cycloleucine has been researched along with Pain in 11 studies
Cycloleucine: An amino acid formed by cyclization of leucine. It has cytostatic, immunosuppressive and antineoplastic activities.
1-aminocyclopentanecarboxylic acid : A non-proteinogenic alpha-amino acid that is cyclopentane substituted at position 1 by amino and carboxy groups.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The HE was evaluated in acetic acid and glutamate models of pain or by biting behavior following intrathecal (i." | 3.75 | Involvement of glutamate and cytokine pathways on antinociceptive effect of Pfaffia glomerata in mice. ( Baggio, CH; dos Santos, AC; dos Santos, AR; dos Santos, CA; Freitas, CS; Luiz, AP; Marques, MC; Mayer, B; Twardowschy, A, 2009) |
| " This study examined the effects of the metabotropic glutamate receptor agonists (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid ((1S,3R)-ACPD), (S)-3,5-dihydroxyphenylglycine ((S)-3,5-DHPG) and (1S,3S)-1-aminocyclopentane-1,3-dicarboxylic acid ((1S,3S)-ACPD) on the electrically evoked responses of dorsal horn neurones recorded in normal animals and in animals 3 h after the induction of carrageenan inflammation." | 3.70 | Inflammation alters the effects of mGlu receptor agonists on spinal nociceptive neurones. ( Dickenson, AH; Stanfa, LC, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (72.73) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Freitas, CS | 1 |
| Baggio, CH | 1 |
| Twardowschy, A | 1 |
| dos Santos, AC | 1 |
| Mayer, B | 1 |
| Luiz, AP | 1 |
| dos Santos, CA | 1 |
| Marques, MC | 1 |
| dos Santos, AR | 1 |
| Gadotti, VM | 1 |
| Tibola, D | 1 |
| Paszcuk, AF | 1 |
| Rodrigues, AL | 1 |
| Calixto, JB | 1 |
| Santos, AR | 1 |
| Neugebauer, V | 1 |
| Lücke, T | 1 |
| Schaible, HG | 1 |
| Meller, ST | 1 |
| Dykstra, CL | 1 |
| Gebhart, GF | 1 |
| Young, MR | 2 |
| Fleetwood-Walker, SM | 2 |
| Mitchell, R | 1 |
| Dickinson, T | 2 |
| Fisher, K | 1 |
| Coderre, TJ | 1 |
| Blackburn-Munro, G | 1 |
| Sparrow, H | 1 |
| Birch, PJ | 1 |
| Bountra, C | 1 |
| Stanfa, LC | 1 |
| Dickenson, AH | 1 |
| Morisset, V | 1 |
| Nagy, F | 1 |
| Maione, S | 1 |
| Marabese, I | 1 |
| Leyva, J | 1 |
| Palazzo, E | 1 |
| de Novellis, V | 1 |
| Rossi, F | 1 |
| Chen, Y | 1 |
| Bacon, G | 1 |
| Sher, E | 1 |
| Clark, BP | 1 |
| Kallman, MJ | 1 |
| Wright, RA | 1 |
| Johnson, BG | 1 |
| Schoepp, DD | 1 |
| Kingston, AE | 1 |
11 other studies available for cycloleucine and Pain
| Article | Year |
|---|---|
Involvement of glutamate and cytokine pathways on antinociceptive effect of Pfaffia glomerata in mice.
Topics: Acetic Acid; Amaranthaceae; Analgesics; Animals; Behavior, Animal; Cycloleucine; Disease Models, Ani | 2009 |
Contribution of spinal glutamatergic receptors to the antinociception caused by agmatine in mice.
Topics: Agmatine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Analgesics; Animals; Cycloleucin | 2006 |
Requirement of metabotropic glutamate receptors for the generation of inflammation-evoked hyperexcitability in rat spinal cord neurons.
Topics: Acute Disease; Afferent Pathways; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; | 1994 |
Acute mechanical hyperalgesia is produced by coactivation of AMPA and metabotropic glutamate receptors.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cycloleucine; Hot Temperature; Ib | 1993 |
The involvement of metabotropic glutamate receptors and their intracellular signalling pathways in sustained nociceptive transmission in rat dorsal horn neurons.
Topics: Animals; Cycloleucine; Extracellular Space; In Vitro Techniques; Iontophoresis; Male; Mustard Plant; | 1995 |
The contribution of metabotropic glutamate receptors (mGluRs) to formalin-induced nociception.
Topics: Aminobutyrates; Analysis of Variance; Animals; Benzoates; Cycloleucine; Cyclopropanes; Excitatory Am | 1996 |
Behavioural and electrophysiological evidence supporting a role for group I metabotropic glutamate receptors in the mediation of nociceptive inputs to the rat spinal cord.
Topics: Alanine; Animals; Antihypertensive Agents; Behavior, Animal; Benzothiadiazines; Cycloleucine; Electr | 1997 |
Inflammation alters the effects of mGlu receptor agonists on spinal nociceptive neurones.
Topics: Animals; Carrageenan; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; Inflammation; Male; | 1998 |
Nociceptive integration in the rat spinal cord: role of non-linear membrane properties of deep dorsal horn neurons.
Topics: 4-Aminopyridine; Action Potentials; Animals; Cell Membrane; Cycloleucine; Electric Stimulation; Elec | 1998 |
Characterisation of mGluRs which modulate nociception in the PAG of the mouse.
Topics: 2-Amino-5-phosphonovalerate; Analgesics; Animals; Cycloleucine; Excitatory Amino Acid Agonists; Exci | 1998 |
Evaluation of the activity of a novel metabotropic glutamate receptor antagonist (+/-)-2-amino-2-(3-cis and trans-carboxycyclobutyl-3-(9-thioxanthyl)propionic acid) in the in vitro neonatal spinal cord and in an in vivo pain model.
Topics: Acetic Acid; Animals; Animals, Newborn; Cycloleucine; Electrophysiology; Excitatory Amino Acid Antag | 2000 |