cyclosporine has been researched along with Anemia, Aplastic in 583 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 130 (22.30) | 18.2507 |
| 2000's | 177 (30.36) | 29.6817 |
| 2010's | 203 (34.82) | 24.3611 |
| 2020's | 73 (12.52) | 2.80 |
| Authors | Studies |
|---|---|
| Usuki, K | 1 |
| Groarke, EM; Gutierrez-Rodrigues, F; Lotter, J; Patel, BA; Quinones Raffo, D; Rios, O; Shalhoub, R; Wu, CO; Young, NS | 1 |
| Hayashida, H; Hino, T; Honda, A; Kurokawa, M; Mizuno, H; Toyama, K | 1 |
| Angelucci, E; Barcellini, W; Barraco, F; Cacace, F; Cavenagh, J; Clement, L; Cook, R; Daguindau, E; de Groot, MR; Drexler, B; Dufour, C; Forcade, E; Frieri, C; Griffin, M; Halkes, CJM; Hill, A; Iacobelli, S; Iori, AP; Jarque, I; Kulasekararaj, A; La Rocca, U; Marano, L; Marotta, S; Marsh, JCW; Mear, JB; Mufti, GJ; Munir, T; Muus, P; Nur, E; Palmisani, E; Passweg, JR; Peffault de Latour, R; Praire, A; Rabian, F; Raymakers, RAP; Recher, C; Risitano, AM; Russell, NH; Sánchez-Ortega, I; Sicre de Fontbrune, F; Smith, AE; Socié, G; Sureda, A; Tavitian, S; Terriou, L; Terwel, SR; Tjon, JML; Vallejo, JC; van Lint, MT; Xicoy, B | 1 |
| Jiao, DL; Li, WJ; Qi, L; Shi, JF; Zhao, C | 1 |
| Chen, HB; Jin, RM; Qiu, YN; Shen, YQ; Wang, ZJ; Wu, XY; Yu, H; Zhou, F | 1 |
| Chen, Y; Huang, F; Li, JY; Qiao, C; Shen, WY; Wang, R; Wang, Y; Zha, Q | 1 |
| Chen, X; He, SM; Mao, YZ; Wang, DD; Yang, Y; Yin, D; Zheng, ZQ | 1 |
| Chan, FHY; Chan, KP; Chan, TSY; Hwang, YY; Kho, B; Kwong, YL; Lau, CK; Lau, CWP; Lau, GWN; Lau, JSM; Leung, KH; Lin, SY; Luk, YY; Mak, V; Sim, JPY; Yip, SF | 1 |
| Ding, S; Fu, R | 1 |
| Chen, M; Du, Y; Han, B; Ruan, J; Yang, C | 1 |
| Hosokawa, K; Ishiyama, K; Katagiri, T; Kishi, H; Nakao, S; Ogawa, S; Ozawa, T; Takamatsu, H; Tanabe, M; Tsuji, N; Urushihara, R; Yamazaki, H; Zaimoku, Y | 1 |
| Jie, G; Ma, J; Teng, Q; Wang, L; Wang, S; Wu, Q; Zhang, F; Zhang, H; Zhang, L; Zhao, C; Zhou, F | 1 |
| Han, J; Ren, R | 1 |
| Cao, J; Chen, W; Cheng, H; Qi, N; Wang, X; Xu, KL; Zhang, XT; Zhang, YN; Zhu, JJ | 1 |
| Honda, A; Kurokawa, M; Masamoto, Y; Matsuda, K; Murakami, D | 1 |
| He, G; Jia, J; Jin, Y; Li, J; Li, R; Lin, S; Yang, Y; Zhang, D | 1 |
| Gonnot, M; Huet, F; Lacaille, F; Leblanc, T; Maudinas, R; Neumann, F | 1 |
| Boswell, KL; Carroll, R; Darden, I; Gaudinski, M; Gordon, I; Groarke, EM; Jean-Baptiste, N; Koup, RA; Lin, BC; Lotter, J; Ma, X; McDermott, A; Moore, C; Naisan, M; Narpala, SR; Novik, L; Patel, BA; Prabhakaran, M; Rajput, RV; Rios, OJ; Serebryannyy, L; Superata, J; Trost, J; Wang, JL; Willis, J; Wu, CO; Young, NS | 1 |
| Fan, H; Hu, J; Jing, L; Li, J; Li, Y; Liu, X; Peng, G; Song, L; Xiong, Y; Yang, W; Yang, Y; Ye, L; Zhang, F; Zhang, L; Zhao, X; Zhou, K | 1 |
| Chen, Y; Dong, H; Hong, Y; Hu, H; Li, Y; Lin, S; Liu, Q; Liu, S; Liu, W; Shen, Y; Wu, D; Wu, X; Ye, B; Zhao, Y; Zhou, Y | 1 |
| Futagi, Y; Sai, Y; Shimada, T; Suga, Y | 1 |
| Kanda, Y; Mori, T; Narita, A; Nishimura, K; Wolter, KD; Yoshimatsu, H | 1 |
| Chen, Y; Hu, H; Hu, Z; Li, H; Li, Y; Lin, S; Liu, Q; Liu, S; Liu, W; Shen, J; Shen, Y; Wu, D; Wu, L; Ye, B; Yu, Q; Zhao, Y; Zheng, Z; Zhou, Y; Zhuang, H | 1 |
| Chai, X; Gong, Y; He, G; He, H; Jia, J; Li, J; Li, R; Lin, S; Liu, K; Shi, J; Wang, N; Yang, L; Yang, Y; Zhang, D | 1 |
| Chu, Y; Fang, L; Gao, Z; Li, W; Lian, Y; Liang, Q; Mao, J; Pan, H; Shi, J; Yuan, W; Zhang, L; Zhao, J | 1 |
| Fan, HH; Jing, LP; Li, JP; Li, Y; Peng, GX; Xiong, YZ; Yang, WR; Yang, Y; Ye, L; Zhang, FK; Zhang, L; Zhao, X; Zhou, K | 1 |
| Fu, R; Liu, C; Shao, Z; Wang, C; Wang, T | 1 |
| Chen, M; Chen, Y; Han, B; Wan, Z; Zhang, S; Zhuang, J | 1 |
| Aggarwal, N; Durrani, J; Groarke, EM; Lotter, J; Manley, AL; Patel, BA; Rios, O; Shalhoub, R; Wu, CO; Young, NS | 1 |
| Fan, H; Jing, L; Li, J; Li, Y; Liu, X; Xiong, Y; Yang, W; Yang, Y; Ye, L; Zhang, F; Zhang, L; Zhao, X; Zhou, K | 1 |
| Chen, M; Ding, X; Gao, D; Gao, Y; Han, B; Li, L; Liu, Q; Shao, Y; Sun, W; Suo, X; Tan, Y; Wang, L; Wang, W; Ye, F | 1 |
| Chen, Q; Chen, RL; Lin, Y; Lin, ZH; Zhang, RD | 1 |
| Fu, R; Wang, T | 1 |
| Doungngern, T; Penthinapong, T; Saelue, P; Sripakdee, W; Tanvejsilp, P | 1 |
| Chiba, S; Hattori, K; Kato, T; Kurita, N; Maruyama, Y; Nishikii, H; Obara, N; Sakamoto, T; Sakata-Yanagimoto, M; Suehara, Y; Usuki, K; Yokoyama, Y | 1 |
| Cheng, H; Han, L; Liang, X; Liu, F; Shi, X; Xu, K; Zhang, X; Zhang, Y; Zhu, J | 1 |
| Kamimura, S; Kinoshita, M; Kubota, I; Moritake, H; Nagasawa, S; Nakagawa, M; Shimonodan, H; Yamada, A | 1 |
| Yamazaki, H | 1 |
| Awada, H; Barcellini, W; Bortolotti, M; Cassanello, G; Consonni, D; Fattizzo, B; Gandhi, S; Giammarco, S; Gurnari, C; Kulasekararaj, AG; Large, J; Maciejewski, JP; Salter, S; Sica, S; Trikha, R | 1 |
| Matsukawa, T; Miyagishima, T; Nagai, J; Oshimi, K; Suto, K | 1 |
| Bacigalupo, A; Bader, P; Bosman, P; de Latour, RP; Dufour, C; Eikema, DJ; Höchsmann, B; Knol-Bout, C; Kulasekararaj, A; Marsh, J; Passweg, J; Risitano, A; Röth, A; Rovó, A; Samarasinghe, S; Schrezenmeier, H; Socié, G; Tichelli, A | 1 |
| He, HL; Hu, SY; Kong, LJ | 1 |
| Chen, XJ; Chen, YM; Guo, Y; Liu, TF; Liu, XM; Wang, SC; Yang, WY; Zhang, L; Zhu, XF; Zou, Y | 1 |
| Frączkiewicz, J; Gajek, K; Jarmoliński, T; Mielcarek-Siedziuk, M; Olejnik, I; Rosa, M; Salamonowicz-Bodzioch, M; Ussowicz, M | 1 |
| Fu, R; Hua, L; Liu, B; Liu, C; Qi, W; Shao, Y; Shao, Z; Wang, H; Wang, T; Zheng, M | 1 |
| Huang, R; Ji, D; Li, F; Peng, H; Ren, S; Zou, D | 1 |
| Alemu, L; Feng, X; Groarke, EM; Kajigaya, S; Patel, BA; Quinones Raffo, D; Young, NS; Zaimoku, Y | 1 |
| Dunbar, CE; Young, DJ | 1 |
| Cheng, H; Wang, X; Xu, KL | 1 |
| Avgerinou, G; Filippidou, M; Katsibardi, K; Kattamis, A; Roka, K; Solomou, E; Tourkantoni, N; Tsipou, H; Vlachou, A | 1 |
| Ge, M; Huang, J; Huo, J; Jin, P; Li, X; Nie, N; Ren, X; Shao, Y; Wang, M; You, Y; Zhang, J; Zheng, Y | 1 |
| Bharathi, G; Fan, H; Gao, S; Li, W; Li, Y; Meng, F; Wang, C; Wang, L; Yang, Y; Zhou, Y | 1 |
| Ahmed, P; Anwer, F; Chaudhry, QUN; Farhan, M; Ghafoor, T; Humayun, S; Iftikhar, R; Khan, MA; Khattak, TA; Mahmood, SK; Rehman, J; Risalat, A; Satti, HS; Satti, TM; Shahbaz, N; Shamshad, GU; Wahab, A | 1 |
| Scheinberg, P | 4 |
| Babushok, D; Bagg, A; Hurwitz, SN; Juusola, J; Sklarz, T; Stanley, NL | 1 |
| Atsuta, Y; Ichinohe, T; Iida, H; Katayama, Y; Kato, J; Miyamoto, T; Mori, T; Onishi, Y; Onizuka, M; Ota, S; Ozawa, Y; Shingai, N; Takenaka, K; Uchida, N; Yamaguchi, H; Yamazaki, H; Yoshioka, S | 1 |
| Obara, N | 1 |
| Ahmed, P; Ansar, I; Anwer, F; Ashraf, R; Chaudhry, QUN; Farhan, M; Ghafoor, T; Iftikhar, R; Khan, M; Khan, MA; Khattak, TA; Mahmood, SK; Marsh, J; Neupane, K; Rafae, A; Rehman, J; Satti, TM; Shahbaz, N; Shamshad, GU | 1 |
| Jia, JS | 1 |
| Aljurf, M; Alshaibani, A; de Latour, R; Dufour, C; Risitano, A | 1 |
| Fanghong, Z; Hombo, Y; Iida, H; Imada, K; Imajo, K; Kumagai, A; Maeda, T; Matsuda, A; Nakao, S; Obara, N; Tajima, T; Usuki, K | 1 |
| Abramova, AV; Chabaeva, YА; Dvirnyk, VN; Fidarova, ZT; Galtseva, IV; Kliasova, GA; Kovrigina, AM; Kulikov, SM; Luchkin, AV; Mikhaylova, EA; Obukhova, TN; Parovichnikova, EN; Savchenko, VG; Troitskaya, VV | 1 |
| Baldoni, D; Groarke, EM; Gutierrez-Rodrigues, F; Lotter, J; Patel, BA; Rios, O; Shalhoub, R; St Pierre, A; Townsley, DM; Wu, CO; Young, NS | 1 |
| Chiu, V; Hermel, D; Martynova, A; Mert, M; Weitz, IC | 1 |
| Han, B; Ruan, J | 1 |
| Menon, BS; Teh, KH | 1 |
| Cai, Y; Chang, L; Feng, J; Han, Z; Lan, Y; Liu, F; Liu, L; Yi, M; Zhang, Y; Zhu, X | 1 |
| Cheng, X; Fu, L; He, Y; Jie, M; Li, S; Wu, R; Yao, J; Zhang, L; Zhang, R; Zheng, J | 1 |
| Azuma, F; Hosokawa, K; Imi, T; Ishiyama, K; Katagiri, T; Mizumaki, H; Nakao, S; Nanya, Y; Ogawa, S; Yamazaki, H; Yoroidaka, T | 1 |
| Boals, M; Ding, J; Gray, N; Hale, M; Jacobs, T; Kang, G; Lesmana, H; Lewis, S; Reiss, U; Wang, W; Weiss, M; Wlodarski, M | 1 |
| Chaipokam, J; Charoenprasert, K; Chuncharunee, S; Issaragrisil, S; Norasetthada, L; Rojnuckarin, P; Sirijerachai, C; Wanachiwanawin, W; Wongkhantee, S | 1 |
| Akizuki, K; Hidaka, T; Ikeda, R; Shimoda, K; Takeshima, H; Yoshikawa, N | 1 |
| Chen, Z; Li, H; Li, JX; Lu, WJ; Nie, YM; Wang, Z; Xiong, H; Yang, L; Zhang, L | 1 |
| Bevans, M; Calvo, KR; Desierto, M; Desmond, R; Dumitriu, B; Dunbar, CE; Feng, X; Larochelle, A; Leuva, H; Lotter, J; Rios, O; Scheinberg, P; Townsley, DM; Valdez, J; Weinstein, B; Winkler, T; Wu, C; Young, NS | 1 |
| Chai, L; Chen, M; Deng, P; Dong, B; Li, X; Liu, J; Wei, Y; Xu, Y; Zhu, L | 1 |
| Chen, H; Cui, Q; Li, Z; Qin, L; Sha, P; Shen, H; Wang, Z; Wu, T | 1 |
| Babushok, DV; Olson, T; Peslak, SA | 1 |
| Chen, M; Han, B; Liu, C; Qiao, X; Zhou, D; Zhuang, J | 1 |
| Barraco, F; Bay, JO; Braun, T; Cahn, JY; Deconinck, E; Galambrun, C; Jubert, C; Lamy, T; Leblanc, T; Marcais, A; Mohty, M; Nguyen, S; Pasquet, M; Peffault de Latour, R; Sicre de Fontbrune, F; Socié, G; Tabrizi, R; Tavitian, S | 1 |
| Jain, N; Maiti, A; Oo, TH; Patel, KP; Popat, U; Short, NJ; Simkins, A | 1 |
| Bose, P; Khadwal, A; Khurana, H; Lad, D; Malhotra, P; Prakash, G; Sachdeva, MU; Varma, N; Varma, S; Yanamandra, U | 1 |
| Bacigalupo, A; Chen, X; Chuncharunee, S; Dufour, C; Giammarco, S; Hochsmann, B; Issaragrisil, S; Jeong, DC; Kojima, S; Oneto, R; Schrezenmeier, H; Vallejo, C; Van Lint, MT; Zheng, Y; Zhu, X | 1 |
| Chen, T; Jiang, H; Li, P; Lin, Q; Qu, Y; Sun, Z; Wang, F; Yuan, Y | 1 |
| Ay, Y; Demirag, B; Doyurgan, O; Ergin, M; Genc, S; Karapinar, TH; Köker, SA; Oymak, Y; Toret, E; Vergin, C | 1 |
| Iglesias-González, M; Monge, MF; Robles-Martínez, M | 1 |
| Chen, C; Chen, QH; Huang, JB; Lin, SF; Liu, S; Wang, J; Xue, HM; Zhang, BH | 1 |
| Geng, W; Li, Z; Song, B; Wan, C; Zhang, X | 1 |
| Atta, EH; Blum Fonseca, PB; Bonduel, M; Calado, RT; Clé, DV; de Oliveira, MM; Dias, DSP; Garanito, MP; Hamerschlak, N; Lima, CBL; Medeiros, LA; Pazin-Filho, A; Saad, STO; Salvino, MA; Scheinberg, P; Sciuccati, G | 1 |
| Fukuda, A; Kambara, Y; Kiguchi, T; Kuroi, T; Masunari, T; Meguri, Y; Sezaki, N; Urata, T; Yamamoto, A | 1 |
| Fang, J; Lin, D; Lin, L; Lin, X; Liu, C; Sunlong, Q; Wang, Y | 1 |
| Cabrera, ME; Cardemil, D; León, P; Osorio, R; Peña, C; Puga, B; Valladares, X | 1 |
| Gao, F; Sha, D; Wang, F; Xin, X; Zhang, J | 1 |
| Arai, S; Koya, J; Kurokawa, M; Matsuda, K; Nakamura, F; Nakazaki, K | 1 |
| Anand, A; Jain, P; Panchal, H; Parikh, S; Patel, A; Patel, K; Shah, K; Shah, S | 1 |
| Bian, Z; Lu, S; Qiao, X; Song, X; Zhou, H; Zhou, N | 1 |
| Church, DL; Franko, A; Perry, S; Ugarte-Torres, A | 1 |
| Bacigalupo, A | 2 |
| Guliani, A; Kumar, S; Vinay, K | 1 |
| Cao, J; Cheng, H; Larochelle, A; Wang, X; Xu, KL; Zhou, D | 1 |
| Babushok, DV; Duke, JL; Huang, Y; Monos, DS; Olson, TS; Oved, JH; Stanley, N; Teachey, DT | 1 |
| Arranto, C; Baldomero, H; Gerull, S; Halter, JP; Heim, D; Kleber, M; Medinger, M; Passweg, JR; Soltermann, Y | 1 |
| Ames, NJ; Barb, JJ; Cashion, AK; Childs, R; Faller, LL; Kim, H; Mudra, SE; Paster, BJ; Ranucci, A; Townsley, DM; Wallen, GR | 1 |
| Alashkar, F; Dührsen, U; Herich-Terhürne, D; Oelmüller, M; Röth, A; Schmitz, C; Turki, AT; Vance, C | 1 |
| Hermans, BCM; Kuijper, PHM; Nieuwenhuizen, L; van Oostrum, NHM; Zanders, MM | 1 |
| Chen, XQ; Fang, JP; Han, B; He, HL; Hu, JD; Jin, J; Li, W; Liang, YM; Liu, F; Shi, HX; Tang, JY; Wang, SQ; Wu, DP; Wu, LQ; Xia, LH; Ye, TZ; Zhang, DH; Zhang, FK; Zhang, X; Zhou, F; Zhu, HL; Zhu, XF | 1 |
| Atay, H; Kelkitli, E; Turgut, M | 1 |
| Cardarelli, L; Chiaretti, S; Diverio, D; Foà, R; Giona, F; Mancini, F; Miano, M; Moleti, ML; Nanni, M; Palumbo, G; Peragine, N; Santopietro, M; Testi, AM; Zhang, K | 1 |
| Chang, LX; Chen, X; Chen, XJ; Chen, YM; Guo, Y; Liu, F; Liu, LP; Liu, TF; Ruan, M; Yang, WY; Yi, MH; Zhang, FK; Zhang, L; Zhou, K; Zhu, XF; Zou, Y | 1 |
| Cheng, L; He, GS; Lin, SY; Liu, J; Liu, XQ; Lu, XY; Wu, XM; Yang, Y; Yin, H | 1 |
| Bansal, D; Jain, R; Trehan, A; Varma, N | 1 |
| Dufour, C; Pierri, F | 1 |
| Cho, BS; Cho, SG; Cho, SY; Eom, KS; Han, E; Kim, HJ; Kim, YJ; Lee, JW; Lee, S; Lee, SE; Min, CK; Min, GJ; Park, S; Park, SS; Yoon, JH | 1 |
| Fuyama, M; Ikeda, H; Isoyama, K | 1 |
| Hapgood, G; Hoy, JF; Jane, SM; Morrissey, CO | 1 |
| Ge, M; Huang, J; Huang, Z; Li, X; Nie, N; Shao, Y; Shi, J; Zhang, J; Zheng, Y | 3 |
| Chen, SQ; Jacqz-Aigrain, E; Ni, SQ; Wang, J; Zeng, S; Zhao, W; Zhao, ZY | 1 |
| Akin, M; Ay, Y; Aydinok, Y; Balkan, C; Karadaş, N; Karapinar, DY; Kavakli, K | 1 |
| Chen, C; Fang, JP; Fu, RT; Huang, K; Huang, SL; Xu, HG; Xue, HM | 1 |
| Das, S; Nair, V; Sharma, A; Sharma, S; Sondhi, V | 2 |
| Cui, JY; Li, YX; Ran, XH; Ren, CA; Sheng, ZX; Wang, BH; Zhang, MH | 1 |
| Chen, XJ; Hama, A; Ito, M; Kojima, S; Yang, WY; Zhang, PH; Zhu, XF | 1 |
| Barrett, J; Childs, RW; Cook, L; Donohue, T; Geller, N; Khuu, H; Kurlander, R; Leitman, S; Pantin, J; Ramos, C; Shah, AA; Stroncek, D; Tian, X; Young, NS | 1 |
| Demkow, U; Matysiak, M; Panasiuk, A; Pawelec, K; Salamonowicz, M | 1 |
| Bartel, C; Grouven, U; Peinemann, F | 1 |
| Chiba, S; Hasegawa, Y; Kurita, N; Nishikii, H; Obara, N; Sakamoto, T; Sakata-Yanagimoto, M; Suzukawa, K; Yokoyama, Y | 1 |
| Fan, HH; Jing, LP; Li, JP; Li, Y; Peng, GX; Song, L; Xiong, YY; Yang, WR; Ye, L; Zhang, FK; Zhang, L; Zhao, X; Zhou, K | 1 |
| Dong, QE; Fu, R; Guan, J; Li, LJ; Liu, CY; Liu, H; Qu, W; Ruan, EB; Shao, ZH; Song, J; Wang, GJ; Wang, HQ; Wang, XM; Wu, YH; Xing, LM | 1 |
| Bertrand, A; Bertrand, Y; Bleyzac, N; Philippe, M; Plantaz, D | 1 |
| Czuchlewski, DR; George, TI; Golardi, N; Myers, JB; Saffer, H; Sramek, JE | 1 |
| Cho, B; Chung, NG; Jeong, DC; Kim, HK; Kojima, S; Kosaka, Y; Muramatsu, H; Ohara, A; Ruan, M; Takahashi, Y; Yang, W; Zhu, X; Zou, Y | 1 |
| Afanasyev, B; Babenko, E; Bondarenko, S; Golubovskaya, I; Ivanova, M; Kozlov, V; Kruchkova, I; Kulagin, A; Lisukov, I; Pronkina, N; Sipol, A; Stancheva, N; Vavilov, V | 1 |
| Bennett, C; Bertuch, A; Bessler, M; Coates, T; Corey, S; Dror, Y; Huang, J; Lipton, J; Olson, TS; Reiss, UM; Rogers, ZR; Shimamura, A; Sieff, C; Vlachos, A; Walkovich, K; Wang, W; Williams, DA | 1 |
| Abe, T; Fujii, S; Fujita, M; Iyama, S; Jomen, W; Kato, J; Kobune, M; Kuroda, H; Maeda, M; Matsuno, T; Miyanishi, K; Nagashima, K; Sakurai, T; Sato, M; Yamada, M | 1 |
| Kulasekararaj, AG; Marsh, JC | 1 |
| Hamamoto, K; Inoue, M; Kobayashi, R; Kojima, S; Muramatsu, H; Ohara, A; Ohga, S; Ohtsuka, Y; Shichino, H; Shimada, H; Takahashi, Y; Yabe, H; Yagasaki, H | 1 |
| Dumitriu, B; Rios, O; Scheinberg, P; Townsley, D; Weinstein, B; Wu, CO; Young, NS | 1 |
| Asano, J; Shinzato, I; Takafuta, T; Tanaka, Y; Ueda, R | 1 |
| Füreder, W; Jäger, E; Paulitsch-Buckingham, A; Rabitsch, W; Schwarzinger, I; Sperr, WR; Valent, P | 1 |
| Darrigo, LG; Dias, JB; Grecco, CE; Moraes, DA; Pieroni, F; Rodrigues, MC; Simões, BP; Sobral, AC; Stracieri, AB | 1 |
| Nakao, S | 5 |
| Fu, R; Guan, J; Li, L; Liu, C; Liu, H; Qu, W; Ruan, E; Shao, Z; Song, J; Wang, G; Wang, H; Wu, Y; Xing, L | 1 |
| Cheng, YF; Hao, YL; Hou, M; Hou, XY; Ma, SH; Peng, J; Ren, J; Sun, L; Sun, YX; Xu, CG; Zhang, FK; Zhang, MH; Zhen, JH | 1 |
| Bhattacharya, R; Biswas, A; Park, E | 1 |
| Dufour, C; Marsh, J; Samarasinghe, S | 1 |
| An, W; Cai, X; Chang, L; Chen, X; Chen, Y; Guo, Y; Liu, F; Liu, T; Liu, X; Qi, B; Ruan, M; Wang, S; Yang, W; Zhang, J; Zhang, L; Zhou, J; Zhu, X; Zou, Y | 1 |
| Chen, J; Gao, YJ; Jiang, H; Lu, FJ; Luo, CJ; Luo, CY; Pan, C; Tang, JY; Xue, HL; Ye, QD; Zhou, M; Zhu, XH | 1 |
| Guan, J; Jiang, L; Wei, J; Xu, J; Yin, J; Zhang, Y; Zhao, L; Zhu, X | 1 |
| Rios, O; Scheinberg, P; Weinstein, B; Wu, CO; Young, NS | 1 |
| Araki, R; Fujiki, T; Koizumi, S; Kuroda, R; Maeba, H; Mase, S; Nishimura, R; Yachie, A | 1 |
| Crescenzio, N; Decimi, V; Doria, A; Dufour, C; Foglia, L; Longoni, D; Marra, N; Martire, B; Pagliano, S; Palumbo, G; Pillon, M; Ramenghi, U; Ruggiero, A; Saracco, P; Svahn, J; Timeus, F; Vallero, S | 1 |
| Li, D; Wang, H; Wang, Z; Yan, H; Zheng, X | 1 |
| Bodh, V; Datta, AK; Guru Murthy, GS; Malhotra, P; Varma, N; Varma, S | 1 |
| Bryan, J; Kadia, TM; Rexwinkle, A; Willis, L | 1 |
| Kato, K; Kobayashi, R; Kojima, S; Kosaka, Y; Kudo, K; Morimoto, A; Muramatsu, H; Ohara, A; Ohga, S; Suzuki, R; Takahashi, Y; Watanabe, K; Yabe, H; Yagasaki, H; Yoshida, N | 1 |
| Bornhäuser, M; Ehninger, G; Helas, S; Hofmann, WK; Jann, JC; Mossner, M; Nowak, D; Platzbecker, U; Röllig, C; Schönefeldt, C; Sockel, K; Thiede, C; Wermke, M | 1 |
| Chen, HF; Cui, QY; Jin, LJ; Li, ZY; Qin, LM; Ren, YY; Shen, HS; Tang, JQ; Wang, J; Wu, TQ; Xu, BX; Zhu, JJ | 1 |
| Bao, JA; Ding, XL; Miao, LY; Xue, L; Zhang, JJ; Zhang, WW | 1 |
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| Geary, CG; Gordon-Smith, EC; Harrison, CJ; Hows, JM; Marsh, JC; Philpott, NJ | 1 |
| Bacigalupo, A; Hows, J; Ilhan, O; Ljungman, P; Locasciulli, A; Marin, P; Marsh, J; McCann, S; Passweg, J; Raghavachar, A; Schrezenmeier, H; Socie, G; Tichelli, A | 1 |
| Kondo, Y; Matsuda, T; Miura, Y; Nakao, S; Shiobara, S; Sugimori, N; Takamatsu, H; Takami, A; Yachie, A; Yamazaki, H; Zeng, W | 1 |
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| Arcese, W; Bacigalupo, A; Di Bona, E; Locasciulli, A; Locatelli, F | 1 |
| Shao, Z; Zhang, Y; Zheng, Y | 1 |
| Shao, Z; Zhang, N | 1 |
| Chung, IJ; Hwang, TJ; Kim, HJ; Kook, H; Kwak, JY; Lee, JJ; Na, JA; Park, MR; Sohn, SK | 1 |
| Brodsky, RA; Jones, RJ | 1 |
| Chojnowski, K; Góra-Tybor, J; Robak, E; Robak, T; Strzelecka, B; Sysa-Jedrzejowska, A; Waszczykowska, E | 1 |
| Chuhjo, T; Mizoguchi, H; Nakao, S; Shiobara, S; Teramura, M; Wang, H; Yamazaki, H | 1 |
| Ebata, K; Hirose, Y; Kim, CG; Masaki, Y; Ogawa, N; Okada, J; Sugai, S; Wano, Y | 1 |
| Antin, JH; Bierer, BE; Cowan, MJ; Ho, WG; Jiao, J; Kaizer, H; Lazarus, HM; Linker, C; Miller, KB; Petersen, FB; Petrarca, MA; Schiller, GJ; Small, T; Territo, MC; Tonetta, SA; Wingard, JR; Winston, DJ; Wolff, SN | 1 |
| Diagileva, OA; Iadrikhinskaia, VN; Kokhno, AV; Kozinets, DI; Kulikov, SM; Maslova, ER; Mikhaĭlova, EA; Savchenko, VG; Sokolov, AN; Tikhonova, LIu; Tiurina, NG; Ustinova, EN | 1 |
| Durrant, S; Gillett, EA; Lockwood, L; Mollee, P; Morton, J; Rowell, J; Woodward, N | 1 |
| Ando, K; Iguchi, T; Ito, Y; Katagiri, T; Kimura, Y; Masuda, M; Miyazawa, K; Mizoguchi, H; Ohyashiki, K; Shimamoto, T; Tauchi, T; Yaguchi, M | 1 |
| Domingues-Martins, M; França, CM; Pallotta Filho, RS; Soares de Araújo, N; Volpe, A | 1 |
| Chu, Y; Shao, Z; Zheng, Y | 1 |
| Adachi, Y; Iki, S; Kazama, H; Matsuya, S; Urabe, A; Usuki, K | 1 |
| Asaka, M; Chiba, K; Hashino, S; Izumiyama, K; Suzuki, S; Takahata, M | 1 |
| Atkinson, JC; Baccaglini, L; Brennan, MT; Kingman, A; Nunez, O; Pillemer, SR; Sankar, V; Young, NS | 1 |
| Ferrant, A; Straetmans, N; Triffet, A | 1 |
| Adachi, M; Akaike, J; Hayashi, T; Hinoda, Y; Hirayama, T; Imai, K; Kasahara, K; Minami, T; Takahashi, S; Takahashi, T | 1 |
| Bacigalupo, A; Endo, T; Fujimoto, K; Koike, T; Nakao, S; Nishio, M; Sakai, T; Sawada, K; Takashima, H | 1 |
| Luo, X; Yu, R; Zhu, X | 1 |
| Acevedo, A; Escudero, A; Fernández-Rañada, JM; Gil-Fernández, JJ; Martínez, E; Martínez-Chamorro, C | 1 |
| Jha, VC; Rai, M; Shukla, J; Singh, VP; Sundar, S | 1 |
| Arranz, R; Brunet, S; Bueno, J; Cabrera, R; Carreras, E; Conde, E; Conde, JG; Fernández-Rañada, JM; Iriondo, A; Maldonado, J; Marín, P; Odriozola, J; Pajuelo, FJ; Petit, J; Rodriguez-Salvanés, F; Sanz, MA | 1 |
| Haas, RJ; Lang, T; Otté, JB; Schmid, I; Stachel, D | 1 |
| Gao, R; Jin, J; Lin, S; Luo, X; Shen, Y; Yu, R; Zhou, Y; Zhu, N | 1 |
| Chen, G; Chu, Y; He, G; He, H; Li, K; Liu, H; Qian, L; Shao, Z; Shi, J; Song, L; Yang, C; Yang, T; Zhang, H; Zhang, Y; Zhao, M; Zheng, Y | 1 |
| Li, W; Peng, J; Ren, C; Wang, W; Xu, C; Zhang, M; Zhang, T | 1 |
| Bittencourt, E; Gluckman, E; Leymarie, V; Noguera, ME; Sigaux, F; Socié, G | 1 |
| Bright, R; Damon, L; Eisendrath, S | 1 |
| Claviez, A; Dreger, P; Glass, B; Suttorp, M | 1 |
| Hiramatsu, A; Imamura, A; Kanakura, M; Kato, Y; Mihara, H; Miwa, H; Nitta, M; Sato, A; Tajima, E; Wakabayashi, M | 1 |
| Barrett, J; Kook, H; Lottemann, C; Maciejewski, JP; Nakamura, R; Risitano, AM; Wlodarski, M; Young, NS; Zeng, W | 1 |
| Baron, F; Baudoux, E; Beguin, Y; Fillet, G; Matus, G; Sautois, B | 1 |
| Khan, SP; Rodriguez, V | 1 |
| Goldman, J; Kumar, M | 1 |
| Kalinin, NN; Mikhaĭlova, EA; Pashinin, AN; Pustovoĭt, LA; Savchenko, VG; Ustinova, EN | 1 |
| Gutorov, SL; Idel'son, LI; Kravchenko, SK; Kremenetskaia, AM; Pivnik, AV; Pustovoĭt, LA; Rasstrigin, NA | 1 |
| Matusda, T; Nakao, S; Shiobara, S; Takamatsu, H; Yamaguchi, M | 1 |
| Chia, LG; Gau, JP; Hwang, WL; Young, JH | 1 |
| Arioka, H; Ishikawa, Y; Kobayashi, R; Naito, H | 1 |
| Goudsmit, R; Leeksma, OC; Thomas, LL; van der Lelie, J; van Oers, MH; von dem Borne, AE | 1 |
| Baruchel, A; Boogaerts, M; Briere, J; Donadio, D; Esperou-Bourdeau, H; Gluckman, E; Janvier, M; Leporrier, M; Leverger, G; Reiffers, J | 2 |
| Mehta, BC; Mehta, J; Singhal, S | 1 |
| Matsuda, T; Miyawaki, T; Nakao, S; Shiobara, S; Taniguchi, T; Yamaguchi, M; Yokoi, T | 1 |
| Calhoun, L; Champlin, RE; Gajewski, JL; Ho, WG; Hunt, LA; Landaw, EM; Lyddane, NR; O'Rourke, S; Petz, LD; Schiller, GJ | 1 |
| Crump, M; Curtis, JE; Larratt, LM; Lipton, JH; Maki, E; Meharchand, JM; Messner, HA; Minden, MD | 1 |
| Björkholm, M | 1 |
| Robak, T | 1 |
| Raghavachar, A; Schlander, M; Schrezenmeier, H | 1 |
| Amri, F; Bertrand, Y; Capdeville, R; Ffrench, M; Philippe, N | 1 |
| Bacigalupo, A; Biggs, JC; Camitta, BM; Champlin, RE; Gale, RP; Gluckman, E; Gordon-Smith, EC; Horowitz, MM; Hows, JM; Marmont, AM | 1 |
| Speck, B | 1 |
| Bruggers, CS; Friedman, HS; Kurtzberg, J | 1 |
| Espérou-Bourdeau, H; Gluckman, E | 1 |
| Frickhofen, N; Herrmann, F; Köchling, G; Lange, W; Lindemann, A; Mertelsmann, RH; Raghavachar, A; Schrezenmeier, H | 1 |
| Bourdeau-Esperou, H; Cosset, JM; Devergie, A; Gluckman, E; Socie, G; Traineau, R | 1 |
| Abbott, GD; Baker, BW; Beard, ME; Heaton, DC; Smith, MP; Spearing, RL | 1 |
65 review(s) available for cyclosporine and Anemia, Aplastic
| Article | Year |
|---|---|
New Trends in Nontransplant Therapy for Acquired Aplastic Anemia.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Humans; Immunosuppression Therapy; Immunosuppressive Agents | 2022 |
The efficacy and safety of cyclosporine A plus androgen versus androgen alone for adult patients with non-severe aplastic anemia in China: a meta-analysis of randomized controlled trials.
