cyclosporine has been researched along with Cirrhosis in 213 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 48 (22.54) | 18.2507 |
| 2000's | 95 (44.60) | 29.6817 |
| 2010's | 60 (28.17) | 24.3611 |
| 2020's | 10 (4.69) | 2.80 |
| Authors | Studies |
|---|---|
| Cui, Y; Fang, J; Guo, C; Hu, W; Song, B; Xia, M; Xia, Z; Xu, D; Xue, Y; Zhang, C; Zhang, S | 1 |
| Du, H; Hou, L; Huang, K; Le, G; Liu, S; Mao, X | 1 |
| Bayrami, A; Naderi, R; Nourmohammadi, K; Shirpoor, A | 1 |
| Abe, M; Endo, M; Fukuda, N; Horikoshi, S; Inoue, T; Mineshige, T; Otsuki, M; Otsuki, T | 1 |
| Liu, B; Tan, P | 1 |
| Dihazi, GH; Dihazi, H; Eltoweissy, M; Jahn, O; Müller, GA; Tampe, B; Wülfrath, HS; Zeisberg, M | 1 |
| Borràs, FE; Cañas, L; Carreras-Planella, L; Franquesa, M; Juega, J; Lauzurica, R; Taco, O | 1 |
| Ahmed, RM; Maamoun, H; Soliman, AR; Soliman, H | 1 |
| Bai, Y; Cai, H; Cheriyan, AM; Francis, CE; Gooch, JL; Hoover, RS; King, KN; Linck, VA; Ma, HP; Ume, AC; Williams, CR | 1 |
| Barzaghi, F; Carletti, R; Castoldi, G; Colzani, M; di Gioia, CRT; Ippolito, S; Perseghin, G; Stella, A; Zatti, G; Zerbini, G | 1 |
| Chou, ASY; Gill, A; Jarolimek, W; Nguyen, LT; Pollock, CA; Saad, S; Shi, Y; Wang, R; Yao, Y | 1 |
| Ando, T; Hamada, R; Hamasaki, Y; Hataya, H; Honda, M; Ishikura, K; Komaki, F; Ogata, K; Sakai, T | 1 |
| DeLuca, H; Hullett, D; Larson-Osborne, A; O'Brien, C; Plum, L; Sollinger, H; Tomasini-Johansson, B; Toraason, I | 1 |
| Chang, YS; Chung, S; Hong, YA; Kim, HS; Kim, M; Kim, S; Koh, ES; Park, CW; Shin, SJ | 1 |
| Chen, W; Chi, J; Fu, Y; Liu, W; Liu, Y; Shi, Z; Wang, L; Yin, X; Zhang, X | 1 |
| Alkhansa, S; Eid, AA; El-Mas, MM; Hammoud, SH; Mahjoub, N; Omar, AG | 1 |
| Morinobu, A; Onishi, A; Saegusa, J; Shirai, T; Waki, D | 1 |
| Eberhardt, W; Nasrullah, U; Pfeilschifter, J | 1 |
| Akool, ES; Balah, A; Ezzat, O | 1 |
| Fujino, M; Isaka, Y; Ito, H; Li, XK; Liu, C; Nakajima, M; Takahashi, K; Tanaka, T; Zhu, P; Zhuang, J | 1 |
| Agellon, LB; Alexander, RT; Chen, XZ; Groenendyk, J; Hu, M; Mengel, M; Michalak, M; Robinson, A; Tang, J; Wang, Q | 1 |
| Huang, YX; Li, Y; Liang, S; Lin, CX; Liu, SY; Su, YF; Tao, J; Zhang, LS; Zhao, ZK; Zheng, JM | 1 |
| Chen, Y; Hu, G; Li, Q; Peng, Z; Qin, J; Tao, L; Wang, N; Xie, Y; Yuan, Q | 1 |
| Duvoux, C; Firpi, R; Grazi, GL; Levy, G; Renner, E; Villamil, F | 1 |
| Bie, P; Hansen, PB; Jensen, BL; Marcussen, N; Nielsen, FT | 1 |
| Chung, BH; Doh, KC; Heo, SB; Lim, SW; Piao, SG; Yang, CW | 1 |
| Bayle, F; Girardot-Seguin, S; Heng, AE; Hertig, A; Hurault de Ligny, B; Jauréguy, M; Le Meur, Y; Le Pogamp, P; Lebranchu, Y; Meas-Yedid, V; Rondeau, E; Servais, A; Thervet, E; Touchard, G; Toupance, O; Xu-Dubois, YC | 1 |
| Fan, Y; Liu, A; Liu, F; Nicholson, ML; Shi, L; Wu, Y; Yang, B; Yang, C; Zhang, J; Zhang, Y; Zhu, T | 1 |
| Ali, RM; El-Gowelli, HM; El-Mas, MM; Helmy, MW | 2 |
| Chang, YS; Choi, BS; Chung, S; Hong, YA; Kim, EN; Kim, MY; Koh, ES; Lim, JH; Park, CW; Shin, SJ | 1 |
| Ganguly, B; Hsieh, S; Kulbokas, EJ; Latek, R; Sarwal, MM; Townsend, R; Vitalone, MJ | 1 |
| Meseguer, A; Moreso, F; Sarró, E; Serón, D; Torres, IB | 1 |
| Savikko, J; Taskinen, E; Teppo, AM; von Willebrand, E | 1 |
| Andersson, H; Bistrup, C; Gustafsson, B; Hansen, JM; Holdaas, H; Jespersen, B; Mjörnstedt, L; Schwartz Sørensen, S; Solbu, D; von Zur Mühlen, B | 1 |
| Borda, B; Kemény, E; Keresztes, C; Kubik, A; Lázár, G; Lengyel, C; Ottlakán, A; Várkonyi, T | 1 |
| Chen, J; Mannon, RB; Zhi, D; Zmijewska, A | 1 |
| Chen, YP; Li, M; Rui, HL; Sun, QL | 1 |
| Albano, L; Anglicheau, D; Di Giambattista, F; Dubois, YC; Durrbach, A; Hazzan, M; Hertig, A; Hurault deLigny, B; Lang, P; Merville, P; Moulin, B; Quéré, S; Rondeau, E; Rostaing, L; Touchard, G; Vuiblet, V | 1 |
| Balicza-Himer, L; Boros, S; Csohány, R; Fekete, A; Kis-Petik, K; Magda, B; Pap, D; Peti-Peterdi, J; Prókai, Á; Szabó, AJ; Sziksz, E; Vannay, Á | 1 |
| Choi, BS; Jin, DC; Kim, EN; Kim, HW; Kim, MY; Lim, JH; Park, CW; Park, HS; Yang, CW | 1 |
| Attia, GM; Nader, MA | 1 |
| Dai, Z; Hong, J; Liu, X; Sun, J; Sun, X; Yu, X | 1 |
| Hu, Y; Lin, W; Mou, L; Tu, H; Yang, F | 1 |
| Cannata-Ortiz, P; Egido, J; González-Guerrero, C; Guerri, C; Ortiz, A; Ramos, AM | 1 |
| Gao, BS; Lian, X; Sun, WX; Wang, WG; Zhou, HL | 1 |
| Fujikawa, K; Harada, K; Ito, M; Iwanaga, N; Izumi, Y; Kawahara, C; Kawakami, A; Kurohama, K; Migita, K; Tsuji, Y; Yoshida, S | 1 |
| Ajitkumar, S; Murugan Girija, D; Ranga Rao, S; Subbarayan, R | 1 |
| Berce, C; Berindan-Neagoe, I; Bojan, A; Ciurea, SO; Dima, D; Frinc, I; Gafencu, G; Ghiaur, G; Jurj, A; Magdo, L; Pasca, S; Petrushev, B; Pop, L; Rosu, AM; Selicean, S; Tanase, A; Tomuleasa, C; Trifa, A; Zdrenghea, M | 1 |
| Akool, el-S; Babelova, A; Doller, A; Eberhardt, W; Moreth, K; Pfeilschifter, J; Schaefer, L; Tsalastra, W | 1 |
| Currin, RT; Giri, S; Kim, I; Lemasters, JJ; Ramshesh, VK; Rehman, H; Theruvath, TP; Zhong, Z | 1 |
| Jiang, D; Song, G; Wang, X; Xu, J; Zhang, J | 1 |
| Glowacki, F; Hazzan, M; Lionet, A; Noël, C; Provot, F | 1 |
| Hong, SW; Jeong, HJ; Kim, JH; Lim, BJ | 1 |
| Bouda, M; Hes, O; Jindra, P; Kormunda, S; Reischig, T; Treska, V | 1 |
| Bonomini, F; Lavazza, A; Rezzani, R; Rodella, LF; Stacchiotti, A | 1 |
| Bemelman, FJ; de Fijter, HW; de Maar, EF; Homan van der Heide, JJ; Press, RR; ten Berge, IJ; van Kan, HJ | 1 |
| Fujinaga, S; Hara, S; Murakami, H; Ohtomo, Y; Shimizu, T; Someya, T; Umino, D | 1 |
| Doganavsargil, E; Kobak, S; Oksel, F; Savas, R | 1 |
| Denzel, A; Göbel, N; Mack, M; Niedermeier, M; Reich, B; Rodriguez Gomez, M; Schmidbauer, K; Schweda, F; Talke, Y | 1 |
| Etienne, I; Glotz, D; Hayem, C; Hurault, de LB; Le Meur, Y; Le Pogamp, P; Lebranchu, Y; Meas-Yedid, V; Moulin, B; Olivo Marin, JC; Presne, C; Servais, A; Thervet, E; Thierry, A; Toupance, O | 1 |
| Katsuta, O; Nakagawa, S; Nakamura, M; Oda, T; Shii, D; Shinomiya, K; Yoshimi, M | 1 |
| Bai, Y; Hu, L; Jin, Y; Li, S; Liu, Q; Luo, Z; Tao, Y; Wei, D | 1 |
| He, F; Luo, ZM; Ma, L; Tong, JR; Wang, Y | 2 |
| Choi, HG; Jung, KA; Kang, KW; Kensler, TW; Kim, DD; Kim, JA; Kim, SG; Ku, SK; Kwak, MK; Park, HM; Shin, DH | 1 |
| Bae, EH; Choi, C; Kim, IJ; Kim, SW; Lee, J; Ma, SK; Park, JW | 1 |
| Ghee, JY; Han, DH; Kim, J; Lee, SY; Piao, SG; Song, HK; Song, JH; Yang, CW; Yoon, HE; Yoon, HJ | 1 |
| Reis, FN | 1 |
| Ancona, N; Dell'Oglio, MP; Ditonno, P; Divella, C; Grandaliano, G; Pontrelli, P; Rossini, M; Rutigliano, M; Schena, FP; Stifanelli, P; Verrienti, R; Zaza, G | 1 |
| Aoudjehane, L; Ben Othman, S; Calmus, Y; Conti, F; Housset, C; Pissaia, A; Scatton, O; Soubrane, O | 1 |
| Brown, D; Chang, M; Flynn, KJ; Jester, JV; Nien, CJ | 1 |
| Wang, X; Wang, XT; Wei, M | 1 |
| Erdal, R; Haberal, M; Özdemir, AA; Özdemir, BH; Özdemir, FN | 1 |
| Alidousty, C; Boor, P; Djudjaj, S; Floege, J; Frye, BC; Hanssen, L; Mertens, PR; Ostendorf, T; Raffetseder, U; Rauen, T | 1 |
| Berrera, M; Bruschi, M; Chaykovska, L; Gabbiani, G; Ghiggeri, G; Hocher, B; Lescuyer, P; Moll, S; Prunotto, M | 1 |
| Anraku, M; Guan, Z; Hirayama, S; Hwang, DM; Keshavjee, S; Liu, M; Sato, M; Waddell, TK; Wagnetz, D; Yeung, JC | 1 |
| Johnson, RJ; Mazali, FC; Mazzali, M | 1 |
| Bishop, JV; Chedwick, LR; Kellum, JA; Li, Y; Peng, Z; Singbartl, K; Wang, H; Wen, X | 1 |
| Abe, T; Ichimaru, N; Imamura, R; Isaka, Y; Kakuta, Y; Nonomura, N; Okumi, M; Okuyama, A; Takahara, S; Tsuda, H; Yazawa, K | 1 |
| Luo, G; Luo, L; Sun, Z | 1 |
| Alfarano, C; Bascands, JL; Calise, D; Ceccaldi, C; Chaaya, R; Cussac, D; Mias, C; Parini, A; Roubeix, C | 1 |
| Alves, SA; Burdmann, EA; Carlos, CP; Coimbra, TM; Luz, MA; Matimoto, RL; Mendes, GE; Oliveira, SM; Souza, RP | 1 |
| Gerolymos, M; Goumenos, DS; Huang, L; Johnson, TS; Kalliakmani, P; Papasotiriou, M | 1 |
| Sun, DY; Wang, X; Wang, XT | 1 |
| Angoscini, P; Bianchi, R; Rezzani, R; Rodella, L | 1 |
| Metcalfe, MS; Murphy, GJ; Nicholson, ML; Pattenden, CJ; Sandford, RM; Waller, JR | 1 |
| Ahn, HJ; Bang, BK; Cha, JH; Kim, J; Kim, WY; Kim, YS; Li, C; Park, CW; Park, JH; Yang, CW | 1 |
| Pescosolido, N; Risuleo, G; Scarsella, G | 1 |
| Dosanjh, A; Ikonen, T; Morris, RE; Wan, B | 1 |
| Ahmed, A; el-Kossi, M; el-Nahas, M; Haylor, J; Raftery, A | 1 |
| Beaufils, H; Deray, G; Isnard Bagnis, C; Jaudon, MC; Jouanneau, C; LeHoang, P; Maksud, P; Mallet, A; Tezenas du Montcel, S | 1 |
| Ahn, HJ; Bang, BK; Cha, JH; Jung, JY; Kim, J; Kim, WY; Kim, YS; Li, C; Yang, CW; Yoon, SA | 1 |
| El Nahas, AM; Gray, C; Haylor, J; Johnson, TS; Raftery, AT; Rawat, S | 1 |
| Chen, D; Gartley, CJ; Harvey, SJ; Jacobs, RM; Jefferson, B; Thorner, PS; Zheng, K | 1 |
| Andreetta, F; Cerletti, M; Colpo, R; Cornelio, F; Cozzi, F; Croci, D; Davies, KE; Gilbert, R; Karpati, G; Mora, M; Negri, T; Pozza, O | 1 |
| Moreno, AJ; Oliveira, PJ; Palmeira, CM; Rolo, AP; Santos, MS; Seiça, R | 1 |
| Bicknell, GR; Murphy, GJ; Nicholson, ML | 1 |
| Bruijn, JA; Claas, FH; de Fijter, JW; Doxiadis, II; Paul, LC; Sijpkens, YW; van Kemenade, FJ; Zwinderman, AH | 1 |
| Furness, PN; Murphy, GJ; Nicholson, ML; Sandford, RS; Waller, JR | 1 |
| Bajema, IM; Bakker, RC; Bruijn, JA; De Heer, E; Eikmans, M; Koop, K; Paul, LC; Sijpkens, YW | 1 |
| Bicknell, GR; Brook, NR; Nicholson, ML; Waller, JR; White, SA | 1 |
| Bang, BK; Jung, JY; Kim, J; Kim, SB; Kim, YS; Li, C; Lim, SW; Park, JH; Sun, BK; Yang, CW | 1 |
| Bicknell, GR; Brook, NR; Nicholson, ML; Waller, JR | 1 |
| Alonso, A; Gómez, JA; Malagelada, JR; Molero, X; Salas, A; Vaquero, E | 1 |
