cycloleucine has been researched along with Neoplasms in 11 studies
Cycloleucine: An amino acid formed by cyclization of leucine. It has cytostatic, immunosuppressive and antineoplastic activities.
1-aminocyclopentanecarboxylic acid : A non-proteinogenic alpha-amino acid that is cyclopentane substituted at position 1 by amino and carboxy groups.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (81.82) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, R | 1 |
| Elf, S | 1 |
| Shan, C | 1 |
| Kang, HB | 1 |
| Ji, Q | 1 |
| Zhou, L | 1 |
| Hitosugi, T | 1 |
| Zhang, L | 2 |
| Zhang, S | 1 |
| Seo, JH | 1 |
| Xie, J | 1 |
| Tucker, M | 1 |
| Gu, TL | 1 |
| Sudderth, J | 1 |
| Jiang, L | 1 |
| Mitsche, M | 1 |
| DeBerardinis, RJ | 1 |
| Wu, S | 1 |
| Li, Y | 1 |
| Mao, H | 1 |
| Chen, PR | 1 |
| Wang, D | 1 |
| Chen, GZ | 1 |
| Hurwitz, SJ | 1 |
| Lonial, S | 1 |
| Arellano, ML | 1 |
| Khoury, HJ | 1 |
| Khuri, FR | 1 |
| Lee, BH | 1 |
| Lei, Q | 1 |
| Brat, DJ | 1 |
| Ye, K | 1 |
| Boggon, TJ | 1 |
| He, C | 1 |
| Kang, S | 1 |
| Fan, J | 1 |
| Chen, J | 1 |
| Li, C | 1 |
| Gui, G | 1 |
| Qin, A | 1 |
| Zhou, C | 1 |
| Zha, X | 1 |
| BERLINGUET, L | 1 |
| BEGIN, N | 1 |
| BABINEAU, LM | 1 |
| HELSPER, JT | 1 |
| SHARP, GS | 1 |
| BENEFIEL, WW | 1 |
| Hübner, KF | 2 |
| Krauss, S | 1 |
| Washburn, LC | 2 |
| Gibbs, WD | 2 |
| Holloway, EC | 1 |
| Rozencweig, M | 1 |
| Slavik, M | 1 |
| Muggia, FM | 2 |
| Carter, SK | 1 |
| Pardee, AB | 1 |
| Dubrow, R | 1 |
| Sun, TT | 1 |
| Anon, JB | 1 |
| Hayes, RL | 2 |
| Andrews, GA | 1 |
| Washburn, L | 1 |
| Wieland, BW | 1 |
| Butler, TA | 1 |
| Winebrenner, JD | 1 |
| Loew, J | 1 |
| Horwitz, S | 1 |
| De Vis, K | 1 |
| Schelstraete, K | 1 |
| Deman, J | 1 |
| Vermeulen, FL | 1 |
| Sambre, J | 1 |
| Goethals, P | 1 |
| Van Haver, D | 1 |
| Slegers, G | 1 |
| Vandecasteele, C | 1 |
| De Schryver, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of Fluciclovine Uptake in Patients With Cervical, Ovarian Epithelial or Endometrial Cancers. Pilot Study.[NCT03349463] | Phase 4 | 30 participants (Anticipated) | Interventional | 2018-11-14 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for cycloleucine and Neoplasms
| Article | Year |
|---|---|
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; | 2015 |
Overview of Methionine Adenosyltransferase 2A (MAT2A) as an Anticancer Target: Structure, Function, and Inhibitors.
Topics: Humans; Methionine; Methionine Adenosyltransferase; Neoplasms; S-Adenosylmethionine | 2022 |
Control of cell proliferation.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Cell Division; Cyclic AMP | 1977 |
8 other studies available for cycloleucine and Neoplasms
| Article | Year |
|---|---|
Autoradiographic studies of the distribution of 1-aminocyclopentane carboxylic acid in normal and cancerous mice.
Topics: Amino Acids; Animals; Carboxylic Acids; Cycloleucine; Mice; Neoplasms | 1962 |
THE TREATMENT OF MULTIPLE MYELOMA WITH 1-AMINOCYCLOPENTANECARBOXYLIC ACID.
Topics: Antineoplastic Agents; Blood Protein Electrophoresis; Cycloleucine; Cycloparaffins; gamma-Globulins; | 1964 |
Tumor detection with 1-aminocyclopentane and 1-aminocyclobutane C-11-carboxylic acid using positron emission computerized tomography.
Topics: Amino Acids; Amino Acids, Cyclic; Carbon Radioisotopes; Cycloleucine; Humans; Neoplasms; Tomography, | 1981 |
Overview of early and investigational chemotherapeutic agents in solid tumors.
Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Aziridines; Azo Com | 1976 |
Effect of structure on tumor specificity of alicyclic alpha-amino acids.
Topics: Amino Acids; Amino Acids, Cyclic; Animals; Carcinoma, Hepatocellular; Cyclobutanes; Cyclohexanecarbo | 1978 |
Tumor location with 1-aminocyclopentane [11C] carboxylic acid: preliminary clinical trials with single-photon detection.
Topics: Amino Acids; Carbon Radioisotopes; Cycloleucine; Elementary Particles; Female; Humans; Isotope Label | 1977 |
Observations on the human pharmacology of cycloleucine.
Topics: Adult; Amino Acids; Cycloleucine; Half-Life; Humans; Male; Neoplasms | 1977 |
Clinical comparison of 11C-ACPC (aminocyclopentane carboxylic acid) and 13N-ammonia as tumour tracers.
Topics: Abdominal Neoplasms; Amino Acids; Ammonia; Brain Neoplasms; Carbon Radioisotopes; Cycloleucine; Head | 1987 |