Page last updated: 2024-10-25

cycloleucine and Pregnancy

cycloleucine has been researched along with Pregnancy in 18 studies

Cycloleucine: An amino acid formed by cyclization of leucine. It has cytostatic, immunosuppressive and antineoplastic activities.
1-aminocyclopentanecarboxylic acid : A non-proteinogenic alpha-amino acid that is cyclopentane substituted at position 1 by amino and carboxy groups.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
" In contrast, neither QA up to 5 mM nor trans-ACPD had a significant toxic effect in either KCl group."1.30NMDA and non-NMDA receptor-mediated excitotoxicity are potentiated in cultured striatal neurons by prior chronic depolarization. ( Chen, Q; Reiner, A; Surmeier, DJ, 1999)
"The cycloleucine block was unaffected by shifts in the holding potential (-60 to +60 mV), and there was no effect of cycloleucine on the reversal potential of the NMDA-evoked current."1.28Cycloleucine blocks NMDA responses in cultured hippocampal neurones under voltage clamp: antagonism at the strychnine-insensitive glycine receptor. ( Hershkowitz, N; Rogawski, MA, 1989)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19902 (11.11)18.7374
1990's11 (61.11)18.2507
2000's5 (27.78)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Meeker, RB1
de Vrijer, B1
Regnault, TR1
Wilkening, RB1
Meschia, G2
Battaglia, FC2
Yoshida, Y1
Tsuchiya, R1
Matsumoto, N1
Morita, M1
Miyakawa, H1
Kudo, Y1
Campusano, JM1
Andrés, ME1
Magendzo, K1
Abarca, J1
Tapia-Arancibia, L1
Bustos, G1
Henderson, GI1
Patwardhan, RV1
McLeroy, S1
Schenker, S1
Reichling, DB1
MacDermott, AB1
Carbó, N2
López-Soriano, FJ2
Argilés, JM2
Kaba, H1
Hayashi, Y1
Higuchi, T1
Nakanishi, S1
Favaron, M1
Manev, RM2
Candeo, P1
Arban, R1
Gabellini, N2
Kozikowski, AP1
Manev, H2
Birrell, GJ1
Marcoux, FW1
Rhodes, PG2
Cai, Z2
Jóźwik, M1
Teng, C1
Timmerman, M1
Chung, M1
Chen, Q1
Surmeier, DJ1
Reiner, A1
Schomberg, SL1
Su, G1
Haworth, RA1
Sun, D1
Hershkowitz, N1
Rogawski, MA1

Other Studies

18 other studies available for cycloleucine and Pregnancy

ArticleYear
Metabotropic and NMDA glutamate receptor interactions with osmotic stimuli in supraoptic neurons.
    Pharmacology, biochemistry, and behavior, 2002, Volume: 73, Issue:2

    Topics: Animals; Calcium Signaling; Cells, Cultured; Cycloleucine; Cyclopropanes; Excitatory Amino Acid Agon

2002
Placental uptake and transport of ACP, a neutral nonmetabolizable amino acid, in an ovine model of fetal growth restriction.
    American journal of physiology. Endocrinology and metabolism, 2004, Volume: 287, Issue:6

    Topics: Animals; Biological Transport; Blood Glucose; Body Temperature; Cycloleucine; Ethanol; Female; Fetal

2004
Ca2+-dependent induction of intracellular Ca2+ oscillation in hippocampal astrocytes during metabotropic glutamate receptor activation.
    Journal of pharmacological sciences, 2005, Volume: 97, Issue:2

    Topics: Animals; Astrocytes; Calcium; Calcium Signaling; Cells, Cultured; Cycloleucine; Female; Hippocampus;

2005
Novel alternative splicing predicts a truncated isoform of the NMDA receptor subunit 1 (NR1) in embryonic rat brain.
    Neurochemical research, 2005, Volume: 30, Issue:4

    Topics: Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Brain; Brain Chemistry; Brain-Der

2005
Inhibition of placental amino acid uptake in rats following acute and chronic ethanol exposure.
    Alcoholism, clinical and experimental research, 1982,Fall, Volume: 6, Issue:4

