents; Kidney Diseases; Male; Middle Aged; Muscular Diseases; Syndrome | 1999 |
Expression of apoptosis regulatory genes in chronic cyclosporine nephrotoxicity favors apoptosis.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Northern; Blotting, Western; Caspase 3; Caspases; Chronic Disease; Creatinine; Cyclosporine; Fas Ligand Protein; Fibrosis; Fluorescent Antibody Technique; Gene Expression Regulation, Enzymologic; Immunosuppressive Agents; In Situ Nick-End Labeling; Kidney Diseases; Male; Membrane Glycoproteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tumor Suppressor Protein p53; Weight Gain | 1999 |
Is 3-hour cyclosporine blood level superior to trough level in early post-renal transplantation period?
Topics: Cyclosporine; Female; Graft Rejection; Humans; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Postoperative Period; Time Factors | 2000 |
Determination of the glomerular filtration rate (GFR): methodological problems, age-dependence, consequences of various surgical interventions, and the influence of different drugs and toxic substances.
Topics: Aging; Animals; Cyclosporine; Female; Fluorescein-5-isothiocyanate; Glomerular Filtration Rate; Humans; Inulin; Kidney; Kidney Diseases; Kinetics; Metals; Nephrectomy; Rats; Rats, Wistar; Species Specificity; Uremia | 1999 |
Acute cyclosporine A-induced nephrotoxicity: a rabbit model.
Topics: Acute Disease; Animals; Cyclosporine; Glycerol; Kidney; Kidney Diseases; Male; Rabbits; Renal Circulation; Surface-Active Agents | 2000 |
Lack of acute cyclosporine nephrotoxicity in late heart-transplant recipients.
Topics: Acute Disease; Atrial Natriuretic Factor; Biomarkers; Creatinine; Cyclosporine; Glomerular Filtration Rate; Graft Rejection; Heart Failure; Heart Transplantation; Humans; Immunosuppressive Agents; Kidney Diseases; Male; Middle Aged; Prognosis | 2000 |
The management of cyclosporine-induced nephrotoxicity after cardiac transplantation.
Topics: Cyclosporine; Heart Transplantation; Humans; Immunosuppressive Agents; Kidney Diseases; Mycophenolic Acid; Postoperative Complications | 2000 |
Conversion from tacrolimus to cyclosporine in stable renal transplant patients: safety, metabolic changes, and pharmacokinetic comparison.
Topics: Adult; Cholesterol; Cohort Studies; Cyclosporine; Graft Survival; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Middle Aged; Retreatment; Survival Analysis; Tacrolimus | 2000 |
A role for leukotrienes in cyclosporine nephrotoxicity.
Topics: Animals; Cyclosporine; Dicarboxylic Acids; Glomerular Filtration Rate; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Leukotriene Antagonists; Leukotriene E4; Leukotrienes; Male; Postoperative Period; Rats; Rats, Inbred Strains; Reference Values | 2000 |
Beneficial effects of dietary magnesium and potassium on cardiac and renal morphologic features in cyclosporin A-induced damage in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Coronary Circulation; Coronary Vessels; Cyclosporine; Heart Diseases; Immunosuppressive Agents; Kidney Diseases; Magnesium; Male; Potassium, Dietary; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Circulation; Sodium, Dietary | 2000 |
Comparison of enalapril and valsartan in cyclosporine A-induced hypertension and nephrotoxicity in spontaneously hypertensive rats on high-sodium diet.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Bradykinin; Bradykinin Receptor Antagonists; Cyclosporine; Dose-Response Relationship, Drug; Drinking; Eating; Electrolytes; Enalapril; Heart Rate; Hypertension; Hypertrophy, Left Ventricular; Kallikreins; Kidney; Kidney Diseases; Male; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; Renin; Sodium, Dietary; Tetrazoles; Urination; Valine; Valsartan | 2000 |
Change of treatment from cyclosporin to mycophenolate mofetil in severe psoriasis.
Topics: Aged; Cyclosporine; Female; Humans; Immunosuppressive Agents; Kidney Diseases; Male; Middle Aged; Mycophenolic Acid; Psoriasis; Severity of Illness Index; Treatment Outcome | 2000 |
Cyclosporin: nephro-protective as well as nephrotoxic?
Topics: Animals; Cell Adhesion Molecules; Cyclosporine; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Graft Rejection; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Rats; Serum Sickness; Tacrolimus; Transforming Growth Factor beta | 2000 |
Effect of nitric oxide modulation on TGF-beta1 and matrix proteins in chronic cyclosporine nephrotoxicity.
Topics: Animals; Arginine; Arterioles; Biglycan; Blood Pressure; Blotting, Northern; Chronic Disease; Collagen; Cyclosporine; Enzyme Inhibitors; Extracellular Matrix Proteins; Fibronectins; Fibrosis; Gene Expression; Glomerular Filtration Rate; Hyalin; Immunosuppressive Agents; Kidney Diseases; Kidney Glomerulus; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Plasminogen Activator Inhibitor 1; Proteoglycans; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transforming Growth Factor beta | 2000 |
Endothelin, angiotensin II and adenosine in acute cyclosporine A nephrotoxicity.
