Compounds > cyclosporine

cyclosporine and Colorectal Neoplasms

cyclosporine has been researched along with Colorectal Neoplasms in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (19.05)18.2507
2000's12 (57.14)29.6817
2010's4 (19.05)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Aoyama, RG; Belvin, M; Boggs, J; Choo, EF; Deng, Y; Hoeflich, KP; Johnston, SH; Kassees, R; Ly, J; Martini, JF; Merchant, M; Orr, C; Plise, E; Ramaiya, A; Robarge, K1
Andersson, Y; Dueland, S; Engebraaten, O; Flatmark, K; Fodstad, Ø; Herud, TM; Inderberg, EM; Kvalheim, G1
Arcaroli, JJ; Degregori, JV; Eckhardt, SG; Gregory, MA; Gustafson, DL; Hansen, RJ; Kim, J; Klauck, PJ; McManus, MC; McPhillips, KL; Messersmith, WA; Micel, LN; Newton, TP; Pitts, TM; Selby, HM; Spreafico, A; Tan, AC; Tentler, JJ; Winn, RA1
Blake, D; Bridgewater, J; Brown, S; Chau, I; Gollins, S; Gwyther, S; Hill, M; Lowe, C; Maisey, N; Marshall, H; Maughan, T; Middleton, G; Myint, S; Napp, V; Oliver, A; Richman, S; Seymour, M; Slater, S; Wadsley, J; Wagstaff, J1
Masuo, T; Mori, M; Okamura, S; Zhang, Y1
Dahlem, C; Kollmar, O; Menger, MD; Rupertus, K; Schilling, MK1
Ford, AC; Hanauer, SB; Moayyedi, P1
Agamah, E; Desai, AA; Kindler, HL; Mani, S; Ratain, MJ; Taber, D; Vokes, EE; Wade-Oliver, K1
Huang, CW; Lee, CH; Lee, JC; Lin, CN; Liu, HS; Su, CL; Won, SJ1
Casadio, F; Corti, B; Croci, S; D'Errico Grigioni, A; Grigioni, WF; Landuzzi, L; Lollini, PL1
Anthoney, DA; Jagdev, S; Seymour, MT; Vasudev, NS1
Borel Rinkes, IH; Hoeben, RC; Kranenburg, O; Smakman, N; van den Wollenberg, DJ; van der Bilt, JD1
Cai, SR; Zhang, SZ; Zheng, S1
Lakatos, L; Lakatos, PL1
Guardiola, J; Rodríguez-Moranta, F; Soriano-Izquierdo, A1
Girelli, CM; Rocca, E; Rocca, F; Serio, G1
Harboe, M; Lea, T; Ostenstad, B; Schlichting, E; Sioud, M1
Lémann, M1
Bagshawe, KD; Sharma, SK1
Cohen, D; Uchiyama-Kokubu, N; Watanabe, T1
Chrétien, Y; Nordlinger, B; Panis, Y; Ribeiro, J1

Reviews

3 review(s) available for cyclosporine and Colorectal Neoplasms

ArticleYear
Ulcerative colitis.
    BMJ (Clinical research ed.), 2013, Feb-05, Volume: 346

    Topics: Aminosalicylic Acids; Anti-Inflammatory Agents; Biological Products; Breast Feeding; Colectomy; Colitis, Ulcerative; Colorectal Neoplasms; Cyclosporine; Early Detection of Cancer; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Osteoporosis; Patient Education as Topic; Pregnancy; Pregnancy Complications; Remission Induction; Thionucleosides; Tumor Necrosis Factor-alpha

2013
[Medical therapy of inflammatory bowel diseases: ulcerative colitis].
    Orvosi hetilap, 2007, Jun-24, Volume: 148, Issue:25

    Topics: Administration, Oral; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Azathioprine; Carcinoma; Colitis, Ulcerative; Colorectal Neoplasms; Cyclosporine; Gastrointestinal Agents; Humans; Immunosuppressive Agents; Infliximab; Mesalamine; Severity of Illness Index

2007
[Current status of treatment of inflammatory bowel disease].
    Cirugia espanola, 2007, Volume: 82, Issue:5

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Azathioprine; Certolizumab Pegol; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Colectomy; Colitis, Ulcerative; Colorectal Neoplasms; Controlled Clinical Trials as Topic; Crohn Disease; Cyclosporine; Gastrointestinal Agents; Humans; Immunoglobulin Fab Fragments; Immunosuppressive Agents; Inflammatory Bowel Diseases; Infliximab; Infusions, Intravenous; Mercaptopurine; Meta-Analysis as Topic; Polyethylene Glycols; Quality of Life; Rectal Fistula; Recurrence; Time Factors

