cyclosporine and Alloxan Diabetes

cyclosporine has been researched along with Alloxan Diabetes in 96 studies

Research

Studies (96)

TimeframeStudies, this research(%)All Research%
pre-19902 (2.08)18.7374
1990's50 (52.08)18.2507
2000's27 (28.13)29.6817
2010's14 (14.58)24.3611
2020's3 (3.13)2.80

Authors

AuthorsStudies
Arnstein, M; Cooper, ME; Coughlan, MT; Forbes, JM; Granata, C; Henstridge, DC; Higgins, GC; Lindblom, RSJ; Nguyen, TV; Snelson, M; Thallas-Bonke, V1
Chen, F; Wang, P; Zhang, X1
Min, SN; Yu, GY; Zhu, YY1
Acebes, A; Brito-Casillas, Y; Cuesto, G; De Vries, APJ; Porrini, E; Rodriguez-Rodriguez, AE; Salido, E; Torres, A; Triñanes, J; Wagner, A1
Bondan, EF; Monteiro Martins, Mde F1
Angaswamy, N; Banan, B; Benshoff, N; Chapman, W; Mohanakumar, T; Tiriveedhi, V1
Díez-Fuentes, ML; Fumero, C; Luis Lima, S; Porrini, E; Rodríguez-Rodríguez, AE; Salido, E; Torres, A; Triñanes, J; Vega-Prieto, MJ; Velázquez-García, S1
Alimoradi, H; Asgari, M; Barzegar-Fallah, A; Dehpour, AR; Razmi, A; Shafiei, M1
Cui, J; Li, DQ; Qiu, MC; Zhang, JS; Zhang, P; Zhang, X2
Borlak, J; Niehof, M1
Amann, K; Daniel, C; Hugo, C; Stief, A; Vogelbacher, R; Wittmann, S1
Carmines, PK; Foster, JM; Pollock, JS1
Ghee, JY; Han, DH; Kim, J; Kim, SH; Li, C; Piao, SG; Song, HK; Song, JH; Yang, CW; Yoon, HE1
Gooch, JL; Knotts, TL; Molkentin, JD; Price, SR; Reddy, RN; Roberts, BR1
Alkharfy, KM1
Agardh, CD; Agardh, E; Fredrikson, GN; Gomez, MF; González Bosc, LV; Hultgårdh-Nilsson, A; Nilsson, J; Nilsson-Berglund, LM; Nilsson-Ohman, J; Salehi, A; Sigvardsson, M; Smith, ML; Wamhoff, BR; Zetterqvist, AV1
Bouwman, E; Rijkelijkhuizen, JK; Terpstra, OT; Töns, A1
Cui, SH; Li, F; Liu, S; Luo, B; Sun, HC; Sun, JB; Xin, MJ1
Ahmadiasl, N; Badalzadeh, R; Ebrahimi, H; Farajnia, S; Mohammadi, M; Najafi, M1
Bostian, PA; Brown, DA; Frasier, CR; Lust, RM; Moukdar, F; Patel, HD; Sloan, RC1
Chen, XM; Fang, YH; Lei, B; Shen, Q; Zhang, XD; Zong, YJ1
Byun, Y; Hwang, JW; Jeong, JH; Jung, MJ; Lee, DY; Moon, HT; Yook, S1
Abboud, HE; Barnes, JL; Garcia, S; Gooch, JL1
Ha, JC; Han, DJ; Jeong, YL; Kim, SC; Lee, AY; Lee, HK; Lee, SK; Wee, YM1
Biessels, GJ; Gispen, WH; Kamal, A; Ramakers, GM1
Bennet, W; Goto, M; Groth, CG; Korsgren, O; Maeda, A; Wennberg, L; Zhang, J1
Deng, S; Li, X; Wang, Y; Zhao, G1
Cetkovic-Cvrlje, M; Dragt, AL; Uckun, FM1
Corsi, M; Ferrero, ME; Gaja, G; Marni, A; Parise, M; Salari, PC1
Amaratunga, A; Khoury, P; Tuch, BE; Wang, L; Williams, L1
Christians, U; Colvin, RB; Graham, M; Hering, BJ; Ingulli, E; Kirchhof, N; Schuurman, HJ; Wijkstrom, M1
Coombes, JD; Couser, WG; Pippin, JW; Rangan, GK1
Dufour, JM; Kin, T; Kobayashi, T; Korbutt, GS; Rajotte, RV1
Antonakis, PT; Flogeras, D; Fotiadis, C; Karampela, E; Papalois, AE; Sfiniadakis, I; Xekouki, P; Zografos, G1
Najjar, TA; Saad, SY1
Ahn, KO; Choi, YH; Chung, BH; Ito, S; Kim, J; Li, C; Lim, SW; Sugawara, A; Sun, BK; Yang, CW; Yang, JH; Yoon, KH1
Byun, Y; Lee, DY; Nam, JH; Park, SJ2
Fox, M; Greaves, M; Johnson, BF; Preston, FE; Raftery, AT; Wiley, KN1
Cook, HW; Fraser, RB; Kapoor, S; Wright, JR1
Borel, JF; Lu, X1
Carotenuto, P; Leslie, RD; Pozzilli, P1
Ar'Rajab, A; Dawidson, IJ; Harris, RB; Sentementes, JT1
Cheung, SS; Tai, J; Tze, WJ2
Kearns, H; Wright, JR1
Kearns, H; McDonald, AS; Wright, JR1
Epstein, S; Jee, WS; Joffe, II; Katz, IA; Ke, HZ; Li, M; Liang, XG; Romero, DF; Stein, B; Takizawa, M1
Chou, TC; Field, JF; Gores, PF; Sutherland, DE1
Bonthuis, F; Bouwman, E; Ijzermans, JN; Kouwenhoven, E; Marquet, RL; Scheringa, M; van Rooijen, N; Wolvekamp, MC1
Gores, PF; Hower, C; Lloveras, JK; Soon-Shiong, P; Stephanian, E; Sutherland, DE; Wahoff, DC1
Kamei, J; Kasuya, Y; Kawashima, N; Misawa, M; Suzuki, T1
Andersson, A; Groth, CG; Korsgren, O; Sandberg, JO1
Barrera, J; Demetriou, AA; Lebow, LT; Morsiani, E; Rozga, J; Young, JD1
Cheung, SS; Tai, J; Tsang, A; Tze, WJ1
Andereggen, E; Bubloz, C; Bühler, L; Deng, S; Fournier, B; Morel, P1
Chick, WL; Ecker, DM; Kühtreiber, WM; Lanza, RP; Marsh, JP; Staruk, JE1
Gruessner, AC; Gruessner, RW; Matas, AJ; Moon, C; Nakhleh, RE; Papalois, BE; Troppmann, C1
Chen, H; Daloze, P; Qi, S; Xu, D1
Gruessner, AC; Gruessner, RW; Matas, AJ; Moon, C; Nakhleh, RE; Papalois, BE; Sehgal, SN; Troppmann, C1
Gupta, RC; Mathur, AK; Prasad, N; Sharma, P1
Chen, S; Li, JW; Ma, SX; Wang, Y; Yan, YH1
Kristal, BS; Matsuda, M; Yu, BP1
Cíhalová, E; Kazdová, L; Nozicková, M; Ruzbarský, V; Saudek, F; Vrána, A1
Hikichi, N; Iizuka, Y; Murata, R; Ogata, M1
Bartlett, ST; Delatorre, A; Hadley, GA; Johnson, LB; Kuo, PC; Schweitzer, EJ1
Cheung, SC; Tai, J; Tze, WJ1
Chong, AS; Foster, P; Guo, Z; Jensik, S; McChesney, L; Mital, D; Sankary, H; Shen, J; Tian, Y; Williams, JW; Yin, D1
Chong, AS; Foster, PF; Fu, Z; Guo, Z; Jensik, S; McChesney, LP; Mital, D; Sankary, HN; Shen, J; Tian, Y; Williams, JW1
Hikichi, N; Iizuka, Y; Murata, R; Ogata, M; Suzuki, S; Toyota, T; Uchimura, T1
Arita, S; Atiya, A; Kasraie, A; Mullen, Y; Ohtsuka, S; Shevlin, L; Une, S1
Cheung, S; Tai, J; Tsang, A; Tze, WJ1
du Toit, D; Louw, J; Muller, C; Page, B1
Choi, HS; Chun, YC; Ha, JH; Kang, JS; Kim, DS; Kim, JH; Lee, CH; Shin, IC1
Erley, CM; Heyne, N; Merten, S; Osswald, H; Petersen, P; Risler, T; Schöber, W; Wolf, S1
Fujimura, A; Green, M; Kamada, N; Kobayashi, E; Lord, R; Miyata, M; Toyama, N1
Davaris, P; Golematis, B; Karamanos, V; Lykoudis, E; Nikolaou, A; Nikolaou, C; Papadimitriou, L; Papalois, A; Papalois, B; Pataryas, T; Smyrniotis, V; Tountas, C1
Fujimura, A; Green, M; Kamada, N; Kobayashi, E; Lord, R; Uchida, H; Walker, NI1
Bari, S; Bennet, W; Groth, CG; Korsgren, O; Nava, S; Song, Z; Sundberg, B; Wennberg, L; Zhang, J2
Jeon, SD; Moon, CK; So, DS; Yang, KM1
Carmo, A; Carvalho, AP; Cunha-Vaz, JG; Lopes, MC1
Auchincloss , H; Boskovic, S; C Ko, DS; Colvin, RB; Cosimi, AB; Kawai, T; Koulmanda, M; O'Neil, JJ; Sachs, DH; Smith, RN; Sogawa, H; Sykes, M; Wee, SL1
Demetriou, AA; Fogli, L; Lanza, G; Lebow, LT; Morsiani, E; Rozga, J1
Breim, LC; De-Macedo, AR; Machado, JL; Mercadante, MC; Spadella, CT1
Baker, H; DeAngelis, B; Frank, O; Jyothirmayi, GN; Khalil, M; Leevy, CB; Reddi, AS1
Hisanaga, M; Nakajima, Y; Nakano, H; Segawa, M; Ueno, M; Yabuuchi, H; Yoshimura, A1
Ji-ning, L; Shao-Wen, H; Xi-yuan, Z1
Ketchum, RJ; Moore, WV; Moyer, C; Su, HC1
Dietze, O; Habringer, C; Klima, G; Königsrainer, A; Krausler, R; Margreiter, R1
Barker, CF; Berezniak, R; Dafoe, DC; Posselt, A; Tafra, L; Wang, X1
Duhault, J; Goranova, I; Jablenska, R; Marquie, G; Petkov, P; Popov, A; Vassileva, E; Zafirova, M1
Baker, H; DeAngelis, B; Frank, O; Jyothirmayi, GN; Kabaria, V; Reddi, AS1
Diamantstein, T; Dunger, A; Hahn, HJ; Kauert, C; Kuttler, B1
Atlef, N; Doll, N; Hermitte, L; Payan, MJ; Scheimann, A; Vague, P; Vialettes, B1