Topics: Acute Disease; Adenosine; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cyclosporine; Endothelins; Glomerular Filtration Rate; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Perindopril; Rabbits; Renal Circulation; Theophylline; Vascular Resistance; Water | 2000 |
Peritubular capillaries in chronic renal allograft rejection: a quantitative ultrastructural study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Basement Membrane; Capillaries; Child; Chronic Disease; Cyclosporine; Female; Graft Rejection; Humans; Kidney Diseases; Kidney Transplantation; Kidney Tubules; Male; Middle Aged; Sensitivity and Specificity; Transplantation, Homologous | 2000 |
Conversion to rapamycin immunosuppression in renal transplant recipients: report of an initial experience.
Topics: Adult; Blood Pressure; Cyclosporine; Female; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Lymphoproliferative Disorders; Male; Middle Aged; Pneumonia; Sirolimus; Tacrolimus | 2000 |
Cyclosporine A neurotoxicity in a patient with idiopathic renal magnesium wasting.
Topics: Brain; Child; Cyclosporine; Female; Heart Transplantation; Humans; Immunosuppressive Agents; Kidney Diseases; Magnesium Deficiency; Magnetic Resonance Imaging; Seizures | 2000 |
Tacrolimus has less fibrogenic potential than cyclosporin A in a model of renal ischaemia-reperfusion injury.
Topics: Animals; Creatinine; Cyclosporine; Fibrosis; Gene Expression; Immunosuppressive Agents; Kidney Diseases; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Proteinuria; Rats; Rats, Wistar; Renal Artery; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; Tacrolimus; Transforming Growth Factor beta | 2000 |
Immunohistochemical analysis of renin activity in chronic cyclosporine nephropathy in childhood nephrotic syndrome.
Topics: Adolescent; Arterioles; Child; Child, Preschool; Chronic Disease; Cyclosporine; Female; Humans; Immunohistochemistry; Infant; Juxtaglomerular Apparatus; Kidney; Kidney Diseases; Male; Nephrotic Syndrome; Renal Circulation; Renin | 2000 |
Clinical outcome after conversion to FK 506 (tacrolimus) therapy for acute graft-versus-host disease resistant to cyclosporine or for cyclosporine-associated toxicities.
Topics: Acute Disease; Adolescent; Adult; Bone Marrow Transplantation; Child; Child, Preschool; Cyclosporine; Drug Resistance; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Hemolytic-Uremic Syndrome; Humans; Immunosuppressive Agents; Kidney Diseases; Male; Middle Aged; Peripheral Nervous System Diseases; Retrospective Studies; Tacrolimus; Transplantation, Homologous; Treatment Outcome | 2000 |
Effect of anti-transforming growth factor-beta antibodies in cyclosporine-induced renal dysfunction.
Topics: Animals; Antibodies; Blotting, Northern; Cyclosporine; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Metalloendopeptidases; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Inhibitor of Metalloproteinases; Transforming Growth Factor beta | 2001 |
Chronic cyclosporin-induced nephropathy.
Topics: Chronic Disease; Cyclosporine; Follow-Up Studies; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Prognosis; Retrospective Studies | 2001 |
Vitamin E inhibits renal mRNA expression of COX II, HO I, TGFbeta, and osteopontin in the rat model of cyclosporine nephrotoxicity.
Topics: Animals; Antioxidants; Cyclosporine; Disease Models, Animal; Gene Expression; Heme Oxygenase (Decyclizing); Kidney; Kidney Diseases; Kidney Tubules; Male; Osteopontin; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sialoglycoproteins; Transforming Growth Factor beta; Vitamin E | 2001 |
Post-cyclosporine-mediated hypertension and nephropathy: amelioration by vascular endothelial growth factor.
Topics: Animals; Capillaries; Collagen; Cyclosporine; Endothelial Growth Factors; Hypertension, Renal; Immunosuppressive Agents; Kidney Diseases; Lymphokines; Macrophages; Male; Osteopontin; Rats; Rats, Sprague-Dawley; Renal Circulation; Sialoglycoproteins; Sodium Chloride, Dietary; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
Viral delivery of superoxide dismutase gene reduces cyclosporine A-induced nephrotoxicity.
Topics: Adenoviridae; Animals; beta-Galactosidase; Cyclosporine; Free Radical Scavengers; Free Radicals; Gene Transfer Techniques; Glomerular Filtration Rate; Kidney; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2001 |
Long-term impact of discontinued or reduced calcineurin inhibitor in patients with chronic allograft nephropathy.
Topics: Adrenal Cortex Hormones; Adult; Calcineurin; Chronic Disease; Cyclosporine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Mycophenolic Acid; Tacrolimus; Time Factors | 2001 |
Risk factors of cyclosporine nephrotoxicity after conversion from Sandimmune to Neoral.
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Creatinine; Cyclosporine; Female; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Logistic Models; Male; Middle Aged; Retrospective Studies; Risk Factors | 2001 |
Hyperuricemia exacerbates chronic cyclosporine nephropathy.
