cyclopentolate has been researched along with Retrolental Fibroplasia in 19 studies
Cyclopentolate: A parasympatholytic anticholinergic used solely to obtain mydriasis or cycloplegia.
cyclopentolate : A carboxylic ester resulting from the formal condensation of (1-hydroxycyclopentyl)(phenyl)acetic acid with N,N-dimethylethanolamine. A tertiary amine antimuscarinic with actions similar to atropine, it is used as its hydrochloride salt to produce mydriasis (excessive dilation of the pupil) and cycloplegia (paralysis of the ciliary muscle of the eye) for opthalmic diagnostic procedures. It acts more quickly than atropine and has a shorter duration of action.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Preterm infants undergoing Retinopathy of Prematurity Eye Exams (ROPEE) may experience adverse events, possibly from systemic absorption of cyclopentolate." | 9.22 | Systemic Absorption of Cyclopentolate and Adverse Events After Retinopathy of Prematurity Exams. ( Erickson, SW; Hall, RW; Hendrickson, H; Lowery, S; Mitchell, A; Yates, C, 2016) |
| "We report for the first time, to our knowledge, the acquisition of noncontact ultra-wide-field oral fluorescein angiograms in premature infants with retinopathy of prematurity." | 7.80 | Noncontact high-resolution ultra-wide-field oral fluorescein angiography in premature infants with retinopathy of prematurity. ( Fung, TH; Mordant, DJ; Muqit, MM; Patel, CK; Smith, LM, 2014) |
| "Cyclopentolate is standardly used in ophthalmologic examinations of neonates to facilitate screening for retinopathy of prematurity." | 7.80 | Systemic effects of ophthalmic cyclopentolate on body weight in neonatal mice. ( El-Remessy, AB; Goei, S; Manasco, KB; Matragoon, S; Rozette, NA; Sethi, S, 2014) |
| "Preterm infants undergoing Retinopathy of Prematurity Eye Exams (ROPEE) may experience adverse events, possibly from systemic absorption of cyclopentolate." | 5.22 | Systemic Absorption of Cyclopentolate and Adverse Events After Retinopathy of Prematurity Exams. ( Erickson, SW; Hall, RW; Hendrickson, H; Lowery, S; Mitchell, A; Yates, C, 2016) |
| " Caffeine is frequently used for apnea of prematurity." | 3.83 | Atrial arrhythmia after newborn eye exam, to caffeine or not to caffeine? ( Ahmad, A; Klein, B; Mondal, T, 2016) |
| "We report for the first time, to our knowledge, the acquisition of noncontact ultra-wide-field oral fluorescein angiograms in premature infants with retinopathy of prematurity." | 3.80 | Noncontact high-resolution ultra-wide-field oral fluorescein angiography in premature infants with retinopathy of prematurity. ( Fung, TH; Mordant, DJ; Muqit, MM; Patel, CK; Smith, LM, 2014) |
| "Cyclopentolate is standardly used in ophthalmologic examinations of neonates to facilitate screening for retinopathy of prematurity." | 3.80 | Systemic effects of ophthalmic cyclopentolate on body weight in neonatal mice. ( El-Remessy, AB; Goei, S; Manasco, KB; Matragoon, S; Rozette, NA; Sethi, S, 2014) |
| "A 2-month-old girl who had been born at 27-weeks' gestation was admitted for her screening examination for retinopathy of prematurity and given two drops each of cyclopentolate 0." | 3.71 | Acute gastric dilatation complicating the use of mydriatics in a preterm newborn. ( Sarici, SU; Unal, S; Yurdakök, M, 2001) |
