cyclosporine and Injuries, Spinal Cord

cyclosporine has been researched along with Injuries, Spinal Cord in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (12.12)18.2507
2000's18 (54.55)29.6817
2010's11 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Batty, NJ; Biernaskie, J; Fenrich, KK; Fouad, K; Führmann, T; Lucas-Osma, AM; May, Z; Raposo, P; Shoichet, M; Stykel, MG; Torres-Espín, A1
Hall, ED; Springer, JE; Sullivan, PG; Visavadiya, NP1
Chen, ZR; Guo, HH; Jin, QH; Lu, ZD; Ma, Y1
Antonios, JP; Ciacci, JD; Cleary, DR; Farah, GJ; Martin, JR; Pham, MH1
Jazayeri, SB; Rahimi-Movaghar, V1
Ban, DX; Chang, J; Cheng, SZ; Feng, SQ; Gao, SJ; Liu, Y; Ning, GZ; Wang, HJ; Wang, LL1
Franco-Bourland, RE; Grijalva, I; Guízar-Sahagún, G; Ibarra, A; Madrazo, I; Martínez-Cruz, A; Rodríguez-Balderas, CA1
Bravo, G; Hong, E; Ibarra, A; Rojas, G; Romero, SE1
Albermann, S; Barry, FP; Dockery, P; Garcia, Y; Hynes, J; McMahon, SS; Moran, C; O'Brien, T; Rooney, GE; Windebank, AJ1
Grotenhuis, A; Hurtado, A; Nandoe Tewarie, RD; Oudega, M; Rahiem, ST; Ritfeld, GJ; Roos, RA1
Boniface, G; Endres, R; Feifel, R; Gimenez y Ribotta, M; Lonjon, N; Perrin, FE; Privat, A1
Hu, JG; Lü, HZ; Wang, FC; Wang, YX; Zhou, JS1
Delaviz, H; Joghataie, MT; Mehdizadeh, M; Mirzaei, A; Roozbehi, A1
Hodgetts, SI; Plant, GW; Simmons, PJ1
Fairbanks, CA; Wilcox, GL; Yezierski, RP; Yu, CG1
Fischer, I; Murray, M; Shibata, M; Shumsky, JS; Tessler, A; Tobias, CA; Tuszynski, MH1
Diaz-Ruiz, A; Guizar-Sahagún, G; Ibarra, A; Perez-Severiano, F; Ríos, C; Segovia, J; Vergara, P2
Bunge, MB; Hill, CE; Moon, LD; Wood, PM1
Connors, T; Fischer, I; Hayashi, Y; Murray, M; Otsuka, T; Shumsky, JS; Tessler, A1
Cui, YJ; Fukuda, S; Matsumoto, M; Sakabe, T; Tsuruta, S; Wakamatsu, H; Yamashita, A1
Diaz-Ruiz, A; Ibarra, A1
Buenrostro, M; Correa, D; Flores, N; Garcia, E; Guizar-Sahagun, G; Hernández, E; Ibarra, A; Lomeli, J; Madrazo, I; Martiñón, S; Pineda, D1
McEwen, ML; Springer, JE; Sullivan, PG1
Choi, YK; Jeong, ES; Kim, HC; Lee, CH; Nam, KH; Park, HJ; Park, JI; Won, YS1
McEwen, ML; Ravikumar, R; Springer, JE1
Castañeda-Hernández, G; Correa, D; Espitia, AL; Flores-Murrieta, FJ; Franco-Bourland, R; Grijalva, I; Guízar-Sahagún, G; Ibarra, A; Kretschmer, R; López, RM; Madrazo, I; Odor, A; Salgado-Ceballos, H1
Castañeda-Hernández, G; Correa, D; Flores-Murrieta, FJ; Franco-Bourland, R; Grijalva, I; Guízar-Sahagún, G; Ibarra, A; Madrazo, I; Martínez, S; Reyes, J1
Chow, SY; Fischer, I; Himes, BT; Huang, W; Liu, Y; Moul, J; Tessler, A1
Correa, D; Diaz-Ruiz, A; Duarte, I; Grijalva, I; Guizar-Sahagun, G; Ibarra, A; Rios, C1
Correa, D; Diaz-Ruiz, A; Duarte, I; Grijalva, I; Guizar-Sahagun, G; Ibarra, A; Madrazo, I; Rios, C1
Gold, BG1
Fugaccia, I; Rabchevsky, AG; Scheff, SW; Sullivan, PG1

