cyclopentane has been researched along with Disease Models, Animal in 105 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (0.95) | 18.2507 |
| 2000's | 28 (26.67) | 29.6817 |
| 2010's | 64 (60.95) | 24.3611 |
| 2020's | 12 (11.43) | 2.80 |
| Authors | Studies |
|---|---|
| Ahmad, S; Al-Harrasi, A; Ali, G; Khan, A; Ullah, R | 1 |
| Li, H; Mao, D; Xu, J; Yu, C; Zhang, L; Zhang, Q | 1 |
| Gu, ZW; Hao, LY; Wang, YX | 1 |
| Darvishi, P; Pourfathollah, AA; Yousefi, S; Yousefi, Z | 1 |
| Broughton, BRS; Chrissobolis, S; Diep, H; Dinh, QN; Drummond, GR; Judkins, CP; Kim, HA; Saini, N; Sobey, CG; Vinh, A | 1 |
| Elfar, N; Haffez, H; Hassan, ZA; Taha, H | 1 |
| Aluko, OM; Umukoro, S | 1 |
| Chester, JA; Ding, Z; Knipp, GT; van Rijn, RM; Watts, VJ | 1 |
| Li, D; Li, K; Wang, J; Wang, Q; Wang, Y; Xie, S; Zhao, J; Zuo, Z | 1 |
| Almutlaq, RN; Butt, MK; Daugherty, EM; De Miguel, C; Gohar, EY; Jin, C; Pollock, DM; Pollock, JS | 1 |
| Chen, Y; Feng, W; Hua, R; Huo, Y; Jiang, H; Lin, Y; Yang, X; Yin, B; Zhang, J | 1 |
| Augert, A; Basom, R; Eastwood, E; MacPherson, D; Norton, JP; Rudin, CM | 1 |
| Ji, X; Tu, Y; Wang, K; Wang, X; Xie, L; Zeng, X; Zhang, J; Zhu, L; Zhu, M | 1 |
| Ajayi, AM; Alabi, AO; Eduviere, AT; Oluwole, OG; Umukoro, S | 1 |
| Chen, K; Dai, W; Feng, J; Guo, C; Li, J; Li, S; Liu, T; Lu, J; Wang, F; Wu, L; Xia, Y; Xu, L; Xu, S; Zhou, Y | 1 |
| Aluko, OM; Annafi, OS; Eduviere, AT; Omorogbe, O; Umukoro, S | 1 |
| Adebesin, A; Adeoluwa, OA; Eduviere, AT; Umukoro, S | 1 |
| Govorkova, EA; Marathe, BM; Mostafa, HH; Pascua, PNQ; Russell, CJ; Vogel, P; Webby, RJ | 1 |
| Adebesin, A; Ajayi, AM; Olonode, EO; Omorogbe, O; Umukoro, S | 1 |
| Chen, WC; Chen, YH; Hsu, SH; Hung, LC; Lee, JC; Lin, CK; Tseng, CK; Wang, SN; Wang, WH; Wu, YH | 1 |
| Apland, JP; Aroniadou-Anderjaska, V; Braga, MFM; Figueiredo, TH; Pidoplichko, VI; Rossetti, K | 1 |
| Apland, JP; Aroniadou-Anderjaska, V; Braga, MFM; De Araujo Furtado, M; Figueiredo, TH | 1 |
| Liu, J; Orange, M; Wu, Z; Yang, B; Yao, M; Yi, F; Zheng, Y; Zhu, H | 1 |
| Chen, XR; Han, QQ; Huang, HJ; Li, HY; Ma, SL; Wang, HM; Wang, J; Wang, YL; Yu, J; Yu, R | 1 |
| Fan, X; Gong, X; Ke, H; Li, C; Liu, T; Wang, Q; Xiaoyan, L; Zhang, J | 1 |
| Albert, V; Behrens, M; Bland, JS; Fang, M; Galmozzi, A; Godio, C; Grayson, N; Kim, SM; Kim, W; Kok, BP; Littlejohn, NK; Meyerhof, W; Saez, E; Siuzdak, G; Srinivasan, S | 1 |
| Cieślik, P; Kalinowski, L; Kusek, M; Pelikant-Małecka, I; Pilc, A; Płoska, A; Radulska, A; Sławiński, J; Tokarski, K; Wierońska, JM; Woźniak, M; Żołnowska, B | 1 |
| Cao, L; Ma, CG; Miao, Q; Song, LJ; Sui, RX; Wang, J; Wang, Q; Xiao, BG; Xiao, W; Yu, JW | 1 |
| Adams, J; Al-Shamma, H; Carroll, C; Komori, HK; Lehmann-Bruinsma, K; Peyrin-Biroulet, L; Solomon, M | 1 |
| Hao, R; Li, R; Li, X; Qian, F; Song, Y; Sun, L; Wu, Y; Yang, X; Ye, RD | 1 |
| Kim, IM; Li, J; Littlejohn, R; Liu, J; Ma, W; Stansfield, BK; Su, H; Weintraub, NL; Zhou, J; Zou, J | 1 |
| Ahmad, S; da Silva, JS; Ferrario, CM; Groban, L; Sudo, RT; Sun, X; Varagic, J; Wang, H; Zapata-Sudo, G | 1 |
| Huang, H; Li, WZ; Wu, WY; Wu, YY; Yin, YY | 1 |
| Dolan, S; Goldie, M | 1 |
| Klein, J; Koch, KA; Schwarzkopf, TM | 1 |
| Ao, GZ; Fan, JH; Gao, XM; Gu, WW; Ishidoh, K; Nobuhiko, K; Sun, SC; Zhang, HL; Zhou, Q; Zhu, YM | 1 |
| Chen, J; Han, Q; Hu, F; Lei, T; Li, Z; Liu, S; Zhang, H; Zhang, Q; Zhou, M | 1 |
| Baba, K; Hasegawa, T; Homma, T; Izawa, M; Kamimori, H; Kanazu, T; Kida, H; Kitano, M; Kobayashi, M; Kodama, M; Noshi, T; Okazaki, K; Sakoda, Y; Sato, A; Seki, T; Tsuji, M; Yamano, Y; Yoshida, R | 1 |
| Arán, VJ; Escario, JA; Gómez-Barrio, A; Ibáñez-Escribano, A; Marrero-Ponce, Y; Meneses-Marcel, A; Nogal-Ruiz, JJ | 1 |
| Beggiato, S; Ferrante, A; Ferraro, L; Martire, A; Pepponi, R; Popoli, P; Tebano, MT; Varani, K; Vincenzi, F | 1 |
| Jiang, M; Li, J; Liu, W; Liu, Y; Luo, C; Mo, Z; Peng, J; Peng, Q; Yung, KK | 1 |
| Bayless, A; Campbell, EL; Colgan, SP; Curtis, VF; Ehrentraut, SF; Glover, LE; Kelly, CJ; Kominsky, DJ | 1 |
| Homma, T; Kitano, M; Kobayashi, M; Naito, A; Onishi, M; Sato, A; Taniguchi, K; Yoshinaga, T | 1 |
| Aluko, OM; Eduviere, AT; Owoeye, O; Umukoro, S | 1 |
| Boguszewski, PM; Domin, H; Jantas, D; Kozniewska, E; Przykaza, Ł; Śmiałowska, M | 1 |
| Ao, GZ; Gu, WW; Li, LS; Li, X; Liu, ZH; Lu, SQ; Luo, Y; Ni, Y; Sun, WZ; Zhang, HL; Zhou, XY; Zhu, YM | 1 |
| Acher, F; Gruca, P; Lasoń-Tyburkiewicz, M; Marciniak, M; Papp, M; Pilc, A; Wierońska, JM; Woźniak, M | 1 |
| Budish, RA; Chappell, MC; Hutson, DD; Kashyap, S; Lindsey, SH; Liu, L; Miller, KS; Murphy, B; Trask, AJ; Trimmer, EH; Zimmerman, MA | 1 |
| Chen, P; Chen, X; Dong, Z; Hao, Q; Hoffman, RM; Hu, T; Jeong, LS; Jia, L; Li, P; Liang, Y; Ma, Y; Qi, H; Wang, J; Yang, M; Yang, S; Yu, J; Zhang, J; Zhang, P; Zhang, Y; Zhao, H | 1 |
| Cheng, M; Fan, R; Hu, S; Lin, Y; Liu, X; Pei, Y; Tao, R; Wang, L; Wang, Z; Zhang, M; Zhang, T; Zheng, S; Zhong, J; Zhou, J | 1 |
| Abbas, T; Benamar, M; Corbett, P; Du, K; Gioeli, D; Guessous, F; Obeid, J; Slingluff, CL | 1 |