Topics: Adult; Androgens; Anemia, Aplastic; Cyclosporine; Hirsutism; Humans; Hyperplasia; Randomized Controlled Trials as Topic | 2022 |
Multiple hepatocellular adenomas associated with long-term administration of androgenic steroids for aplastic anemia: A case report and literature review.
Topics: Abdominal Pain; Adenoma, Liver Cell; Adolescent; Adult; Aftercare; Aged; Anemia, Aplastic; Biopsy, Fine-Needle; Cyclosporine; Diagnostic Errors; Female; Fever; Humans; Immunosuppressive Agents; Liver Abscess; Liver Neoplasms; Male; Middle Aged; Shock, Hemorrhagic; Stanozolol; Testosterone Congeners; Tomography, X-Ray Computed | 2020 |
Novel therapeutic choices in immune aplastic anemia.
Topics: Anemia, Aplastic; Animals; Antilymphocyte Serum; Cyclosporine; Hematopoietic Stem Cell Transplantation; Horses; Humans; Immunosuppressive Agents; Salvage Therapy | 2020 |
Allogeneic hematopoietic stem cell transplantation in aplastic anemia: current indications and transplant strategies.
Topics: Age Factors; Allografts; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Graft Rejection; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppression Therapy; Methotrexate; Risk Factors; Transplantation Conditioning; Unrelated Donors; Vidarabine | 2021 |
Hepatitis-Associated Aplastic Anemia.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Hepatitis; Humans; Immunosuppression Therapy | 2022 |
Diagnosis and Treatment of Aplastic Anemia.
Topics: Anemia, Aplastic; Bone Marrow Diseases; Bone Marrow Transplantation; Cyclosporine; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppression Therapy; Siblings; Tissue Donors | 2017 |
Recent Advances and Long-Term Results of Medical Treatment of Acquired Aplastic Anemia: Are Patients Cured?
Topics: Alemtuzumab; Anemia, Aplastic; Animals; Antilymphocyte Serum; Benzoates; Cyclosporine; Humans; Hydrazines; Immunosuppression Therapy; Immunosuppressive Agents; Pyrazoles; Recurrence; Treatment Outcome | 2018 |
Activity of eltrombopag in severe aplastic anemia.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Benzoates; Cyclosporine; Disease-Free Survival; Humans; Hydrazines; Pyrazoles; Severity of Illness Index; Survival Rate | 2018 |
Alternative donor transplants for severe aplastic anemia.
Topics: Allografts; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Severity of Illness Index; Unrelated Donors | 2018 |
Management of aplastic anemia after failure of frontline immunosuppression.
Topics: Alemtuzumab; Androgens; Anemia, Aplastic; Antilymphocyte Serum; Clinical Trials as Topic; Cord Blood Stem Cell Transplantation; Cyclophosphamide; Cyclosporine; Disease Management; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Peptides; Practice Guidelines as Topic; Recurrence; Remission Induction; Survival Analysis; Unrelated Donors | 2019 |
[A case of focal segmental glomerulosclerosis with nephrotic syndrome after hematopoietic stem cell transplantatation for aplastic anemia].
Topics: Anemia, Aplastic; Biopsy; Child; Cyclosporine; Female; Glomerulosclerosis, Focal Segmental; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Kidney Glomerulus; Microscopy, Electron; Mycophenolic Acid; Nephrotic Syndrome; Proteinuria; Treatment Outcome | 2013 |
Immune-mediated cytopenias in human immunodeficiency virus: the first reported case of idiopathic aplastic anaemia successfully treated with immunosuppression.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Female; HIV Infections; Humans; Immunity, Cellular; Immunosuppression Therapy; Immunosuppressive Agents; Middle Aged; Treatment Outcome | 2013 |
First-line allogeneic hematopoietic stem cell transplantation of HLA-matched sibling donors compared with first-line ciclosporin and/or antithymocyte or antilymphocyte globulin for acquired severe aplastic anemia.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Graft Rejection; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Histocompatibility; HLA Antigens; Humans; Immunosuppressive Agents; Mendelian Randomization Analysis; Siblings; T-Lymphocytes; Transplantation, Homologous | 2013 |
Management of the refractory aplastic anemia patient: what are the options?
Topics: Adult; Age Factors; Alemtuzumab; Allografts; Anemia, Aplastic; Antibodies, Monoclonal, Humanized; Antilymphocyte Serum; Antineoplastic Agents; Benzoates; Bone Marrow Diseases; Bone Marrow Failure Disorders; Cyclosporine; Disease-Free Survival; Hematopoietic Stem Cell Transplantation; Hemoglobinuria, Paroxysmal; Humans; Hydrazines; Immunosuppression Therapy; Immunosuppressive Agents; Middle Aged; Pyrazoles; Siblings; Survival Rate; Unrelated Donors | 2013 |
[Recent issues and prospects of the treatment of aplastic anemia].
Topics: Anemia, Aplastic; Animals; Antilymphocyte Serum; Benzoates; Biomarkers; Cyclosporine; Drug Therapy, Combination; Herpesvirus 4, Human; Humans; Hydrazines; Immunosuppressive Agents; Lymphoproliferative Disorders; Prednisolone; Pyrazoles; Receptors, Thrombopoietin; Risk; Severity of Illness Index; Thrombopoietin | 2014 |
Recent developments in drug therapy for aplastic anemia.
Topics: Alemtuzumab; Anemia, Aplastic; Animals; Antibodies, Monoclonal, Humanized; Antilymphocyte Serum; Benzoates; Clinical Trials as Topic; Cyclosporine; Daclizumab; Humans; Hydrazines; Immunoglobulin G; Immunosuppressive Agents; Pyrazoles; Recurrence; Salvage Therapy; Survival Rate | 2014 |
[Recent progress in the management of aplastic anemia].
Topics: Acute Disease; Anemia, Aplastic; Antilymphocyte Serum; Benzoates; Chronic Disease; Cyclosporine; Disease Progression; Hematopoiesis; Humans; Hydrazines; Immunosuppressive Agents; Pyrazoles | 2014 |
[Treatment of aplastic anemia in children].
Topics: Allografts; Anemia, Aplastic; Autoantibodies; Child; Cyclosporine; Diagnosis, Differential; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents | 2014 |
Eltrombopag for the treatment of aplastic anemia: current perspectives.
Topics: Alemtuzumab; Anemia, Aplastic; Antibodies, Monoclonal, Humanized; Antilymphocyte Serum; Benzoates; Cyclophosphamide; Cyclosporine; Hematopoietic Stem Cells; Humans; Hydrazines; Immunosuppressive Agents; Pyrazoles | 2016 |
Severe fatigue: could it be aplastic anemia?
Topics: Algorithms; Anemia, Aplastic; Antilymphocyte Serum; Blood Cell Count; Bone Marrow Examination; Cyclosporine; Decision Trees; Fatigue; Humans; Immunosuppressive Agents; Male; Middle Aged; Prognosis; Rare Diseases; Remission Induction; Severity of Illness Index; Stem Cell Transplantation; Treatment Outcome | 2008 |
ATG plus cyclosporine reduces all-cause mortality in patients with severe aplastic anemia--systematic review and meta-analysis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Drug Therapy, Combination; Humans; Middle Aged; Randomized Controlled Trials as Topic; Treatment Outcome | 2008 |
Lymphoproliferative disorders after immunosuppressive therapy for aplastic anemia: a case report and literature review.
Topics: Anemia, Aplastic; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocols; Asian People; Cyclophosphamide; Cyclosporine; Doxorubicin; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Japan; Lymphoma, Large B-Cell, Diffuse; Male; Middle Aged; Prednisolone; Radionuclide Imaging; Radiotherapy; Rituximab; Skin Neoplasms; Splenectomy; Splenic Neoplasms; Tomography, X-Ray Computed; Vincristine | 2009 |
Diagnosis and treatment of acquired aplastic anemia.
Topics: Age Factors; Anemia, Aplastic; Animals; Antilymphocyte Serum; Bone Marrow Transplantation; Cyclosporine; Female; Fetal Blood; Humans; Immunosuppressive Agents; Intercellular Signaling Peptides and Proteins; Male; Pregnancy; Prognosis | 2009 |
Acquired aplastic anemia in childhood.
Topics: Anemia, Aplastic; Animals; Antilymphocyte Serum; Cyclosporine; Filgrastim; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Recombinant Proteins | 2009 |
[Recent progress in the diagnosis and treatment of aplastic anemia in children].
Topics: Anemia, Aplastic; Animals; Antilymphocyte Serum; Bone Marrow Transplantation; Child; Combined Modality Therapy; Cyclosporine; Diagnosis, Differential; Drug Therapy, Combination; Granulocyte Colony-Stimulating Factor; Histocompatibility; HLA Antigens; Humans; Immunosuppression Therapy; Myelodysplastic Syndromes; Rabbits; Sirolimus | 2009 |
[Management of patients with aplastic anemia and related disorders].
Topics: Anemia, Aplastic; Antibodies, Monoclonal; Antilymphocyte Serum; Cyclosporine; Diagnosis, Differential; Drug Therapy, Combination; Early Diagnosis; Flow Cytometry; Humans; Magnetic Resonance Imaging | 2009 |
Immunosuppressive therapies in the management of immune-mediated marrow failures in adults: where we stand and where we are going.
Topics: Adult; Algorithms; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Diseases; Bone Marrow Failure Disorders; Cyclosporine; Hemoglobinuria, Paroxysmal; History, 20th Century; Humans; Immunosuppression Therapy; Immunosuppressive Agents | 2011 |
[Successful treatment with immunosuppressive therapy for aplastic anemia developed after resection of thymoma].
Topics: Anemia, Aplastic; Autoantibodies; Cyclosporine; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Male; Middle Aged; Myasthenia Gravis; Postoperative Complications; Thymectomy; Thymoma; Thymus Neoplasms; Time Factors; Treatment Outcome | 2011 |
Rabbit ATG for aplastic anaemia treatment: a backward step?
Topics: Anemia, Aplastic; Animals; Antilymphocyte Serum; Cyclosporine; Humans; Immunosuppressive Agents; Prognosis; Rabbits; Randomized Controlled Trials as Topic; Risk Assessment; Sensitivity and Specificity; Severity of Illness Index; Survival Analysis; Treatment Outcome | 2011 |
Immunosuppressive therapies in the management of acquired immune-mediated marrow failures.
Topics: Anemia, Aplastic; Animals; Antilymphocyte Serum; Bone Marrow Diseases; Bone Marrow Failure Disorders; Cyclosporine; Hemoglobinuria, Paroxysmal; Horses; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Rabbits | 2012 |
Posterior reversible encephalopathy syndrome in childhood: report of four cases and review of the literature.
Topics: Adolescent; Anemia, Aplastic; Anticonvulsants; Antihypertensive Agents; Child; Cyclosporine; Early Diagnosis; Epilepsy, Tonic-Clonic; Female; Glomerulonephritis; Humans; Hypertensive Encephalopathy; IgA Vasculitis; Immunosuppressive Agents; Intellectual Disability; Magnetic Resonance Imaging; Male; Nephrotic Syndrome; Posterior Leukoencephalopathy Syndrome; Postoperative Complications; Stem Cell Transplantation; Streptococcal Infections; Vision Disorders | 2012 |
Antibodies in the treatment of aplastic anemia.
Topics: Alemtuzumab; Anemia, Aplastic; Animals; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antilymphocyte Serum; Clinical Trials as Topic; Cyclosporine; Daclizumab; Drug Interactions; Horses; Humans; Immunoglobulin G; Immunosuppressive Agents; Immunotherapy; Rabbits; Rituximab; Swine | 2012 |
Emphysematous gastritis and severe aplastic anemia.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Cholelithiasis; Cyclosporine; Emphysema; Female; Gastritis; Granulocyte Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Meropenem; Methylprednisolone; Metronidazole; Middle Aged; T-Lymphocytes; Thienamycins; Tomography, X-Ray Computed | 2003 |
Persistent remission after immunosuppressive therapy of hairy cell leukemia mimicking aplastic anemia: two case reports.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Cells; Clone Cells; Cyclosporine; Diagnosis, Differential; Drug Therapy, Combination; Female; Humans; Immunophenotyping; Immunosuppressive Agents; Leukemia, Hairy Cell; Male; Middle Aged; Remission Induction | 2003 |
Pregnancy associated aplastic anemia--a series of 10 cases with review of literature.
Topics: Abortion, Spontaneous; Adult; Androgens; Anemia, Aplastic; Blood Component Transfusion; Combined Modality Therapy; Cyclosporine; Fatal Outcome; Female; Fetal Death; Fetal Growth Retardation; Humans; Immunosuppressive Agents; India; Infant, Newborn; Infant, Small for Gestational Age; Intestinal Atresia; Jejunum; Male; Pregnancy; Pregnancy Complications, Hematologic; Pregnancy Outcome; Remission, Spontaneous | 2002 |
[Treatment of acquired a plastic anemia: an update].
Topics: Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Transplantation; Clinical Trials as Topic; Combined Modality Therapy; Cyclosporine; Drug Therapy, Combination; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Histocompatibility; HLA Antigens; Humans; Immunosuppressive Agents; Prognosis; Transplantation Conditioning; Transplantation, Homologous | 2004 |
Reduced-intensity conditioning and blood stem cell transplantation from an HLA-identical sibling for severe aplastic anaemia: two patients with successful engraftment but a fatal post-transplant lymphoproliferative disorder in the other.
Topics: Adrenal Cortex Hormones; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Diabetes Mellitus, Type 2; Drug Resistance; Epstein-Barr Virus Infections; Fatal Outcome; Histocompatibility; Humans; Immunosuppressive Agents; Lymphoma, B-Cell; Male; Middle Aged; Peripheral Blood Stem Cell Transplantation; Prednisone; Siblings; T-Lymphocytes; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Tumor Virus Infections | 2004 |
Management of acquired aplastic anaemia.
Topics: Anemia, Aplastic; Combined Modality Therapy; Cyclosporine; Humans; Immunosuppressive Agents | 2005 |
[Immunosuppressive therapy for aplastic anemia--review].
Topics: Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Drug Therapy, Combination; Erythropoietin; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Recombinant Proteins | 2005 |
[Efficacy of anti-thymocyte globulin and cyclosporin A combined therapy in aplastic anemia complicated with limited cutaneous systemic sclerosis].
Topics: Aged; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Female; Granulocyte Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Methylprednisolone; Penicillamine; Pulse Therapy, Drug; Scleroderma, Systemic | 2005 |
[Cyclosporin].
Topics: Anemia, Aplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Autoimmune Diseases; Behcet Syndrome; Calcineurin Inhibitors; Cyclosporine; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Food-Drug Interactions; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Transplantation | 2005 |
[Evidence-based medicine for treatment of aplastic anemia in children].
Topics: Adolescent; Anemia, Aplastic; Autoantibodies; Child; Cyclophosphamide; Cyclosporine; Drug Therapy, Combination; Evidence-Based Medicine; Hematopoietic Stem Cell Transplantation; Histocompatibility; HLA Antigens; Humans; Immunosuppressive Agents; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Survival Rate | 2005 |
[Treatment of adult patients with aplastic anemia in Japan].
Topics: Adult; Anabolic Agents; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Transplantation; Cyclosporine; Drug Therapy, Combination; Evidence-Based Medicine; Granulocyte Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Japan; Methenolone; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Severity of Illness Index | 2005 |
[Aplastic anemia and pure red cell aplasia].
Topics: Adrenal Cortex Hormones; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Transplantation; Cyclophosphamide; Cyclosporine; Drug Therapy, Combination; Granulocyte Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Plasma Exchange; Red-Cell Aplasia, Pure; Severity of Illness Index | 2008 |
[Aplastic anemia].
Topics: Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Granulocyte-Macrophage Colony-Stimulating Factor; Humans | 1994 |
Treatment of aplastic anaemia with antilymphocyte globulin and cyclosporin.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Humans; Immunosuppressive Agents | 1995 |
Use of hematopoietic growth factors for treatment of aplastic anemia.
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Clinical Trials as Topic; Cohort Studies; Cyclosporine; Europe; Female; Hematopoiesis; Hematopoietic Cell Growth Factors; Humans; Immunosuppressive Agents; Infant; Japan; Male; Randomized Controlled Trials as Topic; Retrospective Studies | 1996 |
What is the most effective treatment of children with severe aplastic anemia who lack a matched sibling donor?
Topics: Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Transplantation; Child; Clinical Trials as Topic; Combined Modality Therapy; Cyclosporine; Fetal Blood; Graft Survival; Graft vs Host Disease; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Cell Growth Factors; Hematopoietic Stem Cell Transplantation; Histocompatibility; Humans; Immunosuppressive Agents; Interleukin-3; Methylprednisolone; Nuclear Family; Recombinant Fusion Proteins; T-Lymphocytes; Transplantation, Homologous | 1996 |
Rapid progression of acquired amegakaryocytic thrombocytopenia to aplastic anemia.
Topics: Anemia, Aplastic; Bone Marrow; Cyclosporine; Disease Progression; Erythrocyte Transfusion; Fatal Outcome; Humans; Male; Megakaryocytes; Middle Aged; Platelet Transfusion; Purpura, Thrombocytopenic | 1997 |
Immune mechanism of aplastic anemia.
Topics: Anemia, Aplastic; Animals; Autoimmune Diseases; Bone Marrow; CD4-Positive T-Lymphocytes; Cyclosporine; Disease Susceptibility; Gene Rearrangement, beta-Chain T-Cell Antigen Receptor; Hematopoiesis; HLA-DR Antigens; Humans; Immunosuppressive Agents; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Receptors, Antigen, T-Cell, alpha-beta; T-Lymphocyte Subsets | 1997 |
[Antithymocyte globulin therapy].
Topics: Anemia, Aplastic; Animals; Antilymphocyte Serum; Cyclosporine; Drug Therapy, Combination; Granulocyte Colony-Stimulating Factor; Humans; Immunotherapy | 1998 |
Myelodysplastic syndrome (MDS) with unbalanced t(1;7) after severe aplastic anemia (SAA) in childhood as a variant form of monosomy 7.
Topics: Anemia, Aplastic; Anemia, Refractory; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 7; Cyclosporine; Granulocyte Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Infant; Karyotyping; Male; Translocation, Genetic | 1998 |
[Diagnosis and therapy of aplastic anemia].
Topics: Anemia, Aplastic; Blood Transfusion; Bone Marrow Transplantation; Cyclosporine; Diagnosis, Differential; Humans; Immunosuppressive Agents; Prognosis; Severity of Illness Index | 1999 |
Possible cyclosporin-danazol interaction in a patient with aplastic anaemia.
Topics: Adult; Anemia, Aplastic; Cyclosporine; Cytochrome P-450 Enzyme Inhibitors; Danazol; Drug Monitoring; Drug Synergism; Drug Therapy, Combination; Enzyme Inhibitors; Humans; Immunosuppressive Agents; Inactivation, Metabolic; Male | 1999 |
Immunosuppressive treatment of aplastic anemia with antithymocyte globulin and cyclosporine.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Growth Substances; Humans; Immunosuppressive Agents; Recurrence; Treatment Outcome | 2000 |
Ticlopidine-induced aplastic anemia: development of chromosomal abnormalities and response to immunosuppressive therapy.
Topics: Aged; Aged, 80 and over; Anemia, Aplastic; Bone Marrow; Chromosome Aberrations; Chromosome Disorders; Cyclosporine; Dexamethasone; Fibrinolytic Agents; Humans; Immunosuppressive Agents; Male; Platelet Aggregation Inhibitors; Ticlopidine; Treatment Outcome | 2000 |
Results of immunosuppression in aplastic anaemia.
Topics: Aged; Aging; Anemia, Aplastic; Antilymphocyte Serum; Child; Cyclosporine; Granulocyte Colony-Stimulating Factor; Humans; Immunosuppression Therapy; Immunosuppressive Agents | 2000 |
[Efficacy of cyclosporin A in the treatment of aplastic anemia and its mechanism].
Topics: Anemia, Aplastic; CD4-CD8 Ratio; Cyclosporine; Humans | 1998 |
Bone marrow aplasia after pipobroman: an immune-mediated mechanism?
Topics: Aged; Aged, 80 and over; Anemia, Aplastic; Antineoplastic Agents, Alkylating; Chronic Disease; Cyclosporine; Female; Humans; Immunosuppressive Agents; Middle Aged; Pipobroman; Thrombocythemia, Essential | 2001 |
Acute necrotizing gastritis by Escherichia coli in a severely neutropenic patient.
Topics: Acute Disease; Amikacin; Anemia, Aplastic; Antilymphocyte Serum; Combined Modality Therapy; Cyclosporine; Drug Therapy, Combination; Escherichia coli Infections; Gastric Mucosa; Gastritis; Granulocyte Colony-Stimulating Factor; Immunosuppressive Agents; Meropenem; Methylprednisolone; Necrosis; Neutropenia; Omeprazole; Parenteral Nutrition, Total; T-Lymphocytes; Thienamycins | 2002 |
Aplastic anaemia: pathogenetic mechanisms and treatment with special reference to immunomodulation.
Topics: Adult; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Transplantation; Cyclosporine; Humans; Immunosuppression Therapy; Immunotherapy; Middle Aged; T-Lymphocytes; Treatment Outcome | 1992 |
[Progress in biology and therapy of aplastic anemia and other conditions of bone marrow failure].
Topics: Adult; Agranulocytosis; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow; Bone Marrow Transplantation; Child; Cyclosporine; Fanconi Anemia; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Methylprednisolone; Thrombocytopenia | 1992 |
Allogeneic bone marrow transplantation for severe aplastic anemia.
Topics: Adolescent; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Child; Child, Preschool; Cyclosporine; Female; Graft vs Host Disease; Humans; Male; Methotrexate; Survival Analysis; Transplantation, Homologous | 1991 |
Recent treatments of aplastic anemia. The International Group on SAA.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Transplantation; Cyclosporine; Drug Therapy, Combination; Growth Substances; Humans; Prednisone; Tissue Donors | 1991 |
90 trial(s) available for cyclosporine and Anemia, Aplastic
| Article | Year |
|---|---|
Long-term outcomes in patients with severe aplastic anemia treated with immunosuppression and eltrombopag: a phase 2 study.
Topics: Adult; Anemia, Aplastic; Benzoates; Cyclosporine; Female; Humans; Hydrazines; Immunosuppressive Agents; Male; Middle Aged; Prospective Studies; Pyrazoles; Survival Analysis; Treatment Outcome; Young Adult | 2022 |
Eltrombopag Added to Immunosuppression in Severe Aplastic Anemia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia, Aplastic; Antilymphocyte Serum; Benzoates; Cyclosporine; Drug Therapy, Combination; Female; Humans; Hydrazines; Immunosuppression Therapy; Immunosuppressive Agents; Male; Middle Aged; Progression-Free Survival; Prospective Studies; Pyrazoles; Receptors, Thrombopoietin; Remission Induction; Young Adult | 2022 |
Alemtuzumab in relapsed immune severe aplastic anemia: Long-term results of a phase II study.
Topics: Adult; Alemtuzumab; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Female; Humans; Immunosuppressive Agents; Male; Recurrence; Treatment Outcome | 2023 |
Long-term outcome of a randomized controlled study in patients with newly diagnosed severe aplastic anemia treated with antithymocyte globulin and cyclosporine, with or without granulocyte colony-stimulating factor: a Severe Aplastic Anemia Working Party
Topics: Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow; Cyclosporine; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Granulocytes; Humans; Immunosuppressive Agents; Prospective Studies | 2020 |
Longitudinal evaluation of eltrombopag in paediatric acquired severe aplastic anaemia.
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Benzoates; Child; Child, Preschool; Cyclosporine; Female; Follow-Up Studies; Humans; Hydrazines; Immunosuppressive Agents; Male; Off-Label Use; Pyrazoles; Receptors, Thrombopoietin; Treatment Outcome | 2020 |
Long-term follow-up of a novel immunosuppressive strategy of cyclosporine alternatively combined with levamisole for severe aplastic anemia.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Child; Child, Preschool; Cyclosporine; Developing Countries; Disease-Free Survival; Female; Follow-Up Studies; Humans; Immunosuppression Therapy; Levamisole; Male; Middle Aged; Severity of Illness Index; Survival Rate | 2020 |
Eltrombopag in Combination with Rabbit Anti-thymocyte Globulin/Cyclosporine A in Immunosuppressive Therapy-naïve Patients with Aplastic Anemia in Japan.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Benzoates; Cyclosporine; Humans; Hydrazines; Immunosuppressive Agents; Japan; Neoplasm Recurrence, Local; Pyrazoles; Treatment Outcome | 2021 |
Eltrombopag added to immunosuppression for children with treatment-naïve severe aplastic anaemia.
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Benzoates; Child; Cyclosporine; Female; Humans; Hydrazines; Immunosuppressive Agents; Male; Pyrazoles; Treatment Outcome | 2021 |
Combination of umbilical cord mesenchymal stem cells and standard immunosuppressive regimen for pediatric patients with severe aplastic anemia.
Topics: Anemia, Aplastic; Child; Cyclosporine; Humans; Mesenchymal Stem Cells; Prospective Studies; Treatment Outcome; Umbilical Cord | 2021 |
Eltrombopag Added to Standard Immunosuppression for Aplastic Anemia.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antigens, CD34; Antilymphocyte Serum; Benzoates; Cell Count; Cyclosporine; Drug Therapy, Combination; Female; Hematologic Agents; Humans; Hydrazines; Immunosuppression Therapy; Immunosuppressive Agents; Male; Middle Aged; Prospective Studies; Pyrazoles; Receptors, Thrombopoietin; Young Adult | 2017 |
Regulatory T cells and CD20
Topics: Adolescent; Anemia, Aplastic; Antigens, CD20; Antilymphocyte Serum; B-Lymphocytes; Biomarkers; Child; Child, Preschool; Cyclosporine; Female; Follow-Up Studies; Humans; Immunoglobulins, Intravenous; Infant; Male; Severity of Illness Index; T-Lymphocytes, Regulatory | 2018 |
Outcomes of optimized over standard protocol of rabbit antithymocyte globulin for severe aplastic anemia: a single-center experience.
Topics: Adolescent; Adult; Anemia, Aplastic; Animals; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Disease-Free Survival; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Male; Middle Aged; Rabbits; Retrospective Studies; Survival Rate | 2013 |
Cyclosporin combined with levamisole for refractory or relapsed severe aplastic anaemia.
Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Child; Cyclosporine; Drug Resistance; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Immunologic Factors; Immunosuppressive Agents; Levamisole; Male; Middle Aged; Remission Induction; Salvage Therapy; T-Lymphocytes; Young Adult | 2013 |
Efficacy of glycyrrhizin combined with cyclosporine in the treatment of non-severe aplastic anemia.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Cyclosporine; Drug Therapy, Combination; Female; Glycyrrhizic Acid; Humans; Interferon-gamma; Interleukin-2; Male; Middle Aged | 2013 |
Rapid donor T-cell engraftment increases the risk of chronic graft-versus-host disease following salvage allogeneic peripheral blood hematopoietic cell transplantation for bone marrow failure syndromes.
Topics: Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Antineoplastic Agents; Bone Marrow Diseases; Bone Marrow Failure Disorders; Child; Chronic Disease; Cyclosporine; Female; Graft Rejection; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Hemoglobinuria, Paroxysmal; Humans; Immunosuppressive Agents; Male; Middle Aged; Mycophenolic Acid; Peripheral Blood Stem Cell Transplantation; Risk Factors; Salvage Therapy; T-Lymphocytes; Time Factors; Transplantation Conditioning; Transplantation, Homologous; Vidarabine; Young Adult | 2013 |
Horse antithymocyte globulin as salvage therapy after rabbit antithymocyte globulin for severe aplastic anemia.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cohort Studies; Cross-Over Studies; Cyclophosphamide; Cyclosporine; Female; Humans; Male; Middle Aged; Salvage Therapy; Survival Analysis; Treatment Outcome; Young Adult | 2014 |
Evaluation of treatment responses and colony-forming progenitor cells in 50 patients with aplastic anemia after immunosuppressive therapy or hematopoietic stem cell transplantation: a single-center experience.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Combined Modality Therapy; Cyclosporine; Drug Therapy, Combination; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Male; Middle Aged; Stem Cells; Survival Rate; Treatment Outcome; Young Adult | 2014 |
Prolonged cyclosporine administration after antithymocyte globulin delays but does not prevent relapse in severe aplastic anemia.
Topics: Adult; Anemia, Aplastic; Antilymphocyte Serum; Biomarkers; Cyclosporine; Female; Humans; Male; Treatment Outcome | 2014 |
Frontline therapy of severe aplastic anaemia with fludarabine, cyclophosphamide and ciclosporin.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Cyclophosphamide; Cyclosporine; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Vidarabine | 2015 |
[Effect of Compound Zaofan Pill on Bone Marrow MVD and VEGF of Patients with Chronic Aplastic Anemia].
Topics: Anemia, Aplastic; Bone Marrow; Cyclosporine; Humans; Vascular Endothelial Growth Factor A | 2015 |
Comparison of long-term outcomes between children with aplastic anemia and refractory cytopenia of childhood who received immunosuppressive therapy with antithymocyte globulin and cyclosporine.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Chromosome Deletion; Chromosome Disorders; Chromosomes, Human, Pair 7; Cyclosporine; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Infant; Leukemia, Myeloid, Acute; Male; Myelodysplastic Syndromes; Prospective Studies | 2015 |
Intravenous infusion of allogeneic mesenchymal stromal cells in refractory or relapsed aplastic anemia.
Topics: Adult; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Female; Humans; Immunologic Factors; Immunosuppression Therapy; Immunosuppressive Agents; In Situ Hybridization, Fluorescence; Infusions, Intravenous; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Middle Aged; Transplantation, Homologous; Treatment Outcome; Young Adult | 2015 |
[Severe acquired aplastic anemia: historical outcome of patients treated by allogeneic bone marrow transplantation from matched sibling donors. A study by the Spanish Group for Bone Marrow Transplantation in Children (GETMON)].
Topics: Anemia, Aplastic; Antineoplastic Agents; Bone Marrow Transplantation; Child; Cyclosporine; Female; Graft Rejection; Humans; Immunosuppressive Agents; Male; Severity of Illness Index; Siblings; Spain; Tissue Donors; Transplantation, Homologous | 2008 |
A pilot dose-escalating study of alemtuzumab plus cyclosporine for patients with bone marrow failure syndrome.
Topics: Adolescent; Adult; Aged; Alemtuzumab; Anemia, Aplastic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Bone Marrow Diseases; Cyclosporine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myelodysplastic Syndromes; Pilot Projects; Red-Cell Aplasia, Pure; Survival Rate; Treatment Outcome; Young Adult | 2009 |
Tacrolimus as an alternative to cyclosporine in the maintenance phase of immunosuppressive therapy for severe aplastic anemia in children.
Topics: Adolescent; Anemia, Aplastic; Child; Child, Preschool; Cyclosporine; Disease-Free Survival; Humans; Immunosuppressive Agents; Tacrolimus; Treatment Outcome; Young Adult | 2009 |
Treatment of severe aplastic anemia with a combination of horse antithymocyte globulin and cyclosporine, with or without sirolimus: a prospective randomized study.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Animals; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Drug Therapy, Combination; Female; Horses; Humans; Immunosuppressive Agents; Kaplan-Meier Estimate; Male; Middle Aged; Proportional Hazards Models; Prospective Studies; Recurrence; Sirolimus; Treatment Outcome; Young Adult | 2009 |
Phase II study of rabbit anti-thymocyte globulin, cyclosporine and granulocyte colony-stimulating factor in patients with aplastic anemia and myelodysplastic syndrome.
Topics: Adult; Aged; Aged, 80 and over; Anemia, Aplastic; Animals; Antilymphocyte Serum; Cyclosporine; Granulocyte Colony-Stimulating Factor; Humans; Middle Aged; Myelodysplastic Syndromes; Rabbits | 2009 |
[Efficacy of immunosuppressive therapy in children with acquired aplastic anemia].
Topics: Adolescent; Anemia, Aplastic; Child; Child, Preschool; Cyclosporine; Female; Humans; Immunoglobulins, Intravenous; Immunosuppression Therapy; Immunosuppressive Agents; Infant; Male; Retrospective Studies; Treatment Outcome | 2009 |
Subcutaneous alemtuzumab plus cyclosporine for the treatment of aplastic anemia.
Topics: Adolescent; Adult; Aged; Alemtuzumab; Anemia, Aplastic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Child; Cyclosporine; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Male; Middle Aged; Remission Induction; Survival Analysis; Treatment Outcome; Young Adult | 2010 |
Alemtuzumab is safe and effective as immunosuppressive treatment for aplastic anaemia and single-lineage marrow failure: a pilot study and a survey from the EBMT WPSAA.
Topics: Adult; Aged; Aged, 80 and over; Alemtuzumab; Anemia, Aplastic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Cyclosporine; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Injections, Subcutaneous; Male; Middle Aged; Pilot Projects; Prospective Studies | 2010 |
[Transplantation of the bone marrow from a HLA-compatible unrelated donor after immunoablative conditioning in children with acquired aplastic anemia unresponsive to combined immunosuppressive therapy: preliminary results].
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cyclosporine; Disease-Free Survival; Graft Survival; Graft vs Host Reaction; HLA Antigens; Humans; Immunosuppressive Agents; Tissue Donors; Transplantation Conditioning; Treatment Failure | 2010 |
[The use of allogeneic bone marrow transplantation and immunosuppressive therapy in the treatment of patients with acquired aplastic anemia].
Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Transplantation; Child; Child, Preschool; Cyclosporine; Disease-Free Survival; Drug Therapy, Combination; Female; HLA Antigens; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Male; Middle Aged; Severity of Illness Index; Tissue Donors; Transplantation, Homologous; Young Adult | 2010 |
Impact of cytokine gene polymorphisms on risk and treatment outcomes of aplastic anemia.
Topics: Adult; Alleles; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Female; Genes, Dominant; Genetic Association Studies; Genetic Predisposition to Disease; Haplotypes; Humans; Immunosuppressive Agents; Interferon-gamma; Male; Middle Aged; Models, Genetic; Polymorphism, Single Nucleotide; Republic of Korea; Risk Factors; Transforming Growth Factor beta1 | 2011 |
A randomized controlled study in patients with newly diagnosed severe aplastic anemia receiving antithymocyte globulin (ATG), cyclosporine, with or without G-CSF: a study of the SAA Working Party of the European Group for Blood and Marrow Transplantation.
Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Disease-Free Survival; Drug Therapy, Combination; Female; Granulocyte Colony-Stimulating Factor; Hospitalization; Humans; Immunosuppressive Agents; Male; Middle Aged; Severity of Illness Index; Survival Analysis; Young Adult | 2011 |
Allogeneic hematopoietic stem cell transplantation for childhood aplastic anemia: prospective trial in China.
Topics: Adolescent; Anemia, Aplastic; Bone Marrow Transplantation; Cell Survival; Child; Child, Preschool; China; Combined Modality Therapy; Cyclosporine; Female; Filgrastim; Follow-Up Studies; Graft Survival; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Histocompatibility Testing; Humans; Immunosuppressive Agents; Living Donors; Male; Methotrexate; Myeloablative Agonists; Peripheral Blood Stem Cell Transplantation; Recombinant Proteins; Siblings; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome | 2011 |
Efficacy of rabbit anti-thymocyte globulin in severe aplastic anemia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia, Aplastic; Animals; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Cytokines; Female; Horses; Humans; Immunosuppressive Agents; Male; Middle Aged; Polymorphism, Genetic; Rabbits; Recurrence; Survival Analysis; Treatment Outcome; Young Adult | 2011 |
Activity of alemtuzumab monotherapy in treatment-naive, relapsed, and refractory severe acquired aplastic anemia.
Topics: Adolescent; Adult; Aged; Alemtuzumab; Anemia, Aplastic; Animals; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antilymphocyte Serum; Antineoplastic Agents; Child; Child, Preschool; Cyclosporine; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prospective Studies; Rabbits; Salvage Therapy; Survival Rate; Treatment Outcome; Young Adult | 2012 |
Final results of the phase II study of rabbit anti-thymocyte globulin, ciclosporin, methylprednisone, and granulocyte colony-stimulating factor in patients with aplastic anaemia and myelodysplastic syndrome.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Drug Administration Schedule; Drug Therapy, Combination; Female; Glucocorticoids; Granulocyte Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Male; Methylprednisolone; Middle Aged; Myelodysplastic Syndromes; Survival Analysis; Treatment Outcome; Young Adult | 2012 |
Prospective study of rabbit antithymocyte globulin and cyclosporine for aplastic anemia from the EBMT Severe Aplastic Anaemia Working Party.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Animals; Antilymphocyte Serum; CD4-Positive T-Lymphocytes; Cyclosporine; Drug Therapy, Combination; Europe; Female; Horses; Humans; Immunosuppressive Agents; Male; Middle Aged; Pilot Projects; Prospective Studies; Rabbits; Survival Analysis; Young Adult | 2012 |
Improved outcome of adults with aplastic anaemia treated with arsenic trioxide plus ciclosporin.
Topics: Adipogenesis; Adult; Anemia, Aplastic; Arsenic Trioxide; Arsenicals; Blood Cell Count; Blood Transfusion; Bone Marrow; Combined Modality Therapy; Cyclosporine; Drug Therapy, Combination; Female; Humans; Male; Mesenchymal Stem Cells; Oxides; Remission Induction; Treatment Outcome; Young Adult | 2013 |
High-dose cyclophosphamide compared with antithymocyte globulin for treatment of acquired severe aplastic anemia.
Topics: Adolescent; Adult; Alopecia; Anemia, Aplastic; Antilymphocyte Serum; Cyclophosphamide; Cyclosporine; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Fever; Health Care Costs; Humans; Immunosuppressive Agents; Male; Middle Aged; Nausea; Outcome Assessment, Health Care; Remission Induction; Severity of Illness Index; Survival Rate; Time Factors; Young Adult | 2013 |
Antithymocyte globulin with or without cyclosporin A: 11-year follow-up of a randomized trial comparing treatments of aplastic anemia.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Blood Cell Count; Cyclosporine; Disease-Free Survival; Drug Therapy, Combination; Follow-Up Studies; Hemoglobinuria, Paroxysmal; Humans; Immunosuppressive Agents; Kinetics; Leukemia; Methylprednisolone; Myelodysplastic Syndromes; Neoplasms; Recurrence; Remission Induction; Salvage Therapy; Survival Rate | 2003 |
Long-term follow-up of allogeneic stem cell transplantation in patients with severe aplastic anemia after conditioning with cyclophosphamide plus antithymocyte globulin.
Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Cyclophosphamide; Cyclosporine; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Longitudinal Studies; Male; Methotrexate; Mycoses; Survival Analysis; Transplantation Conditioning; Transplantation, Homologous | 2002 |
Antithymocyte globulin and cyclosporine for severe aplastic anemia: association between hematologic response and long-term outcome.
Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Blood Cell Count; Child; Child, Preschool; Cyclosporine; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Male; Methylprednisolone; Recurrence; Survival Analysis; T-Lymphocytes; Treatment Outcome | 2003 |
Outcome of adult severe or very severe aplastic anemia treated with immunosuppressive therapy compared with bone marrow transplantation: multicenter trial.
Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Transplantation; Cyclosporine; Female; Humans; Immunosuppressive Agents; Male; Multivariate Analysis; Prognosis; Recurrence; Severity of Illness Index; Survival Rate; Treatment Outcome | 2003 |
Long-term results of the immunosuppressive treatment of patients with severe acquired aplastic anemia: a single institution study.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Female; Humans; Immunosuppressive Agents; Male; Middle Aged | 2003 |
Treatment of severe aplastic anemia with antilymphocyte globulin, cyclosporine and two different granulocyte colony-stimulating factor regimens: a GITMO prospective randomized study.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Animals; Antilymphocyte Serum; Blood Cell Count; Child; Child, Preschool; Cyclosporine; Disease-Free Survival; Drug Administration Schedule; Drug Therapy, Combination; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Horses; Humans; Immunosuppressive Agents; Life Tables; Male; Methylprednisolone; Middle Aged; Prospective Studies; Survival Analysis; Treatment Failure; Treatment Outcome | 2004 |
[Clinical efficacy and T-lymphocyte subset, serum interferon-gamma (IFN-gamma), tumor necrosis factor-alpha (TNF-alpha), interleukin-2(IL-2) levels on treatment of chronic aplastic anemia patients by shenfu injection combined with stanozol and cyclosporin
Topics: Aconitine; Adolescent; Adult; Aged; Anemia, Aplastic; CD4-CD8 Ratio; Cyclosporine; Drug Combinations; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Ginsenosides; Humans; Interferon-gamma; Interleukin-2; Kidney Diseases; Male; Medicine, Chinese Traditional; Middle Aged; Phytotherapy; Stanozolol; Tumor Necrosis Factor-alpha; Yang Deficiency | 2005 |
Immunosuppressive therapy for aplastic anemia in children: a more severe disease predicts better survival.
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Female; Granulocyte Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Infant; Leukocyte Count; Male; Neutrophils; Prognosis; Survival Rate; Treatment Outcome | 2005 |
Re: Twenty-year follow-up in patients with aplastic anemia given marrow grafts from HLA-identical siblings and randomized to receive methotrexate/cyclosporine or methotrexate alone for prevention of graft-versus-host disease.
Topics: Anemia, Aplastic; Bone Marrow Transplantation; Cyclosporine; Female; Follow-Up Studies; Graft vs Host Disease; Humans; Immunosuppressive Agents; Male; Methotrexate | 2005 |
[A clinical trial of anti-CD4 CD8 monoclonal antibodies combined with cyclosporine A in treatment of severe aplastic anemia].
Topics: Adolescent; Adult; Anemia, Aplastic; Antibodies, Monoclonal; CD4 Antigens; CD8 Antigens; Child; Combined Modality Therapy; Cyclosporine; Female; Humans; Immunosuppressive Agents; Male; Middle Aged; Treatment Outcome | 2005 |
Treatment of severe aplastic anaemia with combined immunosuppression: anti-thymocyte globulin, ciclosporin and mycophenolate mofetil.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Combined Modality Therapy; Cyclosporine; Disease Progression; Drug Therapy, Combination; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Male; Middle Aged; Mycophenolic Acid; Myelodysplastic Syndromes; Recurrence; Survival Analysis; Treatment Outcome | 2006 |
Assessment of converting from intravenous to oral administration of cyclosporin A in pediatric allogeneic hematopoietic stem cell transplant recipients.
Topics: Administration, Oral; Adolescent; Age Factors; Anemia, Aplastic; Biological Availability; Body Weight; Child; Child, Preschool; Cyclosporine; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Infant; Infusions, Intravenous; Leukemia; Male; Metabolic Clearance Rate; Time Factors; Treatment Outcome | 2006 |
Identification of novel regulators in T-cell differentiation of aplastic anemia patients.
Topics: Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Cells; CD3 Complex; Cell Differentiation; Cluster Analysis; Cyclosporine; Female; Humans; Immunosuppressive Agents; Immunotherapy; Male; Middle Aged; Oligonucleotide Array Sequence Analysis; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; T-Lymphocytes | 2006 |
Distinct EBV and CMV reactivation patterns following antibody-based immunosuppressive regimens in patients with severe aplastic anemia.
Topics: Adolescent; Adult; Aged; Alemtuzumab; Anemia, Aplastic; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antilymphocyte Serum; Antineoplastic Agents; Child; Child, Preschool; Cyclosporine; Cytomegalovirus; Cytomegalovirus Infections; DNA, Viral; Epstein-Barr Virus Infections; Female; Herpesvirus 4, Human; Horses; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Male; Middle Aged; Monitoring, Physiologic; Polymerase Chain Reaction; Rabbits; Sirolimus; Time Factors; Virus Activation | 2007 |
[Immunosuppressive therapy for 54 children patients with acquired severe aplastic anemia].
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Female; Humans; Immunosuppressive Agents; Male | 2006 |
Treatment of acquired severe aplastic anemia with antilymphocyte globulin, cyclosporin A, methyprednisolone, and granulocyte colony-stimulating factor.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Animals; Antilymphocyte Serum; Cyclosporine; Female; Glucocorticoids; Granulocyte-Macrophage Colony-Stimulating Factor; Horses; Humans; Immunosuppressive Agents; Male; Methylprednisolone; Middle Aged; Neutrophils; Recurrence; Survival Analysis; Time Factors; Treatment Outcome | 2007 |
Treatment of severe aplastic anemia with antithymocyte globulin and cyclosporin A with or without G-CSF in adults: a multicenter randomized study in Japan.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Drug Therapy, Combination; Female; Granulocyte Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Japan; Male; Middle Aged; Survival Rate; Treatment Outcome | 2007 |
Antithymocyte globulin and cyclosporine for treatment of 44 children with hepatitis associated aplastic anemia.
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Transplantation; Child; Child, Preschool; Cyclosporine; Disease-Free Survival; Female; Follow-Up Studies; Hepatitis; Histocompatibility Testing; Humans; Immunosuppressive Agents; Infant; Male; Survival Rate; Transplantation, Homologous | 2007 |
Antilymphocyte globulin, cyclosporin, and granulocyte colony-stimulating factor in patients with acquired severe aplastic anemia (SAA): a pilot study of the EBMT SAA Working Party.
Topics: Actuarial Analysis; Adolescent; Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Blood Transfusion; Child; Child, Preschool; Combined Modality Therapy; Cyclosporine; Feasibility Studies; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukapheresis; Male; Middle Aged; Neutropenia; Neutrophils; Pilot Projects; Prednisolone; Recombinant Proteins; Survival Analysis; Treatment Outcome | 1995 |
Cyclophosphamide/antithymocyte globulin conditioning of patients with severe aplastic anemia for marrow transplantation from HLA-matched siblings: preliminary results.
Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Aspergillosis; Bone Marrow Transplantation; Child; Cyclophosphamide; Cyclosporine; Female; Fungemia; Graft vs Host Disease; Histocompatibility; HLA Antigens; Humans; Male; Methotrexate; Polymorphism, Restriction Fragment Length | 1995 |
Long-term granulocyte-macrophage colony-stimulating factor and immunosuppression in the treatment of acquired severe aplastic anemia.
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Drug Administration Schedule; Drug Therapy, Combination; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Infant; Male; Prednisone | 1995 |
Intensive immunosuppression with antithymocyte globulin and cyclosporine as treatment for severe acquired aplastic anemia.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Disease-Free Survival; Female; Hemoglobinuria, Paroxysmal; Humans; Leukemia, Myeloid, Acute; Life Tables; Male; Middle Aged; Prognosis; Salvage Therapy; Survival Rate; T-Lymphocytes; Treatment Outcome | 1995 |
[Clinical study of ciclosporin in patients with aplastic anemia and pure red-cell aplasia].
Topics: Adult; Aged; Anemia, Aplastic; Cyclosporine; Female; Humans; Male; Middle Aged; Red-Cell Aplasia, Pure | 1995 |
The effect of cyclosporine on haematological parameters in patients with paroxysmal nocturnal haemoglobinuria.
Topics: Adult; Aged; Anemia, Aplastic; Antigens, CD; Blood Cell Count; Cyclosporine; Female; Glycosylphosphatidylinositols; Hemoglobins; Hemoglobinuria, Paroxysmal; Hemolysis; Humans; Male; Neutrophils; Syndrome | 1995 |
T cell depletion by exposure to Campath-1G in vitro prevents graft-versus-host disease.
Topics: Adolescent; Adult; Alemtuzumab; Anemia, Aplastic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Bone Marrow Transplantation; Child; Cyclosporine; Female; Graft vs Host Disease; Humans; Immunosuppressive Agents; Leukemia; Lymphocyte Depletion; Male; Middle Aged; Multiple Myeloma; Transplantation, Homologous | 1994 |
Treatment of aplastic anemia with an investigational antilymphocyte serum prepared in rabbits.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Animals; Antilymphocyte Serum; Combined Modality Therapy; Cyclosporine; Female; Horses; Humans; Male; Middle Aged; Rabbits; Survival Rate; Time Factors | 1994 |
Topical cyclosporin A for treatment of oral chronic graft-versus-host disease.
Topics: Administration, Topical; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Cyclosporine; Female; Graft vs Host Disease; Humans; Leukemia; Male; Middle Aged; Mouth Diseases; Mouthwashes; Myelodysplastic Syndromes | 1994 |
Antithymocyte globulin, cyclosporine, and prednisone for the treatment of severe aplastic anemia in children. A pilot study.
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Female; Humans; Male; Pilot Projects; Prednisone | 1994 |
Long-term follow-up of a randomized trial of graft-versus-host disease prevention by methotrexate/cyclosporine versus methotrexate alone in patients given marrow grafts for severe aplastic anemia.
Topics: Anemia, Aplastic; Bone Marrow Transplantation; Cyclosporine; Graft vs Host Disease; Humans; Methotrexate; Prospective Studies | 1994 |
Complete remission in severe aplastic anemia after high-dose cyclophosphamide without bone marrow transplantation.
Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Anemia, Aplastic; Bone Marrow; Child; Cyclophosphamide; Cyclosporine; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Male; Regeneration; Remission Induction; Treatment Outcome | 1996 |
Treatment results of 23 cases of severe aplastic anemia with lymphocytapheresis.
Topics: Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Autoimmune Diseases; Cerebral Hemorrhage; Combined Modality Therapy; Cyclosporine; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoiesis; Humans; Immunosuppressive Agents; Leukapheresis; Life Tables; Lymphocyte Depletion; Male; Middle Aged; Oxymetholone; Remission Induction; Survival Analysis; T-Lymphocyte Subsets; Treatment Outcome | 1997 |
Long-term interleukin-3 and intensive immunosuppression in the treatment of aplastic anemia.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Colony-Forming Units Assay; Cyclosporine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Immunosuppression Therapy; Interleukin-3; Leukocyte Count; Male; Middle Aged; Neutrophils; Patient Selection; Platelet Count; Recombinant Proteins; Reticulocyte Count; Time Factors | 1996 |
Prospective randomized multicenter study comparing cyclosporin alone versus the combination of antithymocyte globulin and cyclosporin for treatment of patients with nonsevere aplastic anemia: a report from the European Blood and Marrow Transplant (EBMT) S
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia, Aplastic; Antilymphocyte Serum; Blood Transfusion; Combined Modality Therapy; Cyclosporine; Drug Therapy, Combination; Europe; Female; Hemoglobins; Humans; Immunoglobulins; Immunosuppressive Agents; Life Tables; Male; Middle Aged; Platelet Count; Prospective Studies; Survival Analysis; Survival Rate; T-Lymphocytes; Treatment Outcome | 1999 |
Rabbit antithymocyte globulin (r-ATG) plus cyclosporine and granulocyte colony stimulating factor is an effective treatment for aplastic anaemia patients unresponsive to a first course of intensive immunosuppressive therapy. Gruppo Italiano Trapianto di M
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Animals; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Drug Therapy, Combination; Female; Granulocyte Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Infant; Male; Middle Aged; Rabbits; Survival Rate; Treatment Failure; Treatment Outcome | 1999 |
Cyclosporin A monotherapy in young Indian aplastic anaemia patients.
Topics: Adolescent; Adult; Anemia, Aplastic; Child; Cyclosporine; Female; Humans; Immunosuppressive Agents; India; Male; Prospective Studies | 1999 |
Antilymphocyte globulin, cyclosporine, prednisolone, and granulocyte colony-stimulating factor for severe aplastic anemia: an update of the GITMO/EBMT study on 100 patients. European Group for Blood and Marrow Transplantation (EBMT) Working Party on Sever
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Drug Therapy, Combination; Female; Glucocorticoids; Glycosylphosphatidylinositols; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Infant; Male; Middle Aged; Prednisolone; Recurrence; Time Factors | 2000 |
Cyclosporin A and short-term methotrexate versus cyclosporin A as graft versus host disease prophylaxis in patients with severe aplastic anemia given allogeneic bone marrow transplantation from an HLA-identical sibling: results of a GITMO/EBMT randomized
Topics: Adolescent; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Child; Child, Preschool; Cyclosporine; Drug Therapy, Combination; Female; Follow-Up Studies; Graft Rejection; Graft vs Host Disease; Histocompatibility Testing; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Nuclear Family; Survival Analysis; Time Factors; Transplantation, Homologous; Treatment Outcome | 2000 |
Immunosuppressive therapy using antithymocyte globulin, cyclosporine, and danazol with or without human granulocyte colony-stimulating factor in children with acquired aplastic anemia.
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Danazol; Drug Therapy, Combination; Estrogen Antagonists; Female; Granulocyte Colony-Stimulating Factor; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Infant; Male; Treatment Outcome | 2000 |
High-dose cyclophosphamide in severe aplastic anaemia: a randomised trial.
Topics: Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Cyclophosphamide; Cyclosporine; Drug Administration Schedule; Humans; Immunosuppressive Agents; Infusions, Intravenous; Middle Aged; Mycoses; Risk Factors | 2000 |
Treatment of aplastic anaemia with granulocyte-colony stimulating factor and risk of malignancy. Italian Aplastic Anaemia Study Group.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Drug Therapy, Combination; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Hemoglobinuria, Paroxysmal; Humans; Immunosuppressive Agents; Infant; Leukemia; Male; Middle Aged; Mouth Neoplasms; Myelodysplastic Syndromes; Neoplasms; Risk Factors; Survival Analysis; Treatment Outcome | 2001 |
A multicenter, randomized, double-blind comparison of different doses of intravenous immunoglobulin for prevention of graft-versus-host disease and infection after allogeneic bone marrow transplantation.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Child; Child, Preschool; Cyclosporine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Graft vs Host Disease; Histocompatibility Testing; Humans; Immunoglobulins, Intravenous; Immunosuppression Therapy; Infections; Leukemia; Lymphocyte Depletion; Lymphoma; Male; Methotrexate; Middle Aged; Survival Analysis; Time Factors; Tissue Donors; Transplantation, Homologous | 2001 |
[Antilymphocyte globulin combining with cyclosporine A in the treatment of severe aplastic anemia].
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Combined Modality Therapy; Cyclosporine; Female; Humans; Immunosuppressive Agents; Male; Middle Aged; Prospective Studies | 1999 |
Low dose cyclosporine-a therapy in severe aplastic anaemia.
Topics: Administration, Oral; Adult; Anabolic Agents; Anemia, Aplastic; Child; Cyclosporine; Female; Humans; Immunosuppressive Agents; Male; Prognosis; Stanozolol; Time Factors | 2001 |
[The combination of cyclosporin A and androgen in the treatment of chronic aplastic anemia].
Topics: Adolescent; Adult; Aged; Androgens; Anemia, Aplastic; Blood Cell Count; Child; Chronic Disease; Cyclosporine; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Treatment Outcome; Young Adult | 2001 |
[Sequential intensified immunosuppressive therapy combining with hematopoietic growth factors in the treatment of severe aplastic anemia].
Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Drug Therapy, Combination; Female; Hematopoietic Cell Growth Factors; Humans; Immunosuppressive Agents; Male; Middle Aged; Prospective Studies; Treatment Outcome; Young Adult | 2001 |
[Apoptosis of bone marrow cells aplastic anemia patients treated with cyclosporin A].
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Apoptosis; Bone Marrow Cells; Child; Cyclosporine; Female; Humans; Male; Middle Aged; Treatment Outcome; Young Adult | 2001 |
Optimization of recombinant human erythropoietin therapy after allogeneic hematopoietic stem cell transplantation.
Topics: Adolescent; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Child; Cyclosporine; Drug Administration Schedule; Erythropoietin; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Leukemia; Lymphoma, Non-Hodgkin; Male; Middle Aged; Myelodysplastic Syndromes; Recombinant Proteins; Thrombocytosis; Transplantation, Homologous | 2002 |
A multicenter randomized study comparing cyclosporin-A alone and antithymocyte globulin with prednisone for treatment of severe aplastic anemia. The cooperative group on the treatment of aplastic anemia.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Drug Therapy, Combination; Humans; Multivariate Analysis; Prednisone; Survival Analysis; Treatment Outcome | 1992 |
Multicenter randomized study comparing cyclosporine-A alone and antithymocyte globulin with prednisone for treatment of severe aplastic anemia.
Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Female; Follow-Up Studies; Humans; Leukocyte Count; Male; Neutrophils; Prednisone; Regression Analysis | 1992 |
428 other study(ies) available for cyclosporine and Anemia, Aplastic
| Article | Year |
|---|---|
[Diagnosis and treatment for aplastic anemia].
Topics: Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans | 2021 |
A case of thymoma showing significant tumor reduction after anti-thymocyte globulin.
Topics: Aged; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Female; Humans; Thymoma; Thymus Neoplasms | 2022 |
[Establishment of a Mouse Model of Acquired Aplastic Anemia Mediated by Cyclophosphamide Combined with Cyclosporine].
Topics: Anemia, Aplastic; Animals; Bone Marrow; Cyclophosphamide; Cyclosporine; Female; Mice; Mice, Inbred BALB C | 2022 |
A New Immunosuppressive Therapy for Very Severe Aplastic Anemia in Children with Autoantibodies.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Autoantibodies; Child; Cyclosporine; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Prednisone; Retrospective Studies; Treatment Outcome | 2022 |
[The efficacy of eltrombopag plus cyclosporine A in patients with transfusion-dependent non-severe aplastic anemia: a retrospective study from single center].
Topics: Anemia, Aplastic; Antilymphocyte Serum; Benzoates; Cyclosporine; Humans; Hydrazines; Immunosuppressive Agents; Pyrazoles; Retrospective Studies | 2022 |
Effects of cimetidine on ciclosporin population pharmacokinetics and initial dose optimization in aplastic anemia patients.