Reviews

3 review(s) available for cyclosporine and Injuries, Spinal Cord

ArticleYear
Immunosuppressive mechanisms for stem cell transplant survival in spinal cord injury.
    Neurosurgical focus, 2019, 03-01, Volume: 46, Issue:3

    Topics: Adjuvants, Immunologic; Allografts; Animals; Basiliximab; Cells, Cultured; Clinical Trials as Topic; Cyclosporine; Female; Graft Rejection; Graft Survival; Graft vs Host Disease; Human Embryonic Stem Cells; Humans; Immunosuppressive Agents; Induced Pluripotent Stem Cells; Male; Mice; Mycophenolic Acid; Oligodendrocyte Precursor Cells; Rats; Spinal Cord Injuries; Tacrolimus; Transplantation, Autologous

2019
Protective effect of cyclosporin-A in spinal cord injury: an overview.
    Current medicinal chemistry, 2006, Volume: 13, Issue:22

    Topics: Animals; Apoptosis; Calcineurin; Central Nervous System; Cyclosporine; Humans; Spinal Cord Injuries

2006
Neuroimmunophilin ligands: evaluation of their therapeutic potential for the treatment of neurological disorders.
    Expert opinion on investigational drugs, 2000, Volume: 9, Issue:10

    Topics: Animals; Brain Injuries; Carpal Tunnel Syndrome; Cyclosporine; Humans; Immunophilins; Immunosuppressive Agents; Ligands; Nerve Regeneration; Nervous System Diseases; Spinal Cord Injuries; Tacrolimus; Tacrolimus Binding Protein 1A

2000

Other Studies

30 other study(ies) available for cyclosporine and Injuries, Spinal Cord

ArticleYear
Cyclosporine-immunosuppression does not affect survival of transplanted skin-derived precursor Schwann cells in the injured rat spinal cord.
    Neuroscience letters, 2017, Sep-29, Volume: 658

    Topics: Animals; Cyclosporine; Disease Models, Animal; Female; Nerve Regeneration; Peripheral Nerves; Rats, Inbred F344; Recovery of Function; Schwann Cells; Spinal Cord; Spinal Cord Injuries

2017
Post-Injury Treatment with NIM811 Promotes Recovery of Function in Adult Female Rats after Spinal Cord Contusion: A Dose-Response Study.
    Journal of neurotrauma, 2018, 02-01, Volume: 35, Issue:3

    Topics: Animals; Cyclosporine; Dose-Response Relationship, Drug; Female; Neuroprotective Agents; Random Allocation; Rats; Rats, Long-Evans; Recovery of Function; Spinal Cord Injuries

2018
Therapeutic efficacy of cyclosporin A against spinal cord injury in rats with hyperglycemia.
    Molecular medicine reports, 2018, Volume: 17, Issue:3

    Topics: Animals; Apoptosis; Apoptosis Inducing Factor; Cyclophilins; Cyclosporine; Disease Models, Animal; Female; Gene Expression Regulation; Hyperglycemia; Interleukin-10; Motor Activity; Nerve Regeneration; Neuroglia; Neurons; Neuroprotective Agents; Peptidyl-Prolyl Isomerase F; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord; Spinal Cord Injuries; Streptozocin; Tumor Necrosis Factor-alpha

2018
When do we start Basso, Beattie, and Bresnahan assessment after experimental spinal cord injury?
    Acta medica Iranica, 2013, Sep-09, Volume: 51, Issue:8

    Topics: Animals; Axons; Cyclosporine; Female; Motor Neurons; Spinal Cord; Spinal Cord Injuries

2013
New approach to treating spinal cord injury using PEG-TAT-modified, cyclosporine-A-loaded PLGA/polymeric liposomes.
    Journal of drug targeting, 2017, Volume: 25, Issue:1