2007

Trials

3 trial(s) available for cyclosporine and Colorectal Neoplasms

ArticleYear
Immune stimulatory effect of anti-EpCAM immunotoxin - improved overall survival of metastatic colorectal cancer patients.
    Acta oncologica (Stockholm, Sweden), 2020, Volume: 59, Issue:4

    Topics: Colorectal Neoplasms; Cyclosporine; Epithelial Cell Adhesion Molecule; Humans; Immunoconjugates; Immunosuppressive Agents; Immunotoxins; Neoplasm Metastasis; Prognosis; Survival Rate

2020
A randomised phase III trial of the pharmacokinetic biomodulation of irinotecan using oral ciclosporin in advanced colorectal cancer: results of the Panitumumab, Irinotecan & Ciclosporin in COLOrectal cancer therapy trial (PICCOLO).
    European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:16

    Topics: Administration, Oral; Aged; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Camptothecin; Colorectal Neoplasms; Cyclosporine; Diarrhea; Disease-Free Survival; Drug Administration Schedule; Female; Humans; Irinotecan; Kaplan-Meier Estimate; Male; Middle Aged; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Odds Ratio; Time Factors; Treatment Outcome; United Kingdom

2013
Modulation of irinotecan with cyclosporine: a phase II trial in advanced colorectal cancer.
    Cancer chemotherapy and pharmacology, 2005, Volume: 56, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Camptothecin; Colorectal Neoplasms; Cyclosporine; Drug Interactions; Female; Humans; Immunosuppressive Agents; Irinotecan; Male; Middle Aged

2005

Other Studies

15 other study(ies) available for cyclosporine and Colorectal Neoplasms

ArticleYear
Preclinical disposition of GDC-0973 and prospective and retrospective analysis of human dose and efficacy predictions.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:5

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Autoradiography; Azetidines; Bile; Brain; Cell Line, Tumor; Cell Membrane; Cell Membrane Permeability; Colorectal Neoplasms; Dogs; Dose-Response Relationship, Drug; Female; Humans; Injections, Intravenous; Macaca fascicularis; Male; Mice; Mice, Nude; Microsomes, Liver; Models, Biological; Piperidines; Predictive Value of Tests; Prospective Studies; Protein Kinase Inhibitors; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Retrospective Studies; Species Specificity; Tissue Distribution; Xenograft Model Antitumor Assays

2012
Rational combination of a MEK inhibitor, selumetinib, and the Wnt/calcium pathway modulator, cyclosporin A, in preclinical models of colorectal cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2013, Aug-01, Volume: 19, Issue:15

    Topics: Apoptosis; Benzimidazoles; Calcium; Calcium Signaling; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Cyclosporine; Humans; MAP Kinase Kinase Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); ras Proteins; Signal Transduction; Wnt Signaling Pathway; Xenograft Model Antitumor Assays

2013
Cyclosporine A inhibits colorectal cancer proliferation probably by regulating expression levels of c-Myc, p21(WAF1/CIP1) and proliferating cell nuclear antigen.
    Cancer letters, 2009, Nov-18, Volume: 285, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Calcineurin; Calcineurin Inhibitors; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclooxygenase 2; Cyclosporine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Male; Middle Aged; NFATC Transcription Factors; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-myc; RNA, Messenger; Time Factors; Transforming Growth Factor beta1

2009
Rapamycin inhibits hepatectomy-induced stimulation of metastatic tumor growth by reduction of angiogenesis, microvascular blood perfusion, and tumor cell proliferation.
    Annals of surgical oncology, 2009, Volume: 16, Issue:9

    Topics: Adenocarcinoma; Angiogenesis Inhibitors; Animals; Apoptosis; Cell Cycle; Cell Proliferation; Colorectal Neoplasms; Cyclosporine; Female; Hepatectomy; Humans; Immunoenzyme Techniques; Immunosuppressive Agents; In Situ Nick-End Labeling; Liver Regeneration; Mice; Mice, Inbred BALB C; Mice, Nude; Microcirculation; Neovascularization, Pathologic; Protein Kinases; Sirolimus; TOR Serine-Threonine Kinases; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2009
Justicidin A decreases the level of cytosolic Ku70 leading to apoptosis in human colorectal cancer cells.
    Carcinogenesis, 2005, Volume: 26, Issue:10

    Topics: Animals; Antigens, Nuclear; Apoptosis; bcl-2-Associated X Protein; Cell Cycle; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Cyclosporine; Cytoplasm; Dioxolanes; DNA-Binding Proteins; Female; G1 Phase; Humans; Ku Autoantigen; Lignans; Mice; Mice, Nude; Mitochondria; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Transplantation, Heterologous; Uterine Cervical Neoplasms

