cyclosporine has been researched along with Carcinoma, Hepatocellular in 67 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 15 (22.39) | 18.2507 |
2000's | 34 (50.75) | 29.6817 |
2010's | 16 (23.88) | 24.3611 |
2020's | 2 (2.99) | 2.80 |
Authors | Studies |
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Abo-El Fetoh, ME; Akool, ES; Elnagar, MR; ElShafey, M; Ewees, M; Helal, GK; Saleh, IG | 1 |
Chen, YJ; Hsieh, CH; Huang, HL; Huang, YC; Tai, HC; Tsai, TH; Wang, LY | 1 |
González-Diéguez, ML; Houghton, RF; Mendoza Pacas, GE; Viso Vidal, D | 1 |
Gow, PJ; Grigg, SE; Sarri, GL; Yeomans, ND | 1 |
Dansako, H; Gu, W; Kato, N; Nishitsuji, H; Satoh, S; Shimotohno, K; Ueda, Y | 1 |
Baranyai, Z; Jakab, F; Jemnitz, K; Szabo, M; Veres, Z | 1 |
Bian, XL; Du, Q; Xu, XL; Yu, B; Zhai, Q; Zhu, B | 1 |
Chen, J; Chen, S; Gong, Z; Jiang, S; Li, L; Wang, J; Wei, Y; Yu, L; Zhang, M; Zhang, Y; Zhao, X | 1 |
Cucchetti, A; Del Gaudio, M; Grazi, GL; La Barba, G; Lauro, A; Pinna, AD; Ravaioli, M; Vivarelli, M | 1 |
Ge, YS; Jia, WD; Li, JS; Ma, JL; Wang, W; Wang, ZH; Xu, GL | 1 |
Dai, QS; Guo, QL; Hu, R; Liu, W; Lu, N; Mu, R; Nie, FF; Qi, Q; Rong, JJ; Wang, J; Wang, XT; Yang, Y; You, QD | 1 |
de Alaniz, MJ; de Gómez Dumm, IN; Lausada, N; Raimondi, JC | 1 |
Bai, Z; Du, X; Han, Y; Huan, T; Liu, L; Wang, Z; Wu, B; Zhang, J | 1 |
Lee, J | 1 |
Li, SW; Ling, X; Wen, L; Yan, B; Zhou, Y | 1 |
Borlak, J; Niehof, M | 1 |
Ballarin, R; Cautero, N; Cocchi, S; Codeluppi, M; D'Amico, G; De Ruvo, N; Di Benedetto, F; Gerunda, GE; Guaraldi, G; Guerrini, GP; Iemmolo, RM; Mimmo, A; Montalti, R; Rompianesi, G; Serra, V; Smerieri, N; Spaggiari, M; Tarantino, G | 1 |
Cai-Hong, Z; Fang, M; Jin-Hua, J; Li, H; Ning, W; Qing-Duan, W; Xiao-Juan, G; Yan, Z | 1 |
Jeon, YJ; Kim, YS | 1 |
Dong, C; He, M; Ren, R; Shao, C; Xie, Y; Ye, S; Yuan, D | 1 |
Goto, T; Koike, K; Kurokawa, M; Yamamoto, G; Yoshimi, A | 1 |
Alvarez Castro, AM; Castroagudín, JF; Molina Pérez, E; Seijo Ríos, S; Varo Pérez, E | 1 |
Lang, F; Loupatatzis, C; Schönfeld, P; Seitz, G; Siemen, D | 1 |
Caro, AA; Cederbaum, AI | 1 |
Aden, AA; Bellusci, R; Brillanti, S; Cavallari, A; Cavrini, G; Cucchetti, A; De Ruvo, N; La Barba, G; Vivarelli, M | 1 |
Lim, BG; Ng, KH; Wong, KP | 1 |
Chi, CW; Lin, HL; Liu, TY; Lui, WY | 1 |
Cheng, J; Hada, T; Imanishi, H; Jing, X; Ueki, N | 1 |
Jiang, GP; Li, MW; Xie, HY; Yang, FC; Zeng, QL; Zheng, SS | 1 |
Kido, H; Miyake, H; Okumura, Y; Sakai, M; Tashiro, S | 1 |
Jeon, YS; Jeong, ES; Kim, EK; Kim, KS; Kwon, KB; Lim, JG; Ryu, DG; Seo, EA; Shin, BC | 1 |
Bolondi, L; Cavallari, A; Cucchetti, A; La Barba, G; Pinna, AD; Piscaglia, F; Vivarelli, M | 1 |
Armstrong, JS; Cheung, NS; Halliwell, B; Rose, P; Siau, JL; Tan, GS; Whiteman, M | 1 |
Casadio, F; Corti, B; Croci, S; D'Errico Grigioni, A; Grigioni, WF; Landuzzi, L; Lollini, PL | 1 |
Buell, JF; Gross, TG; Woodle, ES | 1 |
Brunati, A; Cerutti, E; David, E; Franchello, A; Gennari, F; Lavezzo, B; Lupo, F; Marzano, A; Ottobrelli, A; Ricchiuti, A; Rizzetto, M; Romagnoli, R; Salizzoni, M; Schellino, MM; Strignano, P; Zamboni, F | 1 |
Dymkowska, D; Szczepanowska, J; Wieckowski, MR; Wojtczak, L | 1 |
Huang, YF; Li, LS; Li, Y; Liu, FY; Liu, ZH; Peng, YM | 1 |
