Page last updated: 2024-10-25

cyclopentolate and Myopia

cyclopentolate has been researched along with Myopia in 37 studies

Cyclopentolate: A parasympatholytic anticholinergic used solely to obtain mydriasis or cycloplegia.
cyclopentolate : A carboxylic ester resulting from the formal condensation of (1-hydroxycyclopentyl)(phenyl)acetic acid with N,N-dimethylethanolamine. A tertiary amine antimuscarinic with actions similar to atropine, it is used as its hydrochloride salt to produce mydriasis (excessive dilation of the pupil) and cycloplegia (paralysis of the ciliary muscle of the eye) for opthalmic diagnostic procedures. It acts more quickly than atropine and has a shorter duration of action.

Myopia: A refractive error in which rays of light entering the EYE parallel to the optic axis are brought to a focus in front of the RETINA when accommodation (ACCOMMODATION, OCULAR) is relaxed. This results from an overly curved CORNEA or from the eyeball being too long from front to back. It is also called nearsightedness.

Research Excerpts

ExcerptRelevanceReference
"We treated a case of transient myopia in a patient being treated with hydrochlorothiazide and triamterene for tinnitus."7.69Choroidal effusion as a mechanism for transient myopia induced by hydrochlorothiazide and triamterene. ( Feldon, SE; Green, RL; Söylev, MF, 1995)
"We studied intraocular pressure (IOP) in a group of healthy myopic subjects before and after administration of chlorhydrate cyclopentolate 1%."5.08Changes in intraocular pressure due to cycloplegia. ( Bermudez Rodriguez, F; Eiroa Mozos, P; Garcia Sanchez, J; Velasco Cabrera, J, 1998)
"In order to normalize the condition of pseudomyopia, the following can be summarized: One percent cyclopentolate was effective in 63%, and 0."5.06Myopia prevention and therapy. The role of pharmaceutical agents. Japanese studies. ( Hosaka, A, 1988)
"Eyes treated with pilocarpine developed approximately 6D myopia (p < 0."3.81Effects of muscarinic receptor modulators on ocular biometry of guinea pigs. ( Fang, F; Huang, F; Li, C; Liu, Y; Qu, J; Xie, R; Zhou, X; Zhu, Y, 2015)
"19 D less myopia, tropicamide induced 0."3.71[Aberrometry due dilated pupils--Which mydriatic should be used?]. ( Duncker, GI; Giessler, S; Hammer, T, 2002)
"We treated a case of transient myopia in a patient being treated with hydrochlorothiazide and triamterene for tinnitus."3.69Choroidal effusion as a mechanism for transient myopia induced by hydrochlorothiazide and triamterene. ( Feldon, SE; Green, RL; Söylev, MF, 1995)
"Cyclopentolate was more effective than tropicamide in reducing accommodative amplitude in adult myopes (near-point testing)."2.71Comparison of tropicamide and cyclopentolate for cycloplegic refractions in myopic adult refractive surgery patients. ( Hofmeister, EM; Kaupp, SE; Schallhorn, SC, 2005)
" Since long-term use of corticosteroids to maintain the initial beneficial effect on refraction would be unacceptable, we conclude that these agents should not be used after photorefractive keratectomy."2.67The effect of topical corticosteroids on refractive outcome and corneal haze after photorefractive keratectomy. A prospective, randomized, double-blind trial. ( Gartry, DS; Lohmann, CP; Marshall, J; Muir, MG, 1992)
"The most likely effective treatment to slow myopia progression thus far is anti-muscarinic topical medication."2.47Interventions to slow progression of myopia in children. ( Cotter, SA; Lindsley, K; Mutti, DO; Twelker, JD; Vedula, SS; Walline, JJ, 2011)
"When hyperopia was defined as SE of more than 0."1.43Pre- and Postcycloplegic Refractions in Children and Adolescents. ( Guo, K; Guo, Y; Jing, X; Pan, CW; Wang, Y; Yang, D; Yang, X; Zhu, D, 2016)
"Mild hyperopia was the most prevalent category at all ages, except for Mahabubnagar where emmetropia became the marginally most prevalent category at ages 14 and 15."1.36Is emmetropia the natural endpoint for human refractive development? An analysis of population-based data from the refractive error study in children (RESC). ( Ellwein, LB; Morgan, IG; Rose, KA, 2010)
"Cyclopentolate 1% was used to obtain cycloplegia."1.28Autosomal recessive inheritance of myopia in Hong Kong Chinese infants. ( Edwards, M; Lewis, WH, 1991)