| " These agents are rarely absorbed to systemic circulation and in some cases result with serious side effects like skin rash, tachycardia, feeding intolerance, discomfort, apnea, gastric dilatation and ileus, despite different treatment models and dosage reducing strategies." | 1.40 | Fatal necrotising enterocolitis due to mydriatic eye drops. ( Demet, T; Mehmet, Y; Murat, S; Nilgun, K; Ozge, KA; Ozgun, U; Zafer, D, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (10.53) | 18.7374 |
| 1990's | 2 (10.53) | 18.2507 |
| 2000's | 2 (10.53) | 29.6817 |
| 2010's | 10 (52.63) | 24.3611 |
| 2020's | 3 (15.79) | 2.80 |
| Authors | Studies |
|---|---|
| Kremer, LJ | 2 |
| Medlicott, N | 2 |
| Sime, MJ | 3 |
| Broadbent, R | 3 |
| Edmonds, L | 2 |
| Berry, MJ | 1 |
| Austin, NC | 1 |
| Alsweiler, JM | 1 |
| Reith, DM | 2 |
| McCaffrey, F | 1 |
| Kremer, L | 1 |
| Reith, D | 1 |
| Medlicott, NJ | 1 |
| Moshfeghi, DM | 1 |
| Silva, RA | 1 |
| Berrocal, AM | 1 |
| Fung, TH | 1 |
| Muqit, MM | 1 |
| Mordant, DJ | 1 |
| Smith, LM | 1 |
| Patel, CK | 1 |
| Lee, JM | 1 |
| Kodsi, SR | 1 |
| Gaffar, MA | 1 |
| Rubin, SE | 1 |
| Rozette, NA | 1 |
| Matragoon, S | 1 |
| Sethi, S | 1 |
| Goei, S | 1 |
| Manasco, KB | 1 |
| El-Remessy, AB | 1 |
| Ozgun, U | 1 |
| Demet, T | 1 |
| Ozge, KA | 1 |
| Zafer, D | 1 |
| Murat, S | 1 |
| Mehmet, Y | 1 |
| Nilgun, K | 1 |
| Fledelius, HC | 1 |
| Bangsgaard, R | 1 |
| Slidsborg, C | 1 |
| laCour, M | 1 |
| Mitchell, A | 1 |
| Hall, RW | 1 |
| Erickson, SW | 1 |
| Yates, C | 1 |
| Lowery, S | 1 |
| Hendrickson, H | 1 |
| Ahmad, A | 1 |
| Mondal, T | 1 |
| Klein, B | 1 |
| Punyawattanaporn, A | 1 |
| Tengtrisorn, S | 1 |
| Sangsupawanich, P | 1 |
| Derinoz, O | 1 |
| Emeksiz, HC | 1 |
| Vicente, GV | 1 |
| Bahri, M | 1 |
| Palafoutas, JJ | 1 |
| Wang, H | 1 |
| Mehta, N | 1 |
| Isenberg, S | 1 |
| Everett, S | 1 |
| Parelhoff, E | 1 |
| Wheatcroft, S | 1 |
| Sharma, A | 1 |
| McAllister, J | 1 |
| Laws, DE | 1 |
| Morton, C | 1 |
| Weindling, M | 1 |
| Clark, D | 1 |
| Sarici, SU | 1 |
| Yurdakök, M | 1 |
| Unal, S | 1 |
| LaRoche, GR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficiency and Safety of Phenylephrine and Tropicamide Used in Premature Retinopathy[NCT03448640] | 60 participants (Actual) | Observational | 2016-01-15 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 trials available for cyclopentolate and Retrolental Fibroplasia
| Article | Year |
|---|---|
Low dose or very low dose phenylephrine and cyclopentolate microdrops for retinopathy of prematurity eye examinations (The Little Eye Drop Study): a randomised controlled non-inferiority trial.
Topics: Birth Weight; Cyclopentolate; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, Very Low B | 2023 |
Randomised controlled pilot trial comparing low dose and very low- dose microdrop administration of phenylephrine and cyclopentolate for retinopathy of prematurity eye examinations in neonates.
Topics: Administration, Ophthalmic; Cyclopentolate; Dose-Response Relationship, Drug; Female; Humans; Infant | 2021 |
Systemic Absorption of Cyclopentolate and Adverse Events After Retinopathy of Prematurity Exams.