| Chen, R; Chen, T; Du, Q; Hao, Y; Li, J; Li, R; Li, Y; Li, Z; Xie, H; Yang, Z; Zhong, N | 1 |
| Cheng, Q; Kang, WB; Liu, G; Meng, J; Tian, Z; Wang, XS; Zhang, K; Zhao, JN | 1 |
| Shui, L; Song, Z; Tai, F; Wang, S; Wu, R | 1 |
| Baeyens, JM; Cobos, EJ; Entrena, JM; González-Cano, R; Nieto, FR; Sánchez-Fernández, C; Yeste, S | 1 |
| Isoda, N; Kanazu, T; Kida, H; Kobayashi, M; Kodama, M; Nomura, N; Noshi, T; Okamatsu, M; Sakoda, Y; Sato, A; Soda, K; Yamano, Y; Yoshida, R | 1 |
| Aspichueta, P; Aurrekoetxea, I; Barbier-Torres, L; Beraza, N; Caballeria, J; Crespo, J; de Davalillo, SL; Delgado, TC; Duce, AM; Fernández-Ramos, D; Fernández-Tussy, P; Gutiérrez-de Juan, V; Iruzubieta, P; Lopitz-Otsoa, F; Lu, SC; Martínez-Chantar, ML; Mato, JM; Simon, J; Taibo, D; Varela-Rey, M; Villa, E; Zubiete-Franco, I | 1 |
| Bot, I; de Lange, EC; de Vries, H; de Witte, WE; Heitman, LH; IJzerman, AP; Kröner, MJ; Kuiper, J; Ortiz Zacarías, NV; Stamos, D; van der Berg, DJ; van der Velden, D; van Santbrink, PJ | 1 |
| Davis, JS; Dong, J; He, C; Hua, G; Huang, C; Karpf, AR; Lv, X; Remmenga, SW; Rodabough, KJ; Wang, C; Wang, Z | 1 |
| Carai, MA; Colombo, G; Fantini, N; Froestl, W; Gessa, GL; Maccioni, P | 1 |
| Frauli, M; Hess, G; Kłodzińska, A; Neuville, P; Pałucha-Poniewiera, A; Pilc, A; Schann, S; Stachowicz, K; Tokarski, K | 1 |
| Amalric, M; Brotchie, JM; Johnston, TH; Lopez, S; Neuville, P; Schann, S; Turle-Lorenzo, N | 1 |
| Bramanti, P; Cuzzocrea, S; Di Paola, R; Esposito, E; Genovese, T; Mazzon, E; Meli, R; Muià, C | 1 |
| Beitz, AJ; Han, HJ; Kim, HW; Kim, KW; Kwon, YB; Lee, JH; Roh, DH; Seo, HS; Yoon, SY | 2 |
| Chen, SR; Pan, HL; Samoriski, G | 1 |
| Alam, M; Danysz, W; Dekundy, A; Schmidt, WJ | 1 |
| Liu, LG; Rong, S; Sun, ZD; Xie, BJ; Xu, JQ; Zhang, L; Zhang, YJ | 1 |
| Novák, K; Pałucha-Poniewiera, A; Pilc, A | 1 |
| Blasko, E; Dennis, MK; Gualtieri, G; Halks-Miller, M; Haskell, CA; Horuk, R; Karpus, WJ; Leung, S; Mahmoudi, M; Prossnitz, ER | 1 |
| Deschamps, AM; Murphy, E | 1 |
| Blakemore, DC; Bryans, JS; Carnell, P; Field, MJ; Kinsella, N; Kinsora, JK; Meltzer, LT; Osborne, SA; Thompson, LR; Williams, SC | 1 |
| Bland, JS; Darland, G; Desai, A; Konda, VR; Tripp, ML | 1 |
| Honda, S; Kawaura, K; Shirasaki, T; Soeda, F; Takahama, K | 1 |
| Babu, YS; Hurst, BL; Klumpp, K; Morrey, JD; Smee, DF; Tarbet, EB; Wong, MH | 1 |
| Babu, YS; Bantia, S; Kellogg, D; Parker, CD | 1 |
| Akinyinka, AO; Aladeokin, AC; Umukoro, S | 1 |
| Babu, YS; Bantia, S; Ilyushina, NA; Kellogg, D; Parker, C; Upshaw, R | 1 |
| Froestl, W; Kusek, M; Pilc, A; Tokarski, K; Wabno, J; Wierońska, JM | 1 |
| Klein, J; Lang, D; Schubert-Zsilavecz, M; Ude, C; Wurglics, M | 1 |
| Aas, P; Enger, S; Jonassen, M; Myhrer, T | 1 |
| Cho, BJ; Cho, HJ; Choi, SH; Jang, HC; Kang, SM; Kim, HS; Kim, M; Kim, YB; Lim, S; Park, HS; Park, KS; Shin, H; Yoon, JW | 1 |
| Amalric, M; Jouve, L; Kerkerian-Legoff, L; Lopez, S; Salin, P; Turle-Lorenzo, N | 1 |
| Babu, YS; Furuta, Y; Maekawa, M; Morrey, JD; Smee, DF; Tarbet, EB | 1 |
| Arterburn, JB; Benamar, K; Brailoiu, E; Brailoiu, GC; Deliu, E; Dun, NJ; Oprea, TI | 1 |
| Benmohamed, R; Benmohammed, R; Kirsch, DR; Silverman, RB; Trippier, PC | 1 |
| Aas, P; Enger, S; Myhrer, T | 1 |
| Cai, C; Hou, C; Johnson, D; Kang, FA; McKenney, S; O'Neill, JC; Opas, E; Sui, Z | 1 |
| Chandrasekaran, K; Chinopoulos, C; Drieu, K; Fiskum, G; Mehrabian, Z; Spinnewyn, B | 1 |
| Cryan, JF; Froestl, W; Kaupmann, K; Mombereau, C; Sansig, G; van der Putten, H | 1 |
| Arnold, CS; Bantia, S; Chand, P; Parker, CD; Upshaw, R | 1 |
| Gubareva, LV; Hayden, FG; Mishin, VP; Signorelli, KL | 1 |
| Cryan, JF; Kaupmann, K; Lhuillier, L; Mombereau, C | 1 |
| Abdalla, DS; Baldissera, LP; Bock, PM; Cruz, LA; Curi, R; Gutierrez, LL; Heck, TG; Homem de Bittencourt, PI; Janner, DR; Krause, MS; Lagranha, CJ; Lagranha, DJ; Lima, T; Maslinkiewicz, A; Peralta, JS; Scola, G; Senna, SM; Tavares, AM | 1 |
| Abraham, S; Cohen, G; Dachir, S; Gilat, E; Herskovitz, M; Kapon, J; Levy, A; Raveh, L; Teitelbaum, Z | 1 |
| Chojnacka-Wójcik, E; Kłak, K; Pilc, A; Stachowicz, K | 1 |
| Buckley, F; Sacks, B | 1 |
| Feustel, PJ; Kimelberg, HK; Zhang, H; Zhang, Y | 1 |
| Fei, XF; Gu, ZL; Li, LY; Liang, ZQ; Qin, ZH; Zhao, XL | 1 |
| Chapman, ID; Cook, NS | 1 |
| Babu, YS; Bailey, KW; Barnard, DL; Huffman, JH; Morrey, JD; Sidwell, RW; Smee, DF | 1 |
| Furuta, K; Hatanaka, H; Ishikawa, Y; Nakatsuka, D; Namura, S; Satoh, T; Sugie, Y; Suzuki, M; Tomokiyo, K; Watanabe, Y | 1 |
| Bailey, K; Bush, K; Drusano, GL; Preston, SL; Sidwell, RW; Smee, D | 1 |
| Bush, K; Goloubeva, OG; Govorkova, EA; Leneva, IA; Webster, RG | 1 |
| Britti, D; Caputi, AP; Chatterjee, PK; Cuzzocrea, S; Di Paola, R; Dugo, L; Mazzon, E; Serraino, I; Thiemermann, C; Wayman, NS | 1 |
1 review(s) available for cyclopentane and Disease Models, Animal
| Article | Year |
|---|---|
[Novel antidepressant-like action of drugs possessing GIRK channel blocking action in rats].
