cycloleucine has been researched along with Candidiasis in 5 studies
Cycloleucine: An amino acid formed by cyclization of leucine. It has cytostatic, immunosuppressive and antineoplastic activities.
1-aminocyclopentanecarboxylic acid : A non-proteinogenic alpha-amino acid that is cyclopentane substituted at position 1 by amino and carboxy groups.
Candidiasis: Infection with a fungus of the genus CANDIDA. It is usually a superficial infection of the moist areas of the body and is generally caused by CANDIDA ALBICANS. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " We studied the activity of PLD-118 in escalating dosages against experimental oropharyngeal and esophageal candidiasis (OPEC) caused by fluconazole (FLC)-resistant Candida albicans in immunocompromised rabbits." | 7.72 | Efficacy of PLD-118, a novel inhibitor of candida isoleucyl-tRNA synthetase, against experimental oropharyngeal and esophageal candidiasis caused by fluconazole-resistant C. albicans. ( Bacher, J; Groll, AH; Kelaher, AM; Mickiene, D; Petraitiene, R; Petraitis, V; Sarafandi, AA; Sein, T; Walsh, TJ, 2004) |
| " We studied the activity of PLD-118 in escalating dosages against experimental oropharyngeal and esophageal candidiasis (OPEC) caused by fluconazole (FLC)-resistant Candida albicans in immunocompromised rabbits." | 3.72 | Efficacy of PLD-118, a novel inhibitor of candida isoleucyl-tRNA synthetase, against experimental oropharyngeal and esophageal candidiasis caused by fluconazole-resistant C. albicans. ( Bacher, J; Groll, AH; Kelaher, AM; Mickiene, D; Petraitiene, R; Petraitis, V; Sarafandi, AA; Sein, T; Walsh, TJ, 2004) |
| " Icofungipen shows nearly complete oral bioavailability in a variety of species, and its in vivo efficacy indicates its potential for the oral treatment of yeast infections." | 1.33 | In vitro activity and in vivo efficacy of icofungipen (PLD-118), a novel oral antifungal agent, against the pathogenic yeast Candida albicans. ( Ergovic, G; Galic, T; Geschke, U; Hasenoehrl, A; Marsic, N; Mittendorf, J; Schmidt, A; Schoenfeld, W; Skerlev, M, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Petraitis, V | 2 |
| Petraitiene, R | 2 |
| Kelaher, AM | 2 |
| Sarafandi, AA | 2 |
| Sein, T | 2 |
| Mickiene, D | 2 |
| Bacher, J | 2 |
| Groll, AH | 2 |
| Walsh, TJ | 2 |
| Hasenoehrl, A | 1 |
| Galic, T | 1 |
| Ergovic, G | 1 |
| Marsic, N | 1 |
| Skerlev, M | 1 |
| Mittendorf, J | 1 |
| Geschke, U | 1 |
| Schmidt, A | 1 |
| Schoenfeld, W | 1 |
| Iwamoto, T | 1 |
| Tsujii, E | 1 |
| Ezaki, M | 1 |
| Fujie, A | 1 |
| Hashimoto, S | 1 |
| Okuhara, M | 1 |
| Kohsaka, M | 1 |
| Imanaka, H | 1 |
| Kawabata, K | 1 |
| Inamoto, Y | 1 |
| Oki, T | 1 |
| Hirano, M | 1 |
| Tomatsu, K | 1 |
| Numata, K | 1 |
| Kamei, H | 1 |
5 other studies available for cycloleucine and Candidiasis
| Article | Year |
|---|---|
Efficacy of PLD-118, a novel inhibitor of candida isoleucyl-tRNA synthetase, against experimental oropharyngeal and esophageal candidiasis caused by fluconazole-resistant C. albicans.
Topics: Animals; Antifungal Agents; Area Under Curve; Candida albicans; Candidiasis; Candidiasis, Oral; Cycl | 2004 |
Efficacy, plasma pharmacokinetics, and safety of icofungipen, an inhibitor of Candida isoleucyl-tRNA synthetase, in treatment of experimental disseminated candidiasis in persistently neutropenic rabbits.
Topics: Animals; Antifungal Agents; Candida albicans; Candidiasis; Culture Media; Cycloleucine; Female; Immu | 2005 |
In vitro activity and in vivo efficacy of icofungipen (PLD-118), a novel oral antifungal agent, against the pathogenic yeast Candida albicans.
Topics: Animals; Antifungal Agents; Candida albicans; Candidiasis; Cycloleucine; Drug Interactions; Hydrogen | 2006 |
FR109615, a new antifungal antibiotic from Streptomyces setonii. Taxonomy, fermentation, isolation, physico-chemical properties and biological activity.
Topics: Animals; Antifungal Agents; Candida; Candidiasis; Cycloleucine; Female; Magnetic Resonance Spectrosc | 1990 |
Cispentacin, a new antifungal antibiotic. II. In vitro and in vivo antifungal activities.
Topics: Amphotericin B; Animals; Antifungal Agents; Candida; Candidiasis; Cycloleucine; Drug Evaluation, Pre | 1989 |