Reviews

1 review(s) available for cyclosporine and Alloxan Diabetes

ArticleYear
New developments in non-specific and semi-specific immunosuppression in type I diabetes.
    Diabetes/metabolism reviews, 1993, Volume: 9, Issue:4

    Topics: Animals; Antilymphocyte Serum; Cyclosporine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Insulin; Lymphokines; Photopheresis; Prediabetic State

1993

Other Studies

95 other study(ies) available for cyclosporine and Alloxan Diabetes

ArticleYear
Delineating a role for the mitochondrial permeability transition pore in diabetic kidney disease by targeting cyclophilin D.
    Clinical science (London, England : 1979), 2020, Jan-31, Volume: 134, Issue:2

    Topics: Albuminuria; Animals; Cyclosporine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Hydrogen Peroxide; Kidney; Kidney Diseases; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Peptidyl-Prolyl Isomerase F; Proton-Translocating ATPases

2020
Cyclosporine-a attenuates retinal inflammation by inhibiting HMGB-1 formation in rats with type 2 diabetes mellitus.
    BMC pharmacology & toxicology, 2020, 02-04, Volume: 21, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Cyclosporine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Retinopathy; HMGB1 Protein; Interleukin-1beta; Intravitreal Injections; Male; Rats, Sprague-Dawley; Retina; Tumor Necrosis Factor-alpha

2020
[Effect of topical injection of cyclosporine A on saliva secretion and inflammation in the submandibular gland of non-obese diabetic mice].
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2021, Aug-18, Volume: 53, Issue:4

    Topics: Animals; Cyclosporine; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Inflammation; Mice; Mice, Inbred NOD; Saliva; Sjogren's Syndrome; Submandibular Gland

2021
Deciphering Tacrolimus-Induced Toxicity in Pancreatic β Cells.
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2017, Volume: 17, Issue:11

    Topics: Animals; Calcineurin; Cyclosporine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose; Immunosuppressive Agents; Insulin; Insulin Resistance; Insulin-Secreting Cells; Nerve Tissue Proteins; NFATC Transcription Factors; Obesity; Rats; Rats, Zucker; Tacrolimus; Thinness

2017
Cyclosporine improves remyelination in diabetic rats submitted to a gliotoxic demyelinating model in the brainstem.
    Microscopy research and technique, 2013, Volume: 76, Issue:7

    Topics: Animals; Brain Stem; Cyclosporine; Demyelinating Diseases; Diabetes Mellitus, Experimental; Disease Models, Animal; Ethidium; Nerve Regeneration; Neuroprotective Agents; Rats; Rats, Wistar; Treatment Outcome

2013
Synergism of a natural plant product, oleanolic acid with calcineurin inhibitor in prolonging islet allograft survival.
    Transplant immunology, 2013, Volume: 29, Issue:1-4

    Topics: Allografts; Animals; Calcineurin; Calcineurin Inhibitors; Cyclosporine; Diabetes Mellitus, Experimental; Drug Synergism; Graft Survival; Immunosuppressive Agents; Islets of Langerhans Transplantation; Mice; Mice, Inbred BALB C; Oleanolic Acid; T-Lymphocytes

2013
Glucose homeostasis changes and pancreatic β-cell proliferation after switching to cyclosporin in tacrolimus-induced diabetes mellitus.
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2015, Volume: 35, Issue:3

    Topics: Animals; Apoptosis; Calcineurin Inhibitors; Carbohydrate Metabolism; Cell Division; Cyclosporine; Diabetes Mellitus, Experimental; Drug Substitution; Glucose; Glucose Tolerance Test; Homeostasis; Insulin Resistance; Insulin-Secreting Cells; Obesity; Proinsulin; Rats; Rats, Zucker; Tacrolimus