Topics: Animals; Antidepressive Agents; Biogenic Monoamines; Brain; Cyclopentanes; Disease Models, Animal; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Humans; Male; Piperidines; Rats; Rats, Wistar | 2010 |
1 trial(s) available for cyclopentane and Disease Models, Animal
| Article | Year |
|---|---|
Bilobalide, a unique constituent of Ginkgo biloba, inhibits inflammatory pain in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; Carrageenan; Cyclopentanes; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Edema; Furans; Ginkgolides; Hindlimb; Hyperalgesia; Inflammation; Male; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Sensory System Agents; Vocalization, Animal | 2013 |
103 other study(ies) available for cyclopentane and Disease Models, Animal
| Article | Year |
|---|---|
Cyclopentanone Derivative Attenuates Memory Impairment by Inhibiting Amyloid Plaques Formation in the 5xFAD Mice.
Topics: Alzheimer Disease; Animals; Cyclopentanes; Disease Models, Animal; Memory Disorders; Mice; Mice, Transgenic; Plaque, Amyloid | 2021 |
Bilobalide alleviates IL-17-induced inflammatory injury in ATDC5 cells by downregulation of microRNA-125a.
Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Survival; Cyclopentanes; Disease Models, Animal; Down-Regulation; Furans; Ginkgo biloba; Ginkgolides; Inflammation; Interleukin-17; JNK Mitogen-Activated Protein Kinases; Matrix Metalloproteinases; Mice; MicroRNAs; Molecular Mimicry; NF-kappa B; Plant Extracts; Signal Transduction; Spondylitis, Ankylosing; Transfection | 2019 |
The environmental hormone nonylphenol interferes with the therapeutic effects of G protein-coupled estrogen receptor specific agonist G-1 on murine allergic rhinitis.
Topics: Animals; Cyclopentanes; Disease Models, Animal; Drug Interactions; Endocrine Disruptors; Estrogens; Female; Humans; Mice; Nasal Mucosa; Ovalbumin; Phenols; Quinolines; Receptors, Estrogen; Receptors, G-Protein-Coupled; Rhinitis, Allergic; T-Lymphocytes, Regulatory; Th2 Cells | 2020 |
Effect of methyl jasmonate and 3-bromopyruvate combination therapy on mice bearing the 4 T1 breast cancer cell line.
Topics: Acetates; Affinity Labels; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cyclopentanes; Disease Models, Animal; Female; Mice; Oxylipins; Plant Growth Regulators; Pyruvates; Xenograft Model Antitumor Assays | 2020 |
Aldosterone-induced hypertension is sex-dependent, mediated by T cells and sensitive to GPER activation.
Topics: Aldosterone; Animals; Antihypertensive Agents; Benzodioxoles; Blood Pressure; Cyclopentanes; Disease Models, Animal; Estrogen Antagonists; Female; Homeodomain Proteins; Hypertension; Male; Mice, Inbred C57BL; Mice, Knockout; Ovariectomy; Quinolines; Receptors, Estrogen; Receptors, G-Protein-Coupled; Sex Factors; Signal Transduction; T-Lymphocytes | 2021 |
Raptinal silver nanoparticles: new therapeutic advances in hepatocellular carcinoma mouse model.
Topics: alpha-Fetoproteins; Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Caspase 3; Cyclopentanes; Cytochromes c; Disease Models, Animal; Fluorenes; Gene Expression Regulation, Neoplastic; Hepatocytes; Liver; Liver Neoplasms; Male; Metal Nanoparticles; Mice; Silver; Tumor Suppressor Protein p53 | 2021 |
Role of purinergic signaling pathways in the adaptogenic-like activity of methyl jasmonate in rats exposed to unpredictable chronic mild stress.
Topics: Acetates; Animals; Antioxidants; Behavior, Animal; Chronic Disease; Cyclopentanes; Depression; Disease Models, Animal; Injections, Intraperitoneal; Male; Neuroprotective Agents; Oxylipins; Rats; Rats, Wistar; Receptors, Purinergic; Signal Transduction; Stress, Psychological | 2020 |
The CUL3/neddylation inhibitor MLN4924 reduces ethanol-induced locomotor sensitization and inflammatory pain allodynia in mice.
Topics: Alcoholism; Animals; Central Nervous System Depressants; Central Nervous System Sensitization; Cullin Proteins; Cyclopentanes; Disease Models, Animal; Enzyme Inhibitors; Ethanol; Hyperalgesia; Inflammation; Locomotion; Male; Mice; Mice, Inbred BALB C; NEDD8 Protein; Pyrimidines | 2021 |
Enhanced anti-amnestic effect of donepezil by Ginkgo biloba extract (EGb 761) via further improvement in pro-cholinergic and antioxidative activities.
Topics: Acetylcholinesterase; Amnesia; Animals; Antioxidants; Behavior, Animal; Brain; Cell Line; Cholinergic Agents; Cognitive Dysfunction; Cyclopentanes; Disease Models, Animal; Donepezil; Drug Therapy, Combination; Furans; Ginkgo biloba; Ginkgolides; Humans; Male; Malondialdehyde; Maze Learning; Nootropic Agents; Plant Extracts; Rats, Wistar; Superoxide Dismutase | 2021 |
Activation of G protein-coupled estrogen receptor 1 ameliorates proximal tubular injury and proteinuria in Dahl salt-sensitive female rats.
Topics: Albuminuria; Animals; Arterial Pressure; Cell Adhesion Molecules; Cyclopentanes; Disease Models, Animal; Female; Hypertension; Kidney Diseases; Kidney Glomerulus; Kidney Tubules, Proximal; Quinolines; Rats, Inbred Dahl; Receptors, G-Protein-Coupled; Signal Transduction; Sodium Chloride, Dietary | 2021 |
Neddylation pathway alleviates chronic pancreatitis by reducing HIF1α-CCL5-dependent macrophage infiltration.
Topics: Animals; Cell Line; Chemokine CCL5; Chemotaxis; Cyclopentanes; Disease Models, Animal; Enzyme Inhibitors; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Macrophages; Mice, Inbred C57BL; Pancreas; Pancreatitis, Chronic; Phenotype; Pyrimidines; Signal Transduction; Ubiquitin-Activating Enzymes; Ubiquitination | 2021 |
Protein neddylation as a therapeutic target in pulmonary and extrapulmonary small cell carcinomas.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Carcinoma, Small Cell; Cell Death; Cell Line, Tumor; COP9 Signalosome Complex; Cyclopentanes; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Heterografts; Humans; Lung Neoplasms; Mice; NEDD8 Protein; Neuroendocrine Cells; Proteins; Pyrimidines; Repressor Proteins; Sequence Deletion | 2021 |
MLN4924 inhibits hedgehog signaling pathway and activates autophagy to alleviate mouse laser-induced choroidal neovascularization lesion.
Topics: Animals; Autophagy; Biomarkers; Choroidal Neovascularization; Cyclopentanes; Disease Management; Disease Models, Animal; Disease Susceptibility; Endothelial Cells; Hedgehog Proteins; Lasers; Mice; Pyrimidines; Retinal Pigment Epithelium; Signal Transduction | 2020 |
Anti-inflammatory and membrane stabilizing properties of methyl jasmonate in rats.
Topics: Acetates; Animals; Anti-Inflammatory Agents; Cell Membrane; Cyclopentanes; Disease Models, Animal; Edema; Erythrocytes; Glutathione; Humans; Male; Malondialdehyde; Oxylipins; Plant Extracts; Rats; Rats, Wistar | 2017 |
Methyl jasmonate leads to necrosis and apoptosis in hepatocellular carcinoma cells via inhibition of glycolysis and represses tumor growth in mice.
Topics: Acetates; Animals; Apoptosis; Carcinoma, Hepatocellular; Caspases; Cell Line, Tumor; Cell Proliferation; Cyclopentanes; Disease Models, Animal; Drug Resistance, Neoplasm; Energy Metabolism; Glycolysis; Hexokinase; Humans; Liver Neoplasms; Membrane Potential, Mitochondrial; Mice; Mitochondria; Necrosis; Oxylipins; Plant Growth Regulators; Xenograft Model Antitumor Assays | 2017 |
Probable mechanisms involved in the antipsychotic-like activity of methyl jasmonate in mice.
Topics: Acetates; Animals; Antioxidants; Antipsychotic Agents; Brain; Bromocriptine; Cyclopentanes; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Ketamine; Locomotion; Male; Maze Learning; Memory; Memory Disorders; Mice; Oxidative Stress; Oxylipins; Psychotic Disorders; Stereotyped Behavior; Time Factors | 2017 |
Methyl jasmonate attenuated lipopolysaccharide-induced depressive-like behaviour in mice.
Topics: Acetates; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behavior, Animal; Brain; Corticosterone; Cyclopentanes; Depression; Disease Models, Animal; Imipramine; Infusions, Parenteral; Jasminum; Lipopolysaccharides; Male; Mice; Oxidative Stress; Oxylipins; Plant Extracts; Tumor Necrosis Factor-alpha | 2017 |
Pathogenicity and peramivir efficacy in immunocompromised murine models of influenza B virus infection.