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19904 (10.81)18.7374
1990's10 (27.03)18.2507
2000's5 (13.51)29.6817
2010's12 (32.43)24.3611
2020's6 (16.22)2.80

Authors

AuthorsStudies
Li, SM1
Kang, MT1
Li, L1
Wei, SF1
He, X1
Liu, LR1
Li, H1
Wang, NL1
Hasrod, N1
Rubin, A1
Senoo, Y1
Furuse, T1
Hasebe, S1
Mutti, DO2
Sinnott, LT1
Zadnik, K1
Ocak, OB1
Inal, A1
Tülü Aygün, B1
Kırmacı Kabakci, A1
Kemer Atik, B1
Yurttaser Ocak, S1
Gökyiğit, B1
Vagge, A1
Del Noce, C1
Pellegrini, M1
Cappelli, F1
Musolino, M1
Bernabei, F1
Giannaccare, G1
Traverso, CE1
Guo, X1
Fu, M1
Ding, X1
Morgan, IG3
Zeng, Y1
He, M1
Zhou, J1
Pan, M1
Chen, G1
Zhen, J1
Xie, R2
Lu, F1
Qu, J2
Hiraoka, T1
Miyata, K1
Nakamura, Y1
Ogata, M1
Okamoto, F1
Oshika, T1
Fang, F1
Huang, F1
Li, C1
Liu, Y1
Zhu, Y1
Zhou, X1
Shetty, R1
Deshpande, K1
Kemmanu, V1
Kaweri, L1
Mimouni, M1
Zoller, L1
Horowitz, J1
Wygnanski-Jaffe, T1
Morad, Y1
Mezer, E1
Zhu, D1
Wang, Y1
Yang, X1
Yang, D1
Guo, K1
Guo, Y1
Jing, X1
Pan, CW1
Leydolt, C1
Neumayer, T1
Prinz, A1
Findl, O2
Rose, KA1
Ellwein, LB1
Fotouhi, A1
Iribarren, R1
Khabazkhoob, M1
Hashemi, H1
Virasch, VV1
Stwalley, D1
Kymes, SM1
Wexler, SA1
Walline, JJ1
Lindsley, K1
Vedula, SS1
Cotter, SA1
Twelker, JD1
Güell, JL1
Morral, M1
Gris, O1
Elies, D1
Manero, F1
Giessler, S1
Hammer, T1
Duncker, GI1
Hofmeister, EM1
Kaupp, SE1
Schallhorn, SC1
Jankov, MR1
Iseli, HP1
Bueeler, M1
Schor, P1
Seiler, T1
Mrochen, M1
Choong, YF1
Chen, AH1
Goh, PP1
Bujara, K1
Schulz, E1
Haase, W1
Ehrlich, DL1
Atkinson, J1
Braddick, O1
Bobier, W1
Durden, K1
Söylev, MF1
Green, RL1
Feldon, SE1
Johansen, J1
Sjølie, AK1
Eshøj, O1
Carones, F1
Brancato, R1
Morico, A1
Venturi, E1
Gobbi, PG1
Drexler, W1
Baumgartner, A1
Hitzenberger, CK1
Sattmann, H1
Fercher, AF1
Velasco Cabrera, J1
Eiroa Mozos, P1
Garcia Sanchez, J1
Bermudez Rodriguez, F1
Lin, LL1
Shih, YF1
Hsiao, CH1
Su, TC1
Chen, CJ1
Hung, PT1
Mwanza, JC1
Keech, PM1
Gartry, DS1
Muir, MG1
Lohmann, CP1
Marshall, J1
Edwards, M1
Lewis, WH1
Yen, MY1
Liu, JH1
Kao, SC1
Shiao, CH1
Hosaka, A1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Orthokeratology for High Myopia (OHM) Study[NCT03881358]66 participants (Anticipated)Interventional2018-08-04Recruiting
Myopia Progression in Children Wearing Near Center and Distance Center Multifocals - a Randomized Controlled Clinical Trial[NCT03519490]0 participants (Actual)Interventional2018-06-01Withdrawn (stopped due to Lack of interest and support)
A New More Efficient Cycloplegia Scheme[NCT02177539]Phase 430 participants (Anticipated)Interventional2014-05-31Recruiting
A Two-year, Randomized, Single-centre, Double-masked, Comparative Study to Evaluate the Annual Rate of Myopia Progression of Children With Myopia Receiving Daily BHVI1, BHVI2 Eye Drops Either Alone or in Combination[NCT04301323]Phase 1/Phase 2112 participants (Actual)Interventional2019-10-26Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for cyclopentolate and Myopia