Topics: Anemia, Aplastic; Cimetidine; Cyclosporine; Humans; Immunosuppressive Agents; Metabolic Clearance Rate | 2022 |
Eltrombopag as frontline treatment of aplastic anaemia in routine practice: implications on cost and efficacy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia, Aplastic; Antilymphocyte Serum; Benzoates; Cyclosporine; Female; Humans; Hydrazines; Immunosuppressive Agents; Male; Middle Aged; Pyrazoles; Treatment Outcome; Young Adult | 2022 |
Plasma lipidome acts as diagnostic marker and predictor for cyclosporin response in patients with aplastic anemia.
Topics: Anemia, Aplastic; Arachidonic Acid; Cyclosporine; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipidomics; Myelodysplastic Syndromes | 2023 |
Frequent HLA-DR loss on hematopoietic stem progenitor cells in patients with cyclosporine-dependent aplastic anemia carrying HLA-DR15.
Topics: Anemia, Aplastic; CD8-Positive T-Lymphocytes; Cyclosporine; Hematopoietic Stem Cells; HLA-DR Antigens; HLA-DR Serological Subtypes; Humans | 2022 |
A multicentre trial of intensive immunosuppressive therapy combined with umbilical cord blood for the treatment of severe aplastic anaemia.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Cyclophosphamide; Cyclosporine; Fetal Blood; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Treatment Outcome | 2022 |
[Correlation between Serum G-CSF Level and Immune Function in Children with Aplastic Anemia].
Topics: Anemia, Aplastic; Antilymphocyte Serum; Child; Cyclosporine; Granulocyte Colony-Stimulating Factor; Humans; Immunity; Immunosuppressive Agents | 2022 |
Severe infections and renal dysfunction during immunosuppressive therapy with cyclosporine A for aplastic anemia.
Topics: Aged; Anemia, Aplastic; Antilymphocyte Serum; Creatinine; Cyclosporine; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Kidney Diseases; Retrospective Studies; Treatment Outcome | 2022 |
A real-word experience of eltrombopag plus rabbit antithymocyte immunoglobulin-based IST in Chinese patients with severe aplastic anemia.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Benzoates; China; Cyclosporine; Humans; Hydrazines; Immunosuppression Therapy; Immunosuppressive Agents; Pyrazoles; Receptors, Thrombopoietin; Treatment Outcome | 2022 |
Hepatitis-associated Aplastic Anemia.
Topics: Anemia, Aplastic; Child; Cyclosporine; Hematopoietic Stem Cell Transplantation; Hepatitis, Autoimmune; Humans; Siblings | 2022 |
Clinical outcomes and immune responses to SARS-CoV-2 vaccination in severe aplastic anaemia.
Topics: Anemia, Aplastic; COVID-19; COVID-19 Vaccines; Cyclosporine; Humans; Immunity; Immunosuppressive Agents; Recurrence; SARS-CoV-2; Vaccination | 2022 |
First-line immunosuppressive therapy with rATG and CsA for severe aplastic anemia: 15 years' experience.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Retrospective Studies; Treatment Outcome | 2022 |
Apolipoprotein-A is a potential prognostic biomarker for severe aplastic anemia patients treated with ATG-based immunosuppressive therapy: a single-center retrospective study.
Topics: Anemia, Aplastic; Apolipoproteins; Apolipoproteins A; Biomarkers; Cholesterol, LDL; Cyclosporine; Humans; Immunoglobulin A; Immunosuppression Therapy; Immunosuppressive Agents; Lipoproteins, HDL; Middle Aged; Prognosis; Retrospective Studies; Treatment Outcome | 2022 |
Impact of antithymocyte globulin on blood cyclosporin A levels in aplastic anemia patients.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Humans; Immunosuppressive Agents; Treatment Outcome | 2023 |
Efficacy and safety of equine anti-thymocyte immunoglobulin (eATG) in three Japanese patients with moderate to very severe aplastic anemia: a case series.
Topics: Anemia, Aplastic; Animals; Antilymphocyte Serum; Cyclosporine; East Asian People; Horses; Humans; Immunosuppressive Agents; T-Lymphocytes; Treatment Outcome | 2023 |
Whole-exome sequencing identifies FANC heterozygous germline mutation as an adverse factor for immunosuppressive therapy in Chinese aplastic anemia patients aged 40 or younger: a single-center retrospective study.
Topics: Adult; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; East Asian People; Exome Sequencing; Fanconi Anemia Complementation Group Proteins; Germ-Line Mutation; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Pancytopenia; Retrospective Studies; Treatment Outcome | 2023 |
Prolonged use of eltrombopag in patients with severe aplastic anemia in the real world.
Topics: Anemia, Aplastic; Animals; Cyclosporine; Humans; Immunosuppressive Agents; Rabbits; Treatment Outcome | 2023 |
Mass cytometry analysis identifies T cell immune signature of aplastic anemia and predicts the response to cyclosporine.
Topics: Anemia, Aplastic; CD8-Positive T-Lymphocytes; CTLA-4 Antigen; Cyclosporine; Humans; Interleukin-9; T-Lymphocytes | 2023 |
[Guidelines for the diagnosis and management of aplastic anemia in China (2022)].
Topics: Anemia, Aplastic; China; Cyclosporine; Humans; Immunosuppressive Agents | 2022 |
[Avatrombopag combined with standard immunosuppressive therapy in the treatment of severe aplastic anemia with hepatic impairment in six patients].
Topics: Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Thiazoles | 2022 |
Partial SAA patients benefit from delayed response of IST.
Topics: Anemia, Aplastic; Cyclosporine; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Pancytopenia; Treatment Outcome | 2023 |
Adding cyclosporin A to eltrombopag for aplastic anemia secondary to chemotherapy for solid cancers.
Topics: Anemia, Aplastic; Benzoates; Cyclosporine; Humans; Immunosuppressive Agents; Neoplasms | 2023 |
Development and validation of early death risk score model for emergency status prediction in very severe aplastic anemia.
Topics: Adult; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Humans; Risk Factors; Treatment Outcome; Young Adult | 2023 |
Cyclosporine plus eltrombopag in the treatment of aplastic anemia with or without antithymocyte immunoglobulin: A multicenter real-world retrospective study.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Female; Humans; Immunosuppressive Agents; Retrospective Studies; Treatment Outcome | 2023 |
[Effect of Eltrombopag on Response to Immunosuppressive Therapy in Patients with Transfusion-Dependent Non-Severe Aplastic Anemia].
Topics: Anemia, Aplastic; Cyclosporine; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Retrospective Studies; Treatment Outcome | 2023 |
[Interpretiation of guidelines for the diagnosis and management of aplastic anemia in China (2022)].
Topics: Anemia, Aplastic; China; Cyclosporine; Humans; Immunosuppressive Agents | 2023 |
Real-World Costs and Cost-Effectiveness Analysis of Rabbit-Antithymocyte Globulin Versus Oxymetholone in Acquired Aplastic Anemia in Thailand.
Topics: Anemia, Aplastic; Animals; Antilymphocyte Serum; Cost-Effectiveness Analysis; Cyclosporine; Humans; Oxymetholone; Rabbits; Thailand | 2023 |
Repeated immunosuppressive rabbit antithymocyte globulin therapy for adult patients with relapsed or refractory aplastic anemia.
Topics: Adult; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Retrospective Studies; Treatment Outcome | 2023 |
Red blood cell distribution width as a prognostic factor in patients with aplastic anemia treated with cyclosporin A plus androgen or cyclosporine A alone: a retrospective study.
Topics: Androgens; Anemia, Aplastic; Cyclosporine; Erythrocytes; Humans; Prognosis; Retrospective Studies | 2023 |
[Successful treatment of eltrombopag following immunosuppressive therapy in pediatric aplastic anemia].
Topics: Adult; Anemia, Aplastic; Child; Cyclosporine; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppression Therapy | 2023 |
[Reference guide for the treatment of aplastic anemia: key points of the 2022 revision].
Topics: Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Transplantation; Cyclosporine; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Treatment Outcome; Young Adult | 2023 |
Deciphering treatment patterns in non-severe/moderate aplastic anemia: an international observational study.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Benzoates; Cyclosporine; Humans; Immunosuppressive Agents; Infant; Male; Treatment Outcome | 2023 |
[Aplastic anemia following drug-induced liver injury].
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Chemical and Drug Induced Liver Injury; Cyclosporine; Hemoglobinuria, Paroxysmal; Humans; Immunosuppressive Agents; Male | 2019 |
[Comparison of porcine antilymphocyte globulin (p-ALG) and rabbit antithymocyte globulin (r-ATG) in the treatment of children with severe aplastic anemia].
Topics: Anemia, Aplastic; Animals; Antilymphocyte Serum; Child; Cyclosporine; Humans; Immunosuppressive Agents; Swine; Treatment Outcome | 2019 |
[The Outcome of Severe Aplastic Anemia Children Treated with Reduced Dose of Cyclophosphamide Combined Cyclosporine A].
Topics: Anemia, Aplastic; Antilymphocyte Serum; Child; Cyclophosphamide; Cyclosporine; Hemoglobinuria, Paroxysmal; Humans; Immunosuppressive Agents; Treatment Outcome | 2020 |
Successful Bone Marrow Recovery After an Immunoablative Regimen With Autologous Cord Blood Transplant in a Child With Idiopathic Severe Aplastic Anemia: A Case Report.
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow; Child, Preschool; Cord Blood Stem Cell Transplantation; Cyclosporine; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Male; Methylprednisolone; Transplantation, Autologous | 2020 |
Effects of Shikonin on the Functions of Myeloid Dendritic Cells in a Mouse Model of Severe Aplastic Anemia.
Topics: Anemia, Aplastic; Animals; B7-1 Antigen; B7-2 Antigen; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cyclosporine; Dendritic Cells; Flow Cytometry; Immunosuppressive Agents; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Naphthoquinones; Pyruvate Kinase; Reverse Transcriptase Polymerase Chain Reaction | 2020 |
Severe Anaphylaxis During Allogeneic Hematopoietic Stem Cell Transplantation in a Patient with Aplastic Anemia: Case Report of Individualized Pharmaceutical Care and Literature Review.
Topics: Administration, Oral; Adult; Anaphylaxis; Anemia, Aplastic; Cyclosporine; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Infusions, Intravenous; Male; Transplantation, Homologous; Young Adult | 2020 |
Deficit of circulating CD19
Topics: Adolescent; ADP-ribosyl Cyclase 1; Adult; Aged; Anemia, Aplastic; Antigens, CD19; Antilymphocyte Serum; B-Lymphocyte Subsets; B-Lymphocytes, Regulatory; Benzoates; Bone Marrow; CD24 Antigen; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cyclosporine; Female; Humans; Hydrazines; Immunosuppressive Agents; Interleukin-10; Killer Cells, Natural; Lymphocyte Count; Lymphopenia; Male; Membrane Glycoproteins; Middle Aged; Pyrazoles; Receptors, Thrombopoietin; Young Adult | 2020 |
Immunosuppression and growth factors for severe aplastic anemia: new data for old questions.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow; Cyclosporine; Granulocytes; Humans; Immunosuppression Therapy | 2020 |
[Eltrombopag combined with cyclosporine alone for treatment of very severe aplastic anemia: a case report].
Topics: Anemia, Aplastic; Benzoates; Cyclosporine; Humans; Hydrazines; Immunosuppressive Agents; Pyrazoles | 2019 |
Single-Agent Cyclosporine for Graft-versus-Host Disease Prophylaxis in Patients with Acquired Aplastic Anemia Receiving Fludarabine-Based Conditioning.
Topics: Adolescent; Adult; Anemia, Aplastic; Child; Child, Preschool; Cyclosporine; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Male; Middle Aged; Retrospective Studies; Transplantation Conditioning; Vidarabine; Young Adult | 2020 |
Aplastic anemia in a patient with CVID due to NFKB1 haploinsufficiency.
Topics: Anemia, Aplastic; Benzoates; Bone Marrow; Common Variable Immunodeficiency; Cyclosporine; Exome Sequencing; Female; Genetic Predisposition to Disease; Haploinsufficiency; Humans; Hydrazines; Middle Aged; NF-kappa B; NF-kappa B p50 Subunit; Pyrazoles; Signal Transduction | 2020 |
Cyclosporine/methotrexate versus tacrolimus/methotrexate with or without anti-thymocyte globulin as GVHD prophylaxis in adult patients with aplastic anemia.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Cohort Studies; Cyclosporine; Drug Therapy, Combination; Female; Follow-Up Studies; Graft vs Host Disease; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Pre-Exposure Prophylaxis; Retrospective Studies; Survival Rate; Tacrolimus; Transplantation Conditioning; Young Adult | 2021 |
[Reference guide for the treatment of aplastic anemia].
Topics: Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Transplantation Conditioning | 2020 |
[Prediction and treatment prospect of immunosuppressive therapy in patients with severe aplastic anemia].
Topics: Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Humans; Immunosuppression Therapy; Immunosuppressive Agents | 2020 |
[Immunosupressive therapy of aplastic anemia patients: successes and failures (single center experiment 2007-2016)].
Topics: Adult; Anemia, Aplastic; Animals; Antilymphocyte Serum; Cyclosporine; Horses; Humans; Immunosuppressive Agents; Treatment Outcome | 2020 |
Effectiveness and safety of tacrolimus with or without eltrombopag, as a part of immunosuppressive treatment of aplastic anemia in adults: a retrospective case series.
Topics: Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Benzoates; Cyclosporine; Drug Eruptions; Female; Gingival Hypertrophy; Hirsutism; Humans; Hydrazines; Immunosuppressive Agents; Male; Middle Aged; Pyrazoles; Retrospective Studies; Tacrolimus | 2021 |
Effective treatment of aplastic anemia secondary to chemoradiotherapy using cyclosporine A.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Chemoradiotherapy; Cyclosporine; Humans; Immunosuppressive Agents; Treatment Outcome | 2021 |
Gum Hypertrophy from Cyclosporine.
Topics: Anemia, Aplastic; Child; Cyclosporine; Gingiva; Humans; Hypertrophy; Immunosuppressive Agents; Male | 2021 |
Efficacy and safety of eltrombopag in the first-line therapy of severe aplastic anemia in children.
Topics: Anemia, Aplastic; Animals; Antilymphocyte Serum; Benzoates; Child; Cyclosporine; Female; Humans; Hydrazines; Immunosuppressive Agents; Male; Pyrazoles; Rabbits; Retrospective Studies; Treatment Outcome | 2021 |
Hematopoietic stem progenitor cells lacking HLA differ from those lacking GPI-anchored proteins in the hierarchical stage and sensitivity to immune attack in patients with acquired aplastic anemia.
Topics: Adult; Aged; Aged, 80 and over; Anemia, Aplastic; Cyclosporine; Female; Follow-Up Studies; GPI-Linked Proteins; Granulocytes; Hematopoietic Stem Cells; HLA Antigens; Humans; Immunosuppressive Agents; Male; Middle Aged; Retrospective Studies; Young Adult | 2021 |
Eltrombopag in children with severe aplastic anemia.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Benzoates; Child; Cyclosporine; Humans; Hydrazines; Immunosuppressive Agents; Pyrazoles; Retrospective Studies; Treatment Outcome | 2021 |
Adult aplastic anemia in Thailand: incidence and treatment outcome from a prospective nationwide population-based study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Female; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Incidence; Male; Middle Aged; Prospective Studies; Thailand; Treatment Outcome; Young Adult | 2021 |
Ursodeoxycholic acid markedly promotes the absorption of microemulsion-formulated cyclosporine A: A case report.
Topics: Anemia, Aplastic; Cyclosporine; Emulsions; Humans; Immunosuppressive Agents; Liver Function Tests; Male; Ursodeoxycholic Acid; Young Adult | 2022 |
[Analysis of the Outcome and Prognostic Factors of Cyclosporine A in Children with Non-severe Aplastic Anemia].
Topics: Anemia, Aplastic; Child; Child, Preschool; Cyclosporine; Female; Humans; Immunosuppressive Agents; Male; Prognosis; Retrospective Studies; Treatment Outcome | 2021 |
The herbal decoction modified Danggui Buxue Tang attenuates immune-mediated bone marrow failure by regulating the differentiation of T lymphocytes in an immune-induced aplastic anemia mouse model.
Topics: Anemia, Aplastic; Angelica sinensis; Animals; Astragalus propinquus; Bone Marrow; Cell Differentiation; Cyclosporine; Disease Models, Animal; Drugs, Chinese Herbal; Female; GATA3 Transcription Factor; Humans; Immunosuppressive Agents; Medicine, Chinese Traditional; Mice; Mice, Inbred BALB C; Nuclear Receptor Subfamily 1, Group F, Member 3; Ranunculaceae; STAT3 Transcription Factor; T-Box Domain Proteins; Th1 Cells; Th17 Cells; Th2 Cells | 2017 |
Modified immunosuppressive therapy with porcine antilymphocyte globulin plus delayed cyclosporine A in children with severe aplastic anemia.
Topics: Adolescent; Anemia, Aplastic; Animals; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Male; Retrospective Studies; Severity of Illness Index; Survival Rate; Swine; Treatment Outcome | 2018 |
Comparative study of porcine anti-human lymphocyte immunoglobulin and rabbit anti-human thymocyte immunoglobulin as a first-line treatment of acquired severe aplastic anemia.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Animals; Antilymphocyte Serum; Child; Cyclosporine; Female; Humans; Immunologic Factors; Immunosuppressive Agents; Kaplan-Meier Estimate; Male; Middle Aged; Progression-Free Survival; Rabbits; Recurrence; Retrospective Studies; Severity of Illness Index; Swine; Young Adult | 2018 |
Nationwide survey on the use of horse antithymocyte globulins (ATGAM) in patients with acquired aplastic anemia: A report on behalf of the French Reference Center for Aplastic Anemia.
Topics: Adolescent; Adult; Anemia, Aplastic; Animals; Antilymphocyte Serum; Child; Cyclosporine; Drug Therapy, Combination; Female; France; Hemorrhage; Horses; Humans; Infections; Male; Middle Aged; Surveys and Questionnaires; Treatment Outcome; Young Adult | 2018 |
Acquired amegakaryocytic thrombocytopenia and red cell aplasia in a patient with thymoma progressing to aplastic anemia successfully treated with allogenic stem cell transplantation.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Diseases; Cyclosporine; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppression Therapy; Middle Aged; Prednisolone; Purpura, Thrombocytopenic; Red-Cell Aplasia, Pure; Thymoma; Thymus Neoplasms | 2019 |
Danazol increases T regulatory cells in patients with aplastic anemia.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Danazol; Female; Humans; Male; Middle Aged; Prospective Studies; T-Lymphocytes, Regulatory | 2018 |
First line treatment of aplastic anemia with thymoglobuline in Europe and Asia: Outcome of 955 patients treated 2001-2012.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia, Aplastic; Antilymphocyte Serum; Asia; Child; Child, Preschool; Cyclosporine; Drug Therapy, Combination; Europe; Humans; Infant; Middle Aged; Prognosis; Risk Factors; Survival Analysis; Treatment Outcome; Young Adult | 2018 |
Cyclosporin A inhibits adipogenic differentiation and regulates immunomodulatory functions of murine mesenchymal stem cells.
Topics: Adipogenesis; Anemia, Aplastic; Animals; Apoptosis; Bone Marrow; Cell Proliferation; Cells, Cultured; Cyclosporine; Immunosuppressive Agents; Interleukin-6; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL | 2018 |
Aplastic Anemia as an Immune-mediated Complication of Thymoma: A Case Report.
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Humans; Immunosuppressive Agents; Male; Thymoma; Treatment Outcome | 2018 |
Cyclosporine-Olanzapine Drug-Drug Interaction.
Topics: Adult; Anemia, Aplastic; Antipsychotic Agents; Cyclosporine; Drug Interactions; Humans; Immunosuppressive Agents; Male; Myelodysplastic Syndromes; Olanzapine; Schizophrenia, Paranoid; Young Adult | 2018 |
Comparison of two dosages of rabbit antithymocyte globulin (r-ATG) in treating children with severe aplastic anemia.
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Child; Cyclosporine; Dose-Response Relationship, Drug; Female; Humans; Male; Recurrence; Retrospective Studies; Treatment Outcome | 2018 |
Effects and Predictive Factors of Immunosuppressive Therapy Combined with Umbilical Cord Blood Infusion in Patients with Severe Aplastic Anemia.
Topics: Adolescent; Adult; Anemia, Aplastic; Animals; Antilymphocyte Serum; Blood Platelets; Child; Cohort Studies; Cyclosporine; Female; Fetal Blood; Humans; Immunosuppressive Agents; Leukocyte Count; Male; Middle Aged; Neutrophils; Rabbits; Severity of Illness Index; Survival Rate; Treatment Outcome; Young Adult | 2018 |
Rabbit antithymocyte globulin dose does not affect response or survival as first-line therapy for acquired aplastic anemia: a multicenter retrospective study.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Disease-Free Survival; Female; Humans; Infant; Male; Middle Aged; Retrospective Studies; Survival Rate | 2018 |
A case of reversible cerebral vasoconstriction syndrome developing during treatment of adult aplastic anemia.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Female; Humans; Magnetic Resonance Angiography; Middle Aged; Syndrome; Vasospasm, Intracranial | 2019 |
[Acquired aplastic anemia. Experience in a public hospital].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia, Aplastic; Antilymphocyte Serum; Combined Modality Therapy; Cyclosporine; Hospitals, Public; Humans; Immunosuppressive Agents; Kaplan-Meier Estimate; Middle Aged; Severity of Illness Index; Stem Cell Transplantation; Time Factors; Young Adult | 2018 |
Cyclosporin A-related cerebral venous sinus thrombosis: A case report.
Topics: Adult; Anemia, Aplastic; Cyclosporine; Female; Humans; Immunosuppressive Agents; Sinus Thrombosis, Intracranial | 2018 |
Cyclosporine Therapy in Patients with Transfusion-independent Non-severe Aplastic Anemia: A Retrospective Analysis.
Topics: Adult; Aged; Aged, 80 and over; Anemia, Aplastic; Antilymphocyte Serum; Blood Transfusion; Cohort Studies; Cyclosporine; Female; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Male; Middle Aged; Platelet Transfusion; Renal Insufficiency; Retrospective Studies; Thrombocytopenia; Treatment Outcome; Young Adult | 2019 |
Immunosuppressive therapy for aplastic anemia: a single-center experience from western India.
Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Chemotherapy-Induced Febrile Neutropenia; Child; Cyclosporine; Disease-Free Survival; Female; Humans; Hypertension; Immunosuppression Therapy; India; Infections; Intracranial Hemorrhages; Male; Retrospective Studies; Survival Rate | 2019 |
Evaluating the Efficacy and Anti-infective Effect of High-dose Intravenous Immunoglobulin Adjuvant Therapy for Acquired Aplastic Anemia Children.
Topics: Anemia, Aplastic; Animals; Anti-Infective Agents; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Female; Humans; Immunoglobulins, Intravenous; Immunosuppression Therapy; Infection Control; Infections; Male; Rabbits; Retrospective Studies | 2019 |
Multidrug-resistant Aeromonas hydrophila causing fatal bilateral necrotizing fasciitis in an immunocompromised patient: a case report.
Topics: Adult; Aeromonas hydrophila; Anemia, Aplastic; Cyclosporine; Drug Resistance, Multiple, Bacterial; Fasciitis, Necrotizing; Fatal Outcome; Gram-Negative Bacterial Infections; Humans; Immunocompromised Host; Male; Sepsis; Soft Tissue Infections | 2018 |
Cyclosporine-Induced Gingival Hypertrophy.
Topics: Anemia, Aplastic; Child; Cyclosporine; Gingival Hypertrophy; Humans; Immunosuppressive Agents | 2019 |
Antithymocyte globulin and cyclosporin: standard of care also for older patients with aplastic anemia.
Topics: Aged; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Humans; Immunosuppressive Agents; Standard of Care; Surveys and Questionnaires | 2019 |
Eltrombopag combined with cyclosporine may have an effect on very severe aplastic anemia.
Topics: Anemia, Aplastic; Benzoates; Cyclosporine; Drug Therapy, Combination; Female; Hematopoiesis; Humans; Hydrazines; Immunosuppressive Agents; Middle Aged; Pyrazoles; Uterine Hemorrhage | 2019 |
Development of hemolytic paroxysmal nocturnal hemoglobinuria without graft loss following hematopoietic stem cell transplantation for acquired aplastic anemia.
Topics: Adolescent; Anemia, Aplastic; Bone Marrow Cells; Chimerism; Cyclosporine; Diabetes Mellitus, Type 1; Graft Survival; Hematopoietic Stem Cell Transplantation; Hemoglobinuria, Paroxysmal; Hemolysis; Humans; Immunosuppressive Agents; Male; Membrane Proteins; Mutation; Neutrophils; Recurrence; Thrombocytopenia; Thrombosis; Treatment Outcome | 2019 |
Reduced dose of post-transplantation cyclophosphamide compared to ATG for graft-versus-host disease prophylaxis in recipients of mismatched unrelated donor hematopoietic cell transplantation: a single-center study.
Topics: Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Diseases; Bone Marrow Failure Disorders; Cyclophosphamide; Cyclosporine; Drug Evaluation; Female; Graft Survival; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Hemoglobinuria, Paroxysmal; Histocompatibility; HLA Antigens; Humans; Immunosuppressive Agents; Incidence; Male; Middle Aged; Mycophenolic Acid; Neoplasms; Retrospective Studies; T-Lymphocytes; Tissue Donors | 2019 |
The oral microbiome of patients undergoing treatment for severe aplastic anemia: a pilot study.
Topics: Adult; Aged; Anemia, Aplastic; Anti-Bacterial Agents; Antilymphocyte Serum; Benzoates; Biodiversity; Cyclosporine; Dental Health Surveys; DNA, Bacterial; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Hydrazines; Immunocompromised Host; Immunosuppressive Agents; Male; Microbiota; Middle Aged; Mouth; Pilot Projects; Pyrazoles; Ribotyping; Sequence Analysis, DNA; Smoking; T-Lymphocytes; Tongue; Young Adult | 2019 |
Immunosuppressive therapy (IST) in adult patients with acquired aplastic anemia (AA): A single-center experience over the past 15 years.
Topics: Adult; Aged; Aged, 80 and over; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Drug Therapy, Combination; Erythrocyte Indices; Female; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Male; Middle Aged; Recurrence; Retrospective Studies; Severity of Illness Index; Survival Analysis; Treatment Outcome; Young Adult | 2019 |
Successful treatment of aplastic anaemia with cyclosporine during pregnancy.
Topics: Adult; Anemia, Aplastic; Blood Transfusion; Combined Modality Therapy; Cyclosporine; Female; Humans; Live Birth; Pregnancy; Pregnancy Complications, Hematologic; Treatment Outcome | 2019 |
Current Treatment Patterns of Aplastic Anemia in China: A Prospective Cohort Registry Study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allografts; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; China; Cyclosporine; Disease-Free Survival; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppression Therapy; Infant; Infant, Newborn; Male; Medicine, Chinese Traditional; Middle Aged; Prospective Studies; Registries; Survival Rate | 2019 |
A rare side effect: eltrombopag associated hyperpigmentation.
Topics: Aged; Anemia, Aplastic; Benzoates; Cyclosporine; Drug Therapy, Combination; Female; Humans; Hydrazines; Melanosis; Pyrazoles | 2020 |
Atypical Chronic Myeloid Leukemia in a Patient with Aplastic Anemia.
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocols; Cyclosporine; Cytarabine; Etoposide; Fatal Outcome; Granulocyte Colony-Stimulating Factor; Humans; Imidazoles; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Methylprednisolone; Prednisolone; Pyridazines | 2019 |
Predicting response to porcine antilymphocyte globulin plus cyclosporine A in children with acquired severe aplastic anemia.
Topics: Adolescent; Anemia, Aplastic; Animals; Antilymphocyte Serum; Cell Count; Child; Child, Preschool; Cyclosporine; Disease-Free Survival; Female; Humans; Immunosuppressive Agents; Infant; Male; Predictive Value of Tests; Prognosis; Reticulocytes; Swine; Treatment Outcome | 2019 |
Clinical outcomes of immunosuppressive therapy for severe aplastic anemia patients with absolute neutrophil count of zero.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Female; Humans; Immunosuppressive Agents; Infections; Kaplan-Meier Estimate; Leukocyte Count; Male; Middle Aged; Neutrophils; Prognosis; Retrospective Studies; Treatment Outcome; Young Adult | 2019 |
Aplastic anemia in children: How good is immunosuppressive therapy?
Topics: Anemia, Aplastic; Antilymphocyte Serum; Child; Cyclosporine; Disease-Free Survival; Female; Follow-Up Studies; Humans; Immunosuppression Therapy; Male; Survival Rate | 2019 |
Reactivation and dynamics of cytomegalovirus and Epstein-Barr virus after rabbit antithymocyte globulin and cyclosporine for aplastic anemia.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Cytomegalovirus; Cytomegalovirus Infections; Epstein-Barr Virus Infections; Female; Herpesvirus 4, Human; Humans; Immunosuppressive Agents; Male; Middle Aged; Treatment Outcome; Viral Load; Virus Activation; Young Adult | 2019 |
Population pharmacokinetics of ciclosporin in Chinese children with aplastic anemia: effects of weight, renal function and stanozolol administration.
Topics: Adolescent; Anemia, Aplastic; Asian People; Body Weight; Child; Child, Preschool; Cyclosporine; Female; Humans; Immunosuppressive Agents; Infant; Kidney Function Tests; Male; Metabolic Clearance Rate; Prospective Studies; Stanozolol | 2013 |
Rabbit antithymocyte globulin treatment in childhood acquired severe aplastic anemia.
Topics: Adolescent; Anemia, Aplastic; Animals; Antilymphocyte Serum; Blood Transfusion; Child; Child, Preschool; Combined Modality Therapy; Cyclosporine; Female; Granulocyte Colony-Stimulating Factor; Horses; Humans; Immunosuppressive Agents; Infant; Male; Mycoses; Rabbits; Retrospective Studies; Species Specificity; T-Lymphocytes; Treatment Outcome; Turkey | 2014 |
[Therapeutic efficacy evaluation of rabbit anti-thymocyte globulin combined with cyclosporine A in children with aplastic anemia].
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Drug Therapy, Combination; Female; Humans; Lymphocyte Count; Lymphocyte Subsets; Male; Retrospective Studies; Treatment Outcome | 2013 |
Immunosuppressive therapy in adults with aplastic anaemia: single-institution experience from India.
Topics: Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Febrile Neutropenia; Female; Granulocyte Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Immunotherapy; India; Male; Middle Aged; Recurrence; Retrospective Studies; Survival Rate; Tertiary Care Centers; Treatment Outcome; Young Adult | 2013 |
[Clinical features of cytopenia with bone marrow hypoplasia in children: an analysis of 100 cases].
Topics: Adolescent; Anemia, Aplastic; Bone Marrow; Child; Child, Preschool; Cyclosporine; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Infant; Male; Myelodysplastic Syndromes; Pancytopenia | 2013 |
Respiratory and systemic infections in children with severe aplastic anemia on immunosuppressive therapy.
Topics: Adolescent; Adrenal Cortex Hormones; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Female; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Infant; Male; Pneumonia; Respiratory Tract Infections; Risk Factors; Sepsis; Treatment Outcome | 2013 |
Effectiveness and safety of rabbit anti-thymocyte globulin in Japanese patients with aplastic anemia.