Topics: Acids, Carbocyclic; Animals; Antiviral Agents; Bronchoalveolar Lavage Fluid; Cyclopentanes; Cytokines; Disease Models, Animal; Female; Guanidines; Immunocompromised Host; Inflammation Mediators; Influenza B virus; Mice; Mice, Inbred NOD; Mice, SCID; Morbidity; Mortality; Orthomyxoviridae Infections; Viral Load; Virus Replication | 2017 |
Methyl Jasmonate Ameliorates Unpredictable Chronic Mild Stress-Induced Behavioral and Biochemical Alterations in Mouse Brain.
Topics: Acetates; Animals; Behavior, Animal; Brain; Corticosterone; Cyclopentanes; Disease Models, Animal; Glutathione; Imipramine; Male; Malondialdehyde; Mice; Oxylipins; Stress, Psychological; Superoxide Dismutase; Treatment Outcome; Tumor Necrosis Factor-alpha | 2017 |
Lucidone suppresses dengue viral replication through the induction of heme oxygenase-1.
Topics: Animals; Animals, Newborn; Antiviral Agents; Body Weight; Cyclopentanes; Dengue; Dengue Virus; Disease Models, Animal; Heme Oxygenase-1; Mice, Inbred ICR; NF-E2-Related Factor 2; Survival Analysis; Treatment Outcome; Virus Replication | 2018 |
Comparing the Antiseizure and Neuroprotective Efficacy of LY293558, Diazepam, Caramiphen, and LY293558-Caramiphen Combination against Soman in a Rat Model Relevant to the Pediatric Population.
Topics: Animals; Anticonvulsants; Anxiety; Basolateral Nuclear Complex; Behavior, Animal; Child; Cyclopentanes; Diazepam; Disease Models, Animal; Drug Interactions; Humans; Isoquinolines; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Soman; Status Epilepticus; Tetrazoles | 2018 |
Full Protection Against Soman-Induced Seizures and Brain Damage by LY293558 and Caramiphen Combination Treatment in Adult Rats.
Topics: Animals; Anticonvulsants; Body Weight; Brain Injuries; Brain Waves; Cholinesterase Inhibitors; Cyclopentanes; Disease Models, Animal; Drug Therapy, Combination; Electroencephalography; Fluoresceins; Fourier Analysis; Isoquinolines; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Seizures; Soman; Tetrazoles; Time Factors | 2018 |
By Activating Akt/eNOS Bilobalide B Inhibits Autophagy and Promotes Angiogenesis Following Focal Cerebral Ischemia Reperfusion.
Topics: Animals; Apoptosis; Autophagy; Brain; Caspase 3; Cyclopentanes; Disease Models, Animal; Furans; Ginkgolides; Infarction, Middle Cerebral Artery; Male; Microtubule-Associated Proteins; Neovascularization, Physiologic; Neuroprotective Agents; Nitric Oxide; Nitric Oxide Synthase Type III; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Vascular Endothelial Growth Factor A | 2018 |
G-1 exhibit antidepressant effect, increase of hippocampal ERs expression and improve hippocampal redox status in aged female rats.
Topics: Aging; Animals; Cyclopentanes; Disease Models, Animal; Estrogens; Exploratory Behavior; Female; Gene Expression Regulation; Hippocampus; Maze Learning; Membrane Potential, Mitochondrial; Mitochondria; Mood Disorders; Ovariectomy; Oxidation-Reduction; Oxidative Stress; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Superoxide Dismutase; Swimming | 2019 |
Chemical analysis, pharmacological activity and process optimization of the proportion of bilobalide and ginkgolides in Ginkgo biloba extract.
Topics: Animals; Chromatography, High Pressure Liquid; Cyclopentanes; Disease Models, Animal; Embryo, Nonmammalian; Fibrinolytic Agents; Furans; Ginkgo biloba; Ginkgolides; Humans; Mass Spectrometry; Models, Animal; Phenylhydrazines; Plant Extracts; Plant Leaves; Quality Control; Technology, Pharmaceutical; Thrombosis; Zebrafish | 2018 |
Intestinal bitter taste receptor activation alters hormone secretion and imparts metabolic benefits.
Topics: Animals; Body Weight; Cyclopentanes; Diabetes Mellitus, Type 2; Disease Models, Animal; Enteroendocrine Cells; Glucagon-Like Peptide 1; Humulus; Hypoglycemic Agents; Insulin Resistance; Intestinal Mucosa; Intestines; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Receptors, G-Protein-Coupled; Signal Transduction | 2018 |
Simultaneous activation of muscarinic and GABA
Topics: Allosteric Regulation; Animals; Antipsychotic Agents; Benzamides; Brain; Cyclopentanes; Disease Models, Animal; Drug Therapy, Combination; Excitatory Postsynaptic Potentials; Indoles; Male; Mice; Neurotransmitter Agents; Pyridines; Pyrimidines; Receptors, GABA-B; Receptors, Muscarinic; Schizophrenia; Thiophenes | 2019 |
Protective and therapeutic role of Bilobalide in cuprizone-induced demyelination.
Topics: Animals; Autoantibodies; Behavior, Animal; Corpus Callosum; Cuprizone; Cyclopentanes; Cytokines; Demyelinating Diseases; Disease Models, Animal; Furans; Ginkgolides; Humans; Immunity, Humoral; Inflammation; Inflammation Mediators; Male; Mice; Mice, Inbred C57BL; Multiple Sclerosis; Myelin-Oligodendrocyte Glycoprotein; Neuroprotective Agents; Oligodendroglia | 2019 |
The Selective Sphingosine 1-Phosphate Receptor Modulator Etrasimod Regulates Lymphocyte Trafficking and Alleviates Experimental Colitis.
Topics: Acetates; Animals; Biological Transport; Cell Count; Colitis; Cyclopentanes; Disease Models, Animal; Dogs; Heterocyclic Compounds, 3-Ring; Humans; Indoles; Lymphocytes; Male; Mice; Sphingosine-1-Phosphate Receptors | 2019 |
MLN4924 protects against interleukin-17A-induced pulmonary inflammation by disrupting ACT1-mediated signaling.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Line; Chemokine CXCL1; Cyclopentanes; Disease Models, Animal; Enzyme Inhibitors; Humans; Hypertension, Pulmonary; Interleukin-17; Interleukin-1beta; Interleukin-6; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Pneumonia; Pulmonary Disease, Chronic Obstructive; Pyrimidines; TNF Receptor-Associated Factor 6; Ubiquitination | 2019 |
Transient inhibition of neddylation at neonatal stage evokes reversible cardiomyopathy and predisposes the heart to isoproterenol-induced heart failure.
Topics: Animals; Animals, Newborn; Cell Proliferation; Cells, Cultured; Cyclopentanes; Disease Models, Animal; Heart Failure; Hypertrophy, Left Ventricular; Isoproterenol; Myocytes, Cardiac; NEDD8 Protein; Pyrimidines; Rats, Sprague-Dawley; Ubiquitin-Conjugating Enzymes; Ubiquitination; Ventricular Function, Left; Ventricular Remodeling | 2019 |
G-Protein-Coupled Estrogen Receptor Agonist G1 Improves Diastolic Function and Attenuates Cardiac Renin-Angiotensin System Activation in Estrogen-Deficient Hypertensive Rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Cyclopentanes; Diastole; Disease Models, Animal; Estrogens; Female; Hypertension; Myocardium; Ovariectomy; Peptidyl-Dipeptidase A; Proto-Oncogene Mas; Proto-Oncogene Proteins; Quinolines; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Signal Transduction; Ventricular Dysfunction, Left; Ventricular Function, Left | 2019 |
Protective effect of bilobalide on learning and memory impairment in rats with vascular dementia.
Topics: Animals; Apoptosis; Brain; Cyclopentanes; Dementia, Vascular; Disease Models, Animal; Furans; Ginkgo biloba; Ginkgolides; Glutathione; Learning; Male; Malondialdehyde; Memory; Neurons; Neuroprotective Agents; Nitric Oxide Synthase; Plant Leaves; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2013 |
Neurodegeneration after transient brain ischemia in aged mice: beneficial effects of bilobalide.
Topics: Adenosine Triphosphate; Aging; Animals; Brain Infarction; Cyclopentanes; Disease Models, Animal; Extracellular Fluid; Female; Furans; Ginkgolides; Glucose; Glutamic Acid; Infarction, Middle Cerebral Artery; Locomotion; Mice; Microdialysis; Mitochondria; Multienzyme Complexes; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Phosphorylation | 2013 |
Autophagy and cathepsin L are involved in the antinociceptive effect of DMBC in a mouse acetic acid-writhing model.
