Compounds > cyclosporine

cyclosporine and Genetic Predisposition

cyclosporine has been researched along with Genetic Predisposition in 46 studies

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (8.70)18.2507
2000's16 (34.78)29.6817
2010's23 (50.00)24.3611
2020's3 (6.52)2.80

Authors

AuthorsStudies
Basu, RC; Gan, SH; Guad, RM; Liew, CSL; Taylor-Robinson, AW; Wan Md Adnan, WAH; Wu, YS; Zaharan, NL1
Babushok, D; Bagg, A; Hurwitz, SN; Juusola, J; Sklarz, T; Stanley, NL1
Andreani, M; Artesani, MC; Buzzonetti, L; Esposito, M; Fiocchi, A; Locatelli, F; Mennini, M1
Cao, Q; Deng, J; Kijlstra, A; Qiu, Y; Su, W; Yang, P; Ye, Z; Yu, H; Yuan, G; Zhu, Y1
Chatzopoulos, GS; Koidou, VP; Wolff, LF1
Jiao, Z; Qiu, XY; Xu, QX; Zhang, M; Zhong, MK1
De' Angelis, GL; Di Mario, F; Fusco, C; Gaiani, F; Leandro, G; Pisani, F; Spagnoli, C1
Cairo, M; Camitta, BM; Carpenter, PA; Chan, KW; Diaz Perez, MA; Doyle, J; Eapen, M; Fraser, C; Gross, TG; He, W; Hitzler, JK; Horan, JT; Kennedy-Nasser, AA; Kitko, C; Kurtzberg, J; Lehmann, L; O'Brien, T; Pulsipher, MA; Smith, FO; Zhang, MJ1
Davis, RM; Grubbs, J; Huynh, K; Liu, KC1
Huang, H; Li, YQ; Liu, HM; Wu, XC; Xin, HW; Yu, AR; Zhang, L1
Abraham, G; Ali, AA; Mathew, M; Mehra, N; Nagarajan, P; Ramachandran, A; Reddy, PP; Reddy, YN; Sundaram, V1
Baig, S; Bamborschke, D; Beck, BB; Büscher, AK; Hoefele, J; Hoyer, PF; Jungraithmayr, T; Kemper, MJ; Konrad, M; Kranz, B; Lange-Sperandio, B; Melk, A; Tönshoff, B; Weber, LT; Weber, S1
Berbée, JF; Deswaerte, V; Glaros, E; Jessup, W; Kockx, M; Kritharides, L; Leung, B; Meikle, PJ; Nawara, D; Ng, TW; Quinn, C; Rensen, PC; Rye, KA1
Cho, KJ; Choi, C; Choi, JH; Choi, YJ; Gee, HY; Kim, SW; Kim, TH; Kwon, EY; Noh, SH; Park, HJ1
Andress, EJ; Linton, KJ; McGeoghan, F; Nicolaou, M1
Li, KX; Shao, H; Shi, LW; Sun, CH; Yang, LP; Zhang, YT1
Blough, DK; Davis, CL; Farin, FM; Hebert, MF; Jones, JP; Kalhorn, TF; Perkins, JD; Smith, HE; Stapleton, PL; Thummel, KE; Totah, RA1
Arizon, J; Aumente, MD; Isla-Tejera, B; Lorite, P; Luque, J; Palomeque, T; Peña, J; Torres, MI1
Broadfoot, AJ; Fernando, SL1
Ansari, IU; Fernandes, F; Striker, R1
Brown, DC; Casal, ML; Mauldin, EA; Morris, DO1
Büscher, AK; Büscher, R; Dworniczak, B; Hildebrandt, F; Hoyer, PF; John, U; Kemper, M; Konrad, M; Kranz, B; Kuwertz-Bröking, E; Monnens, L; Pennekamp, P; Weber, S; Wingen, AM1
Bae, JY; Han, KS; Hong, YC; Kim, BK; Kim, HK; Kim, I; Kim, JH; Kwon, JH; Lee, DS; Lee, JE; Lee, YG; Park, MH; Park, S; Park, SS; Shin, DY; Song, EY; Yoon, SS1
O'Rielly, DD; Rahman, P1
Krilis, M; Miyakis, S1
Guan, W; Israni, A; Jacobson, PA; Lamba, V; Leduc, R; Lin, YC; Matas, AJ; Oetting, WS; Schladt, D1
Paolella, G; Vajro, P1
Cohen, SA; Ferry, GD; Gold, BD; Gupta, N; Heyman, MB; Jen, HC; Kelley-Quon, LI; Kirschner, BS; Shew, SB; Winter, HS; Ziring, DA1
Benítez, J; Caravaca, F; Cubero, JJ; García, M; Gervasini, G; Macías, RM1
Cheung, YB; Chowbay, B; Cumaraswamy, S; Lee, EJ; Zhou, Q1
Bednarczuk, T; Makowska, U; Nauman, J1
Bonanini, M; Manfredi, M; Meleti, M; Vescovi, P1
Cullen, BR1
Bardy, P; Doherty, K; Grigg, A; Heatley, S; Hughes, T; Mullighan, C; Schwarer, A; Szabo, F; Szer, J; Tait, B; To, B1
Bartoli, F; Castronovo, G; Stabile, A1
Ackermann, H; Eichelbaum, M; Gauer, S; Geiger, H; Gossmann, J; Hauser, IA; Hocher, B; Schaeffeler, E; Scheuermann, EH; Schwab, M; Seidl, C; Wegner, B; Zanger, UM1
Breschi, L; Cadenaro, M; Cocco, L; Matteucci, A; Montebugnoli, L; Ruggeri, A; Servidio, D; Solimando, L; Suppa, P; Zini, N1
Beck, Y; Kamatani, N; Mushiroda, T; Nakamura, Y; Ohnishi, Y; Saito, S; Tahara, H; Takasaki, J; Tanaka, Y1
Atilla, G; Bostanci, N; Clarke, FM; Hughes, FJ; Ilgenli, T; Marcenes, W; McKay, IJ; Pirhan, DC1
Murray, KF1
Chuhjo, T; Kaneshige, T; Matsuda, T; Mizoguchi, H; Nakao, S; Shiobara, S; Takamatsu, H; Ueda, M1
Burgers, SA; van Vloten, WA1
Asai, A; Chi, S; Hamada, H; Kirino, T; Kuchino, Y; Narita, Y; Qiu, Jh; Saito, N; Shinoura, N1
Amenábar, JJ; Gaínza, FJ; Gómez-Ullate, P; Lampreabe, I; Urbizu, JM; Zárraga, S1
Aguilar-Salinas, CA; Alberú, J; Arellano, A; Correa-Rotter, R; Díaz-Polanco, A; Gómez Pérez, FJ; Macias, N; Ordóñez, ML; Quintana, E; Ramírez, E; Velásquez-Alva, C1
Remuzzi, G; Ruggenenti, P1

