Page last updated: 2024-08-17

cycloserine and Dementia Praecox

cycloserine has been researched along with Dementia Praecox in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-19902 (5.13)18.7374
1990's14 (35.90)18.2507
2000's13 (33.33)29.6817
2010's8 (20.51)24.3611
2020's2 (5.13)2.80

Authors

AuthorsStudies
Deng, D; Ju, J; Wang, Z; Yan, R; Yao, L; Zhou, Q1
Billiras, RI; Dekeyne, A; Fone, KCF; Gobert, A; Millan, MJ; Rivet, JM; Sicard, DI; Watson, DJG1
Andrade, C; Kuppili, PP; Menon, V; Sarkar, S; Sathyanarayanan, G1
Asarnow, RF; Bachman, P; Forsyth, JK; Mathalon, DH; Roach, BJ; Ye, E1
Arima, K; Atsuta, H; Ishiwata, S; Ishiwata, Y; Itasaka, M; Kurumaji, A; Nakataki, M; Narushima, K; Nishikawa, T; Ohmori, T; Okazaki, M; Oshima, K; Shoda, K; Takiguchi, K; Tamaru, M; Tomita, M; Uezato, A; Yamamoto, N; Yasuhara, M1
Bello, I; Cain, CK; Creedon, T; Goff, DC; Laska, E; McCue, M; Tang, DI1
Goff, DC3
Goff, D1
Cather, C; Evins, AE; Goff, DC; Gottlieb, JD; Green, MF; Otto, MW; Raeke, L; Schoenfeld, D; Walsh, J1
Cather, C; Creedon, T; Goff, DC; Gottlieb, JD; Macklin, EA; Shanahan, M1
Heresco-Levy, U; Javitt, DC1
Angrist, B; Bugarski-Kirola, D; Corwin, J; Duncan, EJ; Efferen, TR; Gonzenbach, S; Kunzova, A; Negi, S; Peselow, E; Rotrosen, JP; Schwartz, MP; Stephanides, M; Szilagyi, S1
Evins, AE; Freudenreich, O; Goff, DC; Henderson, DC; Herz, L; Posever, T; Schoenfeld, D; Shih, V; Tsai, G; Yovel, I; Zhang, H1
Tiihonen, J; Tuominen, HJ; Wahlbeck, K1
Amico, E; Cohen, B; Coyle, JT; Goff, DC; Gruber, SA; Renshaw, PF; Silveri, MM; Yurgelun-Todd, DA1
Javitt, DC2
Buchanan, RW; Carpenter, WT; Gold, JM; Heresco-Levy, U; Javitt, DC; Marder, SR; McMahon, RP; Schooler, NR1
Hammonds, MD; Kee, BS; Shim, SS1
Coyle, JT; Goff, DC; Manoach, DS; Tsai, G1
Cascella, NG; Cavallini, C; Macciardi, F; Smeraldi, E1
Davis, RE; Deutsch, SI; Fay-McCarthy, M; Kendrick, K; Rosse, RB1
Coyle, JT; Darby, DG; Flood, J; Goff, DC; Manoach, DS; Tsai, G1
Hijman, R; Kahn, RS; van Berckel, BN; van der Linden, JA; van Ree, JM; Westenberg, HG1
Blankenstein, MA; Gispen-de Wied, C; Kahn, RS; Lipsch, C; van Berckel, BN; van Ree, JM; Wynne, HJ1
Semba, J1
Farber, NB; Newcomer, JW; Olney, JW1
Amico, E; Coyle, JT; Goff, DC; Hayden, DL; Levitt, J; Manoach, D; McCarley, R; Schoenfeld, DA; Tsai, G1
Amico, E; Evins, AE; Goff, DC; Henderson, DC1
Evenblij, CN; Kahn, RS; Maas, MF; van Berckel, BN; van der Geld, MA; van Loon, BJ; van Ree, JM; Wynne, HJ1
Bergeron, R; Coyle, JT; Greene, R; Grunze, H; McCarley, R1
Carpenter, WT1
Ermilov, M; Heresco-Levy, U; Javitt, DC; Shapira, B; Shimoni, J; Silipo, G1
Engberg, G; Erhardt, S1
Amico, E; Evins, AE; Goff, DC; Posever, TA; Toker, R1
Van Kammen, DP1
Fink, M; Itil, TM; Ponce, D; Simeon, J1

