Page last updated: 2024-10-25

cyclopentolate and Intraocular Pressure

cyclopentolate has been researched along with Intraocular Pressure in 30 studies

Cyclopentolate: A parasympatholytic anticholinergic used solely to obtain mydriasis or cycloplegia.
cyclopentolate : A carboxylic ester resulting from the formal condensation of (1-hydroxycyclopentyl)(phenyl)acetic acid with N,N-dimethylethanolamine. A tertiary amine antimuscarinic with actions similar to atropine, it is used as its hydrochloride salt to produce mydriasis (excessive dilation of the pupil) and cycloplegia (paralysis of the ciliary muscle of the eye) for opthalmic diagnostic procedures. It acts more quickly than atropine and has a shorter duration of action.

Intraocular Pressure: The pressure of the fluids in the eye.

Research Excerpts

ExcerptRelevanceReference
"This study was performed to investigate the effects of cyclopentolate on ultrasonographic parameters of eye structures, intraocular pressure (IOP), tear production, and pupil size in normal donkeys."8.02Effect of Topical Cyclopentolate 1% on Ocular Ultrasonographic Features, Intraocular Pressure, Tear Production, and Pupil Size in Normal Donkeys (Equus Asinus). ( Al-Lethie, AA; Elmeligy, E; Hussein, KH; Khalphallah, A, 2021)
"To determine the effects of topical 1% cyclopentolate hydrochloride on intraocular pressure (IOP), horizontal pupil diameter (HPD) and tear production in the cat and rabbit's eye during the first hour and up to 36 hours after treatment."7.96Changes in intraocular pressure, horizontal pupil diameter, and tear production during the use of topical 1% cyclopentolate in cats and rabbits. ( Kovalcuka, L; Nikolajenko, M, 2020)
"To evaluate the effect of topical cyclopentolate hydrochloride (CH) on quantitative pupillometric readings (PR), tear production (TP), and intraocular pressure (IOP) in healthy horses."7.96Effects of topical 1% cyclopentolate hydrochloride on quantitative pupillometry measurements, tear production and intraocular pressure in healthy horses. ( Armengou, L; Leiva, M; Ortillés, Á; Peña, MT; Ríos, J; Sanmartí, J, 2020)
"This study was performed to evaluate the effect of topical 1% cyclopentolate hydrochloride on tear production (STT), intraocular pressure (IOP), and vertical pupil diameter (VPD) in healthy Turkman horses."7.91Effect of Topical 1% Cyclopentolate Hydrochloride on Tear Production, Intraocular Pressure, and Pupil Size in Healthy Turkman Horses. ( Ansari Mood, M; Faghihi, H; Ghiadi, A; Rajaei, SM, 2019)
"The objective of the study was to evaluate the effect of topical 1% cyclopentolate hydrochloride (CH) on tear production (TP), pupil size (PS), and intraocular pressure (IOP) in dogs."7.83Effect of topical 1% cyclopentolate hydrochloride on tear production, pupil size, and intraocular pressure in healthy Beagles. ( Costa, D; Coyo, N; Laguna, F; Leiva, M; Peña Gimenez, MT; Ríos, J, 2016)
"To assess the effect of diagnostic mydriasis with 1% cyclopentolate on the intraocular pressure (IOP) of patients attending glaucoma, medical retina and cataract clinics."7.71Changes in intraocular pressure following diagnostic mydriasis with cyclopentolate 1%. ( Hancox, J; Murdoch, I; Parmar, D, 2002)
"The mydriasis provocative test with 1% cyclopentolate (CPT) was performed on 218 patients with suspected or untreated open-angle glaucoma, on 431 eyes in all."7.65The cyclopentolate provocative test in suspected or untreated open-angle glaucoma. I. Effect on intraocular pressure. ( Valle, O, 1976)
