cycloleucine has been researched along with Disease Models, Animal in 12 studies
Cycloleucine: An amino acid formed by cyclization of leucine. It has cytostatic, immunosuppressive and antineoplastic activities.
1-aminocyclopentanecarboxylic acid : A non-proteinogenic alpha-amino acid that is cyclopentane substituted at position 1 by amino and carboxy groups.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The HE was evaluated in acetic acid and glutamate models of pain or by biting behavior following intrathecal (i." | 3.75 | Involvement of glutamate and cytokine pathways on antinociceptive effect of Pfaffia glomerata in mice. ( Baggio, CH; dos Santos, AC; dos Santos, AR; dos Santos, CA; Freitas, CS; Luiz, AP; Marques, MC; Mayer, B; Twardowschy, A, 2009) |
| "The spread of experimentally kindled seizures in rats results in sustained increases in plasma vasopressin (VP) and VP mRNA in the supraoptic nucleus (SON)." | 1.30 | Kindled seizures increase metabotropic glutamate receptor expression and function in the rat supraoptic nucleus. ( Al-Ghoul, WM; Greenwood, RS; Meeker, RB, 1998) |
| "Thermal hyperalgesia requires NMDA receptor activation and is primarily mediated by production of nitric oxide." | 1.29 | Spinal mediators of hyperalgesia. ( Gebhart, GF; Meller, ST, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (25.00) | 18.7374 |
| 1990's | 5 (41.67) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kinnamon, KE | 1 |
| Steck, EA | 1 |
| Hanson, WL | 1 |
| Chapman, WL | 1 |
| Zhong, B | 1 |
| Ma, S | 1 |
| Wang, DH | 1 |
| Delto, JC | 1 |
| Kobayashi, T | 1 |
| Benson, M | 1 |
| McKiernan, J | 1 |
| Abate-Shen, C | 1 |
| Freitas, CS | 1 |
| Baggio, CH | 1 |
| Twardowschy, A | 1 |
| dos Santos, AC | 1 |
| Mayer, B | 1 |
| Luiz, AP | 1 |
| dos Santos, CA | 1 |
| Marques, MC | 1 |
| dos Santos, AR | 1 |
| Craan, AG | 1 |
| Meller, ST | 1 |
| Gebhart, GF | 1 |
| Kadowaki, D | 1 |
| Kinno, I | 1 |
| Kadoya, K | 1 |
| Mori, A | 1 |
| Hiramatsu, M | 1 |
| Al-Ghoul, WM | 1 |
| Meeker, RB | 1 |
| Greenwood, RS | 1 |
| Karcz-Kubicha, M | 1 |
| Wedzony, K | 1 |
| Zajaczkowski, W | 1 |
| Danysz, W | 1 |
| Cai, Z | 1 |
| Lin, S | 1 |
| Rhodes, PG | 1 |
| Chiamulera, C | 1 |
| Albertini, P | 1 |
| Valerio, E | 1 |
| Reggiani, A | 1 |
| Deacon, R | 1 |
| Purkiss, P | 1 |
| Green, R | 1 |
| Lumb, M | 1 |
| Perry, J | 1 |
| Chanarin, I | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effectiveness and Safety of Intravesical Docetaxel Instillation After Operation to Prevent Intravesical Recurrence After Radical Nephroureterectomy or Distal Ureterectomy in Upper Urinary Tract Urothelial Carcinoma: A Prospective Study[NCT03209206] | Phase 2 | 84 participants (Anticipated) | Interventional | 2017-06-28 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for cycloleucine and Disease Models, Animal
| Article | Year |
|---|---|
Cystinuria: the disease and its models.
Topics: Animals; Biological Transport; Carnivora; Cycloleucine; Cystine; Cystinuria; Disease Models, Animal; | 1981 |
11 other studies available for cycloleucine and Disease Models, Animal
| Article | Year |
|---|---|
In search of anti-Trypanosoma cruzi drugs: new leads from a mouse model.
Topics: 5-Amino-3-((5-nitro-2-furyl)vinyl)-1,2,4-oxadiazole; Aminoquinolines; Animals; Chagas Disease; Disea | 1977 |
Ablation of TRPV1 Elevates Nocturnal Blood Pressure in Western Diet-fed Mice.
Topics: Animals; Blood Pressure; Circadian Rhythm; Cycloleucine; Diet, Western; Disease Models, Animal; Gene | 2019 |
Preclinical analyses of intravesical chemotherapy for prevention of bladder cancer progression.
Topics: Administration, Intravesical; Animals; Antineoplastic Agents; Cycloleucine; Deoxycytidine; Disease M | 2013 |
Involvement of glutamate and cytokine pathways on antinociceptive effect of Pfaffia glomerata in mice.
Topics: Acetic Acid; Amaranthaceae; Analgesics; Animals; Behavior, Animal; Cycloleucine; Disease Models, Ani | 2009 |
Spinal mediators of hyperalgesia.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Arachidonic Acid; Arginine; Calci | 1994 |
(+-)-1-Amino-1,3-cyclopentane-trans-dicarboxylic acid (trans-ACPD) induced inositol triphosphoric acid formation in the brain of iron-induced epileptic rats and epileptic El mice.
Topics: Animals; Brain; Chlorides; Cycloleucine; Disease Models, Animal; Epilepsy; Ferric Compounds; Inosito | 1994 |
Kindled seizures increase metabotropic glutamate receptor expression and function in the rat supraoptic nucleus.
Topics: Amygdala; Animals; Calcium; Cerebral Cortex; Cycloleucine; Disease Models, Animal; Epilepsy; Immunoh | 1998 |
NMDA receptor antagonists acting at the glycineB site in rat models for antipsychotic-like activity.
Topics: 2-Amino-5-phosphonovalerate; Amphetamine; Animals; Antimetabolites; Antipsychotic Agents; Binding Si | 1999 |
Neuroprotective effects of N-acetylaspartylglutamate in a neonatal rat model of hypoxia-ischemia.
Topics: Amino Acids; Animals; Animals, Newborn; Brain; Carboxypeptidases; Cyclic AMP; Cycloleucine; Dipeptid | 2002 |
Activation of metabotropic receptors has a neuroprotective effect in a rodent model of focal ischaemia.
Topics: Animals; Cerebral Arteries; Cycloleucine; Disease Models, Animal; Ischemic Attack, Transient; Male; | 1992 |
Vitamin B12 neuropathy is not due to failure to methylate myelin basic protein.
Topics: Animals; Arginine; Brain Diseases; Chiroptera; Cycloleucine; Disease Models, Animal; Liver; Methylat | 1986 |