Page last updated: 2024-08-21

cyclopentane and Neoplasms

cyclopentane has been researched along with Neoplasms in 65 studies

Research

Studies (65)

Timeframe	Studies, this research(%)	All Research%
pre-1990	8 (12.31)	18.7374
1990's	2 (3.08)	18.2507
2000's	14 (21.54)	29.6817
2010's	31 (47.69)	24.3611
2020's	10 (15.38)	2.80

Authors

Authors	Studies
Chen, Q; Dou, L; Li, H; Meredith, MA; Sun, Y; Xiong, X; Xu, T; You, X; Zhang, S	1
Aladjem, MI; Ceribelli, M; Fu, H; Jo, U; Murai, J; Murai, Y; Pommier, Y; Redon, CE; Thomas, CJ	1
Guo, ZS	1
Fokin, AI; Onishchenko, GE; Potashnikova, DM; Saidova, AA; Smirnova, EA; Vildanova, MS	1
Sun, Y; Zhang, S	1
Jia, L; Zhou, L	1
Chen, ZS; Fan, YF; Li, JS; Ma, XY; Wei, LY; Wu, ZX; Yang, DH; Yang, Y; Zhao, M	1
He, S; Rao, F; Shi, S; Su, Y; Wu, J; Yang, X; Zhang, J; Zhang, X	1
Bömer, M; Cinar, A; Devoto, A; Dudenhoffer, JH; Finch, P; Florance, HV; Harvey, A; Pérez-Salamó, I; Salmon, D; Smirnoff, N	1
Kroonen, JS; Vertegaal, ACO	1
Jarocka-Karpowicz, I; Markowska, A	1
Jia, L; Sun, Y; Zhang, W; Zhou, L	1
Chun, YS; Kim, SJ; Lee, GW; Park, JB; Park, JW; Park, SY; Seo, J; Shin, SH; Watanabe, M	1
Cui, C; Fu, L; Ge, C; Song, X; Su, X; To, KKW; Wang, F; Wang, X; Zhang, H	1
Fujii, T; Fujita, K; Funayama, K; Ikari, A; Sakai, H; Shimizu, T; Tabuchi, Y; Takeshima, H; Yamamoto, S	1
Cao, C; Fan, S; Guan, MX; Jin, H; Li, H; Li, Y; Meng, F; Sun, Y; Tan, M; Zhao, L; Zhou, Q; Zhu, L	1
Bauer, TM; Faessel, H; Faller, DV; Harvey, RD; Lockhart, AC; Nemunaitis, J; Sedarati, F; Venkatakrishnan, K; Zhou, X	1
Hu, Q; Liu, M; Liu, Y; Shang, Q; Xue, Y; Yin, L; Zhu, H	1
Jia, L; Jiang, Y; Li, L; Luo, Q; Zhou, L	1
Ehrenschwender, M; Heimer, S; Knoll, G; Schulze-Osthoff, K	1
Guzel, M; Ipek, OS; Karakas, N; Kurtulus, SO; Sucu, BO; Yazici, BE	1
Alam, MM; Joh, EH; Kim, B; Kim, DH; Lee, YS; Park, H	1
Avecilla, F; Garcia, MH; Gonçalves, AC; Marques, F; Matos, CP; Morais, TS; Robalo, MP; Santos, I; Tomaz, AI	1
Patil, SP	1
Berger, A; Blakemore, SJ; Bowman, D; Burke, KE; Chakravarty, A; Ecsedy, J; Fleming, M; McDonald, AA; Shinde, V; Tirrell, SM	1
Jia, L; Jiang, Y	1
Zhang, L; Zhang, M; Zhang, MW	1
Baradaran, B; Islamian, JP; Monfared, AS; Oladghaffari, M	1
Berger, AJ; Burke, K; Clark, JW; Cleary, JM; Cohen, RB; Dezube, BJ; Faessel, HM; Harvey, RD; Kauh, JS; Mahalingam, D; Mulligan, G; Pickard, MD; Sarantopoulos, J; Shapiro, GI; Weiss, GJ	1
Garcia, MH; Marques, F; Morais, TS; Tomaz, AI; Valente, A	1
Dewit, MA; Luyt, LG; Rosita, D	1
Adhikari, S; Berger, AJ; Bolen, JB; Brownell, JE; Burke, KE; Cardin, DP; Claiborne, CF; Critchley, S; Cullis, CA; Dick, LR; Doucette, A; Garnsey, JJ; Gaulin, JL; Gavin, JM; Gershman, RE; Langston, SP; Lublinsky, AR; McDonald, A; Milhollen, MA; Mizutani, H; Narayanan, U; Olhava, EJ; Peluso, S; Rezaei, M; Rolfe, M; Sintchak, MD; Smith, PG; Soucy, TA; Talreja, T; Thomas, MP; Traore, T; Vyskocil, S; Weatherhead, GS; Yu, J; Zhang, J	1
Rolfe, M; Smith, PG; Soucy, TA	1
Cohen, S; Flescher, E	1
Chen, ZJ; Skaug, B	1
Chen, CJ; Chen, HJ; Gao, K; Liu, Q; Shi, X; Zhang, L	1
Li, J; Wu, X; Zhang, D	1
Camp, D; Campitelli, M; Hegde, V; Quinn, RJ	1
Chan, CH; Gao, Y; Lin, HK; Wang, G	1
Elia, U; Flescher, E	1
Kamitani, T; Nakatani, T; Tanaka, T	2
Carew, JS; Griffin, P; Kelly, KR; Nawrocki, ST	1
Jeong, LS; Jia, L; Liu, J; Luo, Z; Pan, Y	1
Cohen, S; Raviv, Z; Reischer-Pelech, D	1
Frank, O; Habermeyer, M; Hofmann, T; Kemény, M; Marko, D; Niederberger, E; Weyand, U	1
BARTON, H; GRAFFI, A; JUNG, F; KRISCHKE, W	1
AKASHI, A; HANO, K; IWATA, H	1
BRUNORI, M; CAPUTO, A; GIULIANO, R	2
ASHIZAWA, A	1
DICKENS, F; JONES, HE	1
Flescher, E	2
Flescher, E; Goldin, N; Heyfets, A; Reischer, D	1
Claffey, J; Hogan, M; Pampillón, C; Tacke, M	1
Arzoine, L; Bravman, T; Bronner, V; Flescher, E; Goldin, N; Heyfets, A; Israelson, A; Notcovich, A; Shoshan-Barmatz, V; Zaslavsky, Z	1
Galluzzi, L; Kepp, O; Kroemer, G; Tajeddine, N	1
Kikuchi, K; Sato, N; Tamura, Y; Tsuboi, N	1
Lupulescu, A	1
Curi, R; Homem de Bittencourt, PI	1
Ebine, T; Fukui, T; Kawai, KI; Maitani, Y; Shimizu, K; Takahashi, N; Tamagawa, K	1
Bernady, E; Frank, O; Habermeyer, M; Hofmann, T; Kemény, M; Marko, D; Meiers, S; Weyand, U	1
Agranat, I; Cascieri, T; Chase, AR; Cox, CH; Hernandez, RE; Kimball, ES; Soloway, AH	1
Andrews, NC; Aust, JB; Lawton, RL; Schroeder, JM	1