Reviews

11 review(s) available for cycloserine and Dementia Praecox

ArticleYear
Efficacy of adjunctive D-Cycloserine for the treatment of schizophrenia: a systematic review and meta-analysis of randomized controlled trials.
    Journal of neural transmission (Vienna, Austria : 1996), 2021, Volume: 128, Issue:2

    Topics: Antipsychotic Agents; Cycloserine; Drug Therapy, Combination; Humans; Randomized Controlled Trials as Topic; Schizophrenia

2021
D-cycloserine in Schizophrenia: New Strategies for Improving Clinical Outcomes by Enhancing Plasticity.
    Current neuropharmacology, 2017, Volume: 15, Issue:1

    Topics: Animals; Antipsychotic Agents; Cycloserine; Humans; Neuronal Plasticity; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Treatment Outcome

2017
The Therapeutic Role of d-Cycloserine in Schizophrenia.
    Advances in pharmacology (San Diego, Calif.), 2016, Volume: 76

    Topics: Cognitive Behavioral Therapy; Cycloserine; Humans; Memory; Receptors, N-Methyl-D-Aspartate; Schizophrenia

2016
D-cycloserine: an evolving role in learning and neuroplasticity in schizophrenia.
    Schizophrenia bulletin, 2012, Volume: 38, Issue:5

    Topics: Affect; Animals; Arousal; Brain; Cognitive Behavioral Therapy; Combined Modality Therapy; Cycloserine; Disability Evaluation; Disease Models, Animal; Drug Administration Schedule; Humans; Learning; Magnetic Resonance Imaging; Memory; Memory, Short-Term; Motivation; Neuronal Plasticity; Quality of Life; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology

2012
Effects of D-cycloserine on negative symptoms in schizophrenia.
    Schizophrenia research, 2004, Dec-01, Volume: 71, Issue:2-3

    Topics: Affect; Antimetabolites; Antipsychotic Agents; Cognition Disorders; Cycloserine; Diagnostic and Statistical Manual of Mental Disorders; Double-Blind Method; Drug Administration Schedule; Glycine; Humans; Male; Middle Aged; Neuropsychological Tests; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Severity of Illness Index

2004
Glutamatergic drugs for schizophrenia: a systematic review and meta-analysis.
    Schizophrenia research, 2005, Jan-01, Volume: 72, Issue:2-3

    Topics: Clozapine; Cycloserine; Dioxoles; Drug Synergism; Drug Therapy, Combination; Excitatory Amino Acid Agents; Glycine; Humans; Hydro-Lyases; Molindone; Piperidines; Schizophrenia

2005
Is the glycine site half saturated or half unsaturated? Effects of glutamatergic drugs in schizophrenia patients.
    Current opinion in psychiatry, 2006, Volume: 19, Issue:2

    Topics: Antimetabolites; Antipsychotic Agents; Clozapine; Cycloserine; Drug Therapy, Combination; Glutamic Acid; Glycine; Humans; Receptors, N-Methyl-D-Aspartate; Sarcosine; Schizophrenia

2006
Potentiation of the NMDA receptor in the treatment of schizophrenia: focused on the glycine site.
    European archives of psychiatry and clinical neuroscience, 2008, Volume: 258, Issue:1

    Topics: Acetamides; Alanine; Antipsychotic Agents; Clozapine; Cognition; Cycloserine; Dopamine Agents; Drug Synergism; Drug Therapy, Combination; Glycine; Glycine Agents; Glycine Plasma Membrane Transport Proteins; Humans; Monoamine Oxidase Inhibitors; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Sarcosine; Schizophrenia; Schizophrenic Psychology; Serine

2008
[Glycine therapy of schizophrenia; its rationale and a review of clinical trials].
    Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology, 1998, Volume: 18, Issue:3

    Topics: Acetamides; Alanine; Amino Acid Transport Systems, Neutral; Animals; Carrier Proteins; Cycloserine; Glutamic Acid; Glycine; Glycine Plasma Membrane Transport Proteins; Humans; Prodrugs; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Serine

1998
Glycine agonists: what can they teach us about schizophrenia?
    Archives of general psychiatry, 1999, Volume: 56, Issue:1

    Topics: Adolescent; Adult; Animals; Brain; Child; Clinical Trials as Topic; Cycloserine; Glycine; Humans; Rats; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology

