cyclosporine has been researched along with Ischemia in 133 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (0.75) | 18.7374 |
1990's | 80 (60.15) | 18.2507 |
2000's | 34 (25.56) | 29.6817 |
2010's | 15 (11.28) | 24.3611 |
2020's | 3 (2.26) | 2.80 |
Authors | Studies |
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Cheng, Y; Huan, M; Ji, Q; Liu, D; Liu, M; Mei, Q; Zhang, B; Zhou, S | 1 |
Dehpour, AR; Ghasemnejad-Berenji, M; Majdani, R; Yazdani, I | 1 |
Baetz, D; Bidaux, G; Guebre-Egziabher, F; Juillard, L; Lemoine, S; Pillot, B; Rozes, M; Schleef, M | 1 |
Domingues, MAC; Módolo, NSP; Oliveira, ACC; Schwingel, PA | 1 |
Carvalho, LR; Castiglia, YM; Deffune, E; Golim, MA; Lemos, SV; Módolo, NS; Nascimento, PD; Souza, AV; Vianna, IG; Vianna, PT | 1 |
Alexis, J; Khosrotehrani, K; Patel, J; Roy, E; Shafiee, A; Sim, SL | 1 |
Agu, E; Cortez-Toledo, E; Dahlenburg, H; Nolta, JA; Rose, M; Yao, W; Zhou, P | 1 |
Elmér, E; Hansson, MJ; Hatakeyama, K; Morota, S; Nishiyama, T; Suzuki, M; Taguchi, C; Tanoue, T; Uchino, H; Usui, D | 1 |
Ju, WK; Kim, KY; Kim, SY; Shim, MS; Weinreb, RN; Wheeler, LA | 1 |
Chen, H; Chen, Z; Li, A; Liu, C; Sun, Y; Wang, D; Xu, J; Yin, J; Zhang, Z; Zhu, J | 1 |
Cologna, AJ; Lima, LV; Martins, AC; Reis, RB; Rodrigues, AA; Suaid, HJ; Tirapelli, LF; Tucci, S | 1 |
Chen, WS; Huang, DF; Wang, HP; Young, AH | 1 |
Broekema, M; Harmsen, MC; Koerts, JA; Navis, G; Petersen, AH; Popa, ER; Uges, DR; van Kooten, TG; van Luyn, MJ | 1 |
Itoh, K; Katayama, I; Morita, A; Sano, S; Takahashi, Y; Yamaguchi, Y | 1 |
Bernacki, J; Gabryel, B | 1 |
Barbier, S; Bellien, J; Etienne, I; Godin, M; Hurault de Ligny, B; Iacob, M; Joannides, R; Lebranchu, Y; Thuillez, C | 1 |
Erlandsson, A; Lin, CH; Morshead, CM; Yu, F | 1 |
Bernacki, J; Bielecka, A; Gabryel, B; Herman, ZS; Łabuzek, K | 1 |
Horvath, G; Kiss, P; Laszlo, E; Lubics, A; Racz, B; Reglodi, D; Szakaly, P; Tamas, A | 1 |
Komiya, T; Muso, E | 1 |
Aubard, Y; Bertin, F; Cornuejols, MJ; Couquet, C; Essig, M; Fourcade, L; Gauthier, T; Marquet, P; Maubon, A; Piver, P; Plainard, X; Pommepuy, I; Saint Marcoux, F | 1 |
Bergwerf, I; De Vocht, N; Everaert, BR; Ponsaerts, P; Timmermans, JP; Van Der Linden, A; Vrints, CJ | 1 |
Hasenkam, JM; Moosdorf, R; Nygaard, H; Troitzsch, D; Vogt, S | 1 |
Au-Yeung, KK; O, K; Siow, YL; Wang, G; Zhu, T | 1 |
Adamchik, Y; Carlen, PL; Frantseva, M; Perez Velazquez, JL; Tonkikh, A | 1 |
Baelde, HJ; Bruijn, JA; De Heer, E; Lagaaij, EL; Paul, LC; Xu, W | 1 |
Ahn, HJ; Bang, BK; Choi, BS; Jung, JY; Kim, HW; Kim, J; Kim, WY; Kim, YS; Li, C; Moon, IS; Yang, CW | 1 |
Kim, JS; Lemasters, JJ; Qian, T | 1 |
Fujikawa, K; Kishi, Y; Naito, K; Takai, K; Tsuchida, M; Uchiyama, K | 1 |
Ahmed, A; El Nahas, AM; Haylor, J; Ismail, W; Karim, M; Raftery, A; Shortland, J | 1 |
Davis, NA; Inman, SR; Lukaszek, VA; Olson, KM | 1 |
Davis, NA; Inman, SR; Lukaszek, VA; McKinley, MR; Olson, KM; Seminerio, JL | 1 |
French, ME; Homan, WP; Morris, PJ | 1 |
Dawidson, I; Lu, C; Palmer, B; Peters, P; Risser, R; Rooth, P; Sagalowsky, A; Sandor, Z | 1 |
Ahmed, A; Ahmed, AK; El Nahas, AM; Fahmy, H; Haylor, JL; Huang, L; Raftery, AT | 1 |
Azizian, M; Bruch, D; Kittur, DS; Ramenaden, ER; Shah, G; Wilasrusmee, C | 1 |
Morin, D; Pires, F; Plin, C; Tillement, JP | 1 |
Fukuhara, N; Hattori, R; Kamihira, O; Kinukawa, T; Nishiyama, N; Ohshima, S; Ono, Y; Yamada, S | 1 |
Conlon, PJ; Donohue, J; Giblin, L; Hickey, D; Little, D; O'Kelly, P; Spencer, S; Walshe, JJ | 1 |
Abdelmalek, MF; Gagliardi, R; Granger, D; Holt, C; Kam, I; Klintmalm, G; Langnas, A; Lucey, MR; Shetty, K; Tzakis, A; Woodle, ES | 1 |
Cao-Danh, H; Choi, YH; Cowan, DB; del Nido, PJ; Friehs, I; McGowan, FX; Nathan, M | 1 |
Barthen, ER; Chan, WY; de Wolff-Rouendaal, D; Emmanouilidis-van der Spek, K; Jager, MJ; Jovanovik-Pandova, L; Liu, C; Watson, PG | 1 |
Asselman, M; D'Haese, PC; De Broe, ME; De Naeyer, S; Gwinner, W; Mengel, M; Verhulst, A; Verkoelen, CF; Vervaet, BA | 1 |
Szegedi, J | 1 |
Cherng, WJ; Hsu, CM; Lan, YJ; Verma, S; Wang, CH; Wang, JS; Yang, NI; Yeh, CH | 1 |
Dhar, DK; Nagasue, N; Nakamura, T; Takemoto, Y; Tsuchiya, M; Uchida, M; Yamanoi, A; Yoshimura, H | 1 |
Bowen, CV; Boyer, MI; Danska, JS; Kiral, A; Nolan, L | 1 |
Ascher, NL; Ferrell, L; Freise, CE; Liu, T; Osorio, RW; Roberts, JP | 1 |
Andersen, HO; Hansen, BF; Holm, P; Kjeldsen, K; Nordestgaard, BG; Stender, S | 1 |
Bia, MJ | 1 |
Cejalvo, D; Rodriguez, FJ; Suzuki, S; Toledo-Pereyra, LH | 1 |
Barceló, P; García-Alonso, I; Méndez, J; Portugal, V | 1 |
Barceló, P; Echevarría, MI; García-Alonso, I; Méndez, J; Portugal, V | 1 |
Azuma, H; Hancock, WW; Heemann, UW; Pradham, P; Tilney, NL; Tullius, SG | 1 |
Akutsu, H; Fujita, T; Hoshinaga, K; Kanno, T; Naide, Y; Nishiyama, N; Sasaki, H; Shinoda, M; Tsukiashi, Y; Yanaoka, M | 1 |
Abramowicz, D; De Pauw, L; Goldman, M; Kahana, L; Kinnaert, P; Monaco, AP; Norman, DJ; Shield, CF; Thistlethwaite, JR; Vanherweghem, JL | 1 |
Ar'Rajab, A; Dawidson, IJ; Harris, RB; Sentementes, JT | 1 |
Ar'Rajab, A; Dawidson, IJ; Harris, RB; Mileski, WJ; Sentementes, JT | 1 |
Barkworth, E; Cope, GH; el Nahas, A; Raftery, AT; Shehata, M | 1 |
Andersen, HO; Holm, P; Kjeldsen, K; Nordestgaard, BG; Stender, S | 1 |
Endo, T; Kumano, K; Mashimo, S; Soh, S; Utsunomiya, T | 1 |
Ishii, T; Kai, T; Kim, YI; Kitamura, H; Kobayashi, M; Tatsuma, T | 1 |
Chen, CS; Chen, HW; Chu, SH; Chuang, CK; Huang, CC; Lai, MK | 1 |
