cyclosporine has been researched along with Body Weight in 269 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.37) | 18.7374 |
| 1990's | 118 (43.87) | 18.2507 |
| 2000's | 120 (44.61) | 29.6817 |
| 2010's | 26 (9.67) | 24.3611 |
| 2020's | 4 (1.49) | 2.80 |
| Authors | Studies |
|---|---|
| Cho, HR; Kim, MS; Kim, YH; Kwon, B | 1 |
| Garncarczyk, A; Grabarek, BO; Michalska-Bańkowska, A; Wcisło-Dziadecka, D | 1 |
| Ding, XL; Liu, LN; Miao, LY; Tian, JX; Xue, L; Yan, HH; Zhang, JJ; Zhang, WJ; Zhang, WW | 1 |
| Hosono, H; Kawano, H; Matsumoto, Y; Ogami, C; Seki, H; To, H; Tsuji, Y | 1 |
| Bertrand, Y; Bleyzac, N; Ceraulo, A; Ducher, M; Leclerc, V | 1 |
| Bardazzi, F; Magnano, M; Odorici, G; Patrizi, A; Tengattini, V | 1 |
| Bae, J; Im, E; Jung, Y; Kim, MS; Lee, BL; Moon, HR; Naeem, M; Oshi, MA; Yoo, JW | 1 |
| Abbasi, MM; Argani, H; Dastmalchi, S; Ghasemi, B; Ghazizadeh, T; Ghorbanihaghjo, A; Karimi, P; Raeisi, S; Seifi, M | 1 |
| Feng, WY; Hu, L; Huang, L; Li, TF; Liu, XM; Luo, XX; Ma, XL; Wu, CF | 1 |
| Chen, SQ; Jacqz-Aigrain, E; Ni, SQ; Wang, J; Zeng, S; Zhao, W; Zhao, ZY | 1 |
| Lommer, MJ | 1 |
| Endo, A; Fujinaga, S; Hara, S; Murakami, H; Murano, Y; Nakagawa, M; Ohtomo, Y; Sakuraya, K; Shimizu, T; Someya, T | 1 |
| Albers, E; Brown, L; Kemna, M; Law, S; Notaro, E | 1 |
| Akbulut, S; Dogan, Z; Elbe, H; Eris, C; Otan, E; Toprak, G; Turkoz, Y; Yalcin, E | 1 |
| Devrim, AK; Essiz, D; Sozmen, M; Sudagidan, M | 1 |
| Baretta, GA; Gama Filho, O; Matias, JE; Toderke, EL; Tolazzi, AR | 1 |
| Elliott, MA; Jørgensen, HG; Kumar, MN; Oien, KA; Rhodes, S; Tekwe, CD; Venkatpurwar, VP | 1 |
| Boulos, AK; Herman, L; Okechuku, G; Upadhyay, K | 1 |
| Elger, DA; Gernert, M; Gey, L; Handreck, A; Mall, EM | 1 |
| Hiraki, Y; Iwanaga, N; Kasai, H; Mizoguchi, A; Ota, Y; Sonemoto, E; To, H; Tsuji, Y; Ueki, Y; Yukawa, E | 1 |
| Kasap, B; Kavukcu, S; Kiray, M; Kuralay, F; Sarioglu, S; Soylu, A; Tuğyan, K; Türkmen, M | 1 |
| Doyle, J; Dupuis, LL; Jin, M; Saunders, EF; Seto, W; Taylor, T | 1 |
| Amagai, M; Nishikawa, T; Takae, Y | 1 |
| Andriantsitohaina, R; Bianchi, R; Bonomini, F; Filippini, F; Pecháňová, O; Rezzani, R; Tengattini, S | 1 |
| Bañón-Maneus, E; Brault, Y; Burke, JT; Campistol, JM; Diekmann, F; Gutiérrez-Dalmau, A; Marcelo Arellano, E; Moya-Rull, D; Quintana, LF; Ramírez-Bajo, MJ; Revuelta, I; Rovira, J | 1 |
| Terao, T | 1 |
| Guo, J; Wang, W; Yan, F; Yao, L | 1 |
| Ayala, M; Buckel, E; Calabran, L; Fierro, A; Herzog, C; Morales, J | 1 |
| Allais, L; Barrow, PC; Condevaux, F; Fant, P | 1 |
| Fukuda, S; Hiraga, H; Ishiguro, Y; Kawaguchi, S; Nakane, A; Sakuraba, H; Satoh, Y | 1 |
| Fujinaga, S; Hara, S; Murakami, H; Ohtomo, Y; Shimizu, T; Someya, T; Umino, D | 1 |
| Des Rosiers, C; Fiskum, G; Hecker, PA; Khairallah, RJ; Kristian, T; Murphy, RC; O'Shea, KM; Robillard-Frayne, I; Sparagna, GC; Stanley, WC; Xu, W | 1 |
| Hu, X; Liu, H; Ren, L; Wang, W; Yin, H; Zhang, X; Zhang, Y | 1 |
| Backman, JT; Fanta, S; Holmberg, C; Hoppu, K; Jönsson, S; Karlsson, MO; Niemi, M | 1 |
| André, JL; Azougagh, S; Bensman, A; Brochard, K; Cloarec, S; Cochat, P; Deschênes, G; Fakhoury, M; Jacqz-Aigrain, E; Niaudet, P; Roussey, G; Tsimaratos, M; Zhao, W | 1 |
| Böhmer, AE; Brum, LM; Hansel, G; Portela, LV; Souza, DG; Souza, DO | 1 |
| Danhof, M; de Fijter, H; den Hartigh, J; Guchelaar, HJ; Ploeger, BA; Press, RR; van der Straaten, T; van Pelt, H | 1 |
| Chen, CC; Hsu, LW; Huang, LT; Huang, TL | 1 |
| Abrahams, AC; Blankestijn, PJ; Klein, IH; Ligtenberg, G; Oey, PL; van Ede, T | 1 |
| Muthuraman, A; Rana, A; Singh, A; Singh, J; Singla, SK; Sood, S | 1 |
| Gomonchareonsiri, S; Thamprasert, K; Wongmekiat, O | 1 |
| Muthuraman, A; Rana, A; Singh, A; Singla, SK; Sood, S | 1 |
| Arni, S; Inci, I; Jungraithmayr, W; Korom, S; Meerwein, C; Weder, W | 1 |
| Abboud, HE; Andoh, TF; Bagby, GC; Bennett, WM; Christianson, TA; Faulkner, GR; Jin, DC; Wahba, IM; Yang, CW | 1 |
| Chopra, K; Padi, SS | 2 |
| Chopra, K; Satyanarayana, PS | 1 |
| Castroagudin, JF; Conde, R; Delgado, M; González-Quintela, A; Mella, C; Otero, E; Padin, E; Segade, FR; Tomé, S; Varo, E | 1 |
| Gerhardt, U; Hillebrand, U; Hohage, H; Keuthage, W; Kobelt, V; Matzkies, FK; Suwelack, B | 1 |
| Aparicio, M; Barthe, N; Berger, F; Chauveau, P; El Haggan, W; Potaux, L; Vendrely, B | 1 |
| Abdelhalim, FM; Baron, PW; Concepcion, W; Cutler, D; Hasan, SM; Ojogho, ON; Sahney, S | 1 |
| Chamson-Reig, A; Libertun, C; Lux-Lantos, V; Schillaci, R; Sorianello, E | 1 |
| Collins, T; Howell, JM; O'Hara, AJ | 1 |
| Radio, SJ; Roberts, CA; Stern, DL | 1 |
| Althoff, J; Ewe, S; Richter-Reichhelm, HB; Schulte, A | 1 |
| Blanco, G; Diebold, Y; Domingo, E; Fernández, N; Lopez, R; Mayo-Iscar, A; Morilla-Grasa, A; Ordoñez, JL; Rabano, G; Saornil, MA | 1 |
| Bräutigam, M; Christophers, E; Kaufmann, R; Paul, C; Thaçi, D; Weidinger, G | 1 |
| Klaus, A; Klima, G; Margreiter, R; Offner, FA; Pernthaler, H | 1 |
| Ahn, HJ; Bang, BK; Cha, JH; Jung, JY; Kim, J; Kim, WY; Kim, YS; Li, C; Yang, CW; Yoon, SA | 1 |
| Chen, D; Gartley, CJ; Harvey, SJ; Jacobs, RM; Jefferson, B; Thorner, PS; Zheng, K | 1 |
| Fujimura, A; Nishiki, K; Purkerson, JM; Schwartz, GJ; Tsuruoka, S; Wakaumi, M; Yamamoto, H | 1 |
| Beauchamp, D; Gourde, P; Grenier, L; Labrecque, G; LeBrun, M; Plante, I; Pons, M; Simard, M; Thibault, L | 1 |
| Echizen, H; Kanamori, M; Takahashi, H | 1 |
| Artz, MA; Blom, HJ; Boots, JM; Christiaans, MH; Demacker, PN; Hilbrands, LB; Ligtenberg, G; Roodnat, JI; Sweep, FC; Vos, PF | 1 |
| Bauer, AJ; Ishikawa, T; Iwanami, K; Moore, BA; Murase, N; Nalesnik, MA; Neto, JS; Okuda, T; Türler, A; Venkataramanan, R; Zhu, Y | 1 |
| Davis, NA; Inman, SR; Lukaszek, VA; Olson, KM | 1 |
| Hamada, K; Hirosumi, J; Hosogai, N; Manda, T; Mutoh, S; Ogawa, T; Tomita, M | 1 |
| Ihara, K; Ikeda, K; Kawai, S; Merida, L; Ohno, T; Shigetomi, M; Sugiyama, T; Tsubone, T | 1 |
| Baumlin, Y; Hof, A; Hof, RP; Matsumoto, Y | 1 |
| Brown, TP; Kim, Y; Pantin-Jackwood, MJ | 1 |
| Broering, DC; Burdelski, M; Ganschow, R; Grabhorn, E; Hinrichs, B; Mir, TS; Richter, A; Rogiers, X; Schulz, A; von Hugo, A | 1 |
| Angelini, A; Caforio, AL; Feltrin, G; Fortina, AB; Gambino, A; Gerosa, G; Iliceto, S; Piaserico, S; Ramondo, A; Thiene, G; Tona, F; Valente, M | 1 |
| Campos, Hde H; Carvalho, RA; Farias, IN; Moraes, ME; Moraes, MO; Mota, RS; Silva, SF; Silva, SL | 1 |
| Csiszar, K; Elmér, E; Fong, KS; Hansson, MJ; Karlsson, J; Keep, MF | 1 |
| Broering, DC; Burdelski, M; Ganschow, R; Grabhorn, E; Helmke, K; Hinrichs, B; Rogiers, X; Schulz, A | 1 |
| Chou, NK; Ko, WJ; Wang, CH; Wang, SS | 1 |
| Dietert, RR; Fitch, KJ; Hussain, I; Marsh, JA; Piepenbrink, MS | 1 |
| Christensen, ND; Cladel, NM; Hu, J; Peng, X; Pickel, MD | 1 |
| Andreetta, F; Arnoldi, E; Burdi, R; Camerino, C; Confalonieri, P; Conte Camerino, D; Courdier-Fruh, I; De Luca, A; Didonna, MP; Fraysse, B; Frigeri, A; Liantonio, A; Magyar, JP; Mangieri, D; Nico, B; Pierno, S; Pisoni, M; Rolland, JF; Svelto, M; Zallone, A | 1 |
| Ebel, H; Grebe, SO; Lange, H; Mueller, TF; Troeltsch, M | 1 |
| Almaraz, A; Blanco, G; Fernández, N; López-Velasco, R; Morilla-Grasa, A; Ordóñez, JL; Rábano, G; Saornil-Alvarez, MA | 1 |
| Aoki, MS; Miyabara, EH; Moriscot, AS; Soares, AG | 1 |
| Ellis, JS; Seymour, RA; Thomason, JM | 1 |
| Backman, JT; Fanta, S; Holmberg, C; Hoppu, K; Seikku, P | 1 |
| Deters, M; Kaever, V; Kirchner, G; Koal, T; Resch, K | 1 |
| Coombes, JS; Fassett, RG; Fletcher, LA; Richards, RS | 1 |
| Allard, C; Coquerel, A; Debruyne, D; El Haggan, W; Ficheux, M; Hurault de Ligny, B; Lobbedez, T; Rognant, N; Ryckelynck, JP | 1 |
| Castagneto, M; Friman, S; Klinger, M; Martinek, A; Nonnast-Daniel, B; Russ, GR; Scheuermann, EH; Tuncer, M; Vincenti, F; Wiecek, A | 1 |
| Kaczmarski, M; Konstantynowicz, J; Malyszko, J; Malyszko, JS; Mysliwiec, M; Pawlak, K; Wolczynski, S | 1 |
| Arai, C; Ohnuki, Y; Saeki, Y; Umeki, D | 1 |
| Coombes, JS; Fassett, RG; Lexis, LA; Richards, RS | 1 |
| Aoki, MS; Miyabara, EH; Moriscot, AS; Saito, ET; Soares, AG | 1 |
| Moghadasian, MH | 1 |
| Arafa, M; El Etter, E; Hagar, HH | 1 |
| Bigard, X; Chapot, R; Koulmann, N; N'Guessan, B; Peinnequin, A; Sanchez, H; Serrurier, B; Ventura-Clapier, R | 1 |
| Andriantsitohaina, R; Bianchi, R; Bonomini, F; Kojsová, S; Pechánová, O; Rezzani, R; Rodella, LF; Tengattini, S | 1 |
| Akhunlar, H; Güven, H; Kavukçu, S; Sarioglu, S; Soylu, A; Türkmen, MA; Yilmaz, O | 1 |
| Choi, JS; Chung, SJ; Koo, HH; Lee, SH; Sung, KW; Yoo, KH | 1 |
| Blanco, JA; Bobadilla, NA; Bonventre, JV; Cruz, C; Gamba, G; Pérez-Rojas, J; Trujillo, J; Uribe, N; Vaidya, VS | 1 |
| Barrow, PC; Horand, F; Ravel, G | 1 |
| Belitsky, P; Foote, CJ; Fraser, A; Greer, W; Kiberd, BA; Lawen, J; Nashan, B | 1 |
| Bueno, V; Burdmann, EA; Cury, PM; Silva, FR; Silva, LB | 1 |
| Câmara, NO; Campaholle, G; Cenedeze, MA; de Paula Antunes Teixeira, V; dos Reis, MA; Pacheco-Silva, A; Pereira, MG | 1 |
| Irtan, S; Jacqz-Aigrain, E; Leroy, V; Marquet, P; Rousseau, A; Saint-Marcoux, F; Zhang, D | 1 |
| Coakley, JC; Earl, JW; McLachlan, AJ; Nath, CE; Shaw, PJ | 1 |
| Fujimura, A; Ioka, T; Kaneda, T; Maeda, A; Tsuruoka, S | 1 |
| Gondo, T; Hashimoto, T; Matsunaga, T; Shigetomi, M; Sugiyama, T; Suzuki, H; Taguchi, T; Tanaka, H | 1 |
| Amudha, G; Josephine, A; Preetha, SP; Sundarapandian, R; Varalakshmi, P; Veena, CK | 1 |
| Canter, C; Hmiel, SP; Lassa-Claxton, S; Nadler, M; Shepherd, R | 1 |
| Chan, E; Lou, HX; Vathsala, A; Yau, WP | 1 |
| Baken, KA; Breit, TM; de Vries, A; Jonker, MJ; Pennings, JL; Schaap, MM; van Loveren, H; van Steeg, H | 1 |
| Knapik, P; Nadziakiewicz, P; Pacholewicz, J; Urbańska, E; Zakliczyński, M; Zembala, M | 1 |
| Azordegan, N; Fischer, G; Jassal, DS; Le, K; Moghadasian, MH; Othman, RA; Riediger, N; Suh, M | 1 |
| Bette, M; Dünne, AA; Häussler, U; Heverhagen, JT; Mandic, R; Neubauer, A; Schulz, S; Weihe, E; Werner, JA | 1 |
| Leelarugrayub, N; Thamprasert, K; Wongmekiat, O | 1 |
| Anveden-Hertzberg, L; Sonnino, RE | 1 |
| De Waal, EJ; Dortant, PM; Kranjc, MA; Timmerman, HH; Van Loveren, H | 1 |
| Cvetkovic, M; Epstein, S; Jee, WS; Liang, XG; Ma, Y; Mann, GN; Romero, DF | 1 |
| Henry, TR; Solem, LE; Wallace, KB | 1 |
| Bariety, J; Darlametsos, I; Gkikas, G; Hornych, A; Morphake, P; Papanikolaou, N; Tsipas, G | 1 |
| Andersen, HO; Hansen, BF; Holm, P; Kjeldsen, K; Nordestgaard, BG; Stender, S | 1 |
| Holmberg, C; Koistinen, R; Laine, J; Sarna, S; Sipila, I | 1 |
| Aridge, D; Bastani, B; Garvin, PJ; Heisler, T; Lindsey, L; Puntney, G; Robinson, S; Solomon, H | 1 |
| Chadwick, B; del Fierro, GM; Meers, J; Park, HS; Robinson, WF; Thomas, J | 1 |
| Baba, M; Fujisawa, T; Saitoh, Y; Sekine, Y; Takeda, T; Urabe, N; Yamaguchi, Y | 1 |
| Hartmann, A; Jungmann, E; Kaltenbach, M; Kober, G; Schoeppe, W; Schwietzer, GK; Stratmann, D | 1 |
| Doi, K; Kawai, S; Muramatsu, K | 1 |
| Armstrong, EC; Bryer, HP; Buchinsky, FJ; Epstein, S; Isserow, JA; Mann, GN; Romero, DF; Rucinski, B | 1 |
| Hilbrands, LB; Hoitsma, AJ; Koene, RA | 1 |
| Eggermont, AM; Jonker, AM; Marquet, RL; Van de Vrie, W | 1 |
| Li, M; Martin, A; Turner, SW; Whitworth, JA; Wong, KS | 1 |
| Cohan, J; Fabrega, AJ; Meslar, P; Pollak, R | 1 |
| Exner, V; Grotz, W; Gugel, B; Mundinger, A; Reichelt, A; Schollmeyer, P | 1 |
| Basile, GC; Corbetta, G; Gusmano, R; Perfumo, F; Piaggio, G; Verrina, E | 1 |
| Broyer, M; Cabiac, MD; Gagnadoux, MF; Guest, G; Humbert, H; Niaudet, P; Said, MB | 1 |
| Kajiwara, R; Kamataki, T; Kawaguchi, Y; Nagayama, S; Yokoi, T | 1 |
| Chau, KF; Li, CS; Mak, CK | 1 |
| Armstrong, EC; Buchinsky, FJ; Epstein, S; Jacobs, TW; Jee, WS; Ke, HZ; Li, M; Ma, YF; Mann, GN | 1 |
| Majoor, GD; Van Breda Vriesman, PJ; Wodzig, KW | 1 |
| Bennett, WM; Holcomb, S; McCarron, DA; Roullet, JB; Xue, H | 1 |
| Bock, HA; Brunner, FP; Kamber, V; Thiel, G | 1 |