Topics: Adult; Anemia, Aplastic; Antilymphocyte Serum; Asian People; Cyclosporine; Drug Therapy, Combination; Female; Humans; Immunoglobulins; Immunosuppressive Agents; Male; Middle Aged; Survival Rate; Time Factors; Treatment Outcome; Young Adult | 2013 |
[Predicting early response to immunosuppressive therapy in severe aplastic anemia by soluble transferrin receptor assay].
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Female; Humans; Immunosuppression Therapy; Male; Middle Aged; Receptors, Transferrin; Retrospective Studies; Sensitivity and Specificity; Treatment Outcome; Young Adult | 2013 |
[Inhibitory effects of tacrolimus on effector T cells from patients with severe aplastic anemia].
Topics: Adult; Aged; Anemia, Aplastic; CD4-CD8 Ratio; CD8-Positive T-Lymphocytes; Cell Proliferation; Cells, Cultured; Cyclosporine; Female; HLA-DR Antigens; Humans; Interleukin-2; Lymphotoxin-alpha; Male; Middle Aged; Tacrolimus; Young Adult | 2013 |
Salvage therapy of refractory severe aplastic anemia by decreasing cyclosporine dose regimen.
Topics: Anemia, Aplastic; Child; Cyclosporine; Female; Humans; Immunosuppressive Agents; Infant; Male; Salvage Therapy; Severity of Illness Index; Treatment Outcome | 2014 |
Two cases of concomitant acquired aplastic anemia and systemic mastocytosis.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Cells; Bone Marrow Examination; Cyclosporine; Humans; Male; Mast Cells; Mastocytosis, Systemic; Middle Aged; Prednisone | 2014 |
Long-term outcome after immunosuppressive therapy with horse or rabbit antithymocyte globulin and cyclosporine for severe aplastic anemia in children.
Topics: Adolescent; Anemia, Aplastic; Animals; Antilymphocyte Serum; Cell Transformation, Neoplastic; Child; Child, Preschool; Cyclosporine; Disease Progression; Female; Follow-Up Studies; Horses; Humans; Immunosuppressive Agents; Infant; Infant, Newborn; Male; Prognosis; Rabbits; Recurrence; Retrospective Studies; Risk Factors; Severity of Illness Index; Treatment Outcome | 2014 |
Prognostic value of paroxysmal nocturnal haemoglobinuria clone presence in aplastic anaemia patients treated with combined immunosuppression: results of two-centre prospective study.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Female; Flow Cytometry; Hemoglobinuria, Paroxysmal; Humans; Immunosuppressive Agents; Infant; Male; Middle Aged; Prognosis; Prospective Studies; Survival Analysis; Young Adult | 2014 |
Diagnosis and treatment of pediatric acquired aplastic anemia (AAA): an initial survey of the North American Pediatric Aplastic Anemia Consortium (NAPAAC).
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Female; Follow-Up Studies; Health Care Surveys; Humans; Immunosuppressive Agents; Infant; Male; North America; Practice Patterns, Physicians'; Prognosis; Siblings | 2014 |
[Hematologic improvement with deferasirox following tandem antithymocyte globulin treatment in a transfusion-dependent patient with severe aplastic anemia].
Topics: Anemia, Aplastic; Antilymphocyte Serum; Benzoates; Blood Transfusion; Cyclosporine; Deferasirox; Humans; Iron Chelating Agents; Male; Middle Aged; Transfusion Reaction; Treatment Outcome; Triazoles | 2013 |
Immunosuppressive therapy with horse anti-thymocyte globulin and cyclosporine as treatment for fulminant aplastic anemia in children.
Topics: Acute Disease; Adolescent; Anemia, Aplastic; Animals; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Female; Hematopoietic Stem Cell Transplantation; Histocompatibility Testing; Horses; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Male; Neutrophils; Prospective Studies; Severity of Illness Index; Survival Analysis; Treatment Outcome | 2014 |
Effects of immunosuppressive therapy in a patient with aplastic anemia-paroxysmal nocturnal hemoglobinuria (AA-PNH) syndrome during ongoing eculizumab treatment.
Topics: Aged; Anemia, Aplastic; Anti-Bacterial Agents; Antibodies, Monoclonal, Humanized; Antilymphocyte Serum; Bacteremia; Blood Transfusion; Combined Modality Therapy; Complement Inactivating Agents; Cyclosporine; Escherichia coli Infections; Female; Granulocyte Colony-Stimulating Factor; Hemoglobinuria, Paroxysmal; Hemolysis; Humans; Immunosuppressive Agents; Lenograstim; Recombinant Proteins; Shock, Septic; T-Lymphocytes; Urinary Tract Infections | 2014 |
Successful outcome of allogeneic stem cell transplantation in Seckel syndrome.
Topics: Alleles; Anemia, Aplastic; Bone Marrow Transplantation; Child; Cyclosporine; Dwarfism; Facies; Female; HLA Antigens; Humans; Living Donors; Male; Microcephaly; Middle Aged; Stem Cell Transplantation; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome | 2014 |
Granulocyte transfusion combined with granulocyte colony stimulating factor in severe infection patients with severe aplastic anemia: a single center experience from China.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Bacterial Infections; Child; Cyclosporine; Female; Granulocyte Colony-Stimulating Factor; Granulocytes; Humans; Immunosuppressive Agents; Leukocyte Transfusion; Male; Middle Aged; Mycoses; Retrospective Studies; Survival Rate; Young Adult | 2014 |
Elevated expression of CX3C chemokine receptor 1 mediates recruitment of T cells into bone marrow of patients with acquired aplastic anaemia.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Adhesion; Chemotaxis, Leukocyte; CX3C Chemokine Receptor 1; Cyclosporine; Humans; Immunosuppressive Agents; Integrin alpha4beta1; Prospective Studies; Receptors, Chemokine; Vascular Cell Adhesion Molecule-1 | 2014 |
On a class of optimal covariate-adjusted response adaptive designs for survival outcomes.
Topics: Adolescent; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Child; Child, Preschool; Clinical Trials, Phase III as Topic; Cyclosporine; Female; Graft vs Host Disease; Humans; Infant; Male; Methotrexate; Research Design; Survival Analysis; Treatment Outcome; Young Adult | 2016 |
Immune suppression for childhood acquired aplastic anemia and myelodysplastic syndrome: where next?
Topics: Anemia, Aplastic; Animals; Antilymphocyte Serum; Cyclosporine; Female; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Male; Pancytopenia | 2014 |
[Immunosuppressive therapy using antithymocyte globulin and cyclosporin A with or without human granulocyte colony-stimulating factor in children with acquired severe aplastic anemia].
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Drug Therapy, Combination; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Infant; Male; Retrospective Studies; Risk Factors; Severity of Illness Index; Survival Rate; Treatment Outcome | 2014 |
ATG-Fresenius S combined with cyclosporine a: an effective immunosuppressive therapy for children with aplastic anemia.
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Infant; Male; Prognosis; Retrospective Studies; Secondary Prevention; Survival Rate | 2014 |
[Salvage therapy for severe aplastic anemia after allogenenic hematopoietic cell transplant].
Topics: Anemia, Aplastic; Cyclosporine; Hematopoietic Stem Cell Transplantation; Humans; Recurrence; Salvage Therapy | 2014 |
Pilot study using tacrolimus rather than cyclosporine plus antithymocyte globulin as an immunosuppressive therapy regimen option for severe aplastic anemia in adults.
Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Blood Component Transfusion; Cyclosporine; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Male; Middle Aged; Severity of Illness Index; Tacrolimus; Treatment Outcome; Young Adult | 2014 |
Massive hyper-reactive hematopoietic nests in bilateral iliac bones in a patient with mild aplastic anemia.
Topics: Adolescent; Anemia, Aplastic; Bone Marrow; Cyclosporine; Humans; Immunosuppressive Agents; Male | 2014 |
Paroxysmal nocturnal hemoglobinuria clones in children with acquired aplastic anemia: a multicentre study.
Topics: Adolescent; Anemia, Aplastic; Child; Child, Preschool; Cyclosporine; Glycosylphosphatidylinositols; Hemoglobinuria, Paroxysmal; Humans; Immunosuppressive Agents; Infant; Infant, Newborn; Longitudinal Studies; Treatment Outcome | 2014 |
Good outcome of haploidentical hematopoietic SCT as a salvage therapy in children and adolescents with acquired severe aplastic anemia.
Topics: Adolescent; Anemia, Aplastic; Busulfan; Child; Child, Preschool; Cohort Studies; Cord Blood Stem Cell Transplantation; Cyclosporine; Female; Graft Survival; Graft vs Host Disease; Hematopoiesis; Hematopoietic Stem Cell Transplantation; Humans; Male; Neutrophils; Salvage Therapy; Transplantation Conditioning; Treatment Outcome; Young Adult | 2014 |
Outcomes of immunosuppressant therapy with lower dose of antithymocyte globulin and cyclosporine in aplastic anemia.
Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Child; Cyclosporine; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Immunotherapy; India; Male; Middle Aged; Retrospective Studies; Survival Analysis; Treatment Outcome; Young Adult | 2015 |
First-line treatment for severe aplastic anemia in children: bone marrow transplantation from a matched family donor versus immunosuppressive therapy.
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cyclosporine; Family; Female; Follow-Up Studies; Graft Rejection; Graft vs Host Disease; Histocompatibility; HLA Antigens; Humans; Immunosuppressive Agents; Infant; Infant, Newborn; Male; Neoplasm Staging; Prognosis; Prospective Studies; Retrospective Studies; Severity of Illness Index; Survival Rate; Tissue Donors; Transplantation Conditioning; Transplantation, Homologous | 2014 |
Induction of short-term remission with single agent eltrombopag in refractory nucleophosmin-1-mutated acute myeloid leukemia.
Topics: Anemia, Aplastic; Animals; Antilymphocyte Serum; Cyclosporine; Female; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Male; Pancytopenia | 2014 |
Efficacy and safety of immunosuppressive therapy in the treatment of seronegative hepatitis associated aplastic anemia.
Topics: Adolescent; Adult; Anemia, Aplastic; Antiviral Agents; Child; Cyclosporine; Dose-Response Relationship, Drug; Female; Hepatitis B; Hepatitis B virus; Humans; Immunoglobulins; Immunosuppressive Agents; Male; Microbial Sensitivity Tests; Middle Aged; Young Adult | 2014 |
Population pharmacokinetics and individualized dosage prediction of cyclosporine in allogeneic hematopoietic stem cell transplant patients.
Topics: Adult; Anemia, Aplastic; ATP Binding Cassette Transporter, Subfamily B; Cohort Studies; Cyclosporine; Cytochrome P-450 CYP3A; Female; Graft Rejection; Hematologic Diseases; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Models, Biological; Myelodysplastic Syndromes; Polymorphism, Genetic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Transplantation, Homologous | 2014 |
Polymorphisms in TNF and IFNG are associated with clinical characteristics of aplastic anemia in Argentinean population.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Argentina; Child; Child, Preschool; Cyclosporine; Dinucleotide Repeats; Drug Therapy, Combination; Female; Gene Frequency; Genotype; Humans; Immunosuppressive Agents; Interferon-gamma; Male; Middle Aged; Polymorphism, Single Nucleotide; Retrospective Studies; Treatment Outcome; Tumor Necrosis Factor-alpha; Young Adult | 2015 |
Diagnostic and management dilemma of a pancreas-kidney transplant recipient with aplastic anaemia.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Diabetes Mellitus, Type 1; Female; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Transplantation; Middle Aged; Mycophenolic Acid; Pancreas Transplantation; Prednisolone; Tacrolimus | 2014 |
Haploidentical hematopoietic SCT for acquired severe aplastic anemia using post-transplant high-dose CY.
Topics: Allografts; Anemia, Aplastic; Child; Cyclosporine; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents | 2015 |
[Therapeutic efficacy of second allo-HSCT for aplastic anemia after failure of first allo-HSCT].
Topics: Allografts; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Disease-Free Survival; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Methotrexate; Mycophenolic Acid; Retrospective Studies | 2014 |
[Retrospective analysis of therapeutic efficacy of haploidentical allogeneic hematopoietic stem cell transplantation for severe aplastic anemia].
Topics: Adolescent; Allografts; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Graft vs Host Disease; Haploidy; Hematopoietic Stem Cell Transplantation; Humans; Retrospective Studies; Siblings; Survival Rate; Tissue Donors; Transplantation Conditioning; Vidarabine | 2014 |
[Comparison between two different dose of r-ATG combined with CsA for treating children with severe aplastic anemia].
Topics: Anemia, Aplastic; Animals; Antilymphocyte Serum; Child; Cyclosporine; Drug Combinations; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Leukemia, Monocytic, Acute; Male; Rabbits; Retrospective Studies; Survival Rate; Treatment Outcome | 2014 |
[Residual hematopoiesis is an important prognostic factor of immunosuppressive therapy in severe aplastic anemia].
Topics: Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow; Cyclosporine; Hematopoiesis; Humans; Immunosuppressive Agents; Leukocyte Count; Prognosis; Retrospective Studies; ROC Curve | 2014 |
Early intensified intravenous cyclosporine therapy predicts favorable response to immunosuppressive therapy with rabbit antithymocyte globulin in patients with severe aplastic anemia.
Topics: Administration, Oral; Adult; Aged; Anemia, Aplastic; Animals; Antilymphocyte Serum; Cyclosporine; Drug Combinations; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Injections, Intravenous; Male; Middle Aged; Prognosis; Rabbits; Recurrence; Survival Rate; Young Adult | 2015 |
[Efficacies of hematopoietic stem cell transplantation for severe aplastic anemia: a report of 43 patients].
Topics: Adolescent; Adult; Anemia, Aplastic; Child; Cyclophosphamide; Cyclosporine; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Male; Methotrexate; Middle Aged; Mycophenolic Acid; Siblings; Transplantation Conditioning; Vidarabine; Young Adult | 2014 |
Porcine antilymphocyte globulin (p-ALG) plus cyclosporine A (CsA) treatment in acquired severe aplastic anemia: a retrospective multicenter analysis.
Topics: Adolescent; Adult; Anemia, Aplastic; Animals; Antilymphocyte Serum; Cyclosporine; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Retrospective Studies; Severity of Illness Index; Survival Rate; Swine; Treatment Outcome; Young Adult | 2015 |
The combined use of cytokine-induced killer cells and cyclosporine a for the treatment of aplastic anemia in a mouse model.
Topics: Adoptive Transfer; Anemia, Aplastic; Animals; Bone Marrow; Cyclosporine; Cytokine-Induced Killer Cells; Cytokines; Disease Models, Animal; Erythrocyte Indices; Immunophenotyping; Immunosuppressive Agents; Leukocytes, Mononuclear; Male; Mice; Phenotype; Treatment Outcome | 2015 |
[Short and long term efficacy of immunosuppressive therapy and survival in adult severe aplastic anemia].
Topics: Adult; Anemia, Aplastic; Blood Transfusion; Cyclosporine; Humans; Immunosuppressive Agents; Leukocyte Count; Logistic Models; Neutrophils; Reticulocytes; Survival Rate | 2015 |
Immunosuppressive therapy in patients with aplastic anemia: a single-center retrospective study.
Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Danazol; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Kaplan-Meier Estimate; Male; Middle Aged; Proportional Hazards Models; Retrospective Studies; Treatment Outcome; Young Adult | 2015 |
Model-Based Determination of Effective Blood Concentrations of Cyclosporine for Neutrophil Response in the Treatment of Severe Aplastic Anemia in Children.
Topics: Adolescent; Anemia, Aplastic; Child; Child, Preschool; Cyclosporine; Female; Humans; Immunosuppressive Agents; Infant; Male; Models, Biological; Neutrophils; Nonlinear Dynamics; Retrospective Studies; Severity of Illness Index; Time Factors | 2015 |
Diagnosis and management of acquired aplastic anemia in childhood. Guidelines from the Marrow Failure Study Group of the Pediatric Haemato-Oncology Italian Association (AIEOP).
Topics: Anemia, Aplastic; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antilymphocyte Serum; Antirheumatic Agents; Bone Marrow; Child; Cyclosporine; Disease Management; Hematopoietic Stem Cell Transplantation; Histocompatibility Testing; Humans; Immunosuppressive Agents; Organophosphates; Pancytopenia; Siblings; Unrelated Donors | 2015 |
Cyclosporine-related brainstem atypical posterior reversible leukoencephalopathy syndrome following hematopoietic stem cell transplant.
Topics: Adult; Anemia, Aplastic; Brain Stem; Cyclosporine; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Male; Posterior Leukoencephalopathy Syndrome; Young Adult | 2016 |
Long-term follow-up study of porcine anti-human thymocyte immunoglobulin therapy combined with cyclosporine for severe aplastic anemia.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Animals; Antilymphocyte Serum; Child; Clonal Evolution; Cyclosporine; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Kaplan-Meier Estimate; Male; Middle Aged; Odds Ratio; Recurrence; Severity of Illness Index; Swine; Time Factors; Treatment Outcome; Young Adult | 2016 |
Tacrolimus versus Cyclosporine after Hematopoietic Cell Transplantation for Acquired Aplastic Anemia.
Topics: Age Factors; Anemia, Aplastic; Cyclosporine; Drug Therapy, Combination; Female; Graft Survival; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Living Donors; Male; Methotrexate; Proportional Hazards Models; Retrospective Studies; Tacrolimus; Transplantation Conditioning; Treatment Outcome | 2015 |
Antithymocyte globulin combined with cyclosporine A down-regulates T helper 1 cells by modulating T cell immune response cDNA 7 in aplastic anemia.
Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Down-Regulation; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Male; Middle Aged; T-Lymphocytes; Vacuolar Proton-Translocating ATPases; Young Adult | 2015 |
Outcome of a novel immunosuppressive strategy of cyclosporine, levamisole and danazol for severe aplastic anemia.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Child; Child, Preschool; Clonal Evolution; Cyclosporine; Danazol; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Kaplan-Meier Estimate; Levamisole; Male; Middle Aged; Prognosis; Recurrence; Retrospective Studies; Severity of Illness Index; Treatment Outcome; Young Adult | 2015 |
Allogeneic hematopoietic stem cell transplantation in children with aplastic anemia.
Topics: Adolescent; Anemia, Aplastic; Animals; Antilymphocyte Serum; Bone Marrow Transplantation; Child; Child, Preschool; China; Cyclosporine; Female; Graft vs Host Disease; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; HLA Antigens; Humans; Male; Rabbits; Transplantation, Homologous | 2015 |
Similar outcome of upfront-unrelated and matched sibling stem cell transplantation in idiopathic paediatric aplastic anaemia. A study on behalf of the UK Paediatric BMT Working Party, Paediatric Diseases Working Party and Severe Aplastic Anaemia Working P
Topics: Adenoviridae Infections; Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Blood Transfusion; Bone Marrow Transplantation; Case-Control Studies; Child; Child, Preschool; Cyclosporine; Disease-Free Survival; Female; Follow-Up Studies; Graft vs Host Disease; Herpesviridae Infections; Histocompatibility; Humans; Immunosuppressive Agents; Infant; Kaplan-Meier Estimate; Length of Stay; Living Donors; Male; Peripheral Blood Stem Cell Transplantation; Postoperative Complications; Primary Graft Dysfunction; Quality of Life; Retrospective Studies; Siblings; Survival Rate; T-Lymphocytes; Treatment Outcome; Virus Activation; Young Adult | 2015 |
[Efficacy of Nonmyeloablative Allogeneic Hematopoietic Stem Cells for 14 Case of Severe Acquired Aplastic Anemia].
Topics: Allografts; Anemia, Aplastic; Antilymphocyte Serum; Cyclophosphamide; Cyclosporine; Disease-Free Survival; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Mycophenolic Acid; Neutrophils; Siblings; Tissue Donors; Transplantation Conditioning; Vidarabine | 2015 |
Comparison of immune manifestations between refractory cytopenia of childhood and aplastic anemia in children: A single-center retrospective study.
Topics: Adolescent; Agammaglobulinemia; Anemia, Aplastic; Antilymphocyte Serum; Autoantibodies; Autoimmune Diseases; Bone Marrow; Child; Child, Preschool; Comorbidity; Complement C3; Complement C4; Cyclosporine; Female; Gene Rearrangement, delta-Chain T-Cell Antigen Receptor; Humans; Hypergammaglobulinemia; Immunoglobulins; Immunosuppressive Agents; Incidence; Infant; Lymphocyte Count; Lymphocyte Subsets; Male; Myelodysplastic Syndromes; Retrospective Studies; Time Factors | 2015 |
Immunosuppressive Therapy for Aplastic Anaemia.
Topics: Adult; Anemia, Aplastic; Antilymphocyte Serum; Child; Cyclosporine; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Opportunistic Infections; Outcome Assessment, Health Care; Patient Selection; Recurrence; Remission Induction | 2015 |
Markedly High Plasma Thrombopoietin (TPO) Level is a Predictor of Poor Response to Immunosuppressive Therapy in Children With Acquired Severe Aplastic Anemia.
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Biomarkers; Child; Child, Preschool; Cyclosporine; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunosuppressive Agents; Male; Proportional Hazards Models; Thrombopoietin; Treatment Outcome | 2016 |
[Outcomes of allogeneic hematopoietic stem cell transplantation for 18 patients with paroxysmal nocturnal haemoglobinuria].
Topics: Anemia, Aplastic; Antilymphocyte Serum; Busulfan; Cyclophosphamide; Cyclosporine; Disease-Free Survival; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Hemoglobinuria, Paroxysmal; Humans; Methotrexate; Mycophenolic Acid; Retrospective Studies; Siblings; Tacrolimus; Transplantation Conditioning; Treatment Outcome; Unrelated Donors; Vidarabine | 2015 |
Cyclosporine restores hematopoietic function by compensating for decreased Tregs in patients with pure red cell aplasia and acquired aplastic anemia.
Topics: Adult; Aged; Aged, 80 and over; Anemia, Aplastic; Antigens, Differentiation, T-Lymphocyte; Cyclosporine; Female; Flow Cytometry; Hematopoiesis; Humans; Immune Tolerance; Immunophenotyping; Immunosuppressive Agents; Interferon-gamma Release Tests; Lymphocyte Count; Male; Middle Aged; Red-Cell Aplasia, Pure; Remission Induction; Retrospective Studies; Substance-Related Disorders; T-Lymphocyte Subsets; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory | 2016 |
[Comparison of two types of antithymocyte globulin in the treatment of children with aplastic anemia].
Topics: Androgens; Anemia, Aplastic; Animals; Antilymphocyte Serum; Blood Component Transfusion; Child; Cyclosporine; Humans; Rabbits; Survival Rate; T-Lymphocytes; Treatment Outcome | 2016 |
[Outcomes of very severe aplastic anemia patients with different absolute neutrophil counts after frontline immnunosuppressive therapy].
Topics: Anemia, Aplastic; Animals; Antilymphocyte Serum; Cyclosporine; Disease-Free Survival; Humans; Immunosuppressive Agents; Leukocyte Count; Neutrophils; Rabbits; Retrospective Studies; Survival Rate; Treatment Outcome | 2016 |
Immunosuppressive therapy for patients with Down syndrome and idiopathic aplastic anemia.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Transplantation; Child; Cyclosporine; Down Syndrome; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Treatment Outcome | 2016 |
Clinical significance and origin of leukocytes that lack HLA-A allele expression in patients with acquired aplastic anemia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Anemia, Aplastic; Antilymphocyte Serum; Biomarkers; Cell Lineage; Child; Child, Preschool; Cyclosporine; DNA Copy Number Variations; Female; Flow Cytometry; Gene Expression; Gene Frequency; Genetic Association Studies; Genotype; HLA-A Antigens; Humans; Leukocytes; Male; Middle Aged; Phenotype; Polymorphism, Single Nucleotide; Prognosis; Severity of Illness Index; Treatment Outcome; Young Adult | 2016 |
Efficacy of combination therapy with anti-thymocyte globulin and cyclosporine A as a first-line treatment in adult patients with aplastic anemia: a comparison of rabbit and horse formulations.
Topics: Adult; Anemia, Aplastic; Animals; Antilymphocyte Serum; Cyclosporine; Drug Therapy, Combination; Horses; Humans; Immunoglobulins; Immunosuppressive Agents; Rabbits; Treatment Outcome | 2016 |
Treatment of aplastic anaemia with lower-dose anti-thymocyte globulin produces similar response rates and survival as per standard dose anti-thymocyte globulin schedules.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia, Aplastic; Antilymphocyte Serum; Australia; Cyclosporine; Databases, Factual; Dose-Response Relationship, Drug; Female; Humans; Immunosuppressive Agents; Kaplan-Meier Estimate; Male; Middle Aged; Retrospective Studies; Young Adult | 2016 |
Pediatric cardiorespiratory failure successfully managed with venoarterial-venous extracorporeal membrane oxygenation: a case report.
Topics: Anemia, Aplastic; Child; Cyclophosphamide; Cyclosporine; Echocardiography; Extracorporeal Membrane Oxygenation; Female; Femoral Artery; Heart Failure; Hematopoietic Stem Cell Transplantation; Hemodynamics; Humans; Immunosuppressive Agents; Jugular Veins; Myocarditis; Respiratory Insufficiency | 2016 |
[Antithymocyte/Antilymphocyte globulin plus cyclosporine A therapy for the treatment of older patients with severe aplastic anemia].
Topics: Aged; Anemia, Aplastic; Animals; Antilymphocyte Serum; Cyclosporine; Humans; Rabbits; Retrospective Studies; Swine; Treatment Outcome | 2016 |
[The clinical feature and outcomes of severe aplastic anemia patients suffered from bacteremia following antithymocyte globulin].
Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Bacteremia; Child; Child, Preschool; Cyclosporine; Female; Hospitals; Humans; Immunosuppressive Agents; Male; Middle Aged; Risk Factors; Treatment Outcome; Young Adult | 2016 |
Long-term outcomes of 95 children with moderate aplastic anemia treated with horse antithymocyte globulin and cyclosporine.
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Blood Transfusion; Child; Child, Preschool; Cyclosporine; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Male; Prospective Studies; Survival Rate; Treatment Outcome | 2017 |
[Clinical Efficacy of Haploidentical Allo-HSCT of Reduced Intensity Preconditioning Combined with Induced Immune Tolerance after Transplantation for Severe Aplastic Anemia].
Topics: Anemia, Aplastic; Busulfan; Cyclophosphamide; Cyclosporine; Disease-Free Survival; Fathers; Hematopoietic Stem Cell Transplantation; Hematopoietic System; Humans; Immune Tolerance; Male; Methotrexate; T-Lymphocyte Subsets; Tissue Donors; Transplantation Conditioning; Treatment Outcome; Vidarabine | 2016 |
[Effect of Rabbit Anti-human Thymocyte Immunoglobulin Combined with Cyclosporin A on Severe Aplastic Anemia].
Topics: Adolescent; Anemia, Aplastic; Animals; Antilymphocyte Serum; Cyclosporine; Hospitalization; Humans; Immunosuppressive Agents; Rabbits; Thymocytes; Treatment Outcome | 2016 |
Outcome of anti-thymocyte immunoglobulin plus cyclosporine A for severe aplastic anaemia with chronic hepatitis B virus infection.
Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Drug Therapy, Combination; Female; Follow-Up Studies; Hepatitis B, Chronic; Humans; Immunosuppressive Agents; Male; Middle Aged; Retrospective Studies; Severity of Illness Index; Treatment Outcome; Young Adult | 2017 |
Unexpected complication after varicella: aplastic anemia.
Topics: Anemia, Aplastic; Biopsy, Needle; Blood Cell Count; Bone Marrow; Chickenpox; Child; Cyclosporine; Diagnosis, Differential; Drug Therapy, Combination; Female; Flow Cytometry; Follow-Up Studies; Humans; Immunosuppressive Agents; Methotrexate; Stem Cell Transplantation | 2008 |
Long-term outcome of pediatric patients with severe aplastic anemia treated with antithymocyte globulin and cyclosporine.
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cohort Studies; Cyclosporine; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Incidence; Male; Recurrence; Retrospective Studies; Survival Analysis; Time Factors; Treatment Outcome | 2008 |
Aplastic anaemia in association with coeliac disease: a series of three cases.
Topics: Adult; Anemia, Aplastic; Bone Marrow Transplantation; Celiac Disease; Combined Modality Therapy; Cyclosporine; Fatigue; Female; Humans; Immunosuppressive Agents; Middle Aged; Young Adult | 2008 |
Sustained complete molecular remission after imatinib discontinuation due to severe aplastic anemia.
Topics: Aged; Analgesics, Non-Narcotic; Anemia, Aplastic; Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Benzamides; Cyclosporine; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Mycoses; Piperazines; Pyrimidines; Remission Induction; Respiratory Tract Infections | 2009 |
Recurrence of hepatitis-associated aplastic anemia after a 10-year interval.
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Hepatitis; Humans; Immunosuppressive Agents; Male; Methylprednisolone; Recurrence; Time Factors | 2008 |
A child with human parvovirus B19 infection induced aplastic anemia and acute hepatitis: effectiveness of immunosuppressive therapy.
Topics: Acute Disease; Anemia, Aplastic; Anti-Inflammatory Agents; Antilymphocyte Serum; Child; Cyclosporine; Female; Hepatitis, Viral, Human; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Methylprednisolone; Parvoviridae Infections; Parvovirus B19, Human | 2008 |
Predicting response to immunosuppressive therapy and survival in severe aplastic anaemia.
Topics: Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Female; Humans; Immunosuppressive Agents; Logistic Models; Lymphocyte Count; Male; Middle Aged; Probability; Prognosis; Reticulocyte Count; Retrospective Studies; Survival Rate; Treatment Outcome | 2009 |
Complete response to tacrolimus in a child with severe aplastic anemia resistant to cyclosporin A.
Topics: Anemia, Aplastic; Anemia, Refractory; Child; Cyclosporine; Gingival Hyperplasia; Humans; Immunosuppressive Agents; Male; Tacrolimus | 2009 |
Outcomes of older patients (> or = 60 years) with acquired aplastic anaemia treated with immunosuppressive therapy.
Topics: Aged; Anemia, Aplastic; Animals; Antilymphocyte Serum; Chi-Square Distribution; Cyclosporine; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Kaplan-Meier Estimate; Male; Middle Aged; Recurrence; Retrospective Studies; Risk; Treatment Outcome | 2008 |
Expansion of haematopoietic stem cells from normal donors and bone marrow failure patients by recombinant hoxb4.
Topics: Anemia, Aplastic; Animals; Antigens, CD34; Bone Marrow Cells; Cells, Cultured; Cyclosporine; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Hematopoietic Stem Cells; Homeodomain Proteins; Humans; Immunosuppressive Agents; Mice; Mice, SCID; Myelodysplastic Syndromes; Recombinant Proteins; Transcription Factors | 2009 |
[Therapeutic effects of a combination of high-dose immunoglobulin and cyclosporine A in children with aplastic anemia].
Topics: Adolescent; Anemia, Aplastic; CD4-CD8 Ratio; Child; Child, Preschool; Cyclosporine; Female; Humans; Immunoglobulins; Infant; Logistic Models; Male; Retrospective Studies | 2009 |
Serial chimerism analyses indicate that mixed haemopoietic chimerism influences the probability of graft rejection and disease recurrence following allogeneic stem cell transplantation (SCT) for severe aplastic anaemia (SAA): indication for routine assess
Topics: Adolescent; Adult; Anemia, Aplastic; Child; Child, Preschool; Chimerism; Cyclosporine; Fanconi Anemia; Female; Follow-Up Studies; Graft Rejection; Humans; Immunosuppressive Agents; Male; Middle Aged; Polymerase Chain Reaction; Prognosis; Proportional Hazards Models; Recurrence; Stem Cell Transplantation; Survival Rate; Tandem Repeat Sequences; Time Factors; Transplantation Conditioning; Transplantation, Homologous; Young Adult | 2009 |
Is the early cyclosporine A level predictive of the outcome of immunosuppressive therapy in severe aplastic anemia?