Akizuki, S; Goto, S; Kawano, K; Kim, YI | 1 |
Akizuki, S; Ishii, T; Kai, T; Kim, YI; Kobayashi, M; Ono, M; Tatsuma, T | 1 |
Bohdanecká, M; Chadimová, M; Petrásek, B; Reitschlägerová, V; Schück, O | 1 |
Hirao, Y; Kagebayashi, Y; Okajima, E; Ota, M; Ozono, S; Saka, T; Tani, M; Yoneda, T; Yoshida, K | 1 |
Bouchier-Hayes, D; Creagh, T; Dolan, J; Lanigan, D; Tormey, W; Walshe, JJ | 1 |
Beckingham, IJ; Blamey, RW; Dennis, MJ | 1 |
Barceló, P; Bilbao, J; García-Alonso, I; Méndez, J; Múgica, P; Portugal, V | 1 |
Burdick, JF; Keown, P; Marcussen, N; Olsen, S; Racusen, LC; Slatnik, I; Solez, K | 1 |
Cacciarelli, TV; Ding, Z; Hong, JH; Sommer, BG; Sumrani, N | 1 |
Abramowicz, D; De Pauw, L; Goldman, M; Haverty, TP; Kahana, L; Kinnaert, P; Monaco, A; Norman, DJ; Shield, CF; Stuart, FP; Thistlethwaite, JR; Vanherweghem, JL; Vereerstraeten, P; Wu, SC | 1 |
Brooks, DP | 1 |
Ates, E; Erkasap, S; Ihtiyar, E; Kiper, H; Sharma, P; Talbot, D; Yasar, B | 1 |
Ayan, F; Bilgic, L; Cetinkale, O; Kandilci, A | 1 |
Bachmann, P; Binswanger, U; Gantenbein, H; Huynh, U; Largiadèr, F; Schlumpf, R; Steinhäuslin, F; Weinreich, T | 1 |
Hewitt, CW; Puglisi, RN; Santos, M; Schulte, G; Strande, L; Whalen, TV | 1 |
Ajzen, H; Barros, EG; Boim, MA; Cardoso, LR; Santos, OF; Schor, N | 1 |
Hisanaga, E; Sai, Y; Tamai, I; Terao, T; Tsuji, A | 1 |
Barros, EJ; Boim, MA; dos Santos, OF; Schor, N | 1 |
Conger, J | 1 |
Codaccioni, MX; Coppin, MC; Hazzan, M; Labalette, M; Lelièvre, G; Noël, C; Pruvot, FR | 1 |
Berquist, WE; Cox, KL; Esquivel, CO; Lang, T; Sendl, AF | 1 |
Bohdanecká, M; Chadimová, M; Petrásek, R; Reitschlägerová, V; Schück, O | 1 |
McAnulty, JF | 1 |
Andoh, TF; Bennett, WM; Couser, WG; Johnson, RJ; Pichler, RH; Shankland, SJ; Thomas, SE | 1 |
Oyanagui, Y | 1 |
Fabia, R; Goldstein, RM; Husberg, BS; Klintmalm, GB; Levy, MF; Netto, GG; Travis, DL | 1 |
Kusano, T; Muto, Y; Nagahama, M; Obuchi, Y; Shiraishi, M; Sugawa, H; Taira, K; Tomori, H | 1 |
Cetinkale, O; Konukoglu, D; Taşci, I | 1 |
Bechstein, WO; Egermann, F; Jonas, S; Neuhaus, P; Nieminen, M; Pratschke, J; Qun, Y; Reutzer-Selke, A; Tullius, SG; Volk, HD | 1 |
Bernardi, P; Di Lisa, F | 1 |
Bourdel-Marchasson, I; Canioni, P; Delmas-Beauvieux, MC; Diolez, P; Dufour, S; Gallis, JL; Leducq, N | 1 |
Fujita, T; Hatsuse, K; Hattori, R; Kinukawa, T; Ohshima, S; Ono, Y | 1 |
Almogy, N; Fiodorov, D; Nakache, R; Weinbroum, A | 1 |
el-Assal, ON; Nagasue, N; Soda, Y; Yu, L | 1 |
Beato, F; Kato, S; Kusaka, M; Nagano, H; Shaw, GD; Tilney, NL; Zandi-Nejad, K | 1 |
Maksoud, JG; Maksoud-Filho, JG; Rodrigues, CJ; Tannuri, U | 1 |
Boom, H; de Fijter, J; Paul, LC | 1 |
de Bruin, RW; Heemann, UW; Ijzermans, JN; Kouwenhoven, EA; Marquet, RL | 1 |
Nilsson, M; Sims, NR; Zaidan, E | 1 |
Almogy, N; Fiodorov, D; Karckevski, E; Klausner, JM; Nakache, R; Rudick, V; Weinbroum, AA | 1 |
Andican, G; Benlier, E; Bolayirli, M; Burçak, G; Cetinkale, O; Gelişgen, R; Senyuva, C; Yücel, A | 1 |
Dragun, D; Haller, H; Hoff, U; Luft, FC; Park, JK; Qun, Y; Schneider, W | 1 |
Kim, HC; Park, SB | 1 |
Fukumoto, Y; Iida, H; Maekawa, T; Matsuzaki, M; Murakami, F; Murashige, A; Nakashima, K; Ohashi, S; Seguchi, M; Soejima, Y; Tateishi, A; Umemoto, S; Yamamoto, M; Yamashita, S | 1 |
Armstrong, VW; Braun, F; Niedmann, P; Oellerich, M; Ringe, B; Schütz, E; Shipkova, M; Svinarov, DA; Wieland, E | 1 |
Ishii, T; Kai, T; Kawano, K; Kim, YI; Kobayashi, M; Tatsuma, T | 1 |
Baan, CC; Balk, AH; de Groot-Kruseman, HA; Loonen, EH; Maat, AP; Mol, WM; Niesters, HG; Weimar, W | 1 |
Andoh, T; Bennett, WM; Zager, RA | 1 |
Bohdanecká, M; Bubenícek, P; Kazdová, L; Matl, I; Skibová, J; Táborský, P; Teplan, V; Veselá, J | 1 |
Ahn, HJ; Bang, BK; Han, HJ; Kim, SK; Kim, WY; Kim, YS; Li, C; Moon, IS; Park, JH; Shin, MJ; Yang, CW | 1 |
Boratyńska, M; Szepietowski, T; Szewczyk, Z; Szydłowski, Z | 1 |
Karasawa, Y; Maeba, T; Tanaka, S; Wakabayashi, H | 1 |
Harihara, Y; Idezuki, Y; Sanjo, K | 1 |
Cacciarelli, TV; DiBenedetto, A; Hong, JH; Sommer, BG; Sumrani, N | 1 |
Alivanis, P; Bougioukas, G; Grekas, D; Kalekou, H; Pyrpasopoulos, M; Tourkantonis, A | 1 |
Chen, WJ; Lai, HS; Lee, CS; Lee, PH | 1 |
Fujita, T; Hattori, R; Kinukawa, T; Matsuura, O; Ohshima, S; Ono, Y | 1 |
Häyry, P; Paavonen, T; Yilmaz, S | 1 |
Kim, T; Kishimoto, T; Maekawa, M; Maekawa, T; Nakatani, T; Ohyama, A; Sakamoto, W; Tsujino, T; Yoshimura, R | 1 |
Akizuki, S; Goto, S; Iwao, Y; Kai, T; Kawano, K; Kim, YI; Kobayashi, M; Ono, M | 1 |
Granger, DN; Hunter, J; Kubes, P | 1 |
Becker, HD; de Groot, H; Lauchart, W; Viebahn, R | 1 |
Albert, E; Brockmeyer, C; Felber, E; Feucht, HE; Gokel, MJ; Held, E; Hillebrand, G; Land, W; Nattermann, U; Riethmüller, G | 1 |
Kawashima, H; Kim, T; Kishimoto, T; Kusunose, E; Maekawa, T; Nakatani, T; Ohyama, A; Sakamoto, W; Tsujino, T; Yoshimura, R | 1 |
Cavanel, C; Crafa, F; Gugenheim, J; Lapalus, F; Militerno, G; Mouiel, J; Ouzan, D; Saint-Paul, MC | 1 |
Ding, ZK; Hong, JH; Sumrani, N | 1 |
Bouchier-Hayes, DJ; Broe, PJ; Creagh, TA; Dolan, J; Leader, M; McLean, PA; Murphy, DM; Tormey, W; Walshe, JJ | 2 |
Bernauer, W; Daicker, B; Gratwohl, A; Keller, A | 1 |
Canales-Treviño, ML; Martínez-Palomo, A; Tsutsumi, V | 1 |
7 review(s) available for cyclosporine and Ischemia
Article | Year |
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Cyclophilin-D inhibition in neuroprotection: dawn of a new era of mitochondrial medicine.