    Topics: Animals; Cyclosporine; Drug Carriers; Drug Liberation; Female; GAP-43 Protein; Gene Expression; Gene Products, tat; Lactic Acid; Liposomes; Nanoparticles; Nerve Regeneration; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Wistar; Spinal Cord; Spinal Cord Injuries

2017
Lack of neuroprotection with pharmacological pretreatment in a paradigm for anticipated spinal cord lesions.
    Spinal cord, 2009, Volume: 47, Issue:2

    Topics: Analysis of Variance; Animals; Cyclosporine; Disease Models, Animal; Erythropoietin; Female; Locomotion; Melatonin; Methylprednisolone; Neuroprotective Agents; Postoperative Complications; Rats; Rats, Long-Evans; Recombinant Proteins; Recovery of Function; Spinal Cord; Spinal Cord Injuries; Time Factors

2009
Acute, subacute and chronic effect of cyclosporin-A on mean arterial pressure of rats with severe spinal cord contusion.
    Neuroscience letters, 2008, Nov-07, Volume: 445, Issue:1

    Topics: Analysis of Variance; Animals; Blood Pressure; Cyclosporine; Disease Models, Animal; Female; Immunosuppressive Agents; Rats; Rats, Wistar; Spinal Cord Injuries; Time Factors

2008
Effect of cyclosporin A on functional recovery in the spinal cord following contusion injury.
    Journal of anatomy, 2009, Volume: 215, Issue:3

    Topics: Animals; Collagen; Cyclosporine; Drug Evaluation, Preclinical; Female; Hindlimb; Microscopy, Electron, Scanning; Nerve Regeneration; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord; Spinal Cord Injuries

2009
Reducing macrophages to improve bone marrow stromal cell survival in the contused spinal cord.
    Neuroreport, 2010, Feb-17, Volume: 21, Issue:3

    Topics: Animals; Bone Marrow Transplantation; Cyclosporine; Female; Graft Survival; Immunohistochemistry; Immunosuppressive Agents; Macrophages; Methylprednisolone; Minocycline; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Stromal Cells

2010
Potential adverse effects of cyclosporin A on kidneys after spinal cord injury.
    Spinal cord, 2011, Volume: 49, Issue:3

    Topics: Animals; Cell Transplantation; Cyclosporine; Disease Models, Animal; Drug Therapy, Combination; Graft Rejection; Immunosuppressive Agents; Kidney Diseases; Male; Rats; Rats, Wistar; Spinal Cord Injuries; Treatment Outcome

2011
Cyclosporin A increases recovery after spinal cord injury but does not improve myelination by oligodendrocyte progenitor cell transplantation.
    BMC neuroscience, 2010, Oct-12, Volume: 11

    Topics: Animals; Antimetabolites; Bromodeoxyuridine; Cell Differentiation; Cell Survival; Cells, Cultured; Cyclosporine; Female; Green Fluorescent Proteins; Immunohistochemistry; Immunosuppressive Agents; Locomotion; Motor Neurons; Myelin Sheath; Neural Stem Cells; Oligodendroglia; Rats; Rats, Sprague-Dawley; Receptor-CD3 Complex, Antigen, T-Cell; Recovery of Function; Spinal Cord; Spinal Cord Injuries; T-Lymphocytes

2010
The effects of cyclosporin-A on functional outcome and axonal regrowth following spinal cord injury in adult rats.
    Acta medica Iranica, 2012, Volume: 50, Issue:4

    Topics: Animals; Axons; Cyclosporine; Disease Models, Animal; Female; Hindlimb; Motor Activity; Motor Neurons; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord; Spinal Cord Injuries; Time Factors

2012
Human mesenchymal precursor cells (Stro-1⁺) from spinal cord injury patients improve functional recovery and tissue sparing in an acute spinal cord injury rat model.
    Cell transplantation, 2013, Volume: 22, Issue:3

    Topics: Animals; Bone Marrow Cells; Cyclosporine; Disease Models, Animal; Female; Graft Rejection; Humans; Immunohistochemistry; Immunosuppressive Agents; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Rats; Rats, Nude; Recovery of Function; Sensory Receptor Cells; Serotonergic Neurons; Spinal Cord Injuries