| Jeffery, JJ; Penner, SB; Smyth, DD | 1 |
| Goto, M; Hamaguchi, H; Hisama, N; Kikuchi, N; Makino, Y; Mori, K; Ogawa, M; Takata, N; Yamaguchi, Y | 1 |
| Brown, PA; Heys, SD; Shaikh, MG; Whiting, PH | 1 |
| Endoh, H; Kobayashi, A; Kodama, T; Kurosawa, M; Nozue, T; Sako, A; Satoh, T; Takagi, Y; Uemasu, F; Yamazaki, H | 1 |
| Brodsky, G; Darrell, J; Strome, M; Strome, S; Wu, J | 1 |
| Grieve, EM; Hawksworth, GM; Simpson, JG; Whiting, PH | 1 |
| Bidani, AK; Churchill, MC; Churchill, PC | 1 |
| Horber, FF; Jaeger, P; Jensen, EX; Lippuner, K; Montandon, A; Steiger, U | 1 |
| Barthelmebs, M; Billing, A; Fabre, M; Grima, M; Hofner, M; Imbs, JL; Krieger, JP; Stephan, D | 1 |
| Andoh, TF; Bennett, WM; Gardner, MP; Houghton, DC; Lindsley, J | 1 |
| Fujihira, S; Fujii, T; Fujimoto, Y; Hisatomi, A; Mine, Y; Ohara, K | 1 |
| Bennett, WM; Brunner, LJ; Koop, DR | 1 |
| Amici, G; Calconi, G; Chiara, G; Maresca, MC; Pignata, G; Vianello, A | 1 |
| Benedetti, E; Fryer, JP; Gruessner, A; Gruessner, RW; Hakim, N; Moon, C; Nakhleh, RE; Pirenne, J; Troppmann, C | 1 |
| Andoh, TF; Bennett, WM; Border, WA; Franceschini, N; Noble, NA; Shihab, FS; Tanner, AM | 1 |
| Kim, JY; Suh, KS | 1 |
| Hardy, KJ; Shulkes, A; Tancheroen, S | 1 |
| Baluarte, HJ; Caputo, GC; Cooney, G; Dunn, S; Goldsmith, B; Kaiser, BA; Lum, B; Mochon, M; Polinsky, MS | 1 |
| Berkenboom, G; Brékine, D; Carpentier, Y; Fontaine, J; Richelle, M; Unger, P | 1 |
| Bley, N; Classen, HG; Dick, K; Gobel, Y; Lebeau, A; Nobiling, R; Rob, PM; Rohwer, J; Sack, K; Schmid, H; Weigelt, I | 1 |
| Junaid, TA; Owunwanne, A; Shihab-Eldeen, A; Yacoub, T | 1 |
| Bergmann, BM; Gilliland, MA; Quintans, J; Rechtschaffen, A | 1 |
| Hikichi, N; Iizuka, Y; Murata, R; Ogata, M | 1 |
| Aiko, S; Conner, EM; Fuseler, JA; Grisham, MB | 1 |
| Chang, CT; Charnick, SB; Hwang, DS; Jin, J; Meligeni, J; Moore, MA; Nedelman, JR; Wong, R | 1 |
| De Lima, JJ; Diament, J; Krieger, EM; Latrilha, Mda C; Maranhão, RC; Pileggi, F; Romão, JE | 1 |
| Buckley, P; Crevel, RW; Robinson, JA; Sanders, IJ | 1 |
| Chong, AS; Foster, P; Gebel, H; Guo, Z; Jensik, SC; McChesney, L; Mital, D; Sankary, HN; Shen, J; Williams, JW | 1 |
| Bowman, AR; Epstein, S; Liss, T; Ma, YF; Pan, Z; Popoff, SN; Rucinski, B; Sass, DA | 1 |
| Bowman, AR; Dissanayake, IR; Epstein, S; Jee, WS; Liang, H; Ma, YF; Sass, DA; Yuan, Z | 1 |
| Ferron, GM; Jusko, WJ; Mishina, EV; Zimmerman, JJ | 1 |
| Amador, AG; Bartke, A; Esquifino, AI; Villanúa, MA | 1 |
| Boz, A; Kaputlu, I; Karayalçin, B; Sadan, G | 1 |
| Furlanut, M; Wu, G | 2 |
| Dauwe, SE; De Broe, ME; Duymelinck, C; Nouwen, EJ; Verpooten, GA | 1 |
| Arlt, M; Brückner, D; Dietl, KH; Hohage, H; Spieker, C; Zidek, W | 1 |
| Adams, TF; Daly, RC; Edwards, BS; Frantz, RP; McGregor, CG; Olson, LJ; Rodeheffer, RJ; Schwab, MK; Textor, SC | 1 |
| Bowman, AR; Epstein, S; Jee, WS; Ma, Y; Sass, DA; Yuan, Z | 1 |
| Hof, A; Hof, RP; Joergensen, J; Rudin, M; Wehr, S | 1 |
| Grigg, A; Harun, MH; Szer, J | 1 |
| Baumann, K; Hannemann, J; Krüger, S; Wunderle, W; Yousif, T | 1 |
| Andersen, HO; Nordestgaard, BG; Qvortrup, K; Rostgaard, J | 1 |
| Brunner, W; Irschik, H; Klauser, RM; Kletzmayr, J; Kovarik, J; Sturm, I; Woloszczuk, W | 1 |
| Chao, C; Chao, J; Chao, L; Ford, P; Wang, C | 1 |
| Canzanello, VJ; Krom, RA; Porayko, MK; Schwartz, L; Taler, SJ; Textor, SC; Wiesner, RH | 1 |
| Byrt, T; Kilpatrick, NM; Lucas, JO; Shipp, A; Weintraub, RG; Wilkinson, JL | 1 |
| Erben, RG; Gärtner, R; Stangassinger, M | 1 |
| Arribas, I; de Arriba, G; Parra, T; Perez de Lema, G; Rodriguez-Puyol, D; Rodriguez-Puyol, M | 1 |
| Auch-Schwelk, W; Fleck, E; Jautzke, G; Unkelbach, E; Unkelbach, M | 1 |
| Chueh, SC; Kahan, BD | 1 |
| Biring, MS; Fournier, M; Lewis, MI; Ross, DJ | 1 |
| Canzanello, VJ; Krom, RA; Porayko, MK; Schwartz, LL; Taler, SJ; Textor, SC; Wiesner, RH | 1 |
| Ashley, FP; Koffman, CG; Morel, A; Ogg, CS; Rigden, SP; Smith, D; Wilson, RF | 1 |
| Fujimura, A; Ishii, M; Kobayashi, E; Sugimoto, K; Tsuruoka, S; Yabana, M; Yamauchi, H | 1 |
| Banijamali, HS; Benediktsson, H; Paul, LC; ter Keurs, HE; ter Keurs, MH | 1 |
| Ishiyama, N; Kanno, K; Naito, K; Nishiyama, S; Okumura, F; Toriumi, W | 1 |
| Foda, MA; Ghoneim, M; Moustafa, F; Sabry, A; Sally, S; Sobh, M | 1 |
| Donatsch, P; Dorobek, B; Jaffee, B; Magolda, R; Pally, C; Papageorgiou, C; Schuurman, HJ; Smith, D; Zehender, H | 1 |
| Richter-Reichhelm, HB; Schulte, AE | 1 |
| Balogh, A; Fleck, C; Kostka, E; Kühl, A; Kuhn, UD; Lupp, A; Stein, G | 1 |
| Kim, MS; Kim, SI; Kim, YS; Moon, JI; Park, K | 1 |
| Fukui, RT; Ianhez, LE; Menegazzo, LA; Rocha, DM; Sabbaga, E; Silva, ME; Ursich, MJ; Wajchenberg, BL | 1 |
| Berry, GJ; Boeke, K; Christians, U; Gummert, JF; Hausen, B; Morris, RE | 1 |
| Arimori, K; Nakano, H; Urata, T | 1 |
| Horiuchi, M; Jalil, A; Kobayashi, K; Nomoto, M; Saheki, T | 1 |
| Benet, LZ; Berry, GJ; Boeke, K; Christians, U; Hausen, B; Morris, RE; Segarra, I | 1 |
| Clarke, H; Ryan, MP | 1 |
| Karppanen, H; Krogerus, L; Lähteenmäki, T; Lassila, M; Mervaala, E; Vapaatalo, H; Vaskonen, T | 1 |
| Chávez, R; Jamieson, N; Metcalfe, A; Metcalfe, S; Nivatvongs, S; Pino, G; Romero, D; Takamori, S; Watson, C | 1 |
| Aramaki, M; Kawano, K; Kim, YI; Kitano, S; Morii, Y; Yoshida, T | 1 |
| Fogh-Andersen, N; Hansen, JM; Johansen, NJ; Mollerup, HM; Strandgaard, S | 1 |
| Berry, GJ; Christians, U; Gummert, J; Hausen, B; Hook, L; Ikonen, T; Legay, F; Morris, RE; Schreier, MH; Schuler, W; Serkova, N | 1 |
| Bräutigam, M; Czech, W; Schöpf, E; Weidinger, G | 1 |
| de Bruin, RW; Dowling, J; Jablonski, P; Jin, XJ; Kouwenhoven, EA; Maguire, JA; Stein-Oakley, AN; Thomson, NM | 1 |
| Amano, A; Daikoku, H; Fujimori, Y; Fukui, N; Morisaki, I; Murakami, J | 1 |
| Bigard, X; Mateo, P; Rousseau, V; Sanchez, H; Veksler, V; Ventura-Clapier, R; Zoll, J | 1 |
| Fassit, JC; Gómez Dumm, IN; Raimondi, C; Touceda, L | 1 |
| Finckenberg, P; Lassila, M; Nurminen, ML; Pere, AK; Vapaatalo, H | 1 |
| Hayashida, W; Kihara, Y; Sasayama, S; Yasaka, A | 1 |
| Ahonen, J; Finckenberg, P; Krogerus, L; Lassila, M; Nurminen, ML; Pere, AK; Vapaatalo, H | 1 |
| Aketa, M; Goto, T; Inoue, T; Kawamura, I; Mabuchi, M; Matsuo, M; Seki, J | 1 |
| Bobadilla, NA; Bolio, A; Gamba, G; Herrera-Acosta, J; Jiménez, F; Sánchez-Lozada, LG | 1 |
| Chin, ER; Dunn, SE; Michel, RN | 1 |
| Darlametsos, IE; Papanikolaou, EN; Varonos, DD | 1 |
| Clementi, G; Cutuli, VM; Fiore, CE; Messina, R; Pennisi, P; Prato, A | 1 |
| Blanco, G; Diebold, Y; Domingo, E; López, R; Rábano, G; Saornil, AM; Tutor, CJ | 1 |
| Dissanayake, IR; Epstein, S; Goodman, GR; Gorodetsky, E; Jee, WS; Lu, J; Ma, YF; Sodam, BR | 1 |
| Amico-Roxas, M; Caruso, A; Clementi, G; Cutuli, VM; Fiore, CE; Mangano, NG; Matera, M; Pennisi, P; Prato, A | 1 |
| Achilleos, O; Candinas, D; D'Silva, M; Dalgic, A; Lee, SJ; Mayer, AD; McMaster, P; Miki, C | 1 |
| Awumey, EM; Epstein, S; Sampson, WH; Sodam, BR | 1 |
| Baumlin, Y; Hof, A; Hof, RP; Nikolova, Z | 1 |
| Chou, TC; Clark, J; Kahan, BD; Napoli, KL; Podder, H; Stepkowski, SM; Verani, RR | 1 |
| Heemann, U; Müller, V; Szabó, A; Viklický, O; Vitko, S; Zou, H | 1 |
| Bai, S; Brunner, LJ; Kahan, BD; Napoli, KL; Stepkowski, SM | 1 |
| Alexander, GJ; Gibbs, P; Gimson, AE; Neal, DA | 1 |
| Benet, LZ; Christians, U; Jacobsen, W; Leibfritz, D; Litt, L; Niemann, CU; Serkova, N | 1 |
| López-Calderón, A; Martín, AI; Soto, L; Vara, E | 1 |
| Chopra, K; Satyanarayana, PS; Singh, D | 1 |
| Goto, T; Hosogai, N; Seki, J | 1 |
| Arita, S; Kasraie, A; Mullen, Y; Ohtsuka, S; Smith, CV; Une, S | 1 |
| Enomoto, N; Ikejima, K; Kolinsky, M; Li, X; Raleigh, JA; Thurman, RG; von Frankenberg, M; Yamashina, S; Zhong, Z | 1 |
| Buttrick, PM; Geenen, DL; Goldspink, PH; Kimball, VA; McKinney, RD | 1 |
| Zhang, W | 1 |
| Demura, M; Mabuchi, H; Takeda, Y; Usukura, M; Yoneda, T | 1 |
| Padgett, EL; Seelig, LL | 1 |
| Butler-Browne, GS; Cooper, RN; Irintchev, A; Wernig, A; Zweyer, M | 1 |
| Deters, M; Kaever, V; Kirchner, G; Klabunde, T; Resch, K | 1 |
| Ahn, HJ; Bang, BK; Cha, JH; Choi, BS; Kim, HW; Kim, J; Kim, WY; Kim, YS; Li, C; Yang, CW | 1 |
| Baker, H; DeAngelis, B; Frank, O; Jyothirmayi, GN; Khalil, M; Leevy, CB; Reddi, AS | 1 |
| Iwasaki, K; Matsuda, H; Murayama, N; Nagata, K; Noda, K; Ozawa, S; Shimada, M; Shiraga, T; Yamazoe, Y; Yasumori, T | 1 |
| Bolton, C | 1 |
| Coyle, P; Haynes, DR; Philcox, JC; Rofe, AM; Whitehouse, MW | 1 |
| Luke, DR | 1 |
| Donatsch, P; Mason, J; Richardson, BP; Ryffel, B | 1 |
| Berlin, J; Epstein, S; Jacobs, T; Joffe, I; Katz, I; Liu, C; Stein, B; Takizawa, M | 1 |
| Berlin, JA; Epstein, S; Fallon, M; Movsowitz, C; Schlosberg, M; Stein, B; Takizawa, M | 1 |
| Dixon, H; Ly, H; McCutcheon, D; Mills, DE; Scholey, J; Ward, RP | 1 |
| Akimoto, R; Endres, D; Kolterman, O; Moossa, AR; Wahlstrom, HE | 1 |
| Hunt, CM; Stave, GM; Westerkam, WR | 1 |
| Adam, BJ; Hasan, NU; Thomson, AW; Whiting, PH; Woo, J | 1 |
| Kawashima, H; Mochizuki, M | 1 |
| Barker, CF; Berezniak, R; Dafoe, DC; Posselt, A; Tafra, L; Wang, X | 1 |
| Bronsther, O; Fung, J; Gordon, RD; Martin, M; Starzl, TE; Stieber, A; Todo, S; Tzakis, AG; Van Thiel, DH | 1 |
| Chen, HF; Daloze, P; Kahan, BD; Stepkowski, SM; Wang, ME | 1 |
| Casse, R; Kabbaj, K; Labat, C; Malmary, MF; Oustrin, J | 1 |
| Bach, M; Brunner, G; Kroeger, T; Lie, TS; Ogawa, K; Preissinger, H; Vogel, J | 1 |
| Davidson, RJ; Duncan, JI; Simpson, JG; Thomson, AW; Whiting, PH | 1 |
1 review(s) available for cyclosporine and Body Weight
| Article | Year |
|---|---|
Old and new tools to dissect calcineurin's role in pressure-overload cardiac hypertrophy.
Topics: A Kinase Anchor Proteins; Adaptor Proteins, Signal Transducing; Adrenergic beta-Agonists; Animals; Animals, Genetically Modified; Body Weight; Calcineurin; Calcineurin Inhibitors; Carrier Proteins; Cyclosporine; DNA-Binding Proteins; Exercise; Gene Transfer Techniques; Hemodynamics; Humans; Hypertension; Hypertrophy, Left Ventricular; Intracellular Signaling Peptides and Proteins; Isoproterenol; Mice; Models, Animal; Muscle Proteins; Myocardium; Phosphoproteins; Rats; Tacrolimus | 2002 |
31 trial(s) available for cyclosporine and Body Weight
| Article | Year |
|---|---|
Multicenter-Based Population Pharmacokinetic Analysis of Ciclosporin in Hematopoietic Stem Cell Transplantation Patients.
Topics: Adolescent; Adult; Aged; Body Weight; Child; Child, Preschool; Cyclosporine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fluconazole; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Immunosuppressive Agents; Itraconazole; Male; Middle Aged; Models, Biological; Reproducibility of Results; Transplantation Conditioning; Voriconazole | 2019 |
Efficacy of cyclosporine for chronic, refractory stomatitis in cats: A randomized, placebo-controlled, double-blinded clinical study.
Topics: Administration, Oral; Animals; Body Weight; Cat Diseases; Cats; Chronic Disease; Cross-Over Studies; Cyclosporine; Dental Prophylaxis; Dental Scaling; Double-Blind Method; Follow-Up Studies; Gingivitis; Immunosuppressive Agents; Placebos; Remission Induction; Stomatitis; Tooth Extraction; Treatment Outcome | 2013 |
Long-term changes in cyclosporine pharmacokinetics after renal transplantation in children: evidence for saturable presystemic metabolism and effect of NR1I2 polymorphism.
Topics: Adolescent; Age Factors; Alleles; Biological Availability; Body Weight; Capsules; Child; Child, Preschool; Cyclosporine; Drug Administration Schedule; Emulsions; Follow-Up Studies; Haplotypes; Humans; Immunosuppressive Agents; Infant; Kidney Transplantation; Models, Biological; Polymorphism, Genetic; Pregnane X Receptor; Receptors, Steroid; Time Factors; Young Adult | 2010 |
Population pharmacokinetics and pharmacogenetics of mycophenolic acid following administration of mycophenolate mofetil in de novo pediatric renal-transplant patients.