Reviews

21 review(s) available for cyclopentane and Neoplasms

Article	Year
Targeting Protein Neddylation for Cancer Therapy. Advances in experimental medicine and biology, 2020, Volume: 1217 Topics: Animals; Apoptosis; Autophagy; Cyclopentanes; Humans; NEDD8 Protein; Neoplasms; Pyrimidines; Ubiquitin-Protein Ligases; Ubiquitination	2020
Targeting SUMO Signaling to Wrestle Cancer. Trends in cancer, 2021, Volume: 7, Issue:6 Topics: Antineoplastic Agents; Cell Cycle; Cell Proliferation; Clinical Trials as Topic; Cyclopentanes; Gene Expression Regulation, Neoplastic; Humans; NEDD8 Protein; Neoplasms; Pyrazoles; Pyrimidines; Signal Transduction; Small Ubiquitin-Related Modifier Proteins; Sulfides; Sulfonamides; Sumoylation; Ubiquitin-Activating Enzymes	2021
Therapeutic Potential of Jasmonic Acid and Its Derivatives. International journal of molecular sciences, 2021, Aug-05, Volume: 22, Issue:16 Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Cyclopentanes; Humans; Neoplasms; Oxylipins; Plants	2021
Protein neddylation and its alterations in human cancers for targeted therapy. Cellular signalling, 2018, Volume: 44 Topics: Apoptosis; Autophagy; Cell Cycle Checkpoints; Cellular Senescence; Cyclopentanes; Humans; Molecular Targeted Therapy; Neoplasms; Protein Processing, Post-Translational; Pyrimidines; Ubiquitin-Activating Enzymes; Ubiquitin-Protein Ligases	2018
Pharmaceutical Inhibition of Neddylation as Promising Treatments for Various Cancers. Current topics in medicinal chemistry, 2019, Volume: 19, Issue:12 Topics: Antineoplastic Agents; Biological Products; Cyclopentanes; Epigenesis, Genetic; Humans; NEDD8 Protein; Neoplasms; Protein Processing, Post-Translational; Pyrimidines	2019
Neddylation: a novel modulator of the tumor microenvironment. Molecular cancer, 2019, 04-03, Volume: 18, Issue:1 Topics: Cancer-Associated Fibroblasts; Cell Survival; Cellular Senescence; Clinical Trials as Topic; Cyclopentanes; Humans; NEDD8 Protein; Neoplasms; Pyrimidines; Signal Transduction; Tumor Microenvironment	2019
Neddylation Pathway as a Novel Anti-cancer Target: Mechanistic Investigation and Therapeutic Implication. Anti-cancer agents in medicinal chemistry, 2015, Volume: 15, Issue:9 Topics: Antineoplastic Agents; Cyclopentanes; Humans; Macrophages; NEDD8 Protein; Neoplasms; Neovascularization, Pathologic; Pyrimidines; Ubiquitins	2015
MLN4924 therapy as a novel approach in cancer treatment modalities. Journal of chemotherapy (Florence, Italy), 2016, Volume: 28, Issue:2 Topics: Antineoplastic Agents; Apoptosis; Autophagy; Cell Cycle Proteins; Cullin Proteins; Cyclopentanes; Humans; Neoplasms; NF-KappaB Inhibitor alpha; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; Radiation-Sensitizing Agents	2016
Tracking antitumor metallodrugs: promising agents with the Ru(II)- and Fe(II)-cyclopentadienyl scaffolds. Future medicinal chemistry, 2016, Volume: 8, Issue:5 Topics: Antineoplastic Agents; Cell Line, Tumor; Coordination Complexes; Cyclopentanes; Dimethyl Sulfoxide; Drug Discovery; Ferrous Compounds; Humans; Indazoles; Molecular Targeted Therapy; Neoplasms; Organometallic Compounds; Protein Binding; Ruthenium; Ruthenium Compounds	2016
Methyl jasmonate: a plant stress hormone as an anti-cancer drug. Phytochemistry, 2009, Volume: 70, Issue:13-14 Topics: Acetates; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cyclopentanes; Humans; Models, Biological; Neoplasms; Oxylipins; Plant Growth Regulators	2009