Topics: Animals; Arsenicals; Brain Injuries; Calcium; Cyclophilins; Cyclosporine; Enzyme Inhibitors; Humans; Ischemia; Mitochondria; Neuroprotective Agents; Peptidyl-Prolyl Isomerase F | 2013 |
Effects of pituitary adenylate cyclase activating polypeptide in the urinary system, with special emphasis on its protective effects in the kidney.
Topics: Animals; Cisplatin; Cyclosporine; Humans; Hypoxia; Ischemia; Kidney; Kidney Diseases; Oxidative Stress; Pituitary Adenylate Cyclase-Activating Polypeptide; Reperfusion; Urinary Tract | 2012 |
[Ischemic tubulointerstitial injury].
Topics: Acute Disease; Antiphospholipid Syndrome; Arteriosclerosis; Calcineurin Inhibitors; Chronic Disease; Contrast Media; Cyclosporine; Humans; Infarction; Ischemia; Kidney Cortex Necrosis; Kidney Diseases; Renal Artery | 2011 |
Neurotrauma/neurodegeneration and mitochondrial dysfunction.
Topics: Animals; Brain Injuries; Cell Death; Cyclosporine; Humans; Hypoxia; Ischemia; Mitochondria; Nerve Degeneration; Ruthenium Compounds | 2002 |
[Renal insufficiency caused by medicines, diagnostic processes, toxins].
Topics: Acetaminophen; Acute Kidney Injury; Aminoglycosides; Amphotericin B; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Cisplatin; Contrast Media; Cyclosporine; Foscarnet; Humans; Hungary; Ischemia; Kidney; Kidney Function Tests; Pentamidine; Prognosis | 2007 |
Glomerular hemodynamics in acute renal failure.
Topics: Acute Kidney Injury; Animals; Cyclosporine; Glomerular Filtration Rate; Hemodynamics; Humans; Immunosuppressive Agents; Ischemia; Kidney Glomerulus; Renal Blood Flow, Effective | 1997 |
Hemodynamic factors in acute renal failure.
Topics: Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; Contrast Media; Cyclosporine; Hemodynamics; Humans; Ischemia; Kidney | 1997 |
5 trial(s) available for cyclosporine and Ischemia
Article | Year |
---|---|
Verapamil (VP) improves the outcome after renal transplantation (CRT).
Topics: Calcium Channel Blockers; Creatinine; Cyclosporine; Glomerular Filtration Rate; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Ischemia; Kidney Transplantation; Prospective Studies; Retrospective Studies; Time Factors; Tissue and Organ Harvesting; Treatment Outcome; Verapamil | 1992 |
OKT3 prophylaxis improves long-term renal graft survival in high-risk patients as compared to cyclosporine: combined results from the prospective, randomized Belgian and US studies.
Topics: Actuarial Analysis; Azathioprine; Belgium; Cyclosporine; Drug Therapy, Combination; Graft Rejection; Graft Survival; Histocompatibility Testing; HLA-DR Antigens; Humans; Ischemia; Kidney Transplantation; Muromonab-CD3; Organ Preservation; Survival Rate; United States | 1995 |
OKT3 prophylaxis in renal grafts with prolonged cold ischemia times: association with improvement in long-term survival.
Topics: Adult; Cold Temperature; Cyclosporine; Female; Follow-Up Studies; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Incidence; Ischemia; Kidney Transplantation; Male; Muromonab-CD3; Organ Preservation; Prospective Studies; Time Factors | 1996 |
A randomized controlled trial of pentoxifylline for the prevention of delayed graft function in cadaveric kidney graft.
Topics: Adult; Cadaver; Cyclosporine; Double-Blind Method; Endothelium, Vascular; Female; Humans; Immunosuppressive Agents; Incidence; Ischemia; Kidney; Kidney Transplantation; Macrophage Activation; Macrophages; Neutrophil Activation; Neutrophils; Pentoxifylline; Placebos; Reperfusion Injury; Superoxides; Tumor Necrosis Factor-alpha; Vasoconstrictor Agents; Vasodilator Agents | 1997 |
The influence of cold ischemia and donor age on renal allograft outcome in the cyclosporine era.
Topics: Adult; Age Factors; Azathioprine; Cold Temperature; Cyclosporine; Female; Humans; Immunosuppression Therapy; Ischemia; Kidney Transplantation; Male; Middle Aged; Muromonab-CD3; Prednisone; Tissue Donors; Transplantation, Homologous; Treatment Outcome | 1992 |
121 other study(ies) available for cyclosporine and Ischemia
Article | Year |
---|---|
Cyclosporine A loaded brain targeting nanoparticle to treat cerebral ischemia/reperfusion injury in mice.
Topics: Animals; Brain; Brain Ischemia; Cyclosporine; Inflammation; Ischemia; Ischemic Stroke; Mice; Mitochondrial Permeability Transition Pore; Nanoparticles; Reactive Oxygen Species; Reperfusion Injury | 2022 |
Beneficial effects of Cyclosporine A in combination with Nortriptyline on germ cell-specific apoptosis, oxidative stress and epididymal sperm qualities following testicular ischemia/reperfusion in rats: a comparative study.
Topics: Animals; Antioxidants; Apoptosis; Caspase 3; Cyclosporine; Germ Cells; Ischemia; Male; Nortriptyline; Oxidative Stress; Rats; Reperfusion; Reperfusion Injury; Semen; Spermatozoa; Testis | 2022 |
Heat Shock Protein 70 Is Involved in the Efficiency of Preconditioning with Cyclosporine A in Renal Ischemia Reperfusion Injury by Modulating Mitochondrial Functions.
Topics: Animals; Cyclosporine; HSP70 Heat-Shock Proteins; Humans; Hypoxia; Ischemia; Kidney; Mice; Mitochondria; Reperfusion Injury | 2023 |
Effects of cyclosporine on ischemia-reperfusion injuries in rat kidneys. An experimental model.
Topics: Animals; Creatinine; Cyclosporine; Disease Models, Animal; Immunosuppressive Agents; Ischemia; Kidney; Male; Rats; Rats, Wistar; Reperfusion Injury; Sodium; Urea | 2019 |
Cyclosporine A attenuates apoptosis and necrosis after ischemia-reperfusion-induced renal injury in transiently hyperglycemic rats.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Apoptosis; Cell Survival; Cyclosporine; Flow Cytometry; Hyperglycemia; Ischemia; Isoflurane; Kidney; Male; Necrosis; Premedication; Propofol; Protective Agents; Random Allocation; Rats, Wistar; Reperfusion Injury; Reproducibility of Results; Time Factors; Treatment Outcome | 2017 |
Immunosuppression Agent Cyclosporine Reduces Self-Renewal and Vessel Regeneration Potentiation of Human Endothelial Colony Forming Cells.
Topics: Animals; Cell Proliferation; Cells, Cultured; Cyclosporine; Endothelial Progenitor Cells; Hindlimb; Humans; Immunosuppressive Agents; Ischemia; Mesenchymal Stem Cells; Mice; Mice, Inbred BALB C; Neovascularization, Physiologic; NFATC Transcription Factors; Regeneration; Stem Cells | 2019 |
Enhancing Retention of Human Bone Marrow Mesenchymal Stem Cells with Prosurvival Factors Promotes Angiogenesis in a Mouse Model of Limb Ischemia.
Topics: Amino Acid Chloromethyl Ketones; Animals; bcl-X Protein; Bone Marrow Cells; Bone Marrow Transplantation; Cell Line; Collagen; Cyclosporine; Drug Combinations; Enzyme Inhibitors; Extremities; Humans; Insulin-Like Growth Factor I; Ischemia; Laminin; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Inbred NOD; Mice, SCID; Neovascularization, Physiologic; Pinacidil; Proteoglycans; Regenerative Medicine | 2019 |
Inhibition of cyclophilin D by cyclosporin A promotes retinal ganglion cell survival by preventing mitochondrial alteration in ischemic injury.
Topics: Animals; Apoptosis; bcl-Associated Death Protein; bcl-X Protein; Caspase 3; Cell Survival; Cyclophilins; Cyclosporine; Cytoprotection; Disease Models, Animal; DNA-Binding Proteins; DNA, Mitochondrial; Female; High Mobility Group Proteins; Intraocular Pressure; Ischemia; Mice; Mice, Inbred C57BL; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Neuroprotective Agents; Ocular Hypertension; Peptidyl-Prolyl Isomerase F; Phosphorylation; Retinal Diseases; Retinal Ganglion Cells; Time Factors | 2014 |
Mitochondrial Cyclophilin D as a Potential Therapeutic Target for Ischemia-Induced Facial Palsy in Rats.