Topics: Adolescent; Body Weight; Child; Child, Preschool; Cyclosporine; Female; Genotype; Glucuronosyltransferase; Humans; Immunosuppressive Agents; Infant; Kidney Transplantation; Male; Models, Biological; Multidrug Resistance-Associated Protein 2; Mycophenolic Acid; Nonlinear Dynamics; Pharmacogenetics; Prospective Studies; Tacrolimus; Tissue Distribution | 2010 |
One year evolution of bone mineral density in kidney transplant recipients receiving tacrolimus versus cyclosporine.
Topics: Adult; Body Weight; Bone Density; Cyclosporine; Humans; Immunosuppressive Agents; Kidney Transplantation; Tacrolimus; Time Factors | 2002 |
Body-weight-independent dosing of cyclosporine micro-emulsion and three times weekly maintenance regimen in severe psoriasis. A randomised study.
Topics: Administration, Topical; Adult; Body Surface Area; Body Weight; Cyclosporine; Dermatologic Agents; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Emulsions; Female; Follow-Up Studies; Humans; Male; Middle Aged; Probability; Psoriasis; Quality of Life; Reference Values; Severity of Illness Index; Statistics, Nonparametric; Treatment Outcome | 2002 |
Improved cardiovascular risk profile and renal function in renal transplant patients after randomized conversion from cyclosporine to tacrolimus.
Topics: Adult; Aged; Analysis of Variance; Apolipoproteins B; Blood Glucose; Blood Pressure; Body Weight; Cardiovascular System; Cholesterol; Cyclosporine; Female; Fibrinogen; Fibrinolysis; Graft Survival; Humans; Immunosuppressive Agents; Kidney; Kidney Transplantation; Lipoproteins, LDL; Male; Middle Aged; Oxygen; Risk Factors; Tacrolimus; Time Factors; Triglycerides | 2003 |
Therapeutic drug monitoring of tacrolimus in cardiac transplant recipients: a comparison with cyclosporine neoral.
Topics: Antilymphocyte Serum; Area Under Curve; Biological Availability; Body Weight; Cyclosporine; Drug Monitoring; Female; Heart Transplantation; Humans; Immunosuppressive Agents; Male; Tacrolimus | 2004 |
Cyclosporine A monitoring--how to account for twice and three times daily dosing.
Topics: Adolescent; Area Under Curve; Body Weight; Child; Child, Preschool; Cyclosporine; Drug Monitoring; Graft Rejection; Humans; Immunosuppressive Agents; Infant; Kidney Transplantation; Regression Analysis | 2005 |
Pharmacokinetics of mycophenolic acid in kidney transplant patients receiving sirolimus versus cyclosporine.
Topics: Area Under Curve; Body Weight; Creatinine; Cyclosporine; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Kidney Transplantation; Kinetics; Male; Metabolic Clearance Rate; Middle Aged; Mycophenolic Acid; Sirolimus | 2005 |
Prospective, multicenter, randomized trial to compare incidence of new-onset diabetes mellitus and glucose metabolism in patients receiving cyclosporine microemulsion versus tacrolimus after de novo kidney transplantation.
Topics: Adrenal Cortex Hormones; Adult; Body Weight; Cyclosporine; Diabetes Mellitus; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Mycophenolic Acid; Reoperation; Tacrolimus; Tissue Donors; Treatment Failure; United States; White People | 2005 |
Assessment of converting from intravenous to oral administration of cyclosporin A in pediatric allogeneic hematopoietic stem cell transplant recipients.
Topics: Administration, Oral; Adolescent; Age Factors; Anemia, Aplastic; Biological Availability; Body Weight; Child; Child, Preschool; Cyclosporine; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Infant; Infusions, Intravenous; Leukemia; Male; Metabolic Clearance Rate; Time Factors; Treatment Outcome | 2006 |
Population pharmacokinetics and bayesian estimator of cyclosporine in pediatric renal transplant patients.
Topics: Adolescent; Age Factors; Algorithms; Area Under Curve; Bayes Theorem; Body Weight; Child; Creatinine; Cyclosporine; Female; Humans; Immunosuppressive Agents; Kidney Diseases; Kidney Transplantation; Male; Metabolic Clearance Rate; Models, Biological; Retrospective Studies; Tissue Distribution | 2007 |
Amphotericin B dose optimization in children with malignant diseases.
Topics: Adolescent; Amphotericin B; Antifungal Agents; Body Weight; Child; Child, Preschool; Computer Simulation; Creatinine; Cyclosporine; Deoxycholic Acid; Drug Combinations; gamma-Glutamyltransferase; Humans; Immunosuppressive Agents; Infant; Kidney Diseases; Microbial Sensitivity Tests; Models, Biological; Mycoses; Neoplasms; Risk Factors; Urea | 2007 |
Limitations of cyclosporine C2 monitoring in pediatric heart transplant recipients.
Topics: Adolescent; Body Weight; Child; Child, Preschool; Cyclosporine; Dose-Response Relationship, Drug; Female; Fluorescence Polarization Immunoassay; Follow-Up Studies; Graft Rejection; Heart Transplantation; Humans; Immunosuppressive Agents; Infant; Male; Monitoring, Physiologic; Risk Factors; Treatment Outcome | 2007 |
Is a standard fixed dose of mycophenolate mofetil ideal for all patients?
Topics: Adrenal Cortex Hormones; Asian People; Body Weight; Cyclosporine; Female; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Mycophenolic Acid; Prospective Studies | 2007 |
Treatment with ozone/oxygen-pneumoperitoneum results in complete remission of rabbit squamous cell carcinomas.
Topics: Animals; Anti-Inflammatory Agents; Body Weight; Carcinoma, Squamous Cell; Cyclosporine; Dexamethasone; Head and Neck Neoplasms; Immunosuppressive Agents; Lung Neoplasms; Oxygen; Ozone; Pneumoperitoneum; Rabbits; Remission Induction; Survival Rate | 2008 |
Chronic angiotensin-converting enzyme inhibition may improve sodium excretion in cardiac transplant hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Body Weight; Creatinine; Cross-Over Studies; Cyclosporine; Dopamine; Double-Blind Method; Glomerular Filtration Rate; Heart Transplantation; Humans; Hypertension; Kidney; Lisinopril; Male; Middle Aged; Natriuresis; Nitrendipine | 1995 |
The effect of immunosuppressive drugs on quality of life after renal transplantation.
Topics: Adult; Azathioprine; Body Weight; Cyclosporine; Drug Therapy, Combination; Female; Graft Rejection; Hematologic Tests; Humans; Kidney Transplantation; Male; Middle Aged; Prednisone; Prospective Studies; Quality of Life; Surveys and Questionnaires; Time Factors | 1995 |
Missing impact of cyclosporine on osteoporosis in renal transplant recipients.
Topics: Absorptiometry, Photon; Age Factors; Analysis of Variance; Body Weight; Bone Density; Cyclosporine; Dose-Response Relationship, Drug; Female; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Osteoporosis; Prednisone; Prevalence; Regression Analysis; Sex Factors | 1994 |
Pharmacokinetics of oral cyclosporine in children awaiting renal transplantation.
Topics: Administration, Oral; Body Weight; Child; Cyclosporine; Female; Humans; Kidney Failure, Chronic; Kidney Transplantation; Male; Metabolic Clearance Rate | 1994 |
Steady-state pharmacokinetics of cyclosporine in renal transplant patients: does an influence of age or body weight exist?
Topics: Adolescent; Adult; Age Factors; Body Weight; Child; Child, Preschool; Cyclosporine; Drug Administration Schedule; Humans; Kidney Transplantation; Metabolic Clearance Rate; Middle Aged | 1994 |
Weight-independent dosing of cyclosporine--an alternative to the "mg/kg" doctrine.
Topics: Adolescent; Adult; Aged; Body Weight; Cyclosporine; Female; Humans; Male; Middle Aged; Prospective Studies; Retrospective Studies; Sex Factors; Time Factors | 1994 |
Description of blood pressure changes in patients beginning cyclosporin A therapy.
Topics: Adult; Age Factors; Blood Pressure; Body Weight; Cyclosporine; Female; Humans; Hypertension; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Postoperative Complications; Psoriasis | 1997 |
Effects of pentoxifylline on renal function and blood pressure in cardiac transplant recipients: a randomized trial.
Topics: Adult; Aged; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Body Weight; Cyclosporine; Double-Blind Method; Drug Synergism; Heart Transplantation; Humans; Hypertension; Immunosuppressive Agents; Kidney; Kidney Diseases; Middle Aged; Pentoxifylline; Vasodilator Agents; Weight Gain | 1997 |
Variability in determination of body weight used for dosing busulphan and cyclophosphamide in adult patients: results of an international survey.
Topics: Adult; Body Weight; Bone Marrow Transplantation; Busulfan; Cyclophosphamide; Cyclosporine; Dose-Response Relationship, Drug; Drug Administration Schedule; Graft vs Host Disease; Humans; Immunosuppressive Agents; Methotrexate; Transplantation Conditioning | 1997 |
Pretransplant test-dose pharmacokinetic profiles: cyclosporine microemulsion versus corn oil-based soft gel capsule formulation.
Topics: Administration, Oral; Adult; Aged; Area Under Curve; Biological Availability; Black People; Body Weight; Capsules; Chi-Square Distribution; Cohort Studies; Corn Oil; Cyclosporine; Emulsions; Female; Hispanic or Latino; Humans; Kidney Transplantation; Male; Metabolic Clearance Rate; Middle Aged; Preoperative Care; Time Factors; White People | 1998 |
Late hypertension after liver transplantation: a comparison of cyclosporine and tacrolimus (FK 506).
Topics: Blood Pressure; Body Weight; Cyclosporine; Female; Follow-Up Studies; Glomerular Filtration Rate; Graft Rejection; Humans; Hypertension; Immunosuppressive Agents; Kidney; Liver Transplantation; Male; Middle Aged; Retrospective Studies; Tacrolimus; Vascular Resistance | 1998 |
Effects of nitric oxide blockade and cyclosporin A on cardiovascular and renal function in normal man.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Arachidonic Acid; Blood Pressure; Body Weight; Cardiovascular Physiological Phenomena; Cyclosporine; Dinoprostone; Enzyme Inhibitors; Female; Glomerular Filtration Rate; Humans; Kidney; Male; Nitrates; Nitric Oxide; Nitrites; omega-N-Methylarginine; Reference Values; Renin; Sodium; Thromboxane B2 | 1999 |
A body-weight-independent dosing regimen of cyclosporine microemulsion is effective in severe atopic dermatitis and improves the quality of life.
Topics: Adult; Body Weight; Cyclosporine; Dermatitis, Atopic; Dose-Response Relationship, Drug; Double-Blind Method; Emulsions; Female; Humans; Immunosuppressive Agents; Male; Prospective Studies; Quality of Life | 2000 |
Liver transplantation at the University of Pittsburgh, 1984 to 1990.
Topics: Adolescent; Age Factors; Body Weight; Child; Child, Preschool; Cyclosporine; Graft Survival; Hepatic Encephalopathy; Humans; Immunosuppression Therapy; Infant; Liver Function Tests; Liver Transplantation; Postoperative Complications; Prednisone; Reoperation; Survival Rate; Tacrolimus | 1991 |
237 other study(ies) available for cyclosporine and Body Weight
| Article | Year |
|---|---|
Efficacy and Safety of Early Anti-inflammatory Drug Therapy for Secondary Injury in Traumatic Brain Injury.
Topics: Animals; Body Weight; Brain Injuries, Traumatic; Cyclosporine; Cytokines; Dexamethasone; Disease Models, Animal; Mice; Mice, Inbred C57BL; Neuroinflammatory Diseases | 2023 |
BMI changes and concentration of selected morphological and biochemical indices during cyclosporin A therapy.
Topics: Adult; Body Mass Index; Body Weight; Cyclosporine; Dermatologic Agents; Female; Humans; Immunosuppressive Agents; Male; Middle Aged; Psoriasis | 2019 |
An artificial neural network-pharmacokinetic model and its interpretation using Shapley additive explanations.
Topics: Age Factors; Body Weight; Cyclosporine; Female; Humans; Male; Models, Biological; Neural Networks, Computer; Reproducibility of Results | 2021 |
A Clinical Decision Support Tool to Find the Best Initial Intravenous Cyclosporine Regimen in Pediatric Hematopoietic Stem Cell Transplantation.
Topics: Adolescent; Age Factors; Bayes Theorem; Body Weight; Child; Child, Preschool; Cyclosporine; Decision Support Systems, Clinical; Drug Dosage Calculations; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Infant; Male; ROC Curve; Sex Factors | 2021 |
Cyclosporine in clinical practice: a retrospective study comparing fixed dose and body weight-based dose regimens in psoriatic patients.
Topics: Adult; Aged; Body Weight; Cyclosporine; Dermatologic Agents; Drug Dosage Calculations; Female; Humans; Male; Middle Aged; Psoriasis; Retrospective Studies | 2020 |
Colon-targeted delivery of cyclosporine A using dual-functional Eudragit
Topics: Administration, Oral; Animals; Body Weight; Colitis; Colon; Cyclosporine; Cytokines; Drug Carriers; Drug Delivery Systems; Drug Liberation; Hydrogen-Ion Concentration; Immunosuppressive Agents; Inflammation Mediators; Lactic Acid; Macrophages; Methylmethacrylates; Mice, Inbred ICR; Nanoparticles; Particle Size; Peroxidase; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Treatment Outcome | 2018 |
Oxidative stress-induced renal telomere shortening as a mechanism of cyclosporine-induced nephrotoxicity.
Topics: Aging; Animals; Biomarkers; Body Weight; Creatinine; Cyclosporine; Immunosuppressive Agents; Kidney; Male; Oxidative Stress; Rats, Wistar; Telomerase; Telomere Shortening; Urea | 2018 |
Population pharmacokinetics of cyclosporine in Chinese children receiving hematopoietic stem cell transplantation.
Topics: Adolescent; Antifungal Agents; Asian People; Body Weight; Child; Child, Preschool; Cyclosporine; Cytochrome P-450 CYP3A; Drug Monitoring; Female; Glomerular Filtration Rate; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Infant; Male; Models, Biological; Polymorphism, Genetic; Transplantation, Homologous; Triazoles | 2019 |
Population pharmacokinetics of ciclosporin in Chinese children with aplastic anemia: effects of weight, renal function and stanozolol administration.
Topics: Adolescent; Anemia, Aplastic; Asian People; Body Weight; Child; Child, Preschool; Cyclosporine; Female; Humans; Immunosuppressive Agents; Infant; Kidney Function Tests; Male; Metabolic Clearance Rate; Prospective Studies; Stanozolol | 2013 |
Synergistic protective effects of mizoribine and angiotensin II receptor blockade on cyclosporine A nephropathy in rats.
Topics: Angiotensin Receptor Antagonists; Animals; Body Weight; Cyclosporine; Drug Synergism; Immunosuppressive Agents; Kidney Diseases; Male; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Ribonucleosides | 2014 |
Dose conversion factor between cyclosporine and tacrolimus in pediatric heart transplant recipients.
Topics: Adolescent; Age Factors; Body Weight; Child; Child, Preschool; Cyclosporine; Dose-Response Relationship, Drug; Female; Graft Rejection; Heart Transplantation; Humans; Immunosuppressive Agents; Infant; Male; Mathematical Computing; Retrospective Studies; Tacrolimus; Time Factors | 2014 |
Effects of antioxidant agents against cyclosporine-induced hepatotoxicity.
Topics: Alanine Transaminase; Alkaline Phosphatase; Allopurinol; Animals; Antioxidants; Aspartate Aminotransferases; Bilirubin; Body Weight; Chemical and Drug Induced Liver Injury; Cyclosporine; Drug Evaluation, Preclinical; Liver; Male; Melatonin; Random Allocation; Rats, Sprague-Dawley; Ursodeoxycholic Acid; Xanthine Oxidase | 2015 |
Phosphodiesterase type 5 inhibition attenuates cyclosporine A induced nephrotoxicity in mice.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Body Weight; Cyclosporine; Glyceraldehyde-3-Phosphate Dehydrogenases; Immunohistochemistry; Immunosuppressive Agents; Kidney Diseases; Male; Mice; Organ Size; Oxidative Stress; Phosphodiesterase 5 Inhibitors; Platelet-Derived Growth Factor; Prostaglandin-Endoperoxide Synthases; Transforming Growth Factor beta1; Vardenafil Dihydrochloride | 2015 |
Effect of cyclosporine on liver regeneration in partial hepatectomized rats.
Topics: Animals; Body Weight; Cell Count; Cell Proliferation; Cyclosporine; Disease Models, Animal; Hepatectomy; Immunohistochemistry; Immunosuppressive Agents; Liver Regeneration; Male; Mitotic Index; Proliferating Cell Nuclear Antigen; Random Allocation; Rats, Wistar; Reproducibility of Results; Time Factors; Treatment Outcome | 2015 |
Drug- not carrier-dependent haematological and biochemical changes in a repeated dose study of cyclosporine encapsulated polyester nano- and micro-particles: size does not matter.
Topics: Animals; Body Weight; Cyclosporine; Dose-Response Relationship, Drug; Drug Carriers; Hematopoietic Stem Cells; Male; Microspheres; Nanoparticles; Particle Size; Polyesters; Random Allocation; Rats; Rats, Sprague-Dawley | 2015 |
Anorexia nervosa in a pediatric renal transplant recipient and its reversal with cyclosporine.
Topics: Adolescent; Anorexia Nervosa; Body Weight; Cyclosporine; Female; Graft Survival; Humans; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Transplantation; Tacrolimus; Transplant Recipients; Treatment Outcome | 2015 |
Different preparations, doses, and treatment regimens of cyclosporine A cause adverse effects but no robust changes in seizure thresholds in rats.
Topics: Analysis of Variance; Animals; Behavior, Animal; Body Temperature; Body Weight; Convulsants; Cyclosporine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Electric Stimulation; Female; Immunosuppressive Agents; Kindling, Neurologic; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Time Factors | 2015 |
Population Pharmacokinetic Approach to the Use of Low Dose Cyclosporine in Patients with Connective Tissue Diseases.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Body Weight; Connective Tissue Diseases; Cyclosporine; Female; Humans; Immunosuppressive Agents; Male; Middle Aged; Models, Biological; Nonlinear Dynamics; Young Adult | 2015 |
Protective effect of Epo on oxidative renal injury in rats with cyclosporine nephrotoxicity.
Topics: Animals; Apoptosis; Body Weight; Cyclosporine; Dose-Response Relationship, Drug; Erythropoietin; Female; Hematopoiesis; Humans; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Function Tests; Lipid Peroxidation; Oxidative Stress; Rats; Rats, Wistar; Recombinant Proteins | 2008 |
Determination of initial i.v. CYA dosage to achieve target AUC values in pediatric hematopoietic stem cell transplant patients.