Reviews

9 review(s) available for cyclosporine and Genetic Predisposition

ArticleYear
Vernal keratoconjunctivitis in twins: case report and literature review.
    Italian journal of pediatrics, 2021, Jun-12, Volume: 47, Issue:1

    Topics: Administration, Topical; Child; Cyclosporine; Genetic Predisposition to Disease; Haplotypes; HLA Antigens; Humans; Immunosuppressive Agents; Keratoconjunctivitis; Male; Pedigree; Twins, Monozygotic

2021
Systematic review of cyclosporin A-induced gingival overgrowth and genetic predisposition.
    Quintessence international (Berlin, Germany : 1985), 2017, Volume: 48, Issue:9

    Topics: Cyclosporine; Genetic Predisposition to Disease; Gingival Overgrowth; Humans; Immunosuppressive Agents; Kidney Transplantation

2017
Peripheral neuropathy and gastroenterologic disorders: an overview on an underrecognized association.
    Acta bio-medica : Atenei Parmensis, 2018, 12-17, Volume: 89, Issue:9-S

    Topics: Antibodies, Monoclonal; Antirheumatic Agents; Campylobacter Infections; Celiac Disease; Child; Comorbidity; Cyclosporine; Diet, Gluten-Free; Electrophysiology; Gastrointestinal Diseases; Genetic Predisposition to Disease; Guillain-Barre Syndrome; Humans; Inflammatory Bowel Diseases; Intestinal Pseudo-Obstruction; Malnutrition; Micronutrients; Muscular Dystrophy, Oculopharyngeal; Ophthalmoplegia; Peripheral Nervous System Diseases; Quality of Life; Thalidomide