Novel roles of Skp2 E3 ligase in cellular senescence, cancer progression, and metastasis. Chinese journal of cancer, 2012, Volume: 31, Issue:4 Topics: Animals; Cell Movement; Cellular Senescence; Cyclopentanes; Disease Progression; Drug Delivery Systems; Gene Expression Regulation, Neoplastic; Humans; Neoplasms; Pyrimidines; S-Phase Kinase-Associated Proteins; Ubiquitination	2012
Combined chemotherapy or biotherapy with jasmonates: targeting energy metabolism for cancer treatment. Current pharmaceutical biotechnology, 2013, Volume: 14, Issue:3 Topics: Acetates; Animals; Antineoplastic Agents; Cyclopentanes; Drug Combinations; Humans; Mitochondria; Neoplasms; Oxylipins	2013
Inhibition of NEDD8-conjugation pathway by novel molecules: potential approaches to anticancer therapy. Molecular oncology, 2012, Volume: 6, Issue:3 Topics: Animals; Cyclopentanes; Humans; NEDD8 Protein; Neoplasms; Pyrimidines; Signal Transduction; SKP Cullin F-Box Protein Ligases; Ubiquitins	2012
MLN4924: a novel first-in-class inhibitor of NEDD8-activating enzyme for cancer therapy. Expert opinion on investigational drugs, 2012, Volume: 21, Issue:10 Topics: Animals; Antineoplastic Agents; Cyclopentanes; Humans; NEDD8 Protein; Neoplasms; Pyrimidines; Ubiquitins	2012
Negative regulation of NEDD8 conjugation pathway by novel molecules and agents for anticancer therapy. Current pharmaceutical design, 2013, Volume: 19, Issue:22 Topics: Antineoplastic Agents; Cyclopentanes; Humans; NEDD8 Protein; Neoplasms; Proteasome Endopeptidase Complex; Pyrimidines; Ubiquitins	2013
The anti-cancer activities of jasmonates. Cancer chemotherapy and pharmacology, 2013, Volume: 71, Issue:2 Topics: Acetates; Animals; Antineoplastic Agents; Apoptosis; Cyclopentanes; Gene Expression Regulation, Neoplastic; Humans; Neoplasms; Oxylipins; Plant Growth Regulators; Reactive Oxygen Species; TNF-Related Apoptosis-Inducing Ligand	2013
Jasmonates--a new family of anti-cancer agents. Anti-cancer drugs, 2005, Volume: 16, Issue:9 Topics: Acetates; Animals; Antineoplastic Agents; Cell Proliferation; Cell Survival; Cyclopentanes; Humans; Mitochondria; Molecular Structure; Neoplasms; Oxylipins; Plant Growth Regulators	2005
Jasmonates in cancer therapy. Cancer letters, 2007, Jan-08, Volume: 245, Issue:1-2 Topics: Animals; Apoptosis; Cell Line, Tumor; Cyclopentanes; Humans; Mitogen-Activated Protein Kinases; Models, Biological; Neoplasms; Oxylipins; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species	2007
Mitochondria-mediated ATP depletion by anti-cancer agents of the jasmonate family. Journal of bioenergetics and biomembranes, 2007, Volume: 39, Issue:1 Topics: Adenosine Triphosphate; Antineoplastic Agents, Phytogenic; Cyclopentanes; Energy Metabolism; Humans; Mitochondria; Neoplasms; Oxidative Phosphorylation; Oxylipins; Tumor Suppressor Protein p53	2007
Prostaglandins, their inhibitors and cancer. Prostaglandins, leukotrienes, and essential fatty acids, 1996, Volume: 54, Issue:2 Topics: Adjuvants, Immunologic; Anti-Inflammatory Agents, Non-Steroidal; Cyclopentanes; Disease Progression; Humans; Neoplasm Transplantation; Neoplasms; Prostaglandin Antagonists; Prostaglandins	1996
Antiproliferative prostaglandins and the MRP/GS-X pump role in cancer immunosuppression and insight into new strategies in cancer gene therapy. Biochemical pharmacology, 2001, Oct-01, Volume: 62, Issue:7 Topics: Animals; Carrier Proteins; Cyclopentanes; Drug Resistance, Multiple; Genetic Therapy; Humans; Immunosuppression Therapy; Membrane Transport Proteins; Neoplasms; Prostaglandins	2001