Topics: Absorption, Physiological; Chromatography, Liquid; Cyclopentolate; Female; Follow-Up Studies; Gestat | 2016 |
A randomized controlled trial to determine the lowest effective dose for adequate mydriasis in premature infants.
Topics: Cyclopentolate; Drug Combinations; Female; Gestational Age; Humans; Infant, Newborn; Infant, Prematu | 2012 |
Reduction in mydriatic drop size in premature infants.
Topics: Cyclopentolate; Drug Administration Schedule; Drug Combinations; Female; Humans; Infant; Infant, New | 1993 |
14 other studies available for cyclopentolate and Retrolental Fibroplasia
| Article | Year |
|---|---|
A Survey of Neonatal Nurses on Mydriatic Regimens Used in Neonatal Retinopathy of Prematurity Eye Examinations.
Topics: Australia; Cross-Sectional Studies; Cyclopentolate; Drug-Related Side Effects and Adverse Reactions; | 2022 |
Exudative retinal detachment following photocoagulation in older premature infants for retinopathy of prematurity: description and management.
Topics: Administration, Topical; Cyclopentolate; Exudates and Transudates; Gestational Age; History, Ancient | 2014 |
Noncontact high-resolution ultra-wide-field oral fluorescein angiography in premature infants with retinopathy of prematurity.
Topics: Administration, Oral; Cyclopentolate; Female; Fluorescein; Fluorescein Angiography; Fluorescent Dyes | 2014 |
Cardiopulmonary arrest following administration of Cyclomydril eyedrops for outpatient retinopathy of prematurity screening.
Topics: Cardiopulmonary Resuscitation; Cyclopentolate; Drug Combinations; Female; Gestational Age; Heart Arr | 2014 |
Systemic effects of ophthalmic cyclopentolate on body weight in neonatal mice.
Topics: Administration, Ophthalmic; Animals; Animals, Newborn; Body Weight; Cyclopentolate; Eating; Mice, In | 2014 |
Fatal necrotising enterocolitis due to mydriatic eye drops.
Topics: Blood Pressure; Cyclopentolate; Enterocolitis, Necrotizing; Fatal Outcome; Gestational Age; Humans; | 2014 |
The usefulness of the Retinomax autorefractor for childhood screening validated against a Danish preterm cohort examined at the age of 4 years.
Topics: Amblyopia; Anisometropia; Child, Preschool; Cyclopentolate; Denmark; Female; Gestational Age; Humans | 2015 |
Atrial arrhythmia after newborn eye exam, to caffeine or not to caffeine?
Topics: Apnea; Atrial Premature Complexes; Bradycardia; Caffeine; Central Nervous System Stimulants; Cyclope | 2016 |
Pupil dilatation after single and triple doses of mydriatic agent in preterm infants.
Topics: Cyclopentolate; Female; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Male; Mydriatic | 2009 |
Use of physostigmine for cyclopentolate overdose in an infant.
Topics: Antidotes; Cholinergic Antagonists; Cyclopentolate; Drug Overdose; Female; Humans; Infant; Infant, N | 2012 |
A comparison of mydriatic eyedrops in low-weight infants.
Topics: Blood Pressure; Cyclopentolate; Drug Combinations; Humans; Infant, Low Birth Weight; Infant, Newborn | 1984 |
Systemic effects of screening for retinopathy of prematurity.
Topics: Anesthetics, Local; Blood Gas Analysis; Blood Pressure; Cyclopentolate; Female; Humans; Infant; Infa | 1996 |
Acute gastric dilatation complicating the use of mydriatics in a preterm newborn.
Topics: Acute Disease; Cyclopentolate; Female; Gastric Dilatation; Humans; Infant; Infant, Newborn; Infant, | 2001 |
Safety of ocular drugs in pediatrics.
Topics: Cyclopentolate; Humans; Infant; Infant, Newborn; Mydriatics; Phenylephrine; Pupil; Retinopathy of Pr | 1987 |