2018
Autoimmunity in the pathogenesis and treatment of keratoconjunctivitis sicca.
    Current allergy and asthma reports, 2014, Volume: 14, Issue:1

    Topics: Animals; Antigen-Presenting Cells; Apoptosis; Autoantibodies; Autoimmunity; Cyclosporine; Genetic Predisposition to Disease; Humans; Immunity, Cellular; Immunity, Humoral; Keratoconjunctivitis Sicca; Molecular Mimicry; Quinuclidines; Sjogren's Syndrome; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory; Thiophenes

2014
Pharmacogenetics of psoriasis.
    Pharmacogenomics, 2011, Volume: 12, Issue:1

    Topics: Acitretin; Adrenal Cortex Hormones; Antibodies, Monoclonal; Cyclosporine; Genetic Predisposition to Disease; Humans; Methotrexate; Pharmacogenetics; Precision Medicine; Psoriasis

2011
Cytophagic histiocytic panniculitis with haemophagocytosis in a patient with familial multiple lipomatosis and review of the literature.
    Modern rheumatology, 2012, Volume: 22, Issue:1

    Topics: Cyclosporine; Diagnosis, Differential; Family Health; Female; Genetic Predisposition to Disease; Histiocytic Sarcoma; Histiocytosis, Non-Langerhans-Cell; Humans; Lipomatosis, Multiple Symmetrical; Lymphohistiocytosis, Hemophagocytic; Lymphoma, T-Cell; Male; Panniculitis; Pedigree; Treatment Outcome

2012
[Risk factors conditioning the incidence and severity of cyclosporine A-induced gingival overgrowth and methods of prevention].
    Minerva stomatologica, 2004, Volume: 53, Issue:4

    Topics: Adolescent; Adult; Age Factors; Child; Cyclosporine; Female; Genetic Predisposition to Disease; Gingival Hypertrophy; Humans; Immunosuppressive Agents; Incidence; Male; Organ Transplantation; Postoperative Complications; Prevalence; Risk Factors; Sex Factors

2004
[Presentation of cancers in recipients of a solid-organ transplant].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2001, Volume: 21, Issue:6

    Topics: Carcinogens; Cell Transformation, Neoplastic; Cyclosporine; Genetic Predisposition to Disease; Humans; Immunocompromised Host; Immunosuppression Therapy; Incidence; Kidney Transplantation; Lymphoproliferative Disorders; Melanoma; Neoplasm Metastasis; Neoplasms; Neoplasms, Radiation-Induced; Neoplasms, Second Primary; Neoplastic Stem Cells; Oncogenes; Postoperative Complications; Prevalence; Recurrence; Risk; Sarcoma, Kaposi; Skin Neoplasms; Transplantation; Tumor Virus Infections; Ultraviolet Rays

2001
Thrombotic microangiopathies.
    Critical reviews in oncology/hematology, 1991, Volume: 11, Issue:4

    Topics: Adult; Child; Cyclosporine; Endothelium, Vascular; Female; Genetic Predisposition to Disease; Hemolytic-Uremic Syndrome; Humans; Immunosuppressive Agents; Infections; Kidney; Kidney Transplantation; Microcirculation; Neoplasms; Plasma Exchange; Platelet Aggregation Inhibitors; Pregnancy; Pregnancy Complications, Hematologic; Purpura, Thrombotic Thrombocytopenic; Thrombosis

1991

Trials

2 trial(s) available for cyclosporine and Genetic Predisposition

ArticleYear
Exfoliative cutaneous lupus erythematosus in German shorthaired pointer dogs: disease development, progression and evaluation of three immunomodulatory drugs (ciclosporin, hydroxychloroquine, and adalimumab) in a controlled environment.
    Veterinary dermatology, 2010, Volume: 21, Issue:4

    Topics: Adalimumab; Animals; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Cyclosporine; Dog Diseases; Dogs; Fatty Acids; Female; Genetic Predisposition to Disease; Hydroxychloroquine; Lupus Erythematosus, Cutaneous; Male