| Bang, BK; Jung, JY; Kim, IS; Kim, J; Kim, YS; Lee, SH; Li, C; Lim, SW; Sun, BK; Yang, CW | 1 |
| Ahmed, A; Ahmed, AK; El Nahas, AM; Fahmy, H; Haylor, JL; Huang, L; Raftery, AT | 1 |
| Andoh, TF; Bennett, WM; Safirstein, R; Saggi, SJ | 1 |
| Homma, T; Ichikawa, I; Imai, E; Isaka, Y; Ma, J; Matsusaka, T; Xin, J | 1 |
| Ehrich, JH; Offner, G; Pape, L | 1 |
| Alho, HS; Maasilta, PK; Päiväniemi, OE; Salminen, US; Wolff, CH | 1 |
| Allegri, L; Bertelli, R; Cancarini, G; Caridi, G; Carrea, A; Catarsi, P; Emma, F; Ghiggeri, GM; Perfumo, F; Rizzoni, GF; Sanna-Cherchi, S; Scolari, F | 1 |
| Hommann, M; Kornberg, A; Küpper, B; Scheele, J; Tannapfel, A | 1 |
| Bianchi, R; Buffoli, B; Giugno, L; Rezzani, R; Rodella, L; Stacchiotti, A | 1 |
| Cho, WY; Jo, SK; Kim, HK; Lee, SY; Won, NH | 1 |
| Abraham, NG; Bianchi, R; Buffoli, B; Goodman, AA; Lianos, EA; Rezzani, R; Rodella, L | 1 |
| Andreetta, F; Arnoldi, E; Burdi, R; Camerino, C; Confalonieri, P; Conte Camerino, D; Courdier-Fruh, I; De Luca, A; Didonna, MP; Fraysse, B; Frigeri, A; Liantonio, A; Magyar, JP; Mangieri, D; Nico, B; Pierno, S; Pisoni, M; Rolland, JF; Svelto, M; Zallone, A | 1 |
| Bukiej, A; Dropiński, J; Dyduch, G; Szczeklik, A | 1 |
| Cha, JH; Kang, DH; Kang, SW; Kim, J; Kim, YS; Li, C; Lim, SW; Song, JC; Sun, BK; Yang, CW | 1 |
| Andriantsitohaina, R; Bianchi, R; Buffoli, B; Giugno, L; Kojsová, S; Pechánová, O; Rezzani, R | 1 |
| de Las Heras-Castaño, G; Domínguez-Diez, A; Fernández-Fernández, F; Fernández-González, MD; García-de la Paz, AM; García-Unzueta, MT; Mayorga-Fernández, M | 1 |
| Campbell, E; Gaffney, MM; McMorrow, T; Ryan, MP; Slattery, C | 1 |
| Campbell, E; McMorrow, T; Ryan, MP; Slattery, C | 1 |
| Barthen, ER; Chan, WY; de Wolff-Rouendaal, D; Emmanouilidis-van der Spek, K; Jager, MJ; Jovanovik-Pandova, L; Liu, C; Watson, PG | 1 |
| Becker, BN; Hullett, DA; Laeseke, PF; Malin, G; Nessel, R; Sollinger, HW | 1 |
| Ashra, SY; Bowley, L; Imtiaz, S; Jain, S; Nicholson, ML; Pawluczyk, IZ; Yang, B | 1 |
| Brunati, A; Cerutti, E; David, E; Franchello, A; Gennari, F; Lavezzo, B; Lupo, F; Marzano, A; Ottobrelli, A; Ricchiuti, A; Rizzetto, M; Romagnoli, R; Salizzoni, M; Schellino, MM; Strignano, P; Zamboni, F | 1 |
| Bajema, IM; Bemelman, F; de Fijter, JW; Eikmans, M; Florquin, S; Idu, M; Mallat, MJ; Paul, LC; Roos-van Groningen, MC; Rowshani, AT; Scholten, EM; Surachno, JS; ten Berge, I; van Groningen, MC | 1 |
| Ahn, KO; Bang, BK; Choi, BS; Kim, J; Kim, JS; Kim, JY; Kim, YS; Li, C; Lim, SW; Yang, CW; Yang, HJ | 1 |
| Baelde, HJ; Bajema, IM; Bemelman, FJ; Bruijn, JA; de Fijter, JW; de Heer, E; Eikmans, M; Florquin, S; Lelieveld, PM; Roos-van Groningen, MC; Rowshani, AT; Scholten, EM | 1 |
| Furst, DE; Georges, GE; Henstorf, G; Langston, AA; Lee, J; McSweeney, PA; Nash, RA; Nelson, JL; Shulman, H; Storb, R; Sullivan, KM; Wener, M | 1 |
| McMorrow, T; Ryan, MP; Slattery, C | 2 |
| Blanco, JA; Bobadilla, NA; Bonventre, JV; Cruz, C; Gamba, G; Pérez-Rojas, J; Trujillo, J; Uribe, N; Vaidya, VS | 1 |
| Bajema, IM; Bemelman, FJ; Cremers, S; de Fijter, JW; Eikmans, M; Florquin, S; Mallat, MJ; Rowshani, AT; Scholten, EM; Surachno, J; ten Berge, IJ; van Kan, E | 1 |
| Bu, H; Li, Q; Qiu, J; Shi, Y; Tu, Z; Wang, J; Wang, W; Ye, F; Zhang, L | 1 |
| Abraham, JL; Boyd, AS; Zic, JA | 1 |
| Ishikawa, A; Kitamura, T; Ohta, N; Ozono, S; Tanaka, M | 1 |
| Ardehali, A; Belperio, JA; Burdick, MD; Gomperts, BN; Grusby, MJ; Hogaboam, C; Keane, MP; Kunkel, SL; Lukacs, NW; Lynch, JP; Nakamura, H; Ross, DJ; Saggar, R; Strieter, RM; Weigt, S; Xue, YY; Zisman, DA | 1 |
| Allen, RD; Borrows, RJ; Chapman, JR; Fung, CL; Nankivell, BJ; O'Connell, PJ; Vitalone, M; Wavamunno, MD | 1 |
| Cukur, S; Dosoglu, M; Gezen, F; Is, M; Yildiz, KH | 1 |
| Gu, M; Liu, M; Wu, Y; Yin, C; Zhang, W; Zhu, P | 1 |
| Akcay, A; Bayrak, R; Karanfil, A; Kaya, A; Ozkara, A; Sahin, S; Selcoki, Y; Uz, B; Uz, E | 1 |
| Cheng, JH; Deng, QG; French, BA; French, SW; Gukovsky, I; Hong, PP; Jung, YJ; Lugea, A; Lungo, W; Pandol, SJ; Shahsahebi, M; Tsukamoto, H | 1 |
| Buchler, M; Meas-Yedid, V; Morelon, E; Olivo-Marin, JC; Servais, A; Thervet, E | 1 |
| Aten, J; de Boer, OJ; de Waart, DR; Hajji, N; Krediet, RT; Kunne, C; van Westrhenen, R | 1 |
| Alperovich, G; Cruzado, JM; Franquesa, Ml; Giménez-Bonafé, P; Grinyó, JM; Herrero-Fresneda, I; Lloberas, N; Rama, I; Torras, J | 1 |
| Chang, HL; Fu, E; Nieh, S; Wang, SL | 1 |
| Alpers, CE; Andoh, T; Bennett, WM; Burdmann, EA; Couser, WG; Eng, E; Giachelli, CM; Johnson, RJ; Young, BA | 1 |
| Fioretto, P; Mauer, M; Mihatsch, MJ; Steffes, MW; Strøm, EH; Sutherland, DE | 1 |
| Irintchev, A; Lange, G; Wernig, A | 1 |
| Fogo, A; Hunley, TE; Kon, V | 1 |
| Demetris, AJ; Jordan, ML; Randhawa, PS; Shapiro, R; Starzl, TE | 1 |
| Holmberg, C; Jalanko, H; Krogerus, L; Laine, J; Rönnholm, K | 1 |
| Ellis, CN; Fradin, MS; Groisser, DS; Hamilton, TA; Johnson, KJ; Leichtman, AB; Messana, JM; Mihatsch, MJ; Voorhees, JJ; Young, EW | 1 |
| Azuma, H; Binder, J; Heemann, U; Tilney, NL; Tullius, SG | 1 |
| Alpers, CE; Andoh, TF; Bennett, WM; Burdmann, EA; Couser, W; Evans, A; Johnson, RJ; Lindsley, J; Young, B | 1 |
| Bell, PR; Donnelly, PK; Feehally, J; Furness, PN; Harper, SJ; McCulloch, TA; Moorhouse, J; Walls, J | 1 |
| Budihna, NV; Kajtna-Koselj, M; Malovrh, M; Milcinski, M | 1 |
| Colomb, V; De Potter, S; Francois, B; Goulet, OJ; Gubler, MC; Jan, D; Kassis, B; Revillon, Y; Ricour, C; Sarnacki, S | 1 |
| Solez, K | 1 |
| Frost, L; Heickendorff, L; Madsen, JK; Pedersen, EB | 1 |
| Antonovych, T; Bohman, SO; Feutren, G; Habib, R; Helmchen, U; Kemény, E; Mihatsch, MJ; Noel, LH; Olsen, S; Sibley, RK | 1 |
| Berg, KJ; Førre, O; Hovig, T; Kvien, TK; Sund, S | 1 |
| Assan, R; Bach, JF; Boitard, C; Bougnères, P; Czernichow, P; Feutren, G; Hannedouche, T; Mihatsch, MJ; Noel, LH; Timsit, J | 1 |
| Andoh, TF; Bennett, WM; Burdmann, EA; Elzinga, LW; Lindsley, J; Munar, MY; Rosen, S | 1 |
| Kähäri, VM | 1 |
| Beckingham, IJ; Blamey, RW; Dennis, MJ | 1 |
| Büttemeyer, R; Jones, NF; Min, Z; Rao, U | 1 |
| Andoh, TF; Bennett, WM; Border, WA; Franceschini, N; Noble, NA; Shihab, FS; Tanner, AM | 1 |
| Kim, DM; Park, KH; Youn, DH | 1 |
| Duraj, FF; Jacobson, SH; Jaremko, G; Wilczek, HE | 1 |
| Bustos, C; Egido, J; González-Cuadrado, S; Guijarro, C; Ortiz, A; Plaza, JJ; Ruiz-Ortega, M | 1 |
| Benkerrou, M; de Graeff-Meeder, BR; Fischer, A; Haddad, E; Patey, N; Spliet, WG; Wulffraat, NM | 1 |
| Alpers, C; Andoh, TF; Bennett, WM; Franceschini, N; Lindsley, J | 1 |
| Andoh, TF; Bennett, WM; Shihab, FS; Tanner, AM | 1 |
| Campbell, JL; Zug, KA | 1 |
| Harjula, AL; Ikonen, T; Morris, RE; Salminen, US; Taskinen, E; Uusitalo, M | 1 |
| Andoh, TF; Bennett, WM; Gardner, MP | 1 |
| Khocht, A; Schneider, LC | 1 |
| Andoh, TF; Bennett, WM; Couser, WG; Johnson, RJ; Pichler, RH; Shankland, SJ; Thomas, SE | 1 |
| Hansen, HE; Kragballe, K; Marcussen, N; Olsen, S; Zachariae, H | 1 |
| Aguilar, M; Arrebola, F; Asensio, C; Becerra, P; Carvia, R; Del Moral, RG; Guillén, M; O'Valle, F; Olmo, A; Osuna, A; Reguero, ME | 1 |
| Bishop, P; el-Gamel, A; Hutchinson, IV; Yonan, NA | 1 |
| Gentile, S; Torella, R; Turco, S | 1 |
| Bajwa, RS; Bunchman, TE; Gregory, MJ; Johnson, KJ; Smoyer, WE | 1 |
| Abrass, CK; Alpers, CE; Berfield, AK; Davis, CL; Stehman-Breen, C | 1 |
| Field, MJ; Huq, SO; Johnson, DW; Johnson, FJ; Pollock, CA; Saunders, HJ | 1 |
| Malagelada, JR; Molero, X; Salas, A; Tian, X; Vaquero, E | 1 |
| Corless, CL; Loomis, CB; Orloff, SL; Rabkin, JM; Wagner, CR; Yin, Q | 1 |
| Andoh, TF; Bennett, WM; Shihab, FS; Tanner, AM; Yi, H | 1 |
| Burdmann, EA; Malheiros, DM; Noronha, IL; Vieira, JM | 1 |
| Benito, MJ; Egido, J; Hernández, P; Herrero-Beaumont, G; López-Armada, MJ; Palacios, I; Sánchez-Pernaute, O | 1 |
| Bicknell, GR; Doughman, T; Furness, P; Jain, S; Nicholson, ML; White, SA; Williams, ST | 1 |
| Browne, R; Nolde-Hurlbert, B; Prashner, H; Seikaly, MG | 1 |
| Attramadal, H; Bjørnerheim, R; Clausen, OP; Oie, E | 1 |
| Bennett, WM; Burdmann, EA; Elzinga, LW; Hatton, DC; Lindsley, J; Rosen, S | 1 |
| Mathieson, PW | 1 |
| Andoh, TF; Bennett, WM; Shihab, FS; Yi, H | 1 |
| Bicknell, GR; Jain, S; Nicholson, ML | 1 |
| Bicknell, GR; Furness, PN; Nicholson, ML; Pringle, JH; Shaw, JA; Williams, ST | 1 |
| Asai, K; Bishop, SP; Hong, C; Karoor, VL; Meguro, T; Sadoshima, J; Takagi, G; Vatner, DE; Vatner, SF; Yang, G | 1 |
| Firatli, E; Hong, HH; Kantarci, A; Sheff, MC; Trackman, PC; Uygur, C; Uzel, MI | 1 |
| Ahn, HJ; Bang, BK; Kim, J; Kim, SK; Kim, WY; Kim, YO; Kim, YS; Park, JH; Shin, MJ; Yang, CW | 1 |
| Hori, M; Imai, E; Kokado, Y; Kyo, M; Moriyama, T; Oka, K; Okuyama, A; Takahara, S; Tanaka, T; Toki, K | 1 |
| Demura, M; Mabuchi, H; Takeda, Y; Usukura, M; Yoneda, T | 1 |
| Baboolal, K; Griffiths, DR; Janezic, A; Jones, GA; Jurewicz, WA | 1 |
| Ganesan, V; Hulton, SA; Milford, DV; Parvaresh, S; Ramani, P; Taylor, CM | 1 |
| Hricik, DE; Robinson, AV; Schulak, JA; Simonson, MS | 1 |
| Alpers, CE; Couser, WG; Dantas, M; Giachelli, CM; Hughes, J; Johnson, RJ; Lan, HY; Liaw, L; Mazzali, M; Pichler, RH; Shankland, SJ; Steitz, S | 1 |
| Hansen, HE; Olsen, TS; Zachariae, H | 1 |
| Bennett, WM; Elzinga, LW; Porter, GA; Rosen, S | 1 |
| Hansen, HE; Kragballe, K; Olsen, S; Zachariae, H | 1 |
10 review(s) available for cyclosporine and Cirrhosis
| Article | Year |
|---|---|
Successful treatment with tacrolimus in TAFRO syndrome: two case reports and literature review.
