cycloleucine has been researched along with Multiple Myeloma in 6 studies
Cycloleucine: An amino acid formed by cyclization of leucine. It has cytostatic, immunosuppressive and antineoplastic activities.
1-aminocyclopentanecarboxylic acid : A non-proteinogenic alpha-amino acid that is cyclopentane substituted at position 1 by amino and carboxy groups.
Multiple Myeloma: A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| BERGSAGEL, DE | 2 |
| ROSS, SW | 1 |
| BAKER, DT | 1 |
| HAYES, DM | 1 |
| SPURR, CL | 1 |
| MASS, RE | 1 |
| HELSPER, JT | 1 |
| SHARP, GS | 1 |
| BENEFIEL, WW | 1 |
| KRANT, MJ | 1 |
| ISZARD, DM | 1 |
| ABADI, A | 1 |
| CAREY, RW | 1 |
6 other studies available for cycloleucine and Multiple Myeloma
| Article | Year |
|---|---|
Evaluation of new chemotherapeutic agents in the treatment of multiple myeloma. V. 1-Aminocyclopentanecarboxylic acid (NSC-1026).
Topics: Antineoplastic Agents; Cell- and Tissue-Based Therapy; Cycloleucine; Cycloparaffins; Multiple Myelom | 1962 |
Phase II trials of mitomycin C, AB-100, NSC-1026, L-sarcolysin, and meta-sarcolysin, in the treatment of multiple myeloma.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Cell- and Tissue-Based Therapy; Cycloleucine; Cyclopar | 1962 |
The effect of 1-aminocyclopentane carboxylic acid (NSC-1026) on mouse plasmacytoma.
Topics: Antineoplastic Agents; Carboxylic Acids; Cycloleucine; Cycloparaffins; Multiple Myeloma; Plasma Cell | 1961 |
Clinical evaluation of 1-aminocyclopentanecarboxylic acid (NSC-1026) in plasmocytic myeloma.
Topics: Antineoplastic Agents; Cycloleucine; Cycloparaffins; Multiple Myeloma | 1963 |
THE TREATMENT OF MULTIPLE MYELOMA WITH 1-AMINOCYCLOPENTANECARBOXYLIC ACID.
Topics: Antineoplastic Agents; Blood Protein Electrophoresis; Cycloleucine; Cycloparaffins; gamma-Globulins; | 1964 |
Treatment of multiple myeloma with I-aminocyclopentanecarboxylic acid (NSC-1026).
Topics: Amino Acids; Antifibrinolytic Agents; Cell- and Tissue-Based Therapy; Cycloleucine; Cycloparaffins; | 1962 |