2010
Impact of cytokine gene polymorphisms on risk and treatment outcomes of aplastic anemia.
    Annals of hematology, 2011, Volume: 90, Issue:5

    Topics: Adult; Alleles; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Female; Genes, Dominant; Genetic Association Studies; Genetic Predisposition to Disease; Haplotypes; Humans; Immunosuppressive Agents; Interferon-gamma; Male; Middle Aged; Models, Genetic; Polymorphism, Single Nucleotide; Republic of Korea; Risk Factors; Transforming Growth Factor beta1

2011

Other Studies

35 other study(ies) available for cyclosporine and Genetic Predisposition

ArticleYear
Clinical and genetic risk factors for new-onset diabetes mellitus after transplantation (NODAT) in major transplant centres in Malaysia.
    BMC nephrology, 2020, 09-07, Volume: 21, Issue:1

    Topics: Adult; Age Factors; Calcineurin Inhibitors; Cyclosporine; Diabetes Mellitus; Female; Genetic Predisposition to Disease; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Interleukin-7 Receptor alpha Subunit; Kidney Failure, Chronic; Kidney Transplantation; Malaysia; Male; Mannose-Binding Lectin; Middle Aged; Polymorphism, Single Nucleotide; Postoperative Complications; Proportional Hazards Models; Risk Factors; Survival Rate; Young Adult

2020
Aplastic anemia in a patient with CVID due to NFKB1 haploinsufficiency.
    Cold Spring Harbor molecular case studies, 2020, Volume: 6, Issue:6

    Topics: Anemia, Aplastic; Benzoates; Bone Marrow; Common Variable Immunodeficiency; Cyclosporine; Exome Sequencing; Female; Genetic Predisposition to Disease; Haploinsufficiency; Humans; Hydrazines; Middle Aged; NF-kappa B; NF-kappa B p50 Subunit; Pyrazoles; Signal Transduction

2020
Hypermethylation of Interferon Regulatory Factor 8 (IRF8) Confers Risk to Vogt-Koyanagi-Harada Disease.
    Scientific reports, 2017, 04-21, Volume: 7, Issue:1

    Topics: Adult; Cells, Cultured; CpG Islands; Cyclosporine; Dendritic Cells; Dexamethasone; DNA Methylation; Down-Regulation; Female; Genetic Predisposition to Disease; Humans; Interferon Regulatory Factors; Male; Middle Aged; Monocytes; Uveomeningoencephalitic Syndrome

2017
FOXP3 rs3761549 polymorphism predicts long-term renal allograft function in patients receiving cyclosporine-based immunosuppressive regimen.
    Gene, 2018, Feb-20, Volume: 644

    Topics: Adult; Cyclosporine; Female; Forkhead Transcription Factors; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glomerular Filtration Rate; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Polymorphism, Single Nucleotide

2018
Outcome of transplantation for acute lymphoblastic leukemia in children with Down syndrome.
    Pediatric blood & cancer, 2014, Volume: 61, Issue:6

    Topics: Adolescent; Adult; Allografts; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cyclosporine; Disease-Free Survival; Down Syndrome; Genetic Predisposition to Disease; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Infant; Kaplan-Meier Estimate; Living Donors; Myeloablative Agonists; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Registries; Remission Induction; Retrospective Studies; Salvage Therapy; Tacrolimus; Transplantation Conditioning; Treatment Outcome; Whole-Body Irradiation

2014
Association of CYP3A4*18B and CYP3A5*3 polymorphism with cyclosporine-related liver injury in Chinese renal transplant recipients.
    International journal of clinical pharmacology and therapeutics, 2014, Volume: 52, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Asian People; Chemical and Drug Induced Liver Injury; Chi-Square Distribution; China; Cyclosporine; Cytochrome P-450 CYP3A; Drug Therapy, Combination; Female; Gene Frequency; Genetic Predisposition to Disease; Humans; Immunosuppressive Agents; Incidence; Kidney Transplantation; Logistic Models; Male; Middle Aged; Odds Ratio; Phenotype; Risk Factors; Time Factors; Young Adult

2014
Is there a genetic predisposition to new-onset diabetes after kidney transplantation?
    Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 2015, Volume: 26, Issue:6