ArticleYear
Interventions to slow progression of myopia in children.
    The Cochrane database of systematic reviews, 2011, Dec-07, Issue:12

    Topics: Atropine; Child; Contact Lenses; Cyclopentolate; Disease Progression; Eyeglasses; Humans; Muscarinic

2011
Interventions to slow progression of myopia in children.
    The Cochrane database of systematic reviews, 2011, Dec-07, Issue:12

    Topics: Atropine; Child; Contact Lenses; Cyclopentolate; Disease Progression; Eyeglasses; Humans; Muscarinic

2011
Interventions to slow progression of myopia in children.
    The Cochrane database of systematic reviews, 2011, Dec-07, Issue:12

    Topics: Atropine; Child; Contact Lenses; Cyclopentolate; Disease Progression; Eyeglasses; Humans; Muscarinic

2011
Interventions to slow progression of myopia in children.
    The Cochrane database of systematic reviews, 2011, Dec-07, Issue:12

    Topics: Atropine; Child; Contact Lenses; Cyclopentolate; Disease Progression; Eyeglasses; Humans; Muscarinic

2011

Trials

8 trials available for cyclopentolate and Myopia

ArticleYear
Efficacy of a Cycloplegic Agent Administered as a Spray in the Pediatric Population.
    Journal of pediatric ophthalmology and strabismus, 2020, Sep-01, Volume: 57, Issue:5

    Topics: Child; Child, Preschool; Cross-Sectional Studies; Cyclopentolate; Dose-Response Relationship, Drug;

2020
Effect of patient motivation on near vision in pseudophakic patients.
    American journal of ophthalmology, 2009, Volume: 147, Issue:3

    Topics: Accommodation, Ocular; Activities of Daily Living; Aged; Atropine; Ciliary Body; Cyclopentolate; Dou

2009
Comparison of tropicamide and cyclopentolate for cycloplegic refractions in myopic adult refractive surgery patients.
    Journal of cataract and refractive surgery, 2005, Volume: 31, Issue:4

    Topics: Accommodation, Ocular; Adult; Ciliary Body; Cyclopentolate; Double-Blind Method; Female; Humans; Mal

2005
Evaluation of three different approaches to perform excimer laser photorefractive keratectomy for myopia.
    Ophthalmic surgery and lasers, 1996, Volume: 27, Issue:5 Suppl

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cornea; Corneal Opacity; Cyclopentolate; Diclofenac;

1996
Changes in intraocular pressure due to cycloplegia.
    The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, Inc, 1998, Volume: 24, Issue:2

    Topics: Adolescent; Adult; Cyclopentolate; Female; Humans; Intraocular Pressure; Male; Mydriatics; Myopia; T

1998
The effect of topical corticosteroids on refractive outcome and corneal haze after photorefractive keratectomy. A prospective, randomized, double-blind trial.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1992, Volume: 110, Issue:7

    Topics: Administration, Topical; Adrenal Cortex Hormones; Adult; Aged; Chloramphenicol; Corneal Opacity; Cyc

1992
Comparison of the effect of atropine and cyclopentolate on myopia.
    Annals of ophthalmology, 1989, Volume: 21, Issue:5

    Topics: Administration, Topical; Adolescent; Atropine; Child; Cyclopentolate; Drug Evaluation; Female; Follo

1989
Myopia prevention and therapy. The role of pharmaceutical agents. Japanese studies.
    Acta ophthalmologica. Supplement, 1988, Volume: 185

    Topics: Adolescent; Child; Cyclopentolate; Humans; Labetalol; Myopia; Ophthalmic Solutions; Timolol; Tropica