Topics: Acetic Acid; Analgesics; Animals; Autophagy; Benzylidene Compounds; Cathepsin L; Cyclopentanes; Disease Models, Animal; Epoxy Compounds; Female; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Pain; Pain Measurement; Pyridines; Signal Transduction | 2013 |
DCPIB, a potent volume-regulated anion channel antagonist, attenuates microglia-mediated inflammatory response and neuronal injury following focal cerebral ischemia.
Topics: Animals; Animals, Newborn; Brain Injuries; CD11b Antigen; Cells, Cultured; Coculture Techniques; Cyclopentanes; Cytokines; Disease Models, Animal; Glucose; Hippocampus; Hypoxia; Indans; Infarction, Middle Cerebral Artery; Ki-67 Antigen; Mice; Microglia; Neurons; Rats; Time Factors | 2014 |
The relationship between in vivo antiviral activity and pharmacokinetic parameters of peramivir in influenza virus infection model in mice.
Topics: Acids, Carbocyclic; Animals; Antiviral Agents; Cyclopentanes; Disease Models, Animal; Female; Guanidines; Humans; Influenza, Human; Mice; Mice, Inbred BALB C | 2014 |
A sequential procedure for rapid and accurate identification of putative trichomonacidal agents.
Topics: Animals; Antiprotozoal Agents; Computational Biology; Cyclopentanes; Dimetridazole; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Mice; Parasitic Sensitivity Tests; Quantitative Structure-Activity Relationship; Quinolines; Rats, Wistar; Time Factors; Trichomonas Infections; Trichomonas vaginalis | 2014 |
Expression, pharmacology and functional activity of adenosine A1 receptors in genetic models of Huntington's disease.
Topics: Action Potentials; Adenine; Adenosine A1 Receptor Antagonists; Animals; Cerebral Cortex; Corpus Striatum; Cyclic AMP; Cyclopentanes; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Female; Gene Expression Regulation; Glutamic Acid; Huntingtin Protein; Huntington Disease; In Vitro Techniques; Male; Mice; Mice, Transgenic; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Potassium Chloride; Protein Binding; Receptor, Adenosine A1; Signal Transduction; Statistics, Nonparametric; Synaptic Transmission; Synaptosomes; Transfection; Trinucleotide Repeat Expansion; Tritium; Xanthines | 2014 |
Neuroprotective effects of bilobalide on cerebral ischemia and reperfusion injury are associated with inhibition of pro-inflammatory mediator production and down-regulation of JNK1/2 and p38 MAPK activation.
Topics: Animals; Brain Ischemia; Cyclopentanes; Disease Models, Animal; Down-Regulation; Enzyme Activation; Furans; Ginkgolides; Male; MAP Kinase Signaling System; Neuroprotective Agents; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Reperfusion Injury | 2014 |
Stabilization of HIF through inhibition of Cullin-2 neddylation is protective in mucosal inflammatory responses.
Topics: Animals; Cell Line; Cullin Proteins; Cyclopentanes; Disease Models, Animal; Endopeptidases; Gene Knockdown Techniques; HeLa Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammatory Bowel Diseases; Intestinal Mucosa; Metabolic Networks and Pathways; Mice, Inbred C57BL; NEDD8 Protein; Protease Inhibitors; Protein Stability; Pyrimidines; Ubiquitins | 2015 |
Intravenous peramivir inhibits viral replication, and leads to bacterial clearance and prevention of mortality during murine bacterial co-infection caused by influenza A(H1N1)pdm09 virus and Streptococcus pneumoniae.
Topics: Acids, Carbocyclic; Administration, Intravenous; Animals; Antiviral Agents; Bacterial Load; Coinfection; Cyclopentanes; Cytokines; Disease Models, Animal; Dogs; Guanidines; Influenza A Virus, H1N1 Subtype; Madin Darby Canine Kidney Cells; Mice; Mice, Inbred BALB C; Orthomyxoviridae Infections; Oseltamivir; Pneumococcal Infections; Streptococcus pneumoniae; Viral Load; Virus Replication | 2015 |
Evaluation of adaptogenic-like property of methyl jasmonate in mice exposed to unpredictable chronic mild stress.
Topics: Acetates; Adaptation, Ocular; Adrenal Glands; Analysis of Variance; Animals; Anti-Anxiety Agents; Blood Glucose; Body Weight; Brain; Chronic Disease; Corticosterone; Cyclopentanes; Disease Models, Animal; Dose-Response Relationship, Drug; Glutathione; Liver; Male; Malondialdehyde; Maze Learning; Mice; Neurons; Oxylipins; Stress, Psychological | 2016 |
Neuroprotective potential of the group III mGlu receptor agonist ACPT-I in animal models of ischemic stroke: In vitro and in vivo studies.
Topics: Animals; Brain Ischemia; Cells, Cultured; Cyclopentanes; Disease Models, Animal; Excitatory Amino Acid Agonists; L-Lactate Dehydrogenase; Male; Mice; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Stroke; Tricarboxylic Acids | 2016 |
2-(3',5'-Dimethoxybenzylidene) cyclopentanone, a novel synthetic small-molecule compound, provides neuroprotective effects against ischemic stroke.
Topics: Animals; Apoptosis; Astrocytes; Benzylidene Compounds; Brain; Cells, Cultured; Cerebral Cortex; Cerebrovascular Circulation; Cyclopentanes; Disease Models, Animal; Glial Fibrillary Acidic Protein; Glucose; Hypoxia; Infarction, Middle Cerebral Artery; Muscle Strength; Neurologic Examination; Neuroprotective Agents; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Time Factors | 2016 |
Involvement of GABAB Receptor Signaling in Antipsychotic-like Action of the Novel Orthosteric Agonist of the mGlu4 Receptor, LSP4-2022.
Topics: Amphetamine; Animals; Antipsychotic Agents; Cyclopentanes; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Excitatory Amino Acid Agonists; GABA Agents; Male; Mice, Knockout; Motor Activity; Phosphinic Acids; Pyrimidines; Receptors, GABA-B; Receptors, Metabotropic Glutamate; Recognition, Psychology; Schizophrenia; Social Behavior | 2016 |
GPER activation ameliorates aortic remodeling induced by salt-sensitive hypertension.
Topics: Angiotensin II; Animals; Animals, Congenic; Aorta; Blood Pressure; Cyclopentanes; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Genotype; Glycosaminoglycans; Hypertension; Lipid Peroxidation; Oxidative Stress; Phenylephrine; Quinolines; Rats, Transgenic; Receptors, G-Protein-Coupled; Renin; Sodium Chloride, Dietary; Time Factors; Vascular Remodeling | 2016 |
Neddylation Inhibition Activates the Extrinsic Apoptosis Pathway through ATF4-CHOP-DR5 Axis in Human Esophageal Cancer Cells.
Topics: Activating Transcription Factor 4; Animals; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Biomarkers; Caspase 8; Cell Line, Tumor; Cyclopentanes; Disease Models, Animal; Esophageal Neoplasms; Gene Silencing; Humans; Mice; Models, Biological; Prognosis; Pyrimidines; Receptors, TNF-Related Apoptosis-Inducing Ligand; RNA Interference; Signal Transduction; Transcription Factor CHOP; Xenograft Model Antitumor Assays | 2016 |
Inhibition of neddylation regulates dendritic cell functions via Deptor accumulation driven mTOR inactivation.
Topics: Animals; Apoptosis; Caspase 3; Caspase 7; Cell Differentiation; Cells, Cultured; Cullin Proteins; Cyclopentanes; Cytokines; Dendritic Cells; Disease Models, Animal; Down-Regulation; Enzyme Inhibitors; Humans; Inflammatory Bowel Diseases; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Protein Processing, Post-Translational; Pyrimidines; Signal Transduction; TOR Serine-Threonine Kinases | 2016 |
Inactivation of the CRL4-CDT2-SET8/p21 ubiquitylation and degradation axis underlies the therapeutic efficacy of pevonedistat in melanoma.
Topics: Animals; Antineoplastic Agents; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Cyclopentanes; Disease Models, Animal; Female; Gene Expression; Gene Silencing; Genes, ras; Histone-Lysine N-Methyltransferase; Humans; Kaplan-Meier Estimate; Melanoma; Mice; Mutation; Nuclear Proteins; Prognosis; Protein Stability; Proto-Oncogene Proteins B-raf; Pyrimidines; RNA Interference; Ubiquitin-Protein Ligases; Ubiquitination; Xenograft Model Antitumor Assays | 2016 |
Efficacy of delayed treatment of China-made Peramivir with repeated intravenous injections in a mouse influenza model: from clinical experience to basal experiment.