Demirhan, B; Haberal, M; Kiyici, H; Nacar, A; Oğüş, E; Ozdemir, H; Zağyapan, R | 1 |
Cillo, U; Grazi, GL; Lake, J; Leonardi, L; Levy, G; Mies, S; Mühlbacher, F; Munn, S; Rossi, M; Samuel, D; Sanjuan, F; Villamil, F | 1 |
Bouchard, MJ; Clippinger, AJ; Lizzano, R; McClain, SL | 1 |
Bak, T; Campsen, J; Kam, I; Skibba, A; Trotter, JF; Wachs, M; Zimmerman, MA | 1 |
Li, D; Ma, CP; Qu, B; Sun, LH; Wan, J; Wang, W; Zhang, HQ; Zhang, SS | 1 |
Cheng, JC; Lai, HY; Yeh, CT; Yeh, YJ | 1 |
Kaplan, MM; Pedrosa, MC; Rohrer, RM | 1 |
Ascher, NL; Ferrell, LD; Hebert, M; Lake, JR; Nikolai, B; Roberts, JP | 1 |
Eramishantsev, AK; Goté, SV; Konstantinov, BA; Lebezev, VM; Lokshin, LS; Shertsinger, AG; Skipenko, OG; Tsirulńikova, OM | 1 |
de Wit, EC; Kaptein, A; Princen, HM | 1 |
Bosi, A; Grossi, A; Guidi, S; Rafanelli, D; Rossi-Ferrini, P; Saccardi, R; Statello, M; Vannucchi, AM | 1 |
Choi, JH; Chung, JB; Kim, BS; Kim, HS; Kim, JH; Kwon, OH; Lee, KS; Park, IS; Roh, JK; Yoo, NC | 1 |
Chen, CS; Chen, TC; Chu, SH; Huang, CC; Jeng, LB; Lai, MK | 1 |
Florén, CH; Rayyes, OA; Wallmark, A | 1 |
Berg, T; Fukomoto, T; Haller, GW; Hopf, U; Lemmens, HP; Lobeck, H; Mueller, AR; Naumann, U; Neuhaus, P; Platz, KP | 1 |
Bechstein, WO; Berg, T; Fukomoto, T; Guckelberger, O; Hopf, U; Lobeck, H; Mueller, AR; Neuhaus, P; Neuhaus, R; Platz, KP | 1 |
Bechstein, WO; Guckelberger, O; Jonas, S; Lobeck, H; Neuhaus, P; Neuhaus, R; Rayes, N; Riess, H; Schmidt, G; Tullius, SG; Vogl, T | 1 |
Köhler, H; Krüger, B; Riegel, W; Ulrich, C | 1 |
Goldstein, R; Klintmalm, G; Mues, G; Stone, MJ; Su, D; Tillery, GW; Tong, AW | 1 |
Fandrey, J; Jelkmann, W; Wördemann, M | 1 |
Berr, F; Hartwig, T; Hauss, J; Kohlhaw, K; Lübke, P; Schwarz, R | 1 |
Morrow, CS; Smitherman, PK; Townsend, AJ | 1 |
Ding, WX; Liu, J; Ong, CN; Shen, HM; Yang, CF | 1 |
Arenas, JI; García Bengoechea, M; Indart, A | 1 |
DePierre, JW; Grandér, D; Panaretakis, T; Shabalina, IG; Shoshan, MC | 1 |
Fujiwara, A; Mouri, H; Ogawa, S; Ohta, T; Sakaguchi, K; Sawayama, T; Senoh, T; Shiraga, K; Tsuji, T | 1 |
Gallyas, F; Sumegi, B; Varbiro, G; Veres, B | 1 |
Braunstein, G; Davison, AK; Feranchak, AP; Fitz, JG; Lomri, N; Mechetner, E; Roman, RM; Schwiebert, EM; Simeoni, LA | 1 |
Appelkvist, EL; Bäckman, L; Brunk, U; Sundberg, A; Teclebrhan, H | 1 |
4 review(s) available for cyclosporine and Carcinoma, Hepatocellular
Article | Year |
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Systematic review with meta-analysis: sirolimus- or everolimus-based immunosuppression following liver transplantation for hepatocellular carcinoma.
Topics: Calcineurin Inhibitors; Carcinoma, Hepatocellular; Cyclosporine; Everolimus; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Liver Neoplasms; Liver Transplantation; Neoplasm Recurrence, Local; Sirolimus; Tacrolimus; TOR Serine-Threonine Kinases | 2019 |
Hepatocellular carcinoma in cirrhotic liver with graft-versus-host disease.
Topics: Carcinoma, Hepatocellular; Catheter Ablation; Chronic Disease; Combined Modality Therapy; Cyclosporine; Embolization, Therapeutic; Esophageal and Gastric Varices; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Chronic-Phase; Liver Cirrhosis; Liver Neoplasms; Middle Aged; Postoperative Complications; Prednisolone | 2012 |
Malignancy after transplantation.