Topics: Animals; Cyclophilins; Cyclosporine; Drug Delivery Systems; Facial Nerve; Facial Nucleus; Facial Paralysis; Ischemia; Male; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Neural Conduction; Peptidyl-Prolyl Isomerase F; Rats | 2015 |
Cyclosporine action on kidneys of rats submitted to normothermic ischaemia and reperfusion.
Topics: Animals; Biomarkers; Creatinine; Cyclosporine; Disease Models, Animal; Immunosuppressive Agents; Ischemia; Kidney; Male; Nephrectomy; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Time Factors; Urea | 2008 |
Hemolytic uremic syndrome with ischemic glomerulonephropathy and obliterative vasculopathy in a systemic sclerosis patient treated with cyclosporine-A.
Topics: Acute Kidney Injury; Adult; Anemia, Hemolytic; Antirheumatic Agents; Asian People; Creatinine; Cyclosporine; Glomerulonephritis, Membranous; Hemolytic-Uremic Syndrome; Humans; Ischemia; Kidney; Male; Plasma Exchange; Renal Artery; Scleroderma, Systemic; Steroids; Taiwan; Thrombocytopenia; Vasculitis | 2009 |
Ciclosporin does not influence bone marrow-derived cell differentiation to myofibroblasts early after renal ischemia/reperfusion.
Topics: Actins; Animals; Bone Marrow; Cell Differentiation; Cyclosporine; Enzyme Inhibitors; Fibroblasts; Humans; Ischemia; Kidney; Male; Muscle, Smooth; Rats; Rats, Inbred F344; Reperfusion Injury; Stem Cells | 2009 |
Intractable wounds caused by pyoderma gangrenosum in a patient with critical limb ischemia treated with cyclosporine and adjuvant sympathectomy.
Topics: Administration, Oral; Cyclosporine; Dermatologic Agents; Extremities; Humans; Ischemia; Leg Ulcer; Male; Middle Aged; Pyoderma Gangrenosum; Radiography; Sympathectomy; Wound Healing; Wounds and Injuries | 2009 |
Effect of FK506 and cyclosporine A on the expression of BDNF, tyrosine kinase B and p75 neurotrophin receptors in astrocytes exposed to simulated ischemia in vitro.
Topics: Animals; Astrocytes; Brain-Derived Neurotrophic Factor; CREB-Binding Protein; Cyclosporine; Immunosuppressive Agents; Ischemia; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Receptor, Nerve Growth Factor; Receptor, trkB; RNA, Messenger; Tacrolimus | 2009 |
Comparative effects of sirolimus and cyclosporin on conduit arteries endothelial function in kidney recipients.
Topics: Adult; Arteries; Blood Pressure; Cyclosporine; Endothelium, Vascular; Female; Glomerular Filtration Rate; Humans; Immunosuppressive Agents; Ischemia; Kidney; Kidney Transplantation; Male; Middle Aged; Prospective Studies; Sirolimus; Time Factors | 2010 |
Immunosuppression promotes endogenous neural stem and progenitor cell migration and tissue regeneration after ischemic injury.
Topics: Animals; Brain Injuries; Cell Movement; Cerebral Cortex; Cyclosporine; Disease Models, Animal; Glial Fibrillary Acidic Protein; Immunosuppression Therapy; Immunosuppressive Agents; Ischemia; Male; Mice; Mice, Inbred C57BL; Mice, SCID; Motor Activity; Multipotent Stem Cells; Neural Stem Cells; Neurogenesis; Recovery of Function; Regeneration | 2011 |
Immunosuppressant cytoprotection correlates with HMGB1 suppression in primary astrocyte cultures exposed to combined oxygen-glucose deprivation.
Topics: Animals; Astrocytes; Cell Hypoxia; Cells, Cultured; Cyclosporine; Dose-Response Relationship, Drug; Glucose; HMGB1 Protein; Immunosuppressive Agents; Inflammation; Inflammation Mediators; Ischemia; Necrosis; Oxidative Stress; Rats; Rats, Wistar; Sirolimus; Tacrolimus | 2011 |
Uterine allotransplantation in ewes using an aortocava patch.
Topics: Animals; Aorta; Area Under Curve; Cyclosporine; Endometrium; Female; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Ischemia; Magnetic Resonance Imaging; Mycophenolic Acid; Sheep; Time Factors; Transplantation, Homologous; Uterus; Vagina | 2011 |
Multimodal in vivo imaging reveals limited allograft survival, intrapulmonary cell trapping and minimal evidence for ischemia-directed BMSC homing.
Topics: Animals; Cyclosporine; Disease Models, Animal; Genes, Reporter; Graft Survival; Green Fluorescent Proteins; Ischemia; Luciferases; Luminescent Measurements; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Confocal; Transplantation, Homologous | 2012 |
Effects of cyclosporine pretreatment on tissue oxygen levels and cytochrome oxidase in skeletal muscle ischemia and reperfusion.
Topics: Adenosine Triphosphate; Animals; Constriction; Cyclosporine; Edema; Electron Transport Complex IV; Enzyme Inhibitors; Ischemia; Male; Mitochondria, Muscle; Muscle, Skeletal; Oxygen; Phosphocreatine; Rabbits; Random Allocation; Reperfusion Injury; Tissue Survival | 2013 |
Cyclosporine A protects against apoptosis in ischaemic/reperfused rat kidneys.
Topics: Animals; Apoptosis; Cyclosporine; Ischemia; Kidney; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2002 |
Endothelial cell chimerism after renal transplantation in a rat model.
Topics: Animals; Cyclosporine; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Graft Rejection; Immunosuppression Therapy; Ischemia; Kidney; Kidney Transplantation; Male; Necrosis; Rats; Rats, Inbred BN; Rats, Inbred Lew; Renal Circulation; Transplantation Chimera | 2002 |
Preconditioning with cyclosporine A or FK506 differentially regulates mitogen-activated protein kinase expression in rat kidneys with ischemia/reperfusion injury.
Topics: Animals; Cyclosporine; Immunosuppressive Agents; Ischemia; Ischemic Preconditioning; JNK Mitogen-Activated Protein Kinases; Kidney; Male; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tacrolimus | 2003 |
Mitochondrial permeability transition in the switch from necrotic to apoptotic cell death in ischemic rat hepatocytes.
Topics: Animals; Apoptosis; Caspase 3; Caspase Inhibitors; Caspases; Cells, Cultured; Cyclosporine; Energy Metabolism; Enzyme Inhibitors; Fructose; Glycine; Glycolysis; Hepatocytes; In Situ Nick-End Labeling; Ischemia; Liver Circulation; Male; Mitochondria, Liver; Necrosis; Permeability; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Staining and Labeling | 2003 |
Delayed graft function after renal transplantation from a non-heart-beating donors.
Topics: Adult; Child; Cyclosporine; Drug Therapy, Combination; Graft Survival; Heart Arrest; Histocompatibility Testing; HLA-DR Antigens; Humans; Immunosuppressive Agents; Ischemia; Kidney; Kidney Transplantation; Middle Aged; Organ Preservation; Postoperative Complications; Renal Dialysis; Tacrolimus; Time Factors; Tissue Donors | 2003 |
A new model of chronic cyclosporine nephrotoxicity for comparative morphologic and histologic studies.
Topics: Animals; Cyclosporine; Disease Models, Animal; Immunosuppressive Agents; Ischemia; Kidney; Male; Rats; Rats, Sprague-Dawley | 2003 |
Simvastatin attenuates renal ischemia/reperfusion injury in rats administered cyclosporine A.
Topics: Analysis of Variance; Animals; Body Weight; Cyclosporine; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Hemodynamics; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunosuppressive Agents; Iohexol; Ischemia; Kidney; Male; Microcirculation; Nitric Oxide; Organ Size; Rats; Rats, Wistar; Reperfusion Injury; Simvastatin; Time Factors; Vasoconstrictor Agents | 2003 |
Rapamycin preserves renal function compared with cyclosporine A after ischemia/reperfusion injury.
Topics: Animals; Calcineurin; Cyclosporine; Glomerular Filtration Rate; Immunosuppressive Agents; Ischemia; Kidney; Kidney Diseases; Kidney Transplantation; Male; Nephrectomy; Postoperative Complications; Rats; Rats, Wistar; Reperfusion Injury; Sirolimus; Tissue and Organ Procurement | 2003 |
Effect of cyclosporin A upon the function of ischemically damaged renal autografts in the dog.
Topics: Animals; Cyclosporine; Dogs; Graft Survival; Immunosuppressive Agents; Ischemia; Kidney; Kidney Transplantation; Time Factors; Transplantation, Autologous | 1980 |
Cyclosporine A sensitizes the kidney to tubulointerstitial fibrosis induced by renal warm ischemia.