Topics: Administration, Oral; Area Under Curve; Body Surface Area; Body Weight; Child; Cyclosporine; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Injections, Intravenous; Metabolic Clearance Rate; Prospective Studies; Transplantation, Homologous | 2008 |
Pemphigus mouse model as a tool to evaluate various immunosuppressive therapies.
Topics: Animals; Azathioprine; Body Weight; Cyclophosphamide; Cyclosporine; Desmoglein 3; Dexamethasone; Disease Models, Animal; Disease Progression; Female; Immunoglobulin G; Immunosuppressive Agents; Male; Methylprednisolone; Mice; Mice, Inbred C57BL; Mice, Knockout; Pemphigus; Phenotype; Tacrolimus | 2009 |
Red wine polyphenols prevent cyclosporine-induced nephrotoxicity at the level of the intrinsic apoptotic pathway.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blood Pressure; Body Weight; Cyclosporine; Cytochromes c; Flavonoids; Kidney; Kidney Function Tests; Male; Oxidative Stress; Phenols; Polyphenols; Rats; Rats, Wistar; Wine | 2009 |
Effect of mTOR inhibitor on body weight: from an experimental rat model to human transplant patients.
Topics: Adipocytes; Animals; Body Mass Index; Body Weight; Cyclosporine; Disease Models, Animal; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Protein Kinases; Radioimmunoassay; Rats; Rats, Wistar; Sirolimus; TOR Serine-Threonine Kinases; Treatment Outcome | 2008 |
Unusual weight fluctuation under corticosteroid and psychotropic treatment.
Topics: Adult; Anti-Inflammatory Agents; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Appetite; Aripiprazole; Body Weight; Cyclosporine; Depressive Disorder; Drug Interactions; Drug Therapy, Combination; Eating; Female; Humans; Mianserin; Paroxetine; Piperazines; Prednisolone; Quinolones; Sertraline; Takayasu Arteritis | 2008 |
Local inflammation exacerbates cyclosporine a-induced gingival overgrowth in rats.
Topics: Animals; Body Weight; Cyclosporine; Gingiva; Gingival Overgrowth; Gingivitis; Ligation; Male; Molar, Third; Orthodontic Wires; Rats; Rats, Sprague-Dawley; Risk Factors; Transforming Growth Factor beta1 | 2008 |
Metabolic changes following conversion from an anticalcineurin-based therapy to an everolimus-based one: a single-center experience.
Topics: Aged; Blood Pressure; Body Mass Index; Body Weight; Calcineurin Inhibitors; Cyclosporine; Everolimus; Female; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Mycophenolic Acid; Protein Kinases; Retrospective Studies; Sirolimus; TOR Serine-Threonine Kinases | 2008 |
Juvenile toxicity of cyclosporin in the rat.
Topics: Administration, Oral; Animals; Animals, Newborn; Animals, Suckling; Anti-Bacterial Agents; Antibody Formation; Body Weight; Cyclosporine; Female; Heart; Immune System; Kidney; Longevity; Lymph Nodes; Male; Rats; Rats, Sprague-Dawley; Recovery of Function; Sexual Maturation; Spleen; T-Lymphocyte Subsets; Thymus Gland; Tibia; Toxicity Tests; Withholding Treatment | 2009 |
Cyclosporine regulates intestinal epithelial apoptosis via TGF-beta-related signaling.
Topics: Animals; Antibodies; Apoptosis; Body Weight; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspase 8; Colitis; Colon; Cyclosporine; Dextran Sulfate; Disease Models, Animal; Female; Immunosuppressive Agents; Intestinal Mucosa; Mice; Mice, Inbred C57BL; Phosphorylation; Signal Transduction; Smad2 Protein; Time Factors; Transforming Growth Factor beta; Up-Regulation | 2009 |
Protective effects of Mizoribine on Cyclosporine A nephropathy in rats.
Topics: Animals; Anti-Inflammatory Agents; Body Weight; Cyclosporine; Disease Progression; Fibrosis; Immunohistochemistry; Immunosuppressive Agents; Inflammation; Kidney; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Ribonucleosides | 2009 |
Dietary omega-3 fatty acids alter cardiac mitochondrial phospholipid composition and delay Ca2+-induced permeability transition.
Topics: Animals; Body Weight; Calcium; Cardiolipins; Cell Respiration; Cyclosporine; Dietary Fats; Echocardiography; Fatty Acids, Omega-3; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardium; Organ Size; Phospholipids; Rats; Rats, Sprague-Dawley; Superoxides; Ventricular Function, Left | 2009 |
Gene profiling of cyclosporin-enhanced transitional cell carcinoma in rat model.
Topics: Animals; Body Weight; Carcinoma, Transitional Cell; Chromosome Mapping; Cyclosporine; Down-Regulation; Gene Expression Profiling; Gene Expression Regulation; Genetic Variation; Male; Organ Size; Rats; Rats, Sprague-Dawley; Up-Regulation; Urinary Bladder; Weight Gain | 2009 |
Long-term cyclosporine treatment in non-transplanted rats and metabolic risk factors of vascular diseases.
Topics: Animals; Blood Coagulation; Body Weight; Cyclosporine; Fibrinogen; Glucose Tolerance Test; Homocysteine; Humans; Immunosuppressive Agents; Insulin; Leptin; Lipids; Male; Rats; Rats, Wistar; Risk Factors; Vascular Diseases | 2010 |
Explaining variability in ciclosporin exposure in adult kidney transplant recipients.
Topics: Adult; Aged; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Body Weight; Cyclosporine; Cytochrome P-450 CYP3A; Drug Administration Schedule; Female; Fluorescence Polarization Immunoassay; Genotype; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Polymorphism, Genetic; Prednisolone; Pregnane X Receptor; Receptors, Steroid; Survival Analysis | 2010 |
Chronic administration of cyclosporine A changes expression of BDNF and TrkB in rat hippocampus and midbrain.
Topics: Animals; Body Weight; Brain-Derived Neurotrophic Factor; Cell Line, Tumor; Cyclosporine; Down-Regulation; Hippocampus; Humans; Immunosuppressive Agents; Mesencephalon; Rats; Receptor, trkB; RNA, Messenger | 2010 |
Differential effects of acute and sustained cyclosporine and tacrolimus on sympathetic nerve activity.
Topics: Blood Pressure; Body Weight; Calcineurin Inhibitors; Cyclosporine; Dose-Response Relationship, Drug; Heart Rate; Humans; Hypertension; Immunosuppressive Agents; Male; Renin; Sympathetic Nervous System; Tacrolimus | 2010 |
Ameliorative effect of flunarizine in cisplatin-induced acute renal failure via mitochondrial permeability transition pore inactivation in rats.
Topics: Acetylglucosaminidase; Acute Kidney Injury; Adenosine Triphosphate; Animals; Blood Urea Nitrogen; Body Weight; Calcium; Cisplatin; Creatinine; Cyclosporine; Electron Transport Complex IV; Female; Flunarizine; Glutathione; Kidney; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Rats; Rats, Sprague-Dawley; Sodium; Thiobarbituric Acid Reactive Substances | 2011 |
Caffeic acid phenethyl ester protects against oxidative stress-related renal dysfunction in rats treated with cyclosporin A.
Topics: Acute Kidney Injury; Animals; Antioxidants; Blood Urea Nitrogen; Body Weight; Caffeic Acids; Creatinine; Cyclosporine; Disease Models, Animal; Drug Evaluation, Preclinical; Feeding Behavior; Glutathione; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Malondialdehyde; Oxidative Stress; Phenylethyl Alcohol; Rats; Rats, Wistar; Superoxide Dismutase | 2011 |
Reno-protective role of flunarizine (mitochondrial permeability transition pore inactivator) against gentamicin induced nephrotoxicity in rats.
Topics: Animals; Body Weight; Cyclosporine; Flunarizine; Gentamicins; Kidney Diseases; Male; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Rats; Rats, Sprague-Dawley | 2011 |
The effect of low-dose Continuous Erythropoietin receptor activator in an experimental model of acute Cyclosporine A induced renal injury.
Topics: Acute Kidney Injury; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Body Weight; Cell Survival; Cyclosporine; Disease Models, Animal; Dose-Response Relationship, Drug; Erythropoietin; Gene Expression Regulation; Glucose; Hematologic Tests; Interleukin-10; Islets of Langerhans; Kidney; Macrophages; Male; Osteopontin; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1 | 2011 |
Expression of apoptosis-related genes in chronic cyclosporine nephrotoxicity in mice.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Blood Pressure; Body Weight; Caspase 1; Caspase 3; Caspases; Chronic Disease; Cyclosporine; Fas Ligand Protein; fas Receptor; Immunohistochemistry; Immunosuppressive Agents; Kidney Diseases; Male; Membrane Glycoproteins; Mice; Mice, Inbred ICR; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tumor Suppressor Protein p53 | 2002 |
Selective angiotensin II type 1 receptor blockade ameliorates cyclosporine nephrotoxicity.
Topics: Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood Urea Nitrogen; Body Weight; Creatine; Creatinine; Cyclosporine; Drinking; Female; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Function Tests; Lipid Peroxidation; Lipid Peroxides; Male; Oxidative Stress; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Tetrazoles; Urodynamics | 2002 |
Oxidative stress-mediated renal dysfunction by cyclosporine A in rats: attenuation by trimetazidine.
Topics: Animals; Biomarkers; Blood Pressure; Blood Urea Nitrogen; Body Weight; Creatinine; Cyclosporine; Disease Models, Animal; Drinking; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Immunosuppressive Agents; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Oxidative Stress; Rats; Rats, Wistar; Systole; Thiobarbituric Acid Reactive Substances; Time Factors; Treatment Outcome; Trimetazidine; Vasodilator Agents | 2002 |
Cardiovascular risk factors in liver allograft recipients: relationship with immunosuppressive therapy.
Topics: Adolescent; Adult; Aged; Body Weight; Cardiovascular Diseases; Creatinine; Cyclosporine; Diabetes Mellitus; Female; Humans; Hypercholesterolemia; Hypertension; Immunosuppressive Agents; Kidney Function Tests; Liver Transplantation; Male; Middle Aged; Postoperative Complications; Prevalence; Retrospective Studies; Risk Factors; Tacrolimus; Transplantation, Homologous | 2002 |
Cyclosporine does not influence serum cholesterol in kidney transplant recipients.
Topics: Adult; Body Weight; Cholesterol; Creatinine; Cyclosporine; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Retrospective Studies; Time Factors | 2002 |
Mycophenolate mofetil without antibody induction in pediatric renal transplantation.
Topics: Adolescent; Antilymphocyte Serum; Azathioprine; Body Weight; Cadaver; California; Child; Cyclosporine; Drug Therapy, Combination; Female; Humans; Kidney Transplantation; Living Donors; Male; Medical Records; Mycophenolic Acid; Racial Groups; Retrospective Studies; Tacrolimus; Tissue Donors | 2002 |
Actions of immunosuppressor drugs on the development of an experimental ovarian tumor.
Topics: Animals; Body Weight; Cyclosporine; Dexamethasone; Estradiol; Female; Follicle Stimulating Hormone; Immunocompromised Host; Immunosuppressive Agents; Luteinizing Hormone; Luteoma; Neoplasm Transplantation; Organ Size; Ovarian Neoplasms; Ovariectomy; Ovary; Prolactin; Rats; Rats, Sprague-Dawley; Spleen; Thymus Gland; Transplantation, Heterotopic | 2002 |
Gingival eruption cysts induced by cyclosporine administration to neonatal dogs.
Topics: Adenoviridae; Animals; Animals, Newborn; Bicuspid; Body Weight; Cuspid; Cyclosporine; Disease Models, Animal; Dogs; Enamel Organ; Epithelium; Female; Genetic Therapy; Genetic Vectors; Gingival Diseases; Gingivitis; Immunosuppressive Agents; Incisor; Male; Mesoderm; Molar; Muscular Dystrophies; Neutrophils; Odontogenic Cysts; Remission Induction; Tooth Crown; Tooth Eruption | 2002 |
Asymmetric cardiac hypertrophy at autopsy in patients who received FK506 (tacrolimus) or cyclosporine A after liver transplant.
Topics: Adult; Autopsy; Body Weight; Cardiomegaly; Child; Cyclosporine; Female; Humans; Immunosuppressive Agents; Liver Transplantation; Male; Organ Size; Tacrolimus | 2002 |
Salvage of cyclosporine A-induced oxidative stress and renal dysfunction by carvedilol.
Topics: Animals; Antioxidants; Blood Pressure; Body Weight; Carbazoles; Carvedilol; Cyclosporine; Disease Models, Animal; Drinking; Female; Immunosuppressive Agents; Kidney Diseases; Lipid Peroxidation; Male; Oxidative Stress; Propanolamines; Rats; Rats, Wistar; Urine | 2002 |
Two immunotoxicity ring studies according to OECD TG 407-comparison of data on cyclosporin A and hexachlorobenzene.
Topics: Administration, Oral; Animals; Body Weight; Cyclosporine; Drug Evaluation; Evaluation Studies as Topic; Female; Hexachlorobenzene; Immune System; Immunotoxins; Leukocyte Count; Lymph Nodes; Male; Multicenter Studies as Topic; Organ Size; Rats; Rats, Wistar; Spleen; Survival Rate; Thymus Gland; Toxicity Tests, Chronic | 2002 |
The need for continuous immunosuppression with cyclosporin A to maintain an experimental model of uveal melanoma.
Topics: Animals; Body Weight; Cyclosporine; Disease Models, Animal; Humans; Immunosuppressive Agents; Male; Melanoma; Mitosis; Neoplasms, Experimental; Rabbits; Time Factors; Tumor Cells, Cultured; Uvea; Uveal Neoplasms | 2002 |
Diffuse mesenterial sclerosis: a characteristic feature of chronic small-bowel allograft rejection.
Topics: Animals; Blood Vessels; Body Weight; Chronic Disease; Cyclosporine; Disease Models, Animal; Graft Rejection; Immunosuppressive Agents; Intestinal Mucosa; Intestine, Small; Leukocytes, Mononuclear; Male; Mesentery; Rats; Rats, Inbred ACI; Rats, Inbred Lew; Sclerosis; Time Factors; Transplantation, Homologous; Vasculitis | 2003 |
Synergistic effects of mycophenolate mofetil and losartan in a model of chronic cyclosporine nephropathy.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Arterioles; Blood Pressure; Body Weight; Chronic Disease; Cyclosporine; Drug Synergism; Fibrosis; Gene Expression; Immunosuppressive Agents; Kidney; Kidney Diseases; Losartan; Macrophages; Male; Mycophenolic Acid; Osteopontin; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sialoglycoproteins; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2003 |
Cyclosporine a slows the progressive renal disease of alport syndrome (X-linked hereditary nephritis): results from a canine model.
Topics: Animals; Body Weight; Creatinine; Cyclosporine; Disease Models, Animal; Disease Progression; Dogs; Fibrosis; Immunosuppressive Agents; Kidney Concentrating Ability; Kidney Glomerulus; Male; Nephritis, Hereditary; Proteinuria | 2003 |
Nitric oxide production modulates cyclosporin A-induced distal renal tubular acidosis in the rat.
Topics: Acidosis, Renal Tubular; Animals; Arginine; Blood Pressure; Body Weight; Creatine; Cyclosporine; Humans; Immunosuppressive Agents; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Protons; Rats; Rats, Wistar; Renal Circulation | 2003 |
Protein-rich diet attenuates cyclosporin A-induced renal tubular damage in rats.
Topics: Acetylglucosaminidase; Animals; beta-Galactosidase; Body Weight; Caseins; Creatinine; Cyclosporine; Diet, Fat-Restricted; Dietary Proteins; Diuresis; Drinking; Energy Intake; Female; gamma-Glutamyltransferase; Immunohistochemistry; Kidney Diseases; Kidney Tubules, Proximal; Rats; Rats, Sprague-Dawley | 2003 |
Developmental changes in the liver weight- and body weight-normalized clearance of theophylline, phenytoin and cyclosporine in children.
Topics: Administration, Oral; Adolescent; Age Factors; Aryl Hydrocarbon Hydroxylases; Body Surface Area; Body Weight; Child; Child, Preschool; Cyclosporine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Infant; Infant, Newborn; Liver; Metabolic Clearance Rate; Mixed Function Oxygenases; Models, Biological; Organ Size; Phenytoin; Theophylline | 2002 |
Long-term function and morphology of intestinal autografts and allografts in outbred dogs.
Topics: Animals; Body Weight; Cyclosporine; Dogs; Female; Gastrointestinal Transit; Graft Survival; Immunosuppressive Agents; Intestinal Absorption; Intestine, Small; Male; Muscle, Smooth; Time Factors; Transplantation, Autologous; Transplantation, Homologous; Xylose | 2003 |
Simvastatin attenuates renal ischemia/reperfusion injury in rats administered cyclosporine A.
Topics: Analysis of Variance; Animals; Body Weight; Cyclosporine; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Hemodynamics; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunosuppressive Agents; Iohexol; Ischemia; Kidney; Male; Microcirculation; Nitric Oxide; Organ Size; Rats; Rats, Wistar; Reperfusion Injury; Simvastatin; Time Factors; Vasoconstrictor Agents | 2003 |
Phosphodiesterase type 5 inhibition ameliorates nephrotoxicity induced by cyclosporin A in spontaneous hypertensive rats.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Aorta; Benzamides; Blood Platelets; Body Weight; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Cyclosporine; Guanylate Cyclase; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Nitric Oxide Synthase; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Potassium; Rats; Rats, Inbred SHR; Sodium | 2003 |
Hypertrophy of vascularized bone isograft in rats treated with cyclosporine A.
Topics: Amino Acids; Animals; Biomarkers; Body Weight; Bone Density; Bone Transplantation; Cyclosporine; Disease Models, Animal; Fibula; Graft Survival; Hypertrophy; Immunocompromised Host; Immunosuppressive Agents; Male; Osteogenesis; Rats; Rats, Inbred Lew; Tibia; Tomography, X-Ray Computed; Transplantation, Isogeneic | 2003 |
Differential effect of cyclosporine A and SDZ RAD on neointima formation of carotid allografts in apolipoprotein E-deficient mice.
Topics: Animals; Apolipoproteins E; Body Weight; Carotid Arteries; Cholesterol; Cyclosporine; Dose-Response Relationship, Drug; Everolimus; Female; Graft Survival; Immunosuppressive Agents; In Vitro Techniques; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Myocardium; Sirolimus; Transplantation, Homologous; Tunica Intima | 2003 |
Effects of cyclosporin A treatment on the pathogenesis of avian leukosis virus subgroup J infection in broiler chickens with Marek's disease virus exposure.
