cyclosporine and Glioma

cyclosporine has been researched along with Glioma in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (16.67)18.2507
2000's14 (58.33)29.6817
2010's6 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baksh, S; Brun, M; Glubrecht, DD; Godbout, R1
Simpkins, JW; Yi, KD1
Choi, HJ; Ha, EY; Han, SY; Jin, KB; Kim, HC; Kim, YH; Lee, KT; Mun, KC; Park, SB1
Anderson, RA; Panickar, KS; Polansky, MM1
Amoroso, R; Bartoli, B; Benvenuti, L; Gagliardi, R; Gremigni, V; Lena, A; Rechichi, M; Rossi, L; Salvetti, A; Scarcelli, V; Vecchio, D1
Juhnn, YS; Kim, SY; Kim, Y; Kim, YS; Lee, JE; Lee, YI; Seo, M; Youn, HD1
Choi, TG; Choi, WJ; Ding, Y; Ha, J; Han, X; Huh, YB; Kim, SS; Kim, YH; Kim, YJ; Yoon, SH1
Ha, EY; Mun, KH1
Chen, CH; Lin, ML; Ong, PL; Yang, JT1
Ciechomska, IA; Gabrusiewicz, K; Kaminska, B; Szczepankiewicz, AA1
Ciechomska, IA; Kaminska, B1
Ciechomska, I; Kaminska, B; Kazmierczak, P; Pyrzynska, B1
Agafonov, A; Belosludtsev, K; Dubois, M; Gateau-Roesch, O; Gritsenko, E; Levrat, C; Mironova, GD; Muntean, D; Ovize, M; Prigent, AF1
Gu, SH; Hui, GZ; Li, Y; Qi, ZY; Xie, Y; Ying, K; Zhou, ZX1
Dziembowska, M; Ellert-Miklaszewska, A; Gaweda-Walerych, K; Kaminska, B; Zupanska, A1
Ali, S; Candolfi, M; Castro, MG; Cheng, Q; Curtin, JF; King, GD; Kupiec-Weglinski, J; Lassmann, H; Liu, C; Lowenstein, PR; Prieto, J; Puntel, M; Ribas, A; van Rooijen, N; Xiong, W1
Bernstein, M; Blaney, S; Chen, Z; Fisher, PG; Freeman, C; Friedman, H; Greenberg, ML; Hershon, L; Korones, DN; Kretschmar, C; Zhou, T1
Figiel, I; Kaminska, B; Mosieniak, G1
Boval, B; Chappey, O; Debray, M; El Hafny, B; Piciotti, M; Roux, F1
Kaminska, B; Mosieniak, G; Pyrzynska, B2
Badovinac, V; Janković, V; Mostarica Stojković, M; Trajković, V1
Dohgu, S; Ikesue, H; Kataoka, Y; Kawachi, R; Oishi, R; Shuto, H1
Kaminska, B; Martínez-A, C; Pyrzynska, B; Serrano, M1

Trials

1 trial(s) available for cyclosporine and Glioma

ArticleYear
Etoposide, vincristine, and cyclosporin A with standard-dose radiation therapy in newly diagnosed diffuse intrinsic brainstem gliomas: a pediatric oncology group phase I study.
    Pediatric blood & cancer, 2005, Oct-15, Volume: 45, Issue:5

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brain Stem Neoplasms; Child; Child, Preschool; Combined Modality Therapy; Cyclosporine; Disease Progression; Dose Fractionation, Radiation; Etoposide; Glioma; Humans; Radiotherapy Dosage; Vincristine

2005

Other Studies

23 other study(ies) available for cyclosporine and Glioma

ArticleYear
Calcineurin regulates nuclear factor I dephosphorylation and activity in malignant glioma cell lines.
    The Journal of biological chemistry, 2013, Aug-16, Volume: 288, Issue:33

    Topics: Adult; Astrocytoma; Calcineurin; Calcium-Binding Proteins; Cell Line, Tumor; Chromatin Immunoprecipitation; Cyclosporine; Glioma; Humans; Immunohistochemistry; Immunoprecipitation; Ionomycin; NFI Transcription Factors; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Protein Transport

2013
Protein phosphatase 1, protein phosphatase 2A, and calcineurin play a role in estrogen-mediated neuroprotection.
    Endocrinology, 2008, Volume: 149, Issue:10

    Topics: Animals; Brain Neoplasms; Calcineurin; Calcineurin Inhibitors; Cell Line, Tumor; Cell Survival; Cyclosporine; Dicarboxylic Acids; Drug Interactions; Enzyme Inhibitors; Estrogens; Glioma; Glutamic Acid; Mice; Neurons; Neuroprotective Agents; Neurotoxins; Okadaic Acid; Oxidative Stress; Protein Phosphatase 1; Protein Phosphatase 2; Rats; Stroke

2008
Effects of cyclosporine on the production of the reactive oxygen species in the glial cells.
    Transplantation proceedings, 2008, Volume: 40, Issue:8

    Topics: Animals; Cyclosporine; Free Radicals; Glioma; Kinetics; Rats; Reactive Oxygen Species