Topics: Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Disease-Free Survival; Female; Humans; Immunosuppressive Agents; Kaplan-Meier Estimate; Korea; Male; Middle Aged; Multivariate Analysis; Prognosis; Retrospective Studies; T-Lymphocytes; Time Factors; Treatment Outcome; Young Adult | 2009 |
Immunosuppressive treatment for aplastic anemia: are we hitting the ceiling?
Topics: Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Recurrence; Sirolimus; Treatment Outcome | 2009 |
Antithymocyte globulin and cyclosporin in children with acquired aplastic anemia.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Child; Cyclosporine; Humans; Immunosuppressive Agents; Platelet Transfusion; Recurrence | 2009 |
[Preliminary study on predictors for selection of immunosuppressive therapy or androgens in treating aplastic anemia patients].
Topics: Adult; Aged; Androgens; Anemia, Aplastic; Cyclosporine; Female; GATA3 Transcription Factor; Humans; Immunosuppressive Agents; Logistic Models; Male; Middle Aged; T-Box Domain Proteins; T-Lymphocyte Subsets; Young Adult | 2009 |
Association of human leukocyte antigen class II alleles with response to immunosuppressive therapy in Korean aplastic anemia patients.
Topics: Adolescent; Adult; Aged; Alleles; Anemia, Aplastic; Antilymphocyte Serum; Asian People; Child; Child, Preschool; Cyclosporine; Female; HLA-D Antigens; Humans; Immunosuppressive Agents; Male; Middle Aged; Young Adult | 2010 |
Hairy cell leukemia responsive to anti-thymocyte globulin used as immunosuppressive therapy for aplastic anemia.
Topics: Aged; Anemia, Aplastic; Anesthetics, Combined; Antilymphocyte Serum; Antineoplastic Agents; Asian People; Cladribine; Cyclosporine; Diagnosis, Differential; Female; Humans; Immunosuppressive Agents; Leukemia, Hairy Cell; Pancytopenia; Treatment Outcome | 2009 |
Tacrolimus/Methotrexate versus cyclosporine/methotrexate as graft-versus-host disease prophylaxis in patients with severe aplastic anemia who received bone marrow transplantation from unrelated donors: results of matched pair analysis.
Topics: Anemia, Aplastic; Bone Marrow Transplantation; Cyclosporine; Female; Graft vs Host Disease; Humans; Immunosuppressive Agents; Male; Matched-Pair Analysis; Methotrexate; Survival Rate; Tacrolimus; Tissue Donors | 2009 |
Predictors of response to immunosuppressive therapy with antithymocyte globulin and cyclosporine and prognostic factors for survival in patients with severe aplastic anemia.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Animals; Antilymphocyte Serum; Cyclosporine; Disease-Free Survival; Female; Horses; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Leukocyte Count; Male; Middle Aged; Neutrophils; Rabbits; Reticulocyte Count; Retrospective Studies; Survival Rate | 2010 |
[Prognostic factors of immunosuppressive therapy in children acquired aplastic anemia].
Topics: Adolescent; Anemia, Aplastic; Animals; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Female; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Infant; Male; Prognosis; Rabbits; Retrospective Studies; Treatment Outcome | 2009 |
[Combination of rabbit antithymocyte globulin plus cyclosporin A as first-line immunosuppressive therapy for the childhood with severe aplastic anemia.].
Topics: Anemia, Aplastic; Animals; Antilymphocyte Serum; Cyclosporine; Humans; Immunosuppressive Agents; Rabbits; Treatment Outcome | 2009 |
Immunosuppressive therapy of cyclosporin A for severe benzene-induced haematopoietic disorders and a 6-month follow-up.
Topics: Adolescent; Adult; Anemia, Aplastic; Benzene; Bone Marrow Diseases; Cyclosporine; Female; Follow-Up Studies; Hematologic Tests; Humans; Immunosuppressive Agents; Myelodysplastic Syndromes; Occupational Exposure; Testosterone; Young Adult | 2010 |
Clinical course of non-severe aplastic anemia in adults.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Androgens; Anemia, Aplastic; Cyclosporine; Female; Humans; Immunosuppressive Agents; Korea; Male; Middle Aged; Oxymetholone; Prognosis; Risk Factors; Survival Analysis; Young Adult | 2010 |
Paroxysmal nocturnal hemoglobinuria clones in severe aplastic anemia patients treated with horse anti-thymocyte globulin plus cyclosporine.
Topics: Adult; Anemia, Aplastic; Animals; Antilymphocyte Serum; Clone Cells; Cyclosporine; Drug Therapy, Combination; Female; Hemoglobinuria, Paroxysmal; Horses; Humans; Immunosuppressive Agents; Male; Middle Aged; Prognosis; Retrospective Studies; Young Adult | 2010 |
Transmission of familial Mediterranean fever mutation after bone marrow transplantation and successful treatment with anakinra.
Topics: Anemia, Aplastic; Anti-Bacterial Agents; Antilymphocyte Serum; Antirheumatic Agents; Bone Marrow Transplantation; Cyclosporine; Familial Mediterranean Fever; Graft vs Host Disease; Humans; Immunosuppressive Agents; Informed Consent; Interleukin 1 Receptor Antagonist Protein; Male; Mutation; Stroke Volume; Transplantation, Homologous; Treatment Outcome; Young Adult | 2010 |
Aplastic anemia following hepatitis associated with human herpesvirus 6.
Topics: Anemia, Aplastic; Anti-Inflammatory Agents; Antilymphocyte Serum; Biopsy; Child, Preschool; Cyclosporine; Diagnosis, Differential; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Hepatitis, Viral, Human; Herpesvirus 6, Human; Humans; Immunosuppressive Agents; Liver; Liver Function Tests; Male; Prednisolone; Reverse Transcriptase Polymerase Chain Reaction; Roseolovirus Infections | 2010 |
Immunosuppression or immunostimulation for aplastic anemia? A blast from the past.
Topics: Anemia, Aplastic; Animals; Antilymphocyte Serum; Autoimmunity; Cell Transplantation; Cyclosporine; Hematopoiesis; Humans; Immunization; Immunosuppression Therapy; Interleukin-2; Leukocytes, Mononuclear; Lymphocyte Activation; Mice; Phytohemagglutinins | 2010 |
Fludarabine-based conditioning chemotherapy for allogeneic hematopoietic stem cell transplantation in acquired severe aplastic anemia.
Topics: Adolescent; Adult; Anemia, Aplastic; Antineoplastic Agents; Blood Platelets; Cyclophosphamide; Cyclosporine; Disease-Free Survival; Female; Graft Rejection; Graft Survival; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Male; Methotrexate; Neutrophils; Transplantation Chimera; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Vidarabine; Young Adult | 2011 |
The use of anti-human T lymphocyte porcine immunoglobulin and cyclosporine a to treat patients with acquired severe aplastic anemia.
Topics: Aged; Anemia, Aplastic; Animals; Confidence Intervals; Cyclosporine; Female; Humans; Immunoglobulins; Male; Middle Aged; Regression Analysis; Swine; T-Lymphocytes | 2010 |
[Treatment outcomes of 125 children with aplastic anemia].
Topics: Anemia, Aplastic; Antilymphocyte Serum; Child; Cyclosporine; Humans; Immunosuppressive Agents; Treatment Outcome | 2010 |
[Impact of cyclosporine A on the expression of T-bet, GATA-3, relevant signal transduction molecules, cytokine and Th1/Th2 balance in patients with chronic aplastic anemia].
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Case-Control Studies; Cyclosporine; Female; GATA3 Transcription Factor; Humans; Interferon-gamma; Interleukin-12; Interleukin-4; Male; Middle Aged; Signal Transduction; STAT4 Transcription Factor; STAT6 Transcription Factor; T-Box Domain Proteins; Th1 Cells; Th2 Cells; Young Adult | 2010 |
Predicting response to immunosuppressive therapy in childhood aplastic anemia.
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Infant; Leukocyte Count; Male; Multicenter Studies as Topic; Multivariate Analysis; Predictive Value of Tests; Prognosis; Retrospective Studies; Time Factors; Treatment Outcome | 2011 |
[Serial FDG-PET evaluation of a patchy pattern of hematopoiesis at diagnosis in aplastic anemia].
Topics: Anemia, Aplastic; Autoantibodies; Cyclosporine; Fluorodeoxyglucose F18; Hematopoiesis; Humans; Immunosuppressive Agents; Male; Middle Aged; Positron-Emission Tomography; Radiopharmaceuticals | 2011 |
Aplastic anemia successfully treated with rituximab: the possible role of aplastic anemia-associated autoantibodies as a marker for response.
Topics: Anemia, Aplastic; Antibodies, Antinuclear; Antibodies, Monoclonal, Murine-Derived; Antilymphocyte Serum; Autoantibodies; Biomarkers; Bone Marrow; Carbon-Carbon Double Bond Isomerases; Cyclosporine; Dodecenoyl-CoA Isomerase; Humans; Infant; Male; Microfilament Proteins; Remission Induction; Rituximab; T-Lymphocytes | 2011 |
Relapse of aplastic anemia in children after immunosuppressive therapy: a report from the Japan Childhood Aplastic Anemia Study Group.
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Incidence; Infant; Infant, Newborn; Japan; Male; Prospective Studies; Recurrence; Risk Factors | 2011 |
[Combination of rabbit antithymocyte globulin and cyclosporine A as first-line therapy for adult severe aplastic anemia].
Topics: Adolescent; Adult; Anemia, Aplastic; Animals; Antilymphocyte Serum; Cyclosporine; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Male; Middle Aged; Rabbits; Retrospective Studies; Treatment Outcome; Young Adult | 2011 |
Acute liver failure and aplastic anemia in an 11-year-old girl.
Topics: Acetylcysteine; Anemia, Aplastic; Antilymphocyte Serum; Bilirubin; Child; Cyclosporine; Female; Humans; Immunosuppressive Agents; Liver Failure, Acute; Methylprednisolone Hemisuccinate; Platelet Transfusion; Prednisone; Transaminases; Treatment Outcome; Vitamin K | 2011 |
Relapse of aplastic anemia responsive to sirolimus combined with cyclosporine.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Child; Cyclosporine; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Male; Recurrence; Sirolimus; Treatment Outcome | 2011 |
[Porcine anti-human lymphocyte globulin plus cyclosporine A therapy for severe aplastic anemia].
Topics: Adolescent; Adult; Anemia, Aplastic; Animals; Antilymphocyte Serum; Cyclosporine; Female; Humans; Immunosuppressive Agents; Lymphocytes; Male; Middle Aged; Retrospective Studies; Swine; Treatment Outcome; Young Adult | 2011 |
Immunosuppressive therapy without hematopoietic growth factor exposure in pediatric acquired aplastic anemia.
Topics: Adolescent; Age Factors; Anemia, Aplastic; Child; Child, Preschool; Cyclosporine; Disease-Free Survival; Female; Hematopoietic Cell Growth Factors; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Infant; Male; Retrospective Studies; Survival Rate | 2011 |
Survival after immunosuppressive therapy in children with aplastic anemia.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Child; Cyclosporine; Granulocyte Colony-Stimulating Factor; Humans; Immunologic Factors; Immunosuppressive Agents; India; Treatment Outcome | 2012 |
Renal mucormycosis in aplastic anemia: a novel presentation.
Topics: Acute Kidney Injury; Adult; Amphotericin B; Anemia, Aplastic; Antifungal Agents; Cyclosporine; Humans; Immunosuppressive Agents; Male; Mucormycosis; Renal Dialysis; Steroids; Young Adult | 2013 |
Diagnosis and treatment of acquired aplastic anaemia in adults: 142 cases from a multicentre, prospective cohort study in Shanghai, China.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Androgens; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow; China; Cyclosporine; Diagnosis, Differential; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Kaplan-Meier Estimate; Lymphocyte Count; Male; Middle Aged; Multivariate Analysis; Myelodysplastic Syndromes; Prognosis; Prospective Studies; Reticulocyte Count; Treatment Outcome; Young Adult | 2011 |
Therapy for aplastic anemia.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Drug Therapy, Combination; Humans; Male; Randomized Controlled Trials as Topic; Sirolimus; Tacrolimus; Young Adult | 2011 |
[Effect of cyclosporine on regulatory T cells and Foxp3 in the peripheral blood of children with chronic aplastic anemia].
Topics: Adolescent; Anemia, Aplastic; Child; Child, Preschool; Chronic Disease; Cyclosporine; Female; Forkhead Transcription Factors; Humans; Immunosuppressive Agents; Male; RNA, Messenger; T-Lymphocytes, Regulatory | 2011 |
An Epstein-Barr virus-associated leukemic lymphoma in a patient treated with rabbit antithymocyte globulin and cyclosporine for hepatitis-associated aplastic anemia.
Topics: Acidosis, Lactic; Anemia, Aplastic; Animals; Antilymphocyte Serum; Cyclosporine; DNA, Viral; Epstein-Barr Virus Infections; Fatal Outcome; Humans; Lymphoma, Large B-Cell, Diffuse; Lymphoproliferative Disorders; Male; Middle Aged; Rabbits; Viral Load | 2012 |
Epstein-Barr virus-associated lymphoproliferative disorder developed after anti-thymocyte globulin therapy in a patient with bone marrow failure associated with T-cell large granular lymphocytic leukemia.
Topics: Aged; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow; Bone Marrow Diseases; Bone Marrow Failure Disorders; Cyclosporine; Epstein-Barr Virus Infections; Fatal Outcome; Hemoglobinuria, Paroxysmal; Herpesvirus 4, Human; Humans; Immunosuppressive Agents; Leukemia, Large Granular Lymphocytic; Lymphoproliferative Disorders; Male; Multiple Organ Failure | 2011 |
Unrelated cord blood transplantation for newly diagnosed patients with severe acquired aplastic anemia using a reduced-intensity conditioning: high graft rejection, but good survival.
Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cord Blood Stem Cell Transplantation; Cyclophosphamide; Cyclosporine; Female; Graft Rejection; Humans; Immunosuppressive Agents; Male; Middle Aged; Mycophenolic Acid; Survival Analysis; Transplantation Conditioning; Vidarabine; Young Adult | 2012 |
Immunosuppressive therapy in aplastic anemia.
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Biopsy; Child; Child, Preschool; Cyclosporine; Female; Flow Cytometry; Humans; Immunosuppressive Agents; Kidney Function Tests; Liver Function Tests; Male; Retrospective Studies; Serologic Tests; Treatment Outcome | 2012 |
Antithymocyte globulin and cyclosporine in children with aplastic anemia: a developing country experience.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Developing Countries; Female; Humans; Immunosuppressive Agents; India; Male; Treatment Outcome | 2012 |
[Efficacy of immunosuppressive therapy for children with aplastic anemia].
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Drug Therapy, Combination; Female; Granulocyte Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Male; Retrospective Studies | 2012 |
[Effects of concentration of cyclosporine A on the early response to immunosuppressive therapy in severe aplastic anemia].
Topics: Adolescent; Adult; Anemia, Aplastic; Child; Child, Preschool; Cyclosporine; Female; Humans; Immunosuppressive Agents; Male; Middle Aged; Retrospective Studies; Treatment Outcome; Young Adult | 2011 |
Excellent outcome of matched unrelated donor transplantation in paediatric aplastic anaemia following failure with immunosuppressive therapy: a United Kingdom multicentre retrospective experience.
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Infant; Kaplan-Meier Estimate; Male; Opportunistic Infections; Recurrence; Retrospective Studies; Transplantation Chimera; Transplantation Conditioning; Treatment Failure; Treatment Outcome; Unrelated Donors | 2012 |
Rabbit-antithymocyte globulin combined with cyclosporin A as a first-line therapy: improved, effective, and safe for children with acquired severe aplastic anemia.
Topics: Adolescent; Anemia, Aplastic; Animals; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Female; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Male; Rabbits; Treatment Outcome | 2012 |
[Effects of immunosuppressant therapy on cellular immunity function in patients with aplastic anemia induced by benzene poisoning].
Topics: Adult; Anemia, Aplastic; Benzene; Cyclosporine; Female; Humans; Immunity, Cellular; Immunosuppressive Agents; Male; Middle Aged | 2011 |
[Marked reactive plasmacytosis accompanied by drug eruption in a patient with aplastic anemia].
Topics: Anemia, Aplastic; Cefepime; Cephalosporins; Cyclosporine; Dexamethasone; Diagnosis, Differential; Drug Eruptions; Female; Flow Cytometry; Humans; Meropenem; Middle Aged; Plasma Cells; Thienamycins; Treatment Outcome | 2012 |
[Therapeutic effect of lithium chloride combined with cyclosporine A on mouse model with aplastic anemia].
Topics: Anemia, Aplastic; Animals; Bone Marrow Examination; Cyclosporine; Disease Models, Animal; Drug Therapy, Combination; Female; Lithium Chloride; Mice; Mice, Inbred BALB C; Wnt Signaling Pathway | 2012 |
Successful use of eculizumab in a pediatric patient treated for paroxysmal nocturnal hemoglobinuria.
Topics: Adrenal Cortex Hormones; Anemia, Aplastic; Anemia, Hemolytic; Antibodies, Monoclonal, Humanized; Antilymphocyte Serum; Child; Combined Modality Therapy; Cyclosporine; Erythrocyte Transfusion; Female; Folic Acid; Hematopoietic Cell Growth Factors; Hemoglobinuria, Paroxysmal; Humans; Immunophenotyping; Immunosuppressive Agents; T-Lymphocytes | 2012 |
[Research of regulative factors on CD8(+)HLA-DR(+) effector T cells in severe aplastic anemia].
Topics: Adolescent; Adult; Anemia, Aplastic; CD8-Positive T-Lymphocytes; Cell Proliferation; Cells, Cultured; Child; Cyclosporine; Female; HLA-DR Antigens; Humans; Interleukin-2; Lymphotoxin-alpha; Middle Aged; Receptors, Interleukin-2; Young Adult | 2012 |
Treatment of acquired aplastic anemia in patients with acute liver failure occurring concurrently: a case series.
Topics: Acute Disease; Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Biopsy; Blood Coagulation Tests; Blood Transfusion; Bone Marrow; Child, Preschool; Cyclosporine; Feasibility Studies; Female; Granulocyte Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Liver Failure; Liver Function Tests; Male; T-Lymphocytes; Vitamin K | 2012 |
The efficacy of rabbit antithymocyte globulin with cyclosporine in comparison to horse antithymocyte globulin as a first-line treatment in adult patients with severe aplastic anemia: a single-center retrospective study.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Animals; Antilymphocyte Serum; Clonal Evolution; Cyclosporine; Drug Evaluation; Female; Horses; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Kaplan-Meier Estimate; Lymphocyte Count; Male; Middle Aged; Rabbits; Recurrence; Republic of Korea; Retrospective Studies; Species Specificity; T-Lymphocytes; Treatment Outcome; Young Adult | 2013 |
The progression risk factors of children with transfusion-independent non-severe aplastic anemia.
Topics: Adolescent; Anemia, Aplastic; Blood Transfusion; Child; Child, Preschool; Cyclosporine; Disease Progression; Female; Follow-Up Studies; Humans; Infant; Male; Palliative Care; Prognosis; Retrospective Studies; Risk Factors; Stanozolol | 2013 |
Rabbit antithymocyte globulin and cyclosporine as first-line therapy for children with acquired aplastic anemia.
Topics: Adolescent; Anemia, Aplastic; Animals; Antilymphocyte Serum; Asian People; Child; Child, Preschool; Cyclosporine; Disease-Free Survival; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Infant; Japan; Male; Rabbits; Retrospective Studies; Survival Rate | 2013 |
Eczema herpeticum with herpetic folliculitis after bone marrow transplant under prophylactic acyclovir: are patients with underlying dermatologic disorders at higher risk?
Topics: Acyclovir; Adult; Anemia, Aplastic; Antiviral Agents; Bone Marrow Transplantation; Cyclosporine; Dermatitis, Atopic; Female; Folliculitis; Herpes Simplex; Herpesvirus 1, Human; Humans; Kaposi Varicelliform Eruption; Risk Factors | 2013 |
A retrospective analysis of long-term survival in severe aplastic anemia patients treated with allogeneic bone marrow transplantation or immunosuppressive therapy with antithymocyte globulin and cyclosporin A at a single institution.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Transplantation; Child; Cyclosporine; Female; Graft vs Host Disease; Humans; Immunosuppressive Agents; Lymphoproliferative Disorders; Male; Middle Aged; Retrospective Studies; Survival Analysis; Time Factors; Transplantation, Homologous; Treatment Outcome | 2002 |
[Combination of mycophenolate mofetil with cyclosporine A and methotrexate for the prophylaxes of acute graft versus host disease in allogeneic peripheral stem cell transplantation].
Topics: Acute Disease; Adult; Anemia, Aplastic; Blood Platelets; Chronic Disease; Cyclosporine; Drug Therapy, Combination; Female; Follow-Up Studies; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Incidence; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Mouth Mucosa; Mycophenolic Acid; Neutrophils; Transplantation, Homologous; Treatment Outcome | 2002 |
Cardiac surgery in a patient with paroxysmal nocturnal hemoglobinuria.
Topics: Aged; Anemia, Aplastic; Anemia, Hemolytic; Aortic Valve Insufficiency; Cardiopulmonary Bypass; Complement Activation; Coronary Stenosis; Cyclosporine; Granulocyte Colony-Stimulating Factor; Heart Valve Prosthesis Implantation; Hemoglobinuria, Paroxysmal; Humans; Hypertension; Immunosuppressive Agents; Internal Mammary-Coronary Artery Anastomosis; Kidney Failure, Chronic; Male; Postoperative Complications; Preoperative Care; Risk; Thrombophilia; Thrombosis | 2002 |
HLA-DR15 (DR2) is overrepresented in myelodysplastic syndrome and aplastic anemia and predicts a response to immunosuppression in myelodysplastic syndrome.
Topics: Adult; Anemia, Aplastic; Antilymphocyte Serum; Cohort Studies; Cyclosporine; HLA-DR Antigens; HLA-DR Serological Subtypes; HLA-DR2 Antigen; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Middle Aged; Myelodysplastic Syndromes; Prognosis | 2002 |
Iatrogenesis or bad luck? relapse of an LMP1-positive follicular lymphoma after immunosuppression for hepatitis-associated aplastic anaemia.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Fatal Outcome; Hepatitis, Viral, Human; Herpesvirus 4, Human; Humans; Iatrogenic Disease; Immunosuppression Therapy; Lymphoma, Follicular; Male; Middle Aged; Recurrence; Skin Neoplasms; Viral Matrix Proteins; Virus Activation | 2002 |
Enhanced response to basiliximab in a patient with aplastic anemia after treatment with standard immunosuppression.
Topics: Acute Disease; Adult; Anemia, Aplastic; Antibodies, Monoclonal; Antilymphocyte Serum; Basiliximab; Cyclosporine; Drug Therapy, Combination; Hepatitis; Humans; Immunosuppressive Agents; Male; Mycophenolic Acid; Recombinant Fusion Proteins; Remission Induction; T-Lymphocytes | 2002 |
Chronic lymphocytic leukemia presenting in association with aplastic anemia.
Topics: Adrenal Cortex Hormones; Aged; Anemia, Aplastic; Antineoplastic Agents; Biopsy; Bone Marrow; Cyclosporine; Fatal Outcome; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell | 2002 |
Cyclosporine-induced reversible pure motor spastic paraparesis in a patient with aplastic anaemia.
Topics: Adolescent; Anemia, Aplastic; Cyclosporine; Dose-Response Relationship, Drug; Follow-Up Studies; Humans; Male; Paraparesis, Spastic; Risk Assessment; Severity of Illness Index | 2002 |
[Time course changes in the count of peripheral granulocytes in children with acquired aplastic anemias treated with antithymocyte globulin, cyclosporin A and granulocytic colony stimulating factor].
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Data Interpretation, Statistical; Drug Therapy, Combination; Female; Granulocyte Colony-Stimulating Factor; Granulocytes; Humans; Immunosuppressive Agents; Leukocyte Count; Male; Software; Time Factors | 2002 |
Severe aplastic anemia with autoimmune thyroiditis showing no hematological response to intensive immunosuppressive therapy.
Topics: Adult; Anemia, Aplastic; Antilymphocyte Serum; Autoantibodies; CD3 Complex; CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Complementarity Determining Regions; Cyclosporine; Female; Flow Cytometry; Hematopoiesis; Humans; Immunosuppressive Agents; Lymphocyte Subsets; Receptors, Antigen, T-Cell, alpha-beta; T-Lymphocytes; Thyroiditis, Autoimmune; Treatment Failure | 2003 |
Merkel cell carcinoma developing after antithymocyte globulin and cyclosporine therapy for aplastic anemia.
Topics: Aged; Anemia, Aplastic; Antilymphocyte Serum; Carcinoma, Merkel Cell; Cyclosporine; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents | 2003 |
Induction of complete remission of hypoplastic leukemia with antithymocyte globulin.
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Apoptosis; Bone Marrow Examination; Cyclosporine; Diagnosis, Differential; Etoposide; Humans; Leukemia; Male; Pancytopenia; Recurrence; Remission Induction | 2003 |
Very severe aplastic anemia appearing after thymectomy.
Topics: Anemia, Aplastic; Biopsy, Needle; Bone Marrow; Cyclosporine; Drug Therapy, Combination; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Middle Aged; Rare Diseases; Risk Assessment; Severity of Illness Index; Thymectomy; Thymoma; Treatment Outcome | 2003 |
[Development of severe aplastic anemia in a girl with Hashimoto's thyroiditis and papillary thyroid carcinoma].
Topics: Adolescent; Anemia, Aplastic; Autoimmunity; Carcinoma, Papillary; Cyclosporine; Female; Humans; Lymph Node Excision; Severity of Illness Index; Thyroid Neoplasms; Thyroidectomy; Thyroiditis, Autoimmune | 2003 |
Ulcerative colitis associated with aplastic anemia.
Topics: Adult; Anemia, Aplastic; Anti-Inflammatory Agents; Blood Transfusion; Bone Marrow Examination; Colitis, Ulcerative; Cyclosporine; Humans; Immunosuppressive Agents; Male; Mesalamine; Prednisolone; Remission Induction; Treatment Outcome | 2003 |
Cytomegalovirus infection in a patient with rheumatoid arthritis.
Topics: Anemia, Aplastic; Antiviral Agents; Arthritis, Rheumatoid; Cyclosporine; Cytomegalovirus; Cytomegalovirus Infections; Female; Ganciclovir; Humans; Immunocompromised Host; Immunosuppressive Agents; Methotrexate; Middle Aged; Pneumonia, Viral; RNA, Viral; Treatment Outcome | 2003 |
Aplastic anemia complicating systemic lupus erythematosus: successful management with cyclosporine.
Topics: Adult; Anemia, Aplastic; Cyclophosphamide; Cyclosporine; Female; Humans; Lupus Erythematosus, Systemic; Menorrhagia; Methylprednisolone; Pancytopenia; Phenytoin; Seizures; Treatment Outcome | 2004 |
Littoral cell angioma of the spleen in a patient with severe aplastic anaemia.
Topics: Anemia, Aplastic; Animals; Antilymphocyte Serum; Blood Transfusion; Cyclosporine; Female; Hemangioma; Horses; Humans; Hypersplenism; Immunosuppressive Agents; Middle Aged; Oxymetholone; Rabbits; Splenectomy; Splenic Neoplasms; T-Lymphocytes | 2003 |
Long-term outcome after bone marrow transplantation for severe aplastic anemia.
Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Transplantation; Combined Modality Therapy; Cyclosporine; Female; Follow-Up Studies; Humans; Incidence; Infections; Male; Neoplasms, Second Primary; Retrospective Studies; Survival Analysis; Time Factors; Tissue Donors; Treatment Outcome; Whole-Body Irradiation | 2004 |
[Acquired aplastic anemia of the adult. Treatment of 2 cases].
Topics: Aged; Anemia, Aplastic; Antilymphocyte Serum; Combined Modality Therapy; Cyclosporine; Humans; Immunosuppressive Agents; Male; Middle Aged | 2003 |
Restoration of immunity and reactivation of hepatitis B virus after immunosuppressive therapy in a patient with severe aplastic anaemia.
Topics: Adult; Anemia, Aplastic; Antilymphocyte Serum; Antiviral Agents; Carrier State; Cyclosporine; Hepatitis B, Chronic; Humans; Immunosuppressive Agents; Lamivudine; Male; Recurrence | 2004 |
[Immunosuppressive-associated encephalopathy in bone marrow transplant recipients].
Topics: Acute Disease; Adolescent; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Brain Diseases; Cyclosporine; Female; Humans; Immunosuppressive Agents; Leukemia; Male; Middle Aged; Myelodysplastic Syndromes; Tacrolimus | 2004 |
Th1/Th2 lymphocyte balance in patients with aplastic anemia.
Topics: Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Biomarkers; CD4 Lymphocyte Count; Cyclosporine; Female; Granulocyte Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Interferon-gamma; Interleukin-4; Lenograstim; Male; Middle Aged; Recombinant Proteins; Th1 Cells; Th2 Cells; Treatment Outcome | 2004 |
Successful treatment of severe aplastic anemia in children using standardized immunosuppressive therapy with antithymocyte globulin and cyclosporine A.
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Drug Therapy, Combination; Glucocorticoids; Hepatitis, Viral, Human; Humans; Immunosuppressive Agents; Infant; Retrospective Studies; Treatment Outcome | 2004 |
Gilbert syndrome as differential diagnosis of hyperbilirubinemia in acquired aplastic anemia.
Topics: Adolescent; Anemia, Aplastic; Child, Preschool; Cyclosporine; Diagnosis, Differential; Gilbert Disease; Humans; Hyperbilirubinemia; Male | 2005 |
[Bone marrow aplasia during hemodialysis successfully treated with cyclosporine. Report of one case].
Topics: Adult; Anemia, Aplastic; Cyclosporine; Glomerulonephritis, IGA; Humans; Immunosuppressive Agents; Kidney Transplantation; Male; Pancytopenia; Renal Dialysis | 2004 |
A mouse model of lymphocyte infusion-induced bone marrow failure.
Topics: Anemia, Aplastic; Animals; Antibodies, Monoclonal; Antilymphocyte Serum; Bone Marrow; Bone Marrow Transplantation; Colony-Forming Units Assay; Cyclosporine; Disease Models, Animal; Gamma Rays; Hematopoiesis; Hematopoietic Stem Cells; Immunosuppressive Agents; Interferon-gamma; Lymph Nodes; Lymphocyte Transfusion; Mice; Pancytopenia; Receptors, Antigen, T-Cell, alpha-beta; T-Lymphocytes | 2004 |
A case of focal segmental glomerulosclerosis associated with aplastic anemia.
Topics: Adult; Anemia, Aplastic; Cyclosporine; Female; Glomerulosclerosis, Focal Segmental; Humans; Immunosuppressive Agents; Prednisone; Rare Diseases; Treatment Outcome | 2004 |
Non-total body irradiation containing preparative regimen in alternative donor bone marrow transplantation for severe aplastic anemia.