Topics: Adolescent; Aged; Bone Marrow; Calcineurin Inhibitors; Cardiomyopathies; Castleman Disease; Cyclosporine; Edema; Female; Fever; Fibrosis; Glucocorticoids; Hepatomegaly; Humans; Interleukin-6; Male; Primary Myelofibrosis; Renal Insufficiency; Splenomegaly; Syndrome; Tacrolimus; Thrombocytopenia; Treatment Outcome | 2018 |
Activation of renal profibrotic TGFβ controlled signaling cascades by calcineurin and mTOR inhibitors.
Topics: Animals; Calcineurin; Calcineurin Inhibitors; Cyclosporine; Fibrosis; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Models, Animal; Reactive Oxygen Species; Signal Transduction; Sirolimus; Tacrolimus; TOR Serine-Threonine Kinases; Transforming Growth Factor beta | 2018 |
Recurrent hepatitis C virus infection post liver transplantation: impact of choice of calcineurin inhibitor.
Topics: Calcineurin Inhibitors; Cyclosporine; Diabetes Mellitus; Fibrosis; Graft Rejection; Hepatitis C; Humans; Immunosuppressive Agents; Insulin Resistance; Liver Transplantation; Recurrence; Virus Replication | 2013 |
The Interplay between inflammation and fibrosis in kidney transplantation.
Topics: Cyclosporine; Fibrosis; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Inflammation; Kidney Transplantation; Tacrolimus | 2014 |
Cell Cycle Arrest as a Therapeutic Target of Acute Kidney Injury.
Topics: Acute Kidney Injury; Animals; Autocrine Communication; Biomarkers; Cyclosporine; Epithelial Cells; Fibroblasts; Fibrosis; G1 Phase Cell Cycle Checkpoints; Gene Expression; Humans; Insulin-Like Growth Factor Binding Proteins; Kidney Tubules; Molecular Targeted Therapy; Paracrine Communication; Pericytes; Tissue Inhibitor of Metalloproteinase-2 | 2017 |
[Immunosuppressive strategies and chronic graft dysfunction in kidney transplantation].
Topics: Calcineurin Inhibitors; Cyclosporine; Fibrosis; Follow-Up Studies; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Kidney Transplantation; Kidney Tubular Necrosis, Acute; Mycophenolic Acid; Patient Selection; Primary Graft Dysfunction; Randomized Controlled Trials as Topic; Risk | 2008 |
The unsolved cyclosporine-induced kidney injury: is paricalcitol a feasible new renoprotective option?
Topics: Bone Density Conservation Agents; Cyclosporine; Ergocalciferols; Fibrosis; Humans; Kidney Diseases; Kidney Transplantation; Protective Agents | 2010 |
Renal fibrosis and proteomics: current knowledge and still key open questions for proteomic investigation.
Topics: Animals; Blood Glucose; Cyclosporine; Diabetic Nephropathies; Fibrosis; Glomerulonephritis; Humans; Hypoxia; Kidney; Kidney Diseases; Kidney Failure, Chronic; Proteomics; Transforming Growth Factor beta | 2011 |
Gadolinium deposition in nephrogenic fibrosing dermopathy.
Topics: Acidosis; Aged; Blood Vessels; Bone Marrow Cells; Calcium Phosphates; Contrast Media; Cyclosporine; Electron Probe Microanalysis; Female; Fibrosis; Gadolinium; Hepatitis C, Chronic; Humans; Hypocalcemia; Kidney Failure, Chronic; Liver Failure; Magnetic Resonance Imaging; Microscopy, Electron, Scanning; Models, Biological; Phosphates; Postoperative Complications; Renal Dialysis; Skin; Skin Diseases | 2007 |
Activation of dermal connective tissue in scleroderma.
Topics: Cell Adhesion Molecules; Chemotaxis, Leukocyte; Collagen; Connective Tissue; Cyclosporine; Cytokines; Female; Fibroblasts; Fibrosis; Humans; Integrins; Interferon-gamma; Male; Penicillamine; Photopheresis; Platelet-Derived Growth Factor; Procollagen-Proline Dioxygenase; Scleroderma, Systemic; Sex Ratio; Transcription, Genetic; Transforming Growth Factor beta | 1993 |
25 trial(s) available for cyclosporine and Cirrhosis
| Article | Year |
|---|---|
Steroid resistant focal segmental glomerulosclerosis: effect of arterial hyalinosis on outcome: single center study.
Topics: Adult; Arterioles; Blood Pressure; Cyclosporine; Diarrhea; Drug Resistance; Drug Therapy, Combination; Eye Diseases, Hereditary; Female; Fibrosis; Glomerular Filtration Rate; Glomerulosclerosis, Focal Segmental; Glucocorticoids; Humans; Hyalin; Immunosuppressive Agents; Intestinal Diseases; Male; Mycophenolic Acid; Prednisolone; Prospective Studies; Proteinuria; Skin Abnormalities; Treatment Outcome; Vascular Diseases | 2021 |
Progression of pulse pressure in kidney recipients durably exposed to CsA is a risk factor for epithelial phenotypic changes: an ancillary study of the CONCEPT trial.
Topics: Adult; Blood Pressure; Calcineurin Inhibitors; Cyclosporine; Epithelium; Female; Fibrosis; Glomerular Filtration Rate; Graft Rejection; Humans; Immunosuppressive Agents; Kidney; Kidney Transplantation; Male; Middle Aged; Phenotype; Risk Factors; Sirolimus; Time Factors | 2014 |
Transcriptional profiling of belatacept and calcineurin inhibitor therapy in renal allograft recipients.
Topics: Abatacept; Adult; Allografts; Biomarkers; Biopsy; Calcineurin Inhibitors; Cell Differentiation; CTLA-4 Antigen; Cyclosporine; Female; Fibrosis; Gene Expression Profiling; Gene Expression Regulation; Humans; Immunoconjugates; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Prospective Studies; Randomized Controlled Trials as Topic; Transcription, Genetic; Young Adult | 2014 |
Renal function three years after early conversion from a calcineurin inhibitor to everolimus: results from a randomized trial in kidney transplantation.
Topics: Adult; Aged; Biopsy; Calcineurin Inhibitors; Cyclosporine; Everolimus; Female; Fibrosis; Glomerular Filtration Rate; Graft Rejection; Graft Survival; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Kidney; Kidney Transplantation; Male; Middle Aged; Renal Insufficiency; Sirolimus; Treatment Outcome | 2015 |
Side effects of the calcineurin inhibitor, such as new-onset diabetes after kidney transplantation.
Topics: Adult; Age Factors; Aged; Atrophy; Biopsy; Blood Glucose; Calcineurin; Calcineurin Inhibitors; Cyclosporine; Diabetes Mellitus; Fasting; Female; Fibrosis; Glucose Tolerance Test; Graft Rejection; Humans; Hungary; Immunosuppressive Agents; Incidence; Kidney; Kidney Transplantation; Male; Middle Aged; Risk Factors; Tacrolimus; Time Factors | 2014 |
Fibrosis progression according to epithelial-mesenchymal transition profile: a randomized trial of everolimus versus CsA.
Topics: Adolescent; Adult; Aged; Biopsy; Calcineurin Inhibitors; Cyclosporine; Disease Progression; Epithelial-Mesenchymal Transition; Everolimus; Female; Fibrosis; Graft Survival; Humans; Immunosuppression Therapy; Inflammation; Kidney; Kidney Transplantation; Male; Middle Aged; Prospective Studies; Renal Insufficiency; Risk Factors; Treatment Outcome | 2015 |
Minimization of maintenance immunosuppression early after renal transplantation: an interim analysis.
Topics: Adult; Aged; Biomarkers; Biopsy; Creatinine; Cyclosporine; Drug Administration Schedule; Drug Monitoring; Drug Therapy, Combination; Everolimus; Female; Fibrosis; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Mycophenolic Acid; Netherlands; Prednisolone; Prospective Studies; Sirolimus; Time Factors; Treatment Outcome | 2009 |
Interstitial fibrosis quantification in renal transplant recipients randomized to continue cyclosporine or convert to sirolimus.
Topics: Adult; Biopsy; Chronic Disease; Cyclosporine; Female; Fibrosis; Glomerular Filtration Rate; Graft Rejection; Humans; Immunosuppressive Agents; Kidney; Kidney Transplantation; Male; Middle Aged; Sirolimus; Transplantation, Homologous; Treatment Outcome | 2009 |
Primary immunosuppression with tacrolimus is associated with a reduction in renal allograft fibrosis compared with neoral therapy.
Topics: Cyclosporine; Drug Therapy, Combination; Fibrosis; Follow-Up Studies; Graft Survival; Humans; Immunosuppressive Agents; Kidney Function Tests; Kidney Transplantation; Tacrolimus; Time Factors | 2002 |
Long-term renal effects of low-dose cyclosporine in uveitis-treated patients: follow-up study.
Topics: Adult; Atrophy; Cohort Studies; Creatinine; Cyclosporine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fibrosis; Follow-Up Studies; Glomerular Filtration Rate; Humans; Hypertension; Immunosuppressive Agents; Kidney; Kidney Tubules; Male; Middle Aged; Prospective Studies; Uveitis | 2002 |
Randomized clinical trial of the effect of microemulsion cyclosporin and tacrolimus on renal allograft fibrosis.
Topics: Adult; Analysis of Variance; Aspirin; Cyclosporine; Extracellular Matrix; Female; Fibrosis; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Nifedipine; Prednisolone; Prospective Studies; Tacrolimus; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination | 2003 |
Fibrosis-associated gene expression in renal transplant glomeruli after acute renal allograft rejection.
Topics: Acute Disease; Adolescent; Adult; Cyclosporine; Female; Fibrosis; Gene Expression; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Glomerulus; Kidney Transplantation; Male; Middle Aged; RNA, Messenger; Tacrolimus; Transforming Growth Factors; Transplantation, Homologous | 2003 |
Cyclosporine in patients with steroid-resistant nephrotic syndrome: an open-label, nonrandomized, retrospective study.
Topics: Adolescent; Adult; Child; Child, Preschool; Cyclosporine; Drug Administration Schedule; Drug Resistance; Female; Fibrosis; Humans; Immunosuppressive Agents; Kidney; Male; Nephrotic Syndrome; Retrospective Studies; Steroids; Time Factors; Treatment Outcome | 2004 |
Impact of mycophenolate mofetil versus azathioprine on early recurrence of hepatitis C after liver transplantation.
Topics: Adult; Azathioprine; Cyclosporine; Female; Fibrosis; Graft Rejection; Hepatitis C; Humans; Immunosuppressive Agents; Incidence; Liver Transplantation; Male; Middle Aged; Mycophenolic Acid; Prospective Studies; Recurrence; Severity of Illness Index | 2005 |
No difference in degree of interstitial Sirius red-stained area in serial biopsies from area under concentration-over-time curves-guided cyclosporine versus tacrolimus-treated renal transplant recipients at one year.
Topics: Area Under Curve; Azo Compounds; Biopsy; Calcineurin Inhibitors; Cyclosporine; Fibrosis; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Kidney; Kidney Transplantation; Prospective Studies; Staining and Labeling; Tacrolimus | 2006 |
Molecular comparison of calcineurin inhibitor-induced fibrogenic responses in protocol renal transplant biopsies.
Topics: Adult; Biomarkers; Biopsy, Needle; Collagen; Cyclosporine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fibrosis; Follow-Up Studies; Graft Rejection; Graft Survival; Humans; Immunohistochemistry; Kidney Transplantation; Male; Middle Aged; Probability; Reference Values; Risk Assessment; RNA, Messenger; Tacrolimus; Transforming Growth Factor beta; Transplantation, Homologous; Treatment Outcome | 2006 |
Untreated rejection in 6-month protocol biopsies is not associated with fibrosis in serial biopsies or with loss of graft function.
Topics: Adult; Area Under Curve; Biopsy; Calcineurin Inhibitors; Cyclosporine; Diabetes Mellitus, Type 2; Female; Fibrosis; Graft Rejection; Graft Survival; Humans; Kidney; Kidney Transplantation; Male; Middle Aged; Tacrolimus | 2006 |
Quantification of interstitial fibrosis by image analysis on routine renal biopsy 1 year after transplantation in patients managed by C2 monitoring of cyclosporine microemulsion.
Topics: Adult; Biopsy; Cyclosporine; Emulsions; Female; Fibrosis; Follow-Up Studies; Histocompatibility Testing; Humans; Image Processing, Computer-Assisted; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Monitoring, Physiologic | 2007 |
The histopathological changes associated with allograft rejection and drug toxicity in renal transplant recipients maintained on FK506. Clinical significance and comparison with cyclosporine.
Topics: Adult; Biopsy, Needle; Cyclosporine; Female; Fibrosis; Glomerulosclerosis, Focal Segmental; Graft Rejection; Humans; Immunosuppression Therapy; Kidney; Kidney Transplantation; Male; Middle Aged; Prospective Studies; Signal Transduction; Tacrolimus; Time Factors; Transplantation, Homologous | 1993 |
A prospective study of renal structure and function in psoriasis patients treated with cyclosporin.
Topics: Adult; Aged; Creatinine; Cyclosporine; Female; Fibrosis; Glomerular Filtration Rate; Humans; Iothalamic Acid; Kidney; Male; Middle Aged; Prospective Studies; Psoriasis; Time Factors | 1994 |
Influence of nifedipine on interstitial fibrosis in renal transplant allografts treated with cyclosporin A.
Topics: Azathioprine; Cyclosporine; Fibrosis; Glomerular Filtration Rate; Humans; Immunosuppression Therapy; Kidney; Kidney Transplantation; Nifedipine; Single-Blind Method; Time Factors | 1994 |
Quantitative morphometry of renal biopsies prior to cyclosporine in nephrotic syndrome.
Topics: Adolescent; Anti-Inflammatory Agents; Child; Child, Preschool; Cyclosporine; Drug Resistance; Female; Fibrosis; Glomerulonephritis, Membranoproliferative; Glomerulosclerosis, Focal Segmental; Humans; Immunoglobulin M; Immunosuppressive Agents; Infant; Kidney; Kidney Function Tests; Male; Nephrotic Syndrome; Steroids | 1998 |
Effect of acute rejection on expression of fibrosis associated genes in renal transplant recipients.
Topics: Acute Disease; Adult; Collagen; Cyclosporine; Female; Fibrosis; Gene Expression Regulation; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Glomerulus; Kidney Transplantation; Male; Matrix Metalloproteinase 2; Reverse Transcriptase Polymerase Chain Reaction; Tacrolimus; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Transcription, Genetic; Transforming Growth Factor beta | 2000 |
Differential effects of cyclosporin and tacrolimus on the expression of fibrosis-associated genes in isolated glomeruli from renal transplants.
Topics: Adult; Collagen; Cyclosporine; Female; Fibrosis; Gene Expression; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Glomerulus; Kidney Transplantation; Male; Matrix Metalloproteinase 2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tacrolimus; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Transforming Growth Factor beta | 2000 |
Molecular and structural consequences of early renal allograft injury.
Topics: Adult; Cyclosporine; Female; Fibronectins; Fibrosis; Gene Expression; Graft Rejection; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Prospective Studies; RNA, Messenger; Tacrolimus; Thrombospondins; Transforming Growth Factor beta; Transforming Growth Factor beta1; Transplantation, Homologous | 2002 |
178 other study(ies) available for cyclosporine and Cirrhosis
| Article | Year |
|---|---|
Nanoformulation of a carbon monoxide releasing molecule protects against cyclosporin A-induced nephrotoxicity and renal fibrosis via the suppression of the NLRP3 inflammasome mediated TGF-β/Smad pathway.