Topics: Animals; Antibodies, Viral; Avian Leukosis; Avian Leukosis Virus; Body Weight; Chickens; Cyclosporine; Dermatitis, Contact; Flow Cytometry; Immunocompromised Host; Immunohistochemistry; Immunophenotyping; Immunosuppressive Agents; Lymphocyte Activation; Marek Disease; Reverse Transcriptase Polymerase Chain Reaction; RNA, Viral; T-Lymphocytes; Viremia | 2003 |
C2 blood concentrations of orally administered cyclosporine in pediatric liver graft recipients with a body weight below 10 kg.
Topics: Administration, Oral; Antibodies, Monoclonal; Basiliximab; Biliary Atresia; Body Weight; Cyclosporine; Drug Monitoring; Follow-Up Studies; Graft Rejection; Graft Survival; Humans; Immunosuppressive Agents; Infant; Intestinal Absorption; Liver Failure, Acute; Liver Transplantation; Metabolic Diseases; Prednisolone; Prospective Studies; Recombinant Fusion Proteins | 2004 |
Immune and nonimmune predictors of cardiac allograft vasculopathy onset and severity: multivariate risk factor analysis and role of immunosuppression.
Topics: Adult; Age of Onset; Anti-Inflammatory Agents; Body Weight; Coronary Angiography; Coronary Disease; Coronary Vessels; Cyclosporine; Female; Graft Rejection; Heart Transplantation; Humans; Immune Tolerance; Immunosuppression Therapy; Immunosuppressive Agents; Male; Middle Aged; Prednisone; Prognosis; Risk Factors; Transplantation, Homologous | 2004 |
Rapamycin even when combined with cyclosporine attenuates tumor growth but does not induce regression of established walker sarcomas.
Topics: Animals; Body Weight; Cell Division; Cyclosporine; Drug Therapy, Combination; Immunosuppressive Agents; Male; Rats; Rats, Wistar; Sarcoma, Experimental; Sirolimus | 2004 |
Life span extension and reduced neuronal death after weekly intraventricular cyclosporin injections in the G93A transgenic mouse model of amyotrophic lateral sclerosis.
Topics: Age Factors; Amyotrophic Lateral Sclerosis; Animals; Anterior Horn Cells; Body Weight; Cell Survival; Cyclosporine; Disease Models, Animal; Drug Administration Schedule; Hindlimb; Injections, Intraventricular; Longevity; Mice; Mice, Transgenic; Motor Activity; Muscle Weakness; Neuroprotective Agents; Substantia Nigra; Superoxide Dismutase; Time Factors | 2004 |
Short- and long-term results of liver transplantation in infants aged less than 6 months.
Topics: Body Weight; Cyclosporine; Drug Administration Schedule; Female; Follow-Up Studies; Graft Rejection; Humans; Immunosuppressive Agents; Infant; Infant, Newborn; Infections; Liver Diseases; Liver Transplantation; Male; Methylprednisolone; Postoperative Complications; Retrospective Studies; Survival Analysis; Time Factors; Treatment Outcome | 2004 |
Developmental immunotoxicity of cyclosporin-A in rats: age-associated differential effects.
Topics: Animals; Animals, Newborn; Body Weight; Cyclosporine; Cytokines; Female; Fetal Development; Hemocyanins; Hypersensitivity, Delayed; Immunoglobulin G; Immunosuppressive Agents; Leukocyte Count; Litter Size; Nitric Oxide; Organ Size; Pregnancy; Pregnancy Outcome; Random Allocation; Rats; Rats, Sprague-Dawley; Spleen; Thymus Gland | 2005 |
Large cutaneous rabbit papillomas that persist during cyclosporin A treatment can regress spontaneously after cessation of immunosuppression.
Topics: Amino Acid Sequence; Animals; Animals, Inbred Strains; Animals, Outbred Strains; Body Weight; CD4-CD8 Ratio; Cottontail rabbit papillomavirus; Cyclosporine; Disease Models, Animal; Immunocompromised Host; Immunosuppressive Agents; Molecular Sequence Data; Mutation; Neoplasm Regression, Spontaneous; Oncogene Proteins, Viral; Papilloma; Plasmids; Rabbits; Skin Neoplasms; Time Factors | 2005 |
A multidisciplinary evaluation of the effectiveness of cyclosporine a in dystrophic mdx mice.
Topics: Animals; Body Weight; Calcium; Chlorides; Coloring Agents; Creatine Kinase; Cyclosporine; Electrophysiology; Fibrosis; Fura-2; Immunohistochemistry; Immunosuppressive Agents; Ions; Male; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Muscle, Skeletal; Muscles; Muscular Dystrophies; Physical Conditioning, Animal; Spectrophotometry; Time Factors; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2005 |
Effect of mycophenolate mofetil on kidney graft function and body weight in patients with chronic allograft nephropathy.
Topics: Albuminuria; Azathioprine; Body Weight; Creatinine; Cyclosporine; Drug Therapy, Combination; Graft Survival; Humans; Immunosuppressive Agents; Isoantigens; Kidney Transplantation; Mycophenolic Acid; Postoperative Complications; Proteinuria | 2004 |
Efficacy of five human melanocytic cell lines in experimental rabbit choroidal melanoma.
Topics: Animals; Body Weight; Cell Line, Tumor; Choroid Neoplasms; Cyclosporine; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Lung Neoplasms; Male; Melanocytes; Melanoma, Experimental; Penicillin G; Rabbits; Skin Neoplasms; Survival Rate | 2005 |
Expression of tropism-related genes in regenerating skeletal muscle of rats treated with cyclosporin-A.
Topics: Animals; Body Weight; Calpain; Cold Temperature; Cryosurgery; Cyclosporine; Disease Models, Animal; DNA Primers; Enzyme Inhibitors; Gene Expression; Injections, Intraperitoneal; Isoenzymes; Male; Muscle Proteins; Muscle, Skeletal; Myostatin; Rats; Rats, Wistar; Regeneration; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; SKP Cullin F-Box Protein Ligases; Transforming Growth Factor beta | 2005 |
Risk factors for gingival overgrowth in patients medicated with ciclosporin in the absence of calcium channel blockers.
Topics: Anti-Inflammatory Agents; Azathioprine; Body Weight; Creatinine; Cyclosporine; Dental Plaque Index; Female; Gingival Overgrowth; Glucocorticoids; Heart Transplantation; Humans; Immunosuppressive Agents; Kidney Transplantation; Lung Transplantation; Male; Middle Aged; Periodontal Index; Prednisolone; Risk Factors; Time Factors | 2005 |
Influence of cyclosporine on the serum concentration and biliary excretion of mycophenolic acid and 7-O-mycophenolic acid glucuronide.
Topics: Animals; Bile; Bile Acids and Salts; Biliary Fistula; Bilirubin; Body Weight; Cyclosporine; Disease Models, Animal; Drug Administration Schedule; Drug Therapy, Combination; Injections, Intraperitoneal; Male; Mycophenolic Acid; Organ Size; Rats; Rats, Wistar | 2005 |
Cyclosporine A induced changes to plasma and erythrocyte antioxidant defences.
Topics: Animals; Antioxidants; Body Weight; Creatinine; Cyclosporine; Erythrocytes; Female; Malondialdehyde; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2005 |
Correlations between leptin, body composition, bone mineral density, and bone metabolism in kidney transplant recipients.
Topics: Absorptiometry, Photon; Adipose Tissue; Adult; Aged; Body Composition; Body Weight; Bone and Bones; Bone Density; Calcium; Creatinine; Cyclosporine; Humans; Immunosuppressive Agents; Kidney Transplantation; Leptin; Middle Aged; Transplantation, Homologous | 2005 |
Effects of bite-opening and cyclosporin A on the mRNA levels of myosin heavy chain and the muscle mass in rat masseter.
Topics: Animals; Body Weight; Calcineurin Inhibitors; Cyclosporine; Masseter Muscle; Myosin Heavy Chains; Occlusal Splints; Organ Size; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vertical Dimension | 2005 |
Cyclosporine A-induced changes to erythrocyte redox balance is time course-dependent.
Topics: Animals; Antioxidants; Body Weight; Catalase; Cyclosporine; Erythrocytes; Glutathione Peroxidase; Hemoglobins; Immunosuppressive Agents; Lipid Peroxidation; Male; Malondialdehyde; Methemoglobin; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2005 |
mTOR pathway inhibition attenuates skeletal muscle growth induced by stretching.
Topics: Animals; Body Weight; Calcineurin; Calcineurin Inhibitors; Cyclosporine; Gene Expression Regulation; Male; Muscle Proteins; Muscle Stretching Exercises; Muscle, Skeletal; Organ Size; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Wistar; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases | 2006 |
Dietary phytosterols reduce cyclosporine-induced hypercholesterolemia in apolipoprotein E-knockout mice.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Body Weight; Cyclosporine; Diet; Humans; Hypercholesterolemia; Immunosuppressive Agents; Lipids; Male; Mice; Mice, Knockout; Phytosterols; Transplants | 2006 |
Taurine attenuates hypertension and renal dysfunction induced by cyclosporine A in rats.
Topics: Animals; Blood Pressure; Body Weight; Catalase; Cyclosporine; Glutathione; Glutathione Peroxidase; Heart Rate; Hypertension; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Function Tests; Male; Nitric Oxide; Rats; Rats, Wistar; Superoxide Dismutase; Taurine; Thiobarbituric Acid Reactive Substances | 2006 |
The responsiveness of regenerated soleus muscle to pharmacological calcineurin inhibition.
Topics: Animals; Blotting, Western; Body Weight; Calcineurin; Calcineurin Inhibitors; Cyclosporine; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Gene Expression Regulation; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Male; Muscle, Skeletal; Myosin Heavy Chains; Organ Size; Protein Isoforms; Rats; Rats, Wistar; Regeneration; RNA, Messenger; Transcription Factors; Transcription, Genetic | 2006 |
Protective role of polyphenols in cyclosporine A-induced nephrotoxicity during rat pregnancy.
Topics: Animals; Animals, Newborn; Antioxidants; Body Weight; Cyclosporine; Female; Flavonoids; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Glomerulus; Litter Size; Male; Maternal-Fetal Exchange; Matrix Metalloproteinase 2; Morphogenesis; Nitric Oxide Synthase Type II; Phenols; Polyphenols; Pregnancy; Rats; Rats, Wistar | 2006 |
Effects of lactational cyclosporine A use on rat pups.
Topics: Acetylglucosaminidase; Animals; Animals, Newborn; Body Weight; Creatinine; Cyclosporine; Female; Glomerular Filtration Rate; Immunosuppressive Agents; Kidney; Kidney Glomerulus; Kidney Tubules; Lactation; Maternal-Fetal Exchange; Phosphorus; Pregnancy; Prenatal Exposure Delayed Effects; Proteinuria; Random Allocation; Rats; Rats, Wistar; Thymus Gland | 2006 |
Mineralocorticoid receptor blockade confers renoprotection in preexisting chronic cyclosporine nephrotoxicity.
Topics: Animals; Apoptosis; Arterioles; Blood Pressure; Body Weight; Caspase 3; Cell Adhesion Molecules; Cyclosporine; Fibrosis; Immunosuppressive Agents; In Situ Nick-End Labeling; Kidney Diseases; Kidney Glomerulus; Kidney Tubules; Male; Membrane Proteins; Mineralocorticoid Receptor Antagonists; Potassium; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA; Spironolactone; Transforming Growth Factor beta | 2007 |
Developmental immunotoxicity investigations in the SD rat following pre- and post-natal exposure to cyclosporin.
Topics: Animals; Animals, Newborn; Antibody Formation; Autoantibodies; Body Weight; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cyclosporine; Drug Hypersensitivity; Embryonic Development; Erythrocytes; Female; Fetal Mortality; Hypersensitivity, Delayed; Maternal Exposure; Organ Size; Pregnancy; Rats; Rats, Sprague-Dawley; Sheep; Spleen | 2006 |
MDR1 C3435T polymorphisms correlate with cyclosporine levels in de novo renal recipients.
Topics: Adult; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Body Weight; Cyclosporine; Female; Humans; Immunosuppressive Agents; Intestinal Absorption; Kidney Transplantation; Male; Middle Aged; Polymerase Chain Reaction; Polymorphism, Single Nucleotide | 2006 |
FTY720 in combination with cyclosporine--an analysis of skin allograft survival and renal function.
Topics: Animals; Body Weight; Cell Count; Creatinine; Cyclosporine; Drug Therapy, Combination; Fingolimod Hydrochloride; Graft Survival; Histocompatibility Antigens Class II; Immunosuppressive Agents; Intercellular Adhesion Molecule-1; Kidney; Lymph Nodes; Lymphocyte Count; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Potassium; Propylene Glycols; Skin Transplantation; Sodium; Sphingosine; Spleen; Transplantation, Homologous | 2006 |
Pioglitazone limits cyclosporine nephrotoxicity in rats.
Topics: Animals; Arterioles; Blood Pressure; Body Weight; Creatinine; Cyclosporine; Drug Interactions; Gene Expression; Hypoglycemic Agents; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Pioglitazone; Plasminogen Activator Inhibitor 1; Rats; Rats, Wistar; RNA, Messenger; Smad3 Protein; Smad7 Protein; Thiazolidinediones; Transforming Growth Factor beta1 | 2006 |
Dosing time-dependent variation of bone resorption by cyclosporin A in rats' femurs.
Topics: Absorptiometry, Photon; Amino Acids; Animals; Body Weight; Bone Density; Bone Resorption; Calcium; Circadian Rhythm; Creatinine; Cyclosporine; Drug Administration Schedule; Femur; Immunosuppressive Agents; Male; Osteoblasts; Osteocalcin; Osteoclasts; Parathyroid Hormone; Phosphates; Rats; Rats, Wistar | 2007 |
Effects of bisphosphonate treatment on bone repair under immunosuppression using cyclosporine A in adult rats.
Topics: Animals; Biomarkers; Body Weight; Bone Density; Bone Density Conservation Agents; Bone Remodeling; Bone Resorption; Bone Transplantation; Cyclosporine; Diphosphonates; Drug Interactions; Fractures, Bone; Graft Survival; Imidazoles; Immunosuppressive Agents; Male; Osteogenesis; Osteoporosis; Rats; Rats, Inbred Lew; Tibia; Zoledronic Acid | 2007 |
Sulphated polysaccharides: new insight in the prevention of cyclosporine A-induced glomerular injury.
Topics: Animals; Body Weight; Cyclosporine; Hydrolases; Immunosuppressive Agents; Kidney Diseases; Kidney Glomerulus; Male; Polysaccharides; Rats; Rats, Wistar; Sargassum | 2007 |
Overlapping gene expression profiles of model compounds provide opportunities for immunotoxicity screening.
Topics: Acetaminophen; Animals; Benzo(a)pyrene; Body Weight; Cell Cycle; Cyclosporine; Gene Expression Profiling; Gene Expression Regulation; Immune System; Lymph Nodes; Male; Mice; Mice, Inbred C57BL; Spleen; Trialkyltin Compounds | 2008 |
Exhaled nitric oxide concentration in patients after heart transplantation.
Topics: Adult; Body Mass Index; Body Weight; Breath Tests; Cyclosporine; Female; Heart Transplantation; Humans; Immunosuppressive Agents; Luminescence; Male; Nitric Oxide | 2007 |
A comparison of the effects of fish oil and flaxseed oil on cardiac allograft chronic rejection in rats.
Topics: Animals; Blood Pressure; Body Weight; Cholesterol; Chronic Disease; Cyclosporine; Cytokines; Diet; Fish Oils; Graft Rejection; Graft Survival; Heart Rate; Heart Transplantation; Immunosuppressive Agents; Linseed Oil; Lipid Metabolism; Lipids; Lipoproteins; Myocardium; Rats; Rats, Inbred F344; Rats, Inbred Lew | 2008 |
Beneficial effect of shallot (Allium ascalonicum L.) extract on cyclosporine nephrotoxicity in rats.
Topics: Animals; Body Weight; Creatinine; Cyclosporine; Eating; Glutathione; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Function Tests; Male; Malondialdehyde; Plant Extracts; Rats; Rats, Wistar; Shallots; Sodium; Urodynamics | 2008 |
Impaired survival and growth in immunosuppressed young rats with lethal short gut syndrome and a small bowel transplant: an effect of cyclosporine.
Topics: Animal Nutritional Physiological Phenomena; Animals; Body Weight; Cecum; Creatinine; Cyclosporine; Growth; Immunocompromised Host; Intestine, Small; Jejunum; Laparotomy; Male; Rats; Rats, Inbred BN; Rats, Inbred Lew; Serum Albumin; Short Bowel Syndrome; Survival Rate; Transplantation, Homologous; Transplantation, Isogeneic; Triglycerides; Urea | 1995 |
Investigation of a screening battery for immunotoxicity of pharmaceuticals within a 28-day oral toxicity study using azathioprine and cyclosporin A as model compounds.
Topics: Administration, Oral; Animals; Azathioprine; Blood Cell Count; Body Weight; Bone Marrow; Bone Marrow Cells; Cyclosporine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation, Preclinical; Immunoglobulins; Immunosuppressive Agents; Lymphocyte Count; Male; Organ Size; Organ Specificity; Rats; Rats, Wistar; T-Lymphocyte Subsets | 1995 |
The deleterious effects of long-term cyclosporine A, cyclosporine G, and FK506 on bone mineral metabolism in vivo.
Topics: Animals; Body Weight; Bone Resorption; Calcification, Physiologic; Calcitriol; Cyclosporine; Cyclosporins; Female; Immunosuppressive Agents; Male; Osteocalcin; Osteogenesis; Rats; Rats, Sprague-Dawley; Tacrolimus; Tibia; Time Factors | 1994 |
Disruption of mitochondrial calcium homeostasis following chronic doxorubicin administration.
Topics: Analysis of Variance; Animals; Body Weight; Calcium; Cyclosporine; Daunorubicin; Doxorubicin; Homeostasis; Male; Membrane Potentials; Mitochondria, Heart; Mitochondrial Swelling; Organ Size; Oxygen Consumption; Rats; Rats, Inbred F344; Ruthenium Red; Time Factors | 1994 |
Effect of ketanserine in cyclosporine-induced renal dysfunction in rats.
Topics: Animals; Body Weight; Creatinine; Cyclosporine; Female; Immunosuppressive Agents; Ketanserin; Kidney; Prostaglandins; Proteinuria; Rats; Rats, Wistar; Serotonin Antagonists; Thromboxane A2 | 1995 |
Relative importance of ischemic injury and immunological injury on the development of transplant arteriosclerosis in rabbit aortic allografts.
Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Body Weight; Cholesterol; Cyclosporine; Immunosuppressive Agents; Ischemia; Lipoproteins; Male; Rabbits; T-Lymphocytes; Time Factors; Transplantation, Homologous; Tunica Intima | 1995 |
Differences in linear growth and cortisol production between liver and renal transplant recipients on similar immunosuppression.
Topics: Adrenocorticotropic Hormone; Alanine Transaminase; Body Height; Body Weight; Child; Child Development; Child, Preschool; Cyclosporine; Endocrine Glands; Female; Follow-Up Studies; Growth Hormone; Humans; Hydrocortisone; Immunosuppressive Agents; Infant; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Kidney; Kidney Transplantation; Liver; Liver Transplantation; Male | 1995 |
Post-transplant hyperlipidemia: risk factors and response to dietary modification and gemfibrozil therapy.
Topics: Adult; Age Factors; Black People; Blood Glucose; Blood Pressure; Body Weight; Cholesterol; Cholesterol, Dietary; Combined Modality Therapy; Creatinine; Cyclosporine; Diabetes Complications; Diet, Fat-Restricted; Female; Follow-Up Studies; Gemfibrozil; Humans; Hypercholesterolemia; Hypolipidemic Agents; Immunosuppressive Agents; Kidney Transplantation; Male; Patient Compliance; Retrospective Studies; Risk Factors; Serum Albumin; Sex Factors; White People | 1995 |
Quantification of lymphadenopathy in experimentally induced feline immunodeficiency virus infection in domestic cats.
Topics: Animals; Body Weight; Cat Diseases; Cats; Cell Count; Cyclosporine; Feline Acquired Immunodeficiency Syndrome; Female; Hypertrophy; Immunodeficiency Virus, Feline; Lymph Nodes; Lymphatic Diseases; Male; Organ Size; Specific Pathogen-Free Organisms; Zidovudine | 1995 |
Dose study of the immunosuppression of FK 506 in canine lung allo-transplantation.
Topics: Animals; Body Weight; Cyclosporine; Cytotoxicity, Immunologic; Dogs; Dose-Response Relationship, Immunologic; Fibroblasts; Graft Rejection; Immunosuppression Therapy; Leukocytes, Mononuclear; Lung; Lung Transplantation; Models, Biological; Skin; Tacrolimus | 1993 |
Immunosuppressive effect of 15-deoxyspergualin applied to peripheral nerve allotransplantation in the rat.
Topics: Animals; Body Weight; Cyclosporine; Graft Rejection; Guanidines; Immunosuppressive Agents; Peripheral Nerves; Rats; Transplantation, Homologous | 1995 |
Azathioprine alone is bone sparing and does not alter cyclosporin A-induced osteopenia in the rat.
Topics: Animals; Azathioprine; Body Weight; Bone Diseases, Metabolic; Calcitriol; Calcium; Cyclosporine; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Male; Osteocalcin; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Standards; Treatment Outcome | 1995 |
The chemosensitizer cyclosporin A enhances the toxic side-effects of doxorubicin in the rat.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Body Weight; Carrier Proteins; Cyclosporine; Doxorubicin; Drug Resistance; Heart; Kidney; Leukopenia; Male; Membrane Glycoproteins; Rats; Rats, Inbred Strains; Thrombocytopenia | 1994 |
Cyclosporin hypertension in the Wistar rat: role of uninephrectomy.
Topics: Animals; Body Weight; Creatinine; Cyclosporine; Eating; Hypertension; Male; Nephrectomy; Pharmaceutical Vehicles; Placebos; Potassium; Rats; Rats, Wistar; Renin; Sodium | 1994 |
Effects of steroid withdrawal on long-term renal allograft recipients with posttransplantation diabetes mellitus.
Topics: Adrenal Cortex Hormones; Adult; Body Weight; Cholesterol; Cyclosporine; Diabetes Mellitus; Female; Glucose; Humans; Hypertension; Kidney Transplantation; Lipoproteins, HDL; Male; Middle Aged; Prospective Studies; Transplantation, Homologous | 1994 |
Effects of cyclosporin-A and D-penicillamine on the development of hepatitis and the production of antibody to protein disulfide isomerase in LEC rats.
Topics: Administration, Oral; Animals; Autoantibodies; Blood Chemical Analysis; Body Weight; Cyclosporine; Electrophoresis, Polyacrylamide Gel; Female; Hepatitis, Animal; Isomerases; Penicillamine; Protein Disulfide-Isomerases; Radioimmunoassay; Rats; Rats, Mutant Strains; Survival Rate | 1994 |
Cadaveric kidney transplantation in a single centre in Hong Kong.
Topics: Adolescent; Adult; Blood Pressure; Body Weight; Cadaver; Cholesterol; Creatinine; Cyclosporine; Female; Follow-Up Studies; Hemoglobins; Hong Kong; Humans; Kidney Transplantation; Male; Middle Aged; Time Factors; Triglycerides | 1994 |
Interferon-gamma causes loss of bone volume in vivo and fails to ameliorate cyclosporin A-induced osteopenia.
Topics: Animals; Body Weight; Bone and Bones; Bone Diseases, Metabolic; Calcitriol; Calcium; Cyclosporine; Interferon-gamma; Ions; Male; Osteocalcin; Parathyroid Hormone; Rats; Rats, Sprague-Dawley; Reference Values; Tibia | 1994 |
Susceptibility and resistance to cyclosporin A-induced autoimmunity in rats.
Topics: Animals; Autoimmune Diseases; Body Weight; Bone Marrow Transplantation; Cyclosporine; Disease Susceptibility; Female; Graft vs Host Disease; Immunity, Cellular; Immunity, Innate; Immunoenzyme Techniques; Killer Cells, Natural; Langerhans Cells; Rats; Rats, Inbred BN; Rats, Inbred Lew; Thymus Gland | 1993 |
Vascular mechanisms of cyclosporin-induced hypertension in the rat.
Topics: Acetylcholine; Animals; Blood Pressure; Body Weight; Cyclosporine; Dose-Response Relationship, Drug; Drug Interactions; Endothelins; Hypertension; Male; Mesenteric Arteries; Methylene Blue; Muscle Relaxation; Nitroprusside; Norepinephrine; Rats; Rats, Sprague-Dawley; Systole; Vascular Resistance | 1994 |
Cyclosporine-induced nephrotoxicity in the rat. The effect of alpha 1-adrenoceptor blockade with prazosin.
Topics: Animals; Body Weight; Cyclosporine; Kidney; Kidney Transplantation; Male; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Sodium; Sympathetic Nervous System; Urea | 1993 |
Effect of cyclosporine on liver regeneration after orthotopic reduced-size hepatic transplantation in the rat.
Topics: Animals; Body Weight; Bromodeoxyuridine; Cyclosporine; DNA; Hepatectomy; Immunohistochemistry; Liver; Liver Regeneration; Liver Transplantation; Male; Norepinephrine; Organ Size; Rats; Rats, Wistar | 1993 |
Chronic cyclosporin A (CsA) nephrotoxicity in the rat: the effect of calcium blockade with verapamil.
Topics: Animals; Blood Glucose; Body Weight; Cyclosporine; Kidney; Kidney Diseases; Male; Rats; Rats, Sprague-Dawley; Verapamil | 1993 |
Evidence that cyclosporine causes both intracellular migration and inappropriate urinary excretion of magnesium in rats.
Topics: Animals; Body Weight; Bone and Bones; Calcium; Cyclosporine; Kidney; Magnesium; Male; Potassium; Rats; Rats, Sprague-Dawley | 1993 |
The effects of cyclosporin A on transplanted rat allografts.
Topics: Anastomosis, Surgical; Animals; Body Weight; Cyclosporine; Graft Rejection; Graft Survival; Histiocytes; Injections, Intramuscular; Larynx; Lymphocytes; Rats; Rats, Inbred Lew; Rats, Inbred Strains; Salivary Glands, Minor; Transplantation, Homologous | 1993 |
The reversal of experimental cyclosporin A nephrotoxicity by thromboxane synthetase inhibition.
Topics: Animals; Body Weight; Cyclosporine; Enzyme Inhibitors; Kidney Diseases; Male; Prostaglandins; Pyridines; Rats; Rats, Sprague-Dawley; Thromboxane B2; Thromboxane-A Synthase | 1993 |
The effects of cyclosporine in Lewis rats with native and transplanted kidneys.
Topics: Animals; Blood Pressure; Body Weight; Cyclosporine; Inulin; Kidney; Kidney Transplantation; Male; Nephrectomy; Organ Size; p-Aminohippuric Acid; Rats; Rats, Inbred Lew | 1993 |
Body composition and fuel metabolism after kidney grafting.
Topics: Adipose Tissue; Adult; Basal Metabolism; Body Composition; Body Weight; Bone Density; Calorimetry, Indirect; Cyclosporine; Fats; Female; Glucocorticoids; Glucose; Humans; Immunosuppressive Agents; Kidney Transplantation; Longitudinal Studies; Male; Middle Aged; Prednisone; Prospective Studies; Proteins; Sex Characteristics | 1995 |
Endothelium-dependent relaxation in the isolated rat kidney: impairment by cyclosporine A.
Topics: Animals; Arginine; Body Weight; Cholic Acids; Cyclosporine; Endothelium, Vascular; Immunosuppressive Agents; Indomethacin; Kidney; Male; NG-Nitroarginine Methyl Ester; Perfusion; Rats; Rats, Wistar; Vasodilation | 1995 |
Clinically relevant doses and blood levels produce experimental cyclosporine nephrotoxicity when combined with nitric oxide inhibition.
Topics: Animals; Arginine; Body Weight; Cyclosporine; Diet, Sodium-Restricted; Enzyme Inhibitors; Hemodynamics; Kidney Cortex; Kidney Diseases; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley | 1996 |
Effect of Prograf (FK506) on spermatogenesis in rats.
Topics: Animals; Body Weight; Cyclosporine; Epididymis; Female; Fertility; Follicle Stimulating Hormone; Immunosuppressive Agents; Luteinizing Hormone; Male; Organ Size; Prostate; Rats; Reproduction; Seminal Vesicles; Sperm Count; Sperm Motility; Spermatogenesis; Tacrolimus; Testis; Testosterone | 1996 |
Selective suppression of rat hepatic microsomal activity during chronic cyclosporine nephrotoxicity.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Blood Pressure; Body Weight; Cyclosporine; Female; Kidney; Male; Microsomes; Rats; Rats, Sprague-Dawley; Steroid Hydroxylases | 1996 |
Importance of donor/recipient body weight ratio as a cause of kidney graft loss in the short to medium term.
Topics: Adolescent; Adult; Aged; Body Weight; Cyclosporine; Female; Glomerular Filtration Rate; Graft Rejection; Graft Survival; Hemodynamics; Humans; Hypertension; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Organ Size; Proteinuria; Regression Analysis; Retrospective Studies; Tissue Donors | 1996 |
Combined transplantation of small and large bowel. FK506 versus cyclosporine A in a porcine model.
Topics: Animals; Body Weight; Cyclosporine; Endotoxins; Graft Rejection; Graft vs Host Disease; Immunosuppressive Agents; Infections; Intestine, Large; Intestine, Small; Prospective Studies; Swine; Tacrolimus; Toxemia | 1996 |
Role of transforming growth factor-beta 1 in experimental chronic cyclosporine nephropathy.
Topics: Animals; Body Weight; Chronic Disease; Creatinine; Cyclosporine; Disease Models, Animal; Extracellular Matrix Proteins; Fibrosis; Fluorescent Antibody Technique; Gene Expression; Kidney Cortex; Kidney Diseases; Kidney Medulla; Male; Plasminogen Activator Inhibitor 1; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium; Transforming Growth Factor beta | 1996 |
Light microscopic and electron microscopic features of cyclosporine nephrotoxicity in rats.
Topics: Acute Disease; Animals; Body Weight; Chronic Disease; Cyclosporine; Immunosuppressive Agents; Kidney Diseases; Kidney Tubules; Male; Microscopy, Electron; Rats; Rats, Sprague-Dawley | 1995 |
Premedication with cyclosporine and perindopril modifies the ischaemia-reperfusion injury during liver resection in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bilirubin; Body Weight; Cyclosporine; Hepatectomy; Immunosuppressive Agents; Indoles; Liver; Liver Function Tests; Male; Organ Size; Perindopril; Premedication; Prothrombin Time; Rats; Rats, Wistar; Reperfusion Injury | 1996 |
Pharmacokinetics of cyclosporine after renal transplant in children.
Topics: Adolescent; Age Factors; Analysis of Variance; Body Weight; Child; Child, Preschool; Cyclosporine; Female; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Prospective Studies | 1996 |
Effect of dietary supplementation with fish oil on cyclosporine A-induced vascular toxicity.
Topics: Administration, Oral; Animals; Aorta; Blood Pressure; Body Weight; Cyclosporine; Docosahexaenoic Acids; Dose-Response Relationship, Drug; Eicosapentaenoic Acid; Endothelium, Vascular; Fish Oils; Immunosuppressive Agents; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Rats; Rats, Wistar; Serotonin | 1996 |
Magnesium metabolism: basic aspects and implications of ciclosporine toxicity in rats.
Topics: Animals; Aspartic Acid; Body Weight; Calcium; Cyclosporine; Immunohistochemistry; Kidney Function Tests; Kidney Glomerulus; Kidney Tubules; Magnesium; Magnesium Deficiency; Male; Organ Size; Rats; Rats, Sprague-Dawley; Renin | 1996 |
Experimental studies on multiorgan toxicity of cyclosporine-A in rats using a radiopharmaceutical and comparison with histopathological findings.
Topics: Animals; Body Weight; Cyclosporine; Heart; Immunosuppressive Agents; Iodobenzenes; Kidney; Liver; Myocardium; Rats; Rats, Sprague-Dawley; Spleen; Tissue Distribution | 1996 |
Effect of extended sleep deprivation on tumor growth in rats.
Topics: Animals; Body Weight; Carcinoma; Cell Division; Cyclosporine; Eating; Male; Neoplasm Transplantation; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Skin Neoplasms; Sleep Deprivation | 1996 |
Effect of streptozotocin-induced diabetes on cyclosporin A disposition in rats.
Topics: Administration, Oral; Animals; Blood Glucose; Body Weight; Chromatography, High Pressure Liquid; Cyclosporine; Diabetes Mellitus, Experimental; Gastric Emptying; Gastrointestinal Transit; Immunosuppressive Agents; Injections, Intravenous; Intestinal Absorption; Lymphatic System; Male; Rats; Rats, Wistar | 1996 |
Effects of cyclosporine or FK506 in chronic colitis.
Topics: Animals; Blood Pressure; Body Weight; Colitis; Colon; Cyclosporine; Female; Granulomatous Disease, Chronic; Intestinal Mucosa; Liver; Nitrates; Nitrites; Organ Size; Peptidoglycan; Polysaccharides; Rats; Rats, Inbred Lew; Spleen; Tacrolimus | 1997 |
Early elevation of lipoprotein(a) levels in chronic renal insufficiency.
Topics: Adult; Age Distribution; Biomarkers; Body Weight; Creatinine; Cyclosporine; Female; Humans; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Transplantation; Lipoprotein(a); Male; Renal Dialysis; Sex Distribution | 1997 |
Immunotoxicological assessment of cyclosporin A by conventional pathological techniques and immune function testing in the rat.
Topics: Animals; Ataxia; Body Weight; Cyclosporine; Immunologic Tests; Immunosuppressive Agents; Killer Cells, Natural; Lymphocyte Activation; Lymphoid Tissue; Male; Organ Size; Rats; Rats, Wistar; Spleen; Thymus Gland | 1997 |
In vivo effects of leflunomide on normal pancreatic islet and syngeneic islet graft function.
Topics: Animals; Body Weight; Cyclosporine; Immunosuppressive Agents; Islets of Langerhans; Islets of Langerhans Transplantation; Isoxazoles; Leflunomide; Rats; Tacrolimus; Time Factors | 1997 |
The role of the T-lymphocyte in estrogen deficiency osteopenia.
Topics: Animals; Body Weight; Bone Diseases, Metabolic; Cyclosporine; Disease Models, Animal; Estrogens; Female; Osteocalcin; Ovariectomy; Ovary; Rats; Rats, Nude; T-Lymphocytes; Tibia; Vitamin D | 1997 |
The role of testosterone in cyclosporine-induced osteopenia.
Topics: Animals; Blood Urea Nitrogen; Body Weight; Bone Diseases, Metabolic; Calcium; Creatinine; Cyclosporine; Drug Synergism; Humans; Immunosuppressive Agents; Male; Organ Transplantation; Osteocalcin; Osteoporosis; Rats; Rats, Sprague-Dawley; Tacrolimus; Testosterone | 1997 |
Population pharmacokinetics of sirolimus in kidney transplant patients.
Topics: Adult; Aged; Body Surface Area; Body Weight; Cyclosporine; Female; Half-Life; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Middle Aged; Models, Statistical; Polyenes; Sirolimus; Tacrolimus | 1997 |
Modulation of the testicular steroidogenic pathway by cyclosporin A in adult rats pretreated with diethylstilbestrol.
Topics: 17-alpha-Hydroxyprogesterone; Animals; Body Weight; Chorionic Gonadotropin; Cyclosporine; Diethylstilbestrol; Male; Organ Size; Progesterone; Prolactin; Rats; Rats, Inbred F344; Testis; Testosterone | 1997 |
Beneficial effects of pentoxifylline on cyclosporine-induced nephrotoxicity.
Topics: Animals; Blood Pressure; Body Weight; Creatinine; Cyclosporine; Heart Rate; Immunosuppressive Agents; Kidney; Male; Pentoxifylline; Rats; Technetium Tc 99m Pentetate; Vasodilator Agents | 1997 |
Prediction of blood cyclosporine concentrations in haematological patients with multidrug resistance by means of total, lean and different adipose factors dosing body weight using Bayesian and non-linear least squares methods.
Topics: Adult; Bayes Theorem; Bias; Body Weight; Cyclosporine; Drug Resistance, Multiple; Female; Hematologic Diseases; Humans; Immunosuppressive Agents; Least-Squares Analysis; Linear Models; Male; Middle Aged; Sex Factors; Software | 1996 |
Cholesterol feeding accentuates the cyclosporine-induced elevation of renal plasminogen activator inhibitor type 1.
Topics: Animals; Body Weight; Cell Division; Cholesterol, Dietary; Cyclosporine; Immunohistochemistry; Immunosuppressive Agents; Kidney; Lipids; Male; Phenotype; Plasminogen Activator Inhibitor 1; Rats; Rats, Wistar; Staining and Labeling | 1997 |
Effects of cyclosporin A and FK 506 on lipid metabolism and fibrinogen in kidney transplant recipients.