    Topics: Adult; Calcineurin Inhibitors; Cyclosporine; Diabetes Mellitus; Female; Genetic Predisposition to Disease; Graft Rejection; HLA Antigens; Humans; Hyperglycemia; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Tacrolimus

2015
Rapid Response to Cyclosporin A and Favorable Renal Outcome in Nongenetic Versus Genetic Steroid-Resistant Nephrotic Syndrome.
    Clinical journal of the American Society of Nephrology : CJASN, 2016, Feb-05, Volume: 11, Issue:2

    Topics: Adolescent; Austria; Biopsy; Child; Child, Preschool; Cross-Sectional Studies; Cyclosporine; Disease Progression; DNA Mutational Analysis; Female; Genetic Predisposition to Disease; Germany; Humans; Immunosuppressive Agents; Infant; Intracellular Signaling Peptides and Proteins; Kidney; Kidney Failure, Chronic; Longitudinal Studies; Male; Membrane Proteins; Mutation; Nephrotic Syndrome; Phenotype; Recovery of Function; Remission Induction; Risk Factors; Time Factors; Treatment Outcome; WT1 Proteins

2016
Low-Density Lipoprotein Receptor-Dependent and Low-Density Lipoprotein Receptor-Independent Mechanisms of Cyclosporin A-Induced Dyslipidemia.
    Arteriosclerosis, thrombosis, and vascular biology, 2016, Volume: 36, Issue:7

    Topics: Animals; Apolipoprotein C-III; Biomarkers; Cholesterol Esters; Cyclosporine; Disease Models, Animal; Female; Genetic Predisposition to Disease; Hyperlipidemias; Lipid Metabolism; Lipoprotein Lipase; Lipoproteins, HDL; Lipoproteins, IDL; Lipoproteins, VLDL; Liver; Mice, Inbred C57BL; Mice, Knockout; Phenotype; Proprotein Convertase 9; Receptors, LDL; Time Factors; Triolein

2016
Functional characterization of ABCB4 mutations found in progressive familial intrahepatic cholestasis type 3.
    Scientific reports, 2016, 06-03, Volume: 6

    Topics: ATP Binding Cassette Transporter, Subfamily B; Cholestasis, Intrahepatic; Cyclosporine; Gene Expression; Genetic Association Studies; Genetic Predisposition to Disease; HEK293 Cells; Humans; Kinetics; Leupeptins; Macrolides; Mutation, Missense; Paclitaxel; Protein Transport

2016
ABCB4 missense mutations D243A, K435T, G535D, I490T, R545C, and S978P significantly impair the lipid floppase and likely predispose to secondary pathologies in the human population.
    Cellular and molecular life sciences : CMLS, 2017, Volume: 74, Issue:13

    Topics: Adenosine Triphosphatases; Amino Acid Substitution; ATP Binding Cassette Transporter, Subfamily B; Cell Membrane; Cyclosporine; Genetic Predisposition to Disease; Glycosylation; HEK293 Cells; Humans; Intracellular Space; Lipids; Molecular Chaperones; Mutant Proteins; Mutation, Missense; Phosphatidylcholines; Polymorphism, Single Nucleotide; Protein Stability; Protein Transport; Subcellular Fractions

2017
ABCB1 polymorphisms may have a minor effect on ciclosporin blood concentrations in myasthenia gravis patients.
    British journal of clinical pharmacology, 2008, Volume: 66, Issue:2

    Topics: Adolescent; Adult; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Exons; Female; Genes, MDR; Genetic Predisposition to Disease; Genotype; Haplotypes; Humans; Immunosuppressive Agents; Male; Middle Aged; Myasthenia Gravis; Polymorphism, Single Nucleotide; Predictive Value of Tests

2008
Role of cytochrome P450 2C8 and 2J2 genotypes in calcineurin inhibitor-induced chronic kidney disease.
    Pharmacogenetics and genomics, 2008, Volume: 18, Issue:11

    Topics: 8,11,14-Eicosatrienoic Acid; Arachidonic Acid; Aryl Hydrocarbon Hydroxylases; Calcineurin Inhibitors; Cyclosporine; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Demography; Female; Genetic Predisposition to Disease; Genotype; Humans; Incidence; Kidney Failure, Chronic; Kidney Function Tests; Kidney Transplantation; Kinetics; Male; Middle Aged; Tacrolimus; United States