Trials

3 trial(s) available for cyclopentane and Neoplasms

Article	Year
Effect of CYP3A inhibitors on the pharmacokinetics of pevonedistat in patients with advanced solid tumours. British journal of clinical pharmacology, 2019, Volume: 85, Issue:7 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carboplatin; Cyclopentanes; Cytochrome P-450 CYP3A Inhibitors; Docetaxel; Drug Interactions; Enzyme Inhibitors; Female; Fluconazole; Humans; Itraconazole; Male; Middle Aged; Neoplasms; Paclitaxel; Pyrimidines	2019
Phase I Study of the Investigational NEDD8-Activating Enzyme Inhibitor Pevonedistat (TAK-924/MLN4924) in Patients with Advanced Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research, 2016, Feb-15, Volume: 22, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Cyclopentanes; Female; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Pyrimidines; Treatment Outcome; Tumor Burden; Ubiquitin-Activating Enzymes	2016
Clinical note. Phase II study of 1-aminocyclopentanecarboxylic acid (NSC-1026) in patients with cancer. Cancer chemotherapy reports, 1970, Volume: 54, Issue:4 Topics: Amino Acids; Clinical Trials as Topic; Colonic Neoplasms; Cyclopentanes; Evaluation Studies as Topic; Feeding and Eating Disorders; Head and Neck Neoplasms; Humans; Leiomyosarcoma; Male; Neoplasms; Rectal Neoplasms; Sarcoma; Testicular Neoplasms; Valine; Vomiting	1970