Topics: Azathioprine; Calcineurin Inhibitors; Carcinoma, Hepatocellular; Cyclosporine; Hepatitis, Viral, Human; Humans; Immunosuppressive Agents; Incidence; Kidney Transplantation; Lymphoproliferative Disorders; Mycophenolic Acid; Neoplasms; Sirolimus; Skin Neoplasms; Tacrolimus; Transplantation Immunology; Transplantation, Homologous | 2005 |
[Clinical studies in liver transplantation].
Topics: Carcinoma, Hepatocellular; Cyclosporine; Cytomegalovirus Infections; Double-Blind Method; Hepatitis B; Hepatitis C; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Liver Neoplasms; Liver Transplantation; Multicenter Studies as Topic; Postoperative Complications; Prognosis; Prospective Studies; Randomized Controlled Trials as Topic; Tacrolimus | 2000 |
1 trial(s) available for cyclosporine and Carcinoma, Hepatocellular
Article | Year |
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Long-term outcomes in liver transplant patients with hepatic C infection receiving tacrolimus or cyclosporine.
Topics: Adult; Carcinoma, Hepatocellular; Cyclosporine; Female; Follow-Up Studies; Hepatitis C; Humans; Immunosuppressive Agents; Liver Neoplasms; Liver Transplantation; Male; Middle Aged; Recurrence; Risk Factors; Tacrolimus; Time Factors; Treatment Outcome | 2006 |
62 other study(ies) available for cyclosporine and Carcinoma, Hepatocellular
Article | Year |
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Cyclosporin A activates human hepatocellular carcinoma (HepG2 cells) proliferation: implication of EGFR-mediated ERK1/2 signaling pathway.
Topics: ADAM17 Protein; Carcinoma, Hepatocellular; Cell Proliferation; Cyclosporine; Enzyme Activation; ErbB Receptors; Hep G2 Cells; Humans; Immunosuppressive Agents; Liver Neoplasms; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Reactive Oxygen Species; Signal Transduction | 2020 |
Robust combination of liver stereotactic body radiotherapy modulates pharmacokinetics of sorafenib toward preferable parameters.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Carcinoma, Hepatocellular; Cell Line, Tumor; Combined Modality Therapy; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Radiation; Enzyme Induction; Humans; Liver Neoplasms; Male; NF-kappa B; Portal Vein; Protein Kinase Inhibitors; Radiosurgery; Rats; Rats, Sprague-Dawley; Retrospective Studies; Sorafenib; Specific Pathogen-Free Organisms; Tissue Distribution; Venous Thrombosis | 2020 |
Tacrolimus-Induced Cholestatic Hepatitis in a Patient With Liver Transplant.
Topics: Allografts; Biopsy; Carcinoma, Hepatocellular; Cholestasis; Cyclosporine; Graft Rejection; Hepatitis; Humans; Immunosuppressive Agents; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Male; Middle Aged; Tacrolimus; Ultrasonography, Doppler | 2018 |
A new hepatoma cell line exhibiting high susceptibility to hepatitis B virus infection.
Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Cyclosporine; Hep G2 Cells; Hepatitis B; Hepatitis B virus; Host-Pathogen Interactions; Humans; Liver Neoplasms; Organic Anion Transporters, Sodium-Dependent; Rosiglitazone; Symporters; Virus Internalization | 2019 |
Comparison of human hepatoma HepaRG cells with human and rat hepatocytes in uptake transport assays in order to predict a risk of drug induced hepatotoxicity.
Topics: Animals; Biological Transport; Bosentan; Carcinoma, Hepatocellular; Cell Survival; Cells, Cultured; Chromans; Cyclosporine; Hepatocytes; Humans; Rats; Sulfobromophthalein; Sulfonamides; Taurocholic Acid; Thiazolidinediones; Troglitazone | 2013 |
Role of mitochondrial permeability transition in human hepatocellular carcinoma Hep-G2 cell death induced by rhein.
Topics: Adenosine Triphosphate; Anthraquinones; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Cyclosporine; Cytochromes c; Hep G2 Cells; Humans; In Situ Nick-End Labeling; Liver Neoplasms; Membrane Potential, Mitochondrial; Mitochondria; Permeability; Phytotherapy; Plant Extracts; Rheum | 2013 |
Cyclophilin J is a novel peptidyl-prolyl isomerase and target for repressing the growth of hepatocellular carcinoma.
Topics: Animals; Carcinoma, Hepatocellular; Chlorocebus aethiops; COS Cells; Cyclin D1; Cyclophilins; Cyclosporine; G1 Phase; Gene Expression Regulation, Neoplastic; HEK293 Cells; HeLa Cells; Hep G2 Cells; Humans; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; Protein Structure, Tertiary; S Phase; Up-Regulation; Xenograft Model Antitumor Assays | 2015 |
Liver transplantation for hepatocellular carcinoma under calcineurin inhibitors: reassessment of risk factors for tumor recurrence.