2005
Toward the definition of immunosuppressive regimens with antitumor activity.
    Transplantation proceedings, 2005, Volume: 37, Issue:5

    Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Cyclosporine; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Isoxazoles; Jurkat Cells; Leflunomide; Liver Neoplasms; Mycophenolic Acid; Rhabdomyosarcoma; Sirolimus

2005
Intravenous irinotecan plus oral ciclosporin.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2005, Volume: 17, Issue:8

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Cyclosporine; Female; Humans; Infusions, Intravenous; Irinotecan; Male; Middle Aged

2005
Immunosuppression promotes reovirus therapy of colorectal liver metastases.
    Cancer gene therapy, 2006, Volume: 13, Issue:8

    Topics: Animals; Cell Line, Tumor; Colorectal Neoplasms; Combined Modality Therapy; Cyclosporine; Immunosuppressive Agents; Injections, Intralesional; Liver Neoplasms; Mammalian orthoreovirus 3; Mice; Mice, Inbred BALB C; Mutation; Oncolytic Virotherapy; Oncolytic Viruses; Transplantation, Isogeneic; Xenograft Model Antitumor Assays

2006
Clinical features of familial adenomas polyps in Chinese and establishment of its immortal lymphocyte cell lines.
    World journal of gastroenterology, 2007, May-28, Volume: 13, Issue:20

    Topics: Adenomatous Polyposis Coli; Adenomatous Polyposis Coli Protein; Adult; Aged; Cell Line; China; Colorectal Neoplasms; Cyclosporine; Disease Progression; Enzyme Inhibitors; Female; Genotype; Humans; Lymphocytes; Male; Middle Aged; Mutation; Pedigree; Risk Factors

2007
Refractory ulcerative colitis and iatrogenic colorectal Kaposi's sarcoma.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2009, Volume: 41, Issue:2

    Topics: Adult; Colectomy; Colitis, Ulcerative; Colon; Colorectal Neoplasms; Cyclosporine; Glucocorticoids; Humans; Iatrogenic Disease; Immunosuppression Therapy; Immunosuppressive Agents; Male; Prednisone; Sarcoma, Kaposi

2009
Freshly isolated tumour-infiltrating T-lymphocytes have a high cytotoxic potential, as measured by their ability to induce apoptosis in the target cell.
    Scandinavian journal of immunology, 1995, Volume: 41, Issue:1

    Topics: Adenocarcinoma; Apoptosis; CD3 Complex; Colorectal Neoplasms; Cyclosporine; Cytotoxicity, Immunologic; DNA Damage; Humans; Immunity, Cellular; In Vitro Techniques; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating

1995
[Natural history of treated hemorrhagic rectocolitis].
    Gastroenterologie clinique et biologique, 1996, Volume: 20, Issue:2

    Topics: Adrenal Cortex Hormones; Aminosalicylic Acids; Antirheumatic Agents; Colectomy; Colitis, Ulcerative; Colorectal Neoplasms; Combined Modality Therapy; Cyclosporine; Humans; Recurrence

1996
Cyclosporine delays host immune response to antibody enzyme conjugate in ADEPT.
    Transplantation proceedings, 1996, Volume: 28, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Antibodies, Monoclonal; Antibody Formation; Colonic Neoplasms; Colorectal Neoplasms; Cyclosporine; gamma-Glutamyl Hydrolase; Humans; Immunoglobulin G; Immunoglobulin M; Immunosuppressive Agents; Immunotherapy; Middle Aged; Pilot Projects; Prodrugs; Rectal Neoplasms

1996
Intracellular levels of two cyclosporin derivatives valspodar (PSC 833) and cyclosporin a closely associated with multidrug resistance-modulating activity in sublines of human colorectal adenocarcinoma HCT-15.
    Japanese journal of cancer research : Gann, 2001, Volume: 92, Issue:10

    Topics: Adenocarcinoma; Anticarcinogenic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Division; Colorectal Neoplasms; Cyclosporine; Cyclosporins; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Humans; Inhibitory Concentration 50; Intracellular Fluid; Rhodamine 123; Tumor Cells, Cultured; Verapamil

2001
Dormant liver metastases: an experimental study.
    The British journal of surgery, 1992, Volume: 79, Issue:3

    Topics: Animals; Cell Line; Colorectal Neoplasms; Cyclosporine; Hepatectomy; Liver Neoplasms; Male; Neoplasm Recurrence, Local; Neoplasm Transplantation; Rats; Rats, Inbred Strains; Time Factors

1992