cycloleucine has been researched along with Inflammation in 5 studies
Cycloleucine: An amino acid formed by cyclization of leucine. It has cytostatic, immunosuppressive and antineoplastic activities.
1-aminocyclopentanecarboxylic acid : A non-proteinogenic alpha-amino acid that is cyclopentane substituted at position 1 by amino and carboxy groups.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study examined the effects of the metabotropic glutamate receptor agonists (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid ((1S,3R)-ACPD), (S)-3,5-dihydroxyphenylglycine ((S)-3,5-DHPG) and (1S,3S)-1-aminocyclopentane-1,3-dicarboxylic acid ((1S,3S)-ACPD) on the electrically evoked responses of dorsal horn neurones recorded in normal animals and in animals 3 h after the induction of carrageenan inflammation." | 3.70 | Inflammation alters the effects of mGlu receptor agonists on spinal nociceptive neurones. ( Dickenson, AH; Stanfa, LC, 1998) |
| " The NMDA receptor antagonist D-AP5 reversed this effect, leaving the (1S,3R)-ACPD dose-response curve unchanged in naive animals." | 1.30 | mGluR activation reveals a tonic NMDA component in inflammatory hyperalgesia. ( Berthele, A; Boxall, SJ; Tölle, TR; Urban, L; Zieglgänsberger, W, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andrianov, GN | 1 |
| Nozdrachev, AD | 1 |
| Ryzhova, IV | 1 |
| Neugebauer, V | 1 |
| Lücke, T | 1 |
| Schaible, HG | 1 |
| Boxall, SJ | 1 |
| Berthele, A | 1 |
| Tölle, TR | 1 |
| Zieglgänsberger, W | 1 |
| Urban, L | 1 |
| Stanfa, LC | 1 |
| Dickenson, AH | 1 |
| Levine, S | 1 |
| Sowinski, R | 1 |
5 other studies available for cycloleucine and Inflammation
| Article | Year |
|---|---|
The role of defensins in the excitability of the peripheral vestibular system in the frog: evidence for the presence of communication between the immune and nervous systems.
Topics: Acetylcholine; Action Potentials; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; alpha-De | 2007 |
Requirement of metabotropic glutamate receptors for the generation of inflammation-evoked hyperexcitability in rat spinal cord neurons.
Topics: Acute Disease; Afferent Pathways; Alanine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; | 1994 |
mGluR activation reveals a tonic NMDA component in inflammatory hyperalgesia.
Topics: 2-Amino-5-phosphonovalerate; Animals; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Amino | 1998 |
Inflammation alters the effects of mGlu receptor agonists on spinal nociceptive neurones.
Topics: Animals; Carrageenan; Cycloleucine; Excitatory Amino Acid Antagonists; Glycine; Inflammation; Male; | 1998 |
Effects of cycloleucine on macrophages and on experimental allergic encephalomyelitis.
Topics: Adrenalectomy; Amino Acids; Animals; Brain; Cycloleucine; Cyclophosphamide; Drug Administration Sche | 1977 |