cycloleucine has been researched along with Pregnancy in 18 studies
Cycloleucine: An amino acid formed by cyclization of leucine. It has cytostatic, immunosuppressive and antineoplastic activities.
1-aminocyclopentanecarboxylic acid : A non-proteinogenic alpha-amino acid that is cyclopentane substituted at position 1 by amino and carboxy groups.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
Excerpt | Relevance | Reference |
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" In contrast, neither QA up to 5 mM nor trans-ACPD had a significant toxic effect in either KCl group." | 1.30 | NMDA and non-NMDA receptor-mediated excitotoxicity are potentiated in cultured striatal neurons by prior chronic depolarization. ( Chen, Q; Reiner, A; Surmeier, DJ, 1999) |
"The cycloleucine block was unaffected by shifts in the holding potential (-60 to +60 mV), and there was no effect of cycloleucine on the reversal potential of the NMDA-evoked current." | 1.28 | Cycloleucine blocks NMDA responses in cultured hippocampal neurones under voltage clamp: antagonism at the strychnine-insensitive glycine receptor. ( Hershkowitz, N; Rogawski, MA, 1989) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (11.11) | 18.7374 |
1990's | 11 (61.11) | 18.2507 |
2000's | 5 (27.78) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Meeker, RB | 1 |
de Vrijer, B | 1 |
Regnault, TR | 1 |
Wilkening, RB | 1 |
Meschia, G | 2 |
Battaglia, FC | 2 |
Yoshida, Y | 1 |
Tsuchiya, R | 1 |
Matsumoto, N | 1 |
Morita, M | 1 |
Miyakawa, H | 1 |
Kudo, Y | 1 |
Campusano, JM | 1 |
Andrés, ME | 1 |
Magendzo, K | 1 |
Abarca, J | 1 |
Tapia-Arancibia, L | 1 |
Bustos, G | 1 |
Henderson, GI | 1 |
Patwardhan, RV | 1 |
McLeroy, S | 1 |
Schenker, S | 1 |
Reichling, DB | 1 |
MacDermott, AB | 1 |
Carbó, N | 2 |
López-Soriano, FJ | 2 |
Argilés, JM | 2 |
Kaba, H | 1 |
Hayashi, Y | 1 |
Higuchi, T | 1 |
Nakanishi, S | 1 |
Favaron, M | 1 |
Manev, RM | 2 |
Candeo, P | 1 |
Arban, R | 1 |
Gabellini, N | 2 |
Kozikowski, AP | 1 |
Manev, H | 2 |
Birrell, GJ | 1 |
Marcoux, FW | 1 |
Rhodes, PG | 2 |
Cai, Z | 2 |
Jóźwik, M | 1 |
Teng, C | 1 |
Timmerman, M | 1 |
Chung, M | 1 |
Chen, Q | 1 |
Surmeier, DJ | 1 |
Reiner, A | 1 |
Schomberg, SL | 1 |
Su, G | 1 |
Haworth, RA | 1 |
Sun, D | 1 |
Hershkowitz, N | 1 |
Rogawski, MA | 1 |
18 other studies available for cycloleucine and Pregnancy
Article | Year |
---|---|
Metabotropic and NMDA glutamate receptor interactions with osmotic stimuli in supraoptic neurons.
Topics: Animals; Calcium Signaling; Cells, Cultured; Cycloleucine; Cyclopropanes; Excitatory Amino Acid Agon | 2002 |
Placental uptake and transport of ACP, a neutral nonmetabolizable amino acid, in an ovine model of fetal growth restriction.
Topics: Animals; Biological Transport; Blood Glucose; Body Temperature; Cycloleucine; Ethanol; Female; Fetal | 2004 |
Ca2+-dependent induction of intracellular Ca2+ oscillation in hippocampal astrocytes during metabotropic glutamate receptor activation.
Topics: Animals; Astrocytes; Calcium; Calcium Signaling; Cells, Cultured; Cycloleucine; Female; Hippocampus; | 2005 |
Novel alternative splicing predicts a truncated isoform of the NMDA receptor subunit 1 (NR1) in embryonic rat brain.
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Brain; Brain Chemistry; Brain-Der | 2005 |
Inhibition of placental amino acid uptake in rats following acute and chronic ethanol exposure.
Topics: Acetaldehyde; Alanine; Alcoholism; Amino Acids; Aminoisobutyric Acids; Animals; Betaine; Cycloleucin | 1982 |
Brief calcium transients evoked by glutamate receptor agonists in rat dorsal horn neurons: fast kinetics and mechanisms.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Calcium Channels; Cells, | 1993 |
Administration of tumor necrosis factor-alpha results in a decreased placental transfer of amino acids in the rat.
Topics: Administration, Oral; Amino Acids; Animals; Blood Circulation; Blood Glucose; Cycloleucine; Female; | 1995 |
Induction of an olfactory memory by the activation of a metabotropic glutamate receptor.
Topics: Animals; Cycloleucine; Cyclopropanes; Estrus; Female; gamma-Aminobutyric Acid; Glycine; Male; Mice; | 1994 |
Trans-azetidine-2,4-dicarboxylic acid activates neuronal metabotropic receptors.
Topics: Animals; Azetidinecarboxylic Acid; Cell Line; Cells, Cultured; Cerebellum; Cycloleucine; DNA; Down-R | 1993 |
Polyamines modulate the function of transfected glutamate receptor mGluR1a.
Topics: Biogenic Polyamines; Cell Line; Cycloleucine; Female; Humans; Hydrolysis; Kidney; Phosphatidylinosit | 1993 |
Excitatory amino acid receptor-stimulated phosphoinositide turnover in primary cerebrocortical cultures.
Topics: Animals; Calcium; Cells, Cultured; Cerebral Cortex; Cycloleucine; Female; GTP-Binding Proteins; Kynu | 1993 |
Intrauterine hypoxia-ischemia reduces phosphoinositide hydrolysis stimulated by metabotropic glutamate receptor agonists in cultured rat cerebellar granule cells.
Topics: Alanine; Animals; Brain Ischemia; Cell Count; Cells, Cultured; Cerebellum; Cycloleucine; Enzyme Inhi | 1996 |
Tumour growth and fetal uptake of amino acids in the pregnant rat.
Topics: Amino Acids; Aminoisobutyric Acids; Animals; Body Weight; Cycloleucine; DDT; Eating; Embryonic and F | 1996 |
Prenatal ethanol exposure enhances glutamate release stimulated by quisqualate in rat cerebellar granule cell cultures.
Topics: Alcoholism; Amino Acids; Animals; Cells, Cultured; Cerebellum; Cycloleucine; Dizocilpine Maleate; Et | 1998 |
Uptake and transport by the ovine placenta of neutral nonmetabolizable amino acids with different transport system affinities.
Topics: Aminoisobutyric Acids; Animals; ATP-Binding Cassette Transporters; beta-Alanine; Biological Transpor | 1998 |
NMDA and non-NMDA receptor-mediated excitotoxicity are potentiated in cultured striatal neurons by prior chronic depolarization.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anti-Anxiety Agents; Benzodiazepi | 1999 |
Stimulation of Na-K-2Cl cotransporter in neurons by activation of Non-NMDA ionotropic receptor and group-I mGluRs.
Topics: Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Astrocytes; Ca | 2001 |
Cycloleucine blocks NMDA responses in cultured hippocampal neurones under voltage clamp: antagonism at the strychnine-insensitive glycine receptor.
Topics: Amino Acids; Animals; Aspartic Acid; Cells, Cultured; Cycloleucine; Electrophysiology; Female; Hippo | 1989 |