Topics: Acids, Carbocyclic; Administration, Intravenous; Animals; Antiviral Agents; China; Cyclopentanes; Disease Models, Animal; Drug Administration Schedule; Female; Guanidines; Influenza A Virus, H1N1 Subtype; Injections, Intravenous; Lung; Male; Mice; Orthomyxoviridae Infections; Viral Load; Virus Shedding | 2016 |
G-1 exerts neuroprotective effects through G protein-coupled estrogen receptor 1 following spinal cord injury in mice.
Topics: Animals; Apoptosis; Caspase 3; Cyclopentanes; Disease Models, Animal; Estrogens; Extracellular Signal-Regulated MAP Kinases; Female; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-bcl-2; Quinolines; Receptors, Estrogen; Receptors, G-Protein-Coupled; Signal Transduction; Spinal Cord Injuries | 2016 |
Bilobalide alleviates depression-like behavior and cognitive deficit induced by chronic unpredictable mild stress in mice.
Topics: Animals; Behavior, Animal; Cognition Disorders; Corticosterone; Cyclopentanes; Depression; Discrimination Learning; Disease Models, Animal; Furans; Ginkgolides; Hypothalamo-Hypophyseal System; Male; Maze Learning; Mice; Neuroprotective Agents; Pituitary-Adrenal System; Stress, Psychological | 2016 |
Sigma-1 Receptor Agonism Promotes Mechanical Allodynia After Priming the Nociceptive System with Capsaicin.
Topics: Animals; Capsaicin; Cyclopentanes; Disease Models, Animal; Hyperalgesia; Liver; Male; Mice; Morpholines; Nociception; Pain Measurement; Pain Threshold; Pentazocine; Receptors, sigma; Sigma-1 Receptor | 2016 |
Therapeutic efficacy of peramivir against H5N1 highly pathogenic avian influenza viruses harboring the neuraminidase H275Y mutation.
Topics: Acids, Carbocyclic; Animals; Antiviral Agents; Cyclopentanes; Cytokines; Disease Models, Animal; Guanidines; Humans; Influenza A Virus, H5N1 Subtype; Influenza A Virus, H7N1 Subtype; Influenza A Virus, H7N7 Subtype; Influenza, Human; Lung; Mice; Mutation; Neuraminidase; Orthomyxoviridae Infections; Viral Load; Virus Replication | 2017 |
Deregulated neddylation in liver fibrosis.
Topics: Aging; Analysis of Variance; Animals; Apoptosis; Biopsy, Needle; Cell Proliferation; Cell Survival; Cells, Cultured; Chemokine CCL4; Chemokines; Cyclopentanes; Disease Models, Animal; Hepatic Stellate Cells; Humans; Immunohistochemistry; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; NEDD8 Protein; Pyrimidines; Random Allocation; Signal Transduction; Ubiquitins | 2017 |
A novel CCR2 antagonist inhibits atherogenesis in apoE deficient mice by achieving high receptor occupancy.
Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Carotid Arteries; CHO Cells; Cricetulus; Cyclopentanes; Diet, Atherogenic; Disease Models, Animal; Isoquinolines; Male; Mice; Monocytes; Receptors, CCR2 | 2017 |
G-1 Inhibits Breast Cancer Cell Growth via Targeting Colchicine-Binding Site of Tubulin to Interfere with Microtubule Assembly.
Topics: Animals; Antineoplastic Agents; Apoptosis; Binding Sites; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclopentanes; Disease Models, Animal; Female; Humans; Mice; Microtubules; Protein Binding; Protein Multimerization; Quinolines; Receptors, Estrogen; Tubulin; Tubulin Modulators; Xenograft Model Antitumor Assays | 2017 |
Specific reduction of alcohol's motivational properties by the positive allosteric modulator of the GABAB receptor, GS39783--comparison with the effect of the GABAB receptor direct agonist, baclofen.
Topics: Alcoholism; Animals; Baclofen; Behavior, Animal; Central Nervous System Depressants; Cyclopentanes; Disease Models, Animal; Dose-Response Relationship, Drug; Drinking Behavior; Drug Interactions; Ethanol; GABA Agonists; GABA-B Receptor Agonists; Male; Motivation; Pyrimidines; Rats; Receptors, GABA-B; Reinforcement, Psychology; Self Administration | 2008 |
Peripheral administration of group III mGlu receptor agonist ACPT-I exerts potential antipsychotic effects in rodents.
Topics: Amphetamine; Amphetamines; Animals; Antipsychotic Agents; Behavior, Animal; Cyclopentanes; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Administration Routes; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Frontal Lobe; Hyperkinesis; In Vitro Techniques; Male; Mice; Motor Activity; Psychotic Disorders; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Metabotropic Glutamate; Tricarboxylic Acids | 2008 |
Functional interaction between adenosine A2A and group III metabotropic glutamate receptors to reduce parkinsonian symptoms in rats.
Topics: Adenosine A2 Receptor Antagonists; Animals; Behavior, Animal; Catalepsy; Cyclopentanes; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Haloperidol; Male; Motor Activity; Oxidopamine; Parkinsonian Disorders; Pyridines; Rats; Rats, Wistar; Reaction Time; Receptors, Adenosine A2; Receptors, Metabotropic Glutamate; Tricarboxylic Acids; Xanthines | 2008 |
Effect of cyclopentanone prostaglandin 15-deoxy-delta12,14PGJ2 on early functional recovery from experimental spinal cord injury.
Topics: Animals; Cyclization; Cyclopentanes; Disease Models, Animal; Inflammation Mediators; Ligands; Male; Mice; Mice, Inbred Strains; Neutrophil Infiltration; Peroxisome Proliferator-Activated Receptors; PPAR gamma; Prostaglandin D2; Random Allocation; Recovery of Function; Severity of Illness Index; Spinal Cord Injuries | 2008 |
Intrathecal administration of sigma-1 receptor agonists facilitates nociception: involvement of a protein kinase C-dependent pathway.
Topics: Animals; Antitussive Agents; Calcium Signaling; Cyclopentanes; Disease Models, Animal; Enzyme Inhibitors; Ethylenediamines; Inflammation Mediators; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morpholines; Nociceptors; Pain; Pain Measurement; Pain Threshold; Posterior Horn Cells; Protein Kinase C; Proto-Oncogene Proteins c-fos; Receptors, sigma; Sigma-1 Receptor; Signal Transduction; Spinal Cord | 2008 |
Antinociceptive effects of chronic administration of uncompetitive NMDA receptor antagonists in a rat model of diabetic neuropathic pain.
Topics: Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Cyclopentanes; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Male; Memantine; Pain; Pain Measurement; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Streptozocin; Time Factors | 2009 |
Effects of glutamate and alpha2-noradrenergic receptor antagonists on the development of neurotoxicity produced by chronic rotenone in rats.
Topics: Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Basal Ganglia; Behavior, Animal; Catalepsy; Cyclopentanes; Disease Models, Animal; Dopamine; Excitatory Amino Acid Antagonists; Hypokinesia; Idazoxan; Male; Motor Activity; Muscle Rigidity; Neuroprotective Agents; Neurotoxicity Syndromes; Parkinsonian Disorders; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, Adrenergic, alpha-2; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Rotenone; Serotonin; Substantia Nigra; Time Factors | 2009 |
The mixture of procyanidins extracted from the lotus seed pod and bilobalide ameliorates scopolamine-induced memory impairment in mice.
Topics: Animals; Behavior, Animal; Cyclopentanes; Disease Models, Animal; Drug Therapy, Combination; Furans; Ginkgolides; Lotus; Male; Maze Learning; Memory Disorders; Mice; Mice, Inbred Strains; Plant Extracts; Proanthocyanidins; Reaction Time; Scopolamine; Seeds; Statistics, Nonparametric | 2009 |
Group III mGlu receptor agonist, ACPT-I, attenuates morphine-withdrawal symptoms after peripheral administration in mice.
Topics: Analysis of Variance; Animals; Body Weight; Cyclopentanes; Disease Models, Animal; Dose-Response Relationship, Drug; Head Movements; Male; Mice; Mice, Inbred C57BL; Morphine; Morphine Dependence; Motor Activity; Naloxone; Narcotic Antagonists; Receptors, Metabotropic Glutamate; Substance Withdrawal Syndrome; Time Factors; Tremor; Tricarboxylic Acids | 2009 |
Beneficial role of the GPR30 agonist G-1 in an animal model of multiple sclerosis.