2013
Effects of agmatine, interleukin-10, and cyclosporin on spontaneous pain behavior after excitotoxic spinal cord injury in rats.
    The journal of pain, 2003, Volume: 4, Issue:3

    Topics: Agmatine; Animals; Cyclosporine; Disease Models, Animal; Excitatory Amino Acid Agonists; Grooming; Immunosuppressive Agents; Interleukin-10; Male; Pain; Quisqualic Acid; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Time Factors

2003
Delayed grafting of BDNF and NT-3 producing fibroblasts into the injured spinal cord stimulates sprouting, partially rescues axotomized red nucleus neurons from loss and atrophy, and provides limited regeneration.
    Experimental neurology, 2003, Volume: 184, Issue:1

    Topics: Animals; Atrophy; Axotomy; Biotin; Brain-Derived Neurotrophic Factor; Cell Count; Cell Size; Cell Survival; Cyclosporine; Dextrans; Female; Fibroblasts; GAP-43 Protein; Green Fluorescent Proteins; Immunohistochemistry; Immunosuppressive Agents; Luminescent Proteins; Nerve Regeneration; Neurons; Neurotrophin 3; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Red Nucleus; Spinal Cord Injuries

2003
Cyclosporin-A inhibits inducible nitric oxide synthase activity and expression after spinal cord injury in rats.
    Neuroscience letters, 2004, Feb-26, Volume: 357, Issue:1

    Topics: Animals; Cyclosporine; Disease Models, Animal; Female; I-kappa B Proteins; Immunosuppressive Agents; Nerve Degeneration; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Spinal Cord Injuries; Transcription, Genetic

2004
Cyclosporin-A inhibits constitutive nitric oxide synthase activity and neuronal and endothelial nitric oxide synthase expressions after spinal cord injury in rats.
    Neurochemical research, 2005, Volume: 30, Issue:2

    Topics: Actins; Animals; Blotting, Western; Calcineurin Inhibitors; Cyclosporine; Enzyme Inhibitors; Female; Immunosuppressive Agents; Nerve Tissue Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Phosphorylation; Rats; Rats, Wistar; Spinal Cord Injuries

2005
Labeled Schwann cell transplantation: cell loss, host Schwann cell replacement, and strategies to enhance survival.
    Glia, 2006, Volume: 53, Issue:3

    Topics: Alkaline Phosphatase; Animals; Apoptosis; Cell Survival; Cyclosporine; Female; Humans; Immunosuppressive Agents; Necrosis; Nitroblue Tetrazolium; Placenta; Rats; Rats, Inbred F344; Receptor, Nerve Growth Factor; Schwann Cells; Spinal Cord Injuries

2006
Immunosuppression with either cyclosporine a or FK506 supports survival of transplanted fibroblasts and promotes growth of host axons into the transplant after spinal cord injury.
    Journal of neurotrauma, 2005, Volume: 22, Issue:11

    Topics: Animals; Animals, Genetically Modified; Axons; Combined Modality Therapy; Cyclosporine; Female; Fibroblasts; Graft Survival; Immunosuppressive Agents; Nerve Regeneration; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Spinal Cord Injuries; Tacrolimus

2005
The effects of cyclosporin A and insulin on ischemic spinal cord injury in rabbits.
    Anesthesia and analgesia, 2006, Volume: 102, Issue:6

    Topics: Animals; Blood Glucose; Brain; Capillary Permeability; Cyclosporine; Hindlimb; Insulin; Lumbar Vertebrae; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Movement; Neurons; Neuroprotective Agents; Paraplegia; Rabbits; Spinal Cord; Spinal Cord Injuries; Spinal Cord Ischemia

2006
Cyclosporin-A enhances non-functional axonal growing after complete spinal cord transection.
    Brain research, 2007, May-29, Volume: 1149

    Topics: Animals; Axons; Blotting, Western; Cyclosporine; Electrophysiology; Female; GAP-43 Protein; Immunohistochemistry; Nerve Regeneration; Neuroprotective Agents; Pyramidal Tracts; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord Injuries

