cycloleucine has been researched along with Brain Neoplasms in 6 studies
Cycloleucine: An amino acid formed by cyclization of leucine. It has cytostatic, immunosuppressive and antineoplastic activities.
1-aminocyclopentanecarboxylic acid : A non-proteinogenic alpha-amino acid that is cyclopentane substituted at position 1 by amino and carboxy groups.
Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Guanylyl imidodiphosphate (Gpp(NH)p) causes an affinity shift on the L-glutamate dose-response curve, increasing the IC50 value." | 1.30 | Characterization of metabotropic glutamate receptors in rat C6 glioma cells. ( Albasanz, JL; Martín, M; Ros, M, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jarkas, N | 1 |
| Voll, RJ | 1 |
| Williams, L | 1 |
| Camp, VM | 1 |
| Goodman, MM | 1 |
| Miyagawa, T | 2 |
| Oku, T | 2 |
| Sasajima, T | 1 |
| Dasai, R | 1 |
| Beattie, B | 2 |
| Finn, R | 2 |
| Tjuvajev, JG | 1 |
| Blasberg, R | 2 |
| Woodcock, DM | 1 |
| Adams, JK | 1 |
| Allan, RG | 1 |
| Cooper, IA | 1 |
| Albasanz, JL | 1 |
| Ros, M | 1 |
| Martín, M | 1 |
| Uehara, H | 1 |
| Tjuvajev, J | 1 |
| Joshi, R | 1 |
| De Vis, K | 1 |
| Schelstraete, K | 1 |
| Deman, J | 1 |
| Vermeulen, FL | 1 |
| Sambre, J | 1 |
| Goethals, P | 1 |
| Van Haver, D | 1 |
| Slegers, G | 1 |
| Vandecasteele, C | 1 |
| De Schryver, A | 1 |
6 other studies available for cycloleucine and Brain Neoplasms
| Article | Year |
|---|---|
(R,S)-anti-1-amino-2-[18F]fluorocyclopentyl-1-carboxylic acid: synthesis from racemic 2-benzyloxycyclopentanone and biological evaluation for brain tumor imaging with positron emission tomography.
Topics: Amino Acid Transport System y+L; Animals; Brain; Brain Neoplasms; Cell Line, Tumor; Cycloleucine; Cy | 2010 |
Assessment of treatment response by autoradiography with (14)C-aminocyclopentane carboxylic acid, (67)Ga-DTPA, and (18)F-FDG in a herpes simplex virus thymidine kinase/ganciclovir brain tumor model.
Topics: Animals; Autoradiography; Brain Neoplasms; Cell Line, Tumor; Cycloleucine; Fluorodeoxyglucose F18; G | 2003 |
Effect of several inhibitors of enzymatic DNA methylation on the in vivo methylation of different classes of DNA sequences in a cultured human cell line.
Topics: 5-Methylcytosine; Adenosine; Azacitidine; Brain Neoplasms; Cell Division; Cell Line; Cycloleucine; C | 1983 |
Characterization of metabotropic glutamate receptors in rat C6 glioma cells.
Topics: Animals; Brain Neoplasms; Cell Membrane; Cycloleucine; Excitatory Amino Acid Agonists; Excitatory Am | 1997 |
Imaging experimental brain tumors with 1-aminocyclopentane carboxylic acid and alpha-aminoisobutyric acid: comparison to fluorodeoxyglucose and diethylenetriaminepentaacetic acid in morphologically defined tumor regions.
Topics: Aminoisobutyric Acids; Animals; Autoradiography; Brain Neoplasms; Cycloleucine; Fluorodeoxyglucose F | 1997 |
Clinical comparison of 11C-ACPC (aminocyclopentane carboxylic acid) and 13N-ammonia as tumour tracers.
Topics: Abdominal Neoplasms; Amino Acids; Ammonia; Brain Neoplasms; Carbon Radioisotopes; Cycloleucine; Head | 1987 |