Topics: Adult; alpha-Fetoproteins; Calcineurin Inhibitors; Carcinoma, Hepatocellular; Cyclosporine; Female; Humans; Immunosuppressive Agents; Liver Neoplasms; Liver Transplantation; Male; Middle Aged; Neoplasm Recurrence, Local; Retrospective Studies; Risk Factors; ROC Curve; Sensitivity and Specificity; Tacrolimus | 2008 |
[Prevention of hepatic tumor growth and metastasis in rats with rapamycin].
Topics: Animals; Carcinoma, Hepatocellular; Cyclosporine; Disease Models, Animal; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Immunosuppressive Agents; Liver Neoplasms, Experimental; Male; Microvessels; Neoplasm Metastasis; Neovascularization, Pathologic; Random Allocation; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sirolimus; Vascular Endothelial Growth Factors | 2009 |
MAC-related mitochondrial pathway in oroxylin-A-induced apoptosis in human hepatocellular carcinoma HepG2 cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Cell Line, Tumor; Cyclosporine; Dimerization; Flavonoids; Humans; Ion Channels; Liver Neoplasms; Membrane Potential, Mitochondrial; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Membranes; Mitochondrial Permeability Transition Pore; Neoplasm Proteins; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Recombinant Fusion Proteins; RNA Interference; RNA, Small Interfering | 2009 |
Effect of cyclosporine and sirolimus on fatty acid desaturase activities in cultured HEPG2 cells.
Topics: Arachidonic Acids; Carcinoma, Hepatocellular; Cell Line, Tumor; Cyclosporine; Fatty Acid Desaturases; Fatty Acids; Humans; Immunosuppressive Agents; Kinetics; Linoleic Acid; Liver Neoplasms; Palmitic Acid; Sirolimus | 2009 |
Prolonged survival of human hepatocarcinoma cells in the liver of newborn C57BL/6 mice and resulting cellular xenorejection, especially the activation of hepatic natural killer T cells.
Topics: Age Factors; Animals; Animals, Newborn; Antigens, CD1d; Apoptosis; Carcinoma, Hepatocellular; CD3 Complex; Cell Survival; Cyclosporine; Graft Survival; Hep G2 Cells; Humans; Immunity, Cellular; Immunosuppressive Agents; Interferon-gamma; Interleukin-4; Liver; Liver Neoplasms; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Mice; Mice, Inbred C57BL; Natural Killer T-Cells; Neoplasm Transplantation; Spleen; Time Factors; Transplantation, Heterologous; Tumor Escape | 2010 |
Novel combinational treatment of cisplatin with cyclophilin A inhibitors in human heptocellular carcinomas.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Hypoxia; Cell Line, Tumor; Cell Survival; Cisplatin; Cyclophilin A; Cyclosporine; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Inhibitors; Humans; Immunosuppressive Agents; Lactones; Liver Neoplasms; Oxidative Stress; Reactive Oxygen Species; Spiro Compounds; Tumor Suppressor Protein p53; Up-Regulation | 2010 |
Modulation of mitochondrial permeability transition pore affects multidrug resistance in human hepatocellular carcinoma cells.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Atracurium; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Cell Line, Tumor; Cisplatin; Cyclosporine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Humans; Liver Neoplasms; Membrane Potential, Mitochondrial; Microscopy, Confocal; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore | 2010 |
HNF4alpha dysfunction as a molecular rational for cyclosporine induced hypertension.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Binding Sites; Carcinoma, Hepatocellular; Cell Line, Tumor; Computational Biology; Consensus Sequence; Cyclosporine; Gene Expression Regulation; Hepatocyte Nuclear Factor 4; Humans; Hypertension; Immunosuppressive Agents; NFATC Transcription Factors; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Transcription, Genetic | 2011 |
University of Modena experience in HIV-positive patients undergoing liver transplantation.
Topics: Adult; Antiretroviral Therapy, Highly Active; Carcinoma, Hepatocellular; CD4 Lymphocyte Count; Cyclosporine; Drug Substitution; End Stage Liver Disease; Female; Graft Rejection; Graft Survival; Hepatitis C, Chronic; HIV; HIV Infections; Hospitals, University; Humans; Immunosuppressive Agents; Italy; Kaplan-Meier Estimate; Liver Neoplasms; Liver Transplantation; Male; Middle Aged; Recurrence; RNA, Viral; Severity of Illness Index; Sirolimus; Tacrolimus; Time Factors; Treatment Outcome; Viral Load | 2011 |
Using rhodamine 123 accumulation in CD8 cells as a surrogate indicator to study the P-glycoprotein modulating effect of cepharanthine hydrochloride in vivo.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzylisoquinolines; Carcinoma, Hepatocellular; CD8-Positive T-Lymphocytes; Cyclosporine; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluorescent Dyes; Fluorouracil; Humans; Indicators and Reagents; Liver Neoplasms; Mice; Rhodamine 123; Tumor Cells, Cultured; Verapamil; Xenograft Model Antitumor Assays | 2011 |
Cyclosporin a inhibits albumin synthesis in Huh7 cells.
Topics: Blotting, Northern; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Culture Media, Conditioned; Cyclosporine; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Neoplastic; Humans; Hypoalbuminemia; Immunosuppressive Agents; Liver Neoplasms; RNA, Messenger; Serum Albumin; Time Factors | 2011 |
Cytochrome-c mediated a bystander response dependent on inducible nitric oxide synthase in irradiated hepatoma cells.