Topics: Animals; Anti-Inflammatory Agents; Carbon Monoxide; Cyclosporine; Fibrosis; Humans; Inflammasomes; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; Transforming Growth Factor beta | 2022 |
Nontoxic Concentration of Ochratoxin A Aggravates Renal Fibrosis Induced by Adriamycin/Cyclosporine A Nephropathy via TGF-β1/SMAD2/3.
Topics: Animals; Cyclosporine; Doxorubicin; Fibrosis; Mice; Renal Insufficiency, Chronic; Transforming Growth Factor beta1 | 2022 |
Cyclosporine A induces cardiac remodeling through TGF-β/Smad3/miR-29 signaling pathway and alters gene expression of miR-30b-5p/CaMKIIδ isoforms pathways: alleviating effects of moderate exercise.
Topics: Animals; Cyclosporine; Fibrosis; Gene Expression; Male; MicroRNAs; Protein Isoforms; Rats; Rats, Wistar; Signal Transduction; Transforming Growth Factor beta; Ventricular Remodeling | 2023 |
Preclinical Study of DNA-Recognized Peptide Compound Pyrrole-Imidazole Polyamide Targeting Human TGF-β1 Promoter for Progressive Renal Diseases in the Common Marmoset.
Topics: Animals; Base Sequence; Cadherins; Callithrix; Cyclosporine; DNA; Fibrosis; Humans; Imidazoles; Kidney; Kidney Diseases; Nylons; Peptides; Promoter Regions, Genetic; Pyrroles; RNA, Messenger; Snail Family Transcription Factors; Transforming Growth Factor beta1; Urethral Obstruction | 2019 |
PPAR γ/TLR4/TGF-β1 axis mediates the protection effect of erythropoietin on cyclosporin A-induced chronic nephropathy in rat.
Topics: Animals; Cyclosporine; Cytokines; Erythropoietin; Fibrosis; Inflammation; Kidney; Male; PPAR gamma; Rats; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; Toll-Like Receptor 4; Transforming Growth Factor beta1 | 2020 |
The Secretome Analysis of Activated Human Renal Fibroblasts Revealed Beneficial Effect of the Modulation of the Secreted Peptidyl-Prolyl Cis-Trans Isomerase A in Kidney Fibrosis.
Topics: Cell Line, Transformed; Cell Survival; Cyclosporine; Disease Progression; Down-Regulation; Extracellular Matrix; Fibroblasts; Fibronectins; Fibrosis; Humans; Inflammation; Kidney; Peptidylprolyl Isomerase; Phenotype; Proteome; RNA, Small Interfering; Tacrolimus | 2020 |
Proteomic Characterization of Urinary Extracellular Vesicles from Kidney-Transplanted Patients Treated with Calcineurin Inhibitors.
Topics: Adult; Aged; Biomarkers; Calcineurin Inhibitors; Cyclosporine; Extracellular Vesicles; Female; Fibrosis; Graft Survival; Humans; Kidney; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Plakins; Proteome; Tacrolimus; Uroplakins | 2020 |
Calcineurin A-α suppression drives nuclear factor-κB-mediated NADPH oxidase-2 upregulation.
Topics: Animals; Calcineurin; Calcineurin Inhibitors; Cell Line; Cyclosporine; Fibrosis; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidase 2; NF-kappa B; Oxidative Stress; Reactive Oxygen Species; Up-Regulation | 2021 |
Sodium-glucose cotransporter 2 inhibition prevents renal fibrosis in cyclosporine nephropathy.
Topics: Animals; Benzhydryl Compounds; Blood Pressure; Cyclosporine; Fibrosis; Glucosides; Kidney; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2021 |
Lysyl oxidase inhibitors attenuate cyclosporin A-induced nephropathy in mouse.
Topics: Amino Acid Oxidoreductases; Animals; Cyclosporine; Disease Models, Animal; Extracellular Matrix; Extracellular Matrix Proteins; Fibrosis; Humans; Kidney Diseases; Kidney Tubules; Male; Mice; Protective Agents; Protein-Lysine 6-Oxidase | 2021 |
Nephrotoxicity in children with frequently relapsing nephrotic syndrome receiving long-term cyclosporine treatment.
Topics: Adolescent; Biopsy; Child; Child, Preschool; Cyclosporine; Female; Fibrosis; Glucocorticoids; Humans; Kidney; Long-Term Care; Maintenance Chemotherapy; Male; Nephrotic Syndrome; Prednisolone; Retrospective Studies | 2017 |
Effects of the Vitamin D Analog 2AMD in Cyclosporine-Induced Nephrotoxicity: Dose-Response and Antifibrotic Activity.
Topics: Animals; Blood Urea Nitrogen; Calcitriol; Calcium; Collagen; Cyclosporine; Disease Models, Animal; Dose-Response Relationship, Drug; Fibronectins; Fibrosis; Immunosuppressive Agents; Kidney; Male; Rats, Sprague-Dawley; Renal Agents; Renal Insufficiency, Chronic; Vimentin | 2017 |
D‑Pinitol alleviates cyclosporine A‑induced renal tubulointerstitial fibrosis via activating Sirt1 and Nrf2 antioxidant pathways.
Topics: Animals; Antioxidants; Cyclosporine; Fibrosis; Inositol; Kidney; Kidney Diseases; Kidney Function Tests; Male; Mice, Inbred ICR; NF-E2-Related Factor 2; Oxidative Stress; Sirtuin 1 | 2018 |
Cyclosporin A induces autophagy in cardiac fibroblasts through the NRP-2/WDFY-1 axis.
Topics: Adaptor Proteins, Signal Transducing; Animals; Autophagy; Cell Proliferation; Collagen Type I; Cyclosporine; Cytokines; Down-Regulation; Fibroblasts; Fibrosis; Myocardium; Neuropilin-2; Phenotype; Rats; Rats, Wistar; Up-Regulation | 2018 |
Molecular basis of the counteraction by calcium channel blockers of cyclosporine nephrotoxicity.
Topics: Animals; Biomarkers; Blood Urea Nitrogen; Calcium Channel Blockers; Collagen Type IV; Creatinine; Cyclosporine; Dual Oxidases; Fibrosis; Inflammation Mediators; Kidney; Kidney Diseases; Male; NADPH Oxidases; NF-kappa B; Nifedipine; Oxidative Stress; Proteinuria; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Transforming Growth Factor beta1; Verapamil | 2018 |
Vitamin E inhibits cyclosporin A-induced CTGF and TIMP-1 expression by repressing ROS-mediated activation of TGF-β/Smad signaling pathway in rat liver.
Topics: Animals; Antibodies, Neutralizing; Cells, Cultured; Connective Tissue Growth Factor; Cyclosporine; Drug Synergism; Drug Therapy, Combination; Fibrosis; Lipid Peroxidation; Liver; Male; Oxidative Stress; Phosphorylation; Rats; Rats, Wistar; Reactive Oxygen Species; Signal Transduction; Smad Proteins; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta; Up-Regulation; Vitamin E | 2018 |
5-aminolaevulinic acid (ALA), enhances heme oxygenase (HO)-1 expression and attenuates tubulointerstitial fibrosis and renal apoptosis in chronic cyclosporine nephropathy.
Topics: Aminolevulinic Acid; Animals; Apoptosis; Atrophy; Cyclosporine; Cytokines; Drug Therapy, Combination; Fibrosis; Heme Oxygenase-1; Inflammation; Iron; Levulinic Acids; Mice; Nephritis, Interstitial; Oxidative Stress; RNA, Messenger | 2019 |
Tauroursodeoxycholic acid attenuates cyclosporine-induced renal fibrogenesis in the mouse model.
Topics: Animals; Cyclosporine; Disease Models, Animal; Fibrosis; Kidney; Kidney Diseases; Male; Mice; Taurochenodeoxycholic Acid; Unfolded Protein Response | 2019 |
Metformin Attenuates Cyclosporine A-induced Renal Fibrosis in Rats.
Topics: Animals; Creatinine; Cyclosporine; Disease Models, Animal; Fibrosis; Humans; Immunosuppressive Agents; Kidney; Male; MAP Kinase Signaling System; Metformin; Oxidative Stress; Phosphorylation; Rats; Rats, Sprague-Dawley; Renal Elimination | 2019 |
The Protective Effect of Fluorofenidone against Cyclosporine A-Induced Nephrotoxicity.
Topics: Animals; Apoptosis; Cyclosporine; Dose-Response Relationship, Drug; Fibrosis; Kidney; Male; Protective Agents; Pyridones; Rats; Rats, Sprague-Dawley | 2019 |
The mineralocorticoid receptor antagonist eplerenone reduces renal interstitial fibrosis after long-term cyclosporine treatment in rat: antagonizing cyclosporine nephrotoxicity.
Topics: Animals; Cyclosporine; Drug Interactions; Eplerenone; Fibrosis; Immunosuppressive Agents; Kidney; Longitudinal Studies; Male; Mineralocorticoid Receptor Antagonists; Nephritis, Interstitial; Rats; Rats, Sprague-Dawley; Spironolactone; Treatment Outcome | 2013 |
Human adipose tissue derived mesenchymal stem cells aggravate chronic cyclosporin nephrotoxicity by the induction of oxidative stress.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adipose Tissue; Animals; Apoptosis; Cell Line; Culture Media, Conditioned; Cyclosporine; Deoxyguanosine; Fibrosis; Humans; Kidney; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Oxidative Stress; Rats; Rats, Sprague-Dawley; Time Factors | 2013 |
Protective effects of HBSP on ischemia reperfusion and cyclosporine a induced renal injury.
Topics: Acute Kidney Injury; Animals; Apoptosis; Caspase 3; Cyclosporine; Enzyme Activation; Erythropoietin; Fibrosis; Gene Expression; Inflammation; Kidney; Kidney Function Tests; Male; Peptide Fragments; Protective Agents; Rats; Reperfusion Injury; RNA, Messenger | 2013 |
Celecoxib offsets the negative renal influences of cyclosporine via modulation of the TGF-β1/IL-2/COX-2/endothelin ET(B) receptor cascade.
Topics: Animals; Celecoxib; Creatinine; Cyclooxygenase 2; Cyclosporine; Fibrosis; Immunosuppressive Agents; Interleukin-2; Kidney; Kidney Diseases; Male; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Signal Transduction; Sulfonamides; Transforming Growth Factor beta1 | 2014 |
Delayed treatment with oleanolic acid attenuates tubulointerstitial fibrosis in chronic cyclosporine nephropathy through Nrf2/HO-1 signaling.
Topics: Adaptor Proteins, Signal Transducing; Animals; Antioxidants; Apoptosis; Biomarkers; Cell Nucleus; Cyclosporine; Cytoskeletal Proteins; Fibrosis; Heme Oxygenase-1; Kelch-Like ECH-Associated Protein 1; Kidney Diseases; Kidney Function Tests; Kidney Tubules; Male; Malondialdehyde; Mice; Mice, Inbred ICR; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Oleanolic Acid; Proto-Oncogene Proteins c-bcl-2; Signal Transduction | 2014 |
Different effects of tacrolimus and cyclosporine on PDGF induction and chronic allograft injury: evidence for improved kidney graft outcome.
Topics: Animals; Cells, Cultured; Chronic Disease; Cyclosporine; Fibrosis; Gene Expression Regulation; Graft Rejection; Immunosuppression Therapy; Kidney; Kidney Transplantation; Macrophages; Male; Platelet-Derived Growth Factor; Rats; Rats, Inbred WF; Tacrolimus; Transplantation, Homologous | 2014 |
Cyclosporine-mediated allograft fibrosis is associated with micro-RNA-21 through AKT signaling.
Topics: Allografts; Animals; Calcineurin Inhibitors; Cells, Cultured; Cyclosporine; Epithelial-Mesenchymal Transition; Extracellular Signal-Regulated MAP Kinases; Fibrosis; Humans; Kidney; Mice; MicroRNAs; Phosphorylation; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Signal Transduction; Smad7 Protein; Transforming Growth Factor beta | 2015 |
Inhibition of local aldosterone by eplerenone reduces renal structural damage in a novel model of chronic cyclosporine A nephrotoxicity.
Topics: Adrenalectomy; Aldosterone; Animals; Chronic Disease; Cyclosporine; Cytochrome P-450 CYP11B2; Disease Models, Animal; Electrolytes; Eplerenone; Fibrosis; Kidney; Kidney Diseases; Male; Potassium; Rats, Sprague-Dawley; RNA, Messenger; Sodium; Spironolactone | 2015 |
Celecoxib, but not indomethacin, ameliorates the hypertensive and perivascular fibrotic actions of cyclosporine in rats: role of endothelin signaling.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Celecoxib; Cyclosporine; Cytoprotection; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelins; Fibrosis; Heart Rate; Hypertension; Indomethacin; Male; Pyrazoles; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Renal Artery; Signal Transduction; Sulfonamides; Vascular Remodeling | 2015 |
Calcineurin-inhibition Results in Upregulation of Local Renin and Subsequent Vascular Endothelial Growth Factor Production in Renal Collecting Ducts.
Topics: Amides; Animals; Biomarkers; Calcineurin Inhibitors; Capillaries; Collagen Type I; Creatinine; Cyclosporine; Cytoprotection; Disease Models, Animal; Fibrosis; Flow Cytometry; Fumarates; Immunosuppressive Agents; Kidney Diseases; Kidney Tubules, Collecting; Male; Mice, Inbred C57BL; Microscopy, Fluorescence, Multiphoton; Real-Time Polymerase Chain Reaction; Renal Circulation; Renin; Renin-Angiotensin System; Tacrolimus; Time Factors; Up-Regulation; Vascular Endothelial Growth Factor A | 2016 |
The protective effect of neutralizing high-mobility group box1 against chronic cyclosporine nephrotoxicity in mice.
Topics: Animals; Antibodies, Blocking; Calcineurin Inhibitors; Cells, Cultured; Creatinine; Cyclosporine; Fibrosis; Graft Rejection; Graft Survival; HMGB1 Protein; Immunity, Innate; Immunosuppressive Agents; Kidney Transplantation; Kidney Tubules; Male; Mice; Mice, Inbred ICR; Nephritis, Interstitial; NF-kappa B; Toll-Like Receptor 4; Transforming Growth Factor beta | 2016 |
Beneficial effects of nilotinib, tyrosine kinase inhibitor on cyclosporine-A induced renal damage in rats.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Cyclosporine; Fibrosis; Kidney; Kidney Diseases; Male; NF-kappa B; Oxidative Stress; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Superoxide Dismutase | 2016 |
Development of a novel CsA-PLGA drug delivery system based on a glaucoma drainage device for the prevention of postoperative fibrosis.
Topics: Animals; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclosporine; Drainage; Drug Carriers; Drug Liberation; Eye; Fibroblasts; Fibrosis; Fluorescein Angiography; Glaucoma; Immunohistochemistry; Intraocular Pressure; Lactic Acid; Microscopy, Electron, Scanning; Neovascularization, Physiologic; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits; Thermogravimetry | 2016 |
Curcumin attenuates cyclosporine A‑induced renal fibrosis by inhibiting hypermethylation of the klotho promoter.