2008
14-Base pair polymorphism of human leukocyte antigen-G as genetic determinant in heart transplantation and cyclosporine therapy monitoring.
    Human immunology, 2009, Volume: 70, Issue:10

    Topics: Adolescent; Adult; Alleles; Alternative Splicing; Base Pairing; Cyclosporine; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Graft Rejection; Heart Transplantation; Histocompatibility Antigens Class I; HLA Antigens; HLA-G Antigens; Humans; Immunosuppressive Agents; Male; Middle Aged; Polymorphism, Genetic

2009
Prevention of severe cutaneous adverse drug reactions: the emerging value of pharmacogenetic screening.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2010, Mar-23, Volume: 182, Issue:5

    Topics: Adult; Alleles; Allopurinol; Anticonvulsants; Asian People; Carbamazepine; China; Cyclosporine; Drug Hypersensitivity; Genetic Predisposition to Disease; Genetic Testing; Gout Suppressants; HLA-B Antigens; Humans; Immunization, Passive; Immunosuppressive Agents; Keratoconjunctivitis; Male; Stevens-Johnson Syndrome; Urethritis

2010
Cyclosporine inhibits a direct interaction between cyclophilins and hepatitis C NS5A.
    PloS one, 2010, Mar-23, Volume: 5, Issue:3

    Topics: Catalytic Domain; Cell Line, Tumor; Cyclophilin A; Cyclophilins; Cyclosporine; Genetic Predisposition to Disease; Genotype; Hepacivirus; Humans; Immunosuppressive Agents; Mutagenesis; Mutation; Protein Binding; Tyrosine; Viral Nonstructural Proteins

2010
Immunosuppression and renal outcome in congenital and pediatric steroid-resistant nephrotic syndrome.
    Clinical journal of the American Society of Nephrology : CJASN, 2010, Volume: 5, Issue:11

    Topics: Adolescent; Child; Child, Preschool; Cyclosporine; Disease Progression; DNA Mutational Analysis; Drug Resistance; Female; Genes, Wilms Tumor; Genetic Predisposition to Disease; Germany; Heredity; Hospitals, Pediatric; Hospitals, University; Humans; Immunosuppressive Agents; Infant; Intracellular Signaling Peptides and Proteins; Kaplan-Meier Estimate; Kidney; Kidney Failure, Chronic; Laminin; Male; Membrane Proteins; Mutation; Nephrotic Syndrome; Patient Selection; Phenotype; Retrospective Studies; Steroids; Time Factors; Treatment Outcome; TRPC Cation Channels; TRPC6 Cation Channel

2010
Genetic and clinical determinants of early, acute calcineurin inhibitor-related nephrotoxicity: results from a kidney transplant consortium.
    Transplantation, 2012, Mar-27, Volume: 93, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcineurin Inhibitors; Cyclosporine; Cytochrome P-450 CYP3A; Female; Follow-Up Studies; Genetic Predisposition to Disease; Genotype; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Polymorphism, Single Nucleotide; Postoperative Complications; Proportional Hazards Models; Prospective Studies; Risk Factors; Tacrolimus; Young Adult

2012
Autoimmune hepatitis: current knowledge.
    Clinics and research in hepatology and gastroenterology, 2012, Volume: 36, Issue:3

    Topics: Antibodies, Antinuclear; Autoantibodies; Autoantigens; Azathioprine; Child; Cyclosporine; Genetic Predisposition to Disease; Glucocorticoids; Hepatitis, Autoimmune; Humans; Immunosuppressive Agents; Liver Transplantation; Muscle, Smooth; Mycophenolic Acid; Prednisone

2012
Predictors of proctocolectomy in children with ulcerative colitis.
    Journal of pediatric gastroenterology and nutrition, 2012, Volume: 55, Issue:5

    Topics: Calcineurin Inhibitors; Child; Colitis, Ulcerative; Cyclosporine; Family; Female; Genetic Predisposition to Disease; Humans; Hypoalbuminemia; Immunosuppressive Agents; Incidence; Male; Proctocolectomy, Restorative; Risk Assessment; Serum Albumin; Tacrolimus; Time Factors; Weight Loss