"The mydriasis provocative test with 1% cyclopentolate (CPT) was performed on 218 patients with suspected or untreated open-angle glaucoma, on 431 eyes in all."7.65The cyclopentolate provocative test in suspected or untreated open-angle glaucoma. II. Clinical studies on the mechanism of intraocular pressure elevations. ( Valle, O, 1976)
" responses, occurred in eyes with suspected or untreated open-angle glaucoma during the mydriasis test with 1% cyclopentolate (CPT)."7.65The cyclopentolate provocative test in suspected or untreated open-angle glaucoma. III. The significane of pigment for the result of the cyclopentolate provocative test in suspected or untreated open-angle glaucoma. ( Valle, O, 1976)
"The mydriasis provocative test with 1% cyclopentolate (CPT) was performed on 431 eyes with suspected or untreated open-angle glaucoma."7.65The cyclopentolate provocative test in suspected or untreated open-angle glaucoma. V. Statistical analysis of 431 eyes. ( Valle, O, 1976)
"We studied intraocular pressure (IOP) in a group of healthy myopic subjects before and after administration of chlorhydrate cyclopentolate 1%."5.08Changes in intraocular pressure due to cycloplegia. ( Bermudez Rodriguez, F; Eiroa Mozos, P; Garcia Sanchez, J; Velasco Cabrera, J, 1998)
"To determine the effects of topical 1% cyclopentolate hydrochloride on intraocular pressure (IOP), horizontal pupil diameter (HPD) and tear production in the cat and rabbit's eye during the first hour and up to 36 hours after treatment."3.96Changes in intraocular pressure, horizontal pupil diameter, and tear production during the use of topical 1% cyclopentolate in cats and rabbits. ( Kovalcuka, L; Nikolajenko, M, 2020)
"Corneal hysteresis (CH), corneal resistance factor (CRF), Goldmann-correlated intraocular pressure (IOPg), and corneal-compensated intraocular pressure (IOPcc) measurements of 36 (15 female and 21 male) healthy individuals, before and after 45 min of 1% cyclopentolate hydrochloride instillation, were performed by the ORA."3.80Influence of cyclopentolate hydrochloride on corneal biomechanical properties in healthy individuals. ( Kerimoğlu, H; Okka, M; Oltulu, R; Ozkağnici, A; Satirtav, G; Zengin, N, 2014)
"To assess the effect of diagnostic mydriasis with 1% cyclopentolate on the intraocular pressure (IOP) of patients attending glaucoma, medical retina and cataract clinics."3.71Changes in intraocular pressure following diagnostic mydriasis with cyclopentolate 1%. ( Hancox, J; Murdoch, I; Parmar, D, 2002)
" responses, occurred in eyes with suspected or untreated open-angle glaucoma during the mydriasis test with 1% cyclopentolate (CPT)."3.65The cyclopentolate provocative test in suspected or untreated open-angle glaucoma. III. The significane of pigment for the result of the cyclopentolate provocative test in suspected or untreated open-angle glaucoma. ( Valle, O, 1976)
"The mydriasis provocative test with 1% cyclopentolate (CPT) was performed on 431 eyes with suspected or untreated open-angle glaucoma."3.65The cyclopentolate provocative test in suspected or untreated open-angle glaucoma. V. Statistical analysis of 431 eyes. ( Valle, O, 1976)
" Since long-term use of corticosteroids to maintain the initial beneficial effect on refraction would be unacceptable, we conclude that these agents should not be used after photorefractive keratectomy."2.67The effect of topical corticosteroids on refractive outcome and corneal haze after photorefractive keratectomy. A prospective, randomized, double-blind trial. ( Gartry, DS; Lohmann, CP; Marshall, J; Muir, MG, 1992)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19907 (23.33)18.7374
1990's4 (13.33)18.2507
2000's7 (23.33)29.6817
2010's8 (26.67)24.3611
2020's4 (13.33)2.80