Topics: Adoptive Transfer; Animals; Cyclopentanes; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Estrogen Receptor alpha; Estrogen Receptor beta; Humans; Immunohistochemistry; Interleukin-6; Macrophages; Mice; Mice, Inbred Strains; Microglia; Monocytes; Multiple Sclerosis; Quinolines; Rats; Receptors, Estrogen; Receptors, G-Protein-Coupled; Severity of Illness Index; T-Lymphocytes, Regulatory; Tumor Necrosis Factor-alpha | 2009 |
Activation of a novel estrogen receptor, GPER, is cardioprotective in male and female rats.
Topics: Androstadienes; Animals; Cardiotonic Agents; Cyclopentanes; Disease Models, Animal; Female; In Vitro Techniques; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardial Contraction; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Perfusion; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Receptors, G-Protein-Coupled; Signal Transduction; Ventricular Function, Left; Ventricular Pressure; Wortmannin | 2009 |
Synthesis and in vivo evaluation of 3,4-disubstituted gababutins.
Topics: Amines; Amino Acids; Animals; Anti-Anxiety Agents; Cyclohexanecarboxylic Acids; Cyclopentanes; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Rats | 2010 |
META060 inhibits osteoclastogenesis and matrix metalloproteinases in vitro and reduces bone and cartilage degradation in a mouse model of rheumatoid arthritis.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Blotting, Western; Bone and Bones; Cartilage; Cell Differentiation; Cyclopentanes; Disease Models, Animal; Inflammation; Interleukin-6; Matrix Metalloproteinases; Mice; NF-kappa B; Osteoclasts; RANK Ligand | 2010 |
Combinations of oseltamivir and peramivir for the treatment of influenza A (H1N1) virus infections in cell culture and in mice.
Topics: Acids, Carbocyclic; Animals; Antiviral Agents; Cell Line; Cyclopentanes; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Interactions; Drug Therapy, Combination; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Mice; Mice, Inbred BALB C; Neuraminidase; Orthomyxoviridae Infections; Oseltamivir | 2010 |
Combination of peramivir and rimantadine demonstrate synergistic antiviral effects in sub-lethal influenza A (H3N2) virus mouse model.
Topics: Acids, Carbocyclic; Animals; Antiviral Agents; Cyclopentanes; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Synergism; Female; Guanidines; Influenza A Virus, H3N2 Subtype; Mice; Mice, Inbred BALB C; Orthomyxoviridae Infections; Rimantadine; Survival Rate; Weight Loss | 2010 |
Antidepressant activity of methyl jasmonate, a plant stress hormone in mice.
Topics: Acetates; Animals; Antidepressive Agents; Behavior, Animal; Cyclopentanes; Depression; Disease Models, Animal; Female; Hindlimb Suspension; Immobility Response, Tonic; Male; Mice; Motor Activity; Norepinephrine; Oxylipins; Plant Growth Regulators; Serotonin; Swimming; Yohimbine | 2011 |
A single intramuscular injection of neuraminidase inhibitor peramivir demonstrates antiviral activity against novel pandemic A/California/04/2009 (H1N1) influenza virus infection in mice.
Topics: Acids, Carbocyclic; Animals; Antiviral Agents; Body Weight; Cyclopentanes; Disease Models, Animal; Female; Guanidines; Influenza A Virus, H1N1 Subtype; Injections, Intramuscular; Mice; Mice, Inbred BALB C; Orthomyxoviridae Infections; Rodent Diseases; Survival Analysis | 2011 |
The GABA B receptor agonist CGP44532 and the positive modulator GS39783 reverse some behavioural changes related to positive syndromes of psychosis in mice.
Topics: Animals; Behavior, Animal; Catalepsy; Cyclopentanes; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; Frontal Lobe; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Hyperkinesis; Male; Mice; Motor Activity; Phosphinic Acids; Psychoses, Substance-Induced; Pyrimidines; Receptors, GABA-B; Syndrome | 2011 |
Brain permeability of bilobalide as probed by microdialysis before and after middle cerebral artery occlusion in mice.
Topics: Animals; Biological Availability; Blood-Brain Barrier; Brain; Chromatography, Liquid; Cyclopentanes; Disease Models, Animal; Female; Furans; Ginkgo biloba; Ginkgolides; Infarction, Middle Cerebral Artery; Injections, Intraperitoneal; Mass Spectrometry; Mice; Microdialysis; Permeability; Time Factors | 2010 |
Enhanced efficacy of anticonvulsants when combined with levetiracetam in soman-exposed rats.
Topics: Animals; Anticonvulsants; Antidotes; Chemical Warfare Agents; Cholinesterase Inhibitors; Cholinesterase Reactivators; Cyclopentanes; Disease Models, Animal; Drug Therapy, Combination; Lethal Dose 50; Levetiracetam; Male; Motor Activity; Muscimol; Nicotinic Antagonists; Piracetam; Procyclidine; Quinoxalines; Rats; Rats, Wistar; Reaction Time; Seizures; Soman; Time Factors | 2011 |
EGb761, a Ginkgo biloba extract, is effective against atherosclerosis in vitro, and in a rat model of type 2 diabetes.
Topics: Animals; Apoptosis; Atherosclerosis; Caspase 3; Cell Adhesion; Cell Adhesion Molecules; Cell Movement; Cell Proliferation; Cells, Cultured; Cyclopentanes; Diabetes Mellitus, Type 2; Disease Models, Animal; Furans; Ginkgo biloba; Ginkgolides; Humans; Immunoblotting; Kaempferols; Male; Muscle, Smooth, Vascular; Plant Extracts; Quercetin; Rats; Rats, Inbred OLETF; Reverse Transcriptase Polymerase Chain Reaction; Tunica Intima; U937 Cells | 2011 |
Antiparkinsonian action of a selective group III mGlu receptor agonist is associated with reversal of subthalamonigral overactivity.
Topics: Animals; Cyclopentanes; Disease Models, Animal; Excitatory Amino Acid Agonists; Male; Neural Pathways; Parkinsonian Disorders; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Stereoisomerism; Substantia Nigra; Subthalamic Nucleus; Tricarboxylic Acids | 2012 |
Combinations of favipiravir and peramivir for the treatment of pandemic influenza A/California/04/2009 (H1N1) virus infections in mice.
Topics: Acids, Carbocyclic; Amides; Animals; Antiviral Agents; California; Cyclopentanes; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Female; Guanidines; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Mice; Mice, Inbred BALB C; Pandemics; Pyrazines | 2012 |
Mechanisms of G protein-coupled estrogen receptor-mediated spinal nociception.
Topics: Action Potentials; Analgesics, Opioid; Animals; Animals, Newborn; Behavior, Animal; Benzodioxoles; Calcium; Cells, Cultured; Cyclopentanes; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Female; Gene Expression Regulation; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Microinjections; Morphine; Neurons; Nociception; Nociceptive Pain; Pain Measurement; Patch-Clamp Techniques; Quinolines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Estrogen; Receptors, G-Protein-Coupled; Spinal Cord; Superoxides | 2012 |
Substituted pyrazolones require N2 hydrogen bond donating ability to protect against cytotoxicity from protein aggregation of mutant superoxide dismutase 1.
Topics: Amyotrophic Lateral Sclerosis; Animals; Cell Survival; Cyclopentanes; Disease Models, Animal; Humans; Hydrogen Bonding; Mice; Mutation; PC12 Cells; Protein Folding; Pyrazolones; Superoxide Dismutase; Superoxide Dismutase-1 | 2012 |
The perirhinal cortex of rats: an intricate area for microinfusion of anticonvulsants against soman-induced seizures.
Topics: Animals; Anticonvulsants; Brain Waves; Catheters, Indwelling; Cerebral Cortex; Cyclopentanes; Cyclopropanes; Disease Models, Animal; Drug Delivery Systems; Electroencephalography; Glycine; Infusions, Parenteral; Male; Micromanipulation; Procyclidine; Pyridines; Rats; Rats, Wistar; Reaction Time; Seizures; Soman; Time Factors | 2013 |
Novel 2-aminooctahydrocyclopentalene-3a-carboxamides as potent CCR2 antagonists.
Topics: Administration, Oral; Amides; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cyclopentanes; Disease Models, Animal; Dogs; Half-Life; Haplorhini; Humans; Inflammation; Mice; Mice, Knockout; Protein Binding; Pyridines; Receptors, CCR2; Stereoisomerism; Structure-Activity Relationship | 2013 |
Neuroprotective effects of bilobalide, a component of Ginkgo biloba extract (EGb 761) in global brain ischemia and in excitotoxicity-induced neuronal death.