2015
Inhibition of calcineurin/NFAT pathway plays an essential role in renoprotective effect of tropisetron in early stage of diabetic nephropathy.
    European journal of pharmacology, 2015, Nov-15, Volume: 767

    Topics: Animals; Calcineurin; Calcineurin Inhibitors; Cyclosporine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Extracellular Matrix; Fibronectins; Hypertrophy; Indoles; Kidney Glomerulus; Male; Protective Agents; Rats; Streptozocin; Transcription Factors; Tropisetron

2015
[The effects of cyclosporine A on immunoglobulins deposition in retina of streptozotocin-induced diabetic rats].
    Zhonghua nei ke za zhi, 2008, Volume: 47, Issue:2

    Topics: Animals; Cyclosporine; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Immunoglobulins; Immunosuppressive Agents; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Retina; Streptozocin

2008
HNF4alpha and HNF1alpha dysfunction as a molecular rational for cyclosporine induced posttransplantation diabetes mellitus.
    PloS one, 2009, Volume: 4, Issue:3

    Topics: Animals; Base Sequence; Blotting, Western; Cell Line; Cyclosporine; Diabetes Mellitus, Experimental; DNA Primers; Electrophoretic Mobility Shift Assay; Hepatocyte Nuclear Factor 4; Humans; Phosphorylation; Promoter Regions, Genetic; Rats

2009
Long-term treatment of sirolimus but not cyclosporine ameliorates diabetic nephropathy in the rat.
    Transplantation, 2009, May-15, Volume: 87, Issue:9

    Topics: Animals; Cyclosporine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; DNA Primers; Fibronectins; Immunosuppressive Agents; Laminin; Male; Nephrogenic Fibrosing Dermopathy; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sirolimus; Vascular Endothelial Growth Factor A

2009
PP2B-dependent NO production in the medullary thick ascending limb during diabetes.
    American journal of physiology. Renal physiology, 2009, Volume: 297, Issue:2

    Topics: Amidines; Animals; Benzylamines; Calcineurin; Calcineurin Inhibitors; Cell Survival; Cyclic N-Oxides; Cyclosporine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme Activation; Enzyme Inhibitors; Free Radical Scavengers; Kidney Medulla; Loop of Henle; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitrites; Ornithine; Phosphorylation; Rats; Rats, Sprague-Dawley; Spin Labels; Up-Regulation

2009
Influence of sirolimus on cyclosporine-induced pancreas islet dysfunction in rats.
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2009, Volume: 9, Issue:9

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Blood Glucose; Cyclosporine; Deoxyguanosine; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glycated Hemoglobin; Immunohistochemistry; Immunosuppressive Agents; Insulin; Islets of Langerhans; Male; Rats; Rats, Sprague-Dawley; Sirolimus

2009
Calcineurin A-β is required for hypertrophy but not matrix expansion in the diabetic kidney.
    Journal of cellular and molecular medicine, 2011, Volume: 15, Issue:2

    Topics: Albumins; Animals; Blood Urea Nitrogen; Calcineurin; Cyclosporine; Diabetes Mellitus, Experimental; Extracellular Matrix; Glomerular Filtration Rate; Glucose; Hypertrophy; Insulin-Secreting Cells; JNK Mitogen-Activated Protein Kinases; Kidney; MAP Kinase Signaling System; Mice; Mice, Knockout; NFATC Transcription Factors; TOR Serine-Threonine Kinases; Transforming Growth Factor beta

2011
Influence of overt diabetes mellitus on cyclosporine pharmacokinetics in a canine model.
    Experimental diabetes research, 2009, Volume: 2009

    Topics: Alloxan; Animals; Area Under Curve; Blood Glucose; Cholesterol; Cyclosporine; Diabetes Mellitus, Experimental; Dogs; Hypoglycemia; Immunosuppressive Agents; Kinetics; Lipoproteins, LDL; Models, Statistical; Streptozocin

2009
Nuclear factor of activated T cells regulates osteopontin expression in arterial smooth muscle in response to diabetes-induced hyperglycemia.
    Arteriosclerosis, thrombosis, and vascular biology, 2010, Volume: 30, Issue:2

    Topics: Animals; Apyrase; Arteries; Binding Sites; Blood Glucose; Calcineurin; Calcineurin Inhibitors; Cyclosporine; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Disease Models, Animal; Enzyme Inhibitors; Female; Glucose Tolerance Test; Humans; Hyperglycemia; Jurkat Cells; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Muscle, Smooth, Vascular; NFATC Transcription Factors; Osteopontin; Promoter Regions, Genetic; Pyrazoles; RNA, Messenger; Signal Transduction; Time Factors; Transcriptional Activation; Transfection; Uridine Triphosphate

2010
Transplantation of long-term cultured porcine islets in the rat: prolonged graft survival and recipient growth on reduced immunosuppression.
    Cell transplantation, 2010, Volume: 19, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Cyclophosphamide; Cyclosporine; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Gadolinium; Graft Rejection; Graft Survival; Immunosuppression Therapy; Immunosuppressive Agents; Islets of Langerhans Transplantation; Male; Models, Animal; Rats; Rats, Inbred Lew; Swine; Transplantation, Heterologous

2010
Triptolide prolonged allogeneic islet graft survival in chemically induced and spontaneously diabetic mice without impairment of islet function.
    Hepatobiliary & pancreatic diseases international : HBPD INT, 2010, Volume: 9, Issue:3

    Topics: Animals; Blood Glucose; Cyclosporine; Diabetes Mellitus; Diabetes Mellitus, Experimental; Disease Models, Animal; Diterpenes; Epoxy Compounds; Female; Glucose Tolerance Test; Graft Rejection; Graft Survival; Immunosuppressive Agents; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred NOD; Phenanthrenes; Time Factors; Transplantation, Homologous; Weight Gain

2010
[The protective effects of cyclosporine A on aortic immunological injuries in STZ-induced diabetic rats].
    Zhonghua xin xue guan bing za zhi, 2010, Volume: 38, Issue:5

    Topics: Animals; Aorta; Aortic Diseases; Cyclosporine; Diabetes Mellitus, Experimental; Endothelium, Vascular; Immunosuppressive Agents; Rats; Rats, Sprague-Dawley

2010
The additive effects of ischemic postconditioning and cyclosporine-A on nitric oxide activity and functions of diabetic myocardium injured by ischemia/reperfusion.
    Journal of cardiovascular pharmacology and therapeutics, 2012, Volume: 17, Issue:2

    Topics: Animals; Cyclosporine; Diabetes Mellitus, Experimental; Enzyme-Linked Immunosorbent Assay; Ischemic Postconditioning; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Nitric Oxide; Rats; Rats, Wistar; Streptozocin

2012
Mitochondrial permeability transition in the diabetic heart: contributions of thiol redox state and mitochondrial calcium to augmented reperfusion injury.
    Journal of molecular and cellular cardiology, 2012, Volume: 52, Issue:5

    Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Signaling; Cardiotonic Agents; Cyclosporine; Diabetes Mellitus, Experimental; Glutathione; Glutathione Disulfide; Heart; Hemodynamics; In Vitro Techniques; Male; Minocycline; Mitochondria, Heart; Mitochondrial ADP, ATP Translocases; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Reperfusion Injury; Oligopeptides; Oxidation-Reduction; Permeability; Rats; Rats, Sprague-Dawley