2008
Cinnamon polyphenols attenuate cell swelling and mitochondrial dysfunction following oxygen-glucose deprivation in glial cells.
    Experimental neurology, 2009, Volume: 216, Issue:2

    Topics: Animals; Cell Line, Tumor; Cell Size; Cinnamomum zeylanicum; Cyclosporine; Dose-Response Relationship, Drug; Flavonoids; Gene Expression Regulation; Glioma; Glucose; Hypoxia; Immunosuppressive Agents; Insulin; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Nitric Oxide; Phenols; Plant Extracts; Polyphenols; Rats; Time Factors

2009
Drugs targeting the mitochondrial pore act as cytotoxic and cytostatic agents in temozolomide-resistant glioma cells.
    Journal of translational medicine, 2009, Feb-05, Volume: 7

    Topics: Acridine Orange; Betulinic Acid; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Death; Cell Line, Tumor; Cell Survival; Cyclosporine; Cytostatic Agents; Dacarbazine; Drug Resistance, Neoplasm; ErbB Receptors; Glioma; Humans; Indazoles; Membrane Potential, Mitochondrial; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Pentacyclic Triterpenes; Polymerase Chain Reaction; Retinoids; Temozolomide; Triterpenes

2009
Calcineurin dephosphorylates glycogen synthase kinase-3 beta at serine-9 in neuroblast-derived cells.
    Journal of neurochemistry, 2009, Volume: 111, Issue:2

    Topics: Animals; Calcineurin; Calcineurin Inhibitors; Cell Line, Tumor; Cyclosporine; Enzyme Activation; Enzyme Inhibitors; Glioma; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Male; Mice; Mutation; Neuroblastoma; Neurons; Phosphorylation; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Serine; Tacrolimus; Transfection

2009
Cyclosporin A and sanglifehrin A enhance chemotherapeutic effect of cisplatin in C6 glioma cells.
    Oncology reports, 2010, Volume: 23, Issue:4

    Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cisplatin; Cyclophilin A; Cyclosporine; Drug Synergism; Glioma; Humans; Immunohistochemistry; Lactones; Rats; Reactive Oxygen Species; RNA, Small Interfering; Spiro Compounds

2010
Effects of cyclosporine on the antioxidant status and oxidative stress in the glioma cells.
    Transplantation proceedings, 2010, Volume: 42, Issue:3

    Topics: Animals; Antioxidants; Cyclosporine; Glioma; Hydrogen Peroxide; Malondialdehyde; Oxidative Stress; Rats

2010
Novel multiple apoptotic mechanism of shikonin in human glioma cells.
    Annals of surgical oncology, 2012, Volume: 19, Issue:9

    Topics: Acetylcysteine; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; bcl-2-Associated X Protein; Benzothiazoles; Catalase; Cell Line, Tumor; Cyclosporine; G1 Phase Cell Cycle Checkpoints; Glioma; Glutathione; Humans; Membrane Potential, Mitochondrial; Mitochondria; Naphthoquinones; Oxidative Stress; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Superoxide Dismutase; Superoxide Dismutase-1; Toluene; Tumor Suppressor Protein p53

2012
Endoplasmic reticulum stress triggers autophagy in malignant glioma cells undergoing cyclosporine a-induced cell death.
    Oncogene, 2013, Mar-21, Volume: 32, Issue:12

    Topics: Animals; Apoptosis; Autophagy; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Cyclosporine; eIF-2 Kinase; Endoplasmic Reticulum Stress; Glioma; Humans; Rats; TOR Serine-Threonine Kinases

2013
ER stress and autophagy contribute to CsA-induced death of malignant glioma cells.
    Autophagy, 2012, Volume: 8, Issue:10

    Topics: Animals; Autophagy; Cell Line, Tumor; Cyclosporine; Drug Resistance, Neoplasm; Endoplasmic Reticulum Stress; Glioma; Humans; Models, Biological; Rats

2012
Inhibition of Akt kinase signalling and activation of Forkhead are indispensable for upregulation of FasL expression in apoptosis of glioma cells.
    Oncogene, 2003, Oct-23, Volume: 22, Issue:48

    Topics: Animals; Apoptosis; Cell Line, Tumor; Cyclosporine; Fas Ligand Protein; Forkhead Transcription Factors; Glioma; Membrane Glycoproteins; Nuclear Proteins; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; RNA, Messenger; Signal Transduction; Transcription Factors; Transcription, Genetic; Up-Regulation

2003
Formation of palmitic acid/Ca2+ complexes in the mitochondrial membrane: a possible role in the cyclosporin-insensitive permeability transition.
    Journal of bioenergetics and biomembranes, 2004, Volume: 36, Issue:2

    Topics: Animals; Calcium; Cell Line, Tumor; Cell Membrane Permeability; Cells, Cultured; Cyclosporine; Fibrosarcoma; Glioma; Intracellular Membranes; Liposomes; Membranes, Artificial; Mice; Mitochondria, Liver; Osmotic Pressure; Palmitic Acid; Rats; Water-Electrolyte Balance