Topics: Adolescent; Adult; Anemia, Aplastic; Blood Transfusion; Bone Marrow Transplantation; Cyclophosphamide; Cyclosporine; Female; Graft vs Host Disease; Histocompatibility; Histocompatibility Testing; Humans; Immunosuppressive Agents; Male; Methotrexate; T-Lymphocytes; Time Factors; Transplantation Conditioning; Treatment Outcome; Vidarabine; Whole-Body Irradiation | 2005 |
Expression of interferon-gamma and tumor necrosis factor-alpha in bone marrow T cells and their levels in bone marrow plasma in patients with aplastic anemia.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow; Case-Control Studies; CD3 Complex; Child; Cyclosporine; Female; Follow-Up Studies; Humans; Immunity, Cellular; Interferon-gamma; Male; Middle Aged; Remission Induction; T-Lymphocytes; Tumor Necrosis Factor-alpha | 2005 |
Withdrawal of immunosuppression contributing to the remission of malignant melanoma: a case report.
Topics: Anemia, Aplastic; Cyclosporine; Female; Humans; Immunosuppressive Agents; Male; Melanoma; Remission Induction; Sirolimus; Tacrolimus | 2005 |
Immunosuppression with ALG and CsA is first line treatment in children with SAA lacking an HLA identical sibling.
Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Child; Cyclosporine; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Survival Rate | 2005 |
Antigen-recognition sites of micromanipulated T cells in patients with acquired aplastic anemia.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Female; Gene Rearrangement, T-Lymphocyte; Humans; Immunosuppressive Agents; Male; Middle Aged; Reference Values; T-Lymphocytes | 2005 |
Severe aplastic anemia associated with paroxysmal nocturnal hemoglobinuria and lymphoplasmacytic lymphoma.
Topics: Aged; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Neoplasms; Cyclosporine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Fatal Outcome; Hemoglobinuria, Paroxysmal; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Time Factors; Waldenstrom Macroglobulinemia | 2005 |
Cyclophosphamide and antithymocyte globulin as a conditioning regimen for allogeneic marrow transplantation in patients with aplastic anaemia: a long-term follow-up.
Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cyclophosphamide; Cyclosporine; Female; Follow-Up Studies; Graft vs Host Disease; Humans; Immunosuppressive Agents; Karnofsky Performance Status; Male; Methotrexate; Middle Aged; Multivariate Analysis; Survival Rate; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome | 2005 |
Minor population of CD55-CD59- blood cells predicts response to immunosuppressive therapy and prognosis in patients with aplastic anemia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia, Aplastic; Antigens, CD; Antilymphocyte Serum; CD55 Antigens; CD59 Antigens; Chromosome Aberrations; Cyclosporine; Female; Flow Cytometry; Granulocytes; Humans; Immunosuppressive Agents; Leukocyte Count; Male; Middle Aged; Predictive Value of Tests; Survival Analysis | 2006 |
Acute myeloid leukemia after intensive immunosuppressive therapy in aplastic anemia.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Child; Cyclosporine; Humans; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Male | 2005 |
Aplastic anemia: management of adult patients.
Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Bone Transplantation; Child; Cyclosporine; Female; Hepatitis; Humans; Immunosuppressive Agents; Incidence; Middle Aged; Patient Selection; Pregnancy; Pregnancy Complications; Recurrence; Salvage Therapy; Severity of Illness Index; Transplantation, Homologous; Young Adult | 2005 |
[Myelodysplastic syndrome with der (1;7) transformed from aplastic anemia 42 years after onset].
Topics: Anemia, Aplastic; Blood Transfusion; Bone Marrow Examination; Chromosomes, Human, Pair 7; Cyclosporine; Humans; Immunosuppressive Agents; Male; Middle Aged; Monosomy; Myelodysplastic Syndromes; Severity of Illness Index; Time Factors | 2005 |
Allografting in patients with severe, refractory aplastic anemia using peripheral blood stem cells and a fludarabine-based conditioning regimen: the Mexican experience.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Busulfan; Child; Child, Preschool; Cyclophosphamide; Cyclosporine; Disease-Free Survival; Female; Graft Rejection; Graft Survival; Graft vs Host Disease; Humans; Male; Mexico; Middle Aged; Myeloablative Agonists; Peripheral Blood Stem Cell Transplantation; Remission Induction; Retrospective Studies; Transplantation Conditioning; Transplantation, Homologous; Vidarabine | 2006 |
[Aplastic anemia as onset manifestation pulmonary sarcoidosis].
Topics: Adrenal Cortex Hormones; Adult; Anemia, Aplastic; Antilymphocyte Serum; Biopsy; Colony-Stimulating Factors; Cyclosporine; Female; Humans; Immunosuppressive Agents; Lung; Radiography, Thoracic; Sarcoidosis, Pulmonary; Tomography, X-Ray Computed | 2006 |
[Immunotherapy in aplastic anaemia as a cause of reactivation of hepatitis B virus-immunologic aspects].
Topics: Anemia, Aplastic; Antigens, CD; Antiviral Agents; Child; Combined Modality Therapy; Cyclosporine; Hepatitis B, Chronic; Humans; Immunosuppressive Agents; Immunotherapy; Interferon-alpha; Lamivudine; Male; Reverse Transcriptase Inhibitors | 2005 |
Successful treatment with allogeneic peripheral blood stem cell transplantation and granulocyte transfusion for severe aplastic anemia with sinusitis.
Topics: Adult; Anemia, Aplastic; Blood Transfusion, Autologous; Cyclosporine; Female; Granulocytes; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Recurrence; Sinusitis; Transplantation, Homologous; Treatment Outcome | 2006 |
[Aplastic anemia and pure red cell aplasia: diagnosis and treatment].
Topics: Algorithms; Anemia, Aplastic; Bone Marrow Transplantation; Cyclosporine; Erythropoietin; Humans; Red-Cell Aplasia, Pure; Severity of Illness Index | 2006 |
Retreatment with rabbit anti-thymocyte globulin and ciclosporin for patients with relapsed or refractory severe aplastic anaemia.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Animals; Antilymphocyte Serum; Child; Combined Modality Therapy; Cyclosporine; Female; Humans; Immunosuppressive Agents; Male; Middle Aged; Rabbits; Recurrence; Retrospective Studies; Survival Analysis; Treatment Failure; Treatment Outcome | 2006 |
Clinical observation on treatment of chronic aplastic anemia by Shengxuening and cyclosporin A.
Topics: Adult; Aged; Androgens; Anemia, Aplastic; Chronic Disease; Cyclosporine; Drugs, Chinese Herbal; Erythroid Precursor Cells; Follow-Up Studies; Hemoglobins; Humans; Medicine, Chinese Traditional; Middle Aged; Neutrophils; Platelet Count; Reticulocytes; Stanozolol; Tablets | 2006 |
Treatment for children with severe aplastic anemia and sickle cell disease in low income countries in Latin America: a report on the recent meetings of the Monza International School of Pediatric Hematology/Oncology (MISPHO): Part III.
Topics: Anemia, Aplastic; Anemia, Sickle Cell; Antilymphocyte Serum; Child; Cyclosporine; Developing Countries; Humans; Hydroxyurea; International Cooperation; Latin America | 2007 |
Preceding immunosuppressive therapy with antithymocyte globulin and ciclosporin increases the incidence of graft rejection in children with aplastic anaemia who underwent allogeneic bone marrow transplantation from HLA-identical siblings.
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Antineoplastic Agents; Bone Marrow Transplantation; Child; Child, Preschool; Cyclosporine; Female; Graft Rejection; Humans; Incidence; Infant; Infant, Newborn; Male; Risk Factors; Siblings; Statistics, Nonparametric; Survival Rate; Transplantation Conditioning; Transplantation, Isogeneic; Treatment Failure | 2006 |
Granulocyte-stimulating factor and severe aplastic anemia: a survey by the European Group for Blood and Marrow Transplantation (EBMT).
Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Data Collection; Europe; Female; Granulocyte Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Male; Middle Aged; Myelodysplastic Syndromes; Recombinant Proteins; Risk Factors | 2007 |
Comparable outcomes of matched-related and alternative donor stem cell transplantation for pediatric severe aplastic anemia.
Topics: Adolescent; Alemtuzumab; Anemia, Aplastic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neoplasm; Antilymphocyte Serum; Bone Marrow Transplantation; Child; Child, Preschool; Cyclosporine; Female; Graft Survival; Graft vs Host Disease; Histocompatibility; Humans; Immunosuppressive Agents; Infant; Infections; Kaplan-Meier Estimate; Male; Methotrexate; Peripheral Blood Stem Cell Transplantation; Postoperative Complications; Retrospective Studies; Siblings; Survival Analysis; T-Lymphocyte Subsets; Tacrolimus; Tissue Donors; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Whole-Body Irradiation | 2006 |
The influence of cyclosporin alone, or cyclosporin and methotrexate, on the incidence of mixed haematopoietic chimaerism following allogeneic sibling bone marrow transplantation for severe aplastic anaemia.
Topics: Adolescent; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Child; Cyclosporine; Female; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Histocompatibility Testing; Humans; Immunosuppressive Agents; Male; Methotrexate; Randomized Controlled Trials as Topic; Siblings; Transplantation Chimera; Transplantation, Homologous | 2007 |
[Diagnosis and treatment of aquired aplastic anemia].
Topics: Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Transplantation; Combined Modality Therapy; Cyclosporine; Female; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Male; Treatment Outcome | 2006 |
Roles of DRB1 *1501 and DRB1 *1502 in the pathogenesis of aplastic anemia.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anemia, Aplastic; Antilymphocyte Serum; Blood Cells; Child; Cyclosporine; Drug Therapy, Combination; Female; Hemoglobinuria, Paroxysmal; HLA-DR Antigens; HLA-DR Serological Subtypes; HLA-DRB1 Chains; Humans; Male; Middle Aged; Treatment Outcome | 2007 |
Aplastic anaemia as an autoimmune complication of thymoma.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Antineoplastic Agents; Bone Marrow Examination; Cyclosporine; Fatal Outcome; Female; Humans; Lymphocyte Subsets; Middle Aged; Mycophenolic Acid; Thymectomy; Thymoma | 2007 |
Minor antigen h60-mediated aplastic anemia is ameliorated by immunosuppression and the infusion of regulatory T cells.
Topics: Anemia, Aplastic; Animals; Blood Cell Count; Bone Marrow; CD4 Antigens; CD8-Positive T-Lymphocytes; Cyclosporine; Immunosuppression Therapy; Immunosuppressive Agents; Interleukin-2 Receptor alpha Subunit; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Minor Histocompatibility Antigens; Pancytopenia; T-Lymphocytes, Regulatory | 2007 |
Prolonged renal failure secondary to antithymocyte globulin treatment in severe aplastic anemia.
Topics: Acute Kidney Injury; Adult; Anemia, Aplastic; Antilymphocyte Serum; Anuria; Blood Urea Nitrogen; Creatinine; Cyclosporine; Humans; Immunosuppressive Agents; Male; Renal Dialysis | 2007 |
Cutaneous Kaposi sarcoma which developed in a patient with aplastic anaemia using immunosuppressive therapy--description of the first adult case.
Topics: Anemia, Aplastic; Antineoplastic Agents, Phytogenic; Cyclosporine; Humans; Immunosuppressive Agents; Male; Middle Aged; Sarcoma, Kaposi; Skin Neoplasms; Vincristine | 2007 |
Cyclosporine therapy for acquired aplastic anemia: predictive factors for the response and long-term prognosis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia, Aplastic; Cyclosporine; Female; Humans; Immunosuppressive Agents; Japan; Male; Middle Aged; Prognosis; Retrospective Studies; Survival Analysis; Survivors | 2007 |
Epstein-Barr virus associated pneumonia in an adult patient with severe aplastic anaemia: resolution after the transient withdrawal of cyclosporine.
Topics: Adult; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Epstein-Barr Virus Infections; Herpesvirus 4, Human; Humans; Immunocompromised Host; Immunosuppressive Agents; Male; Pneumonia, Viral; Remission Induction; T-Lymphocytes; Viremia; Virus Activation | 2007 |
Outcome of children with aplastic anemia treated with immunosuppressive therapy.
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Female; Granulocyte Colony-Stimulating Factor; Humans; Hypertension; Immunosuppressive Agents; Infant; Male; Prednisone; Survival Rate | 2008 |
Umbilical-cord blood cell transplantation conditioned with a reduced intensity-regimen is a practical salvage therapy for severe aplastic anemia refractory to immunosuppressive therapy with antithymocyte globulin/ciclosporin.
Topics: Adult; Anemia, Aplastic; Antilymphocyte Serum; Cord Blood Stem Cell Transplantation; Cyclosporine; Female; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Male; Salvage Therapy; Transplantation Conditioning | 2007 |
[Expression of HLA-DRB1*15 genotype in children with acquired aplastic anemia and its relation to effect of immunosuppressive therapy].
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Female; Genotype; HLA-DR Antigens; HLA-DRB1 Chains; Humans; Immunosuppressive Agents; Male | 2007 |
Cyclosporine induced neurotoxicity in a stem cell transplant recipient.
Topics: Adult; Anemia, Aplastic; Cyclosporine; Female; Humans; Immunosuppressive Agents; Neurotoxicity Syndromes; Stem Cell Transplantation; Stem Cells; Transplantation; Transplantation, Homologous | 2007 |
Cyclosporin A response and dependence in children with acquired aplastic anaemia: a multicentre retrospective study with long-term observation follow-up.
Topics: Adolescent; Anemia, Aplastic; Child; Child, Preschool; Cyclosporine; Disease Progression; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Epidemiologic Methods; Female; Granulocyte Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Infant; Male; Recurrence; Treatment Outcome | 2008 |
[Clinical implications of combined measurement bone marrow T cells intracellular IFNgamma and HLA-DRB1*1501 measurement in predicting the response to immunosuppressive therapy for aplastic anemia].
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Bone Marrow Cells; CD8-Positive T-Lymphocytes; Child; Cyclosporine; Female; Flow Cytometry; HLA-DR Antigens; HLA-DRB1 Chains; Humans; Immunosuppressive Agents; Interferon-gamma; Logistic Models; Male; Middle Aged; Polymerase Chain Reaction; Predictive Value of Tests; Treatment Outcome | 2007 |
[Treatment of acquired severe aplastic anemia in pediatric patients with immunosuppression and allogeneic stem cell hematopoietic transplant].
Topics: Adolescent; Anemia, Aplastic; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cyclosporine; Female; Follow-Up Studies; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Male; Methylprednisolone; Prognosis; Risk Factors; Severity of Illness Index; Transplantation, Homologous; Treatment Outcome | 2007 |
Antithymocyte globulin and cyclosporin in children with acquired aplastic anemia.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Child; Cyclosporine; Female; Humans; Immunosuppressive Agents; Male; Recurrence; Treatment Outcome | 2008 |
[Evaluation of a prospective therapeutic protocol in adult patients with nonsevere aplastic anemia in South Tunisia].
Topics: Administration, Oral; Adult; Aged; Androgens; Anemia, Aplastic; Anti-Bacterial Agents; Blood Transfusion; Clinical Protocols; Cyclosporine; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Kaplan-Meier Estimate; Male; Middle Aged; Prognosis; Prospective Studies; Time Factors; Treatment Outcome | 2008 |
Sustained trilineage response in a patient with ALG-resistant severe aplastic anaemia after treatment with G-CSF, erythropoietin and cyclosporin A: association of recovery with marked elevation of serum alkaline phosphatase.
Topics: Adolescent; Alkaline Phosphatase; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Drug Resistance; Drug Therapy, Combination; Erythropoietin; Female; Granulocyte Colony-Stimulating Factor; Humans; Prednisolone | 1993 |
Haematological improvement by long-term administration of recombinant human granulocyte-colony stimulating factor and recombinant human erythropoietin in a patient with severe aplastic anaemia.
Topics: Anemia, Aplastic; Bone Marrow; Child; Cyclosporine; Erythropoietin; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cells; Hemoglobins; Humans; Leukocyte Count; Platelet Count; Recombinant Proteins; Reticulocyte Count; Time Factors | 1994 |
Quality of hematologic recovery in patients with aplastic anemia following cyclosporine therapy.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antigens, CD; CD55 Antigens; CD59 Antigens; Clone Cells; Cyclosporine; Female; Flow Cytometry; Glycosylphosphatidylinositols; Hematopoiesis; Humans; Male; Membrane Glycoproteins; Middle Aged; Neutrophils; Receptors, IgG | 1995 |
Acute hemolysis during cyclosporine therapy successfully treated with vitamin E.
Topics: Acute Disease; Adolescent; Anemia, Aplastic; Anemia, Hemolytic; Bone Marrow Transplantation; Cyclosporine; Humans; Immunosuppressive Agents; Male; Vitamin E | 1995 |
Immune suppression therapy in aplastic anemia: influencing factors on response and survival.
Topics: Adolescent; Adult; Age Factors; Aged; Androgens; Anemia, Aplastic; Antilymphocyte Serum; Blood Cell Count; Blood Transfusion; Child; Child, Preschool; Cyclosporine; Female; Humans; Immunosuppression Therapy; Infant; Life Tables; Male; Middle Aged; Multivariate Analysis; Pregnancy; Pregnancy Complications, Hematologic; Prognosis; Retrospective Studies; Survival Analysis; Treatment Outcome | 1995 |
[Mechanism of immunosuppressive therapy for aplastic anemia].
Topics: Adult; Anemia, Aplastic; Antilymphocyte Serum; CD4-CD8 Ratio; Cyclosporine; Female; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Male; Middle Aged | 1993 |
Collection of peripheral blood hematopoietic progenitors (PBHP) from patients with severe aplastic anemia (SAA) after prolonged administration of granulocyte colony-stimulating factor.
Topics: Adolescent; Adult; Anemia, Aplastic; Antigens, CD; Antigens, Surface; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Lymphocyte Depletion; Male; Middle Aged; Phenotype; T-Lymphocytes; Time Factors | 1993 |
Establishment of a CD4+ T cell clone recognizing autologous hematopoietic progenitor cells from a patient with immune-mediated aplastic anemia.
Topics: Adult; Anemia, Aplastic; Autoimmune Diseases; Bone Marrow; CD4-Positive T-Lymphocytes; Cells, Cultured; Clone Cells; Cyclosporine; Cytotoxicity, Immunologic; Gene Rearrangement, beta-Chain T-Cell Antigen Receptor; Hematopoietic Stem Cells; Humans; Interferon-gamma; Male; Receptors, Antigen, T-Cell | 1995 |
[Bone marrow aplasia and gold salts. Review of the literature apropos of 2 cases].
Topics: Anemia, Aplastic; Antilymphocyte Serum; Arthritis, Rheumatoid; Cyclosporine; Female; Gold Sodium Thiomalate; Humans; Male; Methylprednisolone; Middle Aged; Prednisone | 1994 |
Is cyclosporin neurotoxicity enhanced in the presence of liposomal amphotericin B?
Topics: Adult; Amphotericin B; Anemia, Aplastic; Cyclosporine; Drug Interactions; Humans; Liposomes; Male; Myoclonus; Tremor | 1994 |
Identification of a specific HLA class II haplotype strongly associated with susceptibility to cyclosporine-dependent aplastic anemia.
Topics: Adolescent; Adult; Aged; Alleles; Anemia, Aplastic; Autoimmune Diseases; Cyclosporine; Female; Genes, MHC Class II; Genetic Predisposition to Disease; Haplotypes; HLA-DQ alpha-Chains; HLA-DQ Antigens; HLA-DQ beta-Chains; HLA-DR Antigens; HLA-DRB1 Chains; Humans; Incidence; Japan; Male; Middle Aged; Polymorphism, Single-Stranded Conformational; Recurrence; Remission Induction | 1994 |
Risk factors for acute graft-versus-host disease in 325 consecutive bone marrow recipients.
Topics: Adolescent; Adult; Age Factors; Analysis of Variance; Anemia, Aplastic; Bone Marrow Transplantation; Child; Child, Preschool; Cyclosporine; Cytomegalovirus Infections; Drug Therapy, Combination; Graft vs Host Disease; Herpesviridae Infections; Histocompatibility Testing; Humans; Infant; Leukemia; Lymphocyte Depletion; Methotrexate; Middle Aged; Multivariate Analysis; Regression Analysis; Risk Factors; Transplantation, Homologous | 1994 |
Bone marrow transplantation in Thailand.
Topics: Anemia, Aplastic; Blood Transfusion; Bone Marrow Transplantation; Cyclosporine; Fetal Blood; Graft vs Host Disease; Histocompatibility Testing; Humans; Incidence; Leukemia; Methotrexate; Thailand; Thalassemia; Transplantation, Homologous | 1994 |
Circulating erythropoietin levels in pathophysiological conditions.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Arthritis, Rheumatoid; Biomarkers; Cyclosporine; Enzyme-Linked Immunosorbent Assay; Erythropoietin; Hematocrit; Humans; Middle Aged | 1994 |
Graft rejection and second bone marrow transplants for acquired aplastic anaemia: a report from the Aplastic Anaemia Working Party of the European Bone Marrow Transplant Group.
Topics: Adolescent; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Child; Cyclosporine; Europe; Female; Graft Rejection; Humans; Male; Prognosis; Registries; Time Factors | 1994 |
[Two cases of aplastic anemia with hand tremor during treatment with cyclosporin A].
Topics: Adolescent; Adult; Anemia, Aplastic; Cyclosporine; Hand; Humans; Magnesium; Magnesium Deficiency; Male; Tremor | 1993 |
Successful use of isotretinoin in a patient on cyclosporine: apparent lack of toxicity.
Topics: Acne Vulgaris; Adolescent; Anemia, Aplastic; Cyclosporine; Drug Interactions; Drug Tolerance; Female; Humans; Isotretinoin | 1993 |
BMT for severe aplastic anemia using cyclosporine.
Topics: Adolescent; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cyclosporine; Female; Graft Rejection; Graft Survival; Graft vs Host Disease; Humans; Male; Middle Aged; Survival Rate | 1993 |
[Immunomodulating treatment of severe aplastic anemia in adults].
Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Transplantation; Cyclosporine; Female; Humans; Male; Prognosis; T-Lymphocytes; Treatment Outcome | 1993 |
Bone marrow transplantation for pediatric patients with severe aplastic anemia in Taiwan.
Topics: Adolescent; Anemia, Aplastic; Bone Marrow Transplantation; Child; Cyclophosphamide; Cyclosporine; Female; Graft Rejection; Graft vs Host Disease; Humans; Male; Taiwan | 1993 |
Bone marrow transplantation from unrelated donors: the Italian experience. GITMO, AIEOP and IBMDR.
Topics: Adolescent; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Child; Child, Preschool; Cyclosporine; Graft vs Host Disease; Histocompatibility; HLA Antigens; Humans; Infant; Italy; Leukemia; Methotrexate; Middle Aged; Tissue Donors; Transplantation, Homologous | 1993 |
Granulocyte-macrophage colony-stimulating factor in the sera of patients with aplastic anemia.
Topics: Adult; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Enzyme-Linked Immunosorbent Assay; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Lymphocyte Activation; Male; Methylprednisolone; Middle Aged; T-Lymphocytes | 1993 |
Analysis of lymphocyte subsets in patients with aplastic anemia before and during immunosuppressive therapy.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow; CD4-CD8 Ratio; Cyclosporine; Fluorescent Antibody Technique; Humans; Immunosuppression Therapy; Methylprednisolone; Receptors, Antigen, T-Cell; T-Lymphocyte Subsets; T-Lymphocytes, Cytotoxic; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory | 1993 |
Treatment of aplastic anemia with a monoclonal antibody directed against the interleukin-2 receptor.
Topics: Adult; Anemia, Aplastic; Antibodies, Monoclonal; Cyclosporine; Female; Humans; Injections, Intravenous; Methylprednisolone; Receptors, Interleukin-2; Recurrence | 1993 |
Genetic defects underlying paroxysmal nocturnal hemoglobinuria that arises out of aplastic anemia.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Base Sequence; Cyclosporine; DNA Mutational Analysis; Hemoglobinuria, Paroxysmal; Humans; Immunosuppressive Agents; Membrane Proteins; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; RNA Splicing; RNA, Messenger; Sequence Deletion; T-Lymphocytes | 1995 |
Interaction between cyclosporine and danazol in a pediatric patient.
Topics: Anemia, Aplastic; Child; Cyclosporine; Danazol; Drug Interactions; Estrogen Antagonists; Humans; Immunosuppressive Agents; Male | 1996 |
Response to immunosuppressive therapy and an HLA-DRB1 allele in patients with aplastic anaemia: HLA-DRB1*1501 does not predict response to antithymocyte globulin.
Topics: Adolescent; Adult; Aged; Alleles; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Female; HLA-DR Antigens; HLA-DRB1 Chains; Humans; Infant; Male; Middle Aged; Retrospective Studies; T-Lymphocytes; Treatment Outcome | 1996 |
Relative erythroid hyperplasia in the bone marrow at diagnosis of aplastic anaemia: a predictive marker for a favourable response to cyclosporine therapy.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Bone Marrow; Cyclosporine; Erythroblasts; Female; Humans; Hyperplasia; Male; Middle Aged; Multivariate Analysis; Patient Selection; Retrospective Studies; Treatment Outcome | 1996 |
Correction of aplastic anaemia complicating paroxysmal nocturnal haemoglobinuria: absence of eradication of the PNH clone and dependence of response on cyclosporin A administration.
Topics: Adult; Anemia, Aplastic; Cyclosporine; Female; Hemoglobinuria, Paroxysmal; Humans; Immunosuppression Therapy; Male; Time Factors | 1996 |
First report of a B cell lymphoproliferative disorder arising in a patient treated with immune suppressants for severe aplastic anemia.
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; B-Lymphocytes; Cyclosporine; Female; Humans; Immunosuppressive Agents; Leukocyte Count; Lymphoproliferative Disorders; Platelet Count | 1996 |
Transformation of severe aplastic anemia into acute myeloblastic leukemia with monosomy 7.
Topics: Adult; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Transplantation; Chromosomes, Human, Pair 7; Cyclosporine; Erythropoietin; Granulocyte Colony-Stimulating Factor; Humans; Interleukin-6; Leukemia, Myeloid, Acute; Male; Monosomy | 1996 |
[Results of treatment for severe acquired aplastic anemia in children].
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Transplantation; Child; Child, Preschool; Cyclosporine; Female; Humans; Incidence; Infant; Male; Oxymetholone; Poland; Prednisolone; Severity of Illness Index; Survival Rate; Treatment Outcome | 1995 |
Sweet syndrome in a child with aplastic anemia receiving recombinant granulocyte colony-stimulating factor.
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Female; Granulocyte Colony-Stimulating Factor; Humans; Leukocyte Count; Methylprednisolone; Neutrophils; Recombinant Proteins; Skin; Sweet Syndrome | 1996 |
Fatal autoimmune pancytopenia following bone marrow transplantation for aplastic anaemia.
Topics: Adult; Anemia, Aplastic; Anemia, Hemolytic, Autoimmune; Aspergillosis; Autoantibodies; Autoimmune Diseases; Azathioprine; Bone Marrow Transplantation; Combined Modality Therapy; Cyclosporine; Disease Susceptibility; Encephalitis; Fatal Outcome; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunoglobulins, Intravenous; Immunosuppressive Agents; Lymphatic Irradiation; Male; Pancytopenia; Prednisolone; Purpura, Thrombocytopenic; Splenectomy | 1996 |
Hypercoagulability and high lipoprotein(a) levels in patients with aplastic anemia receiving cyclosporine.
Topics: Adult; Aged; Anemia, Aplastic; Blood Coagulation; Cholinesterases; Creatinine; Cyclosporine; Female; Humans; Lipoprotein(a); Male; Middle Aged; Platelet Count | 1996 |
Rejection of the second allogeneic graft in a patient with severe aplastic anemia reversed by antilymphocyte globulin and donor lymphocyte infusions.
Topics: Adult; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Transplantation; Cyclosporine; Erythropoietin; Graft Rejection; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Lymphocyte Transfusion; Male; Microsatellite Repeats; Polymerase Chain Reaction; Remission Induction; Transplantation, Homologous | 1996 |
Treatment of aplastic anemia with antithymocyte globulin, cyclosporin A, methylprednisolone, danazol and recombinant human granulocyte-colony stimulating factor.
Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Danazol; Drug Administration Schedule; Drug Therapy, Combination; Female; Granulocyte Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Male; Methylprednisolone; Recombinant Proteins | 1996 |
Methimazole-induced severe aplastic anemia: unsuccessful treatment with recombinant human granulocyte-monocyte colony-stimulating factor.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Antithyroid Agents; Blood Cell Count; Bone Marrow; Cyclosporine; Female; Glucocorticoids; Granulocyte-Macrophage Colony-Stimulating Factor; Hemoglobins; Humans; Immunosuppressive Agents; Methimazole; Middle Aged; Recombinant Proteins | 1997 |
Hepatitis-associated aplastic anemia.
Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Child; Cyclosporine; Female; Hepatitis; Hepatitis B; Humans; Immunosuppressive Agents; Leukocyte Count; Male; Recurrence; Retrospective Studies; Transaminases; Treatment Outcome | 1997 |
[Cyclosporin A in aplastic anemia in dogs: first results].
Topics: Anemia, Aplastic; Animals; Bone Marrow; Cyclosporine; Dog Diseases; Dogs; Female; Humans; Immunosuppressive Agents; Ovariectomy | 1997 |
Primary transplantation of allogeneic peripheral blood stem cell for severe aplastic anemia.
Topics: Adolescent; Anemia, Aplastic; Cyclosporine; Female; Graft vs Host Disease; Humans; Immunosuppressive Agents; Leukocytes, Mononuclear; Stem Cell Transplantation; Transplantation, Homologous | 1997 |
Comparison of long-term outcome of children with severe aplastic anemia treated with immunosuppression versus bone marrow transplantation.
Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Transplantation; Cause of Death; Child; Child, Preschool; Cohort Studies; Cyclosporine; Female; Graft vs Host Disease; Histocompatibility; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Infant; Lymphoproliferative Disorders; Male; Nuclear Family; Remission, Spontaneous; Retrospective Studies; Survival Analysis; T-Lymphocytes; Tissue Donors; Transplantation, Homologous; Treatment Outcome | 1997 |
Myelodysplastic syndrome and acute myelogenous leukemia as a late clonal complication in children with acquired aplastic anemia.
Topics: Acute Disease; Adolescent; Anemia, Aplastic; Bone Marrow Transplantation; Child; Child, Preschool; Chromosomes, Human, Pair 7; Clone Cells; Combined Modality Therapy; Cyclosporine; Drug Synergism; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Incidence; Infant; Leukemia, Myeloid; Life Tables; Male; Monosomy; Myelodysplastic Syndromes; Recombinant Proteins; Retrospective Studies; Risk Factors; Survival Analysis; Survival Rate | 1997 |
Successful bone marrow transplantation in sensitized aplastic anemia patients using total lymphoid irradiation for conditioning: long-term follow-up.
Topics: Adolescent; Adult; Anemia, Aplastic; Bone Marrow Purging; Bone Marrow Transplantation; Child; Cyclophosphamide; Cyclosporine; Drug Therapy, Combination; Female; Follow-Up Studies; Graft vs Host Disease; Humans; Immunosuppressive Agents; Lymphoid Tissue; Male; Methotrexate; Middle Aged; Risk Factors; Survival Rate; Transplantation Conditioning | 1996 |
[Myelodysplastic syndrome with monosomy 7 following combination therapy with granulocyte colony-stimulating factor, cyclosporin A and danazole in an adult patient with severe aplastic anemia].