Topics: Animals; Antifungal Agents; Cell Line; Curcumin; Cyclosporine; DNA Methylation; Female; Fibrosis; Glucuronidase; Humans; Kidney; Klotho Proteins; Mice, Inbred C57BL; Promoter Regions, Genetic; Protective Agents; Renal Insufficiency, Chronic | 2016 |
TLR4-mediated inflammation is a key pathogenic event leading to kidney damage and fibrosis in cyclosporine nephrotoxicity.
Topics: Animals; Cyclosporine; Cytokines; Fibrosis; HMGB1 Protein; Immunosuppressive Agents; Inflammation; Kidney; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Rats; Sulfonamides; Toll-Like Receptor 4 | 2017 |
TAFRO syndrome with primary Sjogren's syndrome.
Topics: Adult; Bacterial Infections; Bone Marrow; Cyclosporine; Edema; Female; Fever; Fibrosis; Humans; Lymph Nodes; Lymphadenitis; POEMS Syndrome; Reticulin; Sjogren's Syndrome; Syndrome; Thrombocytopenia; Treatment Outcome | 2016 |
4PBA strongly attenuates endoplasmic reticulum stress, fibrosis, and mitochondrial apoptosis markers in cyclosporine treated human gingival fibroblasts.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Cell Survival; Cells, Cultured; Cyclosporine; Cytoprotection; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Fibroblasts; Fibrosis; Gingiva; Gingival Overgrowth; Humans; Melatonin; Mitochondria; Phenylbutyrates; Signal Transduction; Simvastatin | 2018 |
Fibroblast dynamics as an in vitro screening platform for anti-fibrotic drugs in primary myelofibrosis.
Topics: Cell Line; Cell Proliferation; Collagen; Cyclosporine; Dose-Response Relationship, Drug; Drug Discovery; Fibroblasts; Fibrosis; Gene Expression Regulation; High-Throughput Screening Assays; Janus Kinase 2; Kinetics; Mutation; Mycophenolic Acid; Primary Myelofibrosis; Transforming Growth Factor beta | 2018 |
Molecular mechanisms of TGF beta receptor-triggered signaling cascades rapidly induced by the calcineurin inhibitors cyclosporin A and FK506.
Topics: Animals; Calcineurin Inhibitors; Cells, Cultured; Cyclosporine; Fibrosis; Humans; Injections, Intraperitoneal; Male; Mesangial Cells; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Receptor, Transforming Growth Factor-beta Type I; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Signal Transduction; Smad2 Protein; Tacrolimus; Transforming Growth Factor beta1 | 2008 |
NIM811 (N-methyl-4-isoleucine cyclosporine), a mitochondrial permeability transition inhibitor, attenuates cholestatic liver injury but not fibrosis in mice.
Topics: Animals; Cell Death; Cholestasis; Collagen; Cyclosporine; Fibrosis; Hepatocytes; Membrane Potentials; Mice; Mitochondrial Membranes; Permeability | 2008 |
The experimental study of cardiac allograft vasculopathy and myocardial fibrosis in rats.
Topics: Animals; Cyclosporine; Female; Fibrosis; Graft Rejection; Heart; Heart Transplantation; Immunosuppressive Agents; Male; Myocardium; Rats; Rats, Sprague-Dawley; Rats, Wistar; Transplantation, Homologous | 2008 |
Expression of fibrosis-associated molecules in IgA nephropathy treated with cyclosporine.
Topics: Adolescent; Capillaries; Child; Child, Preschool; Cyclosporine; Female; Fibrosis; Glomerulonephritis, IGA; Humans; Immunohistochemistry; Immunosuppressive Agents; Kidney; Male; Osteopontin; Transforming Growth Factor beta | 2009 |
Effect of cytomegalovirus viremia on subclinical rejection or interstitial fibrosis and tubular atrophy in protocol biopsy at 3 months in renal allograft recipients managed by preemptive therapy or antiviral prophylaxis.
Topics: Adult; Antiviral Agents; Atrophy; Biopsy; Cyclosporine; Cytomegalovirus Infections; Female; Fibrosis; Follow-Up Studies; Humans; Immunosuppressive Agents; Kidney Transplantation; Kidney Tubules; Male; Middle Aged; Patient Selection; Retrospective Studies; Risk Factors; Survival Analysis; Survivors; Time Factors; Viral Load; Viremia | 2009 |
Adverse effects of cyclosporine A on HSP25, alpha B-crystallin and myofibrillar cytoskeleton in rat heart.
Topics: Actinin; Actins; alpha-Crystallin B Chain; Animals; Cyclosporine; Cytoskeleton; Desmin; Fibrosis; HSP27 Heat-Shock Proteins; Immunosuppressive Agents; Male; Microscopy, Electron, Transmission; Myocytes, Cardiac; Protein Transport; Rats; Rats, Sprague-Dawley; Sarcomeres; Time Factors | 2009 |
Protective effects of Mizoribine on Cyclosporine A nephropathy in rats.
Topics: Animals; Anti-Inflammatory Agents; Body Weight; Cyclosporine; Disease Progression; Fibrosis; Immunohistochemistry; Immunosuppressive Agents; Inflammation; Kidney; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Ribonucleosides | 2009 |
Cyclosporine A-induced neck fibrosis in a patient with adult-onset Still's disease.
Topics: Adult; Antirheumatic Agents; Cyclosporine; Fibrosis; Humans; Male; Neck; Still's Disease, Adult-Onset; Treatment Outcome | 2010 |
CD4+ T cells control the differentiation of Gr1+ monocytes into fibrocytes.
Topics: Animals; CD4-Positive T-Lymphocytes; Cell Differentiation; Cells, Cultured; Collagen Type I; Cyclosporine; Cytokines; Female; Fibrosis; Immunosuppressive Agents; Kidney; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, SCID; Monocytes; Rats; Rats, Inbred Lew; Receptors, Chemokine; Sirolimus | 2009 |
Cyclosporin A eye drops inhibit fibrosis and inflammatory cell infiltration in murine type I allergic conjunctivitis without affecting the early-phase reaction.
Topics: Animals; Betamethasone; Capillary Permeability; Cell Migration Inhibition; Collagen; Conjunctivitis, Allergic; Cyclosporine; Cytokines; Disease Models, Animal; Eosinophils; Fibrosis; Immunosuppressive Agents; Male; Mice; Mice, Inbred BALB C; Ophthalmic Solutions; Polymerase Chain Reaction; RNA, Messenger; Th2 Cells | 2009 |
Tranilast attenuates chronic cyclosporine nephrotoxicity in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclosporine; Fibrosis; Immunohistochemistry; Kidney; Macrophages; Male; Models, Molecular; ortho-Aminobenzoates; Rats; Rats, Sprague-Dawley; Weight Gain | 2009 |
[Effects of urokinase on renal interstitial fibrosis and transforming growth factor-beta1 in the kidney of rats with chronic cyclosporine A nephropathy].
Topics: Animals; Cyclosporine; Fibrosis; Kidney; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1; Urokinase-Type Plasminogen Activator | 2009 |
The NRF2-heme oxygenase-1 system modulates cyclosporin A-induced epithelial-mesenchymal transition and renal fibrosis.
Topics: Animals; Cyclosporine; Epithelial Cells; Fibrosis; Heme Oxygenase-1; Isothiocyanates; Kidney; Male; Mesoderm; Mice; Mice, Inbred ICR; NF-E2-Related Factor 2; Rats; Sulfoxides; Thiocyanates | 2010 |
Paricalcitol attenuates cyclosporine-induced kidney injury in rats.
Topics: Animals; Apoptosis; Cyclosporine; Ergocalciferols; Fibrosis; Inflammation; Kidney Diseases; Protective Agents; Rats; Signal Transduction; Treatment Outcome | 2010 |
Upregulation of hyaluronan and its binding receptors in an experimental model of chronic cyclosporine nephropathy.
Topics: Actins; Animals; Chronic Disease; Cyclosporine; Diet, Sodium-Restricted; Disease Models, Animal; Fibrosis; Hyaluronan Receptors; Hyaluronic Acid; Immunohistochemistry; Kidney; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Time Factors; Up-Regulation | 2010 |
The anti-fibrotic effect of mycophenolic acid-induced neutral endopeptidase.
Topics: Administration, Oral; Adult; Aged; Azathioprine; Cyclosporine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fibrosis; Follow-Up Studies; Gene Expression Regulation; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Mycophenolic Acid; Neprilysin; Prospective Studies; Risk Assessment; Tablets, Enteric-Coated; Transplantation Immunology; Treatment Outcome | 2010 |
Cyclosporine inhibits profibrotic effects of interleukin-4 and transforming growth factor β on human intrahepatic fibroblasts cultured in vitro.
Topics: Cells, Cultured; Collagen; Cyclosporine; Fibroblasts; Fibrosis; Humans; In Vitro Techniques; Interleukin-4; Liver; Transforming Growth Factor beta | 2010 |
Reducing peak corneal haze after photorefractive keratectomy in rabbits: prednisolone acetate 1.00% versus cyclosporine A 0.05%.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Cell Count; Cornea; Corneal Opacity; Corneal Stroma; Cyclosporine; Fibrosis; Immunosuppressive Agents; Lasers, Excimer; Microscopy, Confocal; Photorefractive Keratectomy; Postoperative Complications; Prednisolone; Rabbits; Wound Healing | 2011 |
[Inhibitory effect of chailing decoction on renal tubular epithelial phenotype transformation in rats with cyclosporine A-induced nephropathy].
Topics: Actins; Animals; Collagen Type III; Cyclosporine; Drugs, Chinese Herbal; Epithelial Cells; Fibrosis; Kidney Diseases; Kidney Tubules; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1 | 2011 |
Rapamycin prevents interstitial fibrosis in renal allografts through decreasing angiogenesis and inflammation.
Topics: Adult; Antigens, CD34; Biopsy; Cell Proliferation; Cyclosporine; Female; Fibrosis; Graft Survival; Humans; Immunosuppressive Agents; Inflammation; Kidney Transplantation; Lymphocytes; Macrophages; Male; Neovascularization, Pathologic; Sirolimus; Transplantation, Homologous | 2011 |
Y-box binding protein-1 mediates profibrotic effects of calcineurin inhibitors in the kidney.
Topics: Animals; Calcineurin Inhibitors; Cell Line; Cell Line, Transformed; Cells, Cultured; Cyclosporine; Dose-Response Relationship, Drug; Fibrosis; Glomerular Mesangium; HEK293 Cells; Humans; Mesangial Cells; Mice; Rats; Y-Box-Binding Protein 1 | 2011 |
Regression of allograft airway fibrosis: the role of MMP-dependent tissue remodeling in obliterative bronchiolitis after lung transplantation.
Topics: Adult; Airway Remodeling; Animals; Bronchiolitis Obliterans; Cyclosporine; Drug Therapy, Combination; Enzyme Inhibitors; Female; Fibrosis; Humans; Immunosuppressive Agents; Lung; Lung Transplantation; Male; Matrix Metalloproteinase Inhibitors; Matrix Metalloproteinases; Myofibroblasts; Postoperative Complications; Rats; Transplantation, Homologous | 2011 |
Use of uric acid-lowering agents limits experimental cyclosporine nephropathy.
Topics: Allopurinol; Animals; Benzbromarone; Cell Proliferation; Cyclosporine; Enzyme Inhibitors; Fibrosis; Hyperuricemia; Immunohistochemistry; Kidney; Kidney Diseases; Male; Osteopontin; Random Allocation; Rats; Rats, Sprague-Dawley; Uric Acid; Uricosuric Agents; Vascular Endothelial Growth Factor A; Xanthine Oxidase | 2012 |
One dose of cyclosporine A is protective at initiation of folic acid-induced acute kidney injury in mice.
Topics: Acute Kidney Injury; Acute-Phase Proteins; Animals; Blood Urea Nitrogen; Creatinine; Cyclosporine; Cytokine TWEAK; Disease Models, Animal; Fibrosis; Folic Acid; Immunosuppressive Agents; Interleukin-6; Lipocalin-2; Lipocalins; Male; Mice; NF-kappa B; Oncogene Proteins; Tumor Necrosis Factors | 2012 |
Carbamylated erythropoietin ameliorates cyclosporine nephropathy without stimulating erythropoiesis.
Topics: Animals; Apoptosis; Collagen Type I; Cyclosporine; Disease Models, Animal; Dogs; Erythropoiesis; Erythropoietin; Fibrosis; Hemoglobins; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Macrophages; Male; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction; Transforming Growth Factor beta1 | 2012 |
Rapamycin is less fibrogenic than Cyclosporin A as demonstrated in a rat model of chronic allograft nephropathy.
Topics: Animals; Cadherins; Connective Tissue Growth Factor; Creatinine; Cyclosporine; Epithelial-Mesenchymal Transition; Fibrosis; Graft Rejection; Immunosuppressive Agents; Kidney; Kidney Transplantation; Male; Models, Animal; Rats; Rats, Inbred F344; Rats, Inbred Lew; Renal Insufficiency, Chronic; Sirolimus; Transplantation, Homologous | 2013 |
Intraparenchymal injection of bone marrow mesenchymal stem cells reduces kidney fibrosis after ischemia-reperfusion in cyclosporine-immunosuppressed rats.
Topics: Adult; Animals; Bone Marrow Cells; Cyclosporine; Disease Models, Animal; Female; Fibrosis; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Middle Aged; Rats; Rats, Inbred Lew; Reperfusion Injury | 2012 |
Previous exposure to cigarette smoke aggravates experimental cyclosporine-induced nephrotoxicity.
Topics: Actins; Animals; Cyclosporine; Disease Models, Animal; Drug Synergism; Fibrosis; Glomerular Filtration Rate; Hematocrit; Hemodynamics; Humans; Immunosuppressive Agents; Kidney; Male; Nephritis, Interstitial; Rats; Rats, Wistar; Smoking; Tyrosine; Vimentin | 2012 |
Does treatment with corticosteroids and cyclosporine reduce transglutaminase type 2 expression in the renal tissue of patients with membranous nephropathy?
Topics: Adult; Aged; Anti-Inflammatory Agents; Biomarkers; Case-Control Studies; Creatinine; Cyclosporine; Disease Progression; Drug Therapy, Combination; Female; Fibrosis; Follow-Up Studies; Glomerulonephritis, Membranous; GTP-Binding Proteins; Humans; Immunosuppressive Agents; Linear Models; Male; Middle Aged; Prednisolone; Protein Glutamine gamma Glutamyltransferase 2; Statistics, Nonparametric; Transglutaminases; Treatment Outcome | 2012 |
[Protective effects of chailing decoction on cyclosporine A induced chronic renal injury and its mechanisms].
Topics: Animals; Apoptosis; Cell Proliferation; Connective Tissue Growth Factor; Cyclosporine; Drugs, Chinese Herbal; Female; Fibrosis; Kidney; Kidney Diseases; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1 | 2012 |
Alterations induced by cyclosporine A in myocardial fibers and extracellular matrix in rat.
Topics: Animals; Blotting, Western; Cyclosporine; Extracellular Matrix; Fibrosis; Heart; Immunohistochemistry; Immunosuppressive Agents; Injections, Subcutaneous; Male; Matrix Metalloproteinase 1; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myocardium; Rats; Rats, Wistar | 2002 |
Colchicine suppresses osteopontin expression and inflammatory cell infiltration in chronic cyclosporine nephrotoxicity.
Topics: Animals; Colchicine; Cyclosporine; Fibrosis; Gene Expression; Immunosuppressive Agents; Inflammation; Kidney; Macrophages; Male; Osteopontin; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sialoglycoproteins | 2002 |
An in vitro model for post-trabeculectomy: evaluation of drugs differently controlling cell proliferation.