Authors

AuthorsStudies
Kovalcuka, L1
Nikolajenko, M1
Edwards, RG1
Vanderhoof, S1
Palestine, A1
Seibold, LK1
Ortillés, Á1
Sanmartí, J1
Ríos, J2
Armengou, L1
Peña, MT1
Leiva, M2
Hussein, KH1
Elmeligy, E1
Khalphallah, A1
Al-Lethie, AA1
Ansari Mood, M1
Rajaei, SM1
Faghihi, H1
Ghiadi, A1
Tsui, E1
Sehi, M1
Cheng, RW1
Wan, J1
Wong, T1
Dorner, S1
Fisher, JA1
Hudson, C1
Oltulu, R1
Satirtav, G1
Kerimoğlu, H1
Zengin, N1
Ozkağnici, A1
Okka, M1
Costa, D1
Coyo, N1
Laguna, F1
Peña Gimenez, MT1
Rosman, MS1
Skaat, A1
Chien, JL1
Ghassibi, MP1
Sarimiye, TF1
Ritch, R1
Liebmann, JM1
Park, SC1
Mocan, MC1
Bozkurt, B1
Irkec, M1
Orhan, M1
Li Yim, JF1
Ross, JZ1
Jay, JL1
Lundberg, B2
Behndig, A2
Koktekir, BE1
Gedik, S1
Bakbak, B1
Hancox, J1
Murdoch, I1
Parmar, D1
Sommer, A1
Stark, WJ1
Mittal, A1
Mittal, S1
Bharathi, JM1
Ramakrishnan, R1
Sathe, PS1
Low, S1
Harsum, S1
Chang, L1
Foster, PJ1
Khaw, PT1
Aminlari, A1
Sassani, JW1
Mishima, HK1
Shoge, K1
Takamatsu, M1
Kiuchi, Y1
Tanaka, J1
Velasco Cabrera, J1
Eiroa Mozos, P1
Garcia Sanchez, J1
Bermudez Rodriguez, F1
Caprioli, J1
Samson, CM1
Foster, CS1
Araie, M1
Rockwood, EJ1
Bleiman, BS1
Schwartz, AL1
Pecora, JL1
Kopel, J1
Valle, O4
Gartry, DS1
Muir, MG1
Lohmann, CP1
Marshall, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized, Controlled, Double-Masked, Multicenter, Exploratory Study of the Clinical Benefit and Safety of OMS302 Injection in Subjects Undergoing Unilateral Cataract Extraction With Lens Replacement (CELR) Using a Coaxial Phacoemulsification Process[NCT00721695]Phase 1/Phase 260 participants (Actual)Interventional2008-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for cyclopentolate and Intraocular Pressure

ArticleYear
Bilateral Secondary Angle Closure During Daratumumab Infusion: A Case Report and Review of the Literature.
    Journal of glaucoma, 2020, Volume: 29, Issue:8

    Topics: Administration, Ophthalmic; Amyloidosis; Antibodies, Monoclonal; Antineoplastic Agents; Choroidal Ef

2020

Trials

4 trials available for cyclopentolate and Intraocular Pressure

ArticleYear
Intracameral mydriatics in phacoemulsification cataract surgery -- a 6-year follow-up.
    Acta ophthalmologica, 2013, Volume: 91, Issue:3

    Topics: Administration, Topical; Aged; Anterior Chamber; Capsule Opacification; Cornea; Corneal Endothelial

2013
Intracameral mydriatics in phacoemulsification cataract surgery.
    Journal of cataract and refractive surgery, 2003, Volume: 29, Issue:12

    Topics: Administration, Topical; Aged; Anterior Chamber; Blood Pressure; Cell Count; Cyclopentolate; Double-

2003
Changes in intraocular pressure due to cycloplegia.
    The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, Inc, 1998, Volume: 24, Issue:2

    Topics: Adolescent; Adult; Cyclopentolate; Female; Humans; Intraocular Pressure; Male; Mydriatics; Myopia; T

1998
The effect of topical corticosteroids on refractive outcome and corneal haze after photorefractive keratectomy. A prospective, randomized, double-blind trial.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1992, Volume: 110, Issue:7

