cycloleucine has been researched along with Brain Injuries in 4 studies
Cycloleucine: An amino acid formed by cyclization of leucine. It has cytostatic, immunosuppressive and antineoplastic activities.
1-aminocyclopentanecarboxylic acid : A non-proteinogenic alpha-amino acid that is cyclopentane substituted at position 1 by amino and carboxy groups.
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "1S,3R-ACPD-induced seizures were antagonized by systemic administration of dantrolene, an inhibitor of intracellular calcium mobilization, but not by the ionotropic glutamate antagonists MK-801 or GYKI-52466." | 1.29 | Seizures and brain injury in neonatal rats induced by 1S,3R-ACPD, a metabotropic glutamate receptor agonist. ( Fix, AS; McDonald, JW; Schoepp, DD; Tizzano, JP, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Delahunty, TM | 1 |
| Jiang, JY | 1 |
| Black, RT | 1 |
| Lyeth, BG | 1 |
| McDonald, JW | 1 |
| Fix, AS | 1 |
| Tizzano, JP | 1 |
| Schoepp, DD | 1 |
| Weber, JT | 2 |
| Rzigalinski, BA | 2 |
| Willoughby, KA | 2 |
| Moore, SF | 1 |
| Ellis, EF | 2 |
| Floyd, CL | 1 |
| Sitterding, HA | 1 |
4 other studies available for cycloleucine and Brain Injuries
| Article | Year |
|---|---|
Differential modulation of carbachol and trans-ACPD-stimulated phosphoinositide turnover following traumatic brain injury.
Topics: Animals; Brain Injuries; Carbachol; Cycloleucine; Male; Neurotoxins; Phosphatidylinositols; Rats; Ra | 1995 |
Seizures and brain injury in neonatal rats induced by 1S,3R-ACPD, a metabotropic glutamate receptor agonist.
Topics: Animals; Animals, Newborn; Anti-Anxiety Agents; Benzodiazepines; Brain Injuries; Cell Nucleus; Corpu | 1993 |
Alterations in calcium-mediated signal transduction after traumatic injury of cortical neurons.
Topics: Animals; Brain Injuries; Calcium; Calcium Signaling; Cells, Cultured; Cerebral Cortex; Cycloleucine; | 1999 |
Traumatic injury of cultured astrocytes alters inositol (1,4,5)-trisphosphate-mediated signaling.
Topics: Animals; Animals, Newborn; Astrocytes; Brain Injuries; Cells, Cultured; Cycloleucine; Estrenes; Extr | 2001 |