Topics: Adult; Age Factors; Arteriosclerosis; Blood Glucose; Body Weight; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cyclosporine; Fasting; Female; Fibrinogen; Follow-Up Studies; Glucocorticoids; Humans; Immunosuppressive Agents; Kidney Transplantation; Lipid Metabolism; Lipids; Male; Prednisolone; Risk Factors; Sex Factors; Tacrolimus; Transplantation, Homologous; Triglycerides | 1997 |
Alendronate prevents cyclosporin A-induced osteopenia in the rat.
Topics: Administration, Oral; Alendronate; Analysis of Variance; Animals; Body Weight; Bone Diseases, Metabolic; Bone Resorption; Calcitriol; Calcium; Cyclosporine; Disease Models, Animal; Image Processing, Computer-Assisted; Immunosuppressive Agents; Injections, Subcutaneous; Male; Osteocalcin; Osteoclasts; Parathyroid Hormone; Random Allocation; Rats; Rats, Sprague-Dawley; Tibia | 1997 |
Allo- and autotransplantation of carotid artery--a new model of chronic graft vessel disease: evaluation by magnetic resonance imaging and histology.
Topics: Animals; Body Weight; Carotid Arteries; Cyclosporine; Graft vs Host Disease; Magnetic Resonance Imaging; Postmortem Changes; Rats; Rats, Inbred Lew; Rats, Inbred Strains; Transplantation Immunology; Transplantation, Autologous; Transplantation, Homologous | 1997 |
Toxic effect of concomitant administration of cyclosporin A and acyclovir on renal function and morphology in rats.
Topics: Acetylglucosaminidase; Acyclovir; Animals; Antiviral Agents; Blood Urea Nitrogen; Body Weight; Creatinine; Cyclosporine; Drug Combinations; Immunosuppressive Agents; Kidney; Kidney Function Tests; Male; Organ Size; p-Aminohippuric Acid; Proteinuria; Rats; Rats, Wistar | 1997 |
Effect of cyclosporine during initiation of transplant arteriosclerosis. An ultrastructural study in the aorta-transplanted rabbit.
Topics: Animals; Aorta, Abdominal; Aorta, Thoracic; Arteriosclerosis; Body Weight; Cholesterol; Cyclosporine; Endothelium; Graft Rejection; Immunosuppressive Agents; Male; Microscopy; Microscopy, Electron; Microscopy, Electron, Scanning; Pharmaceutical Vehicles; Rabbits; Transplantation, Homologous | 1997 |
Pharmacokinetic cyclosporine A profiles under long-term Neoral treatment in renal transplant recipients: does fat intake still matter?
Topics: Administration, Oral; Body Weight; Cholesterol; Creatinine; Cyclosporine; Diet, Fat-Restricted; Dietary Fats; Female; Hematocrit; Humans; Kidney Transplantation; Male; Metabolic Clearance Rate | 1997 |
Effect of cyclosporin A on the expression of tissue kallikrein, kininogen, and bradykinin receptor in rat.
Topics: Animals; Blood Pressure; Body Weight; Cyclosporine; Gene Expression Regulation; Kallikreins; Kidney; Kininogens; Male; Polymerase Chain Reaction; Rats; Rats, Wistar; Receptors, Bradykinin; Systole | 1997 |
Evolution of cardiovascular risk after liver transplantation: a comparison of cyclosporine A and tacrolimus (FK506).
Topics: Adult; Benzothiadiazines; Blood Glucose; Blood Pressure; Body Weight; Cyclosporine; Diabetes Mellitus; Diuretics; Female; Humans; Hypercholesterolemia; Hypertension; Hypertriglyceridemia; Lipids; Liver Transplantation; Male; Middle Aged; Obesity; Prednisone; Risk Factors; Sex Factors; Sodium Chloride Symporter Inhibitors; Tacrolimus | 1997 |
Gingival overgrowth in pediatric heart and heart-lung transplant recipients.
Topics: Age Factors; Analysis of Variance; Body Weight; Child; Child, Preschool; Cohort Studies; Cyclosporine; Dental Plaque Index; Esthetics, Dental; Female; Follow-Up Studies; Gingival Overgrowth; Gingivitis; Heart Transplantation; Heart-Lung Transplantation; Humans; Immunosuppressive Agents; Incidence; Male; Models, Dental; Oral Hygiene; Periodontal Index; Regression Analysis | 1997 |
Skeletal effects of low-dose cyclosporin A in aged male rats: lack of relationship to serum testosterone levels.
Topics: Aging; Animals; Body Weight; Bone and Bones; Calcification, Physiologic; Cell Count; Cyclosporine; Eating; Injections, Subcutaneous; Linear Models; Male; Osteoclasts; Osteogenesis; Rats; Rats, Wistar; Testosterone | 1998 |
Cyclosporine A nephrotoxicity: role of thromboxane and reactive oxygen species.
Topics: Animals; Body Weight; Cyclosporine; Free Radical Scavengers; Hydrogen Peroxide; Kidney Diseases; Kidney Glomerulus; Lipid Peroxides; Male; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxides; Thromboxane A2; Thromboxane B2; Vitamin E | 1998 |
Regulation of aortic wall structure by the renin-angiotensin system in Wistar rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antirheumatic Agents; Aorta; Body Weight; Cyclosporine; Male; Muscle Contraction; Muscle, Smooth, Vascular; Organ Size; Rats; Rats, Wistar; Receptors, Angiotensin; Renin-Angiotensin System; Tunica Intima; Vasoconstrictor Agents | 1998 |
Cellular adaptations of skeletal muscles to cyclosporine.
Topics: Animals; Body Weight; Cyclosporine; Histocytochemistry; Immunosuppressive Agents; Male; Mitochondria, Muscle; Muscle Fibers, Skeletal; Muscle, Skeletal; Myosin Heavy Chains; Organ Size; Oxidation-Reduction; Rats; Succinate Dehydrogenase | 1998 |
Contribution of individual drugs to gingival overgrowth in adult and juvenile renal transplant patients treated with multiple therapy.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Azathioprine; Body Weight; Calcium Channel Blockers; Child; Child, Preschool; Cyclosporine; Dental Plaque; Drug Combinations; Female; Gingival Overgrowth; Glucocorticoids; Humans; Immunosuppressive Agents; Kidney Transplantation; Lip; Logistic Models; Male; Middle Aged; Mouth Breathing; Nifedipine; Prednisolone; Time Factors | 1998 |
Time-dependent cyclosporine A-induced nephrotoxicity in rats.
Topics: Acetylglucosaminidase; Animals; Body Weight; Creatinine; Cyclosporine; Immunosuppressive Agents; Kidney; Kidney Diseases; Male; Rats; Rats, Wistar; Survival Rate; Time Factors | 1998 |
Effect of misoprostol on myocardial contractility in rats treated with cyclosporin A.
Topics: Animals; Body Weight; Cyclosporine; Female; Gastrointestinal Agents; Heart; Immunosuppressive Agents; In Vitro Techniques; Misoprostol; Myocardial Contraction; Myocardium; Pilot Projects; Rats; Rats, Inbred Lew; Sarcomeres; Strontium | 1998 |
Nephrotoxic serum-induced nephritis in Wistar-Kyoto rats: a model to evaluate antinephritic agents.
Topics: Animals; Basement Membrane; Body Weight; Cyclophosphamide; Cyclosporine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy; Glomerulonephritis; Glucocorticoids; Immunosuppressive Agents; Kidney Glomerulus; Male; Prednisolone; Proteinuria; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Species Specificity; Toxins, Biological; Weight Gain | 1998 |
Effect of colchicine on chronic ciclosporin nephrotoxicity in Sprague-Dawley rats.
Topics: Animals; Body Weight; Colchicine; Cyclosporine; Immunosuppressive Agents; Kidney; Kidney Cortex; Kidney Diseases; Kidney Medulla; Male; Rats; Rats, Sprague-Dawley; Time Factors | 1998 |
Side effects of brequinar and brequinar analogues, in combination with cyclosporine, in the rat.
Topics: Administration, Oral; Animals; Biphenyl Compounds; Blood Cell Count; Body Weight; Bone Marrow; Cyclosporine; Dose-Response Relationship, Drug; Drug Synergism; Immunosuppressive Agents; Jejunum; Leukopenia; Male; Rats; Rats, Inbred Lew; Spleen; Thrombocytopenia; Thymus Gland; Toxicity Tests; Weight Gain | 1998 |
Results of a cyclosporin A ringstudy.
Topics: Animals; Body Weight; Cyclosporine; Evaluation Studies as Topic; Female; Immune System; Immunologic Tests; Immunosuppressive Agents; Male; Organ Size; Rats; Rats, Wistar; Reproducibility of Results; Thymus Gland; Toxicity Tests | 1998 |
Is there a beneficial effect of the calcium channel blocker diltiazem on cyclosporine A nephrotoxicity in rats?
Topics: Animals; Body Weight; Calcium Channel Blockers; Cyclosporine; Cytochrome P-450 Enzyme System; Diltiazem; Drug Interactions; Ethylmorphine; Female; Glomerular Filtration Rate; Glutathione; Immunosuppressive Agents; Kidney; Kidney Diseases; Liver; Organ Size; p-Aminohippuric Acid; Rats; Rats, Wistar | 1998 |
True living donor kidney weight-to-recipient body weight ratio influences posttransplant 1-year renal allograft function.
Topics: Adult; Body Weight; Creatinine; Cyclosporine; Follow-Up Studies; Graft Survival; Humans; Immunosuppressive Agents; Kidney; Kidney Transplantation; Living Donors; Organ Size; Steroids; Time Factors | 1998 |
Mechanism of the diabetogenic action of cyclosporin A.
Topics: Adipocytes; Animals; Biological Transport; Body Weight; Cyclosporine; Epididymis; Glucose; Glucose Intolerance; Glucose Tolerance Test; Immunosuppressive Agents; Insulin; Insulin Resistance; Insulin Secretion; Male; Organ Size; Oxidation-Reduction; Pancreas; Rats; Rats, Wistar | 1998 |
Potentiation of immunosuppressive efficacy by combining the novel leflunomide analog, HMR 279, with microemulsion cyclosporine in a rat lung transplant model.
Topics: Amides; Aniline Compounds; Animals; Biotransformation; Body Weight; Chromatography, High Pressure Liquid; Crotonates; Cyclosporine; Drug Therapy, Combination; Emulsions; Hydroxybutyrates; Immunosuppressive Agents; Isoxazoles; Leflunomide; Lung Transplantation; Male; Nitriles; Rats; Rats, Inbred BN; Rats, Inbred Lew; Structure-Activity Relationship; Toluidines | 1999 |
Modification of release rates of cyclosporin A from polyl(L-lactic acid) microspheres by fatty acid esters and in-vivo evaluation of the microspheres.
Topics: Animals; Arthritis, Experimental; Body Weight; Cyclosporine; Drug Delivery Systems; Fatty Acids; Hindlimb; Immunosuppressive Agents; Lactic Acid; Male; Microspheres; Particle Size; Polyesters; Polymers; Rats; Rats, Wistar | 1999 |
Catecholamine metabolism inhibitors and receptor blockades only partially suppress cardiac hypertrophy of juvenile visceral steatosis mice with systemic carnitine deficiency.
Topics: Adrenergic Antagonists; Animals; Atrial Natriuretic Factor; Body Weight; Cardiomegaly; Carnitine; Cyclosporine; Disease Models, Animal; Mice; Microtubule-Associated Proteins; Muscle Proteins; Norepinephrine; RNA, Messenger | 1999 |
Coadministration of neoral and the novel rapamycin analog, SDZ RAD, to rat lung allograft recipients: potentiation of immunosuppressive efficacy and improvement of tolerability of staggered versus simultaneous treatment.
Topics: Animals; Body Weight; Cyclosporine; Drug Combinations; Everolimus; Immunosuppressive Agents; Lung; Lung Transplantation; Male; Postoperative Care; Radiography, Thoracic; Rats; Rats, Inbred BN; Rats, Inbred Lew; Sirolimus; Transplantation, Homologous | 1999 |
Cyclosporine A-induced alterations in magnesium homeostasis in the rat.
Topics: Animals; Blood Urea Nitrogen; Body Weight; Creatinine; Cyclosporine; Electrolytes; Kidney Cortex; Kidney Tubules, Proximal; Magnesium; Male; Muscle, Skeletal; Rats; Rats, Wistar; Thymus Gland; Water-Electrolyte Balance | 1999 |
Prediction of blood cyclosporine concentrations in non-obese and obese hematologic patients with multidrug resistance using total, lean and different adipose factor dosing body weights.
Topics: Adult; Body Weight; Cyclosporine; Drug Resistance, Multiple; Female; Hematologic Diseases; Humans; Male; Middle Aged; Obesity | 1999 |
Effects of ACE inhibition on cyclosporine A-induced hypertension and nephrotoxicity in spontaneously hypertensive rats on a high-sodium diet.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Body Weight; Creatinine; Cyclosporine; Enalapril; Heart Rate; Hypertension; Hypertrophy, Left Ventricular; Kidney; Potassium; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Sodium, Dietary | 1999 |
Hepatotrophic effect of cyclosporine and FK 506 is not mimicked by rapamycin.
Topics: Animals; Body Weight; Cell Division; Cyclosporine; Hepatectomy; Immunosuppressive Agents; Liver; Liver Regeneration; Male; Rats; Rats, Sprague-Dawley; Sirolimus; Tacrolimus | 1999 |
Augmentative effect of cyclosporin A on rat liver regeneration: influence on hepatocyte growth factor and transforming growth factor-beta(1).
Topics: Animals; Body Weight; Cyclosporine; Hepatectomy; Hepatocyte Growth Factor; Immunosuppressive Agents; Liver; Liver Regeneration; Male; Organ Size; Rats; Rats, Wistar; Reference Values; Transforming Growth Factor beta | 1999 |
Prevention of acute allograft rejection in nonhuman primate lung transplant recipients: induction with chimeric anti-interleukin-2 receptor monoclonal antibody improves the tolerability and potentiates the immunosuppressive activity of a regimen using low
Topics: Animals; Antibodies, Monoclonal; Autopsy; Basiliximab; Biopsy; Body Weight; Bronchoscopy; Creatinine; Cyclosporine; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Emulsions; Everolimus; Graft Rejection; Immune Tolerance; Immunosuppressive Agents; Lung; Lung Transplantation; Macaca fascicularis; Male; Microchemistry; Postoperative Period; Receptors, Interleukin-2; Recombinant Fusion Proteins; Sirolimus; Tissue Donors | 2000 |
Functional, histological, and inflammatory changes in chronically rejecting small bowel transplants.
Topics: Animals; Body Weight; Chronic Disease; Cyclosporine; Graft Rejection; Immunohistochemistry; Immunosuppressive Agents; Inflammation; Intestine, Small; Male; Rats; Rats, Inbred Strains; Serum Albumin; Transplantation, Homologous; Transplantation, Isogeneic | 2000 |
Effects of combined oral treatments with cyclosporine A and nifedipine or diltiazem on drug-induced gingival overgrowth in rats.
Topics: Administration, Oral; Analysis of Variance; Animals; Body Weight; Calcium Channel Blockers; Cyclosporine; Diltiazem; Drug Combinations; Drug Interactions; Gingiva; Gingival Overgrowth; Growth; Immunosuppressive Agents; Male; Nifedipine; Rats; Rats, Inbred F344; Single-Blind Method | 2000 |
Calcineurin Co-regulates contractile and metabolic components of slow muscle phenotype.
Topics: Adenosine Triphosphatases; Animals; Body Weight; Calcineurin; Calcium-Transporting ATPases; Capillaries; Citrate (si)-Synthase; Cyclosporine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Immunohistochemistry; Male; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Myosin Heavy Chains; Phenotype; Protein Isoforms; Rats; Rats, Wistar; Sarcoplasmic Reticulum Calcium-Transporting ATPases | 2000 |
Effect of methyl-prednisone and cyclosporine on the lipid pattern and polyunsaturated fatty acid biosynthesis in the rat.
Topics: Animals; Blood Glucose; Body Weight; Cholesterol; Cyclosporine; Fatty Acids, Unsaturated; Immunosuppressive Agents; Lipids; Male; Microsomes, Liver; Prednisone; Rats; Rats, Wistar; Triglycerides | 1999 |
Enalapril and valsartan improve cyclosporine A-induced vascular dysfunction in spontaneously hypertensive rats.
Topics: Acetylcholine; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Cyclosporine; Dose-Response Relationship, Drug; Enalapril; Hypertension; Male; Mesenteric Arteries; Nitroprusside; Norepinephrine; Rats; Rats, Inbred SHR; Renal Artery; Systole; Tetrazoles; Valine; Valsartan; Vasoconstriction; Vasodilation | 2000 |
Cardiac calcineurin during transition from hypertrophy to heart failure in rats.
Topics: Adaptation, Physiological; Angiotensin-Converting Enzyme Inhibitors; Animals; Blotting, Western; Body Weight; Calcineurin; Calcineurin Inhibitors; Cyclosporine; Disease Progression; Down-Regulation; Electrocardiography; Heart Failure; Hemodynamics; Hypertension; Hypertrophy; Myocardium; Rats; Rats, Inbred Dahl; Thiazepines | 2000 |
Comparison of enalapril and valsartan in cyclosporine A-induced hypertension and nephrotoxicity in spontaneously hypertensive rats on high-sodium diet.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Bradykinin; Bradykinin Receptor Antagonists; Cyclosporine; Dose-Response Relationship, Drug; Drinking; Eating; Electrolytes; Enalapril; Heart Rate; Hypertension; Hypertrophy, Left Ventricular; Kallikreins; Kidney; Kidney Diseases; Male; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; Renin; Sodium, Dietary; Tetrazoles; Urination; Valine; Valsartan | 2000 |
Lesser reduction in bone mineral density by the immunosuppressant, FK506, compared with cyclosporine in rats.
Topics: Amino Acids; Animals; Bile Acids and Salts; Bilirubin; Biomarkers; Body Weight; Bone Density; Cyclosporine; Immunosuppressive Agents; Insulin-Like Growth Factor I; Male; Rats; Rats, Sprague-Dawley; Tacrolimus | 2000 |
Nifedipine prevents changes in nitric oxide synthase mRNA levels induced by cyclosporine.