2007
Pretreatment with the cyclosporin derivative, NIM811, improves the function of synaptic mitochondria following spinal cord contusion in rats.
    Journal of neurotrauma, 2007, Volume: 24, Issue:4

    Topics: Animals; Biomechanical Phenomena; Chromatography, High Pressure Liquid; Contusions; Cyclosporine; Female; Mass Spectrometry; Mitochondria; Oxygen Consumption; Rats; Rats, Long-Evans; Reactive Oxygen Species; Spinal Cord Injuries; Synapses

2007
Upregulation of galectin-3 by Corynebacterium kutscheri infection in the rat lung.
    Experimental animals, 2007, Volume: 56, Issue:2

    Topics: Animals; Corynebacterium; Corynebacterium Infections; Cyclosporine; Disease Models, Animal; Galectin 3; Gene Expression Regulation, Bacterial; Immunocompromised Host; Immunosuppressive Agents; Lung; Macrophages, Alveolar; Male; Necrosis; Pneumonia, Pneumococcal; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; RNA, Bacterial; Specific Pathogen-Free Organisms; Spinal Cord Injuries; Staphylococcus aureus

2007
Post-treatment with the cyclosporin derivative, NIM811, reduced indices of cell death and increased the volume of spared tissue in the acute period following spinal cord contusion.
    Journal of neurotrauma, 2007, Volume: 24, Issue:10

    Topics: Animals; Apoptosis; Cyclosporine; Cytochromes c; Cytosol; DNA Fragmentation; Enzyme-Linked Immunosorbent Assay; Female; Image Processing, Computer-Assisted; Neuroprotective Agents; Rats; Rats, Long-Evans; Spinal Cord Injuries; Time

2007
Alteration of cyclosporin-A pharmacokinetics after experimental spinal cord injury.
    Journal of neurotrauma, 1996, Volume: 13, Issue:5

    Topics: Administration, Oral; Animals; Area Under Curve; Biological Availability; Cyclosporine; Female; Half-Life; Immunosuppressive Agents; Injections, Intraperitoneal; Rats; Spinal Cord Injuries

1996
Use of cyclosporin-A in experimental spinal cord injury: design of a dosing strategy to maintain therapeutic levels.
    Journal of neurotrauma, 1996, Volume: 13, Issue:10

    Topics: Animals; Cyclosporine; Female; Immunosuppressive Agents; Injections, Intraperitoneal; Rats; Spinal Cord; Spinal Cord Injuries

1996
Application of recombinant adenovirus for in vivo gene delivery to spinal cord.
    Brain research, 1997, Sep-12, Volume: 768, Issue:1-2

    Topics: Adenoviridae; Animals; Antibody Formation; beta-Galactosidase; Cyclosporine; Female; Gene Transfer Techniques; Genes, Reporter; Immunosuppressive Agents; Injections, Spinal; Rats; Rats, Sprague-Dawley; Recombination, Genetic; Spinal Cord Injuries; Transgenes

1997
Cyclosporin-A inhibits lipid peroxidation after spinal cord injury in rats.
    Neuroscience letters, 1999, Apr-30, Volume: 266, Issue:1

    Topics: Animals; Cyclosporine; Depression, Chemical; Female; Immunosuppressive Agents; Lipid Peroxidation; Rats; Rats, Wistar; Spinal Cord; Spinal Cord Injuries

1999
Lipid peroxidation inhibition in spinal cord injury: cyclosporin-A vs methylprednisolone.
    Neuroreport, 2000, Jun-05, Volume: 11, Issue:8

    Topics: Animals; Cyclosporine; Drug Combinations; Female; Lipid Peroxides; Methylprednisolone; Neuroprotective Agents; Rats; Rats, Wistar; Spinal Cord Injuries; Survival Analysis

2000
Cyclosporin A treatment following spinal cord injury to the rat: behavioral effects and stereological assessment of tissue sparing.
    Journal of neurotrauma, 2001, Volume: 18, Issue:5

    Topics: Animals; Cyclosporine; Female; Immunosuppressive Agents; Male; Motor Activity; Paralysis; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries; Stereotaxic Techniques; Thoracic Vertebrae

2001