Page last updated: 2024-10-25

cycloleucine and Candida Infection

cycloleucine has been researched along with Candida Infection in 5 studies

Cycloleucine: An amino acid formed by cyclization of leucine. It has cytostatic, immunosuppressive and antineoplastic activities.
1-aminocyclopentanecarboxylic acid : A non-proteinogenic alpha-amino acid that is cyclopentane substituted at position 1 by amino and carboxy groups.

Research Excerpts

ExcerptRelevanceReference
" We studied the activity of PLD-118 in escalating dosages against experimental oropharyngeal and esophageal candidiasis (OPEC) caused by fluconazole (FLC)-resistant Candida albicans in immunocompromised rabbits."7.72Efficacy of PLD-118, a novel inhibitor of candida isoleucyl-tRNA synthetase, against experimental oropharyngeal and esophageal candidiasis caused by fluconazole-resistant C. albicans. ( Bacher, J; Groll, AH; Kelaher, AM; Mickiene, D; Petraitiene, R; Petraitis, V; Sarafandi, AA; Sein, T; Walsh, TJ, 2004)
" We studied the activity of PLD-118 in escalating dosages against experimental oropharyngeal and esophageal candidiasis (OPEC) caused by fluconazole (FLC)-resistant Candida albicans in immunocompromised rabbits."3.72Efficacy of PLD-118, a novel inhibitor of candida isoleucyl-tRNA synthetase, against experimental oropharyngeal and esophageal candidiasis caused by fluconazole-resistant C. albicans. ( Bacher, J; Groll, AH; Kelaher, AM; Mickiene, D; Petraitiene, R; Petraitis, V; Sarafandi, AA; Sein, T; Walsh, TJ, 2004)
" Icofungipen shows nearly complete oral bioavailability in a variety of species, and its in vivo efficacy indicates its potential for the oral treatment of yeast infections."1.33In vitro activity and in vivo efficacy of icofungipen (PLD-118), a novel oral antifungal agent, against the pathogenic yeast Candida albicans. ( Ergovic, G; Galic, T; Geschke, U; Hasenoehrl, A; Marsic, N; Mittendorf, J; Schmidt, A; Schoenfeld, W; Skerlev, M, 2006)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's1 (20.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Petraitis, V2
Petraitiene, R2
Kelaher, AM2
Sarafandi, AA2
Sein, T2
Mickiene, D2
Bacher, J2
Groll, AH2
Walsh, TJ2
Hasenoehrl, A1
Galic, T1
Ergovic, G1
Marsic, N1
Skerlev, M1
Mittendorf, J1
Geschke, U1
Schmidt, A1
Schoenfeld, W1
Iwamoto, T1
Tsujii, E1
Ezaki, M1
Fujie, A1
Hashimoto, S1
Okuhara, M1
Kohsaka, M1
Imanaka, H1
Kawabata, K1
Inamoto, Y1
Oki, T1
Hirano, M1
Tomatsu, K1
Numata, K1
Kamei, H1

Other Studies

5 other studies available for cycloleucine and Candida Infection

ArticleYear
Efficacy of PLD-118, a novel inhibitor of candida isoleucyl-tRNA synthetase, against experimental oropharyngeal and esophageal candidiasis caused by fluconazole-resistant C. albicans.
    Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:10

    Topics: Animals; Antifungal Agents; Area Under Curve; Candida albicans; Candidiasis; Candidiasis, Oral; Cycl

2004
Efficacy, plasma pharmacokinetics, and safety of icofungipen, an inhibitor of Candida isoleucyl-tRNA synthetase, in treatment of experimental disseminated candidiasis in persistently neutropenic rabbits.
    Antimicrobial agents and chemotherapy, 2005, Volume: 49, Issue:5

    Topics: Animals; Antifungal Agents; Candida albicans; Candidiasis; Culture Media; Cycloleucine; Female; Immu

2005
In vitro activity and in vivo efficacy of icofungipen (PLD-118), a novel oral antifungal agent, against the pathogenic yeast Candida albicans.
    Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:9

    Topics: Animals; Antifungal Agents; Candida albicans; Candidiasis; Cycloleucine; Drug Interactions; Hydrogen

2006
FR109615, a new antifungal antibiotic from Streptomyces setonii. Taxonomy, fermentation, isolation, physico-chemical properties and biological activity.
    The Journal of antibiotics, 1990, Volume: 43, Issue:1

    Topics: Animals; Antifungal Agents; Candida; Candidiasis; Cycloleucine; Female; Magnetic Resonance Spectrosc

1990
Cispentacin, a new antifungal antibiotic. II. In vitro and in vivo antifungal activities.
    The Journal of antibiotics, 1989, Volume: 42, Issue:12

    Topics: Amphotericin B; Animals; Antifungal Agents; Candida; Candidiasis; Cycloleucine; Drug Evaluation, Pre

1989