Other Studies

41 other study(ies) available for cyclopentane and Neoplasms

Article	Year
PD-L1 induction via the MEK-JNK-AP1 axis by a neddylation inhibitor promotes cancer-associated immunosuppression. Cell death & disease, 2022, 10-03, Volume: 13, Issue:10 Topics: Animals; Apoptosis; Cell Line, Tumor; Cyclopentanes; Humans; Immunosuppression Therapy; Mice; Mitogen-Activated Protein Kinase Kinases; NEDD8 Protein; Neoplasms; Protein Kinase Inhibitors; Pyrimidines; RNA, Messenger; Transcription Factor AP-1	2022
Schlafen 11 (SLFN11) Kills Cancer Cells Undergoing Unscheduled Re-replication. Molecular cancer therapeutics, 2023, 08-01, Volume: 22, Issue:8 Topics: Antineoplastic Agents; Cell Line, Tumor; Chromatin; Cyclopentanes; Humans; Neoplasms; Nuclear Proteins	2023
Oncolytic virus and inhibitor for NEDD8-activating enzyme pevonedistat: Promising combination for cancer therapy? Molecular therapy : the journal of the American Society of Gene Therapy, 2023, 11-01, Volume: 31, Issue:11 Topics: Antineoplastic Agents; Cyclopentanes; Enzyme Inhibitors; Humans; NEDD8 Protein; Neoplasms; Oncolytic Viruses	2023
Jasmonic Acid Induces Endoplasmic Reticulum Stress with Different Outcome in Cultured Normal and Tumor Epidermal Cells. Biochemistry. Biokhimiia, 2019, Volume: 84, Issue:9 Topics: Cells, Cultured; Cyclopentanes; Dose-Response Relationship, Drug; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Epidermal Cells; Humans; Neoplasms; Oxylipins; Structure-Activity Relationship	2019
Targeting oncogenic SOX2 in human cancer cells: therapeutic application. Protein & cell, 2020, Volume: 11, Issue:2 Topics: Antineoplastic Agents; Cyclopentanes; Humans; Neoplasms; Neoplastic Stem Cells; Pyrimidines; SOXB1 Transcription Factors	2020
Overexpression of ABCG2 confers resistance to pevonedistat, an NAE inhibitor. Experimental cell research, 2020, 03-15, Volume: 388, Issue:2 Topics: ATP Binding Cassette Transporter, Subfamily G, Member 2; Cyclopentanes; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Inhibitors; Humans; Neoplasm Proteins; Neoplasms; Pyrimidines; Tumor Cells, Cultured; Ubiquitin-Activating Enzymes	2020
Suramin and NF449 are IP5K inhibitors that disrupt inositol hexakisphosphate-mediated regulation of cullin-RING ligase and sensitize cancer cells to MLN4924/pevonedistat. The Journal of biological chemistry, 2020, 07-24, Volume: 295, Issue:30 Topics: Benzenesulfonates; Cullin Proteins; Cyclopentanes; Enzyme Inhibitors; HCT116 Cells; HEK293 Cells; Humans; Neoplasm Proteins; Neoplasms; Phosphotransferases (Alcohol Group Acceptor); Phytic Acid; Pyrimidines; Suramin	2020
Jasmonates induce Arabidopsis bioactivities selectively inhibiting the growth of breast cancer cells through CDC6 and mTOR. The New phytologist, 2021, Volume: 229, Issue:4 Topics: Arabidopsis; Arabidopsis Proteins; Cell Cycle Proteins; Cell Line, Tumor; Cyclopentanes; Humans; Neoplasms; Oxylipins; Plant Growth Regulators; TOR Serine-Threonine Kinases	2021
The E3 ligase C-CBL inhibits cancer cell migration by neddylating the proto-oncogene c-Src. Oncogene, 2018, Volume: 37, Issue:41 Topics: Cell Line, Tumor; Cell Movement; Cyclopentanes; Enzyme Inhibitors; Genes, src; Genes, Tumor Suppressor; Glioblastoma; Humans; Lung Neoplasms; NEDD8 Protein; Neoplasms; Proto-Oncogene Mas; Proto-Oncogene Proteins c-cbl; Pyrimidines	2018
PCI29732, a Bruton's Tyrosine Kinase Inhibitor, Enhanced the Efficacy of Conventional Chemotherapeutic Agents in ABCG2-Overexpressing Cancer Cells. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 48, Issue:6 Topics: Agammaglobulinaemia Tyrosine Kinase; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Cell Line, Tumor; Cell Survival; Cyclopentanes; Doxorubicin; Drug Resistance, Neoplasm; Humans; Mice; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasms; Phosphorylation; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; Pyrimidines; Rhodamine 123	2018
Crosstalk between Na Biochimica et biophysica acta. Molecular basis of disease, 2018, Volume: 1864, Issue:11 Topics: Cardiac Glycosides; Cell Line, Tumor; Cell Proliferation; Cyclopentanes; Fibroblasts; Gene Knockdown Techniques; HEK293 Cells; HT29 Cells; Humans; Indans; Membrane Microdomains; Membrane Proteins; Neoplasms; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction; Sodium-Potassium-Exchanging ATPase	2018