2012
ABCB1 polymorphisms are associated with cyclosporine-induced nephrotoxicity and gingival hyperplasia in renal transplant recipients.
    European journal of clinical pharmacology, 2013, Volume: 69, Issue:3

    Topics: Adult; Analysis of Variance; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chi-Square Distribution; Cyclosporine; Cytochrome P-450 CYP3A; Drug Monitoring; Female; Gene Frequency; Genetic Predisposition to Disease; Gingival Hyperplasia; Graft Rejection; Graft Survival; Haplotypes; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Linear Models; Logistic Models; Male; Middle Aged; Odds Ratio; Pharmacogenetics; Phenotype; Polymorphism, Genetic; Retrospective Studies; Risk Factors

2013
Genetic polymorphisms in MDR1 and CYP3A4 genes in Asians and the influence of MDR1 haplotypes on cyclosporin disposition in heart transplant recipients.
    Pharmacogenetics, 2003, Volume: 13, Issue:2

    Topics: Administration, Oral; Area Under Curve; Asia; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DNA Primers; Ethnicity; Exons; Gene Frequency; Genes, MDR; Genetic Predisposition to Disease; Haplotypes; Heart Transplantation; Humans; Immunosuppressive Agents; Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Promoter Regions, Genetic

2003
Development of Graves' disease in a patient under immunosuppressive therapy after liver transplantation.
    Journal of endocrinological investigation, 2003, Volume: 26, Issue:3

    Topics: Adolescent; Alleles; Cyclosporine; Genetic Predisposition to Disease; Graves Disease; HLA-DR Antigens; HLA-DRB1 Chains; Humans; Immunosuppressive Agents; Liver Transplantation; Male; Postoperative Care; Prednisone

2003
[Pathogenesis of cyclosporine induced gingival overgrowth].
    Minerva stomatologica, 2003, Volume: 52, Issue:5

    Topics: Adolescent; Adult; Child; Cross-Sectional Studies; Cyclosporine; Extracellular Matrix; Female; Genetic Predisposition to Disease; Gingival Hypertrophy; Gingivitis; Growth Substances; Humans; Immunosuppressive Agents; Male

2003
HIV-1 infection: fooling the gatekeeper.
    Nature medicine, 2003, Volume: 9, Issue:9

    Topics: Animals; Cyclophilin A; Cyclosporine; DNA-(Apurinic or Apyrimidinic Site) Lyase; Genetic Predisposition to Disease; HIV Infections; HIV-1; Humans; Leukemia Virus, Murine; Mice; Primates; Proteins; Retroviridae; Virion

2003
Non-HLA immunogenetic polymorphisms and the risk of complications after allogeneic hemopoietic stem-cell transplantation.
    Transplantation, 2004, Feb-27, Volume: 77, Issue:4

    Topics: Adult; Blood Cells; Bone Marrow Transplantation; Chronic Disease; Cohort Studies; Cyclosporine; Drug Therapy, Combination; fas Receptor; Female; Genetic Predisposition to Disease; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Interleukins; Male; Methotrexate; Middle Aged; Polymorphism, Genetic; Transplantation, Homologous; Tumor Necrosis Factor-alpha

2004
ABCB1 genotype of the donor but not of the recipient is a major risk factor for cyclosporine-related nephrotoxicity after renal transplantation.
    Journal of the American Society of Nephrology : JASN, 2005, Volume: 16, Issue:5

    Topics: Adult; Aged; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Female; Genes, MDR; Genetic Predisposition to Disease; Genotype; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Polymorphism, Genetic; Postoperative Complications; Predictive Value of Tests; Risk Factors; Tissue Donors

2005
Cyclosporin A specifically affects nuclear PLCbeta1 in immunodepressed heart transplant patients with gingival overgrowth.
    Journal of dental research, 2005, Volume: 84, Issue:8

    Topics: Adult; Blotting, Western; Case-Control Studies; Cell Nucleus; Cells, Cultured; Cyclosporine; Enzyme Induction; Fibroblasts; Genetic Predisposition to Disease; Gingiva; Gingival Overgrowth; Heart Transplantation; Humans; Immunosuppressive Agents; Isoenzymes; Male; Microscopy, Electron, Transmission; Middle Aged; Phospholipase C beta; Statistics, Nonparametric; Type C Phospholipases