Topics: Animals; Chronic Disease; Collagen; Crystallization; Cyclosporine; Enzyme Inhibitors; Immunosuppressive Agents; Kidney; Kidney Diseases; Macrophages; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Osteopontin; Oxonic Acid; Rats; Rats, Sprague-Dawley; Reference Values; Sialoglycoproteins; Urate Oxidase; Uric Acid | 2001 |
Involvement of platelet-derived growth factor and histocompatibility of DRB 1 in chronic renal allograft nephropathy.
Topics: Adult; Cell Division; Cells, Cultured; Chronic Disease; Culture Media, Conditioned; Cyclosporine; DNA; Female; Histocompatibility; Histocompatibility Antigens Class I; Histocompatibility Antigens Class II; HLA-DR Antigens; HLA-DRB1 Chains; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; T-Lymphocytes; Transplantation, Homologous | 2001 |
A comparison between office and ambulatory blood pressure measurements in renal transplant patients with chronic transplant nephropathy.
Topics: Adult; Aged; Aged, 80 and over; Blood Pressure; Blood Pressure Determination; Blood Pressure Monitoring, Ambulatory; Chronic Disease; Circadian Rhythm; Cyclosporine; Female; Humans; Hypertension; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Function Tests; Kidney Transplantation; Male; Middle Aged; Tacrolimus | 2001 |
Renal function after pediatric cardiac transplantation: the effect of early cyclosporin dosage.
Topics: Child; Child, Preschool; Cyclosporine; Dose-Response Relationship, Drug; Female; Graft Rejection; Heart Transplantation; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Function Tests; Male | 2001 |
Expression of multidrug resistance P-glycoprotein in kidney allografts from cyclosporine A-treated patients.
Topics: Acute Disease; Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chronic Disease; Cyclosporine; Graft Rejection; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Kidney Tubular Necrosis, Acute; Middle Aged; Monocytes; Reference Values; Tissue Donors; Transplantation, Homologous; Tumor Necrosis Factor-alpha | 2001 |
Preconditioning with sodium arsenite inhibits apoptotic cell death in rat kidney with ischemia/reperfusion or cyclosporine-induced Injuries. The possible role of heat-shock protein 70 as a mediator of ischemic tolerance.
Topics: Animals; Apoptosis; Arsenites; Caspases; Cyclosporine; DNA Fragmentation; Gene Expression; HSP70 Heat-Shock Proteins; In Situ Nick-End Labeling; Ischemic Preconditioning; Kidney; Kidney Diseases; Kidney Tubular Necrosis, Acute; Male; Microscopy, Electron; Mitochondria; Rats; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Messenger; Sodium Compounds | 2001 |
Pathophysiology of cyclosporine-induced nephrotoxicity in humans: a role for nitric oxide?
Topics: 6-Ketoprostaglandin F1 alpha; Administration, Oral; Adult; Blood Pressure; Cyclosporine; Dinoprostone; Endothelins; Female; Heart Rate; Humans; Immunosuppressive Agents; Inulin; Kidney Diseases; Kidney Transplantation; Male; Metabolic Clearance Rate; Nitrates; Nitric Oxide; Nitrites; p-Aminohippuric Acid; Prostaglandins; Renal Artery; Renal Circulation; Thromboxane B2; Vascular Resistance; Vasoconstrictor Agents | 2001 |
The long-term effect of simultaneous heart and kidney transplantation on native renal function.
Topics: Aged; Cyclosporine; Female; Glomerular Filtration Rate; Heart Transplantation; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Postoperative Period; Radionuclide Imaging; Renal Circulation; Time Factors | 2001 |
Urine macrophage migration inhibitory factor concentrations as a diagnostic tool in human renal allograft rejection.
Topics: Adult; Cyclosporine; Diagnosis, Differential; Female; Graft Rejection; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Macrophage Migration-Inhibitory Factors; Male; Middle Aged; Osmolar Concentration; Prospective Studies; Retrospective Studies; Transplantation, Homologous | 2001 |
Outcome of cadaveric renal transplant patients treated for 10 years with cyclosporine: is chronic allograft nephropathy the major cause of late graft loss?
Topics: Adult; Azathioprine; Cadaver; Cyclosporine; Drug Therapy, Combination; Female; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Postoperative Complications; Postoperative Period; Prednisone; Survival Analysis; Time Factors; Treatment Outcome | 2001 |
Expression of vascular endothelial growth factor and its receptors Flt-1 and KDR/Flk-1 in chronic cyclosporine nephrotoxicity.
Topics: Animals; Chronic Disease; Cyclosporine; Diet, Sodium-Restricted; Endothelial Growth Factors; Immunosuppressive Agents; Kidney; Kidney Diseases; Lymphokines; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; RNA, Messenger; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factors | 2001 |
Daclizumab (humanized anti-IL2Ralpha mAb) prophylaxis for prevention of acute rejection in renal transplant recipients with delayed graft function.
Topics: Acute Disease; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Biopsy; Cyclosporine; Daclizumab; Dose-Response Relationship, Drug; Graft Rejection; Graft Survival; Humans; Immunoglobulin G; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Multicenter Studies as Topic; Postoperative Care; Randomized Controlled Trials as Topic; Retrospective Studies; Survival Analysis; Time Factors | 2001 |
[Study of renal transplant by deconvoluted renogram with 99m Tc-mercaptoacetyltriglycine (Mag3)].