2012
[The protective effects on the function and structure of retinae in diabetic rats by intravitreal injection of cyclosporin A].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 2012, Volume: 48, Issue:7

    Topics: Animals; Cyclosporine; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Intravitreal Injections; Male; Rats; Rats, Sprague-Dawley; Retina

2012
Synergistic effect of surface modification with poly(ethylene glycol) and immunosuppressants on repetitive pancreatic islet transplantation into antecedently sensitized rat.
    Transplantation proceedings, 2013, Volume: 45, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Biomarkers; Blood Glucose; Coculture Techniques; Cyclosporine; Diabetes Mellitus, Experimental; Drug Synergism; Drug Therapy, Combination; Immunohistochemistry; Immunosuppressive Agents; Islets of Langerhans; Islets of Langerhans Transplantation; L-Lactate Dehydrogenase; Male; Polyethylene Glycols; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Spleen; Time Factors; Tissue Culture Techniques

2013
Calcineurin is activated in diabetes and is required for glomerular hypertrophy and ECM accumulation.
    American journal of physiology. Renal physiology, 2003, Volume: 284, Issue:1

    Topics: Animals; Calcineurin; Calcineurin Inhibitors; Cyclosporine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme Inhibitors; Extracellular Matrix; Fibronectins; Gene Expression; Hypertrophy; Kidney Glomerulus; Male; Phosphoric Monoester Hydrolases; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta

2003
Tautomycetin as a novel immunosuppressant in transplantation.
    Transplantation proceedings, 2003, Volume: 35, Issue:1

    Topics: Animals; Antifungal Agents; Cyclosporine; Diabetes Mellitus, Experimental; Furans; Graft Survival; Heart Transplantation; Histocompatibility Testing; Immunosuppressive Agents; Islets of Langerhans Transplantation; Lipids; Rats; Rats, Inbred Lew; Rats, Wistar; Transplantation, Homologous

2003
Effects of a phorbol ester and cyclosporin A on hippocampal synaptic plasticity in streptozotocin-induced-diabetic rats: reduced sensitivity to phorbol esters.
    Neuroscience letters, 2003, Mar-13, Volume: 339, Issue:1

    Topics: Alkaloids; Animals; Benzophenanthridines; Calcineurin; Calcineurin Inhibitors; Cyclosporine; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Phenanthridines; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Wistar; Synaptic Transmission

2003
Immunosuppression with FTY720 and cyclosporine A inhibits rejection of adult porcine islet xenografts in rats.
    Transplantation, 2003, Apr-27, Volume: 75, Issue:8

    Topics: Animals; Blood Cell Count; Cyclosporine; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Female; Fingolimod Hydrochloride; Graft Rejection; Immunosuppression Therapy; Immunosuppressive Agents; Islets of Langerhans Transplantation; Isoantibodies; Mice; Mice, Nude; Propylene Glycols; Rats; Rats, Inbred Lew; Sphingosine; Swine; Transplantation, Heterologous

2003
[Short-term effects of cyclosporine A on the function of pancreatic islet cells in normal and spontaneous diabetic Chinese hamsters].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2003, Volume: 34, Issue:3

    Topics: Animals; Cells, Cultured; Cricetinae; Cyclosporine; Diabetes Mellitus, Experimental; Glucagon; Immunosuppressive Agents; Insulin; Insulin Secretion; Islets of Langerhans

2003
Prevention of islet allograft rejection in diabetic mice by targeting Janus Kinase 3 with 4-(4'-hydroxyphenyl)-amino-6,7-dimethoxyquinazoline (JANEX-1).
    Arzneimittel-Forschung, 2003, Volume: 53, Issue:9

    Topics: Animals; Cyclosporine; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Enzyme Inhibitors; Graft Rejection; Immunosuppressive Agents; Islets of Langerhans Transplantation; Janus Kinase 3; Major Histocompatibility Complex; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Protein-Tyrosine Kinases; Quinazolines

2003
Cyclosporine-induced insulin release in rats is related to an increase in plasma lipid levels.
    Transplant international : official journal of the European Society for Organ Transplantation, 1992, Volume: 5 Suppl 1

    Topics: Animals; Blood Glucose; Cholesterol; Cyclosporine; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glucose Intolerance; Insulin; Insulin Secretion; Male; Rats; Rats, Wistar; Streptozocin; Triglycerides

1992
Porcine pancreatic icosapeptide as a marker of graft survival and rejection in xenotransplantation.
    Xenotransplantation, 2003, Volume: 10, Issue:6

    Topics: Animals; Biomarkers; C-Peptide; Cyclosporine; Diabetes Mellitus, Experimental; Female; Graft Rejection; Graft Survival; Immunosuppressive Agents; Insulin; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Mice, SCID; Pancreas Transplantation; Pancreatic Polypeptide; Peptide Fragments; Swine; Transplantation, Heterologous

2003
Cyclosporine toxicity in immunosuppressed streptozotocin-diabetic nonhuman primates.
    Toxicology, 2005, Feb-01, Volume: 207, Issue:1

    Topics: Animals; Cyclosporine; Diabetes Mellitus, Experimental; Drug Synergism; Female; Immunocompromised Host; Immunosuppressive Agents; Islets of Langerhans Transplantation; Macaca fascicularis; Male; Renal Insufficiency; Streptozocin

2005
C5b-9 does not mediate chronic tubulointerstitial disease in the absence of proteinuria.
    Kidney international, 2005, Volume: 67, Issue:2

    Topics: Animals; Chronic Disease; Complement Membrane Attack Complex; Cyclosporine; Diabetes Mellitus, Experimental; Extracellular Matrix Proteins; Female; Immunohistochemistry; Kidney Tubules; Nephritis, Interstitial; Proteinuria; Rats; Streptozocin; Ureteral Obstruction

2005
Reversal of diabetes in pancreatectomized pigs after transplantation of neonatal porcine islets.
    Diabetes, 2005, Volume: 54, Issue:4

    Topics: Animals; Animals, Newborn; Blood Glucose; Cyclosporine; Diabetes Mellitus, Experimental; Feasibility Studies; Female; Glucose Tolerance Test; Immunosuppressive Agents; Insulin; Islets of Langerhans Transplantation; Liver; Male; Pancreatectomy; Portal Vein; Sirolimus; Swine; Time Factors

2005
Effects of mycophenolate mofetil vs cyclosporine administration on graft survival and function after islet allotransplantation in diabetic rats.
    World journal of gastroenterology, 2005, May-14, Volume: 11, Issue:18

    Topics: Animals; Cyclosporine; Diabetes Mellitus, Experimental; Graft Survival; Immunosuppressive Agents; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Mycophenolic Acid; Rats; Rats, Wistar

2005
Effects of STZ-induced diabetes and its treatment with vanadyl sulphate on cyclosporine A-induced nephrotoxicity in rats.
    Archives of toxicology, 2005, Volume: 79, Issue:9

    Topics: Animals; Cyclosporine; Diabetes Mellitus, Experimental; Glutathione; Hypoglycemic Agents; Immunosuppressive Agents; Kidney; Kidney Diseases; Kidney Function Tests; Male; Malondialdehyde; Organ Size; Rats; Rats, Wistar; Vanadium Compounds

2005
Rosiglitazone protects against cyclosporine-induced pancreatic and renal injury in rats.
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2005, Volume: 5, Issue:8