Topics: Bystander Effect; Carcinoma, Hepatocellular; Cell Line, Tumor; Coculture Techniques; Cyclosporine; Cytochromes c; Gamma Rays; Hep G2 Cells; Humans; Isothiuronium; Liver Neoplasms; Micronucleus Tests; Nitric Oxide; Nitric Oxide Synthase Type II; Reactive Oxygen Species; Signal Transduction | 2012 |
[Basiliximab in the treatment of acute steroid-resistant rejection after liver transplantation].
Topics: Acute Disease; Antibodies, Monoclonal; Basiliximab; Carcinoma, Hepatocellular; Cyclosporine; Drug Resistance; Graft Rejection; Humans; Immunosuppressive Agents; Liver Cirrhosis, Alcoholic; Liver Function Tests; Liver Neoplasms; Liver Transplantation; Male; Methylprednisolone; Middle Aged; Mycophenolic Acid; Pregnenediones; Receptors, Interleukin-2; Recombinant Fusion Proteins; Tacrolimus | 2012 |
Single-channel currents of the permeability transition pore from the inner mitochondrial membrane of rat liver and of a human hepatoma cell line.
Topics: Animals; Apoptosis; Calcium; Carcinoma, Hepatocellular; Cyclosporine; Dose-Response Relationship, Drug; Electrophysiology; fas Receptor; Humans; Intracellular Membranes; Ion Channels; Jurkat Cells; Liver Neoplasms; Membrane Potentials; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Patch-Clamp Techniques; Rats; Tumor Cells, Cultured | 2002 |
Ca2+-dependent and independent mitochondrial damage in HepG2 cells that overexpress CYP2E1.
Topics: alpha-Tocopherol; Arachidonic Acid; Calcium; Calpain; Carcinoma, Hepatocellular; Culture Media; Cyclosporine; Cysteine Proteinase Inhibitors; Cytochrome P-450 CYP2E1; Cytosol; Dipeptides; Humans; Intracellular Membranes; Iron; Lipid Peroxidation; Liver Neoplasms; Mitochondria, Liver; Oxidative Stress; Permeability; Tumor Cells, Cultured | 2002 |
Low recurrence rate of hepatocellular carcinoma after liver transplantation: better patient selection or lower immunosuppression?
Topics: Adult; Carcinoma, Hepatocellular; Cyclosporine; Disease-Free Survival; Female; Humans; Immunosuppressive Agents; Liver Neoplasms; Liver Transplantation; Male; Middle Aged; Neoplasm Recurrence, Local; Patient Selection; Postoperative Complications; Retrospective Studies; Risk Factors; Survival Rate | 2002 |
Sulfate conjugating and transport functions of MDCK distal tubular cells.
Topics: Animals; Biological Transport; Buthionine Sulfoximine; Carcinoma, Hepatocellular; Cell Line, Tumor; Cyclosporine; Glutathione; Harmine; Humans; Immunosuppressive Agents; Kidney Tubules, Distal; Leukotriene Antagonists; Liver; Membrane Transport Proteins; Methotrexate; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Organic Anion Transport Protein 1; Probenecid; Propionates; Quinolines; Radiation-Protective Agents; Radiation-Sensitizing Agents; Sulfates; Uricosuric Agents | 2003 |
Reversal of Taxol resistance in hepatoma by cyclosporin A: involvement of the PI-3 kinase-AKT 1 pathway.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Cyclosporine; Drug Interactions; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Inhibitors; Flow Cytometry; Humans; Liver Neoplasms; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, SCID; Mitochondria; Paclitaxel; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Tumor Cells, Cultured | 2003 |
Induction of apoptosis in hepatocellular carcinoma cell lines by emodin.
Topics: Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Caspase 9; Caspases; Catalase; Cell Cycle; Cell Death; Cell Division; Cyclosporine; DNA; DNA Fragmentation; Dose-Response Relationship, Drug; Emodin; Enzyme Inhibitors; Flow Cytometry; Humans; Hydrogen Peroxide; Membrane Potentials; Mitochondria; Oxidative Stress; Reactive Oxygen Species; Time Factors; Tumor Cells, Cultured | 2002 |
[Influence of combined cyclosporine A and tacrolimus with 5-fluorouracil on hepatocellular carcinoma rats].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Hepatocellular; Cyclosporine; Fluorouracil; Liver Neoplasms; Male; Membrane Potentials; Mitochondria; Necrosis; Rats; Rats, Wistar; Tacrolimus | 2003 |
Inhibitory effect of FK506 and cyclosporine A on the growth and invasion of human liver cancer cells.
Topics: Carcinoma, Hepatocellular; Cell Division; Cell Line, Tumor; Cyclosporine; Humans; Immunosuppressive Agents; Intercellular Adhesion Molecule-1; Liver Neoplasms; Neoplasm Invasiveness; Tacrolimus | 2004 |
Molecular mechanisms of apoptosis induced by Scorpio water extract in human hepatoma HepG2 cells.