1988

Other Studies

28 other studies available for cyclopentolate and Myopia

ArticleYear
[Cohort study on the association between hyperopia reserve and myopia incidence in primary school students: the Anyang Childhood Eye Study].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 2022, Oct-11, Volume: 58, Issue:10

    Topics: Child; Cohort Studies; Cornea; Cyclopentolate; Female; Humans; Hyperopia; Incidence; Male; Mydriatic

2022
Comparison of the Near Eye Tool for Refractive Assessment (NETRA) and non-cycloplegic subjective refraction.
    BMJ open ophthalmology, 2022, Volume: 7, Issue:1

    Topics: Cyclopentolate; Female; Humans; Male; Mydriatics; Myopia; Presbyopia; Refraction, Ocular; Refractive

2022
The optimal cut-off value of non-cycloplegic autorefraction for diagnosing myopia in school-aged children.
    Japanese journal of ophthalmology, 2022, Volume: 66, Issue:5

    Topics: Case-Control Studies; Child; Cyclopentolate; Humans; Male; Mydriatics; Myopia; Refraction, Ocular; R

2022
Compensation for Vitreous Chamber Elongation in Infancy and Childhood.
    Optometry and vision science : official publication of the American Academy of Optometry, 2023, 01-01, Volume: 100, Issue:1

    Topics: Adolescent; Child; Cyclopentolate; Humans; Infant; Mydriatics; Myopia; Refraction, Ocular; Refractiv

2023
Refraction under general anesthesia in children, using cycloplegic refraction only as a reference.
    Strabismus, 2020, Volume: 28, Issue:2

    Topics: Accommodation, Ocular; Anesthesia, General; Anesthetics, Combined; Child, Preschool; Cyclopentolate;

2020
Significant Axial Elongation with Minimal Change in Refraction in 3- to 6-Year-Old Chinese Preschoolers: The Shenzhen Kindergarten Eye Study.
    Ophthalmology, 2017, Volume: 124, Issue:12

    Topics: Anterior Chamber; Asian People; Axial Length, Eye; Biometry; Child; Child, Preschool; China; Cornea;

2017
Effects of the cycloplegic, cyclopentolate, on measurements of refraction in eyes of a strain of wild-type juvenile guinea pig (Cavia porcellus): a comparative study.
    Current eye research, 2014, Volume: 39, Issue:4

    Topics: Accommodation, Ocular; Animals; Cyclopentolate; Disease Models, Animal; Guinea Pigs; Mydriasis; Mydr

2014
Influence of cycloplegia with topical cyclopentolate on higher-order aberrations in myopic children.
    Eye (London, England), 2014, Volume: 28, Issue:5

    Topics: Child; Child, Preschool; Corneal Wavefront Aberration; Cyclopentolate; Female; Humans; Male; Mydriat

2014
Effects of muscarinic receptor modulators on ocular biometry of guinea pigs.
    Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 2015, Volume: 35, Issue:1

    Topics: Accommodation, Ocular; Administration, Topical; Analysis of Variance; Animals; Anterior Chamber; Cyc

2015
The Role of Aberrometry in Accommodative Spasm After Myopic Photorefractive Keratectomy.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2015, Volume: 31, Issue:12

    Topics: Aberrometry; Accommodation, Ocular; Administration, Topical; Adult; Cyclopentolate; Eye Diseases; Fe

2015
Cycloplegic autorefraction in young adults: is it mandatory?
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2016, Volume: 254, Issue:2

    Topics: Adolescent; Cyclopentolate; Female; Humans; Hyperopia; Male; Military Personnel; Mydriatics; Myopia;

2016
Pre- and Postcycloplegic Refractions in Children and Adolescents.
    PloS one, 2016, Volume: 11, Issue:12

    Topics: Adolescent; Adult; Child; China; Cyclopentolate; Female; Humans; Hyperopia; Myopia; Refraction, Ocul

2016
Is emmetropia the natural endpoint for human refractive development? An analysis of population-based data from the refractive error study in children (RESC).
    Acta ophthalmologica, 2010, Volume: 88, Issue:8

    Topics: Adolescent; Aging; Child; Child, Preschool; Cross-Sectional Studies; Cyclopentolate; Emmetropia; Eth

2010
Validity of noncycloplegic refraction in the assessment of refractive errors: the Tehran Eye Study.
    Acta ophthalmologica, 2012, Volume: 90, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Cyclopentolate; Female; Humans;