    Topics: Angiotensin II; Animals; Apoptosis; Cyclosporine; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Hypoglycemic Agents; Immunosuppressive Agents; Insulin; Islets of Langerhans; Kidney; Osteopontin; Pancreatic Diseases; Rats; Rats, Sprague-Dawley; Rosiglitazone; Sialoglycoproteins; Thiazolidinediones; Transforming Growth Factor beta; Transforming Growth Factor beta1

2005
A combination therapy of PEGylation and immunosuppressive agent for successful islet transplantation.
    Journal of controlled release : official journal of the Controlled Release Society, 2006, Jan-10, Volume: 110, Issue:2

    Topics: Animals; Blood Glucose; Cyclosporine; Diabetes Mellitus, Experimental; Excipients; Glucose Tolerance Test; Immunosuppressive Agents; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Nephrectomy; Polyethylene Glycols; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Surface Properties

2006
A new strategy toward improving immunoprotection in cell therapy for diabetes mellitus: long-functioning PEGylated islets in vivo.
    Tissue engineering, 2006, Volume: 12, Issue:3

    Topics: Animals; Cyclosporine; Diabetes Mellitus, Experimental; Immunosuppressive Agents; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Polyethylene Glycols; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Tissue Engineering

2006
Urinary thromboxane and 6-keto-prostaglandin F1 alpha are early markers of acute rejection in experimental pancreas transplantation.
    Transplantation, 1994, Jul-15, Volume: 58, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Amylases; Animals; Biomarkers; Blood Glucose; Cyclosporine; Diabetes Mellitus, Experimental; Graft Rejection; Pancreas Transplantation; Radioimmunoassay; Rats; Thromboxane B2; Transplantation, Homologous; Transplantation, Isogeneic

1994
Essential fatty acid deficiency prevents multiple low-dose streptozotocin-induced diabetes in naive and cyclosporin-treated low-responder murine strains.
    Acta diabetologica, 1995, Volume: 32, Issue:2

    Topics: Animals; Blood Glucose; Cyclosporine; Diabetes Mellitus, Experimental; Disease Susceptibility; Fatty Acids, Essential; Islets of Langerhans; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Species Specificity; Streptozocin; Time Factors

1995
Prolongation of islet xenograft survival with combined treatment of 15-deoxyspergualin or cyclosporine and anti-CD4 monoclonal antibody.
    Transplantation proceedings, 1995, Volume: 27, Issue:1

    Topics: Animals; Antibodies, Monoclonal; CD4 Antigens; Cells, Cultured; Combined Modality Therapy; Cricetinae; Cyclosporine; Diabetes Mellitus, Experimental; Graft Survival; Guanidines; Immunosuppressive Agents; Islets of Langerhans; Islets of Langerhans Transplantation; Mesocricetus; Mice; Mice, Inbred CBA; Transplantation, Heterologous

1995
Immune privilege of the testis for islet xenotransplantation (rat to mouse).
    Transplantation proceedings, 1994, Volume: 26, Issue:6

    Topics: Animals; Blood Glucose; Cells, Cultured; Cryptorchidism; Cyclosporine; Diabetes Mellitus, Experimental; Injections, Intraperitoneal; Islets of Langerhans; Islets of Langerhans Transplantation; Kidney; Male; Mice; Rats; Rats, Inbred WF; Testis; Transplantation, Heterologous

1994
In vivo studies of UV-B-irradiated adult pig islets in diabetic mice.
    Transplantation proceedings, 1994, Volume: 26, Issue:6

    Topics: Animals; Cyclosporine; Diabetes Mellitus, Experimental; Glucagon; Graft Survival; Insulin; Insulin Secretion; Islets of Langerhans Transplantation; Mice; Mice, Inbred Strains; Swine; Time Factors; Transplantation, Heterologous; Ultraviolet Rays

1994
Immunomodulation and fish-to-mouse islet xenograft survival.
    Transplantation proceedings, 1994, Volume: 26, Issue:6

    Topics: Animals; Blood Glucose; Cells, Cultured; Cyclosporine; Diabetes Mellitus, Experimental; Graft Survival; Islets of Langerhans; Islets of Langerhans Transplantation; Mice; Mice, Inbred BALB C; Mice, Nude; Tilapia; Transplantation, Heterologous

1994
Leflunomide and cyclosporin-A prolong fish-to-mouse islet xenograft survival in BALB/C mice.
    Transplantation proceedings, 1994, Volume: 26, Issue:3

    Topics: Animals; Blood Glucose; Cyclosporine; Diabetes Mellitus, Experimental; Graft Survival; Immunosuppressive Agents; Islets of Langerhans Transplantation; Isoxazoles; Leflunomide; Male; Mice; Mice, Inbred BALB C; Tilapia; Transplantation, Heterologous

1994
Effect of cyclosporin A on bone mineral metabolism in experimental diabetes mellitus in the rat.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1994, Volume: 9, Issue:4

    Topics: Animals; Blood Glucose; Bone and Bones; Bone Density; Bone Diseases, Metabolic; Bone Resorption; Calcitriol; Calcium; Cyclosporine; Diabetes Mellitus, Experimental; Male; Minerals; Osteocalcin; Osteogenesis; Parathyroid Hormone; Rats; Rats, Sprague-Dawley

1994
Synergistic interaction of 15-deoxyspergualin and cyclosporine to prolong the survival of rat islet allografts.
    Transplantation proceedings, 1994, Volume: 26, Issue:2

    Topics: Animals; Cyclosporine; Diabetes Mellitus, Experimental; Drug Synergism; Graft Survival; Guanidines; Immunosuppressive Agents; Islets of Langerhans Transplantation; Rats; Rats, Inbred Lew; Rats, Inbred WF; Regression Analysis; Transplantation, Homologous

1994
Local immunologic factors determine the occurrence of primary nonfunction of islet xenografts.
    Transplantation proceedings, 1994, Volume: 26, Issue:2

    Topics: Animals; Blood Glucose; Clodronic Acid; Cricetinae; Cyclosporine; Diabetes Mellitus, Experimental; Gamma Rays; Graft Survival; Immunosuppression Therapy; Islets of Langerhans Transplantation; Macrophages; Mesocricetus; Rats; Rats, Inbred Lew; Transplantation, Heterologous; Whole-Body Irradiation

1994
Intraperitoneal transplantation of microencapsulated canine islet allografts with short-term, low-dose cyclosporine for treatment of pancreatectomy-induced diabetes in dogs.
    Transplantation proceedings, 1994, Volume: 26, Issue:2

    Topics: Animals; Azathioprine; Blood Glucose; Capsules; Cyclosporine; Diabetes Mellitus, Experimental; Dogs; Glucose Tolerance Test; Graft Survival; Islets of Langerhans Transplantation; Pancreatectomy; Peritoneal Cavity; Transplantation, Heterotopic; Transplantation, Homologous

1994
The effects of cyclosporine on morphine-induced antinociception in diabetic mice.
    Neuroscience letters, 1993, Aug-20, Volume: 158, Issue:2

    Topics: Analgesics; Animals; Cyclosporine; Diabetes Mellitus, Experimental; Male; Mice; Mice, Inbred ICR; Morphine; Pain Measurement; Pain Threshold; Spleen

1993
15-Deoxyspergualin prolongs pancreatic islet allo- and xenograft survival in mice.
    Pharmacology & toxicology, 1993, Volume: 73, Issue:1