Topics: Animals; Cell Division; Cell Survival; Chromans; Cyclosporine; Drug Evaluation; Fibroblasts; Fibrosis; Fluorouracil; Interferon-alpha; Models, Biological; Postoperative Care; Trabeculectomy | 2002 |
Pirfenidone: A novel anti-fibrotic agent and progressive chronic allograft rejection.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclosporine; Cytokines; Cytotoxicity Tests, Immunologic; Disease Models, Animal; Drug Therapy, Combination; Fibrosis; Graft Rejection; Immunosuppressive Agents; Pyridones; Rats; Rats, Inbred Lew; Staining and Labeling; Trachea | 2002 |
Renal warm ischaemic injury in the rat is potentiated by cyclosporine.
Topics: Animals; Cyclosporine; Fibrosis; Immunosuppressive Agents; Kidney; Male; Models, Animal; Rats; Rats, Sprague-Dawley; Renal Circulation; Reperfusion Injury; Temperature | 2002 |
Synergistic effects of mycophenolate mofetil and losartan in a model of chronic cyclosporine nephropathy.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Arterioles; Blood Pressure; Body Weight; Chronic Disease; Cyclosporine; Drug Synergism; Fibrosis; Gene Expression; Immunosuppressive Agents; Kidney; Kidney Diseases; Losartan; Macrophages; Male; Mycophenolic Acid; Osteopontin; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sialoglycoproteins; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2003 |
Apoptosis and expression of BCL-2 and BAX in cyclosporine-induced experimental renal fibrosis.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cyclosporine; Disease Models, Animal; Fibrosis; Immunosuppressive Agents; Kidney; Male; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley | 2003 |
Cyclosporine a slows the progressive renal disease of alport syndrome (X-linked hereditary nephritis): results from a canine model.
Topics: Animals; Body Weight; Creatinine; Cyclosporine; Disease Models, Animal; Disease Progression; Dogs; Fibrosis; Immunosuppressive Agents; Kidney Concentrating Ability; Kidney Glomerulus; Male; Nephritis, Hereditary; Proteinuria | 2003 |
Dystrophic phenotype of canine X-linked muscular dystrophy is mitigated by adenovirus-mediated utrophin gene transfer.
Topics: Adenoviridae; Animals; CD4 Lymphocyte Count; Cyclosporine; Cytoskeletal Proteins; Dog Diseases; Dogs; Dystrophin; Female; Fibrosis; Gene Expression; Genetic Therapy; Genetic Vectors; Immunohistochemistry; Immunosuppressive Agents; Male; Membrane Proteins; Models, Animal; Muscle, Skeletal; Muscular Dystrophy, Animal; Muscular Dystrophy, Duchenne; Transduction, Genetic; Transgenes; Utrophin | 2003 |
Chronic cholestasis and cardiac mitochondrial function in Wistar rats: a model for cardiovascular alterations in chronic liver disease?
Topics: 1-Naphthylisothiocyanate; Animals; Calcium; Cardiovascular Diseases; Cholestasis; Chronic Disease; Cyclosporine; Disease Models, Animal; Female; Fibrosis; Liver Diseases; Mitochondria, Heart; Oxidative Stress; Rats; Rats, Wistar | 2003 |
The effect of combined rapamycin/cyclosporine on the changes in pro-fibrotic gene expression that occur during the development of allograft vasculopathy in rats, compared with cyclosporine or rapamycin in isolation.
Topics: Animals; Aorta; Aortic Diseases; Azo Compounds; Cyclosporine; Drug Therapy, Combination; Fibrosis; Gene Expression; Graft Rejection; Immunosuppressive Agents; Matrix Metalloproteinase 9; Rats; Rats, Inbred F344; Rats, Inbred Lew; Reverse Transcriptase Polymerase Chain Reaction; Sirolimus; Transforming Growth Factor beta; Transplantation, Homologous | 2003 |
Chronic rejection with or without transplant vasculopathy.
Topics: Acute Disease; Adult; Atrophy; Chronic Disease; Cohort Studies; Cyclosporine; Fibrosis; Graft Rejection; Graft Survival; Humans; Kidney Transplantation; Kidney Tubules; Logistic Models; Risk Factors; Time Factors; Vascular Diseases | 2003 |
Early interstitial accumulation of collagen type I discriminates chronic rejection from chronic cyclosporine nephrotoxicity.
Topics: Actins; Adult; Biopsy; Chronic Disease; Collagen Type I; Cyclosporine; Extracellular Matrix; Fibrosis; Graft Rejection; Humans; Image Processing, Computer-Assisted; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Laminin; Middle Aged; Muscle, Smooth; ROC Curve; Time Factors | 2003 |
Pravastatin treatment attenuates interstitial inflammation and fibrosis in a rat model of chronic cyclosporine-induced nephropathy.
Topics: Animals; Anticholesteremic Agents; C-Reactive Protein; Cyclosporine; Fibrosis; Immunosuppressive Agents; Inflammation Mediators; Kidney; Macrophages; Male; Nephritis; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Osteopontin; Pravastatin; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger; Sialoglycoproteins; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2004 |
Differential effects of modern immunosuppressive agents on the development of intimal hyperplasia.
Topics: Angioplasty, Balloon; Animals; Carotid Artery, Common; Collagen Type III; Cyclosporine; Extracellular Matrix Proteins; Fibrosis; Gene Expression; Hyperplasia; Immunosuppressive Agents; Male; Matrix Metalloproteinase Inhibitors; Rats; Rats, Sprague-Dawley; Sirolimus; Tacrolimus; Tissue Inhibitor of Metalloproteinases; Transforming Growth Factor beta; Tunica Intima | 2004 |
Vitamin E attenuates biochemical and morphological features associated with development of chronic pancreatitis.
Topics: Animals; Ceruletide; Chronic Disease; Collagen; Cyclosporine; Fibroblasts; Fibrosis; Lipid Peroxidation; Lipoproteins; Male; Myocytes, Smooth Muscle; Pancreas; Pancreatitis; Rats; Rats, Wistar; Vitamin E | 2004 |
Expression of transforming growth factor-beta-inducible gene-h3 in normal and cyclosporine-treated rat kidney.
Topics: Animals; Cyclosporine; Extracellular Matrix Proteins; Fibrosis; Gene Expression Regulation; Immunosuppressive Agents; In Situ Hybridization; Kidney; Male; Nephritis, Interstitial; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription, Genetic; Transforming Growth Factor beta | 2004 |
Cyclosporine A sensitizes the kidney to tubulointerstitial fibrosis induced by renal warm ischemia.
Topics: Animals; Collagen Type III; Cyclosporine; Fibrosis; Hot Temperature; Immunosuppressive Agents; Ischemia; Kidney; Kidney Transplantation; Male; Matrix Metalloproteinase 2; Nephritis, Interstitial; Rats; Rats, Sprague-Dawley; RNA, Messenger; Severity of Illness Index; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2004 |
Cyclosporin induces renal proto-oncogene RNA message and increased transforming growth factor-beta prior to renal fibrosis: Modification by calcium channel blockade in the salt replete rat.
Topics: Animals; Cyclosporine; DNA; DNA Fragmentation; Fibrosis; Gene Expression Regulation; Genes, Immediate-Early; Immunosuppressive Agents; Kidney; Male; Proto-Oncogenes; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transforming Growth Factor beta; Verapamil | 2004 |
Suppression of cyclosporine a nephrotoxicity in vivo by transforming growth factor beta receptor-immunoglobulin G chimeric protein.
Topics: Animals; Collagen Type IV; Cyclosporine; Female; Fibrosis; Immunoglobulin Fc Fragments; Immunoglobulin G; Immunosuppressive Agents; Mice; Mice, Inbred ICR; Nephritis, Interstitial; Receptors, Transforming Growth Factor beta; Recombinant Fusion Proteins | 2004 |
Long-term follow-up of pediatric transplant recipients: mycophenolic acid trough levels are not a good indicator for long-term graft function.
Topics: Adolescent; Area Under Curve; Biopsy; Child; Child, Preschool; Creatinine; Cyclosporine; Drug Monitoring; Female; Fibrosis; Follow-Up Studies; Glomerular Filtration Rate; Glucocorticoids; Graft Survival; Humans; Immunosuppressive Agents; IMP Dehydrogenase; Infant; Kidney Transplantation; Longitudinal Studies; Male; Mycophenolic Acid; Prednisolone; Prodrugs; Treatment Outcome | 2004 |
Cyclooxygenase-2 expression in experimental post-transplant obliterative bronchiolitis.
Topics: Animals; Azathioprine; Bronchi; Bronchiolitis Obliterans; Chondrocytes; Cyclooxygenase 2; Cyclosporine; Disease Models, Animal; Epithelial Cells; Everolimus; Fibroblasts; Fibrosis; Immunohistochemistry; Immunosuppressive Agents; Isoenzymes; Macrophages; Methylprednisolone; Postoperative Period; Prostaglandin-Endoperoxide Synthases; Sirolimus; Swine | 2004 |
Cyclosporine A induces vascular fibrosis and heat shock protein expression in rat.
Topics: alpha-Crystallin B Chain; Animals; Aorta, Thoracic; Collagen; Connective Tissue; Cyclosporine; Fibrosis; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; HSP47 Heat-Shock Proteins; Immunosuppressive Agents; Male; Neoplasm Proteins; Rats; Rats, Wistar; Serpins; Tunica Intima; Tunica Media | 2005 |
The effect of alpha-melanocyte-stimulating hormone on renal tubular cell apoptosis and tubulointerstitial fibrosis in cyclosporine A nephrotoxicity.
Topics: alpha-MSH; Animals; Antigens, Surface; Apoptosis; bcl-2-Associated X Protein; Chronic Disease; Cyclosporine; Fibrosis; Immunosuppressive Agents; In Situ Nick-End Labeling; Kidney Tubules; Male; Nephritis, Interstitial; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta | 2004 |
Change in renal heme oxygenase expression in cyclosporine A-induced injury.
Topics: Animals; Cyclosporine; Endothelin-1; Enzyme Induction; Fibrosis; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Immunohistochemistry; Immunosuppressive Agents; Kidney; Male; Metalloporphyrins; Protoporphyrins; Rats; Rats, Sprague-Dawley | 2005 |
A multidisciplinary evaluation of the effectiveness of cyclosporine a in dystrophic mdx mice.
Topics: Animals; Body Weight; Calcium; Chlorides; Coloring Agents; Creatine Kinase; Cyclosporine; Electrophysiology; Fibrosis; Fura-2; Immunohistochemistry; Immunosuppressive Agents; Ions; Male; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Muscle, Skeletal; Muscles; Muscular Dystrophies; Physical Conditioning, Animal; Spectrophotometry; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Eosinophilic fasciitis successfully treated with cyclosporine.
Topics: Cyclosporine; Eosinophilia; Fasciitis; Female; Fibrosis; Humans; Immunosuppressive Agents; Middle Aged; Muscle, Skeletal; Remission Induction; Treatment Outcome | 2005 |
Combined effects of losartan and pravastatin on interstitial inflammation and fibrosis in chronic cyclosporine-induced nephropathy.
Topics: Animals; C-Reactive Protein; Cyclosporine; Disease Models, Animal; Fibrosis; Inflammation; Kidney; Kidney Diseases; Losartan; Male; Pravastatin; Rats; Rats, Sprague-Dawley | 2005 |
Provinol prevents CsA-induced nephrotoxicity by reducing reactive oxygen species, iNOS, and NF-kB expression.
Topics: Animals; Biomarkers; Cyclosporine; Fibrosis; Flavonoids; Immunohistochemistry; Immunosuppressive Agents; Kidney; Kidney Diseases; Lipid Peroxidation; NF-kappa B; Nitric Oxide Synthase Type II; Phenols; Polyphenols; Rats; Rats, Wistar; Reactive Oxygen Species | 2005 |
Pancreatic fibrosis in rats and its response to antioxidant treatment.
Topics: Animals; Antioxidants; Ceruletide; Chronic Disease; Cyclosporine; Fibrosis; Glutathione Peroxidase; Male; Oxidative Stress; Pancreas; Pancreatitis; Rats; Rats, Wistar | 2005 |
Cyclosporine A induced epithelial-mesenchymal transition in human renal proximal tubular epithelial cells.
Topics: Actins; Base Sequence; Cadherins; Cell Line; Cell Survival; Connective Tissue Growth Factor; Cyclosporine; DNA; Epithelial Cells; Extracellular Matrix; Fibrosis; Humans; Immediate-Early Proteins; Immunosuppressive Agents; Intercellular Signaling Peptides and Proteins; Kidney Tubules, Proximal; Mesoderm; Nephritis, Interstitial; RNA, Messenger; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Cyclosporine A-induced renal fibrosis: a role for epithelial-mesenchymal transition.
Topics: Cell Differentiation; Cells, Cultured; Cyclosporine; Dose-Response Relationship, Drug; Epithelial Cells; Fibroblasts; Fibrosis; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Tubules, Proximal; Mesoderm; Muscle, Smooth; Protein Kinase C; Protein Kinase C-alpha; Transforming Growth Factor beta; Up-Regulation | 2005 |
Ciliary tissue transplantation in the rabbit.
Topics: Animals; Ciliary Body; Cyclosporine; Female; Fibrosis; Graft Survival; Immunosuppressive Agents; Ischemia; Perfusion; Rabbits; Reperfusion; Time Factors; Transplantation, Homologous; Vascular Endothelial Growth Factor A | 2006 |
Prevention of chronic allograft nephropathy with vitamin D.
Topics: Animals; Blotting, Western; Chronic Disease; Cyclosporine; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Extracellular Matrix; Fibrosis; Graft Rejection; Graft Survival; Immunohistochemistry; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Matrix Metalloproteinases; Rats; Rats, Inbred F344; Rats, Inbred Lew; Rats, Sprague-Dawley; Signal Transduction; Smad7 Protein; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1; Transplantation, Homologous; Vitamin D | 2005 |
Inflammation and caspase activation in long-term renal ischemia/reperfusion injury and immunosuppression in rats.
Topics: Animals; Apoptosis; Caspase 1; Caspase 3; Caspases; Chronic Disease; Cyclosporine; Electrophoresis, Polyacrylamide Gel; Extracellular Matrix; Fibrosis; Glomerulonephritis; Immunosuppressive Agents; Interleukin-1; Male; Mycophenolic Acid; Rats; Rats, Wistar; Reperfusion Injury; Sirolimus; Tacrolimus | 2005 |
The first one thousand liver transplants in Turin: a single-center experience in Italy.
Topics: Adolescent; Adult; Aged; Carcinoma, Hepatocellular; Child; Child, Preschool; Cyclosporine; Fibrosis; Graft Survival; Hepacivirus; Hepatitis B; Hepatitis B virus; Hepatitis C; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Infant; Italy; Liver Neoplasms; Liver Transplantation; Middle Aged; Models, Statistical; Time Factors; Treatment Outcome | 2005 |
Effect of FTY720 on chronic cyclosporine nephropathy in rats.
Topics: Angiotensin II; Animals; Chronic Disease; Cyclosporine; Extracellular Matrix Proteins; Fibrosis; Fingolimod Hydrochloride; Immunosuppressive Agents; Kidney; Kidney Diseases; Lymphocytes; Macrophages; Male; Osteopontin; Propylene Glycols; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sialoglycoproteins; Sphingosine; T-Lymphocytes; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Allogeneic marrow transplantation in patients with severe systemic sclerosis: resolution of dermal fibrosis.