Topics: Adult; Algorithms; Creatinine; Cyclosporine; Diuresis; Female; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Function Tests; Kidney Transplantation; Kidney Tubular Necrosis, Acute; Male; Postoperative Complications; Radionuclide Imaging; Radiopharmaceuticals; Renal Circulation; Sensitivity and Specificity; Technetium Tc 99m Mertiatide; Transplants; Urinary Retention | 2001 |
Conversion from cyclosporine to FK506 in adult liver transplant recipients: a combined North American and European experience.
Topics: Adult; Cyclosporine; Female; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Liver; Liver Function Tests; Liver Transplantation; Male; Middle Aged; Nervous System Diseases; Retreatment; Retrospective Studies; Salvage Therapy; Steroids; Tacrolimus | 2001 |
Does methylene blue protect the kidney tissues from damage induced by ciclosporin A treatment?
Topics: Animals; Coloring Agents; Cyclosporine; Dihydrolipoamide Dehydrogenase; Drug Combinations; Electron Transport Complex IV; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Tubules; Methylene Blue; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Thymus Gland | 2001 |
Renal allograft outcomes in African American versus Caucasian transplant recipients in the tacrolimus era.
Topics: Adult; Aged; Black People; Cyclosporine; Female; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Tacrolimus; Transplantation, Homologous; White People | 2001 |
Unequal racial access to kidney transplantation.
Topics: Black or African American; Coercion; Cost-Benefit Analysis; Cyclosporine; Federal Government; Government; Government Regulation; Health Care Rationing; Histocompatibility; Humans; Jurisprudence; Kidney; Kidney Diseases; Mandatory Programs; Mortality; Organ Transplantation; Organizational Policy; Patient Selection; Pharmaceutical Preparations; Policy Making; Prejudice; Prevalence; Prognosis; Public Policy; Reference Standards; Resource Allocation; Social Control, Formal; Social Justice; Statistics as Topic; Tissue and Organ Procurement; Tissue Donors; Transplantation; Treatment Outcome; United States; White People | 1993 |
Quercetin, a bioflavonoid, protects against oxidative stress-related renal dysfunction by cyclosporine in rats.
Topics: Animals; Antioxidants; Blood Pressure; Body Weight; Creatinine; Cyclosporine; Dose-Response Relationship, Drug; Drug Interactions; Female; Flavonoids; Kidney; Kidney Diseases; Kidney Function Tests; Lipid Peroxidation; Male; Oxidative Stress; Quercetin; Rats; Rats, Wistar; Water | 2001 |
Reciprocal regulation of cyclic GMP content by cyclic GMP-phosphodiesterase and guanylate cyclase in SHR with CsA-induced nephrotoxicity.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Body Weight; Cyclic GMP; Cyclosporine; Dose-Response Relationship, Drug; Guanylate Cyclase; Hypertension; Immunosuppressive Agents; In Vitro Techniques; Kidney; Kidney Diseases; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; Perfusion; Pressure; Rats; Rats, Inbred SHR; Vasodilator Agents | 2001 |
Cyclosporine A inhibits the adaptive responses to hypertonicity: a potential mechanism of nephrotoxicity.
Topics: Adaptation, Physiological; Animals; Apoptosis; Biological Transport; Cell Line; Cell Nucleus; Cyclosporine; DNA-Binding Proteins; Dogs; Gene Expression; Gene Expression Regulation; Heat-Shock Proteins; Humans; Hypertonic Solutions; Immunosuppressive Agents; Kidney Diseases; Kidney Medulla; Male; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; NFATC Transcription Factors; Osmotic Pressure; Rats; Rats, Sprague-Dawley; Response Elements; RNA, Messenger; Transcription Factors; Water-Electrolyte Balance | 2001 |
Transforming growth factor-beta1 and tumor growth factor-beta-inducible gene-H3 in nonrenal transplant cyclosporine nephropathy.
Topics: Adult; Cyclosporine; Extracellular Matrix Proteins; Heart Transplantation; Heart-Lung Transplantation; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Tubules, Distal; Middle Aged; Neoplasm Proteins; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2001 |
Cyclosporine nephrotoxicity: associated allograft dysfunction at low trough concentration.
Topics: Azathioprine; Child; Creatinine; Cyclosporine; Drug Therapy, Combination; Graft Rejection; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Male; Prednisolone | 2001 |
Course of glomerular filtration rate after renal transplantation and the influence of hypertension.
Topics: Adolescent; Child; Child, Preschool; Creatinine; Cyclosporine; Female; Glomerular Filtration Rate; Graft Rejection; Humans; Hypertension; Kidney Diseases; Kidney Transplantation; Male; Risk Factors; Time Factors | 2001 |
Long term results of liver-kidney transplantation in children with primary hyperoxaluria.
Topics: Adolescent; Adult; Child; Child, Preschool; Cyclosporine; Female; Graft Survival; Hip Joint; Humans; Hyperoxaluria; Immunosuppressive Agents; Infant; Kidney Diseases; Kidney Failure, Chronic; Kidney Transplantation; Liver Transplantation; Longitudinal Studies; Male; Postoperative Period; Radiography; Survival Analysis | 2001 |
One-year routine renal transplant biopsies in children.