    Topics: Animals; Cyclosporine; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Graft Rejection; Graft Survival; Guanidines; Immunosuppressive Agents; Islets of Langerhans Transplantation; Mice; Mice, Inbred C57BL; Transplantation, Heterologous; Transplantation, Homologous

1993
Repeated intrahepatic islet allografts restore normoglycemia in cyclosporine-immunosuppressed diabetic pigs.
    Transplantation proceedings, 1995, Volume: 27, Issue:6

    Topics: Animals; Blood Glucose; Cyclosporine; Diabetes Mellitus, Experimental; Female; Immunosuppressive Agents; Islets of Langerhans Transplantation; Liver; Reoperation; Swine; Swine, Miniature; Tissue Donors; Transplantation, Heterotopic; Transplantation, Homologous

1995
In vivo function of pig islet xenografts in immunosuppressed diabetic mice.
    Transplantation proceedings, 1995, Volume: 27, Issue:6

    Topics: Animals; Antilymphocyte Serum; Cyclosporine; Diabetes Mellitus, Experimental; Graft Survival; Immunosuppression Therapy; Immunosuppressive Agents; Islets of Langerhans Transplantation; Mice; Swine; Tacrolimus; Transplantation, Heterologous

1995
Immunohistological study of islet xenograft rejection in immunosuppressed recipients.
    Transplantation proceedings, 1996, Volume: 28, Issue:2

    Topics: Animals; CD3 Complex; CD4 Antigens; CD8 Antigens; Cyclosporine; Diabetes Mellitus, Experimental; Graft Rejection; Graft Survival; Guanidines; Immunoglobulins; Immunohistochemistry; Immunosuppressive Agents; Islets of Langerhans Transplantation; Macrophage-1 Antigen; Mice; Mice, Inbred C57BL; Rats; Rats, Sprague-Dawley; Receptors, Interleukin-2; Tacrolimus; Transplantation, Heterologous

1996
A simple method for xenotransplanting cells and tissues into rats using uncoated alginate microreactors.
    Transplantation proceedings, 1996, Volume: 28, Issue:2

    Topics: Alginates; Animals; Antibodies, Heterophile; Biocompatible Materials; Blood Glucose; Cattle; Cyclosporine; Diabetes Mellitus, Experimental; Glucuronic Acid; Hexuronic Acids; Islets of Langerhans Transplantation; Microspheres; Rats; Rats, Inbred Lew; Species Specificity; Swine; Transplantation, Heterologous

1996
Impact of antipassenger lymphocyte globulin on functional graft survival of discordant xenoislet grafts from a large animal donor.
    Transplantation proceedings, 1996, Volume: 28, Issue:2

    Topics: Animals; Antilymphocyte Serum; Cyclosporine; Diabetes Mellitus, Experimental; Dogs; Graft Survival; Immunosuppressive Agents; Islets of Langerhans Transplantation; Polyenes; Rabbits; Rats; Rats, Inbred Lew; Sirolimus; Time Factors; Transplantation, Heterologous

1996
Prolongation of pancreas allograft survival by mycophenolate mofetil in the rat.
    Transplantation proceedings, 1996, Volume: 28, Issue:2

    Topics: Animals; Cyclosporine; Diabetes Mellitus, Experimental; Graft Rejection; Graft Survival; Immunosuppressive Agents; Male; Mycophenolic Acid; Pancreas Transplantation; Rats; Rats, Inbred BN; Rats, Inbred Lew; Transplantation, Homologous

1996
Perioperative immunosuppression as a critical determinant of early outcome after discordant xenoislet transplantation: a comparative study.
    Transplantation proceedings, 1996, Volume: 28, Issue:2

    Topics: Animals; Blood Glucose; Cyclosporine; Diabetes Mellitus, Experimental; Dogs; Drug Administration Schedule; Drug Therapy, Combination; Graft Survival; Guanidines; Immunosuppression Therapy; Immunosuppressive Agents; Islets of Langerhans Transplantation; Polyenes; Rats; Rats, Inbred Lew; Sirolimus; Tacrolimus; Transplantation, Heterologous

1996
Pancreatic xenotransplantation in rabbits.
    Transplantation proceedings, 1996, Volume: 28, Issue:3

    Topics: Animals; Azathioprine; Cyclosporine; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Goats; Graft Survival; Immunosuppressive Agents; Pancreas Transplantation; Prednisolone; Rabbits; Transplantation, Heterologous

1996
Effect of new thromboxane A2 synthesis inhibitor tetramethyl-pyrazine on pancreatic transplantation in diabetic rats.
    Transplantation proceedings, 1996, Volume: 28, Issue:3

    Topics: Albuminuria; Animals; Benzofurans; beta 2-Microglobulin; Cyclosporine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme Inhibitors; Immunosuppressive Agents; Kidney; Organ Size; Pancreas Transplantation; Pyrazines; Rats; Rats, Wistar; Thromboxane A2; Thromboxane-A Synthase; Transplantation, Isogeneic

1996
Abnormalities in the mitochondrial permeability transition in diabetic rats.
    Biochemical and biophysical research communications, 1996, May-15, Volume: 222, Issue:2

    Topics: Animals; Blood Glucose; Calcium; Calcium Phosphates; Cyclosporine; Diabetes Mellitus, Experimental; Kinetics; Mitochondria, Liver; Permeability; Peroxides; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Rotenone; tert-Butylhydroperoxide

1996
The effect of combination therapy with cyclosporine A and hydrocortisone on glucose metabolism in diabetic rats following pancreatic islet transplantation.
    Physiological research, 1995, Volume: 44, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Blood Glucose; Carbon Radioisotopes; Creatinine; Cyclosporine; Diabetes Mellitus, Experimental; Disease Models, Animal; Drug Therapy, Combination; Fasting; Glucose; Glucose Tolerance Test; Hydrocortisone; Immunosuppressive Agents; Insulin; Insulin Secretion; Islets of Langerhans Transplantation; Kidney; Lipid Metabolism; Liver; Portal Vein; Rats; Rats, Wistar

1995
Effect of streptozotocin-induced diabetes on cyclosporin A disposition in rats.
    Biological & pharmaceutical bulletin, 1996, Volume: 19, Issue:12

    Topics: Administration, Oral; Animals; Blood Glucose; Body Weight; Chromatography, High Pressure Liquid; Cyclosporine; Diabetes Mellitus, Experimental; Gastric Emptying; Gastrointestinal Transit; Immunosuppressive Agents; Injections, Intravenous; Intestinal Absorption; Lymphatic System; Male; Rats; Rats, Wistar

1996
Prevention of autoimmune islet allograft destruction by engraftment of donor T cells.
    Transplantation, 1997, Jan-27, Volume: 63, Issue:2

    Topics: Animals; Cyclosporine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Flow Cytometry; Graft Rejection; Graft Survival; Immunosuppressive Agents; Islets of Langerhans Transplantation; Lymph Nodes; Lymphocyte Transfusion; Male; Rats; Rats, Inbred BB; Rats, Inbred BN; Rats, Inbred WF; T-Lymphocyte Subsets; T-Lymphocytes; Time Factors; Transplantation, Homologous

1997
Effect of molecular weight exclusion of polysulfone fibers on macroencapsulated pig islet xenograft function in diabetic mice.
    Transplantation proceedings, 1997, Volume: 29, Issue:4