Inhibiting neddylation modification alters mitochondrial morphology and reprograms energy metabolism in cancer cells. JCI insight, 2019, 02-21, Volume: 4, Issue:4 Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclopentanes; Energy Metabolism; Female; GTP Phosphohydrolases; HEK293 Cells; Humans; Metformin; Mice; Mitochondria; Mitochondrial Dynamics; Mitochondrial Membrane Transport Proteins; Naphthoquinones; Neoplasms; Oxidative Phosphorylation; Proteolysis; Pyrimidines; Ubiquitin-Activating Enzymes; Ubiquitination; Xenograft Model Antitumor Assays	2019
Raptinal bypasses BAX, BAK, and BOK for mitochondrial outer membrane permeabilization and intrinsic apoptosis. Cell death & disease, 2019, 07-19, Volume: 10, Issue:8 Topics: Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Cyclopentanes; Cytochromes c; Fluorenes; HCT116 Cells; Humans; Mitochondria; Mitochondrial Membranes; Neoplasms; Proto-Oncogene Proteins c-bcl-2; Signal Transduction	2019
Synthesis of novel methyl jasmonate derivatives and evaluation of their biological activity in various cancer cell lines. Bioorganic chemistry, 2019, Volume: 91 Topics: Acetates; Antineoplastic Agents; Cyclopentanes; Glucose; Glycolysis; Hexokinase; Humans; Mitochondria; Neoplasms; Oxylipins; Phosphorylation; Tumor Cells, Cultured; Voltage-Dependent Anion Channel 1	2019
Synthesis, characterization and Akt phosphorylation inhibitory activity of cyclopentanecarboxylate-substituted alkylphosphocholines. Bioorganic & medicinal chemistry, 2013, Apr-01, Volume: 21, Issue:7 Topics: Antineoplastic Agents; Carboxylic Acids; Cell Line, Tumor; Cell Proliferation; Cyclopentanes; Humans; Neoplasms; Phospholipid Ethers; Phosphorylation; Phosphorylcholine; Proto-Oncogene Proteins c-akt	2013
Important cytotoxicity of novel iron(II) cyclopentadienyl complexes with imidazole based ligands. Journal of inorganic biochemistry, 2013, Volume: 129 Topics: Antineoplastic Agents; Cell Line, Tumor; Cyclopentanes; Cytotoxins; Humans; Imidazoles; Iron Compounds; Neoplasms	2013
FOLICation: engineering approved drugs as potential p53-MDM2 interaction inhibitors for cancer therapy. Medical hypotheses, 2013, Volume: 81, Issue:6 Topics: Clofazimine; Cyclopentanes; Drug Discovery; Folic Acid; Humans; Imidazoles; Indoles; Models, Molecular; Neoplasms; Piperazines; Protein Interaction Domains and Motifs; Proto-Oncogene Proteins c-mdm2; Spiro Compounds; Tumor Suppressor Protein p53	2013
Applications of pathology-assisted image analysis of immunohistochemistry-based biomarkers in oncology. Veterinary pathology, 2014, Volume: 51, Issue:1 Topics: Algorithms; Animals; Apoptosis; Aurora Kinase A; Automation; Azepines; Biomarkers, Pharmacological; Biopsy; Cyclopentanes; Drug Discovery; Drug Evaluation, Preclinical; Humans; Image Processing, Computer-Assisted; Immunohistochemistry; Mitosis; Neoplasms; Pyrimidines; Skin	2014
Methyl jasmonate and its potential in cancer therapy. Plant signaling & behavior, 2015, Volume: 10, Issue:9 Topics: Acetates; Cell Line, Tumor; Cyclopentanes; Humans; Models, Biological; Neoplasms; Oxylipins; Plant Cells	2015
Fluorine and rhenium substituted ghrelin analogues as potential imaging probes for the growth hormone secretagogue receptor. Journal of medicinal chemistry, 2009, Apr-23, Volume: 52, Issue:8 Topics: Amino Acid Sequence; Animals; CHO Cells; Cricetinae; Cricetulus; Cyclopentanes; Fluorine; Fluorine Radioisotopes; Ghrelin; Humans; Isotopes; Molecular Sequence Data; Neoplasms; Organometallic Compounds; Peptide Fragments; Radioligand Assay; Radiopharmaceuticals; Receptors, Ghrelin; Rhenium; Tomography, Emission-Computed, Single-Photon	2009
An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer. Nature, 2009, Apr-09, Volume: 458, Issue:7239 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cells, Cultured; Cullin Proteins; Cyclopentanes; Enzyme Inhibitors; Female; Humans; Mice; NEDD8 Protein; Neoplasms; Proteasome Inhibitors; Pyrimidines; Transplantation, Heterologous; Ubiquitin-Activating Enzymes; Ubiquitins	2009