Topics: Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Caspase 9; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cyclosporine; Cysteine Proteinase Inhibitors; Cytochromes c; Drugs, Chinese Herbal; Enzyme Inhibitors; Humans; Liver Neoplasms; Membrane Potentials; Mitochondria; Oligopeptides; Poly(ADP-ribose) Polymerases | 2005 |
Analysis of risk factors for tumor recurrence after liver transplantation for hepatocellular carcinoma: key role of immunosuppression.
Topics: Adult; Carcinoma, Hepatocellular; Cyclosporine; Disease-Free Survival; Female; Graft Rejection; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Liver Neoplasms; Liver Transplantation; Male; Middle Aged; Neoplasm Recurrence, Local; Risk Factors; ROC Curve | 2005 |
Hypochlorous acid-mediated mitochondrial dysfunction and apoptosis in human hepatoma HepG2 and human fetal liver cells: role of mitochondrial permeability transition.
Topics: Animals; Apoptosis; Bongkrekic Acid; Carcinoma, Hepatocellular; Caspase 3; Caspase 7; Caspases; Cell Line; Cell Line, Tumor; Cell Survival; Chemical and Drug Induced Liver Injury; Cyclosporine; Cytochromes c; Humans; Hypochlorous Acid; Liver; Membrane Potentials; Mitochondria, Liver; Mitochondrial Swelling; Permeability; Rats | 2005 |
Toward the definition of immunosuppressive regimens with antitumor activity.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Cyclosporine; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Isoxazoles; Jurkat Cells; Leflunomide; Liver Neoplasms; Mycophenolic Acid; Rhabdomyosarcoma; Sirolimus | 2005 |
The first one thousand liver transplants in Turin: a single-center experience in Italy.
Topics: Adolescent; Adult; Aged; Carcinoma, Hepatocellular; Child; Child, Preschool; Cyclosporine; Fibrosis; Graft Survival; Hepacivirus; Hepatitis B; Hepatitis B virus; Hepatitis C; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Infant; Italy; Liver Neoplasms; Liver Transplantation; Middle Aged; Models, Statistical; Time Factors; Treatment Outcome | 2005 |
Short-term and long-term effects of fatty acids in rat hepatoma AS-30D cells: the way to apoptosis.
Topics: Animals; Apoptosis; Arachidonic Acid; bcl-2-Associated X Protein; Calcium; Carcinoma, Hepatocellular; Caspase 3; Caspases; Cell Line, Tumor; Cell Respiration; Cyclosporine; Cytochrome c Group; Cytosol; Enzyme Activation; Enzyme Inhibitors; Fatty Acids; Flow Cytometry; Kinetics; Liver Neoplasms, Experimental; Membrane Potentials; Microscopy, Confocal; Mitochondria; Oleic Acid; Rats; Reactive Oxygen Species; Ultraviolet Rays | 2006 |
[Effects of tacrolimus and cyclosporine on albumin secretion in cultured human hepatocyte].
Topics: Albumins; Carcinoma, Hepatocellular; Cyclosporine; Hepatocytes; Humans; Interleukin-10; Interleukin-2; Interleukin-6; Liver Neoplasms; Tacrolimus; Tumor Cells, Cultured | 2006 |
Ultrastructural examination of glomerular and tubular changes in renal allografts with cyclosporine toxicity.
Topics: Adult; Carcinoma, Hepatocellular; Case-Control Studies; Cyclosporine; Female; Humans; Immunosuppressive Agents; Kidney Glomerulus; Kidney Transplantation; Kidney Tubules; Liver Neoplasms; Male; Retrospective Studies; Transplantation, Homologous | 2006 |
Hepatitis B virus replication is associated with an HBx-dependent mitochondrion-regulated increase in cytosolic calcium levels.
Topics: Calcium; Carcinoma, Hepatocellular; Cell Line, Tumor; Cyclosporine; Cytosol; DNA, Viral; Gene Expression Regulation; Gene Expression Regulation, Viral; Genome, Viral; Hepatitis B Antigens; Hepatitis B virus; Humans; Liver Neoplasms; Mitochondria; Virus Replication | 2007 |
Sirolimus-based immunosuppression following liver transplantation for hepatocellular carcinoma.
Topics: Adrenal Cortex Hormones; Calcineurin Inhibitors; Carcinoma, Hepatocellular; Cyclosporine; Drug Therapy, Combination; Female; Graft Rejection; Humans; Immunosuppressive Agents; Kaplan-Meier Estimate; Kidney Diseases; Liver Failure; Liver Neoplasms; Liver Transplantation; Male; Middle Aged; Mycophenolic Acid; Neoplasm Recurrence, Local; Proportional Hazards Models; Retrospective Studies; Risk Assessment; Sirolimus; Tacrolimus; Time Factors; Treatment Outcome | 2008 |
A novel benzotriazole derivative inhibits proliferation of human hepatocarcinoma cells by increasing oxidative stress concomitant mitochondrial damage.
Topics: Antineoplastic Agents; Antioxidants; Ascorbic Acid; Carcinoma, Hepatocellular; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclosporine; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Liver Neoplasms; Membrane Potential, Mitochondrial; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Oxidative Stress; Reactive Oxygen Species; Time Factors; Triazoles | 2008 |
Hepatitis C virus infection in mouse hepatoma cells co-expressing human CD81 and Sip-L.
