Compounds > cyclopentane
Page last updated: 2024-08-21

cyclopentane and Melanoma

cyclopentane has been researched along with Melanoma in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (35.71)18.2507
2000's0 (0.00)29.6817
2010's7 (50.00)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Alnemri, ES; Aplin, AE; Cai, W; Kotas, D; Pomante, D; Tiago, M; Vernon, M; Wilski, NA1
Assumpção, ALFV; Huelsmeyer, MK; Jia, S; Lu, Z; Pan, X; Vail, DM; Van Hesteren, MA; Wood, EA1
Custódio, JBA; Ribeiro, MPC; Santos, AE1
Carson, WE; Duggan, MC; Olaverria Salavaggione, GN1
Bhatia, S; Boasberg, P; Dezube, BJ; Faessel, H; Hamid, O; Mulligan, G; Pavlick, AC; Pickard, MD; Thompson, JA1
Abbas, T; Benamar, M; Corbett, P; Du, K; Gioeli, D; Guessous, F; Obeid, J; Slingluff, CL1
Bagby, SM; Berger, A; Blakemore, SJ; Eckhardt, SG; Klauck, PJ; McDonald, A; Micel, LN; Pitts, TM; Selby, HM; Smith, PF; Spreafico, A; Tan, AC; Tentler, JJ; Wong, KM1
Alberto, R; Can, D; Fernandes, C; N'Dongo, HW; Raposinho, PD; Santos, I; Schmutz, P; Spingler, B1
Bernard, H; Blank, JL; Bouck, DC; Cosmopoulos, K; Garcia, K; Hather, G; Lightcap, ES; Liu, R; Liu, XJ; Milhollen, MA; Narayanan, U; Tayber, O1
Gordon, CM; Lloyd, KO1
Freeze, HH; Sampath, D; Varki, A1
Sjoberg, ER; Varki, A1
Calafat, J; Dusseljee, S; Fernandez-Borja, M; Janssen, H; Neefjes, J; Oomen, L; Tulp, A; Verwoerd, D; Wubbolts, R1
Lechler-Osborn, S; Lutz, MS; Mills, SE; Young, WW1

Trials

1 trial(s) available for cyclopentane and Melanoma

ArticleYear
A phase I study of the investigational NEDD8-activating enzyme inhibitor pevonedistat (TAK-924/MLN4924) in patients with metastatic melanoma.
    Investigational new drugs, 2016, Volume: 34, Issue:4

    Topics: Adult; Aged; Cyclopentanes; Female; Humans; Male; Maximum Tolerated Dose; Melanoma; Middle Aged; Pyrimidines; Treatment Outcome; Ubiquitin-Activating Enzymes

2016

Other Studies

13 other study(ies) available for cyclopentane and Melanoma

ArticleYear
Raptinal Induces Gasdermin E-Dependent Pyroptosis in Naïve and Therapy-Resistant Melanoma.
    Molecular cancer research : MCR, 2022, 12-02, Volume: 20, Issue:12

    Topics: Animals; Cyclopentanes; Cytokines; Humans; Melanoma; Mice; Pyroptosis

2022
Pevonedistat targeted therapy inhibits canine melanoma cell growth through induction of DNA re-replication and senescence.
    Veterinary and comparative oncology, 2020, Volume: 18, Issue:3

    Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Survival; Cyclopentanes; DNA Replication; Dog Diseases; Dogs; Enzyme Inhibitors; Melanoma; Mouth Neoplasms; Pyrimidines

2020
The activation of the G protein-coupled estrogen receptor (GPER) inhibits the proliferation of mouse melanoma K1735-M2 cells.
    Chemico-biological interactions, 2017, Nov-01, Volume: 277

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cyclopentanes; Melanoma; Mice; Quinolines; Receptors, Estrogen; Receptors, G-Protein-Coupled

2017
Analysis of MLN4924 (pevonedistat) as a potential therapeutic agent in malignant melanoma.
    Melanoma research, 2018, Volume: 28, Issue:5

    Topics: Cell Line, Tumor; Cyclopentanes; Enzyme Inhibitors; Humans; Melanoma; Pyrimidines; Skin Neoplasms; Survival Rate

2018
Inactivation of the CRL4-CDT2-SET8/p21 ubiquitylation and degradation axis underlies the therapeutic efficacy of pevonedistat in melanoma.
    EBioMedicine, 2016, Volume: 10

    Topics: Animals; Antineoplastic Agents; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Cyclopentanes; Disease Models, Animal; Female; Gene Expression; Gene Silencing; Genes, ras; Histone-Lysine N-Methyltransferase; Humans; Kaplan-Meier Estimate; Melanoma; Mice; Mutation; Nuclear Proteins; Prognosis; Protein Stability; Proto-Oncogene Proteins B-raf; Pyrimidines; RNA Interference; Ubiquitin-Protein Ligases; Ubiquitination; Xenograft Model Antitumor Assays