Targeting NEDD8-activated cullin-RING ligases for the treatment of cancer. Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Jun-15, Volume: 15, Issue:12 Topics: Antineoplastic Agents; Boronic Acids; Bortezomib; Cullin Proteins; Cyclopentanes; Humans; NEDD8 Protein; Neoplasms; NF-kappa B; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Pyrimidines; RING Finger Domains; Signal Transduction; Ubiquitin-Activating Enzymes; Ubiquitin-Conjugating Enzymes; Ubiquitin-Protein Ligases; Ubiquitins	2009
SUMO, Ubiquitin, UBL Proteins: Implications For Human Diseases - Fifth International Conference. IDrugs : the investigational drugs journal, 2010, Volume: 13, Issue:4 Topics: Allosteric Regulation; Bacterial Toxins; Communicable Diseases; Cyclopentanes; Cytokines; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation; Heat-Shock Proteins; Hemolysin Proteins; Heterocyclic Compounds, 3-Ring; Humans; NEDD8 Protein; Neoplasms; Nuclear Proteins; Protein Processing, Post-Translational; Pyrimidines; Signal Transduction; Small Ubiquitin-Related Modifier Proteins; Tankyrases; Transcription Factors; Ubiquitin; Ubiquitin-Activating Enzymes; Ubiquitin-Conjugating Enzymes; Ubiquitin-Protein Ligases; Ubiquitination; Ubiquitins	2010
Chemical constituents from Aphanamixis grandifolia. Chemical & pharmaceutical bulletin, 2010, Volume: 58, Issue:11 Topics: Antineoplastic Agents, Phytogenic; Cell Survival; Circular Dichroism; Crystallography, X-Ray; Cyclopentanes; Humans; Magnetic Resonance Spectroscopy; Meliaceae; Models, Molecular; Naphthoquinones; Neoplasms; Triterpenes	2010
Synthesis and biological evaluation of novel exo-methylene cyclopentanone tetracyclic diterpenoids as antitumor agents. Bioorganic & medicinal chemistry letters, 2011, Jan-01, Volume: 21, Issue:1 Topics: Antineoplastic Agents; Cell Line, Tumor; Cyclopentanes; Diterpenes; Diterpenes, Kaurane; Drug Screening Assays, Antitumor; Humans; Neoplasms	2011
Synthesis of novel molecular probes inspired by harringtonolide. Organic & biomolecular chemistry, 2011, Jun-21, Volume: 9, Issue:12 Topics: Antineoplastic Agents, Phytogenic; Azides; Catalysis; Chemistry, Pharmaceutical; Click Chemistry; Copper; Cyclopentanes; Drug Discovery; Harringtonines; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Probes; Neoplasms; Plants, Medicinal; Small Molecule Libraries; Stereoisomerism; Taxaceae; Triazoles	2011
Inactivation of the Cullin (CUL)-RING E3 ligase by the NEDD8-activating enzyme inhibitor MLN4924 triggers protective autophagy in cancer cells. Autophagy, 2012, Volume: 8, Issue:11 Topics: Animals; Autophagy; Cullin Proteins; Cyclopentanes; Cytoprotection; Enzyme Activation; Enzyme Inhibitors; Gene Knockdown Techniques; Humans; Mice; Models, Biological; Neoplasms; Pyrimidines; Reactive Oxygen Species; Ubiquitin-Protein Ligases; Ubiquitins	2012
Maillard reaction products modulating the growth of human tumor cells in vitro. Chemical research in toxicology, 2003, Volume: 16, Issue:1 Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Caspases; Cell Cycle; Cyclopentanes; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Formazans; Furans; Humans; Maillard Reaction; Neoplasms; Tetrazolium Salts; Tumor Cells, Cultured	2003
[Effect of 1-isopropyl-5-methylazulene on metabolism, growth and metastasis of mouse ascites carcinoma]. Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1955, Volume: 225, Issue:3 Topics: Ascites; Biological Phenomena; Cyclopentanes; Neoplasms; Neoplasms, Second Primary; Physiological Phenomena	1955
Influences of anticancer agents on the activities of liver catalase, uricase, and xanthine oxidase in normal and tumor-bearing mice. Gan, 1963, Volume: 54 Topics: Aminopterin; Animals; Antineoplastic Agents; Azaguanine; Carboxylic Acids; Carcinoma, Ehrlich Tumor; Catalase; Cyclopentanes; Liver; Mercaptopurine; Methotrexate; Mice; N-Glycosyl Hydrolases; Neoplasms; Oxidoreductases; Thiotepa; Urate Oxidase; Xanthine Oxidase	1963
Effect of sarcomycin derivatives on solid tumors. Gan, 1962, Volume: 53 Topics: Animals; Antineoplastic Agents; Carboxylic Acids; Cyclopentanes; Neoplasms	1962
[AUTOPSY CASE OF PULMONARY TUBERCULOSIS WITH METASTASIS OF SARCOMA OF THE UPPER ARM TO THE LUNGS AND PLEURAL CAVITY]. Rinsho hoshasen. Clinical radiography, 1963, Volume: 8 Topics: Aminosalicylic Acid; Aminosalicylic Acids; Arm; Autopsy; Carboxylic Acids; Cyclopentanes; Lung Neoplasms; Neoplasm Metastasis; Neoplasms; Pathology; Penicillins; Pleural Cavity; Pleural Neoplasms; Radiography, Thoracic; Sarcoma; Streptomycin; Surgical Procedures, Operative; Tuberculosis, Pulmonary	1963