2004
cDNA microarray in isolation of novel differentially expressed genes related to human glioma and clone of a novel full-length gene.
    Chinese medical journal, 2005, May-20, Volume: 118, Issue:10

    Topics: Amino Acid Sequence; Base Sequence; Blotting, Northern; Cyclophilins; Cyclosporine; Glioma; Humans; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; RNA, Messenger

2005
Cyclosporine a induces growth arrest or programmed cell death of human glioma cells.
    Neurochemistry international, 2005, Volume: 47, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Caspases; Cell Line, Tumor; Cell Proliferation; Cell Shape; Cellular Senescence; Chromatin; Collagen Type XI; Cyclosporine; Enzyme Activation; Glioma; Growth Inhibitors; Humans; Immunosuppressive Agents; Protein Synthesis Inhibitors; Tumor Suppressor Protein p53; Vacuoles

2005
Combined immunostimulation and conditional cytotoxic gene therapy provide long-term survival in a large glioma model.
    Cancer research, 2005, Aug-15, Volume: 65, Issue:16

    Topics: Adenoviruses, Human; Adjuvants, Immunologic; Amino Acid Sequence; Animals; Autoimmunity; Brain; Brain Neoplasms; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Combined Modality Therapy; Cyclosporine; Genetic Therapy; Genetic Vectors; Glioma; Herpesvirus 1, Human; Humans; Killer Cells, Natural; Macrophages; Male; Membrane Proteins; Molecular Sequence Data; Rats; Rats, Inbred Lew; Spinal Cord; Thymidine Kinase

2005
Cyclosporin A, an immunosuppressive drug, induces programmed cell death in rat C6 glioma cells by a mechanism that involves the AP-1 transcription factor.
    Journal of neurochemistry, 1997, Volume: 68, Issue:3

    Topics: Animals; Apoptosis; Cyclosporine; DNA; Glioma; Immunosuppressive Agents; Rats; Transcription Factor AP-1; Tumor Cells, Cultured

1997
Modulation of P-glycoprotein activity by glial factors and retinoic acid in an immortalized rat brain microvessel endothelial cell line.
    Neuroscience letters, 1997, Oct-31, Volume: 236, Issue:2

    Topics: Animals; Astrocytes; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Cell Line; Colchicine; Culture Media, Conditioned; Cyclosporine; Dose-Response Relationship, Drug; Endothelium, Vascular; Glioma; Microcirculation; Rats; Tretinoin; Tumor Cells, Cultured; Vinblastine

1997
Nuclear factor of activated T cells (NFAT) as a new component of the signal transduction pathway in glioma cells.
    Journal of neurochemistry, 1998, Volume: 71, Issue:1

    Topics: Animals; Apoptosis; Carcinogens; Cyclic AMP Response Element-Binding Protein; Cyclosporine; Cytoplasm; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Glioma; Interleukin-2; NFATC Transcription Factors; Nuclear Proteins; Phosphorylation; Promoter Regions, Genetic; Rats; Signal Transduction; T-Lymphocytes; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured

1998
Cyclosporin A inhibits activation of inducible nitric oxide synthase in C6 glioma cell line.
    Brain research, 1999, Jan-16, Volume: 816, Issue:1

    Topics: Animals; Calcineurin Inhibitors; Cyclosporine; DNA-Binding Proteins; Enzyme Activation; Glioma; Interferon Regulatory Factor-1; Interferon-gamma; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phosphoproteins; Rats; RNA, Messenger; Tacrolimus; Tumor Cells, Cultured

1999
Changes of the trans-activating potential of AP-1 transcription factor during cyclosporin A-induced apoptosis of glioma cells are mediated by phosphorylation and alterations of AP-1 composition.
    Journal of neurochemistry, 2000, Volume: 74, Issue:1

    Topics: Animals; Apoptosis; Cell Division; Cyclosporine; Glioma; Humans; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Promoter Regions, Genetic; Rats; Transcription Factor AP-1; Transcriptional Activation; Tumor Cells, Cultured

2000
Cyclosporine enhances alpha1-adrenoceptor-mediated nitric oxide production in C6 glioma cells.
    European journal of pharmacology, 2000, Nov-03, Volume: 407, Issue:3

    Topics: Adrenergic alpha-Agonists; Cyclosporine; Enzyme Inhibitors; Glioma; Humans; Immunosuppressive Agents; Nitric Oxide; omega-N-Methylarginine; Phenylephrine; Receptors, Adrenergic, alpha-1; Tumor Cells, Cultured

2000
Tumor suppressor p53 mediates apoptotic cell death triggered by cyclosporin A.
    The Journal of biological chemistry, 2002, Apr-19, Volume: 277, Issue:16

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Northern; Blotting, Western; Cell Division; Cell Line; Cell Nucleus; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cyclosporine; Fibroblasts; Genes, Dominant; Glioma; Immunoblotting; Kinetics; Mice; Mice, Knockout; Microscopy, Fluorescence; Mitochondria; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Plasmids; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; RNA; Time Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Up-Regulation

2002