Topics: Acute Disease; Adolescent; Adult; Aging; Biopsy; Child; Child, Preschool; Cryopreservation; Cyclosporine; Female; Graft Rejection; Humans; Immunosuppressive Agents; Incidence; Kidney; Kidney Diseases; Kidney Transplantation; Male; Postoperative Period; Renal Circulation; Time Factors; Vascular Diseases | 2001 |
Drug-induced renal dysfunction.
Topics: Aminoglycosides; Amphotericin B; Contrast Media; Cyclooxygenase Inhibitors; Cyclosporine; Humans; Intensive Care Units; Kidney Diseases | 2001 |
Autoantibodies against cytochrome P450s in sera of children treated with immunosuppressive drugs.
Topics: Adolescent; Adult; Antibody Specificity; Aryl Hydrocarbon Hydroxylases; Autoantibodies; Autoantigens; Azathioprine; Blotting, Western; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Cyclosporine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Therapy, Combination; Epitopes; Female; Graft Rejection; Humans; Immunoglobulin G; Immunosuppressive Agents; Infant; Isoenzymes; Kidney Diseases; Kidney Transplantation; Liver Cirrhosis, Biliary; Liver Transplantation; Male; Middle Aged; Mixed Function Oxygenases; Postoperative Complications; Prednisone; Recombinant Fusion Proteins; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Tacrolimus | 2002 |
[Effect of Consupren, Carvedilol and BL-443 on the composition of lactate dehydrogenase in tissues of rats with cyclosporin nephropathy].
Topics: Adrenergic Antagonists; Animals; Antihypertensive Agents; Carbamates; Carbazoles; Carvedilol; Cyclosporine; Immunosuppressive Agents; Isoenzymes; Kidney Diseases; L-Lactate Dehydrogenase; Liver; Lung; Male; Muscle, Skeletal; Myocardium; Propanolamines; Rats; Rats, Wistar; Spleen | 2002 |
Long-term renal allograft outcome after simultaneous kidney and pancreas transplantation.
Topics: Adult; Calcineurin Inhibitors; Case-Control Studies; Creatinine; Cyclosporine; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Incidence; Kidney; Kidney Diseases; Kidney Transplantation; Longitudinal Studies; Pancreas Transplantation; Retrospective Studies; Survival Analysis; Transplantation, Homologous; Treatment Outcome | 2002 |
Cyclosporine A neurotoxicity in a patient with idiopathic renal magnesium wasting.
Topics: Child; Cyclosporine; Female; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Magnesium Deficiency | 2002 |
Calcineurin inhibitor nephrotoxicity: reduction in dose results in marked improvement in renal function in patients with coexisting chronic allograft nephropathy.
Topics: Calcineurin Inhibitors; Chronic Disease; Creatinine; Cyclosporine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Transplantation, Homologous | 2002 |
Colchicine decreases apoptotic cell death in chronic cyclosporine nephrotoxicity.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspases; Colchicine; Cyclosporine; Immunosuppressive Agents; In Situ Nick-End Labeling; Kidney; Kidney Diseases; Male; Nephritis, Interstitial; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley | 2002 |
Melatonin prevents cyclosporine-induced nephrotoxicity in isolated and perfused rat kidney.
Topics: Animals; Antioxidants; Cyclosporine; Glomerular Filtration Rate; Immunosuppressive Agents; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Malondialdehyde; Melatonin; Nitrates; Nitrites; Perfusion; Rats; Rats, Wistar | 2002 |
European best practice guidelines for renal transplantation. Section IV: Long-term management of the transplant recipient. IV.2.1 Differential diagnosis of chronic graft dysfunction.
Topics: Calcineurin Inhibitors; Chronic Disease; Cyclosporine; Diagnosis, Differential; Graft Rejection; Humans; Kidney Diseases; Kidney Transplantation; Renal Artery Obstruction; Transplantation, Homologous; Ureteral Obstruction | 2002 |
Pirfenidone treatment decreases transforming growth factor-beta1 and matrix proteins and ameliorates fibrosis in chronic cyclosporine nephrotoxicity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biglycan; Calcinosis; Creatinine; Cyclosporine; Extracellular Matrix Proteins; Humans; Immunohistochemistry; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Tubules; Male; Proteoglycans; Pyridones; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription, Genetic; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2002 |
FK506-induced kidney tubular cell injury.
Topics: Acetylglucosaminidase; Animals; Cell Death; Cell Division; Cell Line; Cyclosporine; Endothelins; Kidney Diseases; Kidney Tubules; Swine; Tacrolimus | 1992 |
Plasma levels of endothelin in chronic renal failure and after renal transplantation: impact on hypertension and cyclosporin A-associated nephrotoxicity.
Topics: Adolescent; Adult; Aged; Creatinine; Cyclosporine; Endothelins; Female; Humans; Hypertension, Renal; Kidney Diseases; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Renal Dialysis; Time Factors | 1992 |
The restoration of ATP synthesis may explain the protective effect of calcium antagonists against cyclosporine A nephrotoxicity.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channels; Cyclosporine; Kidney; Kidney Diseases; Mitochondria, Liver; Nifedipine; Oxygen Consumption; Rats; Verapamil | 1992 |
Analgesic nephropathy and renal transplantation.