Topics: Animals; Collagen Type III; Cyclosporine; Fibrosis; Hot Temperature; Immunosuppressive Agents; Ischemia; Kidney; Kidney Transplantation; Male; Matrix Metalloproteinase 2; Nephritis, Interstitial; Rats; Rats, Sprague-Dawley; RNA, Messenger; Severity of Illness Index; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2004 |
Augmentation of ischemia/reperfusion injury to endothelial cells by cyclosporin A.
Topics: Analysis of Variance; Animals; Apoptosis; Calcineurin Inhibitors; Cell Count; Cell Line, Transformed; Cell Survival; Cells, Cultured; Coloring Agents; Cyclosporine; Endothelial Cells; Graft Rejection; Immunosuppressive Agents; Ischemia; Mice; Necrosis; Reperfusion Injury; Tacrolimus; Time Factors; Trypan Blue | 2004 |
Role of the permeability transition pore in cytochrome C release from mitochondria during ischemia-reperfusion in rat liver.
Topics: Animals; Caspases; Cyclosporine; Cytochromes c; Drug Interactions; Hypoxia; Ischemia; Liver Diseases; Mitochondria; Mitochondria, Liver; Permeability; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Reperfusion | 2004 |
The long-term outcome of tacrolimus in cadaveric kidney transplantation from non-heart beating donors.
Topics: Adult; Cadaver; Cyclosporine; Female; Follow-Up Studies; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Ischemia; Kidney; Kidney Failure, Chronic; Kidney Transplantation; Kidney Tubular Necrosis, Acute; Longitudinal Studies; Male; Methylprednisolone; Survival Rate; Tacrolimus; Tissue and Organ Harvesting; Tissue Donors; Treatment Outcome | 2005 |
A comparison of long-term graft survival rates between the first and second donor kidney transplanted--the effect of a longer cold ischaemic time for the second kidney.
Topics: Adult; Cold Temperature; Cyclosporine; Female; Graft Survival; Humans; Immunosuppressive Agents; Ischemia; Kidney Transplantation; Male; Middle Aged; Organ Preservation; Risk Factors; Time Factors; Tissue Donors; Treatment Outcome | 2005 |
A comparison of tacrolimus and cyclosporine in liver transplantation: effects on renal function and cardiovascular risk status.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Blood Pressure; Cardiovascular Diseases; Cardiovascular System; Child; Child, Preschool; Cholesterol; Cyclosporine; Female; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Infant; Infant, Newborn; Ischemia; Kidney; Lipid Metabolism; Liver Diseases; Liver Transplantation; Male; Middle Aged; Retrospective Studies; Tacrolimus; Time Factors; Treatment Outcome; Triglycerides | 2005 |
Cyclosporin A but not FK-506 protects against dopamine-induced apoptosis in the stunned heart.
Topics: Animals; Apoptosis; Cyclosporine; Disease Models, Animal; Dopamine; Immunosuppressive Agents; Ischemia; Myocardial Stunning; Myocardium; Oxygen Consumption; Rabbits; Reperfusion; Tacrolimus | 2005 |
Ciliary tissue transplantation in the rabbit.
Topics: Animals; Ciliary Body; Cyclosporine; Female; Fibrosis; Graft Survival; Immunosuppressive Agents; Ischemia; Perfusion; Rabbits; Reperfusion; Time Factors; Transplantation, Homologous; Vascular Endothelial Growth Factor A | 2006 |
Preconditioning of the distal tubular epithelium of the human kidney precedes nephrocalcinosis.
Topics: Cell Division; Chronic Disease; Crystallization; Cyclosporine; Graft Rejection; Humans; Hyaluronic Acid; Immunosuppressive Agents; Infant, Newborn; Infant, Premature; Ischemia; Kidney Transplantation; Kidney Tubules, Distal; Nephrocalcinosis; Nephrons; Osteopontin; Sialoglycoproteins | 2005 |
Cyclosporine increases ischemia-induced endothelial progenitor cell mobilization through manipulation of the CD26 system.
Topics: Animals; Bone Marrow Transplantation; Cells, Cultured; Cyclosporine; Cytokines; Dipeptidyl Peptidase 4; Endothelial Cells; Flow Cytometry; Hindlimb; Humans; Immunosuppressive Agents; Ischemia; Male; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Myocytes, Smooth Muscle; Neovascularization, Physiologic; Reverse Transcriptase Polymerase Chain Reaction; Stem Cells | 2008 |
Effective prevention of ischemic injury of the dearterialized canine liver by FK506 pretreatment.
Topics: Adenosine Triphosphate; Alanine Transaminase; Animals; Aspartate Aminotransferases; Cyclosporine; Dogs; Female; Ischemia; L-Lactate Dehydrogenase; Liver; Male; Reperfusion Injury; Tacrolimus | 1993 |
Microvascular transplantation of physeal allografts.
Topics: Analysis of Variance; Anastomosis, Surgical; Animals; Cyclosporine; Follow-Up Studies; Growth Plate; Hypertrophy; Immunosuppression Therapy; Ischemia; Microsurgery; Polymorphism, Restriction Fragment Length; Rabbits; Radiography; Radionuclide Imaging; Technetium Tc 99m Medronate; Tibia; Transplantation, Autologous; Transplantation, Homologous | 1995 |
Increased efficacy of CSA following rearterialization in the rat OLTX model.
Topics: Animals; Cyclosporine; Immunosuppression Therapy; Immunosuppressive Agents; Ischemia; Liver Circulation; Liver Transplantation; Male; Rats; Rats, Inbred Lew; Survival Analysis | 1995 |
Relative importance of ischemic injury and immunological injury on the development of transplant arteriosclerosis in rabbit aortic allografts.
Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Body Weight; Cholesterol; Cyclosporine; Immunosuppressive Agents; Ischemia; Lipoproteins; Male; Rabbits; T-Lymphocytes; Time Factors; Transplantation, Homologous; Tunica Intima | 1995 |
Nonimmunologic causes of late renal graft loss.
Topics: Adult; Cyclosporine; Graft Rejection; Hemodynamics; Humans; Hypertension; Ischemia; Kidney; Kidney Failure, Chronic; Kidney Transplantation; Lipids; Male | 1995 |
Neutrophil infiltration as an important factor in liver ischemia and reperfusion injury. Modulating effects of FK506 and cyclosporine.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cyclosporine; Ischemia; L-Lactate Dehydrogenase; Liver; Male; Malondialdehyde; Microscopy, Electron; Neutrophils; Peroxidase; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Survival Analysis; Tacrolimus | 1993 |
Effect of allopurinol, folinic acid, SOD and cyclosporine A on ischemic liver regeneration.
Topics: Allopurinol; Animals; Cyclosporine; Ischemia; Leucovorin; Liver; Liver Regeneration; Male; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 1995 |
[Prevention of ischemic injury in hepatocellular transplant in the rat].
Topics: Animals; Antioxidants; Cell Transplantation; Cyclosporine; Ischemia; Liver; Male; Rats; Rats, Inbred F344 | 1994 |
Antigen-independent events mimic characteristic changes of chronic allograft rejection.
Topics: Animals; Chronic Disease; Cyclosporine; Cytokines; Gene Expression; Graft Rejection; Ischemia; Isoantigens; Kidney Transplantation; Male; Models, Immunological; Rats; Rats, Inbred F344; Rats, Inbred Lew; Reperfusion Injury; T-Lymphocytes; Transplantation, Homologous; Transplantation, Isogeneic | 1995 |
Early prognosis of 263 renal allografts harvested from non-heart-beating cadavers using an in situ cooling technique.
Topics: Adult; Age Factors; Azathioprine; Cadaver; Cyclosporine; Humans; Ischemia; Kidney; Kidney Transplantation; Middle Aged; Organ Preservation; Prognosis; Retrospective Studies; Temperature; Time Factors; Tissue Donors | 1995 |
Deleterious effect of cyclosporines on the ischemic kidney in the rat and protection by the calcium antagonist verapamil.
Topics: Animals; Cyclosporine; Cyclosporins; Immunosuppressive Agents; Ischemia; Kidney; Male; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Renal Circulation; Verapamil | 1994 |
Deleterious effect of cyclosporins on the ischemic kidney in the rat and the protection by the calcium antagonist verapamil.
Topics: Animals; Creatinine; Cyclosporine; Cyclosporins; Ischemia; Kidney; Kidney Diseases; Male; Nephrectomy; Rats; Rats, Sprague-Dawley; Renal Circulation; Verapamil | 1994 |
Increased platelet-derived growth factor in the kidneys of cyclosporin-treated rats.
Topics: Animals; Chronic Disease; Cyclosporine; Immunoenzyme Techniques; Injections, Intraperitoneal; Ischemia; Kidney; Male; Platelet-Derived Growth Factor; Rats; Rats, Sprague-Dawley | 1994 |
Ischemic injury and experimental transplantation atherosclerosis.
