cyclosporine and Acute Confusional Senile Dementia

cyclosporine has been researched along with Acute Confusional Senile Dementia in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (7.41)18.2507
2000's9 (33.33)29.6817
2010's11 (40.74)24.3611
2020's5 (18.52)2.80

Authors

AuthorsStudies
Ballatore, C; Brunden, KR; Cornec, AS; Gay, B; Hoye, AT; Hyde, E; James, MJ; Lee, VM; Lou, K; Smith, AB; Trojanowski, JQ; Yao, Y1
Cho, S; Cho, SJ; Jung, SY; Kim, T; Lee, J; Min, SJ; Mook-Jung, I; Pae, AN; Park, BG; Park, JH; Park, KD; Song, H; Tae, J; Yang, H; Yang, HY1
Elkamhawy, A; Hassan, AHE; Lee, J; Moon, B; Pae, AN; Park, BG; Park, HM; Park, JE; Ra, H; Roh, EJ1
Cho, SJ; Jeong, KS; Jung, SY; Kim, T; Lee, J; Lim, SM; Londhe, AM; Morshed, MN; Pae, AN; Park, JH; Park, KD; Park, WK; Son, WS1
Elkamhawy, A; Hassan, AHE; Lee, J; Pae, AN; Park, BG; Park, JE; Roh, EJ1
Elkamhawy, A; Hassan, AHE; Lee, J; Pae, AN; Paik, S; Park, BG; Park, JE; Roh, EJ1
Brown, CA; Creton, R; Del Rosario Hernández, T; Gore, SV; Ibrahim, R; Kakodkar, R; Kreiling, JA; Tucker Edmister, S1
Olesen, MA; Quintanilla, RA; Tapia-Monsalves, C; Villavicencio-Tejo, F1
Dai, Z; Herz, J; Huuskonen, MT; Kisler, K; Körbelin, J; Ma, Q; Montagne, A; Nikolakopoulou, AM; Rege, SV; Sagare, AP; Wang, Y; Zhao, Z; Zlokovic, BV1
Abner, EL; Baldeshwiler, A; Bauer, B; Ding, Y; Hartz, AMS; Zhong, Y1
Basso, E; Pozzan, T; Rigotto, G; Zentilin, L1
Baker, JD; Becker, S; Blair, LJ; Darling, A; Dickey, CA; Favretto, F; Koren, J; Mandelkow, E; Martin, MD; Nordhues, BA; Sabbagh, JJ; Shelton, LB; Solanki, PK; Sullivan, LE; Sun, Z; Suntharalingam, A; Uversky, VN; Zheng, D; Zweckstetter, M1
Ballandonne, C; Bouet, V; Boulouard, M; Claeysen, S; Corvaisier, S; Cresteil, T; Dallemagne, P; Freret, T; Gaven, F; Giannoni, P; Hedou, D; Lecoutey, C; Malzert Fréon, A; Mignani, S; Rochais, C; Since, M1
Balbach, J; Baumann, M; Fändrich, M; Hause, G; Malesevic, M; Sachs, R; Schiene-Fischer, C; Villmow, M1
Asai, M; Iwata, N; Kawakubo, T; Kimura, S; Kinjo, A; Maruyama, K; Mori, R; Shirotani, K; Yagishita, S1
Emon, MA; Hofmann-Apitius, M; Karki, R; Kodamullil, AT; Younesi, E1
Curè, J; Flanagan, C; Kline, L1
Wang, J; Wang, Q1
Chang, KA; Choi, SH; Jeong, SJ; Kim, EM; Kim, HS; Lee, JH; Lee, JP; Park, CH; Seo, JH; Suh, YH; Wittendorp, MC1
Blalock, EM; Chen, KC; Kadish, I; Kraner, SD; Landfield, PW; Norris, CM; Porter, NM; Thibault, V1
Bennett, JP; Thiffault, C1
Cho, HJ; Huh, K; Jin, SM; Mook-Jung, I; Youn, HD1
Bennett, JP; Cassarino, DS; Parker, WD; Parks, JK; Swerdlow, RH1
Heinemann, U; Müller, W; Schuchmann, S1
Lee, RK; Wurtman, RJ1
Gong, CX; Grundke-Iqbal, I; Iqbal, K; Lidsky, T; Wegiel, J1
Chen, QS; Shimahara, T; Wei, WZ; Xie, CW1

Reviews

2 review(s) available for cyclosporine and Acute Confusional Senile Dementia

ArticleYear
Cerebral blindness.
    International ophthalmology clinics, 2009,Summer, Volume: 49, Issue:3