Topics: Adult; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Cyclosporine; Female; Fibrosis; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Methotrexate; Myeloablative Agonists; Scleroderma, Systemic; Skin; Transplantation Conditioning; Transplantation, Homologous | 2006 |
Overexpression of E2A proteins induces epithelial-mesenchymal transition in human renal proximal tubular epithelial cells suggesting a potential role in renal fibrosis.
Topics: Basic Helix-Loop-Helix Transcription Factors; Cell Line; Cyclosporine; Epithelial Cells; Epithelium; Fibroblasts; Fibrosis; Humans; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Tubules, Proximal; TCF Transcription Factors; Transcription Factor 7-Like 1 Protein; Up-Regulation | 2006 |
Mineralocorticoid receptor blockade confers renoprotection in preexisting chronic cyclosporine nephrotoxicity.
Topics: Animals; Apoptosis; Arterioles; Blood Pressure; Body Weight; Caspase 3; Cell Adhesion Molecules; Cyclosporine; Fibrosis; Immunosuppressive Agents; In Situ Nick-End Labeling; Kidney Diseases; Kidney Glomerulus; Kidney Tubules; Male; Membrane Proteins; Mineralocorticoid Receptor Antagonists; Potassium; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA; Spironolactone; Transforming Growth Factor beta | 2007 |
Interference of cyclosporine on glucose metabolism: potential role in chronic transplantation kidney fibrosis.
Topics: Animals; Cell Line; Connective Tissue Growth Factor; Cyclosporine; Fibrosis; Fucose; Gene Expression Regulation; Glucose; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Kidney Transplantation; Kidney Tubules; Postoperative Complications; Rats; Reverse Transcriptase Polymerase Chain Reaction; Smad3 Protein; Smad7 Protein; Transforming Growth Factor beta; Urothelium | 2006 |
Prevention of interstitial fibrosis of renal allograft by angiotensin II blockade.
Topics: Adult; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Cyclosporine; Female; Fibrosis; Humans; Immunosuppressive Agents; Kidney Transplantation; Losartan; Male; Middle Aged; Postoperative Complications | 2006 |
IL-13 is pivotal in the fibro-obliterative process of bronchiolitis obliterans syndrome.
Topics: Animals; Antibodies; Bronchiolitis Obliterans; Bronchoalveolar Lavage Fluid; Cyclosporine; Female; Fibrosis; Graft Rejection; Humans; Interleukin-13; Interleukin-4; Lung Transplantation; Male; Mice; Mice, Mutant Strains; Receptors, Interleukin-13; Syndrome; Transforming Growth Factor beta; Up-Regulation | 2007 |
Mycophenolate mofetil is associated with altered expression of chronic renal transplant histology.
Topics: Adult; Cohort Studies; Cyclosporine; Enzyme Inhibitors; Female; Fibrosis; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Glomerulus; Kidney Transplantation; Kidney Tubules; Male; Mycophenolic Acid; Retrospective Studies; Time Factors | 2007 |
Mitomycin C, 5-fluorouracil, and cyclosporin A prevent epidural fibrosis in an experimental laminectomy model.
Topics: Animals; Antibiotics, Antineoplastic; Cell Count; Cyclosporine; Epidural Space; Fibroblasts; Fibrosis; Fluorouracil; Immunosuppressive Agents; Laminectomy; Lumbar Vertebrae; Male; Mitomycin; Models, Animal; Rats; Rats, Wistar | 2007 |
Protective effects of atorvastatin on chronic allograft nephropathy in rats.
Topics: Animals; Anticholesteremic Agents; Atorvastatin; Chemokines; Chronic Disease; Cyclosporine; Cytokines; Drug Therapy, Combination; Extracellular Matrix Proteins; Fibrosis; Gene Expression; Graft Rejection; Heptanoic Acids; Immunosuppressive Agents; Kidney Transplantation; Male; Monocytes; Proteinuria; Pyrroles; Rats; Rats, Inbred F344; Rats, Inbred Lew; T-Lymphocytes; Transplantation, Homologous | 2007 |
The protective effect of erdosteine against cyclosporine A-induced cardiotoxicity in rats.
Topics: Animals; Catalase; Chemoprevention; Cyclosporine; Disease Models, Animal; Expectorants; Fibrosis; Glutathione Peroxidase; Heart; Heart Diseases; Immunosuppressive Agents; Male; Malondialdehyde; Myocardium; Nitric Oxide; Oxidative Stress; Protein Carbonylation; Rats; Rats, Wistar; Superoxide Dismutase; Thioglycolates; Thiophenes | 2007 |
A rat model reproducing key pathological responses of alcoholic chronic pancreatitis.
Topics: Animals; Cell Death; Ceruletide; Chemokines; Collagen; Cyclosporine; Cytokines; Disease Models, Animal; Ethanol; Fibronectins; Fibrosis; Insulin; Macrophages; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; NF-kappa B; Pancreas; Pancreatitis, Alcoholic; Rats; Rats, Wistar; RNA, Messenger; Severity of Illness Index; Time Factors | 2008 |
Cyclosporin A induces peritoneal fibrosis and angiogenesis during chronic peritoneal exposure to a glucose-based, lactate-buffered dialysis solution in the rat.
Topics: Animals; Cyclosporine; Fibrosis; Glucose; Hemodialysis Solutions; Lactic Acid; Male; Neovascularization, Pathologic; Peritoneal Dialysis; Peritoneal Diseases; Rats; Rats, Wistar | 2007 |
Protein kinase C beta overexpression induces fibrotic effects in human proximal tubular epithelial cells.
Topics: Butadienes; Cell Line; Cell Shape; Cyclosporine; Enzyme Activation; Epithelial Cells; Fibronectins; Fibrosis; Green Fluorescent Proteins; Humans; Imidazoles; Isoenzymes; Kidney Tubules, Proximal; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitriles; Phenotype; Protein Kinase C; Protein Kinase C beta; Pyridines; Pyrones; Recombinant Fusion Proteins; Signal Transduction; Transforming Growth Factor beta1 | 2008 |
Different renal toxicity profiles in the association of cyclosporine and tacrolimus with sirolimus in rats.
Topics: Animals; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcineurin Inhibitors; Cyclosporine; Drug Interactions; Fibrosis; Immunosuppressive Agents; Interferon-gamma; Kidney; Male; Protein Kinases; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sirolimus; Tacrolimus; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2008 |
[Effect of urokinase on renal interstitial inflammation in rats with chronic cyclosporine A nephropathy and its possible mechanism].
Topics: Animals; Chronic Disease; Cyclosporine; Fibrosis; Kidney; Macrophages; Male; Nephritis; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1; Urokinase-Type Plasminogen Activator | 2008 |
Dose-dependent gingival overgrowth induced by cyclosporin in rats.
Topics: Animals; Connective Tissue; Cyclosporine; Dose-Response Relationship, Drug; Epithelium; Fibrosis; Gingival Hyperplasia; Granulation Tissue; Granuloma; Immunosuppressive Agents; Incisor; Intubation, Gastrointestinal; Male; Mandible; Models, Dental; Multivariate Analysis; Periodontal Ligament; Rats; Rats, Sprague-Dawley; Time Factors | 1995 |
Cellular proliferation and macrophage influx precede interstitial fibrosis in cyclosporine nephrotoxicity.
Topics: Animals; Cell Division; Cell Movement; Cyclosporine; Fibrosis; Kidney; Kidney Diseases; Macrophages; Male; Osteopontin; Rats; Rats, Sprague-Dawley; Renin; Sialoglycoproteins | 1995 |
Cyclosporine associated lesions in native kidneys of diabetic pancreas transplant recipients.
Topics: Adolescent; Adult; Arterioles; Atrophy; Biopsy; Cyclosporine; Diabetes Mellitus, Type 1; Female; Fibrosis; Humans; Kidney; Kidney Glomerulus; Male; Pancreas Transplantation; Renal Circulation | 1995 |
Functional effects of myoblast implantation into histoincompatible mice with or without immunosuppression.
Topics: Animals; Cell Count; Cell Transplantation; Cyclosporine; Female; Fibrosis; Graft Rejection; Immunohistochemistry; Immunosuppression Therapy; Mice; Mice, Inbred CBA; Muscle Contraction; Muscle, Skeletal; Regeneration; Time Factors | 1995 |
Combined antagonism of endothelin A/B receptors links endothelin to vasoconstriction whereas angiotensin II effects fibrosis. Studies in chronic cyclosporine nephrotoxicity in rats.
Topics: Angiotensin II; Animals; Cyclosporine; Endothelin Receptor Antagonists; Endothelins; Fibrosis; Kidney Function Tests; Kidney Glomerulus; Male; Rats; Rats, Wistar; Receptor, Endothelin A; Receptor, Endothelin B; Signal Transduction; Vasoconstriction | 1995 |
Renal allograft histology and correlation with function in children on triple therapy.
Topics: Adolescent; Atrophy; Azathioprine; Child; Child, Preschool; Cyclosporine; Drug Therapy, Combination; Female; Fibrosis; Graft Rejection; Humans; Infant; Kidney Function Tests; Kidney Glomerulus; Kidney Transplantation; Kidney Tubules; Male; Methylprednisolone; Prospective Studies; Transplantation, Homologous | 1995 |
Effect of RS61443 on chronic rejection of rat kidney allografts.
Topics: Animals; Cyclosporine; Fibrosis; Graft Rejection; Graft Survival; Immunosuppressive Agents; Kidney Glomerulus; Kidney Transplantation; Kidney Tubules; Male; Mycophenolic Acid; Rats; Rats, Inbred F344; Rats, Inbred Lew; Time Factors; Transplantation, Homologous | 1995 |
Mechanisms of cyclosporine-induced interstitial fibrosis.
Topics: Animals; Creatinine; Cyclosporine; Fibrosis; Kidney; Male; Rats; Rats, Sprague-Dawley; Reference Values | 1994 |
Relevance of Tc-99m DMSA scintigraphy in renal transplant parenchymal imaging.
Topics: Acute Disease; Adult; Azathioprine; Creatinine; Cyclosporine; Edema; Female; Fibrosis; Glucocorticoids; Graft Rejection; Humans; Infarction; Kidney; Kidney Transplantation; Kidney Tubules; Male; Middle Aged; Organotechnetium Compounds; Radionuclide Imaging; Succimer; Technetium Tc 99m Dimercaptosuccinic Acid | 1994 |
Renal function and histomorphology after long-term intravenous administration of cyclosporine for small bowel transplantation in pediatric patients.
Topics: Antibodies, Monoclonal; Antilymphocyte Serum; Biopsy; CD3 Complex; Child; Child, Preschool; Cyclosporine; Fibrosis; Graft Rejection; Humans; Infant; Intestine, Small; Kidney; Kidney Function Tests | 1994 |
International standardization of criteria for histologic diagnosis of chronic rejection in renal allografts.
Topics: Atrophy; Capillaries; Chronic Disease; Cyclosporine; Endarteritis; Fibrosis; Graft Rejection; Humans; International Cooperation; Kidney Transplantation; Kidney Tubules; Nephritis; Observer Variation; Reference Standards; Reproducibility of Results; Transplantation, Homologous | 1994 |
Serum propeptides of type I and III procollagens in renal transplant recipients. A comparison of cyclosporine and azathioprine treatment.
Topics: Adolescent; Adult; Aged; Azathioprine; Collagen; Creatinine; Cyclosporine; Female; Fibrosis; Humans; Kidney; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Peptide Fragments; Procollagen | 1994 |
Cyclosporin A nephropathy: standardization of the evaluation of kidney biopsies.
Topics: Adolescent; Adult; Atrophy; Autoimmune Diseases; Biopsy; Child; Cyclosporine; Female; Fibrosis; Glomerulosclerosis, Focal Segmental; Humans; Kidney; Kidney Diseases; Kidney Glomerulus; Kidney Tubules; Male; Middle Aged; Reproducibility of Results | 1994 |
Morphological and functional renal effects of long-term low-dose cyclosporin A treatment in patients with rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Atrophy; Biopsy; Cyclosporine; Female; Fibrosis; Glomerular Filtration Rate; Humans; Individuality; Kidney; Kidney Tubules; Male; Middle Aged; Time Factors | 1994 |
The kidney in cyclosporin A-treated diabetic patients: a long-term clinicopathological study.
Topics: Adult; Atrophy; Biopsy; Child; Creatinine; Cyclosporine; Diabetes Mellitus, Type 1; Fibrosis; Follow-Up Studies; Humans; Kidney; Kidney Tubules; Risk Factors | 1994 |
Experimental nephrotoxicity, hepatotoxicity and pharmacokinetics of cyclosporin G versus cyclosporin A.
Topics: Acetylglucosaminidase; Animals; Cyclosporine; Cyclosporins; Disease Models, Animal; Fibrosis; Glomerular Filtration Rate; Immunosuppressive Agents; Kidney; Kidney Function Tests; Liver; Liver Function Tests; Male; Rats; Rats, Sprague-Dawley | 1994 |
Evaluation of animal models of chronic vascular rejection.
Topics: Animals; Arteriosclerosis; Atrophy; Chronic Disease; Cyclosporine; Disease Models, Animal; Fibrosis; Graft Rejection; Hyperplasia; Ischemia; Kidney Transplantation; Rats; Rats, Inbred F344; Rats, Inbred Lew; Rats, Inbred Strains; Rats, Wistar; Renal Circulation | 1993 |
Rejection of the component tissues of limb allografts in rats immunosuppressed with FK-506 and cyclosporine.
Topics: Analysis of Variance; Animals; Biopsy; Bone and Bones; Cartilage, Articular; Cyclosporine; Drug Administration Schedule; Epidermis; Fibrosis; Graft Rejection; Hindlimb; Immunosuppression Therapy; Muscle, Skeletal; Necrosis; Pneumonia, Bacterial; Rats; Rats, Inbred ACI; Rats, Inbred Lew; Tacrolimus | 1996 |
Role of transforming growth factor-beta 1 in experimental chronic cyclosporine nephropathy.
Topics: Animals; Body Weight; Chronic Disease; Creatinine; Cyclosporine; Disease Models, Animal; Extracellular Matrix Proteins; Fibrosis; Fluorescent Antibody Technique; Gene Expression; Kidney Cortex; Kidney Diseases; Kidney Medulla; Male; Plasminogen Activator Inhibitor 1; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium; Transforming Growth Factor beta | 1996 |
Topical cyclosporine and glaucoma drainage implant surgery in rabbits.
Topics: Administration, Topical; Animals; Cell Division; Conjunctiva; Cyclosporine; Fibroblasts; Fibrosis; Filtering Surgery; Follow-Up Studies; Glaucoma; Immunosuppressive Agents; Intraocular Pressure; Ophthalmic Solutions; Postoperative Complications; Prostheses and Implants; Rabbits | 1996 |
Renal fibrosis in cyclosporin A-treated renal allograft recipients: morphological findings in relation to renal hemodynamics.
Topics: Adolescent; Adult; Aged; Biopsy, Needle; Cyclosporine; Female; Fibrosis; Follow-Up Studies; Glomerular Filtration Rate; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Male; Middle Aged; Postoperative Complications; Renal Circulation | 1996 |
Expression of leucocyte chemoattractants by interstitial renal fibroblasts: up-regulation by drugs associated with interstitial fibrosis.