2016
Targeting the protein ubiquitination machinery in melanoma by the NEDD8-activating enzyme inhibitor pevonedistat (MLN4924).
    Investigational new drugs, 2017, Volume: 35, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Cyclopentanes; Gene Expression Regulation, Neoplastic; Humans; Melanoma; Pyrimidines; Ubiquitin-Activating Enzymes; Ubiquitination

2017
Preparation and biological evaluation of cyclopentadienyl-based 99mTc-complexes [(Cp-R)99mTc(CO)3] mimicking benzamides for malignant melanoma targeting.
    Nuclear medicine and biology, 2010, Volume: 37, Issue:3

    Topics: Animals; Benzamides; Cell Line, Tumor; Cyclopentanes; Drug Delivery Systems; Drug Evaluation, Preclinical; Isotope Labeling; Melanoma; Metabolic Clearance Rate; Mice; Organ Specificity; Radiopharmaceuticals; Tissue Distribution

2010
Novel DNA damage checkpoints mediating cell death induced by the NEDD8-activating enzyme inhibitor MLN4924.
    Cancer research, 2013, Jan-01, Volume: 73, Issue:1

    Topics: Antineoplastic Agents; Blotting, Western; Cell Cycle Checkpoints; Cell Line, Tumor; Cyclopentanes; DNA Damage; Flow Cytometry; Humans; Melanoma; NEDD8 Protein; Polymerase Chain Reaction; Pyrimidines; Ubiquitins

2013
Endocytosis and recycling of gangliosides in a human melanoma cell line: inhibitory effect of brefeldin A and monensin.
    Archives of biochemistry and biophysics, 1994, Volume: 315, Issue:2

    Topics: Antibodies, Monoclonal; Antibody Specificity; Brefeldin A; Carbohydrate Sequence; Cyclopentanes; Endocytosis; Gangliosides; Golgi Apparatus; Humans; In Vitro Techniques; Melanoma; Molecular Sequence Data; Monensin; Tumor Cells, Cultured

1994
Alpha- and beta-xylosides alter glycolipid synthesis in human melanoma and Chinese hamster ovary cells.
    The Journal of biological chemistry, 1993, Jan-25, Volume: 268, Issue:3

    Topics: Animals; Anions; Brefeldin A; CHO Cells; Cricetinae; Cyclopentanes; G(M3) Ganglioside; Galactose; Glucuronidase; Glycolipids; Glycosides; Humans; Hymecromone; Macrophages; Melanoma; Neuroblastoma; PC12 Cells; Tritium; Tumor Cells, Cultured

1993
Kinetic and spatial interrelationships between ganglioside glycosyltransferases and O-acetyltransferase(s) in human melanoma cells.
    The Journal of biological chemistry, 1993, May-15, Volume: 268, Issue:14

    Topics: Acetyltransferases; Brefeldin A; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cyclopentanes; Cytidine Monophosphate N-Acetylneuraminic Acid; Galactose; Gangliosides; Glycosyltransferases; Golgi Apparatus; Humans; Kinetics; Lipid Metabolism; Lipids; Melanoma; Models, Biological; Radioisotope Dilution Technique; Tumor Cells, Cultured; Uridine Diphosphate N-Acetylglucosamine

1993
Direct vesicular transport of MHC class II molecules from lysosomal structures to the cell surface.
    The Journal of cell biology, 1996, Volume: 135, Issue:3

    Topics: Biological Transport; Brefeldin A; Cell Membrane; Cyclopentanes; Endosomes; Green Fluorescent Proteins; HLA-DR1 Antigen; Humans; Intracellular Membranes; Luminescent Proteins; Lysosomes; Melanoma; Membrane Fusion; Microscopy, Confocal; Protein Synthesis Inhibitors; Recombinant Fusion Proteins; Tumor Cells, Cultured

1996
Use of brefeldin A to define sites of glycosphingolipid synthesis: GA2/GM2/GD2 synthase is trans to the brefeldin A block.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:17

    Topics: Animals; Anti-Bacterial Agents; Brefeldin A; Carbohydrate Conformation; Carbohydrate Sequence; Cell Line; Cyclopentanes; Endoplasmic Reticulum; Galactosyltransferases; Glycosphingolipids; Golgi Apparatus; Humans; Melanoma; Molecular Sequence Data; N-Acetylgalactosaminyltransferases; Polypeptide N-acetylgalactosaminyltransferase

1990