Topics: Adaptor Proteins, Signal Transducing; Animals; Antigens, CD; Antiviral Agents; Carcinoma, Hepatocellular; Carrier Proteins; Cell Line, Tumor; Cyclosporine; Dioxygenases; Disease Models, Animal; Hepacivirus; Hepatitis C; Humans; Interferon-alpha; Liver; Mice; Mice, Nude; Phosphoproteins; Tetraspanin 28; Virus Replication | 2008 |
Alternate-day prednisone in the maintenance immunosuppressive therapy after orthotopic liver transplantation.
Topics: Adolescent; Adult; Aged; Azathioprine; Bile Duct Neoplasms; Carcinoma, Hepatocellular; Cholangiocarcinoma; Cholangitis, Sclerosing; Cushing Syndrome; Cyclosporine; Drug Administration Schedule; Female; Follow-Up Studies; Glucocorticoids; Graft Rejection; Hepatitis, Viral, Human; Humans; Immunosuppressive Agents; Incidence; Liver Cirrhosis; Liver Cirrhosis, Biliary; Liver Diseases, Alcoholic; Liver Failure, Acute; Liver Neoplasms; Liver Transplantation; Male; Middle Aged; Prednisone | 1995 |
Reversal of chronic rejection after treatment failure with FK506 and RS61443.
Topics: Adult; Carcinoma, Hepatocellular; Cyclosporine; Female; Graft Rejection; Hepatitis C; Humans; Immunosuppressive Agents; Liver Cirrhosis; Liver Function Tests; Liver Neoplasms; Liver Transplantation; Muromonab-CD3; Mycophenolic Acid; Tacrolimus | 1993 |
[Orthotopic liver transplantation (first clinical experience)].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Azathioprine; Carcinoma, Hepatocellular; Child; Cyclosporine; Female; Graft Rejection; Graft Survival; Humans; Immunosuppression Therapy; Liver Diseases; Liver Neoplasms; Liver Transplantation; Male; Middle Aged; Postoperative Complications; Reoperation; Time Factors | 1993 |
Cotranslational inhibition of apoB-100 synthesis by cyclosporin A in the human hepatoma cell line HepG2.
Topics: Apolipoprotein A-I; Apolipoprotein B-100; Apolipoproteins B; Carcinoma, Hepatocellular; Cyclosporine; Humans; Liver Neoplasms; Protein Biosynthesis; RNA, Messenger; Serum Albumin; Tumor Cells, Cultured | 1994 |
Effects of cyclosporin A on erythropoietin production by the human Hep3B hepatoma cell line.
Topics: Amino Acid Isomerases; Carcinoma, Hepatocellular; Carrier Proteins; Cyclosporine; Dose-Response Relationship, Drug; Erythropoietin; Gene Expression; Humans; In Vitro Techniques; Liver; Liver Neoplasms; Peptidylprolyl Isomerase; Protein Biosynthesis; RNA, Messenger; Tumor Cells, Cultured | 1993 |
Combined use of tamoxifen, cyclosporin A, and verapamil for modulating multidrug resistance in human hepatocellular carcinoma cell lines.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cyclosporine; Drug Resistance; Humans; Liver Neoplasms; Tamoxifen; Tumor Cells, Cultured; Verapamil | 1993 |
Unique triple malignancies following renal transplantation.
Topics: Carcinoma, Hepatocellular; Carcinoma, Transitional Cell; Cholangiocarcinoma; Cyclosporine; Fatal Outcome; Female; Humans; Immunosuppressive Agents; Kidney Transplantation; Liver Neoplasms; Middle Aged; Postoperative Complications; Prednisolone; Retrospective Studies | 1996 |
Cyclosporine inhibits catabolism of low-density lipoproteins in HepG2 cells by about 25%.
Topics: Carcinoma, Hepatocellular; Cyclosporine; Humans; Lipoproteins, LDL; Liver Neoplasms; Receptors, LDL; RNA, Messenger; Tumor Cells, Cultured | 1996 |
Hepatitis B recurrence in relation to immunosuppression and acute allograft rejection.
Topics: Acute Disease; Carcinoma, Hepatocellular; Cause of Death; Cyclosporine; Drug Therapy, Combination; Graft Rejection; Hepatitis B; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Incidence; Liver Neoplasms; Liver Transplantation; Recurrence; Retrospective Studies | 1996 |
Long-term follow-up in hepatitis C patients with respect to immunosuppression.
Topics: Carcinoma, Hepatocellular; Cyclosporine; Graft Rejection; Hepatitis C; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Incidence; Liver Neoplasms; Liver Transplantation; Postoperative Complications; Recurrence; Retrospective Studies; Survival Rate; Tacrolimus | 1996 |
Posttransplant malignancy and newer immunosuppressive protocols after liver transplantation.
Topics: Carcinoma, Hepatocellular; Cyclosporine; Follow-Up Studies; Hepatitis B; Hepatitis C; Humans; Immunosuppressive Agents; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Lymphoma; Neoplasms; Postoperative Complications; Retrospective Studies; Tacrolimus; Time Factors | 1996 |
Different effects of cyclosporine or tacrolimus on hepatocyte acute phase proteins.