Topics: Animals; Animals, Newborn; Brain Ischemia; Cell Count; Cell Death; Cell Survival; Cells, Cultured; Cerebellum; Cyclopentanes; Disease Models, Animal; Diterpenes; Dose-Response Relationship, Drug; Electron Transport Complex IV; Furans; Gerbillinae; Ginkgo biloba; Ginkgolides; Glutamic Acid; Glycine; Hippocampus; In Situ Hybridization; In Vitro Techniques; Inhibitory Concentration 50; Male; Membrane Proteins; Plant Extracts; Rats; Reperfusion; RNA, Messenger; Saccharomyces cerevisiae Proteins; Trauma, Nervous System | 2003 |
Genetic and pharmacological evidence of a role for GABA(B) receptors in the modulation of anxiety- and antidepressant-like behavior.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Benzoates; Cyclopentanes; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; GABA-B Receptor Antagonists; Hindlimb Suspension; Male; Maze Learning; Mice; Mice, Inbred BALB C; Mice, Knockout; Motor Activity; Phosphinic Acids; Psychomotor Performance; Pyrimidines; Reaction Time; Receptors, GABA-B; Swimming | 2004 |
Anti-influenza virus activity of peramivir in mice with single intramuscular injection.
Topics: Acids, Carbocyclic; Animals; Antiviral Agents; Cyclopentanes; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Guanidines; Influenza A Virus, H1N1 Subtype; Injections, Intramuscular; Mice; Neuraminidase; Orthomyxoviridae Infections | 2006 |
Evaluation of methyl inosine monophosphate (MIMP) and peramivir activities in a murine model of lethal influenza A virus infection.
Topics: Acids, Carbocyclic; Age Factors; Animals; Antiviral Agents; Body Weight; Cyclopentanes; Disease Models, Animal; Female; Guanidines; Influenza A Virus, H1N1 Subtype; Inosine Monophosphate; Mice; Mice, Inbred BALB C; Orthomyxoviridae Infections | 2006 |
GABA(B) receptor-positive modulation decreases selective molecular and behavioral effects of cocaine.
Topics: Animals; Baclofen; Behavior, Addictive; Brain; Cocaine; Cocaine-Related Disorders; Corpus Striatum; Cyclic AMP Response Element-Binding Protein; Cyclopentanes; Disease Models, Animal; Dopamine; Dopamine and cAMP-Regulated Phosphoprotein 32; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; GABA Agonists; Hyperkinesis; Male; Mice; Mice, Inbred C57BL; Proto-Oncogene Proteins c-fos; Pyrimidines; Receptors, GABA-B; Signal Transduction; Synaptic Transmission | 2007 |
LipoCardium: endothelium-directed cyclopentenone prostaglandin-based liposome formulation that completely reverses atherosclerotic lesions.
Topics: Animals; Atherosclerosis; Cyclopentanes; Disease Models, Animal; Feasibility Studies; Lipid Metabolism; Liposomes; Macrophages; Male; Mice; Prostaglandins; Prostaglandins A; Rats; Rats, Wistar | 2007 |
Extrapolating from animal studies to the efficacy in humans of a pretreatment combination against organophosphate poisoning.
Topics: Animals; Chemical Warfare Agents; Cholinergic Antagonists; Cyclopentanes; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Infusions, Parenteral; Lethal Dose 50; Male; Metabolic Clearance Rate; Organophosphate Poisoning; Organophosphates; Papio anubis; Poisoning; Pyridostigmine Bromide; Sarin; Species Specificity; Treatment Outcome | 2007 |
Anxiolytic-like effect of group III mGlu receptor antagonist is serotonin-dependent.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Conflict, Psychological; Cyclopentanes; Disease Models, Animal; Dose-Response Relationship, Drug; Drinking; Drinking Behavior; Drug Interactions; Electric Stimulation; Flumazenil; GABA Modulators; Glycine; Male; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Ritanserin; Serotonin; Serotonin Antagonists; Tricarboxylic Acids | 2007 |
Drug treatment improves memory in mice.
Topics: Animals; Central Nervous System Stimulants; Chromosomes, Human, Pair 21; Cyclopentanes; Disease Models, Animal; Down Syndrome; Furans; GABA Antagonists; Ginkgolides; Humans; Maze Learning; Memory; Mice; Mice, Transgenic; Neuropsychological Tests; Pentylenetetrazole; Picrotoxin | 2007 |
DCPIB, a specific inhibitor of volume regulated anion channels (VRACs), reduces infarct size in MCAo and the release of glutamate in the ischemic cortical penumbra.
Topics: Animals; Aspartic Acid; Brain Infarction; Chromatography, High Pressure Liquid; Cyclopentanes; Dialysis; Disease Models, Animal; Drug Administration Routes; Fluorenes; Glutamic Acid; Indans; Infarction, Middle Cerebral Artery; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Tetrazolium Salts | 2008 |
Bilobalide inhibits 6-OHDA-induced activation of NF-kappaB and loss of dopaminergic neurons in rat substantia nigra.
Topics: Animals; Cyclopentanes; Disease Models, Animal; Dose-Response Relationship, Drug; Furans; Ginkgolides; Male; Neurons; Neuroprotective Agents; NF-kappa B; Oxidopamine; Parkinson Disease; Rats; Rats, Sprague-Dawley; Substantia Nigra; Sympatholytics | 2008 |
Activation of the spinal sigma-1 receptor enhances NMDA-induced pain via PKC- and PKA-dependent phosphorylation of the NR1 subunit in mice.
Topics: Animals; Behavior, Animal; Blotting, Western; Cyclic AMP-Dependent Protein Kinases; Cyclopentanes; Disease Models, Animal; Dose-Response Relationship, Drug; Ethylenediamines; Immunohistochemistry; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Morpholines; N-Methylaspartate; Pain; Pain Measurement; Phosphorylation; Posterior Horn Cells; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Serine; Sigma-1 Receptor; Signal Processing, Computer-Assisted; Signal Transduction; Spinal Cord; Time Factors | 2008 |
Therapeutic potential of potassium channel openers in peripheral vascular disease and asthma.
Topics: Animals; Asthma; Benzopyrans; Cromakalim; Cyclopentanes; Disease Models, Animal; Humans; Parasympatholytics; Peripheral Vascular Diseases; Potassium Channels; Pyrroles; Rats | 1993 |
In vivo influenza virus-inhibitory effects of the cyclopentane neuraminidase inhibitor RJW-270201.
Topics: Acetamides; Acids, Carbocyclic; Animals; Antiviral Agents; Cyclopentanes; Disease Models, Animal; Female; Guanidines; Influenza A virus; Influenza B virus; Lung; Mice; Mice, Inbred C57BL; Neuraminidase; Orthomyxoviridae Infections; Oseltamivir; Respiratory Function Tests; Ribavirin; Virus Replication | 2001 |
Neurotrophic actions of novel compounds designed from cyclopentenone prostaglandins.
Topics: Animals; Biotin; Brain Ischemia; Cell Survival; Cells, Cultured; Cyclopentanes; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Mice; Microinjections; Nerve Growth Factors; Neurites; Neurons; Neuroprotective Agents; Prostaglandin D2; Prostaglandins; Structure-Activity Relationship | 2001 |
Pharmacodynamic evaluation of RWJ-270201, a novel neuraminidase inhibitor, in a lethal murine model of influenza predicts efficacy for once-daily dosing.
Topics: Acids, Carbocyclic; Animals; Antiviral Agents; Cyclopentanes; Disease Models, Animal; Female; Guanidines; Mice; Mice, Inbred BALB C; Neuraminidase; Orthomyxoviridae Infections; Treatment Outcome | 2001 |
Comparison of efficacies of RWJ-270201, zanamivir, and oseltamivir against H5N1, H9N2, and other avian influenza viruses.
Topics: Acetamides; Acids, Carbocyclic; Animals; Antiviral Agents; Body Weight; Brain; Cyclopentanes; Disease Models, Animal; Dogs; Female; Guanidines; Influenza A virus; Influenza A Virus, H5N1 Subtype; Influenza A Virus, H9N2 Subtype; Lung; Mice; Mice, Inbred BALB C; Neuraminidase; Orthomyxoviridae Infections; Oseltamivir; Pyrans; Sialic Acids; Treatment Outcome; Virus Replication; Zanamivir | 2001 |
The cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J(2) attenuates the development of acute and chronic inflammation.
Topics: Animals; Arthritis, Experimental; Carrageenan; Cyclopentanes; Disease Models, Animal; Immunohistochemistry; Immunologic Factors; Inflammation; Male; Mice; Mice, Inbred BALB C; Pleurisy; Prostaglandin D2 | 2002 |