Topics: Animals; Chemokine CCL2; Chemokine CXCL10; Chemokines; Chemokines, CXC; Connective Tissue; Connective Tissue Cells; Cyclosporine; Cytokines; Fibroblasts; Fibrosis; Kidney; Nephritis, Interstitial; Puromycin Aminonucleoside; Rats; RNA, Messenger; Up-Regulation | 1996 |
Hepatic GVHD after HLA-haploidentical bone marrow transplantation in children with severe combined immunodeficiency: the effect of ursodeoxycholic acid.
Topics: Adrenal Cortex Hormones; Bile Duct Diseases; Bilirubin; Bone Marrow Transplantation; Cholagogues and Choleretics; Cyclosporine; Fibrosis; Graft vs Host Disease; Humans; Immunosuppressive Agents; Infant; Infant, Newborn; Liver Diseases; Male; Severe Combined Immunodeficiency; Skin Diseases; Ursodeoxycholic Acid | 1997 |
Heparin decreases blood pressure and response to exogenous endothelin but does not protect against chronic experimental cyclosporine nephropathy.
Topics: Animals; Arterioles; Blood Pressure; Cyclosporine; Endothelin-1; Fibrosis; Heparin; Immunosuppressive Agents; Kidney; Kidney Tubules; Male; Nephritis, Interstitial; Rats; Rats, Wistar | 1997 |
Sodium depletion enhances fibrosis and the expression of TGF-beta1 and matrix proteins in experimental chronic cyclosporine nephropathy.
Topics: Animals; Blood Pressure; Blotting, Northern; Creatinine; Cyclosporine; Extracellular Matrix Proteins; Fibrosis; Immunohistochemistry; Immunosuppressive Agents; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium; Transforming Growth Factor beta; Up-Regulation | 1997 |
Long-term low-dose cyclosporine therapy for psoriasis.
Topics: Age Factors; Biopsy; Creatinine; Cyclosporine; Fibrosis; Glomerular Filtration Rate; Humans; Hypertension; Immunosuppressive Agents; Kidney; Middle Aged; Psoriasis | 1997 |
Effect of immunosuppression on obliterative lesions in a heterotopic large-animal bronchial allograft model.
Topics: Animals; Azathioprine; Bronchi; Bronchiolitis Obliterans; Cartilage; Cyclosporine; Drug Therapy, Combination; Fibrosis; Immunosuppressive Agents; Inflammation; Methylprednisolone; Necrosis; Swine; Transplantation, Heterotopic; Transplantation, Homologous | 1997 |
Protective effects of dietary L-arginine supplementation on chronic cyclosporine nephrotoxicity.
Topics: Animals; Arginine; Blood Pressure; Cyclosporine; Enzyme Inhibitors; Fibrosis; Glomerular Filtration Rate; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Vascular Diseases | 1997 |
Periodontal management of gingival overgrowth in the heart transplant patient: a case report.
Topics: Calcium Channel Blockers; Candidiasis, Oral; Connective Tissue; Cyclosporine; Epithelium; Fibrosis; Follow-Up Studies; Gingival Hyperplasia; Gingival Hypertrophy; Gingival Overgrowth; Gingivectomy; Heart Transplantation; Humans; Immunosuppressive Agents; Male; Middle Aged; Nifedipine; Stomatitis | 1997 |
Accelerated apoptosis characterizes cyclosporine-associated interstitial fibrosis.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Apoptosis; Arginine; Biotin; Cyclosporine; Deoxyuracil Nucleotides; DNA Fragmentation; Enzyme Inhibitors; Fibrosis; Hydralazine; Immunosuppressive Agents; Ischemia; Kidney; Losartan; Macrophages; Male; Nephritis, Interstitial; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Staining and Labeling | 1998 |
[Renal biopsy in connection with long-term treatment of psoriasis with cyclosporine].
Topics: Adult; Aged; Biopsy; Cyclosporine; Female; Fibrosis; Glomerular Filtration Rate; Humans; Kidney; Male; Middle Aged; Psoriasis; Time Factors | 1998 |
Role of P-glycoprotein in chronic cyclosporine nephrotoxicity and its relationship to intrarenal angiotensin II deposits.
Topics: Angiotensin II; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Creatinine; Cyclosporine; Fibrosis; Immunosuppressive Agents; Kidney; Kidney Cortex; Kidney Tubules; Male; Rats; Rats, Sprague-Dawley | 1998 |
Tracheal allograft transplantation in rats: the role of immunosuppressive agents in development of obliterative airway disease.
Topics: Animals; Bronchiolitis Obliterans; Cyclosporine; Fibrosis; Graft Survival; Immunosuppressive Agents; Male; Mucous Membrane; Rats; Rats, Inbred Lew; Rats, Inbred Strains; Regeneration; Tacrolimus; Trachea; Transplantation, Heterotopic; Transplantation, Homologous | 1998 |
Diabetes mellitus after liver transplantation: a possible relation with the nutritional status.
Topics: Albuminuria; Bilirubin; Blood Glucose; Blood Proteins; C-Peptide; Cyclosporine; Diabetes Mellitus, Type 2; Fibrosis; Glucocorticoids; Humans; Hypoglycemic Agents; Immunosuppressive Agents; Insulin; Liver Transplantation; Male; Middle Aged; Nutritional Status; Prednisone; Radioimmunoassay; Triglycerides; Uric Acid | 1998 |
Unique changes in interstitial extracellular matrix composition are associated with rejection and cyclosporine toxicity in human renal allograft biopsies.
Topics: Biopsy; Chi-Square Distribution; Cyclosporine; Extracellular Matrix; Extracellular Matrix Proteins; Fibrosis; Graft Rejection; Humans; Immunosuppressive Agents; Kidney; Kidney Transplantation; Microscopy, Fluorescence; Pilot Projects; Transplantation, Homologous | 1999 |
Cyclosporin exerts a direct fibrogenic effect on human tubulointerstitial cells: roles of insulin-like growth factor I, transforming growth factor beta1, and platelet-derived growth factor.
Topics: Cell Survival; Cells, Cultured; Collagen; Culture Media, Conditioned; Cyclosporine; Female; Fibrosis; Gelatin; Humans; Immunosuppressive Agents; Insulin-Like Growth Factor I; Kidney Cortex; Kidney Tubules; Kidney Tubules, Proximal; Male; Metalloendopeptidases; Middle Aged; Platelet-Derived Growth Factor; Transforming Growth Factor beta | 1999 |
Myofibroblast proliferation, fibrosis, and defective pancreatic repair induced by cyclosporin in rats.
Topics: Actins; Acute Disease; Animals; Cell Division; Ceruletide; Collagenases; Cyclosporine; Fibrosis; Gastrointestinal Agents; Hydroxyproline; Immunosuppressive Agents; Male; Pancreas; Pancreatitis; Rats; Rats, Wistar; Regeneration; Transforming Growth Factor beta | 1999 |
A rat small bowel transplant model of chronic rejection: histopathologic characteristics.
Topics: Animals; Arteriosclerosis; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cyclosporine; Disease Models, Animal; Fibrosis; Graft Rejection; Graft Survival; Histocompatibility Antigens Class II; Immunohistochemistry; Intestine, Small; Macrophages; Male; Mesenteric Vascular Occlusion; Mesentery; Muscle, Smooth, Vascular; Rats; Rats, Inbred F344; Rats, Inbred Lew; Time Factors | 1999 |
Expression of apoptosis regulatory genes in chronic cyclosporine nephrotoxicity favors apoptosis.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blotting, Northern; Blotting, Western; Caspase 3; Caspases; Chronic Disease; Creatinine; Cyclosporine; Fas Ligand Protein; Fibrosis; Fluorescent Antibody Technique; Gene Expression Regulation, Enzymologic; Immunosuppressive Agents; In Situ Nick-End Labeling; Kidney Diseases; Male; Membrane Glycoproteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tumor Suppressor Protein p53; Weight Gain | 1999 |
Cyclosporine-induced interstitial fibrosis and arteriolar TGF-beta expression with preserved renal blood flow.
Topics: Animals; Arterioles; Cyclosporine; Fibrosis; Hemodynamics; Immunohistochemistry; Immunosuppressive Agents; Kidney; Male; Rats; Rats, Inbred Strains; Rats, Wistar; Renal Circulation; Transforming Growth Factor beta | 1999 |
Cyclosporin A prevents the histologic damage of antigen arthritis without inducing fibrosis.
Topics: Animals; Arthritis, Experimental; Cells, Cultured; Collagen; Cyclosporine; Disease Models, Animal; Fibrosis; Gene Expression; Joints; Macrophages; Platelet-Derived Growth Factor; Rabbits; RNA, Messenger; Staining and Labeling; Synovial Membrane; Transforming Growth Factor beta | 2000 |
Long-term clinical and pathological effects of cyclosporin in children with nephrosis.
Topics: Atrophy; Child; Child, Preschool; Cyclosporine; Fibrosis; Humans; Infant; Kidney; Kidney Tubules; Nephrosis, Lipoid; Retrospective Studies; Time Factors | 2000 |
Cyclosporin A inhibits cardiac hypertrophy and enhances cardiac dysfunction during postinfarction failure in rats.
Topics: Animals; Apoptosis; Cardiomegaly; Cyclosporine; Echocardiography; Fibrosis; Gene Expression; Heart; Heart Failure; Male; Myocardial Infarction; Myocardium; Pressure; Rats; Rats, Wistar; Renin; Ventricular Function, Left; Ventricular Remodeling | 2000 |
The role of renal sympathetic nerves in experimental chronic cyclosporine nephropathy.
Topics: Animals; Creatinine; Cyclosporine; Denervation; Diet, Sodium-Restricted; Fibrosis; Glomerular Filtration Rate; Inulin; Kidney; Kidney Cortex; Kidney Medulla; Male; Nephrectomy; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Systole | 2000 |
Cyclosporin: nephro-protective as well as nephrotoxic?
Topics: Animals; Cell Adhesion Molecules; Cyclosporine; Disease Models, Animal; Fibrosis; Gene Expression Regulation; Graft Rejection; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Transplantation; Rats; Serum Sickness; Tacrolimus; Transforming Growth Factor beta | 2000 |
Effect of nitric oxide modulation on TGF-beta1 and matrix proteins in chronic cyclosporine nephrotoxicity.
Topics: Animals; Arginine; Arterioles; Biglycan; Blood Pressure; Blotting, Northern; Chronic Disease; Collagen; Cyclosporine; Enzyme Inhibitors; Extracellular Matrix Proteins; Fibronectins; Fibrosis; Gene Expression; Glomerular Filtration Rate; Hyalin; Immunosuppressive Agents; Kidney Diseases; Kidney Glomerulus; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Plasminogen Activator Inhibitor 1; Proteoglycans; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transforming Growth Factor beta | 2000 |
Tacrolimus has less fibrogenic potential than cyclosporin A in a model of renal ischaemia-reperfusion injury.
Topics: Animals; Creatinine; Cyclosporine; Fibrosis; Gene Expression; Immunosuppressive Agents; Kidney Diseases; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Proteinuria; Rats; Rats, Wistar; Renal Artery; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; Tacrolimus; Transforming Growth Factor beta | 2000 |
Cyclosporine reduces left ventricular mass with chronic aortic banding in mice, which could be due to apoptosis and fibrosis.
Topics: Animals; Aorta; Apoptosis; Calcineurin; Calcineurin Inhibitors; Cell Size; Cyclosporine; Enzyme Inhibitors; Fibrosis; Hypertrophy, Left Ventricular; Injections, Subcutaneous; Iron; Ligation; Male; Mice; Mice, Inbred Strains; Myocardium; Time Factors | 2001 |
Connective tissue growth factor in drug-induced gingival overgrowth.
Topics: Adult; Antibodies; Anticonvulsants; Calcium Channel Blockers; Carrier Proteins; Coloring Agents; Connective Tissue; Connective Tissue Growth Factor; Cyclosporine; Endothelium, Vascular; Epithelium; Female; Fibroblasts; Fibrosis; Gingival Overgrowth; Growth Substances; Humans; Image Processing, Computer-Assisted; Immediate-Early Proteins; Immunoenzyme Techniques; Immunosuppressive Agents; Intercellular Signaling Peptides and Proteins; Leukocytes, Mononuclear; Male; Middle Aged; Mitogens; Neovascularization, Pathologic; Nifedipine; Phenytoin; Platelet Endothelial Cell Adhesion Molecule-1; Statistics, Nonparametric; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2001 |
Influence of the renin-angiotensin system on epidermal growth factor expression in normal and cyclosporine-treated rat kidney.
Topics: Angiotensin II; Animals; Apoptosis; Blood Pressure; Cyclosporine; Diet, Sodium-Restricted; Epidermal Growth Factor; Fibrosis; Immunohistochemistry; In Situ Nick-End Labeling; Kidney Glomerulus; Losartan; Male; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System | 2001 |
A case of tacrolimus nephrotoxicity appearing in a second renal transplantation patient.
Topics: Biopsy; Cyclosporine; Fibrosis; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Kidney; Kidney Transplantation; Male; Middle Aged; Renal Dialysis; Tacrolimus | 2001 |
Calcineurin inhibition attenuates mineralocorticoid-induced cardiac hypertrophy.
Topics: Aldosterone; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Atrial Natriuretic Factor; Body Weight; Calcineurin; Calcineurin Inhibitors; Cardiomegaly; Collagen Type III; Cyclosporine; Enzyme Inhibitors; Fibrosis; Heart; Immunosuppressive Agents; Losartan; Male; Mineralocorticoids; Myocardium; Nephrectomy; Organ Size; Rats; Rats, Inbred WKY; RNA, Messenger; Sodium Chloride, Dietary; Tacrolimus | 2002 |
Cyclosporin-related nephrotoxicity in children with nephrotic syndrome.
Topics: Child; Child, Preschool; Cyclosporine; Fibrosis; Humans; Immunosuppressive Agents; Infant; Kidney; Nephrotic Syndrome | 2002 |
Inhibition of endothelin-1 improves survival and vasculopathy in rat cardiac transplants treated with cyclosporine.
Topics: Animals; Aspartic Acid Endopeptidases; Cyclosporine; Endothelin-1; Endothelin-Converting Enzymes; Fibrosis; Glycopeptides; Graft Rejection; Graft Survival; Heart Transplantation; Immunosuppressive Agents; Male; Metalloendopeptidases; Myocardium; Rats; Rats, Inbred F344; Rats, Inbred Lew; Transplantation, Homologous | 2002 |
Effects of cyclosporine in osteopontin null mice.
Topics: Animals; Apoptosis; Cell Division; Cyclosporine; Fibrosis; Immunosuppressive Agents; Kidney; Macrophages; Mice; Mice, Knockout; Osteopontin; RNA, Messenger; Sialoglycoproteins; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2002 |
Hemolytic uremic syndrome in a patient with systemic sclerosis treated with cyclosporin A.
Topics: Acute Disease; Cyclosporine; Female; Fibrosis; Hemolytic-Uremic Syndrome; Humans; Kidney; Middle Aged; Scleroderma, Systemic | 1992 |
The effects of pentoxifylline on experimental chronic cyclosporine nephrotoxicity.
Topics: Animals; Cyclosporine; Fibrosis; Kidney; Kidney Diseases; Male; Pentoxifylline; Rats; Rats, Sprague-Dawley | 1992 |
Morphologic renal changes during cyclosporine treatment of psoriasis. Studies on pretreatment and posttreatment kidney biopsy specimens.
Topics: Adult; Biopsy; Creatinine; Cyclosporine; Female; Fibrosis; Humans; Kidney; Male; Middle Aged; Psoriasis | 1992 |