Topics: Adult; Analgesics; Cyclosporine; Graft Survival; Humans; Kidney Diseases; Kidney Transplantation; Middle Aged; Prognosis; Substance-Related Disorders; Urinary Bladder Neoplasms | 1992 |
Demographic factors influencing cyclosporine pharmacokinetic parameters in patients with uremia: racial differences in bioavailability.
Topics: Adult; Analysis of Variance; Biological Availability; Blood Chemical Analysis; Cyclosporine; Cytomegalovirus Infections; Female; Humans; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Models, Biological; Racial Groups; Regression Analysis; Uremia | 1992 |
Antagonist capacity of felodipine on cyclosporin A nephrotoxicity in the rat.
Topics: Absorption; Analysis of Variance; Animals; Cyclosporine; Felodipine; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley | 1992 |
A comparative study of cyclosporine vs FK 506: role of kidney microsomal cytochrome P-450.
Topics: Animals; Cyclosporine; Cytochrome P-450 Enzyme System; Kidney Diseases; Microsomes; Rats; Rats, Inbred Lew; Tacrolimus | 1992 |
Endothelin receptor antagonism is protective in in vivo acute cyclosporine toxicity.
Topics: Acute Disease; Animals; Cyclosporine; Endothelin Receptor Antagonists; Injections; Injections, Intra-Arterial; Injections, Intravenous; Kidney; Kidney Diseases; Male; Rats; Rats, Wistar; Renal Artery | 1992 |
How to improve the risk-benefit ratio of cyclosporin therapy for psoriasis.
Topics: Cyclosporine; Drug Therapy, Combination; Humans; Kidney Diseases; Methotrexate; Psoriasis; PUVA Therapy; Retinoids | 1992 |
The use of lithium clearance studies in the early detection of cyclosporin A (CsA) nephrotoxicity: a protocol of renal function assessment with CsA therapy.
Topics: Chronic Disease; Creatinine; Cyclosporine; Humans; Kidney Diseases; Kidney Function Tests; Lithium; Uveitis, Posterior | 1992 |
Immunohistochemical markers of renal tubular injury and cyclosporin nephrotoxicity in kidney allograft biopsies.
Topics: Biopsy; Cyclosporine; Diagnosis, Differential; Graft Rejection; Humans; Immunohistochemistry; Kidney Diseases; Kidney Transplantation; Kidney Tubules; Transplantation, Homologous | 1992 |
Severe tubulopathy and kidney graft rupture after coadministration of mannitol and ciclosporin.
Topics: Adult; Biopsy; Creatinine; Cyclosporine; Graft Rejection; Humans; Immunosuppressive Agents; Injections, Intravenous; Kidney; Kidney Diseases; Kidney Transplantation; Kidney Tubules; Male; Mannitol; Rupture, Spontaneous; Transplantation, Homologous | 1992 |
Advantages of cyclosporine as sole immunosuppressive agent in children with transplanted kidneys.
Topics: Adolescent; Body Height; Child; Cyclosporine; Female; Graft Survival; Humans; Hypertension; Kidney Diseases; Kidney Transplantation; Male; Nutritional Status; Prospective Studies | 1992 |
Cyclosporine nephrotoxicity in lung transplant recipients.
Topics: Adult; Creatinine; Cyclosporine; Female; Graft Survival; Humans; Kidney Diseases; Kidney Function Tests; Lung Diseases; Lung Transplantation; Male; Middle Aged | 1992 |
[Low dose cyclosporin treatment for ocular lesions of Behçet's disease].
Topics: Adult; Behcet Syndrome; Cyclosporine; Drug Administration Schedule; Female; Humans; Kidney Diseases; Male; Middle Aged; Nervous System Diseases | 1992 |
[Clinical study on drug-induced nephropathy].
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Cyclosporine; Drug Delivery Systems; Female; Humans; Kidney; Kidney Diseases; Male | 1992 |
Amelioration of experimental cyclosporine nephrotoxicity by calcium channel inhibition.
Topics: Animals; Calcium Channel Blockers; Cyclosporine; Diltiazem; Glomerular Filtration Rate; Kidney; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; Renal Circulation; Thromboxane B2 | 1992 |
The effects of pentoxifylline on experimental chronic cyclosporine nephrotoxicity.
Topics: Animals; Cyclosporine; Fibrosis; Kidney; Kidney Diseases; Male; Pentoxifylline; Rats; Rats, Sprague-Dawley | 1992 |
Correlation of cyclosporine-induced nephropathy with renal microsomal cytochrome P-450: the preventive effect of verapamil.
Topics: Animals; Cyclosporine; Cytochrome P-450 Enzyme System; Kidney; Kidney Diseases; Male; Microsomes; Rats; Rats, Inbred Strains; Verapamil | 1992 |
Differential diagnosis of kidney transplant rejection and cyclosporine nephrotoxicity by urine cytology.
Topics: Adult; Antigens, CD; Cyclosporine; Diagnosis, Differential; Female; Graft Rejection; Humans; Kidney Diseases; Kidney Transplantation; Lymphocyte Subsets; Male | 1992 |
Long-term results of cyclosporin A therapy in children.
