cyclopenta(cd)pyrene-3-4-oxide has been researched along with Cell-Transformation--Neoplastic* in 1 studies
1 other study(ies) available for cyclopenta(cd)pyrene-3-4-oxide and Cell-Transformation--Neoplastic
Article | Year |
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Mutagenesis and morphological transformation of mammalian cells by a non-bay-region polycyclic cyclopenta(cd)pyrene and its 3,4-oxide.
Cyclopenta(cd)pyrene, a constituent of environmental emissions, has been found to mutate and transform mammalian cells in culture. Cyclopenta(cd)pyrene 3,4-oxide, a presumed metabolite, was found to be a direct-acting mutagen and to transform mammalian cells. These results suggest that cyclopenta(cd)pyrene 3,4-oxide may be an ultimate mutagenic form of the parent hydrocarbon. Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cyclopentanes; Mice; Mutagens; Pyrenes; Structure-Activity Relationship | 1980 |