Topics: Animals; Aorta, Abdominal; Aorta, Thoracic; Arteriosclerosis; Cholesterol; Cyclosporine; Ischemia; Rabbits; Reperfusion Injury; Transplantation, Homologous; Vascular Surgical Procedures | 1994 |
Serum erythropoietin levels after renal transplantation.
Topics: Cyclosporine; Drug Therapy, Combination; Erythropoietin; Graft Rejection; Humans; Immunosuppressive Agents; Ischemia; Kidney; Kidney Transplantation; Organ Preservation; Postoperative Period | 1994 |
Attenuation of cold ischemic liver injury by cyclosporine in association with endotoxemia and chemokine release.
Topics: Animals; Cold Temperature; Cyclosporine; Endotoxins; Graft Survival; Ischemia; Kinetics; Liver; Liver Circulation; Liver Transplantation; Male; Organ Preservation; Rats; Rats, Wistar; Reperfusion Injury; Time Factors; Tumor Necrosis Factor-alpha | 1994 |
Comparison of University of Wisconsin solution and University of Rochester (modified Collins) solution for renal preservation in renal transplantation.
Topics: Adenosine; Allopurinol; Cadaver; Cyclosporine; Glutathione; Graft Survival; Humans; Hypertonic Solutions; Insulin; Ischemia; Kidney; Kidney Transplantation; Kidney Tubular Necrosis, Acute; Organ Preservation; Organ Preservation Solutions; Raffinose; Time Factors; Tissue Donors | 1994 |
Intrahepatic neutrophil accumulation in ischemia/reperfusion injury of pig liver.
Topics: Animals; Biopsy; Cyclosporine; Female; Ischemia; Liver; Liver Circulation; Male; Neutrophils; Reference Values; Regional Blood Flow; Reperfusion Injury; Swine | 1994 |
Suppression of superoxide production from polymorphonuclear leukocytes by cyclosporine in ischemia-reperfusion of the liver.
Topics: Animals; Cyclosporine; Female; Ischemia; Kinetics; Liver; Liver Function Tests; Microcirculation; Neutrophils; Rats; Rats, Sprague-Dawley; Reperfusion; Superoxides; Time Factors | 1994 |
[Comparison of the effects of 2 preparations of cyclosporin A-- Consupren and Sandimmune--from the aspect of functional and morphologic changes in rats with renal ischemia].
Topics: Animals; Cyclosporine; Ischemia; Kidney; Male; Rats; Rats, Wistar | 1994 |
[Effect of recombinant atrial natriuretic peptide (r-ANP) on ischemic and cyclosporine-induced kidney damage in rats].
Topics: Animals; Atrial Natriuretic Factor; Cyclosporine; Ischemia; Kidney; Male; Rats; Rats, Inbred F344; Recombinant Proteins | 1994 |
Pharmacological manipulation of acute cyclosporin ischemic renal injury with trimetazidine.
Topics: Animals; Cyclosporine; Dogs; Ischemia; Kidney; Renal Insufficiency; Trimetazidine | 1993 |
Evaluation of animal models of chronic vascular rejection.
Topics: Animals; Arteriosclerosis; Atrophy; Chronic Disease; Cyclosporine; Disease Models, Animal; Fibrosis; Graft Rejection; Hyperplasia; Ischemia; Kidney Transplantation; Rats; Rats, Inbred F344; Rats, Inbred Lew; Rats, Inbred Strains; Rats, Wistar; Renal Circulation | 1993 |
[The hepatotrophic action of cyclosporin A in a model of hepatic ischemia in the rat].
Topics: Animals; Cyclosporine; Disease Models, Animal; DNA; Hepatectomy; Ischemia; Liver; Liver Regeneration; Male; Rats; Rats, Sprague-Dawley | 1993 |
Morphology of ischemic acute renal failure, normal function, and cyclosporine toxicity in cyclosporine-treated renal allograft recipients.
Topics: Adult; Aged; Cell Membrane; Cyclosporine; Female; Humans; Ischemia; Kidney; Kidney Failure, Chronic; Kidney Transplantation; Kidney Tubules; Male; Microscopy, Electron; Middle Aged; Necrosis; Postoperative Care; Reference Values; Renal Circulation; Transplantation, Homologous | 1993 |
Influence of warm ischemia on cyclosporine nephrotoxicity in renal isografts in rats.
Topics: Animals; Creatinine; Cyclosporine; Female; Ischemia; Kidney Function Tests; Kidney Transplantation; Organ Preservation; Rats; Rats, Inbred Lew; Temperature; Time Factors; Transplantation, Isogeneic | 1993 |
Role of endothelin in renal function and dysfunction.
Topics: Acute Kidney Injury; Animals; Contrast Media; Cyclosporine; Endothelins; Ischemia; Kidney; Kidney Diseases; Rats; Renal Circulation; Vasoconstriction | 1996 |
Cyclosporine nephrotoxicity in the ischemic kidney and the protective effect of pentoxifylline--a study in the rat.
Topics: Animals; Calcinosis; Creatinine; Cyclosporine; Ischemia; Kidney; Kidney Diseases; Kidney Tubules; Ligation; Microcirculation; Pentoxifylline; Prostaglandins; Rats; Rats, Sprague-Dawley; Thromboxane A2; Vacuoles; Vasoconstriction; Vasodilator Agents | 1996 |
Neutrophil-mediated injury in ischemic skin flaps: amelioration of ischemic injury by cyclosporine in the rat.
Topics: Animals; Antifungal Agents; Cyclosporine; Dermatologic Surgical Procedures; Graft Survival; Ischemia; Male; Neutrophils; Rats; Rats, Wistar; Skin; Surgical Flaps | 1996 |
Comparison of two antilymphocyte globulins replacing cyclosporin A after first kidney allotransplantation and prolonged graft ischemia.
Topics: Antilymphocyte Serum; Cyclosporine; Humans; Ischemia; Kidney; Kidney Transplantation; Pancreas Transplantation; Prednisone; Retrospective Studies | 1996 |
Beneficial effects of cyclosporine and rapamycin in small bowel ischemic injury.
Topics: alpha-Glucosidases; Animals; Cyclosporine; Immunosuppressive Agents; Intestinal Mucosa; Intestine, Small; Ischemia; Male; Polyenes; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Sirolimus; Tumor Necrosis Factor-alpha; Xanthine Oxidase | 1996 |
Fructose-1,6-diphosphate: potential protection in cyclosporine-induced renal impairment.
Topics: Animals; Cyclosporine; Fructosediphosphates; Glomerular Filtration Rate; Immunologic Factors; Ischemia; Kidney; Male; Rats; Rats, Wistar; Renal Circulation; Vascular Resistance | 1996 |
Active secretion of drugs from the small intestinal epithelium in rats by P-glycoprotein functioning as an absorption barrier.
Topics: Adenosine Triphosphate; Adrenergic beta-Antagonists; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Cyclosporine; Drug Resistance; Epithelium; Humans; Intestinal Absorption; Intestine, Small; Ischemia; Male; Rats; Rats, Wistar; Vinblastine | 1996 |
Cholic acid synthesis is reduced in pediatric liver recipients during graft dysfunction due to ischemic injury and allograft rejection.
Topics: Adolescent; Bile Acids and Salts; Child; Child, Preschool; Cholic Acid; Cholic Acids; Chromatography, High Pressure Liquid; Cyclosporine; Female; Graft Rejection; Humans; Immunosuppressive Agents; Infant; Ischemia; Liver; Liver Transplantation; Male; Postoperative Complications; Prospective Studies; Tacrolimus | 1997 |
[Nephrotoxicity of Sandimmune and Consupren in an experiment].
Topics: Animals; Cyclosporine; Immunosuppressive Agents; Ischemia; Kidney; Male; Rats; Rats, Wistar | 1995 |
The effect of calcium on hypothermia-facilitated resuscitation of warm ischemic kidney tissue slices: a role for the mitochondrial permeability transition pore?
Topics: Adenosine Triphosphate; Aerobiosis; Animals; Calcium; Cold Temperature; Cyclosporine; Fatty Acids, Nonesterified; In Vitro Techniques; Ischemia; Kidney Cortex; Kidney Transplantation; Male; Mitochondria; Permeability; Quinacrine; Rabbits; Reperfusion Injury; Solutions; Tissue Preservation | 1998 |
Accelerated apoptosis characterizes cyclosporine-associated interstitial fibrosis.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Apoptosis; Arginine; Biotin; Cyclosporine; Deoxyuracil Nucleotides; DNA Fragmentation; Enzyme Inhibitors; Fibrosis; Hydralazine; Immunosuppressive Agents; Ischemia; Kidney; Losartan; Macrophages; Male; Nephritis, Interstitial; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Staining and Labeling | 1998 |
Immunosuppressants enhance superoxide radical/nitric oxide-dependent dexamethasone suppression of ischemic paw edema in mice.
