cyclosporine and Huntington Disease

cyclosporine has been researched along with Huntington Disease in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's8 (88.89)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gellerich, FN; Gizatullina, Z; Landwehrmeyer, B; Nguyen, HP; Riess, O; Seppet, E; Striggow, F; Trumbeckaite, S; Vielhaber, S; von Hörsten, S; Zierz, S1
Choo, YS; Detloff, PJ; Johnson, GV; Lesort, M; MacDonald, M1
Greenamyre, JT; Lund, S; Panov, AV1
Cattaneo, E; Goffredo, D; Rigamonti, D; Tartari, M; Valenza, M; Zuccato, C1
Hernández-Espinosa, D; Morton, AJ1
Baimbridge, KG; Church, J; Fernandes, HB; Hayden, MR; Raymond, LA1
Barker, RA; Brooks, DJ; Chaudhuri, KR; Clough, C; Mason, S; Pavese, N; Piccini, P; Polkey, CE; Reuter, I; Tai, YF1
Kondoh, T; Low, WC; Pundt, LL1
Bachoud-Lévi, A; Barba, GD; Bartolomeo, P; Boissé, MF; Bourdet, C; Brugières, P; Cesaro, P; Defer, GL; Degos, JD; Ergis, AM; Grandmougin, T; Haddad, B; Hantraye, P; Jény, R; Lefaucheur, JP; Lisovoski, F; Nguyen, JP; Pailhous, E; Palfi, S; Peschanski, M; Rémy, P1

Trials

2 trial(s) available for cyclosporine and Huntington Disease

ArticleYear
Long-term clinical and positron emission tomography outcome of fetal striatal transplantation in Huntington's disease.
    Journal of neurology, neurosurgery, and psychiatry, 2008, Volume: 79, Issue:8

    Topics: Adrenergic Uptake Inhibitors; Adult; Brain Edema; Brain Tissue Transplantation; Carbon Radioisotopes; Case-Control Studies; Caudate Nucleus; Combined Modality Therapy; Corpus Striatum; Cyclosporine; Dopamine Antagonists; Female; Fetal Tissue Transplantation; Follow-Up Studies; Humans; Huntington Disease; Immunosuppressive Agents; Lymphocytosis; Male; Middle Aged; Morpholines; Neurologic Examination; Neuropsychological Tests; Positron-Emission Tomography; Postoperative Complications; Putamen; Raclopride; Reboxetine; Stereotaxic Techniques; Tissue Survival

2008
Safety and tolerability assessment of intrastriatal neural allografts in five patients with Huntington's disease.
    Experimental neurology, 2000, Volume: 161, Issue:1

    Topics: Adult; Brain Tissue Transplantation; Cognition; Corpus Striatum; Cyclosporine; Family; Female; Fetal Tissue Transplantation; Follow-Up Studies; Humans; Huntington Disease; Immunosuppressive Agents; Magnetic Resonance Imaging; Male; Middle Aged; Patient Satisfaction; Postoperative Care; Preoperative Care; Safety; Treatment Outcome

2000

Other Studies

7 other study(ies) available for cyclosporine and Huntington Disease

ArticleYear
Impaired regulation of brain mitochondria by extramitochondrial Ca2+ in transgenic Huntington disease rats.
    The Journal of biological chemistry, 2008, Nov-07, Volume: 283, Issue:45

    Topics: Animals; Brain; Calcium; Cell Death; Coloring Agents; Cyclosporine; Energy Metabolism; Enzyme Inhibitors; Humans; Huntingtin Protein; Huntington Disease; Membrane Potential, Mitochondrial; Mitochondria; Nerve Tissue Proteins; Nuclear Proteins; Oxygen Consumption; Rats; Rats, Transgenic; Ruthenium Red

2008
Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release.
    Human molecular genetics, 2004, Jul-15, Volume: 13, Issue:14

    Topics: Adenosine Triphosphate; Animals; Calcium; Cell Line; Cyclosporine; Cytochromes c; Humans; Huntingtin Protein; Huntington Disease; Intracellular Membranes; Ion Channels; Mice; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mutation; Nerve Tissue Proteins; Nuclear Proteins; Recombinant Proteins; Serotonin Plasma Membrane Transport Proteins

2004
Ca2+-induced permeability transition in human lymphoblastoid cell mitochondria from normal and Huntington's disease individuals.
    Molecular and cellular biochemistry, 2005, Volume: 269, Issue:1-2

    Topics: Adenosine Diphosphate; Adolescent; Animals; Calcium; Cations, Divalent; Cyclosporine; Enzyme Inhibitors; Humans; Huntingtin Protein; Huntington Disease; Leukocytes; Mitochondria; Mitochondrial Swelling; Nerve Tissue Proteins; Nuclear Proteins; Oligomycins; Permeability; Rats

2005
Prevention of cytosolic IAPs degradation: a potential pharmacological target in Huntington's Disease.
    Pharmacological research, 2005, Volume: 52, Issue:2

    Topics: Animals; Apoptosis Regulatory Proteins; Brain; Carrier Proteins; Cell Line; Cell Survival; Cyclosporine; Cytosol; High-Temperature Requirement A Serine Peptidase 2; Humans; Huntingtin Protein; Huntington Disease; Inhibitor of Apoptosis Proteins; Intracellular Signaling Peptides and Proteins; Mice; Mitochondria; Mitochondrial Proteins; Mutation; Nerve Tissue Proteins; Nuclear Proteins; Proteins; Pyrimidinones; Serine Endopeptidases; Thiones; Ubiquitin-Protein Ligases; X-Linked Inhibitor of Apoptosis Protein

2005
Calcineurin inhibitors cause an acceleration of the neurological phenotype in a mouse transgenic for the human Huntington's disease mutation.
    Brain research bulletin, 2006, May-31, Volume: 69, Issue:6

    Topics: Analysis of Variance; Animals; Blood Glucose; Calcineurin; Calcineurin Inhibitors; Cyclosporine; Disease Models, Animal; Glycosuria; Humans; Huntington Disease; Immunohistochemistry; Immunosuppressive Agents; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Mutation; Psychomotor Performance; Tacrolimus; Time Factors; Trinucleotide Repeat Expansion

2006
Mitochondrial sensitivity and altered calcium handling underlie enhanced NMDA-induced apoptosis in YAC128 model of Huntington's disease.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Dec-12, Volume: 27, Issue:50

    Topics: Animals; Apoptosis; Bongkrekic Acid; Calcium; Calcium Signaling; Cells, Cultured; Cyclosporine; Disease Models, Animal; Excitatory Amino Acid Agonists; Fluorescent Dyes; Huntington Disease; Ionophores; Mice; Mice, Neurologic Mutants; Mitochondria; N-Methylaspartate; Neurotoxins; Patch-Clamp Techniques; Receptors, N-Methyl-D-Aspartate; Trinucleotide Repeat Expansion

2007
NADPH-diaphorase histochemistry and functional analysis of human fetal striatal brain tissue transplanted into a rodent model of Huntington's disease.
    Transplantation proceedings, 1994, Volume: 26, Issue:6

    Topics: Animals; Biomarkers; Brain Tissue Transplantation; Cyclosporine; Disease Models, Animal; Fetal Tissue Transplantation; Histocytochemistry; Humans; Huntington Disease; Motor Activity; NADPH Dehydrogenase; Neuropeptide Y; Rats; Rats, Sprague-Dawley; Rotation; Somatostatin

1994