    Topics: Alzheimer Disease; Blindness, Cortical; Brain Diseases; Brain Injuries; Cerebral Infarction; Creutzfeldt-Jakob Syndrome; Cyclosporine; Electrodiagnosis; Humans; Immunosuppressive Agents; Occipital Lobe; Seizures; Tacrolimus; Visual Cortex

2009
Regulation of APP synthesis and secretion by neuroimmunophilin ligands and cyclooxygenase inhibitors.
    Annals of the New York Academy of Sciences, 2000, Volume: 920

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Cyclosporine; Gene Expression Regulation; Humans; Immunophilins; Immunosuppressive Agents; Ligands; Receptors, Cell Surface; Tacrolimus

2000

Other Studies

25 other study(ies) available for cyclosporine and Acute Confusional Senile Dementia

ArticleYear
Brain-penetrant, orally bioavailable microtubule-stabilizing small molecules are potential candidate therapeutics for Alzheimer's disease and related tauopathies.
    Journal of medicinal chemistry, 2014, Jul-24, Volume: 57, Issue:14

    Topics: Administration, Oral; Alzheimer Disease; Animals; Biological Availability; Brain; Cell Line; Humans; Mice; Microtubules; Molecular Structure; Pyrimidines; Tauopathies

2014
Discovery of benzimidazole derivatives as modulators of mitochondrial function: A potential treatment for Alzheimer's disease.
    European journal of medicinal chemistry, 2017, Jan-05, Volume: 125

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzimidazoles; Cognition; Humans; Ligands; Male; Membrane Potential, Mitochondrial; Memory; Mice, Transgenic; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Models, Molecular; Rats, Sprague-Dawley; Receptors, GABA

2017
Discovery of 1-(3-(benzyloxy)pyridin-2-yl)-3-(2-(piperazin-1-yl)ethyl)urea: A new modulator for amyloid beta-induced mitochondrial dysfunction.
    European journal of medicinal chemistry, 2017, Mar-10, Volume: 128

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Survival; Cells, Cultured; Cyclosporine; Drug Discovery; Hippocampus; Immunosuppressive Agents; Membrane Potential, Mitochondrial; Mice; Mitochondria; Mitochondrial Membrane Transport Proteins; Molecular Docking Simulation; Neurons; Piperazines; Protein Conformation; Urea

2017
Discovery of thienopyrrolotriazine derivatives to protect mitochondrial function against Aβ-induced neurotoxicity.
    European journal of medicinal chemistry, 2017, Dec-01, Volume: 141

    Topics: Adenosine Triphosphate; Alzheimer Disease; Amyloid beta-Peptides; Animals; Dogs; Dose-Response Relationship, Drug; Drug Discovery; Humans; Membrane Potential, Mitochondrial; Mice; Microsomes, Liver; Mitochondria; Molecular Structure; Neurons; Pyrroles; Rats; Structure-Activity Relationship; Triazines

2017
Synthesis and evaluation of 2-(3-arylureido)pyridines and 2-(3-arylureido)pyrazines as potential modulators of Aβ-induced mitochondrial dysfunction in Alzheimer's disease.
    European journal of medicinal chemistry, 2018, Jan-20, Volume: 144

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Cell Death; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Humans; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Molecular Docking Simulation; Molecular Structure; Pyrazines; Pyridines; Structure-Activity Relationship

2018
Pyrazinyl ureas revisited: 1-(3-(Benzyloxy)pyrazin-2-yl)-3-(3,4-dichlorophenyl)urea, a new blocker of Aβ-induced mPTP opening for Alzheimer's disease.
    European journal of medicinal chemistry, 2018, Sep-05, Volume: 157

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Ether-A-Go-Go Potassium Channels; Hippocampus; Humans; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Models, Molecular; Molecular Structure; Neural Stem Cells; Neuroprotective Agents; Pyrazines; Structure-Activity Relationship; Urea

2018
Novel use of FDA-approved drugs identified by cluster analysis of behavioral profiles.
    Scientific reports, 2022, 04-21, Volume: 12, Issue:1

    Topics: Alzheimer Disease; Animals; Calcineurin; Calcineurin Inhibitors; Cluster Analysis; Cyclosporine; Immunosuppressive Agents; Tacrolimus; Zebrafish

2022
Cyclosporine A (CsA) prevents synaptic impairment caused by truncated tau by caspase-3.
    Molecular and cellular neurosciences, 2023, Volume: 125

    Topics: Alzheimer Disease; Animals; Apoptosis; Caspase 3; Cyclosporine; Humans; Mice; Reactive Oxygen Species; tau Proteins

