cyclosporine and Becker Muscular Dystrophy

cyclosporine has been researched along with Becker Muscular Dystrophy in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (37.50)29.6817
2010's8 (50.00)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Belosludtsev, KN; Belosludtseva, NV; Dubinin, MV; Mikheeva, IB; Starinets, VS; Talanov, EY1
Belosludtsev, KN; Dubinin, MV; Mikheeva, IB; Starinets, VS1
Argenton, F; Bernardi, P; Menazza, S; Merlini, L; Petronilli, V; Sabatelli, P; Schiavone, M; Zulian, A1
Becker, TS; Berger, J; Brouilly, N; Currie, PD; Giacomotto, J; Gieseler, K; Mariol, MC; Ségalat, L; Walter, L1
Janíček, R; Kyrychenko, V; Poláková, E; Shirokova, N1
Babarit, C; Dubreil, L; Goubin, H; Guével, L; Larcher, T; Ledevin, M; Robriquet, F; Rouger, K1
Dorchies, OM; Patthey-Vuadens, O; Reutenauer, J; Ruegg, UT; Vuagniaux, G1
Bernert, G; Grieben, U; Hobbiebrunken, E; Ihorst, G; Kirschner, J; Korinthenberg, R; Lütschg, J; Müller-Felber, W; Reitter, B; Schara, U; Schessl, J; Schmoor, C; Stehling, F; Stettner, GM; Thiele, S; von der Hagen, M; Weiss, S; Wiegand, G; Wilichowski, E1
Griggs, RC1
Duan, D; Lai, Y; Shin, JH; Smith, B; Srivastava, A; Yue, Y1
Barthélémy, I; Blot, S; Drougard, C; Thibaud, JL; Unterfinger, Y; Uriarte, A1
Andreetta, F; Cerletti, M; Colpo, R; Cornelio, F; Cozzi, F; Croci, D; Davies, KE; Gilbert, R; Karpati, G; Mora, M; Negri, T; Pozza, O1
Gregorevic, P; Lynch, GS; Plant, DR; Stupka, N1
Chen, C; Chen, W; Fang, JP; Feng, HY; Feng, SW; Huang, K; Huang, SL; Li, Y; Li, Z; Liu, Y; Lu, XL; Wen, JM; Xi, J; Xiao, LL; Xie, YM; Xu, HG; Yao, XL; Ye, X; Zeng, Y; Zhang, C; Zhang, M; Zhang, WX; Zhou, DH1
Allen, JM; Blankinship, M; Chamberlain, JS; Gregorevic, P; Kuhr, CS; Storb, R; Tapscott, SJ; Wang, Z1
Hijikata, T; Howell, JM; Miyagoe-Suzuki, Y; Nakamura, A; Ohshima, S; Takeda, S; Urasawa, N; Yoshimura, M; Yuasa, K1

Trials

1 trial(s) available for cyclosporine and Becker Muscular Dystrophy

ArticleYear
Treatment of Duchenne muscular dystrophy with ciclosporin A: a randomised, double-blind, placebo-controlled multicentre trial.
    The Lancet. Neurology, 2010, Volume: 9, Issue:11

    Topics: Child; Cyclosporine; Double-Blind Method; Humans; Male; Muscular Dystrophy, Duchenne; Review Literature as Topic; Treatment Outcome

2010

Other Studies

15 other study(ies) available for cyclosporine and Becker Muscular Dystrophy

ArticleYear
Alisporivir Improves Mitochondrial Function in Skeletal Muscle of
    International journal of molecular sciences, 2021, Sep-10, Volume: 22, Issue:18

    Topics: Animals; Cyclophilins; Cyclosporine; Dynamins; Dystrophin; Gene Expression Regulation; GTP Phosphohydrolases; Humans; Mice; Mice, Inbred mdx; Mitochondria; Mitochondria, Muscle; Mitochondrial Dynamics; Mitochondrial Permeability Transition Pore; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha

2021
Effect of Alisporivir on Calcium Ion Transport and Mitophagy in Skeletal Muscle and Heart Mitochondria in Dystrophin-Deficient Mice.
    Bulletin of experimental biology and medicine, 2022, Volume: 172, Issue:6

    Topics: Animals; Calcium; Cyclosporine; Dystrophin; Ion Transport; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Mitochondria, Heart; Mitophagy; Muscle, Skeletal; Muscular Dystrophy, Duchenne

2022
Alisporivir rescues defective mitochondrial respiration in Duchenne muscular dystrophy.
    Pharmacological research, 2017, Volume: 125, Issue:Pt B

    Topics: Animals; Cell Respiration; Cells, Cultured; Cyclosporine; Disease Models, Animal; Humans; Membrane Potential, Mitochondrial; Mitochondria; Muscle Cells; Muscular Dystrophy, Animal; Muscular Dystrophy, Duchenne; Oxygen Consumption; Zebrafish

2017
Chemical genetics unveils a key role of mitochondrial dynamics, cytochrome c release and IP3R activity in muscular dystrophy.
    Human molecular genetics, 2013, Nov-15, Volume: 22, Issue:22

    Topics: Animals; Animals, Genetically Modified; Binding Sites; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cell Death; Cyclophilins; Cyclosporine; Cytochromes c; Gene Knockdown Techniques; Humans; Inositol 1,4,5-Trisphosphate Receptors; Methazolamide; Mitochondrial Dynamics; Mitochondrial Proteins; Muscular Dystrophy, Animal; Muscular Dystrophy, Duchenne; Phylogeny; Sequence Homology; Zebrafish

2013
Mitochondrial dysfunctions during progression of dystrophic cardiomyopathy.
    Cell calcium, 2015, Volume: 58, Issue:2

    Topics: Animals; Calcium; Cells, Cultured; Cyclosporine; Cytosol; Disease Models, Animal; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Muscular Dystrophy, Duchenne; Myocytes, Cardiac; NAD; Oxidative Stress; Sodium

2015
Identification in GRMD dog muscle of critical miRNAs involved in pathophysiology and effects associated with MuStem cell transplantation.
    BMC musculoskeletal disorders, 2016, 05-11, Volume: 17

    Topics: Animals; Biomarkers; Cyclosporine; Disease Models, Animal; Dogs; Down-Regulation; Fluorescent Antibody Technique; Humans; Immunosuppression Therapy; Immunosuppressive Agents; In Situ Hybridization; Injections, Intra-Arterial; Mice; Mice, Inbred mdx; MicroRNAs; Muscle Cells; Muscle, Skeletal; Muscular Dystrophy, Animal; Muscular Dystrophy, Duchenne; Myosin Heavy Chains; Stem Cell Transplantation; Stem Cells; Up-Regulation

2016
Investigation of Debio 025, a cyclophilin inhibitor, in the dystrophic mdx mouse, a model for Duchenne muscular dystrophy.
    British journal of pharmacology, 2008, Volume: 155, Issue:4

    Topics: Animals; Animals, Newborn; Cell Death; Cyclophilins; Cyclosporine; Diaphragm; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Delivery Systems; Female; Hindlimb; Male; Mice; Mice, Inbred mdx; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Muscle, Skeletal; Muscular Dystrophy, Animal; Muscular Dystrophy, Duchenne; Necrosis

2008
Duchenne muscular dystrophy: an important negative trial.
    The Lancet. Neurology, 2010, Volume: 9, Issue:11

    Topics: Cyclosporine; Humans; Multicenter Studies as Topic; Muscular Dystrophy, Duchenne; Randomized Controlled Trials as Topic

2010
A simplified immune suppression scheme leads to persistent micro-dystrophin expression in Duchenne muscular dystrophy dogs.
    Human gene therapy, 2012, Volume: 23, Issue:2