1999
Treatment of negative and cognitive symptoms.
    Current psychiatry reports, 1999, Volume: 1, Issue:1

    Topics: Antimetabolites; Antipsychotic Agents; Cognition Disorders; Cycloserine; Glycine; Humans; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology; Serine; Treatment Outcome

1999

Trials

20 trial(s) available for cycloserine and Dementia Praecox

ArticleYear
Effects of Augmenting N-Methyl-D-Aspartate Receptor Signaling on Working Memory and Experience-Dependent Plasticity in Schizophrenia: An Exploratory Study Using Acute d-cycloserine.
    Schizophrenia bulletin, 2017, 09-01, Volume: 43, Issue:5

    Topics: Adolescent; Adult; Cognitive Dysfunction; Cycloserine; Double-Blind Method; Electroencephalography; Evoked Potentials, Visual; Female; Humans; Male; Memory, Short-Term; Neuronal Plasticity; Nootropic Agents; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Signal Transduction; Young Adult

2017
Association of schizophrenia onset age and white matter integrity with treatment effect of D-cycloserine: a randomized placebo-controlled double-blind crossover study.
    BMC psychiatry, 2017, 07-12, Volume: 17, Issue:1

    Topics: Adult; Age of Onset; Antipsychotic Agents; Cross-Over Studies; Cycloserine; Diffusion Tensor Imaging; Double-Blind Method; Drug Therapy, Combination; Female; Glycine Agents; Humans; Male; Middle Aged; Schizophrenia; Schizophrenic Psychology; White Matter

2017
d-Cycloserine augmentation of cognitive remediation in schizophrenia.
    Schizophrenia research, 2014, Volume: 153, Issue:1-3

    Topics: Acoustic Stimulation; Adult; Antimetabolites; Cognition Disorders; Cognitive Behavioral Therapy; Cycloserine; Discrimination, Psychological; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales; Schizophrenia; Single-Blind Method

2014
Once-weekly D-cycloserine effects on negative symptoms and cognition in schizophrenia: an exploratory study.
    Schizophrenia research, 2008, Volume: 106, Issue:2-3

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Cognition Disorders; Cycloserine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Placebos; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology

2008
D-cycloserine facilitation of cognitive behavioral therapy for delusions in schizophrenia.
    Schizophrenia research, 2011, Volume: 131, Issue:1-3

    Topics: Adolescent; Adult; Aged; Antimetabolites; Cognitive Behavioral Therapy; Culture; Cycloserine; Delusions; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Psychotic Disorders; Retrospective Studies; Schizophrenia; Young Adult

2011
Comparative effects of glycine and D-cycloserine on persistent negative symptoms in schizophrenia: a retrospective analysis.
    Schizophrenia research, 2004, Feb-01, Volume: 66, Issue:2-3

    Topics: Adult; Antimetabolites; Antipsychotic Agents; Chlorpromazine; Cycloserine; Female; Glycine; Humans; Male; Middle Aged; Receptors, N-Methyl-D-Aspartate; Retrospective Studies; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index; Synaptic Transmission

2004
Effects of D-cycloserine on negative symptoms in schizophrenia.
    Schizophrenia research, 2004, Dec-01, Volume: 71, Issue:2-3

    Topics: Affect; Antimetabolites; Antipsychotic Agents; Cognition Disorders; Cycloserine; Diagnostic and Statistical Manual of Mental Disorders; Double-Blind Method; Drug Administration Schedule; Glycine; Humans; Male; Middle Aged; Neuropsychological Tests; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Severity of Illness Index

2004
A six-month, placebo-controlled trial of D-cycloserine co-administered with conventional antipsychotics in schizophrenia patients.
    Psychopharmacology, 2005, Volume: 179, Issue:1

    Topics: Adult; Antipsychotic Agents; Cycloserine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Schizophrenia; Treatment Outcome

2005
Functional magnetic resonance imaging studies of schizophrenic patients during word production: effects of D-cycloserine.
    Psychiatry research, 2005, Jan-30, Volume: 138, Issue:1

    Topics: Antipsychotic Agents; Cerebral Cortex; Cycloserine; Diagnostic and Statistical Manual of Mental Disorders; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Magnetic Resonance Imaging; Male; Schizophrenia; Speech; Temporal Lobe; Verbal Behavior; Vocabulary