2023
Endothelial LRP1 protects against neurodegeneration by blocking cyclophilin A.
    The Journal of experimental medicine, 2021, 04-05, Volume: 218, Issue:4

    Topics: Alzheimer Disease; Animals; Blood-Brain Barrier; Cells, Cultured; Cognitive Dysfunction; Cyclophilin A; Cyclosporine; Disease Models, Animal; Endothelial Cells; Enzyme Inhibitors; Female; Gene Knockout Techniques; Genetic Therapy; Low Density Lipoprotein Receptor-Related Protein-1; Male; Matrix Metalloproteinase 9; Mice; Mice, Transgenic; Neurons; Signal Transduction

2021
Protecting P-glycoprotein at the blood-brain barrier from degradation in an Alzheimer's disease mouse model.
    Fluids and barriers of the CNS, 2021, Mar-06, Volume: 18, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Cyclosporine; Disease Models, Animal; Enzyme Inhibitors; Male; Mice; Mice, 129 Strain; Mice, Transgenic; Nocodazole; Tubulin Modulators

2021
Effects of Mild Excitotoxic Stimulus on Mitochondria Ca
    Cells, 2021, 08-10, Volume: 10, Issue:8

    Topics: Alzheimer Disease; Animals; Calcium; Cells, Cultured; Cyclosporine; Disease Models, Animal; Electron Transport; Glutamic Acid; Hippocampus; Ions; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; Neurotoxins; Reactive Oxygen Species

2021
Human cyclophilin 40 unravels neurotoxic amyloids.
    PLoS biology, 2017, Volume: 15, Issue:6

    Topics: alpha-Synuclein; Alzheimer Disease; Amyloid; Animals; Blotting, Western; Brain; Cognition Disorders; Cyclophilins; Cyclosporine; Disease Models, Animal; Female; HEK293 Cells; Humans; Male; Mice, Transgenic; Microscopy, Electron, Transmission; Neurodegenerative Diseases; Peptidyl-Prolyl Isomerase F; Protein Aggregates; Protein Aggregation, Pathological; tau Proteins; Tauopathies

2017
Design of donecopride, a dual serotonin subtype 4 receptor agonist/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Sep-09, Volume: 111, Issue:36

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Animals; Brain; Chlorocebus aethiops; Cholinesterase Inhibitors; Cognition; COS Cells; Cyclosporine; Drug Design; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Kinetics; Ligands; Mice; Permeability; Piperidines; Receptors, Serotonin, 5-HT4; Rhodamine 123; Serotonin 5-HT4 Receptor Agonists; Solubility; Task Performance and Analysis

2014
Inhibition of Aβ(1-40) fibril formation by cyclophilins.
    The Biochemical journal, 2016, 05-15, Volume: 473, Issue:10

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cyclophilin A; Cyclophilins; Cyclosporine; Enzyme Activation; Magnetic Resonance Spectroscopy; Mitochondria; Peptide Fragments; Peptidyl-Prolyl Isomerase F

2016
Perturbed Calcineurin-NFAT Signaling Is Associated with the Development of Alzheimer's Disease.
    Biological & pharmaceutical bulletin, 2016, Volume: 39, Issue:10

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Calcineurin; Calcineurin Inhibitors; Calcium Ionophores; Cell Line, Tumor; Cyclosporine; DNA-Binding Proteins; Down Syndrome; Humans; Intracellular Signaling Peptides and Proteins; Ionomycin; Luciferases; Muscle Proteins; Neprilysin; NFATC Transcription Factors; RNA, Messenger; Signal Transduction; tau Proteins; Tetradecanoylphorbol Acetate

2016
Using Drugs as Molecular Probes: A Computational Chemical Biology Approach in Neurodegenerative Diseases.
    Journal of Alzheimer's disease : JAD, 2017, Volume: 56, Issue:2

    Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Computational Biology; Computer Simulation; Cyclosporine; Donepezil; Drug Repositioning; Humans; Indans; Molecular Probes; Neuroprotective Agents; Piperidines; Riluzole; Structure-Activity Relationship

2017
Injection of bradykinin or cyclosporine A to hippocampus induces Alzheimer-like phosphorylation of Tau and abnormal behavior in rats.
    Chinese medical journal, 2002, Volume: 115, Issue:6

    Topics: Alzheimer Disease; Animals; Bradykinin; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cyclosporine; Disease Models, Animal; Hippocampus; Immunohistochemistry; Phosphorylation; Rats; Rats, Sprague-Dawley; tau Proteins

