cycloleucine has been researched along with Necrosis in 2 studies
Cycloleucine: An amino acid formed by cyclization of leucine. It has cytostatic, immunosuppressive and antineoplastic activities.
1-aminocyclopentanecarboxylic acid : A non-proteinogenic alpha-amino acid that is cyclopentane substituted at position 1 by amino and carboxy groups.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Methionine addiction is a fundamental and general hallmark of cancer caused by enhanced methyl flux." | 1.62 | Triple-Methyl Blockade With Recombinant Methioninase, Cycloleucine, and Azacitidine Arrests a Pancreatic Cancer Patient-Derived Orthotopic Xenograft Model. ( Bouvet, M; Hamada, K; Han, Q; Hoffman, RM; Inubushi, S; Kawaguchi, K; Nishino, H; Sugisawa, N; Tan, Y; Tashiro, Y; Unno, M; Yamamoto, J, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sugisawa, N | 1 |
| Yamamoto, J | 1 |
| Han, Q | 1 |
| Tan, Y | 1 |
| Tashiro, Y | 1 |
| Nishino, H | 1 |
| Inubushi, S | 1 |
| Hamada, K | 1 |
| Kawaguchi, K | 1 |
| Unno, M | 1 |
| Bouvet, M | 1 |
| Hoffman, RM | 1 |
| Chu, C | 1 |
| Mirvish, SS | 1 |
2 other studies available for cycloleucine and Necrosis
| Article | Year |
|---|---|
Triple-Methyl Blockade With Recombinant Methioninase, Cycloleucine, and Azacitidine Arrests a Pancreatic Cancer Patient-Derived Orthotopic Xenograft Model.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Carbon-Sulfur Lyases; Cell Pro | 2021 |
Effects of nine N-nitroso compounds on the specific radioactivity of liver proteins after injection of [14C]leucine into rats.
Topics: Animals; Cycloleucine; Diethylnitrosamine; Dimethylnitrosamine; Leucine; Liver; Liver Neoplasms; Mal | 1977 |