2005
A model of prediction system for adverse cardiovascular reactions by calcineurin inhibitors among patients with renal transplants using gene-based single-nucleotide polymorphisms.
    Journal of human genetics, 2005, Volume: 50, Issue:9

    Topics: Calcineurin Inhibitors; Cardiovascular Diseases; Case-Control Studies; Cyclosporine; Genetic Predisposition to Disease; Genetic Variation; Humans; Kidney Transplantation; Pharmacogenetics; Polymorphism, Single Nucleotide; Prognosis; Risk Factors; Tacrolimus

2005
Relationship between IL-1A polymorphisms and gingival overgrowth in renal transplant recipients receiving Cyclosporin A.
    Journal of clinical periodontology, 2006, Volume: 33, Issue:11

    Topics: Adult; Age Factors; Alleles; Cyclosporine; Cytosine; Female; Genetic Predisposition to Disease; Genotype; Gingival Crevicular Fluid; Gingival Hyperplasia; Humans; Immunosuppressive Agents; Interleukin-1alpha; Interleukin-1beta; Interleukin-6; Interleukin-8; Kidney Transplantation; Male; Polymorphism, Genetic; Risk Factors; Thymine

2006
Autoimmune hepatitis: are we using the right therapy?
    Journal of pediatric gastroenterology and nutrition, 2007, Volume: 44, Issue:1

    Topics: Adolescent; Animals; Azathioprine; Child; Cyclosporine; Disease Models, Animal; Genetic Predisposition to Disease; Glucocorticoids; Hepatitis, Autoimmune; Humans; Immunosuppressive Agents; Mice; Tacrolimus

2007
Identification of a specific HLA class II haplotype strongly associated with susceptibility to cyclosporine-dependent aplastic anemia.
    Blood, 1994, Dec-15, Volume: 84, Issue:12

    Topics: Adolescent; Adult; Aged; Alleles; Anemia, Aplastic; Autoimmune Diseases; Cyclosporine; Female; Genes, MHC Class II; Genetic Predisposition to Disease; Haplotypes; HLA-DQ alpha-Chains; HLA-DQ Antigens; HLA-DQ beta-Chains; HLA-DR Antigens; HLA-DRB1 Chains; Humans; Incidence; Japan; Male; Middle Aged; Polymorphism, Single-Stranded Conformational; Recurrence; Remission Induction

1994
[Findings in children with psoriasis].
    Nederlands tijdschrift voor geneeskunde, 1999, Jan-16, Volume: 143, Issue:3

    Topics: Adolescent; Adrenal Cortex Hormones; Anthralin; Anti-Inflammatory Agents; Aspirin; Calcitriol; Child; Cyclosporine; Dermatologic Agents; Female; Genetic Predisposition to Disease; Humans; Male; Phototherapy; Psoriasis; Retrospective Studies; Tars; Treatment Outcome; Tretinoin

1999
High level calcineurin activity predisposes neuronal cells to apoptosis.
    The Journal of biological chemistry, 1999, Nov-26, Volume: 274, Issue:48

    Topics: Adenoviruses, Human; Animals; Apoptosis; Calcimycin; Calcineurin; Calcium; Caspase 3; Caspases; Cell Line; Cerebral Cortex; Cyclosporine; Cysteine Proteinase Inhibitors; Enzyme Activation; Gene Expression; Genetic Predisposition to Disease; Humans; Ionophores; L-Lactate Dehydrogenase; Nerve Growth Factor; Neurons; PC12 Cells; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Recombinant Fusion Proteins; Serpins; Tacrolimus; Transfection; Viral Proteins

1999
Genetic factors play an important role in the pathogenesis of hyperlipidemia post-transplantation.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2002, Volume: 40, Issue:1

    Topics: Adult; Apolipoproteins E; Body Composition; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Contraindications; Cyclosporine; Diet; Female; Genetic Predisposition to Disease; Graft Survival; Humans; Hyperlipidemia, Familial Combined; Hyperlipidemias; Immunosuppressive Agents; Kidney Transplantation; Male; Mexico; Sex Factors; Surveys and Questionnaires

2002