Topics: Animals; Anti-Inflammatory Agents; Cyclosporine; Dexamethasone; Drug Interactions; Edema; Hindlimb; Immunosuppressive Agents; Ischemia; Male; Mice; Nitric Oxide; Superoxides; Tacrolimus | 1998 |
Protection by cyclosporine A against normothermic liver ischemia-reperfusion in pigs.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cyclosporine; Dose-Response Relationship, Drug; Hepatic Artery; Immunosuppressive Agents; Ischemia; Liver; Liver Circulation; Reference Values; Regional Blood Flow; Reperfusion Injury; Temperature | 1998 |
Successful gene transfer to the porcine liver in vivo with an adenoviral vector.
Topics: Adenoviridae; Animals; beta-Galactosidase; Cold Temperature; Cyclophosphamide; Cyclosporine; Female; Gene Transfer Techniques; Genetic Vectors; Hepatic Artery; Immunosuppressive Agents; Injections; Ischemia; Liver; Polymerase Chain Reaction; Prednisolone; Swine | 1998 |
Effects of cyclosporin A and ibuprofen on liver ischemia-reperfusion injury in the rat.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspartate Aminotransferases; Cyclooxygenase Inhibitors; Cyclosporine; Ibuprofen; Immunosuppressive Agents; Ischemia; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 1998 |
Synergistic mechanisms of alloantigen-dependent and independent events in chronic graft rejection.
Topics: Animals; Chronic Disease; Cyclosporine; Graft Rejection; Heart Transplantation; Immune Tolerance; Immunosuppression Therapy; Immunosuppressive Agents; Ischemia; Isoantigens; Kidney; Kidney Transplantation; Organ Preservation; Rats; Rats, Inbred F344; Rats, Inbred Lew; Transplantation, Homologous | 1998 |
Mitochondrial function as a determinant of recovery or death in cell response to injury.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Calcium; Cell Membrane Permeability; Cells, Cultured; Cyclosporine; Heart; Ion Channels; Ischemia; Mitochondria; Myocardium; Oxidative Phosphorylation; Reperfusion Injury | 1998 |
Mitochondrial permeability transition during hypothermic to normothermic reperfusion in rat liver demonstrated by the protective effect of cyclosporin A.
Topics: Animals; Cyclosporine; Energy Metabolism; Hypothermia; In Vitro Techniques; Intracellular Membranes; Ischemia; Liver; Magnetic Resonance Spectroscopy; Male; Mitochondria, Liver; Oxidation-Reduction; Perfusion; Permeability; Phosphorus Isotopes; Phosphorylation; Protons; Rats; Rats, Wistar; Reperfusion | 1998 |
Cadaveric renal transplantations with prolonged warm ischemic times greater than 30 minutes.
Topics: Adult; Cadaver; Creatinine; Cyclosporine; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Ischemia; Kidney; Kidney Transplantation; Male; Middle Aged; Organ Preservation; Renal Dialysis; Retrospective Studies; Temperature; Time Factors; Tissue Donors | 1998 |
Cyclosporin impairs bile duct arterial supply in ischemic livers.
Topics: Animals; Aorta; Arteries; Bile Ducts; Blood Flow Velocity; Cyclosporine; Immunosuppressive Agents; In Vitro Techniques; Ischemia; Liver; Microspheres; Perfusion; Portal System; Rats | 1998 |
Suppressed endothelin-1 production by FK506 and cyclosporin A in ischemia/reperfusion of rat small intestine.
Topics: Animals; Azepines; Blood Pressure; Cyclosporine; Endothelin Receptor Antagonists; Endothelin-1; Hypotension; Immunosuppressive Agents; Intestine, Small; Ischemia; Male; Microcirculation; Oligopeptides; Portal System; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptors, Endothelin; Reperfusion Injury; Survival Rate; Tacrolimus; Time Factors | 1999 |
Exploitation of the continuum between early ischemia/reperfusion injury and host alloresponsiveness: indefinite kidney allograft survival by treatment with a soluble P-selectin ligand and low-dose cyclosporine in combination.
Topics: Animals; Chemokine CCL2; Cyclosporine; Dose-Response Relationship, Immunologic; Drug Therapy, Combination; Graft Survival; Immunohistochemistry; Immunosuppressive Agents; Intercellular Adhesion Molecule-1; Ischemia; Isoantibodies; Kidney; Kidney Transplantation; Male; Membrane Glycoproteins; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Messenger | 1999 |
The effects of early and delayed immunosuppression in experimental tracheal transplantation with omentopexy.
Topics: Animals; Cyclosporine; Graft Rejection; Immunosuppression Therapy; Immunosuppressive Agents; Ischemia; Omentum; Rabbits; Time Factors; Trachea | 1999 |
Prolonged cold ischemia, late graft dysfunction, and cyclosporine in renal transplantation.
Topics: Animals; Cold Temperature; Cryopreservation; Cyclosporine; Immunosuppressive Agents; Ischemia; Kidney; Kidney Transplantation; Organ Preservation; Proteinuria; Rats; Tissue Donors | 1999 |
Late graft dysfunction after prolonged cold ischemia of the donor kidney: inhibition by cyclosporine.
Topics: Adenosine; Allopurinol; Animals; Cryopreservation; Cyclosporine; Glutathione; Graft Rejection; Immunohistochemistry; Immunosuppressive Agents; Insulin; Ischemia; Kidney; Kidney Transplantation; Male; Organ Preservation; Organ Preservation Solutions; Raffinose; Rats; Rats, Inbred BN; Rats, Wistar; Time Factors; Transplantation, Homologous; Transplantation, Isogeneic | 1999 |
Cyclosporin A-sensitive changes in mitochondrial glutathione are an early response to intrastiatal NMDA or forebrain ischemia in rats.
Topics: Animals; Corpus Striatum; Cyclosporine; Glutathione; Injections; Ischemia; Male; Mitochondria; N-Methylaspartate; Prosencephalon; Rats; Rats, Wistar | 1999 |
Cumulative damaging effect of liver hypoperfusion and cyclosporine a on the peribiliary capillary plexus: a study in an isolated dually perfused rat model.
Topics: Animals; Bile Ducts; Capillaries; Cyclosporine; Immunosuppressive Agents; In Vitro Techniques; Ischemia; L-Lactate Dehydrogenase; Lactates; Liver; Liver Circulation; Male; Microspheres; Oxygen Consumption; Perfusion; Pyruvates; Rats; Rats, Wistar; Vascular Resistance | 1999 |
Secondary venous ischemic injury associated with neutrophil infiltration and lipid peroxidation: amelioration of injury by cyclosporin A in a rat inguinal island flap.
Topics: Animals; Cyclosporine; Immunosuppressive Agents; Ischemia; Lipid Peroxidation; Male; Neutrophil Infiltration; Rats; Rats, Wistar; Surgical Flaps | 2000 |
Ischemia-reperfusion injury in renal transplantation is independent of the immunologic background.
Topics: Animals; Cell Adhesion Molecules; Cyclosporine; Graft Rejection; Immunosuppressive Agents; Integrin alpha4beta1; Integrins; Ischemia; Kidney; Kidney Transplantation; Lymphocyte Function-Associated Antigen-1; Male; Necrosis; Nephritis; Rats; Rats, Inbred F344; Rats, Inbred Lew; Receptors, Lymphocyte Homing; Renal Circulation; Reperfusion Injury; Selectins; Transplantation, Homologous; Transplantation, Isogeneic | 2000 |
Mycophenolate mofetil-induced ischemic colitis.
Topics: Colitis; Colon; Creatinine; Cyclosporine; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Ischemia; Kidney Transplantation; Middle Aged; Muromonab-CD3; Mycophenolic Acid; Tacrolimus | 2000 |
Mixed connective tissue disease with multiple organ damage: successful treatment with plasmapheresis.
Topics: Acidosis; Adult; Autoantigens; Autoimmune Diseases; Bronchitis; Calcinosis; Combined Modality Therapy; Cyclosporine; Disseminated Intravascular Coagulation; Female; Hemorrhage; Humans; Immunosuppressive Agents; Ischemia; Methylprednisolone; Mixed Connective Tissue Disease; Multiple Organ Failure; Plasmapheresis; Ribonucleoprotein, U1 Small Nuclear; Vasoconstriction; Viscera | 2000 |
Preliminary report on the effect of xenoperfusion with human blood on cyclosporin A metabolism and cytochrome-P-4503A4-mRNA expression in a pig liver perfusion model.
Topics: Animals; Aspartate Aminotransferases; Chromatography, High Pressure Liquid; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Glutamate Dehydrogenase; Humans; Immunosuppressive Agents; Interleukin-6; Ischemia; Liver; Mixed Function Oxygenases; Perfusion; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Swine; Time Factors | 2001 |
Immunodepressants ameliorate normothermic ischemia injury to the rat liver by down-regulating tumor necrosis factor, not by alleviation of lipid peroxidative injury.