STUDIES ON THE ACTION OF NEW SARCOMYCIN DERIVATIVES. Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20 Topics: Animals; Carboxylic Acids; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Cyclopentanes; Fibrosarcoma; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mice; Neoplasms; Neoplasms, Experimental; Pharmacology; Rats; Research; Sarcoma; Sarcoma, Experimental	1964
FURTHER STUDIES ON THE CARCINOGENIC ACTION OF CERTAIN LACTONES AND RELATED SUBSTANCES IN THE RAT AND MOUSE. British journal of cancer, 1965, Volume: 19 Topics: Aflatoxins; Animals; Antitoxins; Aspergillus; Carboxylic Acids; Carcinogens; Coumarins; Cyclopentanes; Injections, Subcutaneous; Lactones; Mice; Neoplasms; Neoplasms, Experimental; Pharmacology; Rats; Research; Toxins, Biological	1965
Novel achiral titanocene anti-cancer drugs synthesised from bis-N,N-dimethylamino fulvene and lithiated heterocyclic compounds. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2008, Volume: 21, Issue:2 Topics: Antineoplastic Agents; Cell Line, Tumor; Cyclopentanes; Drug Evaluation, Preclinical; Heterocyclic Compounds; Humans; Inhibitory Concentration 50; Molecular Conformation; Molecular Structure; Neoplasms; Organometallic Compounds	2008
Methyl jasmonate binds to and detaches mitochondria-bound hexokinase. Oncogene, 2008, Aug-07, Volume: 27, Issue:34 Topics: Acetates; Adenosine Triphosphate; Animals; Cell Death; Cyclopentanes; DNA Damage; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Hexokinase; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mitochondria; Mitochondrial Swelling; Neoplasms; Oxylipins; Protein Binding; Rats; Transfection; Tumor Cells, Cultured; Voltage-Dependent Anion Channels	2008
Disruption of the hexokinase-VDAC complex for tumor therapy. Oncogene, 2008, Aug-07, Volume: 27, Issue:34 Topics: Acetates; Cyclopentanes; Hexokinase; Humans; Models, Biological; Multiprotein Complexes; Neoplasms; Oxylipins; Phytotherapy; Plant Extracts; Protein Binding; Voltage-Dependent Anion Channels	2008
70 kDa heat shock cognate protein is a transformation-associated antigen and a possible target for the host's anti-tumor immunity. Journal of immunology (Baltimore, Md. : 1950), 1993, Nov-15, Volume: 151, Issue:10 Topics: Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Biological Transport; Brefeldin A; Cyclopentanes; Cytotoxicity, Immunologic; Heat-Shock Proteins; Molecular Weight; Neoplasms; Rats; Rats, Inbred Strains; T-Lymphocytes	1993
Antitumor efficacy in vitro and in vivo of falconensones, a new type of polyene. Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:11 Topics: Animals; Antineoplastic Agents; Body Weight; Cell Division; Cyclopentanes; Dose-Response Relationship, Drug; Female; HL-60 Cells; Humans; Ketones; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms; Polyenes; Specific Pathogen-Free Organisms; Time Factors; Treatment Outcome; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2001
Studies on the inhibition of tumor cell growth and microtubule assembly by 3-hydroxy-4-[(E)-(2-furyl)methylidene]methyl-3-cyclopentene-1,2-dione, an intensively coloured Maillard reaction product. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2002, Volume: 40, Issue:1 Topics: Animals; Antineoplastic Agents; Brain Chemistry; Breast Neoplasms; Cattle; Cell Cycle; Cell Division; Cyclopentanes; DNA Damage; DNA-Binding Proteins; Dose-Response Relationship, Drug; ets-Domain Protein Elk-1; Female; Furans; Humans; Maillard Reaction; Microtubules; Neoplasms; Phosphorylation; Polymers; Proto-Oncogene Proteins; Transcription Factors; Tubulin; Tumor Cells, Cultured	2002
Chemoimmunotherapy of cancer. 1. Journal of medicinal chemistry, 1974, Volume: 17, Issue:9 Topics: Alkylating Agents; Animals; Antibody Formation; Antigen-Antibody Reactions; Cattle; Cyclopentanes; Dinitrophenols; Erythrocytes; gamma-Globulins; Haptens; Hemolysis; Humans; Immune Sera; Immunodiffusion; Immunotherapy; Male; Mustard Compounds; Neoplasms; Precipitin Tests; Protein Binding; Rabbits; Serum Albumin, Bovine; Sheep	1974