    Topics: Animals; Antilymphocyte Serum; Cyclosporine; Dependovirus; Disease Models, Animal; Dogs; Dystrophin; Female; Gene Expression; Genetic Therapy; Genetic Vectors; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Injections, Intramuscular; Male; Mice; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Mycophenolic Acid; T-Lymphocytes; Transgenes

2012
Effects of an immunosuppressive treatment in the GRMD dog model of Duchenne muscular dystrophy.
    PloS one, 2012, Volume: 7, Issue:11

    Topics: Accelerometry; Animals; Biomechanical Phenomena; Creatine Kinase; Cyclosporine; Disease Models, Animal; Dogs; Follow-Up Studies; Gait; Humans; Immunosuppressive Agents; Motor Activity; Muscular Dystrophy, Animal; Muscular Dystrophy, Duchenne; Principal Component Analysis; Tetany

2012
Dystrophic phenotype of canine X-linked muscular dystrophy is mitigated by adenovirus-mediated utrophin gene transfer.
    Gene therapy, 2003, Volume: 10, Issue:9

    Topics: Adenoviridae; Animals; CD4 Lymphocyte Count; Cyclosporine; Cytoskeletal Proteins; Dog Diseases; Dogs; Dystrophin; Female; Fibrosis; Gene Expression; Genetic Therapy; Genetic Vectors; Immunohistochemistry; Immunosuppressive Agents; Male; Membrane Proteins; Models, Animal; Muscle, Skeletal; Muscular Dystrophy, Animal; Muscular Dystrophy, Duchenne; Transduction, Genetic; Transgenes; Utrophin

2003
The calcineurin signal transduction pathway is essential for successful muscle regeneration in mdx dystrophic mice.
    Acta neuropathologica, 2004, Volume: 107, Issue:4

    Topics: Animals; Animals, Newborn; Blotting, Western; Calcineurin; Cyclosporine; Disease Models, Animal; Enzyme Inhibitors; Immunohistochemistry; Isometric Contraction; Male; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Muscle Fatigue; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Organ Size; Regeneration; Signal Transduction

2004
[Therapy of Duchenne muscular dystrophy with umbilical cord blood stem cell transplantation].
    Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, 2005, Volume: 22, Issue:4

    Topics: Alprostadil; Busulfan; Child; Combined Modality Therapy; Cord Blood Stem Cell Transplantation; Cyclosporine; Dystrophin; Ganciclovir; Humans; Male; Methylprednisolone; Muscular Dystrophy, Duchenne; Polymerase Chain Reaction; Treatment Outcome

2005
Sustained AAV-mediated dystrophin expression in a canine model of Duchenne muscular dystrophy with a brief course of immunosuppression.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2007, Volume: 15, Issue:6

    Topics: Animals; Antilymphocyte Serum; Cyclosporine; Dependovirus; Dogs; Drug Therapy, Combination; Dystrophin; Flow Cytometry; Gene Expression; Genetic Therapy; Genetic Vectors; Immunosuppression Therapy; Immunosuppressive Agents; Muscle, Skeletal; Muscular Dystrophy, Animal; Muscular Dystrophy, Duchenne; Mycophenolic Acid

2007
Injection of a recombinant AAV serotype 2 into canine skeletal muscles evokes strong immune responses against transgene products.
    Gene therapy, 2007, Volume: 14, Issue:17

    Topics: Animals; Base Sequence; beta-Galactosidase; Calmodulin; Cyclosporine; Dependovirus; Dogs; Dystrophin; Genetic Engineering; Genetic Therapy; Genetic Vectors; Immunosuppressive Agents; Injections, Intramuscular; Interferon-gamma; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Models, Animal; Molecular Sequence Data; Muscle Fibers, Skeletal; Muscle, Skeletal; Muscular Dystrophy, Animal; Muscular Dystrophy, Duchenne; Parvoviridae Infections; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Species Specificity; T-Lymphocytes, Cytotoxic; Transduction, Genetic; Transgenes

2007