Topics: Adult; Anemia, Aplastic; Chromosomes, Human, Pair 7; Cyclosporine; Danazol; Female; Granulocyte Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Monosomy; Myelodysplastic Syndromes | 1997 |
HLA DR2: a predictive marker in response to cyclosporine therapy in aplastic anemia.
Topics: Adolescent; Adult; Anemia, Aplastic; Child; Cyclosporine; Female; HLA-DR2 Antigen; Humans; Male; Middle Aged; Predictive Value of Tests; Retrospective Studies | 1997 |
Disappearance of cytogenetic abnormalities induced by cyclosporine therapy in a case of aplastic anemia.
Topics: Anemia, Aplastic; Chromosome Aberrations; Cyclosporine; Female; Humans; Middle Aged | 1998 |
Anti-thymocyte globulin, cyclosporin A and granulocyte colony-stimulating factor for severe aplastic anaemia complicating paediatric liver transplantation.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Child, Preschool; Cyclosporine; Female; Granulocyte Colony-Stimulating Factor; Hepatic Encephalopathy; Hepatitis, Viral, Human; Humans; Immunocompromised Host; Immunosuppressive Agents; Liver Transplantation; T-Lymphocytes | 1998 |
A case of chronic graft-versus-host-disease following allogeneic peripheral blood stem cell rescue for poor graft function after bone marrow transplantation.
Topics: Adolescent; Anemia, Aplastic; Bone Marrow Transplantation; Chronic Disease; Cyclosporine; Female; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Male; Prednisolone | 1998 |
A patient with non-A, non-B, non-C hepatitis-associated aplastic anemia recovered promptly following immuno-suppressive therapy, including antithymocyte globulin.
Topics: Adult; Anemia, Aplastic; Antilymphocyte Serum; Autoimmune Diseases; Bone Marrow Cells; Combined Modality Therapy; Cyclosporine; Erythrocyte Transfusion; Glycyrrhizic Acid; Granulocyte Colony-Stimulating Factor; Hepatitis, Viral, Human; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Lymphocyte Subsets; Male; Methylprednisolone; Oxymetholone; Platelet Transfusion | 1998 |
[Hypoplastic myelodysplastic syndrome progressing to acute myelocytic leukemia (M2) after treatment with G-CSF and immunosuppressants].
Topics: Adult; Anemia, Aplastic; Cyclosporine; Diagnosis, Differential; Female; Granulocyte Colony-Stimulating Factor; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Pancytopenia; Pregnancy; Pregnancy Complications, Hematologic; Purpura, Thrombocytopenic, Idiopathic | 1998 |
Decreased rejection and improved survival of first and second marrow transplants for severe aplastic anemia (a 26-year retrospective analysis).
Topics: Adolescent; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Child; Child, Preschool; Cyclosporine; Female; Graft Rejection; Graft vs Host Disease; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Infant; Infections; Life Tables; Male; Methotrexate; Middle Aged; Proportional Hazards Models; Retrospective Studies; Survival Analysis; Survival Rate; Transplantation, Homologous | 1998 |
[Treatment of aplastic anemia with anti-thymocyte globulin and cyclosporine].
Topics: Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Female; Humans; Immunosuppressive Agents; Lymphocyte Count; Male; Middle Aged; T-Lymphocytes; Treatment Outcome | 1998 |
Granulocyte colony-stimulating factor (G-CSF) dependent hematopoiesis with monosomy 7 in a patient with severe aplastic anemia after ATG/CsA/G-CSF combined therapy.
Topics: Adult; Anemia, Aplastic; Antilymphocyte Serum; Chromosomes, Human, Pair 7; Cyclosporine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Granulocyte Colony-Stimulating Factor; Hematopoiesis; Humans; Immunosuppressive Agents; Monosomy | 1998 |
Long-term administration of G-CSF for aplastic anaemia is closely related to the early evolution of monosomy 7 MDS in adults.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Chromosomes, Human, Pair 7; Cyclosporine; Drug Administration Schedule; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Male; Middle Aged; Monosomy; Myelodysplastic Syndromes; Retrospective Studies; Risk Factors; Survival Rate | 1998 |
Mesalazine-associated severe aplastic anemia successfully treated with antithymocyte globulin, cyclosporine and granulocyte colony-stimulating factor.
Topics: Adult; Anemia, Aplastic; Anti-Inflammatory Agents, Non-Steroidal; Antilymphocyte Serum; Cyclosporine; Drug Therapy, Combination; Granulocyte Colony-Stimulating Factor; Humans; Male; Mesalamine | 1998 |
Successful treatment with antithymocyte globulin and cyclosporin A of a severe aplastic anaemia associated with an eosinophilic fasciitis.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Eosinophilia; Fasciitis; Humans; Immunosuppressive Agents; Male; Middle Aged | 1998 |
Effectiveness of immunosuppressive therapy in older patients with aplastic anemia. European Group for Blood and Marrow Transplantation Severe Aplastic Anaemia Working Party.
Topics: Adult; Age Factors; Anemia, Aplastic; Antilymphocyte Serum; Cause of Death; Cyclosporine; Data Interpretation, Statistical; Humans; Immunosuppressive Agents; Middle Aged; Recurrence; Retrospective Studies; Risk Factors; Survival Rate; Treatment Outcome | 1999 |
Abnormal cytogenetic clones in patients with aplastic anaemia: response to immunosuppressive therapy.
Topics: Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Chromosome Aberrations; Cyclosporine; Female; Follow-Up Studies; Humans; Karyotyping; Male; Middle Aged; Oxymetholone | 1999 |
Characterization of T-cell repertoire of the bone marrow in immune-mediated aplastic anemia: evidence for the involvement of antigen-driven T-cell response in cyclosporine-dependent aplastic anemia.
Topics: Adolescent; Adult; Aged; Amino Acid Sequence; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Cells; Cloning, Molecular; Complementarity Determining Regions; Cyclosporine; DNA Primers; Female; Genes, T-Cell Receptor beta; Humans; Immunoglobulin alpha-Chains; Immunosuppressive Agents; Male; Middle Aged; Molecular Sequence Data; Polymorphism, Single-Stranded Conformational; Receptors, Antigen, T-Cell, alpha-beta; Reference Values; T-Lymphocyte Subsets | 1999 |
Improved prognosis for acquired aplastic anaemia.
Topics: Adolescent; Androgens; Anemia, Aplastic; Bone Marrow Transplantation; Child; Child, Preschool; Cohort Studies; Combined Modality Therapy; Cyclosporine; Female; Humans; Immunosuppressive Agents; Infant; Male; Prognosis; Survival Rate | 1999 |
Aplastic anemia in pregnancy: treatment with cyclosporine and granulocyte-colony stimulating factor.
Topics: Adult; Anemia, Aplastic; Blood Transfusion; Combined Modality Therapy; Cyclosporine; Female; Granulocyte Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Pregnancy; Pregnancy Complications, Hematologic | 1999 |
Aplastic anemia responsive to cyclosporine complicating the evolution of polycythemia vera.
Topics: Anemia, Aplastic; Antineoplastic Agents, Alkylating; Cyclosporine; Humans; Immunosuppressive Agents; Male; Middle Aged; Pipobroman; Polycythemia Vera | 1999 |
Cyclosporine-induced encephalopathy predisposed by diltiazem in a patient with aplastic anemia.
Topics: Aged; Anemia, Aplastic; Brain Diseases; Calcium Channel Blockers; Cyclosporine; Diltiazem; Female; Humans; Immunosuppressive Agents; Thrombocytopenia | 1999 |
High inducibility of heat shock protein 72 (hsp72) in peripheral blood mononuclear cells of aplastic anaemia patients: a reliable marker of immune-mediated aplastic anaemia responsive to cyclosporine therapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia, Aplastic; Biomarkers; Child; Cyclosporine; Female; Flow Cytometry; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Humans; Immunoblotting; Immunosuppressive Agents; Leukocytes, Mononuclear; Lymphocyte Activation; Male; Middle Aged | 1999 |
Granulocyte colony-stimulating factor-supported combined immunosuppressive therapy (antilymphocyte globulin, cyclosporine, and methylprednisolone) in patients with aplastic anemia: tolerability, efficacy, and changes in the progenitor cell compartment.
Topics: Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Drug Therapy, Combination; Drug Tolerance; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Granulocytes; Hematopoietic Stem Cells; Humans; Immunosuppressive Agents; Leukocyte Count; Male; Methylprednisolone; Middle Aged; Platelet Count; Reticulocyte Count; Therapeutic Equivalency | 1999 |
[Detection of PNH clones using flow cytometry in aplastic anemia and paroxysmal nocturnal hemoglobinuria].
Topics: Adult; Anemia, Aplastic; Antilymphocyte Serum; CD55 Antigens; CD59 Antigens; Clone Cells; Cyclosporine; Female; Flow Cytometry; Granulocytes; Hemoglobinuria; Hemoglobinuria, Paroxysmal; Hemolysis; Humans; Immunosuppressive Agents; Male; Middle Aged; T-Lymphocytes | 1999 |
[Aplastic anemia and viral hepatitis (posthepatitic aplastic anemia)].
Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Female; Hepatitis B; Hepatitis C; Hepatitis, Viral, Human; Humans; Immunosuppressive Agents; Male; Splenectomy; Time Factors | 1999 |
Continuous infusion cyclosporine and nifedipine to day +100 with short methotrexate and steroids as GVHD prophylaxis in unrelated donor transplants.
Topics: Adolescent; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Calcium Channel Blockers; Cause of Death; Child; Child, Preschool; Cyclosporine; Drug Therapy, Combination; Female; Graft vs Host Disease; Hematologic Neoplasms; Humans; Immunosuppressive Agents; Infant; Life Tables; Male; Methotrexate; Methylprednisolone; Middle Aged; Nifedipine; Survival Analysis; Transplantation, Homologous; Treatment Outcome; Wiskott-Aldrich Syndrome | 1999 |
Immune recovery after bone marrow and peripheral blood stem cells transplantation.
Topics: Adult; Anemia, Aplastic; Bone Marrow Transplantation; Cyclosporine; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunophenotyping; Immunosuppressive Agents; Leukemia; Lymphoma, Non-Hodgkin; Methotrexate; Middle Aged; Multiple Myeloma; T-Lymphocytes; Transplantation, Autologous; Transplantation, Homologous | 1999 |
Treatment results in aplastic anemia trials need to be analyzed separately for pediatric and adult populations.
Topics: Adult; Age Factors; Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Clinical Trials as Topic; Cyclosporine; Humans; Immunosuppressive Agents; Treatment Outcome | 1999 |
High-dose peripheral blood stem cell transplant for multitransfused severe aplastic anaemia patients without antithymocyte globulin in the conditioning regimen.
Topics: Acute Disease; Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Blood Transfusion; Cyclophosphamide; Cyclosporine; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Male; Methotrexate | 1999 |
Results at a single centre of immunosuppression with cyclosporine A in 66 children with aplastic anaemia.
Topics: Anemia, Aplastic; Child; Cyclosporine; Female; Humans; Immunosuppressive Agents; Male; Recurrence; Retrospective Studies; Survival Analysis; Treatment Outcome | 1999 |
Malignant neoplasms in long-term survivors of bone marrow transplantation. Late Effects Working Party of the European Cooperative Group for Blood and Marrow Transplantation and the European Late Effect Project Group.
Topics: Adolescent; Adult; Age Factors; Analysis of Variance; Anemia, Aplastic; Bone Marrow Transplantation; Child; Cyclosporine; Female; Graft vs Host Disease; Humans; Immunosuppressive Agents; Leukemia; Male; Neoplasms, Second Primary; Proportional Hazards Models; Retrospective Studies; Risk Factors; Survival Analysis; Time Factors | 1999 |
Severe aplastic anaemia--complete response to antilymphocyte globulin and cyclosporin.
Topics: Anemia, Aplastic; Anti-Inflammatory Agents; Antilymphocyte Serum; Child; Cyclosporine; Drug Therapy, Combination; Humans; Hydrocortisone; Immunosuppressive Agents; Male | 1999 |
Highly fluorescent reticulocyte count predicts haemopoietic recovery after immunosuppression for severe aplastic anaemia.
Topics: Adolescent; Adult; Anemia, Aplastic; Cyclosporine; Female; Fluorescent Dyes; Granulocyte Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Leukocyte Count; Male; Reticulocytes; Sensitivity and Specificity; T-Lymphocytes | 1999 |
Syngeneic peripheral blood stem cell transplantation with brief immunosuppression for severe aplastic anemia.
Topics: Adult; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Female; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Male; Prednisolone | 2000 |
Very severe aplastic anemia following resection of lymphocytic thymoma: effectiveness of antilymphocyte globulin, cyclosporin A, and granulocyte-colony stimulating factor.
Topics: Adult; Anemia, Aplastic; Cyclosporine; Globins; Granulocyte Colony-Stimulating Factor; Humans; Male; Postoperative Complications; T-Lymphocytes; Thymoma; Thymus Neoplasms | 2000 |
Transformation of severe aplastic anemia into myelodysplastic syndrome with monosomy 7: monoclonal origin detected by HUMARA gene analysis during the aplastic anemia phase.
Topics: Aged; Anemia, Aplastic; Chromosomes, Human, Pair 7; Clone Cells; Cyclosporine; Cytogenetic Analysis; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Humans; Monosomy; Myelodysplastic Syndromes; Receptors, Androgen | 2000 |
Second early allogeneic stem cell transplantations for graft failure in acute leukaemia, chronic myeloid leukaemia and aplastic anaemia. French Society of Bone Marrow Transplantation.
Topics: Adolescent; Adult; Anemia, Aplastic; Chi-Square Distribution; Child; Child, Preschool; Cyclosporine; Female; Follow-Up Studies; Graft Rejection; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Infant; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Proportional Hazards Models; Reoperation; Retrospective Studies; Statistics, Nonparametric; Transplantation, Homologous; Treatment Outcome | 2000 |
Long-term outcome of acquired aplastic anaemia in children: comparison between immunosuppressive therapy and bone marrow transplantation.
Topics: Adolescent; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Transplantation; Cell Count; Child; Child, Preschool; Cyclosporine; Disease-Free Survival; Female; Follow-Up Studies; Graft vs Host Disease; Humans; Immunosuppressive Agents; Infant; Male; Retrospective Studies; Statistics, Nonparametric; T-Lymphocytes | 2000 |
Cyclosporin for sulphasalazine-induced aplastic anaemia in a patient with early rheumatoid arthritis.
Topics: Aged; Anemia, Aplastic; Antirheumatic Agents; Arthritis, Rheumatoid; Cyclosporine; Female; Humans; Immunosuppressive Agents; Sulfasalazine; Treatment Outcome | 2000 |
Resolution of cyclosporine-induced gingival hyperplasia resistant to azithromycin by switching to tacrolimus.
Topics: Anemia, Aplastic; Azithromycin; Cyclosporine; Female; Gingival Hyperplasia; Humans; Middle Aged; Tacrolimus | 2001 |
[Treatment of chronic aplastic anemia with triolandren and cyclosporin A].
Topics: Adolescent; Adult; Anemia, Aplastic; Cell Division; Cells, Cultured; Child; Chronic Disease; Cyclosporine; Delayed-Action Preparations; Drug Therapy, Combination; Female; Hematopoietic Stem Cells; Humans; Immunosuppressive Agents; Male; Middle Aged; Testosterone | 1998 |
Telomere length changes in patients with aplastic anaemia.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Blotting, Southern; Case-Control Studies; Child; Child, Preschool; Cyclosporine; Hematopoietic Stem Cells; Humans; Immunosuppressive Agents; Logistic Models; Lymphocytes; Middle Aged; Statistics, Nonparametric; Telomere | 2001 |
High-dose cyclophosphamide in aplastic anaemia.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Transplantation; Cyclophosphamide; Cyclosporine; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Middle Aged | 2001 |
Toxic epidermal necrolysis in a patient with severe aplastic anemia treated with cyclosporin A and G-CSF.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anemia, Aplastic; Cyclosporine; Granulocyte Colony-Stimulating Factor; Humans; Male; Penicillin V; Penicillins; Severity of Illness Index; Stevens-Johnson Syndrome | 2001 |
Relative increase of granulocytes with a paroxysmal nocturnal haemoglobinuria phenotype in aplastic anaemia patients: the high prevalence at diagnosis.
Topics: Adult; Aged; Anemia, Aplastic; Antigens, CD; Antilymphocyte Serum; Cell Differentiation; Cyclosporine; Diagnosis, Differential; Female; Glycosylphosphatidylinositols; Granulocytes; Hemoglobinuria, Paroxysmal; Humans; Immunophenotyping; Immunosuppressive Agents; Leukocyte Count; Male; Middle Aged; T-Lymphocytes | 2001 |
T-Cell type acute lymphoblastic leukemia following cyclosporin A therapy for aplastic anemia.
Topics: Adolescent; Anemia, Aplastic; Cell Transformation, Neoplastic; Clone Cells; Cyclosporine; Gene Rearrangement; Humans; Immunophenotyping; Leukemia, T-Cell; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, Antigen, T-Cell | 2001 |
[Effectiveness of cyclosporin A in the treatment of adult patients with aplastic anemia].
Topics: Adolescent; Adult; Anemia, Aplastic; Cyclosporine; Erythropoiesis; Female; Humans; Immunosuppressive Agents; Male; Middle Aged; Recurrence; Survival Analysis; Time Factors | 2001 |
Single institution outcomes of treatment of severe aplastic anaemia.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Transplantation; Child; Cyclosporine; Female; Graft vs Host Disease; Humans; Immunosuppressive Agents; Male; Middle Aged; Retrospective Studies; Survival Analysis; Transplantation, Homologous; Treatment Outcome | 2001 |
Successful treatment with cyclosporin A for myelodysplastic syndrome with erythroid hypoplasia associated with T-cell receptor gene rearrangements.
Topics: Aged; Anemia, Aplastic; Blotting, Southern; Cyclosporine; Female; Gene Rearrangement, beta-Chain T-Cell Antigen Receptor; Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor; Gene Rearrangement, T-Lymphocyte; Humans; Immunosuppressive Agents; Male; Middle Aged; Myelodysplastic Syndromes; Polymerase Chain Reaction | 2001 |
Severe oral manifestations of chronic graft-vs.-host disease.
Topics: Adult; Anemia, Aplastic; Anti-Inflammatory Agents; Betamethasone; Bone Marrow Transplantation; Chronic Disease; Cyclosporine; Female; Glucocorticoids; Graft vs Host Disease; Humans; Immunosuppressive Agents; IMP Dehydrogenase; Methotrexate; Mouth Diseases; Mouthwashes; Mycophenolic Acid; Oral Hygiene; Prednisone; Transplantation Conditioning; Transplantation, Homologous | 2001 |
[Successful combined therapy with ATG, cyclosporin and G-CSF for both liver dysfunction and bone marrow failure in hepatitis-associated aplastic anemia].
Topics: Adult; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Drug Therapy, Combination; Granulocyte Colony-Stimulating Factor; Hepatitis; Humans; Immunosuppressive Agents; Male; Treatment Outcome | 2001 |
Cyclosporin A-induced encephalopathy after allogeneic bone marrow transplantation with prevention of graft-versus-host disease by tacrolimus.
Topics: Adult; Anemia, Aplastic; Anticonvulsants; Blood-Brain Barrier; Bone Marrow Transplantation; Brain Diseases; Brain Edema; Ceftazidime; Cerebral Hemorrhage; Cyclosporine; Diagnosis, Differential; Diuretics; Endothelium, Vascular; Epilepsy, Generalized; Female; Fluconazole; Graft vs Host Disease; Headache; Humans; Immunosuppressive Agents; Intracranial Hypertension; Magnetic Resonance Imaging; Tacrolimus; Transplantation Conditioning; Transplantation, Homologous | 2001 |
Oral manifestations in patients with aplastic anemia.
Topics: Adult; Analysis of Variance; Anemia, Aplastic; Confidence Intervals; Cyclosporine; Dental Care for Chronically Ill; DMF Index; Female; Follow-Up Studies; Gingival Hemorrhage; Gingival Hyperplasia; Humans; Immunosuppressive Agents; Logistic Models; Male; Mouth Diseases; Odds Ratio; Oral Ulcer; Periodontal Diseases; Purpura; Risk Factors; Stomatitis, Herpetic; Treatment Outcome | 2001 |
Fatal acute hepatic failure induced by danazol in a patient with endometriosis and aplastic anemia.
Topics: Anemia, Aplastic; Cyclosporine; Danazol; Endometriosis; Estrogen Antagonists; Fatal Outcome; Female; Humans; Immunosuppressive Agents; Liver Failure, Acute; Middle Aged | 2001 |
Successful non-myeloablative stem cell transplantation for a heavily transfused woman with severe aplastic anemia complicated by heart failure.
Topics: Adult; Anabolic Agents; Anemia, Aplastic; Antilymphocyte Serum; Combined Modality Therapy; Cyclosporine; Diabetes Complications; Female; Heart Failure; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Iron Overload; Methylprednisolone; T-Lymphocytes; Transfusion Reaction; Transplantation Conditioning; Transplantation, Homologous; Vidarabine | 2001 |
[Cyclosporin A and erhuang sangshenzi decoction in treating 32 cases of severe aplastic anemia].
Topics: Adolescent; Adult; Anemia, Aplastic; Child; Cyclosporine; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Humans; Immunosuppressive Agents; Male; Middle Aged | 1999 |
CsA-based post-graft immunosuppression: the main factor for improving outcome of allografted patients with acquired aplastic anemia. A retrospective survey by the Spanish Group of Hematopoietic Transplantation.
Topics: Adolescent; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Combined Modality Therapy; Cyclosporine; Female; Graft Survival; Graft vs Host Disease; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Male; Methotrexate; Prognosis; Retrospective Studies; Risk Factors; Survival Analysis; Transplantation, Isogeneic; Treatment Outcome | 2002 |
Double bone marrow transplantation for severe aplastic anemia after orthotopic liver transplantation: implications for clinical management and immune tolerance.
Topics: Adrenal Cortex Hormones; Anemia, Aplastic; Bone Marrow Transplantation; Child, Preschool; Cyclosporine; Graft Rejection; Humans; Immune Tolerance; Immunosuppressive Agents; Liver Failure; Liver Transplantation; Male; Transplantation Conditioning | 2002 |
Aplastic anemia and paroxysmal nocturnal hemoglobinuria: a follow-up study of the glycosylphosphatidylinositol-anchored proteins defect.
Topics: Adult; Anemia, Aplastic; Antilymphocyte Serum; Blood Cell Count; Bone Marrow Transplantation; Clone Cells; Combined Modality Therapy; Cyclosporine; Female; Flow Cytometry; Follow-Up Studies; Glycosylphosphatidylinositols; Hemoglobinuria, Paroxysmal; Humans; Immunosuppressive Agents; Immunotherapy; Male; Membrane Proteins; Middle Aged; Pregnancy; Pregnancy Complications, Hematologic; Prospective Studies; T-Lymphocytes; Transplantation, Homologous | 2000 |
A case of factitious aplastic anemia.
Topics: Adult; Anemia, Aplastic; Antilymphocyte Serum; Antineoplastic Agents, Alkylating; Busulfan; Cyclosporine; Factitious Disorders; Female; Granulocyte Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Pancytopenia; Self-Injurious Behavior; Treatment Refusal | 2001 |
Elevated blood drug levels obtained from indwelling silicon catheters during oral cyclosporine A administration.
Topics: Administration, Oral; Anemia, Aplastic; Catheters, Indwelling; Child; Cyclosporine; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Infusions, Intra-Arterial; Male; Monitoring, Immunologic; Silicon | 2002 |
[Combined antithymocyte globulin. cyclosporin. methylprednisolone and granulocyte colony-stimulating factor are effective in a patient with hepatitis-associated severe aplastic anemia].
Topics: Acute Disease; Adult; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Drug Therapy, Combination; Granulocyte Colony-Stimulating Factor; Hepatitis; Humans; Immunosuppressive Agents; Male; Methylprednisolone; Remission Induction; Severity of Illness Index | 2002 |
Changes in T-cell receptor VB repertoire in aplastic anemia: effects of different immunosuppressive regimens.
Topics: Adolescent; Adult; Anemia, Aplastic; Antilymphocyte Serum; Child; Complementarity Determining Regions; Cyclophosphamide; Cyclosporine; Gene Rearrangement, beta-Chain T-Cell Antigen Receptor; Humans; Immunosuppressive Agents; Lymphocyte Count; Middle Aged; Receptors, Antigen, T-Cell, alpha-beta | 2002 |
Late graft rejection following allogeneic bone marrow transplantation in aplastic anemia.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Transplantation; Child; Child, Preschool; Cyclophosphamide; Cyclosporine; Female; Graft Rejection; Histocompatibility Testing; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Male; Time Factors; Transplantation, Homologous; Whole-Body Irradiation | 2002 |
Severe aplastic anaemia and Grave's disease in a paediatric patient.
Topics: Anemia, Aplastic; Antilymphocyte Serum; Attention Deficit Disorder with Hyperactivity; Child; Cyclosporine; Drug Therapy, Combination; Graves Disease; Humans; Immunosuppressive Agents; Male; Platelet Count; Prednisone | 2002 |
[Alternative approaches to the treatment of aplastic anemia patients].
Topics: Adolescent; Adult; Anemia, Aplastic; Blood Transfusion; Chronic Disease; Combined Modality Therapy; Cyclosporine; Erythrocyte Transfusion; Female; Humans; Leukapheresis; Male; Middle Aged; Remission Induction; Splenectomy | 1992 |
[The use of cyclosporin A in treating partial red-cell aplasia of the bone marrow and aplastic anemia].
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Cyclosporine; Drug Evaluation; Female; Humans; Male; Red-Cell Aplasia, Pure | 1992 |
Expansion of a paroxysmal nocturnal hemoglobinuria (PNH) clone after cyclosporine therapy for aplastic anemia/PNH syndrome.
Topics: Adult; Anemia, Aplastic; Bone Marrow; Clone Cells; Cyclosporine; DNA; Female; Granulocytes; Hemoglobinuria, Paroxysmal; Humans; Karyotyping; Leukocytes; Syndrome | 1992 |
Ketoconazole and high-dose methylprednisolone predisposing to cyclosporine-induced seizures: report of 3 cases.
Topics: Adolescent; Adult; Anemia, Aplastic; Cyclosporine; Drug Therapy, Combination; Female; Humans; Immunosuppression Therapy; Ketoconazole; Male; Methylprednisolone; Seizures | 1992 |
[Successful treatment with combination of methylprednisolone, antilymphocyte globulin and cyclosporine in two cases of aplastic anemia].
Topics: Anemia, Aplastic; Antilymphocyte Serum; Child; Child, Preschool; Cyclosporine; Drug Therapy, Combination; Female; Humans; Immunotherapy; Male; Methylprednisolone; Remission Induction | 1992 |
Effectiveness of low dose cyclosporine in acquired aplastic anaemia with severe neutropenia.
Topics: Adult; Aged; Anemia, Aplastic; Cyclosporine; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Neutropenia; Prednisolone; Prednisone; Treatment Outcome | 1992 |
Low-dose cyclosporin for severe aplastic anemia.
Topics: Adolescent; Anemia, Aplastic; Cyclosporine; Humans | 1992 |
Interferon-gamma gene expression in unstimulated bone marrow mononuclear cells predicts a good response to cyclosporine therapy in aplastic anemia.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Base Sequence; Bone Marrow; Cyclosporine; Female; Gene Expression; Humans; Interferon-gamma; Male; Middle Aged; Molecular Sequence Data; Monocytes; Oligodeoxyribonucleotides; Oligonucleotides, Antisense; Polymerase Chain Reaction; Prognosis; RNA, Messenger | 1992 |
Hemolysis of transfused group O red blood cells in minor ABO-incompatible unrelated-donor bone marrow transplants in patients receiving cyclosporine without posttransplant methotrexate.
Topics: ABO Blood-Group System; Adult; Anemia, Aplastic; Antibodies; Blood Component Transfusion; Blood Group Incompatibility; Bone Marrow Transplantation; Coombs Test; Cyclosporine; Hemolysis; Humans; Immunosuppression Therapy; Leukemia; Methotrexate; Middle Aged; Myelodysplastic Syndromes | 1992 |
Treatment of adults with severe aplastic anemia: primary therapy with antithymocyte globulin (ATG) and rescue of ATG failures with bone marrow transplantation.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anemia, Aplastic; Antilymphocyte Serum; Blood Transfusion; Bone Marrow Transplantation; Cancer Care Facilities; Clinical Protocols; Combined Modality Therapy; Cyclosporine; Female; Follow-Up Studies; Hematopoiesis; Hemoglobins; Histocompatibility Testing; Humans; Immunosuppression Therapy; Leukocyte Count; Middle Aged; Ontario; Prognosis; Salvage Therapy; Severity of Illness Index; Survival Rate; T-Lymphocytes; Treatment Outcome | 1992 |
Cyclosporin A in aplastic anemia--report of a workshop.
Topics: Androgens; Anemia, Aplastic; Antilymphocyte Serum; Blood Platelets; Cyclosporine; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Immunosuppression Therapy; Isoantibodies; Recurrence | 1992 |
The successful treatment of two cases of severe aplastic anaemia with granulocyte-colony stimulating factor and cyclosporine A.
Topics: Anemia, Aplastic; Child; Cyclosporine; Drug Therapy, Combination; Female; Granulocyte Colony-Stimulating Factor; Humans; Male; Recombinant Proteins | 1991 |
Bone marrow transplantation for severe aplastic anemia: influence of conditioning and graft-versus-host disease prophylaxis regimens on outcome.
Topics: Adolescent; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Child; Child, Preschool; Cyclophosphamide; Cyclosporine; Female; Graft vs Host Disease; Humans; Immunosuppression Therapy; Infant; Male; Methotrexate; Whole-Body Irradiation | 1992 |
Vincristine therapy for severe platelet alloimmunization.
Topics: Anemia, Aplastic; Antibody Formation; Antilymphocyte Serum; Blood Platelets; Combined Modality Therapy; Cyclosporine; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Hemorrhagic Disorders; Humans; Immunization; Immunoglobulin G; Immunologic Factors; Infant; Isoantibodies; Macrophages; Megakaryocytes; Pancytopenia; Platelet Transfusion; Prednisone; T-Lymphocytes; Thrombocytopenia; Transfusion Reaction; Vincristine | 1991 |
Medullary histiocytosis following treatment of severe aplastic anemia with recombinant human interleukin-3 in combination with antilymphocyte globulin, cyclosporin A, and methylprednisolone.
Topics: Adult; Anemia, Aplastic; Antilymphocyte Serum; Bone Marrow Diseases; Cyclosporine; Drug Therapy, Combination; Histiocytosis; Humans; Interleukin-3; Male; Methylprednisolone; Recombinant Proteins | 1991 |
Bone marrow transplantation in 107 patients with severe aplastic anemia using cyclophosphamide and thoraco-abdominal irradiation for conditioning: long-term follow-up.
Topics: Abdomen; Adolescent; Adult; Anemia, Aplastic; Bone Marrow Transplantation; Child; Cyclophosphamide; Cyclosporine; Drug Therapy, Combination; Female; Graft Survival; Graft vs Host Disease; Humans; Immunosuppression Therapy; Male; Methotrexate; Middle Aged; Multivariate Analysis; Thorax | 1991 |
Aplastic anaemia in Christchurch Hospital 1979-89.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Androgens; Anemia, Aplastic; Bone Marrow Transplantation; Child; Child, Preschool; Cyclosporine; Female; Humans; Male; Middle Aged; Retrospective Studies; Treatment Outcome | 1991 |