2005
The Cognitive and Negative Symptoms in Schizophrenia Trial (CONSIST): the efficacy of glutamatergic agents for negative symptoms and cognitive impairments.
    The American journal of psychiatry, 2007, Volume: 164, Issue:10

    Topics: Adolescent; Adult; Cognition Disorders; Cycloserine; Double-Blind Method; Excitatory Amino Acid Agents; Female; Follow-Up Studies; Glycine; Humans; Male; Middle Aged; Neuropsychological Tests; Placebos; Psychiatric Status Rating Scales; Psychotic Disorders; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index; Treatment Outcome

2007
Dose-finding trial of D-cycloserine added to neuroleptics for negative symptoms in schizophrenia.
    The American journal of psychiatry, 1995, Volume: 152, Issue:8

    Topics: Adult; Antipsychotic Agents; Cycloserine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Excitatory Amino Acid Agonists; Female; Humans; Male; Nootropic Agents; Psychiatric Status Rating Scales; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology; Treatment Outcome

1995
D-cycloserine adjuvant therapy to molindone in the treatment of schizophrenia.
    Clinical neuropharmacology, 1996, Volume: 19, Issue:5

    Topics: Administration, Oral; Adult; Aged; Antipsychotic Agents; Chemotherapy, Adjuvant; Cycloserine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Middle Aged; Molindone; N-Methylaspartate; Psychiatric Status Rating Scales; Schizophrenia

1996
D-cycloserine added to clozapine for patients with schizophrenia.
    The American journal of psychiatry, 1996, Volume: 153, Issue:12

    Topics: Adult; Ambulatory Care; Amino Acids; Clozapine; Cycloserine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Humans; Male; Placebos; Psychiatric Status Rating Scales; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology; Treatment Outcome

1996
Efficacy and tolerance of D-cycloserine in drug-free schizophrenic patients.
    Biological psychiatry, 1996, Dec-15, Volume: 40, Issue:12

    Topics: Adolescent; Adult; Antipsychotic Agents; Cycloserine; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Single-Blind Method

1996
The partial NMDA agonist D-cycloserine stimulates LH secretion in healthy volunteers.
    Psychopharmacology, 1998, Volume: 138, Issue:2

    Topics: Adult; Affect; Antipsychotic Agents; Behavior; Blood Pressure; Body Temperature; Brief Psychiatric Rating Scale; Cross-Over Studies; Cycloserine; Dopamine; Double-Blind Method; Heart Rate; Homovanillic Acid; Humans; Hydrocortisone; Luteinizing Hormone; Male; N-Methylaspartate; Neurosecretory Systems; Receptors, N-Methyl-D-Aspartate; Schizophrenia

1998
A placebo-controlled trial of D-cycloserine added to conventional neuroleptics in patients with schizophrenia.
    Archives of general psychiatry, 1999, Volume: 56, Issue:1

    Topics: Adult; Amino Acids; Antipsychotic Agents; Cycloserine; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glycine; Humans; Male; Middle Aged; Neuropsychological Tests; Placebos; Psychiatric Status Rating Scales; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Treatment Outcome

1999
A placebo-controlled crossover trial of D-cycloserine added to clozapine in patients with schizophrenia.
    Biological psychiatry, 1999, Feb-15, Volume: 45, Issue:4

    Topics: Adult; Antipsychotic Agents; Behavioral Symptoms; Clozapine; Cross-Over Studies; Cycloserine; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Excitatory Amino Acid Agonists; Female; Humans; Male; Psychiatric Status Rating Scales; Schizophrenia; Treatment Outcome

1999
D-cycloserine increases positive symptoms in chronic schizophrenic patients when administered in addition to antipsychotics: a double-blind, parallel, placebo-controlled study.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1999, Volume: 21, Issue:2

    Topics: Adult; Antimetabolites; Antipsychotic Agents; Cycloserine; Double-Blind Method; Drug Therapy, Combination; Female; Glycine; Humans; Luteinizing Hormone; Male; Middle Aged; Placebos; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology

1999
Placebo-controlled trial of D-cycloserine added to conventional neuroleptics, olanzapine, or risperidone in schizophrenia.
    The American journal of psychiatry, 2002, Volume: 159, Issue:3

    Topics: Adult; Antibiotics, Antitubercular; Antipsychotic Agents; Benzodiazepines; Cross-Over Studies; Cycloserine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Olanzapine; Pirenzepine; Placebo Effect; Placebos; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome

2002
D-Cycloserine added to risperidone in patients with primary negative symptoms of schizophrenia.
    Schizophrenia research, 2002, Jul-01, Volume: 56, Issue:1-2

    Topics: Adult; Antipsychotic Agents; Cycloserine; Depression; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Risperidone; Schizophrenia; Schizophrenic Psychology; Treatment Outcome

2002

Other Studies

9 other study(ies) available for cycloserine and Dementia Praecox

ArticleYear
The impact of D-cycloserine and sarcosine on in vivo frontal neural activity in a schizophrenia-like model.
    BMC psychiatry, 2019, 10-25, Volume: 19, Issue:1

    Topics: Animals; Cycloserine; Disease Models, Animal; Frontal Lobe; Glycine Plasma Membrane Transport Proteins; Mice; Receptors, N-Methyl-D-Aspartate; Sarcosine; Schizophrenia

2019
Comparative Pro-cognitive and Neurochemical Profiles of Glycine Modulatory Site Agonists and Glycine Reuptake Inhibitors in the Rat: Potential Relevance to Cognitive Dysfunction and Its Management.
    Molecular neurobiology, 2020, Volume: 57, Issue:5

    Topics: Amino Acids; Animals; Autism Spectrum Disorder; Cognition; Cognition Disorders; Cycloserine; Dose-Response Relationship, Drug; Freezing Reaction, Cataleptic; Glycine; Glycine Agents; Male; Memory, Short-Term; Motor Activity; Neurotransmitter Uptake Inhibitors; Nootropic Agents; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Recognition, Psychology; Sarcosine; Schizophrenia; Scopolamine; Serine; Social Behavior

2020
d-cycloserine adjuvant therapy to conventional neuroleptic treatment in schizophrenia: an open-label study.
    Journal of neural transmission. General section, 1994, Volume: 95, Issue:2

    Topics: Adult; Antipsychotic Agents; Brief Psychiatric Rating Scale; Cycloserine; Dopamine; Drug Interactions; Female; Humans; Male; Phencyclidine; Psychoses, Substance-Induced; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology

1994
What is the role of glutamate in schizophrenia?
    The Harvard mental health letter, 1999, Volume: 15, Issue:10

    Topics: Cycloserine; Glutamic Acid; Glycine; Humans; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Schizophrenia

1999
Short-term and long-term effects of N-methyl-D-aspartate receptor hypofunction.
    Archives of general psychiatry, 2000, Volume: 57, Issue:12

    Topics: Cycloserine; Humans; Models, Neurological; Presynaptic Terminals; Psychotic Disorders; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology; Synaptic Transmission

2000
New style clinical trials in schizophrenia.
    Current psychiatry reports, 1999, Volume: 1, Issue:1

    Topics: Antimetabolites; Clinical Trials as Topic; Cycloserine; Glycine; Humans; Research Design; Schizophrenia; Schizophrenic Psychology; Treatment Outcome

1999
Increased phasic activity of dopaminergic neurones in the rat ventral tegmental area following pharmacologically elevated levels of endogenous kynurenic acid.
    Acta physiologica Scandinavica, 2002, Volume: 175, Issue:1

    Topics: Action Potentials; Animals; Antimetabolites; Butyrates; Cycloserine; Dizocilpine Maleate; Dopamine; Excitatory Amino Acid Antagonists; Kynurenic Acid; Male; Neurons; Rats; Rats, Sprague-Dawley; Schizophrenia; Ventral Tegmental Area

2002
gamma-Aminobutyric acid (Gaba) and the dopamine hypothesis of schizophrenia.
    The American journal of psychiatry, 1977, Volume: 134, Issue:2

    Topics: Aminobutyrates; Aminooxyacetic Acid; Blood-Brain Barrier; Brain; Cycloserine; Dopamine; GABA Antagonists; gamma-Aminobutyric Acid; Humans; Monoamine Oxidase Inhibitors; Receptors, Dopamine; Receptors, Drug; Research Design; Schizophrenia

1977
d-Cycloserine therapy of psychosis by symptom provocation.
    Comprehensive psychiatry, 1970, Volume: 11, Issue:1

    Topics: Adult; Behavior; Central Nervous System; Chronic Disease; Cycloserine; Electroencephalography; Female; Humans; Male; Middle Aged; Schizophrenia

1970