    Topics: Administration, Topical; Adrenal Cortex Hormones; Adult; Aged; Chloramphenicol; Corneal Opacity; Cyc

1992

Other Studies

25 other studies available for cyclopentolate and Intraocular Pressure

ArticleYear
Changes in intraocular pressure, horizontal pupil diameter, and tear production during the use of topical 1% cyclopentolate in cats and rabbits.
    Open veterinary journal, 2020, Volume: 10, Issue:1

    Topics: Animals; Cat Diseases; Cats; Cyclopentolate; Intraocular Pressure; Lacrimal Apparatus Diseases; Mydr

2020
Effects of topical 1% cyclopentolate hydrochloride on quantitative pupillometry measurements, tear production and intraocular pressure in healthy horses.
    Veterinary ophthalmology, 2020, Volume: 23, Issue:4

    Topics: Animals; Cyclopentolate; Female; Horses; Intraocular Pressure; Male; Mydriatics; Ophthalmic Solution

2020
Effect of Topical Cyclopentolate 1% on Ocular Ultrasonographic Features, Intraocular Pressure, Tear Production, and Pupil Size in Normal Donkeys (Equus Asinus).
    Journal of equine veterinary science, 2021, Volume: 104

    Topics: Animals; Cyclopentolate; Equidae; Intraocular Pressure; Pupil; Tonometry, Ocular

2021
Effect of Topical 1% Cyclopentolate Hydrochloride on Tear Production, Intraocular Pressure, and Pupil Size in Healthy Turkman Horses.
    Journal of equine veterinary science, 2019, Volume: 75

    Topics: Animals; Cyclopentolate; Horses; Intraocular Pressure; Mydriatics; Pupil; Tonometry, Ocular

2019
The impact of topical mydriatic ophthalmic solutions on retinal vascular reactivity and blood flow.
    Experimental eye research, 2013, Volume: 112

    Topics: Administration, Topical; Arterioles; Blood Flow Velocity; Blood Pressure; Cyclopentolate; Drug Combi

2013
Influence of cyclopentolate hydrochloride on corneal biomechanical properties in healthy individuals.
    Eye & contact lens, 2014, Volume: 40, Issue:5

    Topics: Adolescent; Adult; Biomechanical Phenomena; Cornea; Cyclopentolate; Female; Humans; Intraocular Pres

2014
Effect of topical 1% cyclopentolate hydrochloride on tear production, pupil size, and intraocular pressure in healthy Beagles.
    Veterinary ophthalmology, 2016, Volume: 19, Issue:6

    Topics: Animals; Cyclopentolate; Dogs; Intraocular Pressure; Mydriatics; Pupil; Random Allocation; Tears; To

2016
Effect of Cyclopentolate on In Vivo Schlemm Canal Microarchitecture in Healthy Subjects.
    Journal of glaucoma, 2017, Volume: 26, Issue:2

    Topics: Adult; Cyclopentolate; Female; Healthy Volunteers; Humans; Intraocular Pressure; Limbus Corneae; Mal

2017
Urrets-Zavalia syndrome following iatrogenic pupil dilation in eyes with pigment dispersion.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2009, Volume: 44, Issue:2

    Topics: Adult; Anterior Chamber; Atrophy; Cyclopentolate; Dexamethasone; Exfoliation Syndrome; Female; Glauc

2009
Pupil block following inadvertent back to front implantation of a 5 degrees vaulted posterior chamber intraocular lens.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2010, Volume: 45, Issue:3

    Topics: Acetazolamide; Aged; Cyclopentolate; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocula

2010
Bilateral severe anterior uveitis after unilateral selective laser trabeculoplasty.
    Clinical & experimental ophthalmology, 2013, Volume: 41, Issue:3

    Topics: Adult; Anterior Chamber; Cyclopentolate; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Gl

2013
Changes in intraocular pressure following diagnostic mydriasis with cyclopentolate 1%.
    Eye (London, England), 2002, Volume: 16, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Cataract; Cyclopentolate; Female; Glaucoma; Humans; Intraocular Pres

