Page last updated: 2024-10-25

cyclopentolate and Eye Disorders

cyclopentolate has been researched along with Eye Disorders in 12 studies

Cyclopentolate: A parasympatholytic anticholinergic used solely to obtain mydriasis or cycloplegia.
cyclopentolate : A carboxylic ester resulting from the formal condensation of (1-hydroxycyclopentyl)(phenyl)acetic acid with N,N-dimethylethanolamine. A tertiary amine antimuscarinic with actions similar to atropine, it is used as its hydrochloride salt to produce mydriasis (excessive dilation of the pupil) and cycloplegia (paralysis of the ciliary muscle of the eye) for opthalmic diagnostic procedures. It acts more quickly than atropine and has a shorter duration of action.

Research Excerpts

ExcerptRelevanceReference
"Cyclopentolate has been widely used as a cycloplegic and mydriatic agent for over 30 years."2.38Possible allergic reactions to cyclopentolate hydrochloride: case reports with literature review of uses and adverse reactions. ( Hodes, DT; Jones, LW, 1991)
" Adverse effects are often related to dosage or other factors."2.36Mydriatic and cycloplegic drugs: a review of ocular and systemic complications. ( Doughty, CB; Rengstorff, RH, 1982)
" The ocular drugs causing serious adverse ocular or systemic side effects in children include glaucoma medications, corticosteroids, phenylephrine, and the anticholinergic cycloplegics."1.27How safe are ocular drugs in pediatrics? ( Palmer, EA, 1986)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19906 (50.00)18.7374
1990's2 (16.67)18.2507
2000's2 (16.67)29.6817
2010's1 (8.33)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Edwards, RG1
Vanderhoof, S1
Palestine, A1
Seibold, LK1
Shetty, R1
Deshpande, K1
Kemmanu, V1
Kaweri, L1
BARKMAN, Y1
Hug, T1
Olitsky, S1
Cowan, EC1
Archer, D1
Rengstorff, RH1
Doughty, CB1
Barry, JC1
Loewen, N1
Davidson, S1
Awan, KJ1
Jones, LW1
Hodes, DT1
Palmer, EA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A New More Efficient Cycloplegia Scheme[NCT02177539]Phase 430 participants (Anticipated)Interventional2014-05-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for cyclopentolate and Eye Disorders

ArticleYear
Bilateral Secondary Angle Closure During Daratumumab Infusion: A Case Report and Review of the Literature.
    Journal of glaucoma, 2020, Volume: 29, Issue:8

    Topics: Administration, Ophthalmic; Amyloidosis; Antibodies, Monoclonal; Antineoplastic Agents; Choroidal Ef

2020
Mydriatic and cycloplegic drugs: a review of ocular and systemic complications.
    American journal of optometry and physiological optics, 1982, Volume: 59, Issue:2

    Topics: Adolescent; Adult; Aged; Atropine; Autonomic Nervous System Diseases; Child; Child, Preschool; Cyclo

1982
Possible allergic reactions to cyclopentolate hydrochloride: case reports with literature review of uses and adverse reactions.
    Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 1991, Volume: 11, Issue:1

    Topics: Child; Child, Preschool; Ciliary Body; Cyclopentolate; Drug Hypersensitivity; Eye Diseases; Female;

1991

Trials

1 trial available for cyclopentolate and Eye Disorders

ArticleYear
CLINICAL EVALUATION OF A NEW MYDRIATIC-MYDRILATE.
    The British journal of ophthalmology, 1962, Volume: 46, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Atropine; Cyclopentolate; Eye Color; Eye Diseases; Femal

1962

Other Studies

8 other studies available for cyclopentolate and Eye Disorders

ArticleYear
The Role of Aberrometry in Accommodative Spasm After Myopic Photorefractive Keratectomy.
    Journal of refractive surgery (Thorofare, N.J. : 1995), 2015, Volume: 31, Issue:12

    Topics: Aberrometry; Accommodation, Ocular; Administration, Topical; Adult; Cyclopentolate; Eye Diseases; Fe

2015
[Cyclogyl, a new mydriatic & ganglion blocking drug for diagnostic use].
    Svenska lakartidningen, 1958, May-02, Volume: 55, Issue:18

    Topics: Autonomic Agents; Cyclopentolate; Diagnostic Techniques, Ophthalmological; Eye Diseases; Ganglionic

1958
Dilation efficacy: is 1% cyclopentolate enough?
    Optometry (St. Louis, Mo.), 2007, Volume: 78, Issue:3

    Topics: Anesthetics, Local; Child; Child, Preschool; Cyclopentolate; Dose-Response Relationship, Drug; Eye C

2007
A 23-year-old maintenance employee in a fertilizer manufacturing plant was exposed to a high concentration of ammonia vapor after a pipe ruptured.
    Journal of occupational and environmental medicine, 1995, Volume: 37, Issue:10

    Topics: Accidents, Occupational; Adult; Ammonia; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroi

1995
[Experiences with cycloplegic drops in German-speaking centers of pediatric ophthalmology and stabology--results of a 1999 survey].
    Klinische Monatsblatter fur Augenheilkunde, 2001, Volume: 218, Issue:1

    Topics: Adverse Drug Reaction Reporting Systems; Atropine; Child; Child, Preschool; Cyclopentolate; Eye Dise

2001
General medicine and visual side effects.
    British medical journal, 1979, Mar-24, Volume: 1, Issue:6166

    Topics: Cataract; Chloroquine; Cyclopentolate; Eye Diseases; Glaucoma; Humans; Prednisone

1979
Adverse systemic reactions of topical cyclopentolate hydrochloride.
    Annals of ophthalmology, 1976, Volume: 8, Issue:6

    Topics: Administration, Topical; Adolescent; Adult; Cyclopentolate; Eye Diseases; Female; Humans; Male; Phen

1976
How safe are ocular drugs in pediatrics?
    Ophthalmology, 1986, Volume: 93, Issue:8

    Topics: Absorption; Atropine; Child; Child, Preschool; Cholinesterase Inhibitors; Cyclopentolate; Echothioph

1986