2012
Outcomes of custom laser in situ keratomileusis: dilated wavescans versus undilated wavescans.
    Journal of cataract and refractive surgery, 2011, Volume: 37, Issue:10

    Topics: Aberrometry; Adult; Cyclopentolate; Drug Therapy, Combination; Humans; Keratomileusis, Laser In Situ

2011
Transient myopic shift after phakic intraocular lens implantation.
    Journal of cataract and refractive surgery, 2012, Volume: 38, Issue:7

    Topics: Adult; Cyclopentolate; Female; Humans; Keratoconus; Lens Implantation, Intraocular; Mydriatics; Myop

2012
[Aberrometry due dilated pupils--Which mydriatic should be used?].
    Klinische Monatsblatter fur Augenheilkunde, 2002, Volume: 219, Issue:9

    Topics: Adult; Cyclopentolate; Female; Humans; Keratomileusis, Laser In Situ; Male; Mydriatics; Myopia; Opht

2002
The effect of phenylephrine and cyclopentolate on objective wavefront measurements.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2006, Volume: 22, Issue:5

    Topics: Accommodation, Ocular; Adult; Cyclopentolate; Female; Follow-Up Studies; Humans; Male; Mydriatics; M

2006
A comparison of autorefraction and subjective refraction with and without cycloplegia in primary school children.
    American journal of ophthalmology, 2006, Volume: 142, Issue:1

    Topics: Child; Cross-Sectional Studies; Cyclopentolate; Female; Humans; Hyperopia; Male; Mydriatics; Myopia;

2006
[Retinoscopy under cycloplegic and non-cycloplegic conditions in children comparison of measurements of three examiners (author's transl)].
    Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1981, Volume: 216, Issue:4

    Topics: Accommodation, Ocular; Astigmatism; Child; Cyclopentolate; Humans; Hyperopia; Mydriatics; Myopia; Op

1981
Reduction of infant myopia: a longitudinal cycloplegic study.
    Vision research, 1995, Volume: 35, Issue:9

    Topics: Aging; Astigmatism; Child, Preschool; Cyclopentolate; Humans; Infant; Longitudinal Studies; Myopia;

1995
Choroidal effusion as a mechanism for transient myopia induced by hydrochlorothiazide and triamterene.
    American journal of ophthalmology, 1995, Volume: 120, Issue:3

    Topics: Adult; Choroid Diseases; Cyclopentolate; Drug Therapy, Combination; Female; Humans; Hydrochlorothiaz

1995
Refraction and retinopathy in diabetic children below 16 years of age.
    Acta ophthalmologica, 1994, Volume: 72, Issue:6

    Topics: Adolescent; Child; Cross-Sectional Studies; Cyclopentolate; Denmark; Diabetes Mellitus, Type 1; Diab

1994
Submicrometer precision biometry of the anterior segment of the human eye.
    Investigative ophthalmology & visual science, 1997, Volume: 38, Issue:7

    Topics: Adult; Aged; Anterior Chamber; Anthropometry; Cornea; Cyclopentolate; Feasibility Studies; Female; H

1997
The cycloplegic effects of cyclopentolate and tropicamide on myopic children.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 1998, Volume: 14, Issue:4

    Topics: Accommodation, Ocular; Adolescent; Child; Ciliary Body; Cyclopentolate; Drug Combinations; Female; H

1998
Cyclopentolate and grand mal seizure.
    Bulletin de la Societe belge d'ophtalmologie, 1999, Volume: 273

    Topics: Astigmatism; Child; Cyclopentolate; Epilepsy; Epilepsy, Tonic-Clonic; Female; Humans; Myopia; Ophtha

1999
The effect of cycloplegia on the determination of refractive error by the Ophthalmetron.
    American journal of optometry and physiological optics, 1979, Volume: 56, Issue:4

    Topics: Accommodation, Ocular; Adult; Cyclopentolate; Humans; Male; Methods; Myopia; Optometry; Phenylacetat

1979
Autosomal recessive inheritance of myopia in Hong Kong Chinese infants.
    Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 1991, Volume: 11, Issue:3

    Topics: Adult; Chromosome Aberrations; Chromosome Disorders; Ciliary Body; Cyclopentolate; Female; Genes, Re

1991