2002
Amyloid beta peptide induces cytochrome C release from isolated mitochondria.
    Neuroreport, 2002, Oct-28, Volume: 13, Issue:15

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Brain; Calcium Signaling; Caspase 3; Caspases; Cell Membrane Permeability; Cells, Cultured; Cyclosporine; Cytochrome c Group; Enzyme Inhibitors; Humans; Mice; Mitochondria; Neurons; Peptide Fragments

2002
Calcineurin triggers reactive/inflammatory processes in astrocytes and is upregulated in aging and Alzheimer's models.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2005, May-04, Volume: 25, Issue:18

    Topics: Adenoviridae; Age Factors; Aging; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Astrocytes; Calcineurin; Cells, Cultured; Cyclosporine; Disease Models, Animal; Enzyme Inhibitors; Fluorescent Antibody Technique; Genetic Vectors; Glial Fibrillary Acidic Protein; Immunohistochemistry; Inflammation; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microarray Analysis; Presenilin-1; Rats; Rats, Inbred F344; Up-Regulation

2005
Cyclical mitochondrial deltapsiM fluctuations linked to electron transport, F0F1 ATP-synthase and mitochondrial Na+/Ca+2 exchange are reduced in Alzheimer's disease cybrids.
    Mitochondrion, 2005, Volume: 5, Issue:2

    Topics: Alzheimer Disease; Cell Line; Cyclosporine; Electron Transport; Humans; Hybrid Cells; Membrane Potentials; Mitochondria; Mitochondrial Proton-Translocating ATPases; Sodium-Calcium Exchanger

2005
Disrupted intracellular calcium regulates BACE1 gene expression via nuclear factor of activated T cells 1 (NFAT 1) signaling.
    Aging cell, 2008, Volume: 7, Issue:2

    Topics: Active Transport, Cell Nucleus; Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Calcineurin; Calcineurin Inhibitors; Calcium; Calcium Signaling; Cells, Cultured; Chelating Agents; Cyclosporine; Disease Models, Animal; DNA-Binding Proteins; Egtazic Acid; Enzyme Activation; Humans; Ionophores; Mice; Neuroblastoma; NFATC Transcription Factors; Promoter Regions, Genetic; Up-Regulation

2008
Cyclosporin A increases resting mitochondrial membrane potential in SY5Y cells and reverses the depressed mitochondrial membrane potential of Alzheimer's disease cybrids.
    Biochemical and biophysical research communications, 1998, Jul-09, Volume: 248, Issue:1

    Topics: Alzheimer Disease; Atractyloside; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cyclosporine; DNA, Mitochondrial; Electron Transport Complex IV; Humans; Intracellular Membranes; Membrane Potentials; Mitochondria; Monoamine Oxidase; Onium Compounds; Organophosphorus Compounds; Sodium Azide; Tumor Cells, Cultured

1998
Altered Ca2+ signaling and mitochondrial deficiencies in hippocampal neurons of trisomy 16 mice: a model of Down's syndrome.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Sep-15, Volume: 18, Issue:18

    Topics: Aging; Alzheimer Disease; Animals; Calcium; Carcinogens; Cell Death; Cyclosporine; Diploidy; Disease Models, Animal; Down Syndrome; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Hippocampus; Karyotyping; Male; Membrane Potentials; Mice; Mice, Neurologic Mutants; Mitochondria; NADP; Neurons; Potassium; Quinoxalines; Signal Transduction; Trisomy; Vitamin E

1998
Metabolically active rat brain slices as a model to study the regulation of protein phosphorylation in mammalian brain.
    Brain research. Brain research protocols, 2001, Volume: 6, Issue:3

    Topics: Alzheimer Disease; Animals; Blotting, Western; Brain; Cyclosporine; Enzyme Inhibitors; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Male; Microtubule-Associated Proteins; Nuclear Proteins; Okadaic Acid; Organ Culture Techniques; Phosphorylation; Proteins; Rats; Rats, Wistar; RNA-Binding Proteins; tau Proteins

2001
Alzheimer amyloid beta-peptide inhibits the late phase of long-term potentiation through calcineurin-dependent mechanisms in the hippocampal dentate gyrus.
    Neurobiology of learning and memory, 2002, Volume: 77, Issue:3

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Calcineurin; Cyclosporine; Dentate Gyrus; Disease Models, Animal; Hippocampus; Immunosuppressive Agents; Long-Term Potentiation; Male; N-Methylaspartate; Phospholipids; Rats; Rats, Sprague-Dawley; Tacrolimus

2002