Topics: Animals; Body Weight; Cyclosporine; Glomerular Filtration Rate; Glyceraldehyde-3-Phosphate Dehydrogenases; Isoenzymes; Kidney Cortex; Kidney Medulla; Liver; Liver Function Tests; Male; Nephrectomy; Nifedipine; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Organ Specificity; Rats; Rats, Wistar; RNA, Messenger | 2000 |
Matching of calcineurin activity to upstream effectors is critical for skeletal muscle fiber growth.
Topics: Adaptation, Physiological; Animals; Blotting, Western; Body Weight; Calcineurin; Calcium Signaling; Calmodulin-Binding Proteins; Cell Count; Cell Size; Cyclosporine; DNA-Binding Proteins; Enzyme Activation; Gene Expression; Genetic Variation; Hypertrophy; MEF2 Transcription Factors; Mice; Mice, Inbred C57BL; Mice, Transgenic; Molecular Weight; Muscle Development; Muscle Fibers, Fast-Twitch; Muscle Fibers, Skeletal; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Myogenic Regulatory Factors; NFATC Transcription Factors; Nuclear Proteins; Organ Size; Phosphorylation; RNA, Messenger; Transcription Factors; Weight-Bearing | 2000 |
Effect of nifedipine in cyclosporine-induced nephrotoxicity in rats: roles of the thromboxane and endothelin systems.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Body Weight; Calcium Channel Blockers; Creatinine; Cyclosporine; Dinoprostone; Dose-Response Relationship, Drug; Endothelin-1; Endothelins; Enzyme Inhibitors; Female; Immunoassay; Kidney; Nifedipine; Proteinuria; Rats; Rats, Wistar; Spectrophotometry; Thromboxane B2; Urine | 2000 |
L-arginine prevents bone loss and bone collagen breakdown in cyclosporin A-treated rats.
Topics: Amino Acids; Animals; Arginine; Body Weight; Bone and Bones; Bone Density; Collagen; Cyclosporine; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley | 2000 |
Uveal melanoma model with metastasis in rabbits: effects of different doses of cyclosporine A.
Topics: Alanine Transaminase; Animals; Blood Urea Nitrogen; Body Weight; Creatinine; Cyclosporine; Follow-Up Studies; Immunosuppression Therapy; Immunosuppressive Agents; Kidney; Lung Neoplasms; Male; Melanoma, Experimental; Rabbits; Survival Rate; Tumor Cells, Cultured; Uveal Neoplasms | 2000 |
Immunosuppressant use without bone loss--implications for bone loss after transplantation.
Topics: Animals; Blood Urea Nitrogen; Body Weight; Bone Density; Bone Diseases, Metabolic; Bone Resorption; Creatinine; Cyclosporine; Dose-Response Relationship, Drug; Drug Synergism; Immunosuppressive Agents; Male; Organ Transplantation; Osteocalcin; Rats; Rats, Sprague-Dawley; Sirolimus; Tibia | 2001 |
Role of soy diet and L-arginine in cyclosporin-A-induced osteopenia in rats.
Topics: Animals; Arginine; Body Weight; Bone Density; Bone Diseases, Metabolic; Calcium; Cyclosporine; Diet; Disease Models, Animal; Drug Therapy, Combination; Immunosuppressive Agents; Injections, Intraperitoneal; Male; Pelvic Bones; Radiography; Rats; Rats, Sprague-Dawley; Soybean Proteins; Spine | 2001 |
The immunomodulatory effects of a novel agent, leflunomide, in rat cardiac allotransplantation.
Topics: Animals; Body Weight; Cyclosporine; Graft Rejection; Graft Survival; Heart Transplantation; Immunosuppressive Agents; Isoxazoles; Leflunomide; Male; Rats; Rats, Inbred Lew; Rats, Inbred Strains; Tacrolimus; Time Factors; Transplantation, Homologous | 1994 |
The endothelin receptor antagonist, L-754,142 does not prevent cyclosporine A-induced osteopenia in rats.
Topics: Acetamides; Administration, Oral; Animals; Blood Urea Nitrogen; Body Weight; Bone Diseases, Metabolic; Calcitriol; Calcium; Creatinine; Cyclosporine; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Immunosuppressive Agents; Male; Osteocalcin; Parathyroid Hormone; Rats; Rats, Sprague-Dawley; Tibia | 2001 |
Combined FTY720/cyclosporine A treatment promotes graft survival and lowers the peripheral lymphocyte count in DA to lewis heart and skin transplantation models.
Topics: Adjuvants, Immunologic; Animals; Body Weight; Cyclosporine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Fingolimod Hydrochloride; Graft Rejection; Graft Survival; Heart Transplantation; Histocompatibility Antigens; Immunosuppressive Agents; Lymphocyte Count; Male; Models, Animal; Propylene Glycols; Rats; Rats, Inbred Lew; Rats, Inbred Strains; Skin Transplantation; Sphingosine | 2001 |
Pharmacokinetic interactions augment toxicities of sirolimus/cyclosporine combinations.
Topics: Animals; Body Weight; Cholesterol; Creatinine; Cyclosporine; Drug Interactions; Glomerular Filtration Rate; Hematopoiesis; Immunosuppressive Agents; Kidney; Male; Rats; Rats, Inbred WF; Sirolimus; Tissue Distribution | 2001 |
RAD reduces compensatory renal graft hypertrophy in a rat model of chronic rejection.
Topics: Animals; Body Weight; Cyclosporine; Disease Models, Animal; Everolimus; Glomerulosclerosis, Focal Segmental; Graft Rejection; Hypertrophy; Immunosuppressive Agents; Kidney Transplantation; Organ Size; Proteinuria; Rats; Rats, Inbred F344; Rats, Inbred Lew; Sirolimus | 2001 |
Effect of low dose cyclosporine and sirolimus on hepatic drug metabolism in the rat1.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Body Weight; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Dose-Response Relationship, Drug; Drug Combinations; Immunosuppressive Agents; Kidney; Liver; Male; Membrane Proteins; Osmolar Concentration; Rats; Rats, Inbred F344; Sirolimus; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases | 2001 |
Beneficial effects of converting liver transplant recipients from cyclosporine to tacrolimus on blood pressure, serum lipids, and weight.
Topics: Blood Pressure; Body Weight; Cyclosporine; Female; Humans; Hyperlipidemias; Hypertension; Immunosuppressive Agents; Lipids; Liver Transplantation; Male; Middle Aged; Retrospective Studies; Risk Factors; Tacrolimus | 2001 |
Sirolimus, but not the structurally related RAD (everolimus), enhances the negative effects of cyclosporine on mitochondrial metabolism in the rat brain.
Topics: Animals; Aspartic Acid; Body Weight; Brain; Cyclosporine; Drug Synergism; Everolimus; gamma-Aminobutyric Acid; Glutamic Acid; Glutamine; Immunosuppressive Agents; Magnetic Resonance Spectroscopy; Mitochondria; Oxaloacetic Acid; Phosphates; Rats; Rats, Wistar; Sirolimus; Weight Gain | 2001 |
Cyclosporin a treatment is able to revert the decrease in circulating GH and IGF-I and the increase in IGFBPs induced by adjuvant arthritis.
Topics: Animals; Arthritis, Experimental; Body Weight; Cyclosporine; Freund's Adjuvant; Growth Hormone; Immunosuppressive Agents; Insulin-Like Growth Factor Binding Protein 1; Insulin-Like Growth Factor Binding Protein 2; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor Binding Protein 4; Insulin-Like Growth Factor Binding Proteins; Insulin-Like Growth Factor I; Male; Rats; Rats, Sprague-Dawley | 2001 |
Quercetin, a bioflavonoid, protects against oxidative stress-related renal dysfunction by cyclosporine in rats.
Topics: Animals; Antioxidants; Blood Pressure; Body Weight; Creatinine; Cyclosporine; Dose-Response Relationship, Drug; Drug Interactions; Female; Flavonoids; Kidney; Kidney Diseases; Kidney Function Tests; Lipid Peroxidation; Male; Oxidative Stress; Quercetin; Rats; Rats, Wistar; Water | 2001 |
Reciprocal regulation of cyclic GMP content by cyclic GMP-phosphodiesterase and guanylate cyclase in SHR with CsA-induced nephrotoxicity.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Body Weight; Cyclic GMP; Cyclosporine; Dose-Response Relationship, Drug; Guanylate Cyclase; Hypertension; Immunosuppressive Agents; In Vitro Techniques; Kidney; Kidney Diseases; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroprusside; Perfusion; Pressure; Rats; Rats, Inbred SHR; Vasodilator Agents | 2001 |
Prolongation of islet allograft survival in mice by combined treatment with pravastatin and low-dose cyclosporine.
Topics: Animals; Blood Glucose; Body Weight; Cyclosporine; Drug Synergism; Graft Survival; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperglycemia; Immunosuppressive Agents; Islets of Langerhans Transplantation; Kidney; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Pravastatin; Transplantation, Homologous | 2001 |
Cyclosporin A causes a hypermetabolic state and hypoxia in the liver: prevention by dietary glycine.
Topics: Animals; Body Weight; Calcium; Chemical and Drug Induced Liver Injury; Cyclosporine; Dietary Supplements; Dinoprostone; Eating; Glycine; Hypoxia; Immunosuppressive Agents; Kupffer Cells; Liver Diseases; Male; Mitochondria, Liver; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Urea | 2001 |
Angiotensin II induced cardiac hypertrophy in vivo is inhibited by cyclosporin A in adult rats.
Topics: Angiotensin II; Animals; Blotting, Northern; Body Weight; Calcineurin; Calcium; Cardiomegaly; Cyclosporine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Hypertrophy; Myocardium; Organ Size; Rats; Rats, Wistar; RNA; Signal Transduction; Up-Regulation | 2001 |
Calcineurin inhibition attenuates mineralocorticoid-induced cardiac hypertrophy.
Topics: Aldosterone; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Atrial Natriuretic Factor; Body Weight; Calcineurin; Calcineurin Inhibitors; Cardiomegaly; Collagen Type III; Cyclosporine; Enzyme Inhibitors; Fibrosis; Heart; Immunosuppressive Agents; Losartan; Male; Mineralocorticoids; Myocardium; Nephrectomy; Organ Size; Rats; Rats, Inbred WKY; RNA, Messenger; Sodium Chloride, Dietary; Tacrolimus | 2002 |
Effects on T-cell maturation and proliferation induced by lactational transfer of cyclosporine to nursing pups.
Topics: Animals; Body Weight; CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cyclosporine; Dose-Response Relationship, Drug; Female; Immunophenotyping; Lactation; Litter Size; Lymphocyte Activation; Models, Animal; Organ Size; Rats; Rats, Inbred F344; T-Lymphocytes | 2002 |
Contractile properties, structure and fiber phenotype of intact and regenerating slow-twitch muscles of mice treated with cyclosporin A.
Topics: Animals; Body Weight; Contractile Proteins; Cyclosporine; Female; Immunohistochemistry; Mice; Mice, Inbred CBA; Muscle Contraction; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Myosin Heavy Chains; Phenotype; Regeneration | 2002 |
Sirolimus/cyclosporine/tacrolimus interactions on bile flow and biliary excretion of immunosuppressants in a subchronic bile fistula rat model.
Topics: Animals; Bile; Bile Acids and Salts; Biliary Fistula; Bilirubin; Body Weight; Cholagogues and Choleretics; Cholesterol; Common Bile Duct Diseases; Cyclosporine; Drug Interactions; Immunosuppressive Agents; Male; Rats; Rats, Wistar; Sirolimus; Tacrolimus; Triglycerides | 2002 |
Cyclosporine withdrawal and mycophenolate mofetil treatment effects on the progression of chronic cyclosporine nephrotoxicity.
Topics: Animals; Apoptosis; Blood Pressure; Body Weight; Cyclosporine; Immunosuppressive Agents; Kidney; Macrophages; Male; Mycophenolic Acid; Osteopontin; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger; Sialoglycoproteins; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2002 |
Effect of cyclosporine treatment on carnitine and myo-inositol in diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Carnitine; Cyclosporine; Diabetes Mellitus, Experimental; Eating; Inositol; Male; Rats; Rats, Inbred Strains | 1992 |
Effect of repeated oral doses of a novel immunosuppressive macrolide lactone on hepatic mixed-function oxidase system in the rat. Comparative study with ciclosporin.
Topics: Animals; Body Weight; Chromatography, High Pressure Liquid; Cyclosporine; Immunosuppressive Agents; In Vitro Techniques; Indicators and Reagents; Liver; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; Organ Size; Proteins; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence; Tacrolimus | 1992 |
The efficacy of cyclosporin A, FK-506 and prednisolone to modify the adoptive transfer of experimental allergic encephalomyelitis (EAE).
Topics: Animals; Body Weight; Cell Division; Cells, Cultured; Cyclosporine; Encephalomyelitis, Autoimmune, Experimental; Immunization, Passive; Leukocyte Transfusion; Leukocytes; Male; Myelin Basic Protein; Prednisolone; Rats; Rats, Inbred Lew; Spleen; Tacrolimus | 1992 |
Changes in plasma zinc, copper, iron, and hepatic metallothionein in adjuvant-induced arthritis treated with cyclosporin.
Topics: Animals; Arthritis, Experimental; Body Weight; Copper; Cyclosporine; Eating; Interleukin-6; Iron; Liver; Macrophages; Male; Metallothionein; Peritoneal Cavity; Rats; Trace Elements; Tumor Necrosis Factor-alpha; Zinc | 1992 |
Immunosuppressive effect of cyclosporine in the hyperlipidemic rat model.
Topics: Animals; Body Weight; Cell Division; Cyclosporine; Female; Hyperlipidemias; Immunosuppressive Agents; Lipoproteins; Obesity; Organ Size; Rats; Rats, Zucker; T-Lymphocytes | 1992 |
Toxicologic evaluation of the new cyclosporin derivative, SDZ IMM 125, in a comparative, subchronic toxicity study in rats.
Topics: Alkaline Phosphatase; Animals; Biological Availability; Blood Chemical Analysis; Body Weight; Cyclosporine; Cyclosporins; Death; Drinking; Eating; Immunosuppressive Agents; Kidney; Liver; Male; Organ Size; Rats; Rats, Inbred Strains; Thymus Gland; Transaminases | 1992 |
17 beta-estradiol prevents osteopenia in the oophorectomized rat treated with cyclosporin-A.
Topics: Animals; Body Weight; Bone Development; Bone Diseases, Metabolic; Bone Resorption; Calcium; Cyclosporine; Estradiol; Female; Osteocalcin; Ovariectomy; Parathyroid Hormone; Rats; Rats, Inbred Strains | 1992 |
Evidence that cyclosporine G is less deleterious to rat bone in vivo than cyclosporine A.
Topics: Animals; Body Weight; Bone and Bones; Bone Density; Calcitriol; Calcium; Cyclosporine; Cyclosporins; Immunosuppressive Agents; Male; Minerals; Osteocalcin; Parathyroid Hormone; Rats; Rats, Inbred Strains; Tibia | 1992 |
Attenuation of cyclosporine-induced hypertension by dietary fatty acids in the borderline hypertensive rat.
Topics: Animals; Blood Pressure; Body Weight; Cyclosporine; Dietary Fats, Unsaturated; Glomerular Filtration Rate; Hypertension; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Regional Blood Flow; Renal Circulation | 1992 |
Recovery and hypersecretion of insulin and reversal of insulin resistance after withdrawal of short-term cyclosporine treatment.
Topics: Animals; Body Weight; Cyclosporine; Dogs; Dose-Response Relationship, Drug; Glucagon; Glucose Clamp Technique; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Male | 1992 |
Effect of age and gender on the activity of human hepatic CYP3A.
Topics: Adult; Aged; Aged, 80 and over; Aging; Alcohol Drinking; Aryl Hydrocarbon Hydroxylases; Body Weight; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Diltiazem; Humans; Lidocaine; Microsomes, Liver; Middle Aged; Nifedipine; Oxidoreductases, N-Demethylating; Quinidine; Sex Factors; Smoking | 1992 |
The effect of rapamycin on renal function in the rat: a comparative study with cyclosporine.
Topics: Acetylglucosaminidase; Animals; Blood Glucose; Body Weight; Cyclosporine; gamma-Glutamyltransferase; Glycosuria; Immunosuppressive Agents; Kidney; Male; Polyenes; Rats; Rats, Inbred Strains; Sirolimus | 1991 |
Effects of FK506, 15-deoxyspergualin, and cyclosporine on experimental autoimmune uveoretinitis in the rat.
Topics: Animals; Antibodies; Antigens; Arrestin; Autoimmune Diseases; Body Weight; Cyclosporine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation, Preclinical; Enzyme-Linked Immunosorbent Assay; Eye; Eye Proteins; Guanidines; Immunosuppressive Agents; Male; Rats; Rats, Inbred Lew; Tacrolimus; Uveitis | 1990 |
Intraportal FK 506 improves intrahepatic islet allograft survival.
Topics: Animals; Body Weight; Budesonide; Cyclosporine; Diabetes Mellitus, Experimental; Glucocorticoids; Graft Survival; Injections, Intravenous; Islets of Langerhans Transplantation; Portal Vein; Pregnenediones; Rats; Rats, Inbred Lew; Rats, Inbred WF; Tacrolimus; Transplantation, Homologous | 1991 |
Inhibition of host-versus-graft and graft-versus-host responses after small bowel transplantation in rats by rapamycin.
Topics: Animals; Body Weight; Cyclosporine; Dose-Response Relationship, Drug; Graft Survival; Graft vs Host Reaction; Host vs Graft Reaction; Immunosuppressive Agents; Intestinal Absorption; Intestine, Small; Male; Maltose; Polyenes; Rats; Rats, Inbred BN; Rats, Inbred BUF; Rats, Inbred Lew; Rats, Inbred WF; Sirolimus; Transplantation, Homologous | 1992 |
Cyclosporine A dosing-time-dependent effects on plasma creatinine and body weight in male Wistar rats treated for 3 weeks.
Topics: Administration, Oral; Analysis of Variance; Animals; Body Weight; Circadian Rhythm; Creatinine; Cyclosporine; Darkness; Drug Administration Schedule; Kidney; Light; Male; Rats; Rats, Inbred Strains; Reference Values | 1991 |
The protective effect of cyclosporine against cirrhotic alteration of the liver.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bilirubin; Body Weight; Carbon Tetrachloride Poisoning; Collagen; Cyclosporine; Liver; Liver Cirrhosis, Experimental; Male; Rats; Rats, Inbred Strains | 1991 |
A comparative toxicological study of cyclosporine and Nva2-cyclosporine in Sprague-Dawley rats.
Topics: Animals; Antibody Formation; Body Weight; Cyclosporine; Cyclosporins; Hematopoietic System; Kidney; Liver; Male; Rats; Rats, Inbred Strains | 1986 |