    Topics: Acetaldehyde; Alanine; Alcoholism; Amino Acids; Aminoisobutyric Acids; Animals; Betaine; Cycloleucin

1982
Brief calcium transients evoked by glutamate receptor agonists in rat dorsal horn neurons: fast kinetics and mechanisms.
    The Journal of physiology, 1993, Volume: 469

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Cells,

1993
Administration of tumor necrosis factor-alpha results in a decreased placental transfer of amino acids in the rat.
    Endocrinology, 1995, Volume: 136, Issue:8

    Topics: Administration, Oral; Amino Acids; Animals; Blood Circulation; Blood Glucose; Cycloleucine; Female;

1995
Induction of an olfactory memory by the activation of a metabotropic glutamate receptor.
    Science (New York, N.Y.), 1994, Jul-08, Volume: 265, Issue:5169

    Topics: Animals; Cycloleucine; Cyclopropanes; Estrus; Female; gamma-Aminobutyric Acid; Glycine; Male; Mice;

1994
Trans-azetidine-2,4-dicarboxylic acid activates neuronal metabotropic receptors.
    Neuroreport, 1993, Volume: 4, Issue:7

    Topics: Animals; Azetidinecarboxylic Acid; Cell Line; Cells, Cultured; Cerebellum; Cycloleucine; DNA; Down-R

1993
Polyamines modulate the function of transfected glutamate receptor mGluR1a.
    Neuroreport, 1993, Volume: 4, Issue:6

    Topics: Biogenic Polyamines; Cell Line; Cycloleucine; Female; Humans; Hydrolysis; Kidney; Phosphatidylinosit

1993
Excitatory amino acid receptor-stimulated phosphoinositide turnover in primary cerebrocortical cultures.
    British journal of pharmacology, 1993, Volume: 109, Issue:2

    Topics: Animals; Calcium; Cells, Cultured; Cerebral Cortex; Cycloleucine; Female; GTP-Binding Proteins; Kynu

1993
Intrauterine hypoxia-ischemia reduces phosphoinositide hydrolysis stimulated by metabotropic glutamate receptor agonists in cultured rat cerebellar granule cells.
    Brain research. Developmental brain research, 1996, May-31, Volume: 93, Issue:1-2

    Topics: Alanine; Animals; Brain Ischemia; Cell Count; Cells, Cultured; Cerebellum; Cycloleucine; Enzyme Inhi

1996
Tumour growth and fetal uptake of amino acids in the pregnant rat.
    European journal of cancer (Oxford, England : 1990), 1996, Volume: 32A, Issue:8

    Topics: Amino Acids; Aminoisobutyric Acids; Animals; Body Weight; Cycloleucine; DDT; Eating; Embryonic and F

1996
Prenatal ethanol exposure enhances glutamate release stimulated by quisqualate in rat cerebellar granule cell cultures.
    Molecular and chemical neuropathology, 1998, Volume: 33, Issue:2

    Topics: Alcoholism; Amino Acids; Animals; Cells, Cultured; Cerebellum; Cycloleucine; Dizocilpine Maleate; Et

1998
Uptake and transport by the ovine placenta of neutral nonmetabolizable amino acids with different transport system affinities.
    Placenta, 1998, Volume: 19, Issue:7

    Topics: Aminoisobutyric Acids; Animals; ATP-Binding Cassette Transporters; beta-Alanine; Biological Transpor

1998
NMDA and non-NMDA receptor-mediated excitotoxicity are potentiated in cultured striatal neurons by prior chronic depolarization.
    Experimental neurology, 1999, Volume: 159, Issue:1

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepi

1999
Stimulation of Na-K-2Cl cotransporter in neurons by activation of Non-NMDA ionotropic receptor and group-I mGluRs.
    Journal of neurophysiology, 2001, Volume: 85, Issue:6

    Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Ca

2001
Cycloleucine blocks NMDA responses in cultured hippocampal neurones under voltage clamp: antagonism at the strychnine-insensitive glycine receptor.
    British journal of pharmacology, 1989, Volume: 98, Issue:3

    Topics: Amino Acids; Animals; Aspartic Acid; Cells, Cultured; Cycloleucine; Electrophysiology; Female; Hippo

1989