Topics: Adolescent; Antihypertensive Agents; Azathioprine; Child; Child, Preschool; Cyclosporine; Female; Follow-Up Studies; Graft Survival; Growth Disorders; Humans; Hyperlipidemias; Hypertension; Kidney Diseases; Kidney Function Tests; Kidney Transplantation; Male; Postoperative Complications; Prednisolone; Retrospective Studies; Treatment Outcome | 1992 |
Renal function and blood pressure in patients receiving long-term, low-dose cyclosporine therapy for idiopathic autoimmune uveitis.
Topics: Adult; Autoimmune Diseases; Cholesterol; Creatinine; Cyclosporine; Drug Administration Schedule; Female; Follow-Up Studies; Glomerular Filtration Rate; Humans; Hypertension; Kidney Diseases; Male; Middle Aged; Potassium; Triglycerides; Uric Acid; Uveitis | 1992 |
Monitoring and prevention of renal dysfunction in cardiac transplant recipients.
Topics: Cyclosporine; Drug Monitoring; Gout; Heart Transplantation; Humans; Hypertension; Kidney Diseases; Postoperative Complications | 1992 |
Detection of nephrotoxicity in cyclosporine-A amyotrophic lateral sclerosis patients by means of urinary cytology.
Topics: Amyotrophic Lateral Sclerosis; Biopsy, Needle; Cyclosporine; Female; Humans; Kidney Diseases; Male; Middle Aged; Time Factors | 1992 |
Renal transplantation in elderly recipients.
Topics: Age Factors; Aged; Azathioprine; Cyclosporine; Female; Follow-Up Studies; Graft Rejection; Humans; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Renal Dialysis; Retrospective Studies; Time Factors | 1992 |
Comparison of the effects of cyclosporine and its metabolites on the release of prostacyclin and endothelin from mesangial cells.
Topics: Animals; Cells, Cultured; Cyclosporine; Endothelins; Epoprostenol; Glomerular Mesangium; Kidney Diseases; Rabbits | 1992 |
Alterations in renal function in psoriasis patients treated with cyclosporine, 5 mg/kg/day.
Topics: Adult; Aged; Creatinine; Cyclosporine; Drug Administration Schedule; Female; Humans; Kidney Diseases; Male; Middle Aged; Psoriasis | 1992 |
[An investigation of cyclosporine A (CyA) nephrotoxicity by lithium clearance].
Topics: Animals; Cyclosporine; Isotonic Solutions; Kidney; Kidney Diseases; Kidney Function Tests; Lithium; Male; Rats; Rats, Inbred Strains | 1992 |
Schistosomal nephropathy: effect of ciclosporin A (CsA) in murine schistosomiasis mansoni.
Topics: Animals; Cyclosporine; Kidney Diseases; Liver; Mice; Organ Size; Schistosomiasis mansoni; Spleen | 1992 |
Spontaneous renal allograft rupture: a disappearing phenomenon in the cyclosporine era?
Topics: Adult; Azathioprine; Cyclosporine; Female; Graft Rejection; Humans; Immunosuppression Therapy; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Prednisolone; Rupture, Spontaneous | 1992 |
Risk factors for cyclosporine-induced nephropathy in patients with autoimmune diseases. International Kidney Biopsy Registry of Cyclosporine in Autoimmune Diseases.
Topics: Adolescent; Adult; Age Factors; Autoimmune Diseases; Blood Pressure; Creatinine; Cyclosporine; Diabetes Mellitus, Type 1; Female; Humans; Kidney; Kidney Diseases; Male; Middle Aged; Multivariate Analysis; Psoriasis; Retrospective Studies; Risk Factors; Sjogren's Syndrome; Uveitis | 1992 |
Cyclosporine therapy for autoimmune disease.
Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Behcet Syndrome; Cyclosporine; Diabetes Mellitus, Type 1; Humans; Kidney Diseases; Psoriasis | 1992 |
A pilot study to assess the ability of an orally available selective thromboxane synthase inhibitor to improve renal function in cyclosporine-treated renal transplant recipients.
Topics: Administration, Oral; Adult; Cyclosporine; Eicosanoids; Female; Hemodynamics; Humans; Kidney; Kidney Diseases; Kidney Transplantation; Male; Pilot Projects; Pyridines; Thromboxane-A Synthase | 1992 |
Effect of ciclosporin on cardiac output and regional blood flow in rats: ciclosporin-induced nephropathy and its prevention with calcium channel blocker.
Topics: Animals; Cardiac Output; Cyclosporine; Hemodynamics; Ischemia; Kidney; Kidney Diseases; Male; Rats; Rats, Inbred Strains; Regional Blood Flow; Renal Circulation; Verapamil | 1992 |
Serum levels of alpha-1 microglobulin and beta-2 microglobulin in bone marrow transplant recipients treated with cyclosporin A.
Topics: Adolescent; Adult; Alpha-Globulins; beta 2-Microglobulin; Bone Marrow Transplantation; Child; Creatinine; Cyclosporine; Female; Graft vs Host Disease; Humans; Infections; Kidney; Kidney Diseases; Male; Middle Aged; Protease Inhibitors | 1991 |
[Anticytoplasmic antibodies in Wegener's granulomatosis and other kidney diseases].