    Topics: Animals; Biocompatible Materials; Blood Glucose; C-Peptide; Cyclosporine; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Immunosuppressive Agents; Insulin; Islets of Langerhans Transplantation; Membranes, Artificial; Mice; Polymers; Subrenal Capsule Assay; Sulfones; Swine; Time Factors; Transplantation, Heterologous

1997
Effect of leflunomide and cyclosporine on concordant xenogeneic islet transplantation in streptozotocin-induced and autoimmune diabetic mice.
    Transplantation proceedings, 1997, Volume: 29, Issue:4

    Topics: Animals; Cyclosporine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Graft Survival; Immunosuppressive Agents; Islets of Langerhans Transplantation; Isoxazoles; Leflunomide; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Rats; Rats, Sprague-Dawley; Species Specificity; Transplantation, Heterologous

1997
Successful xenotransplantation of adult porcine islets in NOD and BALB/c mice with leflunomide and cyclosporine.
    Transplantation proceedings, 1997, Volume: 29, Issue:4

    Topics: Animals; Cyclosporine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Graft Survival; Immunosuppressive Agents; Isoxazoles; Leflunomide; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Swine; Transplantation, Heterologous

1997
Effect of non-insulin dependent diabetes on cyclosporin A disposition in Goto-Kakizaki (GK) rats.
    Biological & pharmaceutical bulletin, 1997, Volume: 20, Issue:9

    Topics: Administration, Oral; Animals; Biological Availability; Cyclosporine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Gastric Emptying; Gastrointestinal Transit; Immunosuppressive Agents; Injections, Intravenous; Lymphatic System; Rats; Rats, Inbred Strains; Rats, Wistar

1997
Pravastatin and low-dose cyclosporine treatment prevent islet allograft rejection in mice.
    Transplantation proceedings, 1998, Volume: 30, Issue:2

    Topics: Animals; Cyclosporine; Diabetes Mellitus, Experimental; Graft Rejection; Graft Survival; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunosuppressive Agents; Islets of Langerhans Transplantation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Pravastatin; Transplantation, Homologous

1998
Xenotransplantation of adult porcine islets in diabetic mice. A study of UVB irradiation, cryopreservation and immunosuppression on graft survival time.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1998, Volume: 30, Issue:8

    Topics: Animals; Blood Glucose; Cryopreservation; Cyclosporine; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Graft Survival; Immunosuppressive Agents; Islets of Langerhans Transplantation; Kinetics; Mice; Swine; Transplantation, Heterologous; Ultraviolet Rays

1998
Foetal rat pancreatic transplantation: posttransplantation development of foetal pancreatic iso- and allografts and suppression of rejection with mycophenolate mofetil (MMF) and cyclosporine based immunesuppression.
    Microscopy research and technique, 1998, Nov-15, Volume: 43, Issue:4

    Topics: Animals; Cyclosporine; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Fetal Tissue Transplantation; Graft Rejection; Immunohistochemistry; Immunosuppressive Agents; Islets of Langerhans; Mycophenolic Acid; Pancreas; Pancreas Transplantation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Transplantation, Homologous; Transplantation, Isogeneic

1998
Effect of cyclosporine on glucose tolerance in streptozotocin-diabetic rats: cyclosporine may deteriorate insulin sensitivity.
    Transplantation proceedings, 1999, Volume: 31, Issue:5

    Topics: Animals; Cyclosporine; Diabetes Mellitus, Experimental; Glucose; Glucose Tolerance Test; Insulin; Insulin Resistance; Male; Rats; Rats, Sprague-Dawley; Streptozocin

1999
Adenosine receptor antagonism in the prevention of acute cyclosporine A-nephrotoxicity in normal, diabetic and hypertensive rats.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1999, Volume: 14 Suppl 4

    Topics: Animals; Cyclosporine; Diabetes Mellitus, Experimental; Hypertension; Immunosuppressive Agents; Kidney; Purinergic P1 Receptor Antagonists; Rats; Streptozocin

1999
The fate of donor splenic lymphocytes in a long-surviving host after combined pancrea/spleen transplantation in the rat.
    Transplantation proceedings, 1999, Volume: 31, Issue:6

    Topics: Animals; Cyclosporine; Diabetes Mellitus, Experimental; Flow Cytometry; Graft Survival; Immunosuppressive Agents; Lymphocyte Transfusion; Pancreas Transplantation; Rats; Rats, Inbred Strains; Spleen; Transplantation, Homologous

1999
The role of triple immunosuppressive treatment in the successful implantation of islet grafts.
    Transplantation proceedings, 1999, Volume: 31, Issue:7

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Azathioprine; Blood Glucose; Cyclosporine; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Glucose Tolerance Test; Immunosuppressive Agents; Islets of Langerhans Transplantation; Prednisolone; Swine; Transplantation, Homologous

1999
Detection of membrane-bound and soluble-form MHC class I antigen from rat pancreas/spleen grafts during ongoing rejection.
    Transplantation proceedings, 1999, Volume: 31, Issue:8

    Topics: Animals; Cell Membrane; Cyclosporine; Diabetes Mellitus, Experimental; Graft Rejection; Graft Survival; Histocompatibility Antigens Class I; Immunosuppressive Agents; Liver; Lymphocytes; Pancreas Transplantation; Rats; Rats, Inbred Lew; Rats, Inbred Strains; Sirolimus; Spleen; Transplantation, Homologous

1999
Diabetic rats transplanted with adult porcine islets and immunosuppressed with cyclosporine, mycophenolate mofetil, and leflunomide remain normoglycemic for up to 100 days.
    Transplantation proceedings, 2000, Volume: 32, Issue:5

    Topics: Animals; Blood Glucose; Cyclosporine; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Immunosuppressive Agents; Islets of Langerhans Transplantation; Isoxazoles; Leflunomide; Mycophenolic Acid; Rats; Rats, Inbred Lew; Swine; Transplantation, Heterologous

2000
Brazilin augments cellular immunity in multiple low dose streptozotocin (MLD-STZ) induced type I diabetic mice.
    Archives of pharmacal research, 2000, Volume: 23, Issue:6

    Topics: Adjuvants, Immunologic; Animals; Benzopyrans; Cell Division; Concanavalin A; Cyclosporine; Diabetes Mellitus, Experimental; Hypersensitivity, Delayed; Hypoglycemic Agents; Immunity, Cellular; Interleukin-2; Lymphocyte Culture Test, Mixed; Male; Mice; Mice, Inbred C57BL; Receptors, Interleukin-2; Spleen; T-Lymphocytes, Regulatory

2000
Effect of cyclosporin-A on the blood--retinal barrier permeability in streptozotocin-induced diabetes.
    Mediators of inflammation, 2000, Volume: 9, Issue:5

    Topics: Animals; Blood-Retinal Barrier; Cyclooxygenase 2; Cyclosporine; Diabetes Mellitus, Experimental; Immunosuppressive Agents; Interleukin-1; Isoenzymes; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Permeability; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Streptozocin

2000
Diabetic rats transplanted with adult porcine islets and immunosuppressed with cyclosporine A, mycophenolate mofetil, and leflunomide remain normoglycemic for up to 100 days.
    Transplantation, 2001, Apr-27, Volume: 71, Issue:8

    Topics: Animals; Antibodies, Heterophile; Blood Glucose; C-Peptide; Cell Culture Techniques; Cell Separation; Cyclosporine; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Female; Graft Survival; Immunoglobulin G; Immunoglobulin M; Immunosuppressive Agents; Islets of Langerhans; Islets of Langerhans Transplantation; Isoxazoles; Leflunomide; Macrophages; Mice; Mice, Nude; Mycophenolic Acid; Rats; Rats, Inbred Lew; Swine; Transplantation, Heterologous