Topics: Acute-Phase Proteins; Carcinoma, Hepatocellular; Cell Survival; Cyclosporine; Humans; Immunosuppressive Agents; L-Lactate Dehydrogenase; Liver; Liver Neoplasms; Serum Albumin; Tacrolimus; Transferrin; Tumor Cells, Cultured | 1998 |
Chemosensitization of human hepatocellular carcinoma cells with cyclosporin A in post-liver transplant patient plasma.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Cyclosporine; Cyclosporins; Doxorubicin; Humans; Immunosuppressive Agents; Liver Neoplasms; Liver Transplantation | 1996 |
Tumor necrosis factor-alpha production by human hepatoma cell lines is resistant to drugs that are inhibitory to macrophages.
Topics: Adjuvants, Immunologic; Carcinoma, Hepatocellular; Cyclosporine; Drug Resistance, Neoplasm; Humans; Liver Neoplasms; Macrophages; Pentoxifylline; Pregnanes; Taurine; Thalidomide; Thiadiazines; Tumor Necrosis Factor-alpha | 1998 |
Role of multidrug-resistance protein 2 in glutathione S-transferase P1-1-mediated resistance to 4-nitroquinoline 1-oxide toxicities in HepG2 cells.
Topics: 4-Nitroquinoline-1-oxide; ATP Binding Cassette Transporter, Subfamily B; Carcinogens; Carcinoma, Hepatocellular; Cell Division; Cyclosporine; Drug Resistance, Neoplasm; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Inactivation, Metabolic; Isoenzymes; Liver Neoplasms; Membrane Transport Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Protein Isoforms; Sulfinpyrazone; Transfection; Tumor Cells, Cultured | 2000 |
Superoxide radical-initiated apoptotic signalling pathway in selenite-treated HepG(2) cells: mitochondria serve as the main target.
Topics: Acetylcysteine; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Caspase Inhibitors; Caspases; Cyclic N-Oxides; Cyclosporine; Cytochrome c Group; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Glutathione; Humans; In Situ Nick-End Labeling; Kinetics; Liver Neoplasms; Membrane Potentials; Mitochondria; Signal Transduction; Sodium Selenite; Spin Labels; Superoxides; Trifluoperazine; Tumor Cells, Cultured | 2001 |
[Cyclosporin A, renal transplant and hepatocarcinoma].
Topics: Carcinoma, Hepatocellular; Cyclosporine; Fatal Outcome; Humans; Immunosuppressive Agents; Kidney Transplantation; Liver Neoplasms; Male; Middle Aged | 2000 |
Reactive oxygen species and mitochondria mediate the induction of apoptosis in human hepatoma HepG2 cells by the rodent peroxisome proliferator and hepatocarcinogen, perfluorooctanoic acid.
Topics: Acetylcysteine; Apoptosis; Caprylates; Carcinogens; Carcinoma, Hepatocellular; Caspase 9; Caspases; Cyclosporine; Dose-Response Relationship, Drug; Enzyme Activation; Flow Cytometry; Fluorocarbons; Humans; Hydrogen Peroxide; Kinetics; Liver Neoplasms; Membrane Potentials; Mitochondria, Liver; Reactive Oxygen Species; Superoxides; Tumor Cells, Cultured | 2001 |
Modulation of doxorubicin sensitivity by cyclosporine A in hepatocellular carcinoma cells and their doxorubicin-resistant sublines.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Cyclosporine; Doxorubicin; Drug Resistance; Drug Synergism; Humans; Liver Neoplasms; RNA, Messenger; Tumor Cells, Cultured | 2001 |
Direct effect of Taxol on free radical formation and mitochondrial permeability transition.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Calcium; Carcinoma, Hepatocellular; Cyclosporine; Cytochrome c Group; Dose-Response Relationship, Drug; Formazans; Free Radicals; Humans; Kidney; Membrane Potentials; Microscopy, Confocal; Mitochondria, Heart; Mitochondria, Liver; Oxygen; Paclitaxel; Permeability; Rats; Rats, Wistar; Reactive Oxygen Species; Tetrazolium Salts; Tumor Cells, Cultured | 2001 |
Evidence for multidrug resistance-1 P-glycoprotein-dependent regulation of cellular ATP permeability.
Topics: 3T3 Cells; Adenosine Triphosphate; Animals; Antibodies; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Sub-Family B Member 4; Carcinoma, Hepatocellular; Cell Membrane Permeability; Cell Size; Cells, Cultured; Chlorides; Cyclosporine; Humans; Mice; Rats; Tumor Cells, Cultured; Verapamil | 2001 |
Modulation of metabolism in HepG2 cells upon treatment with cyclosporin A and Nva2-cyclosporin.
Topics: Carcinoma, Hepatocellular; Carnitine O-Acetyltransferase; Catalase; Cholesterol; Cyclosporine; Cyclosporins; Dihydrolipoamide Dehydrogenase; Dolichols; Electron Transport Complex IV; Fatty Acid Desaturases; Glutathione Transferase; Humans; In Vitro Techniques; Lipid Metabolism; Liver Neoplasms; Microscopy, Electron; NADH Dehydrogenase; Palmitoyl Coenzyme A; Proteins; Time Factors; Tumor Cells, Cultured | 1991 |