Topics: Autoantibodies; Autoimmune Diseases; Combined Modality Therapy; Cyclosporine; Cytoplasm; Fluorescent Antibody Technique; Granulomatosis with Polyangiitis; Humans; Kidney Diseases; Nephrotic Syndrome; Plasmapheresis | 1991 |
[Therapeutic aspects of Wegener's granulomatosis].
Topics: Adult; Aged; Aged, 80 and over; Combined Modality Therapy; Creatinine; Cyclophosphamide; Cyclosporine; Female; Granulomatosis with Polyangiitis; Humans; Kidney Diseases; Lung Diseases; Male; Middle Aged; Plasmapheresis; Prednisolone; Retrospective Studies; Survival Rate; Trimethoprim, Sulfamethoxazole Drug Combination | 1991 |
[Effects of verapamil on cyclosporine. A (CsA)-induced nephropathy in ischemic kidney model in rats: changes in systemic hemodynamics and hepatic and renal microsomal cytochrome P-450].
Topics: Animals; Cyclosporine; Cytochrome P-450 Enzyme System; Disease Models, Animal; Enzyme Induction; Hemodynamics; Ischemia; Kidney; Kidney Diseases; Microsomes; Microsomes, Liver; Nephrectomy; Rats; Rats, Inbred Strains; Renal Circulation; Verapamil | 1991 |
Mechanisms of cyclosporine A toxicity in defined cultures of renal tubule epithelia: a role for cysteine proteases.
Topics: Animals; Calcium; Cell Death; Cells, Cultured; Cyclosporine; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Diltiazem; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; Humans; Kidney Diseases; Kidney Tubules; Leucine; Microscopy, Fluorescence; Nifedipine; Rabbits; Time Factors; Verapamil | 1991 |
[Usefulness of ketoconazole combined with cyclosporin in renal transplantation].
Topics: Adolescent; Adult; Azathioprine; Biotransformation; Chemical and Drug Induced Liver Injury; Cyclosporine; Cytochrome P-450 Enzyme Inhibitors; Drug Therapy, Combination; Female; Humans; Immunosuppression Therapy; Ketoconazole; Kidney Diseases; Kidney Transplantation; Liver Function Tests; Male; Middle Aged; Prednisone | 1991 |
[Functional reversibility of chronic cyclosporine nephrotoxicity in patients after kidney transplantation].
Topics: Chronic Disease; Cyclosporine; Female; Humans; Kidney; Kidney Diseases; Kidney Function Tests; Kidney Transplantation; Time Factors | 1991 |
[Effect of verapamil on cyclosporine-induced vasoconstriction in human or murine isolated glomerules].
Topics: Animals; Cyclosporine; Depression, Chemical; Humans; In Vitro Techniques; Kidney; Kidney Diseases; Male; Rats; Stimulation, Chemical; Vasoconstriction; Verapamil | 1991 |
Reduced nephrotoxicity and hepatoxicity in cyclosporin A therapy by enalapril and spironolactone in rats.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cyclosporine; Drug Therapy, Combination; Enalapril; Kidney Diseases; Liver Diseases; Male; Rats; Rats, Sprague-Dawley; Spironolactone | 1991 |
Effect of timing of cyclosporine administration on recovery from renal ischemia in rats.
Topics: Animals; Creatinine; Cyclosporine; Ischemia; Kidney; Kidney Diseases; Male; Rats; Rats, Inbred Strains; Time Factors | 1991 |
Therapeutic drug monitoring of cyclosporine-lipoprotein levels.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Cyclosporine; Female; Humans; Kidney Diseases; Lipoproteins; Male; Middle Aged | 1991 |
Comparison of cyclosporine blood levels measured by radioimmunoassay and TDx assay using monoclonal antibodies.
Topics: Adult; Aged; Antibodies, Monoclonal; Cyclosporine; Fluorescence Polarization Immunoassay; Graft Rejection; Humans; Kidney Diseases; Kidney Transplantation; Middle Aged; Radioimmunoassay; Sensitivity and Specificity | 1991 |
A comparison of cyclosporine A and Nva2-cyclosporine (cyclosporine G) in a rat renal allograft model.
Topics: Animals; Cyclosporine; Cyclosporins; Drug Evaluation, Preclinical; Graft Rejection; Kidney Diseases; Kidney Transplantation; Male; Rats; Rats, Inbred Lew; Transplantation, Homologous | 1987 |
Nephrotoxicity of cyclosporine A and cyclosporine G in a rat model.
Topics: Animals; Blood Pressure; Creatinine; Cyclosporine; Cyclosporins; Glomerular Filtration Rate; Kidney Cortex; Kidney Diseases; Male; Rats; Rats, Inbred Strains; Renal Circulation | 1988 |
An assessment of Nva2-cyclosporine in primate cardiac transplantation.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cyclosporine; Cyclosporins; Heart Transplantation; Immunosuppression Therapy; Kidney Diseases; Macaca fascicularis; Myocardium; Time Factors | 1987 |