2002
Through a yellow glass darkly.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2007, Volume: 125, Issue:5

    Topics: Acetylcholine; Cataract Extraction; Cholinergic Agents; Cyclopentolate; Humans; Intraocular Pressure

2007
Uveitis during outbreak of Chikungunya fever.
    Ophthalmology, 2007, Volume: 114, Issue:9

    Topics: Adult; Aged; Alphavirus Infections; Antihypertensive Agents; Chikungunya virus; Cyclopentolate; Dise

2007
Angle-closure.
    Ophthalmology, 2008, Volume: 115, Issue:8

    Topics: Acute Disease; Anterior Eye Segment; Antihypertensive Agents; Child, Preschool; Cyclopentolate; Drug

2008
Simultaneous bilateral malignant glaucoma following laser iridotomy.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1993, Volume: 231, Issue:1

    Topics: Atropine; Cyclopentolate; Female; Glaucoma, Angle-Closure; Humans; Hydrochlorothiazide; Intraocular

1993
Ultrasound biomicroscopic study of ciliary body thickness after topical application of pharmacologic agents.
    American journal of ophthalmology, 1996, Volume: 121, Issue:3

    Topics: Administration, Topical; Adult; Anthropometry; Ciliary Body; Cyclopentolate; Double-Blind Method; Hu

1996
Uveitis and glaucoma.
    Journal of glaucoma, 2000, Volume: 9, Issue:6

    Topics: Antihypertensive Agents; Cataract; Cataract Extraction; Cyclopentolate; Drug Therapy, Combination; F

2000
Paradoxical intraocular pressure response to pilocarpine. A proposed mechanism and treatment.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1979, Volume: 97, Issue:7

    Topics: Atropine; Cyclopentolate; Echothiophate Iodide; Glaucoma; Humans; Intraocular Pressure; Male; Middle

1979
Malignant glaucoma worsened by miotics in a postoperative angle-closure glaucoma patient.
    Annals of ophthalmology, 1979, Volume: 11, Issue:9

    Topics: Acetazolamide; Atropine; Cyclopentolate; Female; Glaucoma; Humans; Intraocular Pressure; Middle Aged

1979
[Provocation tests in closed-angle glaucoma].
    Bulletin des societes d'ophtalmologie de France, 1978, Volume: 78, Issue:2

    Topics: Accommodation, Ocular; Cyclopentolate; Glaucoma; Humans; Intraocular Pressure; Methods; Phenylephrin

1978
The cyclopentolate provocative test in suspected or untreated open-angle glaucoma. I. Effect on intraocular pressure.
    Acta ophthalmologica, 1976, Volume: 54, Issue:4

    Topics: Adult; Aged; Circadian Rhythm; Cyclopentolate; Female; Glaucoma; Humans; Intraocular Pressure; Male;

1976
The cyclopentolate provocative test in suspected or untreated open-angle glaucoma. II. Clinical studies on the mechanism of intraocular pressure elevations.
    Acta ophthalmologica, 1976, Volume: 54, Issue:4

    Topics: Adult; Aged; Cyclopentolate; Female; Glaucoma; Humans; Intraocular Pressure; Lens, Crystalline; Male

1976
The cyclopentolate provocative test in suspected or untreated open-angle glaucoma. III. The significane of pigment for the result of the cyclopentolate provocative test in suspected or untreated open-angle glaucoma.
    Acta ophthalmologica, 1976, Volume: 54, Issue:5

    Topics: Aqueous Humor; Cyclopentolate; Glaucoma; Humans; Intraocular Pressure; Lens, Crystalline; Phenylacet

1976
The cyclopentolate provocative test in suspected or untreated open-angle glaucoma. V. Statistical analysis of 431 eyes.
    Acta ophthalmologica, 1976, Volume: 54, Issue:6

    Topics: Aqueous Humor; Cyclopentolate; Glaucoma; Humans; Intraocular Pressure; Phenylacetates; Statistics as

1976