Topics: Alanine Transaminase; Animals; Azathioprine; Cyclosporine; Female; Immunosuppressive Agents; Ischemia; Lipid Peroxidation; Liver; Phosphatidylcholines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tacrolimus; Temperature; Time Factors; Tumor Necrosis Factor-alpha | 1994 |
Failure to down-regulate intragraft cytokine mRNA expression shortly after clinical heart transplantation is associated with high incidence of acute rejection.
Topics: Acute Disease; Biopsy; Chemokine CCL2; Cyclosporine; Cytokines; Endocardium; Fibroblast Growth Factor 2; Gene Expression Regulation; Graft Rejection; Heart Transplantation; Humans; Immunosuppressive Agents; Incidence; Ischemia; Myocardium; RNA, Messenger; Vascular Diseases | 2001 |
Renal cholesterol accumulation: a durable response after acute and subacute renal insults.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Cholesterol; Cholesterol Esters; Cyclosporine; Dehydration; Glomerulonephritis; Glycerol; Ischemia; Kidney; Kidney Cortex; Kidney Medulla; Kidney Tubules; Male; Mice; Nephritis; Rats; Rats, Sprague-Dawley; Reperfusion; Tacrolimus | 2001 |
[Nitric oxide (NO) in a model of renal ischemia and cyclosporine toxicity].
Topics: Animals; Arginine; Cyclosporine; Immunosuppressive Agents; Ischemia; Kidney; Male; Nitric Oxide; Rats; Rats, Wistar; Vasodilator Agents | 2001 |
Pharmacological preconditioning with low-dose cyclosporine or FK506 reduces subsequent ischemia/reperfusion injury in rat kidney.
Topics: Animals; Apoptosis; Blood Urea Nitrogen; Caspases; Creatinine; Cyclosporine; Dose-Response Relationship, Drug; Gene Expression; HSP70 Heat-Shock Proteins; Immunosuppressive Agents; Interleukin-1; Ischemia; Kidney Transplantation; Male; Rats; Rats, Sprague-Dawley; Renal Circulation; Reperfusion Injury; Tacrolimus; Transplantation Conditioning; Tumor Necrosis Factor-alpha | 2001 |
Antilymphocyte globulin with a small dose of cyclosporine A and prednisone as the induction of immunosuppression in renal allograft recipients.
Topics: Acute Disease; Acute Kidney Injury; Adult; Antilymphocyte Serum; Azathioprine; Cyclosporine; Drug Therapy, Combination; Female; Graft Rejection; Humans; Incidence; Infections; Ischemia; Kidney; Kidney Transplantation; Male; Middle Aged; Muromonab-CD3; Phlebitis; Postoperative Complications; Prednisone; Survival Rate; Thrombocytopenia; Transplantation, Homologous | 1992 |
Effect of FK 506 and cyclosporine A on hepatic energy status in the rat after warm ischemia, as monitored by 31P nuclear magnetic resonance spectroscopy in vivo.
Topics: Adenosine Triphosphate; Animals; Cyclosporine; Energy Metabolism; Ischemia; Kinetics; Liver; Magnetic Resonance Spectroscopy; Male; Phosphates; Phosphorus; Rats; Rats, Sprague-Dawley; Reperfusion; Tacrolimus; Temperature; Time Factors | 1992 |
Cyclosporine hepatotoxicity and cold ischemia liver damage.
Topics: Animals; Bilirubin; Cold Temperature; Cyclosporine; Ischemia; Liver; Liver Circulation; Liver Transplantation; Male; Rats; Rats, Inbred Lew; Transplantation, Isogeneic | 1992 |
Reduction of CyA nephrotoxicity by nifedipine during and after experimental in situ renal preservation.
Topics: Animals; Cyclosporine; Dogs; Drug Interactions; Ischemia; Kidney; Nifedipine; Organ Preservation; Perfusion; Time Factors; Vasoconstriction | 1992 |
The effect of cyclosporine on warm ischemic kidneys in rats.
Topics: Animals; Cyclosporine; Dose-Response Relationship, Drug; Ischemia; Kidney; Kidney Transplantation; Rats; Rats, Inbred Lew; Temperature; Time Factors | 1992 |
Outcome of kidney transplantation from non-heart-beating donors: comparison with heart-beating donors.
Topics: Cadaver; Creatinine; Cyclosporine; Death; Graft Survival; Humans; Immunosuppression Therapy; Ischemia; Kidney Transplantation; Survival Analysis; Time Factors; Tissue Donors | 1992 |
Chronic rejection of rat renal allografts. II. The impact of prolonged ischemia time on transplant histology.
Topics: Animals; Creatinine; Cyclosporine; Graft Rejection; Ischemia; Kidney; Kidney Transplantation; Male; Rats; Rats, Inbred Strains; Time Factors; Transplantation, Homologous | 1992 |
Effect of ciclosporin on cardiac output and regional blood flow in rats: ciclosporin-induced nephropathy and its prevention with calcium channel blocker.
Topics: Animals; Cardiac Output; Cyclosporine; Hemodynamics; Ischemia; Kidney; Kidney Diseases; Male; Rats; Rats, Inbred Strains; Regional Blood Flow; Renal Circulation; Verapamil | 1992 |
Protection of pig liver against normothermic ischemia by immunosuppressants cyclosporine and azathioprine.
Topics: Animals; Azathioprine; Cyclosporine; Female; Ischemia; Liver; Male; Swine; Tissue Preservation | 1992 |
Effects of cyclosporin A and FK506 on ischemia/reperfusion-induced neutrophil infiltration in the cat.
Topics: Animals; Cats; Cyclosporine; In Vitro Techniques; Intestine, Small; Ischemia; Leukocyte Count; Leukotriene B4; Neutrophils; Peroxidase; Reperfusion Injury; Tacrolimus | 1991 |
Hypoxic and reoxygenation injury in human and rat hepatocytes--influence of FK 506 and cyclosporine.
Topics: Animals; Cell Hypoxia; Cell Survival; Cells, Cultured; Cyclosporine; Humans; Ischemia; Liver; Rats; Tacrolimus; Tissue Preservation | 1991 |
Vascular deposition of complement-split products in kidney allografts with cell-mediated rejection.
Topics: Antibodies, Monoclonal; Biopsy; Capillaries; Complement Activation; Complement C4; Complement C4b; Cyclosporine; Glomerulonephritis; Graft Rejection; Humans; Immunity, Cellular; Immunoenzyme Techniques; Immunoglobulin M; Ischemia; Kidney; Kidney Transplantation; Peptide Fragments; Transplantation, Homologous | 1991 |
[Effects of verapamil on cyclosporine. A (CsA)-induced nephropathy in ischemic kidney model in rats: changes in systemic hemodynamics and hepatic and renal microsomal cytochrome P-450].
Topics: Animals; Cyclosporine; Cytochrome P-450 Enzyme System; Disease Models, Animal; Enzyme Induction; Hemodynamics; Ischemia; Kidney; Kidney Diseases; Microsomes; Microsomes, Liver; Nephrectomy; Rats; Rats, Inbred Strains; Renal Circulation; Verapamil | 1991 |
Protective effects of prostaglandin E1 on normothermic liver ischemia.
Topics: Alprostadil; Animals; Cyclosporine; Ischemia; Kupffer Cells; Liver; Male; Rats; Rats, Inbred Lew; Survival Rate | 1991 |
Effect of timing of cyclosporine administration on recovery from renal ischemia in rats.
Topics: Animals; Creatinine; Cyclosporine; Ischemia; Kidney; Kidney Diseases; Male; Rats; Rats, Inbred Strains; Time Factors | 1991 |
A canine model of cyclosporine enhanced ischemic renal injury.
Topics: Animals; Cyclosporine; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Ischemia; Kidney; Nephrectomy; Time Factors | 1991 |
Prevention of cyclosporine enhanced ischaemic renal injury using induced hypothermia.
Topics: Animals; Cyclosporine; Disease Models, Animal; Dogs; Hypothermia, Induced; Ischemia; Kidney; Time Factors | 1991 |
Microvasculopathy in the ocular fundus after bone marrow transplantation.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Child; Cyclosporine; Female; Fundus Oculi; Graft vs Host Disease; Humans; Ischemia; Male; Middle Aged; Optic Disk; Prospective Studies; Retinal Diseases; Retinal Vessels; Risk Factors; Whole-Body Irradiation | 1991 |
[Role of macrophages and T-lymphocytes: resistance of guinea pigs to amebic liver infection].
Topics: Animals; Cyclosporine; Entamoeba histolytica; Guinea Pigs; Immunity, Cellular; Immunity, Innate; Inflammation; Ischemia; Liver; Liver Abscess, Amebic; Macrophages; Necrosis; T-Lymphocytes | 1990 |