2001
Long-term islet allograft function in the absence of chronic immunosuppression: a case report of a nonhuman primate previously made tolerant to a renal allograft from the same donor.
    Transplantation, 2001, Jul-27, Volume: 72, Issue:2

    Topics: ABO Blood-Group System; Animals; Antilymphocyte Serum; Blood Glucose; Bone Marrow Transplantation; C-Peptide; Cell Separation; Cyclosporine; Diabetes Mellitus, Experimental; Graft Survival; Histocompatibility Testing; Immunosuppression Therapy; Insulin; Islets of Langerhans; Macaca fascicularis; Major Histocompatibility Complex; Male; Splenectomy; Transplantation, Homologous; Whole-Body Irradiation

2001
Long-term insulin independence following repeated islet transplantation in totally pancreatectomized diabetic pigs.
    Cell transplantation, 2002, Volume: 11, Issue:1

    Topics: Animals; Blood Glucose; Cells, Cultured; Cyclosporine; Diabetes Mellitus, Experimental; Feasibility Studies; Female; Glucose Tolerance Test; Immunosuppressive Agents; Injections, Intravenous; Insulin; Islets of Langerhans; Islets of Langerhans Transplantation; Pancreatectomy; Portal Vein; Swine, Miniature; Time Factors; Transplantation, Isogeneic

2002
Effects of cyclosporin A immunosuppression on pancreaticoduodenal transplantation in alloxan-diabetic rats.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1992, Volume: 25, Issue:12

    Topics: Animals; Cyclosporine; Diabetes Mellitus, Experimental; Drug Evaluation; Duodenum; Female; Immunohistochemistry; Immunosuppression Therapy; Islets of Langerhans Transplantation; Male; Pancreas; Random Allocation; Rats; Rats, Wistar; Time Factors

1992
Effect of cyclosporine treatment on carnitine and myo-inositol in diabetic rats.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1992, Volume: 101, Issue:1

    Topics: Animals; Blood Glucose; Body Weight; Carnitine; Cyclosporine; Diabetes Mellitus, Experimental; Eating; Inositol; Male; Rats; Rats, Inbred Strains

1992
Immunosuppressive effect in combination therapy of cyclosporine A, FK 506, and 15-deoxyspergualin on pancreatic islet xenotransplantation.
    Transplantation proceedings, 1992, Volume: 24, Issue:2

    Topics: Animals; Cricetinae; Cyclosporine; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Graft Rejection; Graft Survival; Guanidines; Immunosuppression Therapy; Immunosuppressive Agents; Islets of Langerhans Transplantation; Male; Mesocricetus; Rats; Rats, Inbred Strains; T-Lymphocytes; Tacrolimus; Thymus Gland; Transplantation, Heterologous

1992
Scale production of porcine isletlike cell clusters and xenotransplantation.
    Transplantation proceedings, 1992, Volume: 24, Issue:5

    Topics: Animals; Cells, Cultured; Culture Techniques; Cyclosporine; Diabetes Mellitus, Experimental; Glucose; Insulin; Insulin Secretion; Islets of Langerhans; Islets of Langerhans Transplantation; Male; Rats; Rats, Wistar; Swine; Transplantation, Heterologous

1992
Transplantation of discordant pig islet xenografts in diabetic rats.
    Diabetes research and clinical practice, 1992, Volume: 15, Issue:3

    Topics: Agglutination; Animals; Antibody Formation; Antilymphocyte Serum; Blood Glucose; Cyclosporine; Diabetes Mellitus, Experimental; Graft Survival; Hemagglutination; Insulin; Insulin Secretion; Islets of Langerhans Transplantation; Male; Rats; Rats, Inbred ACI; Swine; Time Factors; Transplantation, Heterologous

1992
Cyclosporine therapy concomitant with renal allotransplantation induces tolerance to subsequent donor MHC-identical islet grafts.
    Transplantation proceedings, 1992, Volume: 24, Issue:3

    Topics: Animals; Animals, Newborn; Cyclosporine; Diabetes Mellitus, Experimental; Immune Tolerance; Islets of Langerhans Transplantation; Kidney Transplantation; Major Histocompatibility Complex; Male; Rats; Rats, Inbred F344; Rats, Inbred WF; Transplantation, Homologous

1992
Histologic classification of pancreatic allograft rejection in the rat.
    Transplantation proceedings, 1992, Volume: 24, Issue:3

    Topics: Animals; Arteries; Cyclosporine; Diabetes Mellitus, Experimental; Endothelium, Vascular; Graft Rejection; Graft vs Host Disease; Immunosuppression Therapy; Inflammation; Pancreas Transplantation; Rats; Rats, Inbred BN; Rats, Inbred Lew; Time Factors

1992
Intraportal FK 506 improves intrahepatic islet allograft survival.
    Transplantation proceedings, 1991, Volume: 23, Issue:6

    Topics: Animals; Body Weight; Budesonide; Cyclosporine; Diabetes Mellitus, Experimental; Glucocorticoids; Graft Survival; Injections, Intravenous; Islets of Langerhans Transplantation; Portal Vein; Pregnenediones; Rats; Rats, Inbred Lew; Rats, Inbred WF; Tacrolimus; Transplantation, Homologous

1991
Morphological characteristics of the endocrine pancreas in alloxan diabetes after cyclosporin A administration.
    Cellular and molecular biology, 1991, Volume: 37, Issue:6

    Topics: Animals; Antigen-Presenting Cells; Cyclosporine; Diabetes Mellitus, Experimental; Immunohistochemistry; Islets of Langerhans; Lymphocytes; Male; Rats; Rats, Inbred Strains

1991
Vitamin and micronutrient concentrations in cyclosporine-induced renal tumor from diabetic rats.
    Life sciences, 1991, Volume: 49, Issue:21

    Topics: Adenocarcinoma; Animals; Biopterins; Blood Glucose; Carnitine; Cyclosporine; Diabetes Mellitus, Experimental; Inositol; Kidney; Kidney Neoplasms; Male; Rats; Rats, Inbred Strains; Vitamins

1991
Interleukin 2 receptor targeted immunotherapy in the prevention of autoimmune beta-cell destruction as observed in diabetic BB/OK rats grafted with BB/OK rat islets.
    Autoimmunity, 1989, Volume: 5, Issue:1-2

    Topics: Animals; Antibodies, Monoclonal; Autoimmune Diseases; Combined Modality Therapy; Cyclosporine; Diabetes Mellitus, Experimental; Graft Survival; Immunity, Cellular; Immunotherapy; Islets of Langerhans; Islets of Langerhans Transplantation; Rats; Rats, Inbred BB; Receptors, Interleukin-2

1989
High dose nicotinamide fails to prevent diabetes in BB rats.
    Autoimmunity, 1989, Volume: 5, Issue:1-2

    Topics: Age Factors; Animals; Autoimmune Diseases; Blood Glucose; Cyclosporine; Deferoxamine; Diabetes Mellitus, Experimental; DNA Damage; Drug Evaluation, Preclinical; Hyperplasia; Insulin; Insulin Secretion; Islets of Langerhans; Models, Biological; NAD; Niacinamide; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Rats, Inbred BB

1989